[Hub]/) : Traits : Age when periods started (menarche) : ← →

chr7:73,425,238-75,842,792

Best TWAS P=4.79e-13 · Best GWAS P=3.26e-10 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	PMS2P5	0.29	0.05	enet	20	0.14	7.3e-17	-4.7	6.0	2.6e-09	-0.52	0.88	0.12	FALSE
2	CommonMind	Brain Pre-frontal Cortex	POM121C	0.08	0.05	lasso	2	0.04	1.1e-05	5.3	5.2	2.0e-07	-0.06	0.01	0.99	FALSE
3	CommonMind	Brain Pre-frontal Cortex	STAG3L1	0.23	0.14	enet	13	0.17	1.0e-19	5.3	5.2	1.5e-07	-0.02	0.01	0.99	FALSE
4	CommonMind	Brain Pre-frontal Cortex	STAG3L2	0.33	0.09	enet	3	0.18	7.3e-21	-3.5	6.0	2.5e-09	-0.44	0.99	0.00	FALSE
5	GTEx	Adipose Subcutaneous	PMS2P3	0.15	0.12	lasso	3	0.10	9.8e-09	5.6	5.7	1.2e-08	-0.05	0.00	1.00	TRUE
6	GTEx	Adipose Subcutaneous	STAG3L2	0.16	0.03	enet	11	0.09	1.0e-07	-4.7	7.1	1.6e-12	-0.76	0.01	0.99	FALSE
7	GTEx	Adipose Subcutaneous	TRIM73	0.20	0.12	enet	26	0.12	2.0e-10	5.3	5.5	3.6e-08	-0.01	0.00	1.00	FALSE
8	GTEx	Adipose Subcutaneous	AC004166.6	0.09	0.08	lasso	2	0.07	3.9e-06	-6.3	-6.1	1.3e-09	0.99	0.00	1.00	FALSE
9	GTEx	Adipose Visceral Omentum	STAG3L1	0.20	0.19	lasso	3	0.17	2.3e-09	5.3	5.2	2.5e-07	-0.05	0.00	1.00	FALSE
10	GTEx	Adrenal Gland	STAG3L2	0.14	0.07	enet	3	0.11	1.2e-04	-4.4	5.5	3.8e-08	-0.86	0.01	0.91	FALSE
11	GTEx	Artery Aorta	PMS2P5	0.33	0.10	lasso	6	0.17	1.3e-09	-4.7	5.4	5.9e-08	-0.46	0.61	0.36	FALSE
12	GTEx	Artery Aorta	STAG3L1	0.18	0.03	lasso	4	0.08	3.9e-05	5.3	5.2	2.3e-07	-0.05	0.00	1.00	FALSE
13	GTEx	Artery Coronary	PMS2P5	0.15	-0.01	enet	13	0.08	1.4e-03	-4.7	6.0	2.5e-09	-0.59	0.02	0.61	FALSE
14	GTEx	Artery Coronary	STAG3L2	0.16	0.10	lasso	3	0.11	1.5e-04	-4.7	5.7	9.5e-09	-0.78	0.01	0.95	FALSE
15	GTEx	Artery Coronary	STAG3L1	0.28	0.13	lasso	4	0.17	1.8e-06	5.3	5.3	1.3e-07	-0.02	0.00	0.99	FALSE
16	GTEx	Artery Tibial	PMS2P5	0.21	0.08	lasso	5	0.07	1.9e-06	-4.7	6.7	2.1e-11	-0.71	0.02	0.97	FALSE
17	GTEx	Artery Tibial	POM121C	0.12	0.10	lasso	1	0.10	6.8e-08	5.3	5.3	1.4e-07	-0.05	0.01	0.99	FALSE
18	GTEx	Artery Tibial	STAG3L2	0.26	0.12	lasso	4	0.12	1.7e-09	-4.7	5.5	3.9e-08	-0.67	0.71	0.29	FALSE
19	GTEx	Artery Tibial	STAG3L1	0.25	0.19	lasso	4	0.19	8.3e-15	5.3	5.3	1.4e-07	-0.05	0.00	1.00	FALSE
