[Hub]/) : Traits : Hair/balding pattern: Pattern 2 : ← →

chr17:44,788,310-45,796,313

Best TWAS P=5.12e-10 · Best GWAS P=7.56e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	LRRC37A2	0.34	0.52	lasso	4	0.52	1.2e-49	6.1	6.1	1.1e-09	1.00	0.01	0.99	FALSE
2	GTEx	Adipose Visceral Omentum	LRRC37A2	0.32	0.48	lasso	5	0.50	2.9e-29	6.1	6.2	7.8e-10	0.99	0.01	0.99	FALSE
3	GTEx	Adrenal Gland	LRRC37A2	0.47	0.50	enet	30	0.54	5.9e-23	6.1	5.6	2.3e-08	0.96	0.01	0.99	FALSE
4	GTEx	Artery Aorta	WNT3	0.16	0.22	lasso	7	0.24	3.6e-13	5.4	5.6	2.2e-08	0.89	0.10	0.90	FALSE
5	GTEx	Artery Aorta	LRRC37A2	0.31	0.44	lasso	3	0.44	4.8e-26	6.1	6.2	7.9e-10	1.00	0.01	0.99	FALSE
6	GTEx	Artery Coronary	WNT3	0.13	0.04	lasso	3	0.02	9.4e-02	5.9	6.0	1.8e-09	0.97	0.02	0.92	FALSE
7	GTEx	Artery Coronary	LRRC37A2	0.38	0.48	lasso	13	0.48	5.5e-18	6.1	6.1	8.9e-10	1.00	0.01	0.99	FALSE
8	GTEx	Artery Tibial	LRRC37A2	0.25	0.41	lasso	8	0.40	1.2e-33	6.1	6.1	8.7e-10	1.00	0.01	0.99	FALSE
9	GTEx	Brain Caudate basal ganglia	LRRC37A2	0.44	0.62	enet	34	0.68	1.2e-25	5.9	5.7	1.3e-08	0.96	0.01	0.99	FALSE
10	GTEx	Brain Cerebellar Hemisphere	LRRC37A2	0.48	0.60	lasso	11	0.58	3.2e-18	6.1	6.1	9.1e-10	1.00	0.01	0.99	FALSE
11	GTEx	Brain Cerebellum	LRRC37A2	0.54	0.67	enet	23	0.69	3.2e-27	6.1	6.1	9.0e-10	0.99	0.01	0.99	FALSE
12	GTEx	Brain Cortex	LRRC37A2	0.46	0.50	enet	19	0.56	1.2e-18	6.1	5.7	1.1e-08	0.97	0.01	0.99	FALSE
13	GTEx	Brain Frontal Cortex BA9	LRRC37A2	0.45	0.50	lasso	8	0.59	3.1e-19	6.1	6.1	1.3e-09	0.98	0.02	0.98	FALSE
14	GTEx	Brain Hippocampus	LRRC37A2	0.44	0.56	lasso	9	0.58	1.1e-16	6.1	6.1	9.2e-10	1.00	0.01	0.99	FALSE
15	GTEx	Brain Hypothalamus	LRRC37A2	0.56	0.59	lasso	8	0.62	1.9e-18	6.1	6.1	1.1e-09	0.99	0.02	0.98	FALSE
16	GTEx	Brain Nucleus accumbens basal ganglia	WNT3	0.22	0.08	lasso	3	0.01	1.9e-01	5.1	5.2	2.0e-07	0.86	0.04	0.32	FALSE
17	GTEx	Brain Nucleus accumbens basal ganglia	LRRC37A2	0.46	0.62	lasso	11	0.66	3.4e-23	6.1	6.1	9.4e-10	0.99	0.01	0.99	FALSE
18	GTEx	Brain Putamen basal ganglia	LRRC37A2	0.41	0.62	lasso	12	0.62	1.6e-18	6.1	6.2	7.5e-10	1.00	0.01	0.99	FALSE
19	GTEx	Breast Mammary Tissue	LRRC37A2	0.38	0.44	lasso	2	0.44	8.3e-25	6.1	6.2	8.0e-10	1.00	0.01	0.99	FALSE
20	GTEx	Breast Mammary Tissue (Male)	LRRC37A2	0.37	0.24	lasso	5	0.18	6.3e-05	6.1	6.2	6.4e-10	0.99	0.01	0.98	FALSE
21	GTEx	Breast Mammary Tissue (Female)	LRRC37A2	0.24	0.24	lasso	5	0.23	1.8e-07	6.1	6.1	9.0e-10	1.00	0.01	0.99	FALSE
