Best TWAS P=8.28e-08 · Best GWAS P=5.64e-07 conditioned to 0.78
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | SERPINF1 | 0.19 | 0.05 | lasso | 6 | 0.02 | 6.3e-03 | 5 | -5.1 | 3.1e-07 | -0.96 | 0.00 | 0.96 | FALSE |
| 2 | GTEx | Brain Cortex | SMYD4 | 0.34 | 0.17 | lasso | 4 | 0.23 | 5.3e-07 | 4 | -5.1 | 2.7e-07 | -0.80 | 0.03 | 0.66 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | SERPINF1 | 0.20 | 0.11 | lasso | 3 | 0.16 | 5.6e-12 | 5 | -5.4 | 8.3e-08 | -0.91 | 0.00 | 1.00 | TRUE |