20	GTEx	Brain Cerebellar Hemisphere	PMS2P5	0.40	0.07	enet	16	0.17	4.1e-05	-6.3	6.1	1.3e-09	-0.75	0.00	0.95	FALSE
21	GTEx	Brain Cerebellar Hemisphere	POM121C	0.33	0.32	lasso	3	0.30	1.4e-08	5.3	5.2	2.2e-07	-0.04	0.00	1.00	FALSE
22	GTEx	Brain Cerebellum	PMS2P5	0.62	0.08	lasso	6	0.22	3.3e-07	-4.7	5.9	3.6e-09	-0.74	0.01	0.95	FALSE
23	GTEx	Brain Cerebellum	POM121C	0.30	0.15	lasso	8	0.08	2.4e-03	5.3	5.3	9.2e-08	-0.02	0.01	0.88	TRUE
24	GTEx	Brain Frontal Cortex BA9	STAG3L2	0.28	0.07	lasso	4	0.11	9.7e-04	-6.3	6.1	8.5e-10	-0.89	0.00	0.93	FALSE
25	GTEx	Brain Nucleus accumbens basal ganglia	PMS2P5	0.27	0.00	enet	20	0.03	6.6e-02	-4.7	5.5	3.5e-08	-0.63	0.01	0.64	FALSE
26	GTEx	Breast Mammary Tissue	PMS2P3	0.19	0.14	lasso	4	0.19	3.5e-10	5.6	5.4	5.9e-08	-0.03	0.00	1.00	FALSE
27	GTEx	Breast Mammary Tissue	STAG3L2	0.14	0.08	lasso	2	0.11	4.0e-06	-4.7	5.8	7.8e-09	-0.80	0.02	0.97	FALSE
28	GTEx	Breast Mammary Tissue (Female)	STAG3L1	0.04	0.12	lasso	1	0.04	2.9e-02	5.3	5.3	1.4e-07	-0.05	0.00	0.89	FALSE
29	GTEx	Cells EBV-transformed lymphocytes	PMS2P5	0.16	0.06	lasso	3	0.04	1.7e-02	-6.3	6.4	1.5e-10	-0.89	0.01	0.87	FALSE
30	GTEx	Cells EBV-transformed lymphocytes	STAG3L2	0.33	0.04	lasso	12	0.08	1.0e-03	-3.3	5.8	8.6e-09	-0.72	0.01	0.82	FALSE
31	GTEx	Cells Transformed fibroblasts	PMS2P5	0.31	0.16	lasso	5	0.18	2.1e-13	-4.7	6.2	6.5e-10	-0.75	0.41	0.59	FALSE
32	GTEx	Cells Transformed fibroblasts	PMS2P3	0.23	0.15	lasso	6	0.15	1.4e-11	5.6	5.4	7.1e-08	-0.04	0.00	1.00	FALSE
33	GTEx	Cells Transformed fibroblasts	STAG3L2	0.18	0.16	lasso	5	0.16	7.5e-12	-4.7	5.4	5.9e-08	-0.71	0.78	0.22	FALSE
34	GTEx	Cells Transformed fibroblasts	STAG3L1	0.22	0.17	lasso	4	0.18	2.6e-13	5.3	5.2	1.9e-07	-0.04	0.01	0.99	FALSE
35	GTEx	Colon Transverse	STAG3L1	0.22	0.18	lasso	1	0.16	4.0e-08	5.3	5.3	1.4e-07	-0.05	0.01	0.99	FALSE
36	GTEx	Esophagus Gastroesophageal Junction	PMS2P5	0.23	0.19	lasso	2	0.18	5.4e-07	-6.3	7.1	1.5e-12	-0.97	0.00	1.00	FALSE
37	GTEx	Esophagus Gastroesophageal Junction	STAG3L1	0.36	0.16	lasso	5	0.16	1.7e-06	5.3	5.4	5.4e-08	-0.07	0.00	0.99	FALSE