22	GTEx	Cells EBV-transformed lymphocytes	LRRC37A2	0.20	0.06	lasso	9	0.05	7.8e-03	5.9	5.4	5.9e-08	0.93	0.02	0.90	FALSE
23	GTEx	Cells Transformed fibroblasts	NSF	0.06	0.03	lasso	4	0.02	5.7e-03	6.1	5.9	3.0e-09	0.93	0.01	0.95	FALSE
24	GTEx	Colon Sigmoid	LRRC37A2	0.42	0.63	lasso	14	0.64	1.1e-28	5.9	6.2	7.8e-10	1.00	0.01	0.99	FALSE
25	GTEx	Colon Transverse	WNT3	0.10	0.07	enet	10	0.09	6.4e-05	5.4	5.6	2.1e-08	0.89	0.08	0.89	FALSE
26	GTEx	Colon Transverse	LRRC37A2	0.37	0.41	enet	26	0.40	1.4e-20	6.1	6.0	1.9e-09	0.99	0.01	0.99	FALSE
27	GTEx	Esophagus Gastroesophageal Junction	WNT3	0.15	0.06	lasso	2	0.05	9.0e-03	5.7	5.7	1.5e-08	0.89	0.06	0.77	FALSE
28	GTEx	Esophagus Gastroesophageal Junction	LRRC37A2	0.38	0.49	enet	19	0.50	1.4e-20	6.1	5.8	8.0e-09	0.96	0.01	0.99	FALSE
29	GTEx	Esophagus Mucosa	LRRC37A2	0.24	0.17	lasso	9	0.22	4.9e-15	6.1	5.7	1.6e-08	0.95	0.02	0.98	FALSE
30	GTEx	Esophagus Mucosa	LRRC37A17P	0.14	0.12	lasso	4	0.12	1.6e-08	6.1	-6.2	7.9e-10	-0.99	0.01	0.99	FALSE
31	GTEx	Esophagus Muscularis	WNT3	0.13	0.13	lasso	3	0.12	1.3e-07	5.5	5.5	3.9e-08	0.89	0.17	0.83	FALSE
32	GTEx	Esophagus Muscularis	LRRC37A2	0.31	0.51	enet	22	0.51	4.5e-35	6.1	6.2	5.1e-10	0.99	0.01	0.99	TRUE
33	GTEx	Heart Atrial Appendage	WNT3	0.20	0.15	lasso	3	0.13	2.3e-06	5.8	5.5	4.2e-08	0.89	0.06	0.94	FALSE
34	GTEx	Heart Atrial Appendage	LRRC37A2	0.35	0.43	lasso	10	0.42	1.6e-20	6.1	6.2	7.8e-10	1.00	0.01	0.99	FALSE
35	GTEx	Heart Left Ventricle	LRRC37A2	0.23	0.38	enet	12	0.38	5.0e-21	6.1	6.2	7.7e-10	1.00	0.01	0.99	FALSE
36	GTEx	Liver	LRRC37A2	0.42	0.36	lasso	6	0.36	8.4e-11	6.1	5.8	7.3e-09	0.99	0.01	0.99	FALSE
37	GTEx	Lung	WNT3	0.15	0.13	lasso	3	0.11	9.9e-09	5.4	5.5	4.0e-08	0.89	0.12	0.88	FALSE
38	GTEx	Lung	LRRC37A2	0.30	0.43	lasso	2	0.43	2.2e-35	6.1	6.1	9.3e-10	1.00	0.01	0.99	FALSE
39	GTEx	Muscle Skeletal	LRRC37A2	0.35	0.33	enet	23	0.40	1.9e-42	6.1	5.2	1.6e-07	0.89	0.01	0.99	FALSE
40	GTEx	Nerve Tibial	WNT3	0.15	0.14	lasso	2	0.14	5.4e-10	5.5	5.6	2.1e-08	0.89	0.11	0.89	FALSE
41	GTEx	Nerve Tibial	LRRC37A2	0.40	0.51	enet	24	0.55	1.8e-45	6.1	5.7	1.3e-08	0.97	0.01	0.99	FALSE
42	GTEx	Ovary	LRRC37A2	0.51	0.44	lasso	8	0.45	1.3e-12	6.1	6.0	2.4e-09	0.99	0.01	0.99	FALSE
43	GTEx	Pancreas	WNT3	0.21	0.13	enet	14	0.16	4.3e-07	5.1	5.7	1.3e-08	0.90	0.05	0.95	FALSE
44	GTEx	Pancreas	LRRC37A2	0.30	0.37	lasso	9	0.38	6.0e-17	6.1	6.2	7.5e-10	0.99	0.01	0.99	FALSE
