[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr17:78,665,405-80,866,427

Best TWAS P=1.32e-16 · Best GWAS P=1.82e-12 conditioned to 9.76e-05

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
31	The Cancer Genome Atlas	Thyroid Carcinoma	DCXR	0.09	0.03	blup	38	0.09	9.5e-09	5.8	8.3	1.3e-16	-0.41	0.02	0.98	TRUE
11	GTEx	Brain Cerebellum	RP11-1055B8.4	0.25	0.27	lasso	2	0.27	1.3e-08	5.6	-5.7	1.4e-08	0.02	0.00	1.00	TRUE
1	CommonMind	Brain Pre-frontal Cortex	DCXR	0.14	0.07	enet	17	0.10	3.4e-12	5.2	7.8	6.4e-15	-0.43	0.10	0.90	FALSE
22	YFS	Blood	ASPSCR1	0.11	0.07	lasso	9	0.06	7.9e-20	-6.8	7.3	2.5e-13	-0.69	0.00	1.00	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	DCXR	0.12	0.00	enet	13	0.00	2.3e-01	5.8	7.2	4.1e-13	-0.44	0.07	0.32	FALSE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PYCR1	0.02	0.01	blup	9	0.01	1.1e-02	-7.0	7.2	4.2e-13	-0.94	0.00	0.74	FALSE
27	The Cancer Genome Atlas	Brain Lower Grade Glioma	NOTUM	0.06	0.02	enet	2	0.02	4.7e-03	-6.5	-7.2	5.7e-13	0.92	0.01	0.53	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MYADML2	0.52	0.43	enet	15	0.45	3.6e-60	-7.0	-7.1	9.6e-13	0.97	0.00	1.00	FALSE
26	The Cancer Genome Atlas	Brain Lower Grade Glioma	MYADML2	0.03	0.03	blup	10	0.03	1.1e-04	-6.9	-7.0	2.5e-12	0.93	0.01	0.96	FALSE
14	GTEx	Esophagus Muscularis	DCXR	0.18	0.08	lasso	5	0.05	9.2e-04	5.8	6.9	6.7e-12	-0.30	0.19	0.74	FALSE
21	GTEx	Thyroid	DCXR	0.35	0.20	lasso	5	0.30	5.1e-23	5.8	6.8	1.3e-11	-0.22	0.81	0.19	FALSE
20	GTEx	Thyroid	ASPSCR1	0.23	0.15	enet	19	0.09	1.2e-07	-5.9	6.6	4.1e-11	-0.69	0.68	0.32	FALSE
18	GTEx	Skin Sun Exposed Lower leg	DCXR	0.08	0.11	lasso	7	0.09	4.6e-08	5.8	6.6	5.2e-11	-0.22	0.61	0.39	FALSE
15	GTEx	Heart Atrial Appendage	LRRC45	0.19	0.06	enet	9	0.12	6.7e-06	-6.1	6.5	9.3e-11	-0.82	0.02	0.98	FALSE
4	GTEx	Adipose Subcutaneous	LRRC45	0.23	0.06	lasso	3	0.05	1.0e-04	-5.6	6.4	2.0e-10	-0.56	0.74	0.13	FALSE
16	GTEx	Nerve Tibial	DCXR	0.19	0.06	enet	20	0.10	1.4e-07	5.2	6.3	2.4e-10	-0.26	0.17	0.81	FALSE
8	GTEx	Artery Tibial	DCXR	0.28	0.21	lasso	5	0.21	3.1e-16	5.8	6.3	3.2e-10	-0.23	0.78	0.22	FALSE
6	GTEx	Artery Aorta	DCXR	0.34	0.17	enet	25	0.21	1.4e-11	5.8	6.1	1.2e-09	-0.29	0.81	0.19	FALSE
10	GTEx	Brain Cerebellum	DCXR	0.20	0.23	lasso	3	0.22	4.5e-07	5.8	6.1	1.3e-09	-0.22	0.26	0.26	FALSE
7	GTEx	Artery Tibial	LRRC45	0.09	0.07	lasso	4	0.04	2.0e-04	-5.6	6.0	1.9e-09	-0.68	0.04	0.95	FALSE
24	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LRRC45	0.02	0.03	blup	36	0.02	1.5e-03	-5.5	5.9	3.5e-09	-0.55	0.03	0.50	FALSE
23	YFS	Blood	LRRC45	0.01	0.00	lasso	1	0.00	1.3e-02	5.8	5.8	6.0e-09	-0.22	0.03	0.24	FALSE
28	The Cancer Genome Atlas	Lung Adenocarcinoma	NPB	0.03	0.01	enet	3	0.01	1.1e-02	-6.1	5.8	8.2e-09	-0.82	0.01	0.53	FALSE
5	GTEx	Adrenal Gland	DCXR	0.38	0.18	lasso	4	0.20	1.2e-07	5.8	5.7	1.5e-08	-0.26	0.52	0.40	FALSE
9	GTEx	Artery Tibial	CCDC57	0.08	0.03	enet	7	0.05	5.8e-05	-3.9	5.6	1.9e-08	-0.21	0.67	0.10	FALSE
19	GTEx	Skin Sun Exposed Lower leg	RP11-1055B8.4	0.21	0.10	lasso	3	0.10	7.4e-09	5.6	-5.6	2.4e-08	0.02	0.00	1.00	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	STRA13	0.05	0.03	lasso	3	0.02	1.8e-03	-5.5	5.5	3.3e-08	-0.54	0.08	0.47	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	DCXR	0.29	0.24	lasso	2	0.20	3.8e-07	5.2	5.4	5.3e-08	-0.21	0.49	0.42	FALSE
13	GTEx	Cells Transformed fibroblasts	LRRC45	0.08	0.08	enet	3	0.08	2.6e-06	-5.6	5.4	6.1e-08	-0.54	0.78	0.21	FALSE
3	CommonMind	Brain Pre-frontal Cortex	RAC3	0.09	0.05	enet	10	0.07	2.2e-08	6.6	5.4	7.4e-08	-0.16	0.03	0.96	FALSE
29	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LRRC45	0.10	0.02	blup	35	0.04	8.0e-03	-4.0	5.3	1.3e-07	-0.45	0.01	0.28	FALSE