38	GTEx	Esophagus Mucosa	PMS2P5	0.14	0.03	lasso	4	0.04	1.7e-03	-6.3	7.2	7.8e-13	-0.87	0.00	0.97	FALSE
39	GTEx	Esophagus Mucosa	PMS2P3	0.14	0.15	lasso	2	0.14	9.7e-10	5.3	5.3	1.2e-07	-0.05	0.00	1.00	TRUE
40	GTEx	Esophagus Mucosa	POM121C	0.13	0.10	lasso	1	0.07	1.0e-05	5.3	5.3	1.4e-07	-0.05	0.00	0.99	FALSE
41	GTEx	Esophagus Mucosa	STAG3L1	0.19	0.19	lasso	1	0.18	2.4e-12	5.3	5.3	1.4e-07	-0.05	0.01	0.99	FALSE
42	GTEx	Esophagus Muscularis	STAG3L2	0.23	0.09	enet	33	0.15	1.9e-09	-4.7	6.1	1.1e-09	-0.67	0.31	0.68	FALSE
43	GTEx	Esophagus Muscularis	TRIM73	0.12	0.07	lasso	2	0.05	3.5e-04	5.6	5.6	2.3e-08	-0.05	0.00	1.00	FALSE
44	GTEx	Esophagus Muscularis	STAG3L1	0.30	0.15	lasso	4	0.16	4.3e-10	5.3	5.8	5.0e-09	-0.07	0.01	0.99	FALSE
45	GTEx	Heart Atrial Appendage	PMS2P5	0.12	0.03	lasso	5	0.07	3.8e-04	-6.3	5.7	1.5e-08	-0.92	0.00	0.90	FALSE
46	GTEx	Heart Left Ventricle	PMS2P5	0.34	0.13	lasso	4	0.19	2.9e-10	-6.3	7.1	9.3e-13	-0.84	0.00	1.00	FALSE
47	GTEx	Heart Left Ventricle	POM121C	0.13	0.12	lasso	1	0.09	2.2e-05	5.3	5.3	1.4e-07	-0.05	0.00	0.99	FALSE
48	GTEx	Heart Left Ventricle	STAG3L2	0.20	0.12	lasso	3	0.09	1.9e-05	-4.7	5.2	2.6e-07	-0.60	0.12	0.73	FALSE
49	GTEx	Lung	POM121C	0.13	0.10	lasso	3	0.10	7.8e-08	5.3	5.5	3.8e-08	-0.05	0.00	1.00	FALSE
50	GTEx	Lung	STAG3L2	0.13	0.11	enet	11	0.09	1.4e-07	-4.7	6.0	2.3e-09	-0.77	0.08	0.92	FALSE
51	GTEx	Muscle Skeletal	PMS2P5	0.34	0.04	enet	22	0.14	1.6e-13	-4.7	6.9	5.0e-12	-0.61	0.00	1.00	FALSE
52	GTEx	Muscle Skeletal	PMS2P3	0.07	0.07	lasso	2	0.06	3.8e-06	5.3	5.2	2.4e-07	-0.05	0.00	0.99	FALSE
53	GTEx	Muscle Skeletal	STAG3L2	0.17	0.12	lasso	4	0.12	9.0e-12	-4.7	5.3	1.1e-07	-0.65	0.86	0.13	FALSE
54	GTEx	Muscle Skeletal	TRIM73	0.08	0.05	enet	11	0.06	3.4e-06	5.3	5.1	2.9e-07	-0.03	0.00	1.00	FALSE
55	GTEx	Nerve Tibial	PMS2P5	0.16	0.04	enet	34	0.08	3.5e-06	-4.7	6.2	8.0e-10	-0.60	0.05	0.90	FALSE
56	GTEx	Nerve Tibial	STAG3L2	0.36	0.09	enet	13	0.24	9.5e-17	-4.7	6.7	2.0e-11	-0.72	0.06	0.94	FALSE
57	GTEx	Nerve Tibial	GTF2IRD2	0.08	0.09	lasso	2	0.08	5.4e-06	-4.7	-5.3	1.1e-07	0.70	0.09	0.88	FALSE
58	GTEx	Skin Not Sun Exposed Suprapubic	PMS2P3	0.26	0.19	lasso	3	0.17	1.3e-09	5.3	5.2	1.9e-07	-0.03	0.00	1.00	FALSE