45	GTEx	Pituitary	LRRC37A2	0.46	0.26	enet	27	0.32	1.1e-08	6.1	5.5	2.9e-08	0.91	0.02	0.98	FALSE
46	GTEx	Prostate	LRRC37A2	0.34	0.45	lasso	6	0.43	3.4e-12	6.1	6.1	9.7e-10	1.00	0.01	0.99	FALSE
47	GTEx	Skin Not Sun Exposed Suprapubic	LRRC37A2	0.32	0.31	lasso	4	0.35	4.8e-20	6.1	5.6	2.8e-08	0.96	0.01	0.99	FALSE
48	GTEx	Skin Not Sun Exposed Suprapubic	LRRC37A17P	0.15	0.07	lasso	7	0.07	1.4e-04	6.1	-5.8	5.1e-09	-0.98	0.01	0.98	FALSE
49	GTEx	Skin Sun Exposed Lower leg	LRRC37A2	0.22	0.33	enet	20	0.35	2.3e-30	6.1	5.8	8.1e-09	0.96	0.01	0.99	FALSE
50	GTEx	Small Intestine Terminal Ileum	LRRC37A2	0.38	0.28	enet	24	0.36	6.8e-09	6.1	5.6	2.7e-08	0.93	0.02	0.98	FALSE
51	GTEx	Spleen	LRRC37A2	0.37	0.34	lasso	3	0.40	2.2e-11	6.1	6.1	9.9e-10	0.98	0.02	0.98	FALSE
52	GTEx	Stomach	WNT3	0.09	0.08	lasso	10	0.06	6.4e-04	5.8	5.8	6.2e-09	0.92	0.06	0.86	FALSE
53	GTEx	Stomach	LRRC37A2	0.32	0.44	lasso	7	0.43	1.3e-22	6.1	6.1	9.1e-10	1.00	0.01	0.99	FALSE
54	GTEx	Testis	NSF	0.10	0.10	lasso	4	0.06	7.9e-04	6.1	6.1	8.8e-10	1.00	0.01	0.94	FALSE
55	GTEx	Testis	WNT3	0.14	0.10	enet	10	0.14	9.9e-07	5.7	5.2	2.0e-07	0.89	0.08	0.91	FALSE
56	GTEx	Testis	LRRC37A17P	0.16	0.21	lasso	6	0.19	1.0e-08	6.1	-6.1	8.9e-10	-1.00	0.01	0.99	FALSE
57	GTEx	Thyroid	WNT3	0.27	0.32	lasso	1	0.30	1.6e-23	5.1	5.1	2.9e-07	0.88	0.76	0.24	FALSE
58	GTEx	Thyroid	LRRC37A2	0.25	0.41	lasso	10	0.41	3.7e-33	6.1	6.2	7.0e-10	1.00	0.01	0.99	FALSE
59	GTEx	Uterus	LRRC37A2	0.64	0.54	lasso	11	0.56	1.1e-13	6.1	5.7	9.9e-09	0.97	0.01	0.99	FALSE
60	GTEx	Vagina	LRRC37A2	0.42	0.34	enet	18	0.37	2.6e-09	6.1	5.7	1.1e-08	0.94	0.01	0.99	FALSE
61	GTEx	Whole Blood	LRRC37A2	0.22	0.27	lasso	9	0.25	3.0e-23	6.1	6.1	9.5e-10	1.00	0.01	0.99	FALSE
62	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	LRRC37A2	0.28	0.39	lasso	6	0.43	6.6e-40	6.1	5.6	2.2e-08	0.96	0.01	0.99	FALSE
63	The Cancer Genome Atlas	Breast Invasive Carcinoma	LRRC37A2	0.24	0.33	lasso	9	0.33	3.2e-70	6.1	5.9	3.2e-09	0.99	0.01	0.99	FALSE
64	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	LRRC37A2	0.44	0.46	blup	48	0.48	1.8e-26	6.1	5.5	2.8e-08	0.93	0.01	0.99	FALSE
65	The Cancer Genome Atlas	Colon Adenocarcinoma	LRRC37A2	0.21	0.21	blup	48	0.21	3.0e-12	6.1	5.4	5.3e-08	0.96	0.01	0.99	FALSE
66	The Cancer Genome Atlas	Esophageal Carcinoma	LRRC37A2	0.46	0.24	blup	47	0.29	1.1e-09	6.1	5.2	1.5e-07	0.90	0.01	0.99	FALSE
67	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LRRC37A2	0.19	0.30	lasso	4	0.30	1.4e-33	6.1	6.0	2.1e-09	0.99	0.01	0.99	FALSE
