TWAS hub - FILIP1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0310	0.0180	1.4e-02	0.010	0.016	0.009	0.017	0.004	2.0e-02	4.4e-03	2.7e-02	3.2e-03	8.5e-02
2	GTEx	Adipose Subcutaneous	0.0750	0.0290	3.4e-05	0.056	NA	0.043	NA	0.050	2.2e-05	NA	1.9e-04	NA	6.3e-05
3	GTEx	Brain Cerebellar Hemisphere	0.2820	0.0750	2.2e-07	0.218	NA	0.243	NA	0.276	2.8e-06	NA	6.4e-07	NA	8.8e-08
4	GTEx	Brain Cerebellum	0.1100	0.0540	9.1e-03	0.195	NA	0.050	NA	0.169	2.0e-06	NA	1.4e-02	NA	1.1e-05
5	GTEx	Cells Transformed fibroblasts	0.3150	0.0520	0.0e+00	0.404	NA	0.400	NA	0.405	2.7e-32	NA	7.2e-32	NA	2.0e-32
6	GTEx	Esophagus Muscularis	0.0890	0.0420	3.1e-03	0.001	NA	0.004	NA	0.007	2.9e-01	NA	1.8e-01	NA	1.1e-01
7	GTEx	Muscle Skeletal	0.0449	0.0202	3.0e-03	0.000	NA	0.013	NA	0.002	2.8e-01	NA	1.6e-02	NA	2.0e-01
8	METSIM	Adipose	0.0313	0.0160	3.6e-03	0.020	0.008	0.011	0.006	0.015	4.8e-04	2.1e-02	6.9e-03	3.3e-02	2.2e-03
9	ROSMAP	Brain Pre-frontal Cortex	0.0465	0.0175	1.8e-05	0.043	0.038	0.040	0.037	0.045	2.7e-06	1.1e-05	6.6e-06	1.4e-05	1.8e-06
10	TCGA	Glioblastoma Multiforme	0.1720	0.0950	1.9e-03	0.004	0.047	-0.010	NA	-0.006	2.3e-01	1.5e-02	9.6e-01	NA	5.3e-01
11	TCGA	Brain Lower Grade Glioma	0.1387	0.0407	0.0e+00	0.258	0.274	0.296	NA	0.282	3.7e-29	4.2e-31	6.2e-34	NA	4.0e-32
12	TCGA	Skin Cutaneous Melanoma	0.3380	0.1140	1.2e-03	0.034	0.155	0.130	NA	0.117	4.2e-02	6.2e-05	2.5e-04	NA	5.1e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12
Forced vital capacity (FVC)	7.0	26.8	40.8	-5.4	-5.9	-6.4	-5.2	-5.7	-4.5	-4.0	-5.5	5.4	-5.4	-5.6	-0.9
Qualifications: O levels/GCSEs or equivalent	7.0	11.2	16.3	-2.8	-3.3	-3.8	-4.0	-3.7	-3.2	-2.8	-2.8	3.9	-3.9	-3.9	0.2
Forced expiratory volume in 1-second (FEV1)	6.0	20.1	28.2	-4.5	-5.0	-5.3	-4.7	-4.9	-4.0	-3.1	-4.9	4.9	-4.8	-4.9	-0.8
Multivitamins +/- minerals	5.3	6.7	10.4	-3.2	-1.9	-2.5	-3.0	-2.0	-2.2	-2.4	-2.5	3.1	-3.0	-3.2	1.6
Hearing difficulty/problems: Yes	5.1	7.7	12.2	3.3	2.5	3.0	2.9	2.5	2.9	1.6	3.3	-3.0	2.9	3.5	-0.9
Forced vital capacity (FVC), Best measure	4.9	17.8	27.2	-4.7	-5.0	-5.2	-4.3	-4.7	-3.0	-3.0	-4.5	4.4	-4.2	-4.6	-1.0
Leg pain on walking	4.9	6.1	11.0	-1.5	-2.5	-3.0	-2.7	-2.7	-1.5	-1.9	-2.8	2.8	-3.3	-3.0	0.7
Noisy workplace	4.8	5.9	8.8	2.1	1.4	2.9	3.0	2.0	1.8	2.9	2.6	-2.3	2.9	2.7	-1.9
Breast cancer (self-reported)	4.3	5.1	7.7	-2.7	-1.8	-2.4	-2.5	-1.6	-1.8	-2.0	-2.0	2.3	-2.6	-2.8	2.2
Forced expiratory volume in 1-second (FEV1), Best measure	4.2	13.4	19.4	-3.6	-4.3	-4.4	-3.9	-4.2	-2.8	-2.3	-4.1	4.0	-3.8	-4.0	-1.1
Forced expiratory volume in 1-second (FEV1), predicted	4.2	8.7	13.0	-2.7	-3.3	-3.6	-2.8	-3.2	-1.7	-3.6	-3.1	3.0	-3.0	-3.5	0.9
Hand grip strength (right)	4.1	11.1	15.9	-3.7	-3.8	-3.8	-3.4	-3.9	-2.5	-0.6	-3.8	4.0	-3.3	-3.6	-2.0
Supplements: Fish oil (including cod liver oil)	4.0	5.2	14.7	-3.8	-2.1	-2.5	-2.3	-2.0	-1.3	-1.8	-2.4	2.2	-2.4	-2.5	0.3
