[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr2:69,678,079-71,228,388

Best TWAS P=6.48e-12 · Best GWAS P=6.92e-10 conditioned to 0.00152

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes FAM136A 0.31 0.12 lasso 7 0.16 5.6e-06 5.7 6.9 6.5e-12 -0.50 0.06 0.92 TRUE
2 GTEx Cells Transformed fibroblasts FAM136A 0.22 0.17 lasso 5 0.14 6.2e-11 -5.4 5.4 7.1e-08 -0.76 0.09 0.91 FALSE
3 GTEx Cells Transformed fibroblasts C2orf42 0.18 0.05 enet 28 0.14 1.3e-10 -5.0 5.6 2.7e-08 -0.69 0.19 0.81 FALSE
4 GTEx Colon Transverse PCYOX1 0.13 0.01 lasso 3 0.00 2.7e-01 -6.2 -5.6 2.2e-08 0.94 0.01 0.96 FALSE
5 GTEx Heart Left Ventricle FAM136A 0.17 0.09 enet 22 0.09 2.0e-05 -5.3 5.2 2.1e-07 -0.73 0.09 0.90 FALSE
6 ROSMAP Brain Pre-frontal Cortex FAM136A 0.09 0.08 lasso 3 0.06 9.9e-09 -5.0 5.2 1.8e-07 -0.85 0.13 0.87 FALSE
7 ROSMAP Brain Pre-frontal Cortex SNRPG 0.03 0.01 blup 225 0.02 2.7e-03 5.7 5.9 3.1e-09 -0.71 0.05 0.82 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma FAM136A 0.03 0.04 lasso 2 0.03 1.3e-07 -5.4 5.4 6.7e-08 -0.75 0.00 1.00 FALSE
9 The Cancer Genome Atlas Colon Adenocarcinoma FAM136A 0.10 0.12 lasso 2 0.12 3.0e-07 -5.4 5.4 6.4e-08 -0.75 0.00 1.00 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma FAM136A 0.02 0.01 blup 42 0.01 2.1e-02 -5.4 5.2 2.2e-07 -0.63 0.01 0.64 FALSE
11 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma FAM136A 0.06 0.01 enet 5 0.00 1.7e-01 -5.4 5.4 5.5e-08 -0.66 0.01 0.78 FALSE
12 The Cancer Genome Atlas Soft Tissue Sarcoma C2orf42 0.12 0.03 enet 17 0.05 1.0e-03 -5.4 6.1 1.0e-09 -0.61 0.01 0.84 FALSE
13 The Cancer Genome Atlas Soft Tissue Sarcoma FAM136A 0.08 0.02 enet 4 0.03 8.7e-03 3.1 5.2 1.9e-07 -0.70 0.01 0.77 FALSE