68	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LRRC37A2	0.33	0.35	lasso	4	0.41	7.2e-50	6.1	5.6	2.4e-08	0.94	0.01	0.99	FALSE
69	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	WNT3	0.04	0.03	blup	57	0.04	3.2e-05	6.1	6.1	1.1e-09	0.95	0.01	0.98	FALSE
70	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	LRRC37A2	0.33	0.34	lasso	7	0.34	6.3e-20	6.1	5.8	5.0e-09	0.98	0.01	0.99	FALSE
71	The Cancer Genome Atlas	Brain Lower Grade Glioma	LRRC37A2	0.43	0.51	enet	14	0.54	9.2e-72	6.1	5.6	2.1e-08	0.97	0.01	0.99	FALSE
72	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	LRRC37A2	0.31	0.33	lasso	6	0.36	9.1e-18	6.1	6.0	2.0e-09	0.96	0.01	0.99	FALSE
73	The Cancer Genome Atlas	Lung Adenocarcinoma	LRRC37A2	0.27	0.36	enet	25	0.40	1.5e-50	6.1	6.0	2.3e-09	0.95	0.01	0.99	FALSE
74	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LRRC37A2	0.27	0.34	enet	13	0.36	1.5e-42	6.1	5.2	1.6e-07	0.95	0.01	0.99	FALSE
75	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LRRC37A2	0.19	0.25	enet	8	0.28	2.0e-19	6.1	5.8	8.9e-09	0.94	0.01	0.99	FALSE
76	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LRRC37A2	0.28	0.36	lasso	6	0.36	3.3e-16	6.1	6.1	9.1e-10	0.98	0.01	0.99	FALSE
77	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LRRC37A2	0.29	0.29	lasso	9	0.26	5.4e-11	6.1	6.1	8.9e-10	1.00	0.01	0.99	FALSE
78	The Cancer Genome Atlas	Prostate Adenocarcinoma	LRRC37A2	0.35	0.43	enet	18	0.46	5.3e-54	5.9	5.5	3.0e-08	0.94	0.02	0.98	FALSE
79	The Cancer Genome Atlas	Prostate Adenocarcinoma	WNT3	0.06	0.11	lasso	2	0.11	7.6e-12	5.1	5.2	2.4e-07	0.89	0.11	0.89	FALSE
80	The Cancer Genome Atlas	Rectum Adenocarcinoma	LRRC37A2	0.32	0.24	enet	8	0.33	1.4e-08	6.1	5.4	7.6e-08	0.95	0.02	0.98	FALSE
81	The Cancer Genome Atlas	Skin Cutaneous Melanoma	LRRC37A2	0.37	0.27	enet	15	0.34	5.2e-10	6.1	5.4	7.7e-08	0.92	0.01	0.99	FALSE
82	The Cancer Genome Atlas	Stomach Adenocarcinoma	LRRC37A2	0.27	0.27	lasso	6	0.30	2.8e-22	6.1	5.5	2.9e-08	0.95	0.01	0.99	FALSE
83	The Cancer Genome Atlas	Thyroid Carcinoma	LRRC37A2	0.44	0.46	lasso	10	0.50	4.3e-56	6.1	6.0	2.1e-09	0.98	0.01	0.99	FALSE
84	The Cancer Genome Atlas	Thyroid Carcinoma	WNT3	0.05	0.05	lasso	3	0.06	2.7e-06	5.4	5.3	1.2e-07	0.89	0.12	0.87	FALSE
85	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	LRRC37A2	0.34	0.21	blup	48	0.29	9.1e-09	6.1	5.5	3.1e-08	0.89	0.02	0.98	FALSE