59	GTEx	Skin Not Sun Exposed Suprapubic	STAG3L1	0.13	0.19	lasso	1	0.18	2.6e-10	5.3	5.3	1.4e-07	-0.05	0.00	1.00	FALSE
60	GTEx	Skin Sun Exposed Lower leg	PMS2P3	0.38	0.30	lasso	3	0.29	1.9e-24	5.3	5.4	8.4e-08	-0.05	0.01	0.99	FALSE
61	GTEx	Skin Sun Exposed Lower leg	STAG3L2	0.15	0.05	enet	8	0.08	2.8e-07	-4.7	7.2	4.8e-13	-0.73	0.01	0.98	TRUE
62	GTEx	Stomach	PMS2P3	0.16	0.07	lasso	5	0.09	3.7e-05	5.3	5.5	3.5e-08	-0.03	0.00	1.00	FALSE
63	GTEx	Stomach	STAG3L1	0.35	0.20	lasso	5	0.18	4.2e-09	5.3	5.2	2.5e-07	-0.03	0.01	0.99	FALSE
64	GTEx	Testis	PMS2P5	0.22	0.13	lasso	2	0.13	3.1e-06	-6.3	6.4	2.1e-10	-0.99	0.00	1.00	FALSE
65	GTEx	Testis	STAG3L2	0.26	0.13	lasso	4	0.22	4.0e-10	-3.1	5.7	1.5e-08	-0.88	0.00	1.00	FALSE
66	GTEx	Testis	TRIM73	0.20	0.21	lasso	2	0.19	6.2e-09	5.3	5.2	1.7e-07	-0.04	0.01	0.99	FALSE
67	GTEx	Testis	STAG3L1	0.24	0.24	enet	14	0.27	1.4e-12	5.3	5.2	2.2e-07	-0.06	0.00	1.00	FALSE
68	GTEx	Thyroid	STAG3L2	0.26	0.13	enet	20	0.16	1.4e-12	-4.7	6.5	6.7e-11	-0.63	0.80	0.19	FALSE
69	METSIM	Adipose	NCF1	0.05	0.03	blup	130	0.04	3.9e-07	-4.6	-5.7	1.4e-08	0.59	0.04	0.96	FALSE
70	METSIM	Adipose	POM121C	0.11	0.08	lasso	1	0.08	1.6e-11	5.3	5.3	1.4e-07	-0.05	0.01	0.99	FALSE
71	METSIM	Adipose	TRIM73	0.11	0.11	lasso	5	0.12	8.6e-18	5.6	5.3	1.3e-07	-0.02	0.00	1.00	FALSE
72	ROSMAP	Brain Pre-frontal Cortex	PMS2P3	0.05	0.04	lasso	1	0.03	4.6e-05	5.3	5.3	1.4e-07	-0.05	0.00	1.00	FALSE
73	ROSMAP	Brain Pre-frontal Cortex	POM121C	0.36	0.26	lasso	7	0.27	2.8e-34	5.3	5.3	1.3e-07	-0.05	0.00	1.00	FALSE
74	ROSMAP	Brain Pre-frontal Cortex	PMS2P2	0.17	0.08	enet	8	0.08	6.0e-10	5.3	5.3	1.5e-07	-0.02	0.00	1.00	FALSE
75	ROSMAP	Brain Pre-frontal Cortex	STAG3L1	0.46	0.32	lasso	4	0.32	2.2e-42	5.3	5.3	1.4e-07	-0.05	0.00	1.00	FALSE
76	ROSMAP	Brain Pre-frontal Cortex	GTF2IP1	0.09	0.06	lasso	3	0.05	1.7e-07	5.3	5.2	1.6e-07	-0.05	0.16	0.82	FALSE
77	The Cancer Genome Atlas	Breast Invasive Carcinoma	POM121C	0.04	0.04	lasso	2	0.03	1.2e-07	5.3	5.2	1.6e-07	-0.05	0.00	1.00	FALSE
78	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	PMS2L3	0.23	0.14	lasso	2	0.14	1.3e-04	5.3	5.4	6.2e-08	-0.06	0.00	0.87	FALSE