[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr2:231,628,878-233,349,588

Best TWAS P=2.56e-10 · Best GWAS P=1.71e-09 conditioned to 0.0347

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	The Cancer Genome Atlas	Colon Adenocarcinoma	C2orf52	0.21	0.16	blup	42	0.24	7.1e-14	-5.3	6.3	2.6e-10	-0.74	0.06	0.94	TRUE
1	GTEx	Artery Coronary	RP11-690I21.1	0.24	-0.01	lasso	8	-0.01	6.8e-01	-4.9	5.3	8.6e-08	0.01	0.07	0.14	TRUE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	C2orf52	0.18	0.16	enet	12	0.19	3.0e-21	-5.5	6.3	2.6e-10	-0.51	0.08	0.92	FALSE
11	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C2orf52	0.23	0.25	enet	12	0.28	2.9e-32	-5.6	6.2	7.2e-10	-0.61	0.03	0.97	FALSE
9	The Cancer Genome Atlas	Glioblastoma Multiforme	C2orf52	0.28	0.12	enet	12	0.18	5.0e-06	-5.5	6.2	7.4e-10	-0.71	0.03	0.88	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	C2orf52	0.32	0.25	blup	42	0.31	1.5e-35	-5.6	6.0	1.5e-09	-0.49	0.03	0.97	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	C2orf52	0.32	0.34	blup	42	0.39	9.3e-44	-5.3	6.0	1.5e-09	-0.64	0.09	0.91	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C2orf52	0.18	0.16	blup	42	0.17	9.8e-19	-5.6	6.0	2.7e-09	-0.56	0.03	0.97	FALSE
3	ROSMAP	Brain Pre-frontal Cortex	LINC00471	0.34	0.26	lasso	10	0.36	2.1e-48	-5.3	5.9	3.9e-09	-0.57	0.10	0.90	FALSE
4	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C2orf52	0.15	0.14	enet	8	0.13	3.7e-11	-5.5	5.9	4.0e-09	-0.67	0.07	0.93	FALSE
25	The Cancer Genome Atlas	Thyroid Carcinoma	C2orf52	0.45	0.31	enet	10	0.35	4.9e-35	-5.3	5.9	4.7e-09	-0.57	0.09	0.91	FALSE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	C2orf52	0.19	0.22	blup	42	0.25	4.1e-50	-5.3	5.8	8.2e-09	-0.59	0.08	0.92	FALSE
19	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C2orf52	0.27	0.27	lasso	5	0.28	1.7e-11	-5.5	5.8	8.6e-09	-0.67	0.07	0.93	FALSE
23	The Cancer Genome Atlas	Stomach Adenocarcinoma	C2orf52	0.12	0.10	enet	11	0.12	5.6e-09	-5.3	5.7	1.2e-08	-0.67	0.07	0.93	FALSE
8	The Cancer Genome Atlas	Esophageal Carcinoma	C2orf52	0.16	0.03	enet	6	0.10	3.3e-04	-3.8	5.6	1.9e-08	-0.58	0.04	0.55	FALSE
21	The Cancer Genome Atlas	Soft Tissue Sarcoma	C2orf52	0.33	0.16	blup	42	0.21	2.0e-12	-5.6	5.5	3.3e-08	-0.36	0.04	0.96	FALSE
6	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C2orf52	0.28	0.12	lasso	6	0.12	2.0e-06	-5.2	5.5	3.5e-08	-0.75	0.04	0.96	FALSE
14	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C2orf52	0.13	0.06	lasso	4	0.05	2.1e-03	-5.5	5.4	6.2e-08	-0.61	0.03	0.53	FALSE
2	ROSMAP	Brain Pre-frontal Cortex	NCL	0.16	0.05	lasso	6	0.08	6.1e-10	3.0	5.4	7.3e-08	-0.83	0.01	0.99	FALSE
16	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C2orf52	0.28	0.18	lasso	4	0.20	3.7e-22	-5.2	5.4	7.7e-08	-0.59	0.08	0.92	FALSE
18	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C2orf52	0.32	0.21	lasso	7	0.21	3.6e-09	-5.3	5.4	7.7e-08	-0.61	0.06	0.94	FALSE
12	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C2orf52	0.18	0.20	lasso	3	0.19	3.4e-11	-5.3	5.3	1.0e-07	-0.63	0.08	0.92	FALSE
17	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C2orf52	0.24	0.20	lasso	3	0.20	1.4e-13	-5.3	5.3	1.3e-07	-0.62	0.08	0.92	FALSE
22	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C2orf52	0.21	0.20	lasso	1	0.18	1.4e-05	-5.2	5.2	2.5e-07	-0.62	0.03	0.62	FALSE
24	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C2orf52	0.29	0.17	enet	10	0.19	3.2e-07	-5.5	5.2	2.6e-07	-0.47	0.07	0.89	FALSE