[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr17:27,200,734-28,952,286

Best TWAS P=5.01e-10 · Best GWAS P=2.65e-09 conditioned to 0.225

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Nucleus accumbens basal ganglia	CORO6	0.11	0.10	lasso	2	0.05	2.2e-02	5.9	-5.6	2.0e-08	-0.87	0.08	0.69	FALSE
2	GTEx	Esophagus Muscularis	SSH2	0.04	0.01	enet	10	0.00	3.3e-01	5.5	5.8	6.1e-09	0.84	0.09	0.84	FALSE
3	GTEx	Lung	SSH2	0.08	0.05	lasso	6	0.06	2.7e-05	5.5	5.5	4.9e-08	0.89	0.22	0.78	FALSE
4	GTEx	Lung	ANKRD13B	0.13	0.09	lasso	6	0.08	6.8e-07	-4.8	-5.6	2.5e-08	-0.66	0.29	0.70	FALSE
5	GTEx	Nerve Tibial	SSH2	0.05	0.06	lasso	10	0.06	7.8e-05	5.5	5.7	1.6e-08	0.99	0.09	0.90	FALSE
6	GTEx	Thyroid	GIT1	0.06	0.08	lasso	5	0.09	3.7e-07	-5.3	5.7	1.2e-08	0.88	0.08	0.92	FALSE
7	GTEx	Thyroid	SSH2	0.12	0.17	enet	10	0.18	2.0e-13	-5.6	5.8	8.6e-09	0.84	0.12	0.88	FALSE
8	GTEx	Thyroid	TP53I13	0.14	0.16	enet	7	0.14	6.0e-11	-4.1	5.4	5.4e-08	0.63	0.98	0.02	FALSE
9	GTEx	Thyroid	CORO6	0.23	0.36	lasso	5	0.37	1.2e-29	-5.6	5.7	1.2e-08	0.82	0.14	0.86	FALSE
10	METSIM	Adipose	ANKRD13B	0.04	0.03	lasso	3	0.05	1.4e-07	5.9	-6.2	5.0e-10	-0.86	0.07	0.93	TRUE
11	METSIM	Adipose	CORO6	0.02	0.02	bslmm	314	0.01	1.7e-02	5.9	-5.8	4.9e-09	-0.87	0.09	0.76	FALSE
12	METSIM	Adipose	SSH2	0.03	0.03	blup	422	0.02	1.5e-04	-5.6	5.3	1.2e-07	0.92	0.08	0.92	FALSE
13	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	EFCAB5	0.06	0.08	lasso	2	0.07	1.4e-06	5.7	5.8	9.2e-09	0.84	0.04	0.95	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	EFCAB5	0.02	0.04	lasso	4	0.04	1.9e-08	5.4	5.5	4.0e-08	0.94	0.06	0.94	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	SSH2	0.01	0.01	blup	111	0.01	1.0e-03	-5.7	5.8	4.9e-09	0.98	0.05	0.93	FALSE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	CCDC55	0.15	0.01	blup	64	0.04	1.9e-03	5.4	-5.5	3.5e-08	-0.77	0.02	0.56	FALSE
17	The Cancer Genome Atlas	Colon Adenocarcinoma	EFCAB5	0.06	0.05	blup	79	0.03	5.7e-03	5.4	5.4	6.9e-08	0.91	0.05	0.91	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EFCAB5	0.09	0.12	lasso	5	0.12	3.1e-13	5.5	5.4	5.6e-08	0.91	0.06	0.94	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SSH2	0.03	0.02	blup	112	0.03	2.4e-04	5.9	5.8	4.8e-09	0.98	0.04	0.95	FALSE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	EFCAB5	0.07	0.09	enet	16	0.08	4.0e-09	5.5	5.4	8.4e-08	0.86	0.06	0.94	FALSE
21	The Cancer Genome Atlas	Lung Adenocarcinoma	EFCAB5	0.06	0.09	lasso	1	0.09	2.9e-10	5.5	5.5	3.1e-08	0.99	0.05	0.95	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	SSH2	0.06	0.03	blup	112	0.05	2.5e-06	-5.6	5.9	3.6e-09	0.95	0.06	0.94	FALSE
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EFCAB5	0.04	0.04	lasso	4	0.05	5.9e-06	5.5	5.5	5.1e-08	0.91	0.06	0.94	FALSE
24	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	EFCAB5	0.08	0.01	blup	79	0.03	1.7e-02	5.4	5.5	3.1e-08	0.92	0.04	0.64	FALSE
25	The Cancer Genome Atlas	Soft Tissue Sarcoma	EFCAB5	0.06	0.07	lasso	2	0.05	8.2e-04	5.4	5.6	1.9e-08	0.91	0.05	0.93	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	ANKRD13B	0.14	0.20	lasso	4	0.19	2.2e-18	-5.6	5.5	3.1e-08	0.82	0.02	0.98	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	CORO6	0.28	0.40	lasso	3	0.39	6.2e-40	-5.6	5.5	2.9e-08	0.82	0.02	0.98	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	EFCAB5	0.11	0.18	enet	13	0.20	5.8e-19	5.4	5.5	4.1e-08	0.95	0.06	0.94	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	SSH2	0.25	0.18	lasso	5	0.17	4.8e-16	-5.6	5.6	2.1e-08	0.85	0.14	0.86	FALSE