[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr2:69,678,079-71,228,388

Best TWAS P=6.48e-12 · Best GWAS P=6.92e-10 conditioned to 0.00152

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Cells EBV-transformed lymphocytes	FAM136A	0.31	0.12	lasso	7	0.16	5.6e-06	5.7	6.9	6.5e-12	-0.50	0.06	0.92	TRUE
12	The Cancer Genome Atlas	Soft Tissue Sarcoma	C2orf42	0.12	0.03	enet	17	0.05	1.0e-03	-5.4	6.1	1.0e-09	-0.61	0.01	0.84	FALSE
7	ROSMAP	Brain Pre-frontal Cortex	SNRPG	0.03	0.01	blup	225	0.02	2.7e-03	5.7	5.9	3.1e-09	-0.71	0.05	0.82	FALSE
4	GTEx	Colon Transverse	PCYOX1	0.13	0.01	lasso	3	0.00	2.7e-01	-6.2	-5.6	2.2e-08	0.94	0.01	0.96	FALSE
3	GTEx	Cells Transformed fibroblasts	C2orf42	0.18	0.05	enet	28	0.14	1.3e-10	-5.0	5.6	2.7e-08	-0.69	0.19	0.81	FALSE
11	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FAM136A	0.06	0.01	enet	5	0.00	1.7e-01	-5.4	5.4	5.5e-08	-0.66	0.01	0.78	FALSE
9	The Cancer Genome Atlas	Colon Adenocarcinoma	FAM136A	0.10	0.12	lasso	2	0.12	3.0e-07	-5.4	5.4	6.4e-08	-0.75	0.00	1.00	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	FAM136A	0.03	0.04	lasso	2	0.03	1.3e-07	-5.4	5.4	6.7e-08	-0.75	0.00	1.00	FALSE
2	GTEx	Cells Transformed fibroblasts	FAM136A	0.22	0.17	lasso	5	0.14	6.2e-11	-5.4	5.4	7.1e-08	-0.76	0.09	0.91	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	FAM136A	0.09	0.08	lasso	3	0.06	9.9e-09	-5.0	5.2	1.8e-07	-0.85	0.13	0.87	FALSE
13	The Cancer Genome Atlas	Soft Tissue Sarcoma	FAM136A	0.08	0.02	enet	4	0.03	8.7e-03	3.1	5.2	1.9e-07	-0.70	0.01	0.77	FALSE
5	GTEx	Heart Left Ventricle	FAM136A	0.17	0.09	enet	22	0.09	2.0e-05	-5.3	5.2	2.1e-07	-0.73	0.09	0.90	FALSE
10	The Cancer Genome Atlas	Brain Lower Grade Glioma	FAM136A	0.02	0.01	blup	42	0.01	2.1e-02	-5.4	5.2	2.2e-07	-0.63	0.01	0.64	FALSE