Medication: Co-codamol	3.8	4.4	8.0	-1.3	-1.7	-2.1	-2.7	-2.0	-1.8	-1.6	-2.8	2.1	-2.8	-2.5	1.1
Illnesses of siblings: Diabetes	3.7	4.6	7.4	-1.1	-2.2	-2.2	-2.5	-2.5	-1.6	-2.7	-2.0	2.2	-2.5	-2.6	0.2
Relative age voice broke	3.6	5.5	9.3	-3.1	-2.1	-2.7	-2.9	-2.2	-1.6	-0.5	-2.7	2.6	-2.8	-2.7	0.4
Mineral and other dietary supplements	3.5	4.8	7.9	2.8	2.2	2.7	2.3	2.3	1.6	1.2	2.4	-2.1	2.4	2.5	0.6
Pain experienced in last month	3.5	5.9	9.8	1.1	2.4	2.6	3.1	2.6	2.1	1.8	3.0	-2.7	2.9	2.8	-0.3
Ulcerative Colitis (UC)	3.2	5.9	8.7	-2.1	-2.9	-2.9	-2.7	-2.7	-2.8	-1.2	-2.2	2.7	-2.6	-2.6	-0.4
Qualifications: nursing, teaching	3.2	4.9	9.8	-2.0	-2.5	-3.1	-2.3	-2.3	-1.7	-2.8	-1.7	2.2	-2.0	-2.5	-0.1
Back pain experienced in last month	3.1	4.5	8.2	-1.6	-2.1	-1.9	-2.5	-2.1	-0.7	-0.6	-2.8	2.7	-2.9	-2.7	1.2
Rheumatoid Arthritis	2.9	3.9	7.2	1.2	2.5	2.2	2.2	2.7	0.0	-0.3	2.5	-2.0	2.7	2.1	0.7
Fluid intelligence score	2.9	5.9	10.1	-3.0	-2.8	-3.2	-2.1	-2.4	-2.1	-2.3	-2.1	2.3	-2.7	-2.7	0.8
Pain all over the body in last month	2.8	3.0	8.9	-1.4	-0.8	-2.0	-2.2	-1.1	0.6	-1.4	-3.0	1.4	-2.0	-1.9	1.4
Wheeze or whistling in the chest in last year	2.8	5.1	11.0	3.3	1.5	2.3	2.7	1.8	1.4	1.6	2.7	-2.2	2.4	2.7	-1.2
Intelligence (Savage-Jansen 2018)	2.7	8.3	16.0	-3.3	-3.2	-3.7	-2.6	-3.2	-2.3	-4.0	-2.4	2.4	-2.5	-3.0	0.3
Falls in the last year	2.7	3.7	8.5	1.3	2.1	2.4	1.4	2.3	2.3	2.9	0.8	-1.4	1.4	1.5	2.1
Medication: Ibuprofen (e.g. Nurofen)	2.7	3.4	7.0	2.4	1.9	2.6	1.8	2.1	0.4	1.0	2.3	-1.8	1.9	2.1	0.2
Peak expiratory flow (PEF)	2.7	6.3	9.0	-2.4	-2.5	-2.8	-2.8	-2.6	-1.8	-2.6	-2.4	3.0	-2.5	-3.0	-0.6
Average weekly red wine intake	2.6	3.8	10.1	-3.2	-1.1	-2.1	-2.1	-1.4	-1.3	0.5	-2.2	2.0	-2.2	-2.2	1.8
Headache pain in last month	2.5	4.3	6.6	-0.4	-2.5	-2.2	-2.6	-2.5	-2.0	-1.1	-2.2	2.4	-2.5	-2.4	0.1
Hearing aid user	2.5	2.8	4.5	1.6	1.7	2.1	1.6	1.8	1.9	2.0	1.8	-1.5	1.4	1.7	0.5
Systolic blood pressure, automated reading	2.4	7.0	10.7	3.3	2.4	3.2	2.8	2.5	2.6	2.0	2.7	-2.4	3.2	2.9	-1.2
Smoking status: Previous	2.4	3.6	4.5	-1.8	-2.1	-1.9	-1.9	-2.0	-2.0	1.6	-1.7	2.1	-1.9	-2.0	-1.5
Ever had prostate specific antigen (PSA) test	2.4	2.7	4.2	-2.0	-1.3	-1.9	-2.0	-1.4	-1.0	-0.5	-1.9	1.9	-1.9	-1.9	1.2
Ulcerative Colitis	2.3	3.4	5.8	-1.3	-2.4	-2.2	-2.3	-2.0	0.0	-1.4	-1.9	2.3	-2.1	-2.1	-0.2
Relative age of first facial hair	2.3	4.8	7.5	-2.6	-1.9	-2.4	-2.6	-2.0	-1.5	-1.1	-2.7	2.5	-2.5	-2.6	0.4
Medication for cholesterol	2.3	3.5	7.3	-2.7	-2.4	-2.7	-1.3	-2.0	-1.8	-1.8	-1.7	1.4	-1.7	-1.6	-0.1
Alzheimer’s Disease (including proxy)	2.2	3.1	5.5	1.9	1.4	1.9	2.3	1.4	1.6	1.1	1.3	-2.1	2.3	2.0	-1.4
Lung FVC	2.2	11.1	21.9	-2.7	-4.7	-3.9	-3.6	-4.0	-3.0	0.5	-3.0	3.6	-3.5	-3.1	-2.6
Diverticular disease/diverticulitis (self-reported)	2.2	2.6	4.5	0.6	1.8	1.7	1.9	1.9	1.3	-1.1	1.6	-2.0	2.1	1.8	0.8
Length of working week for main job	2.2	2.5	4.9	1.4	0.9	1.8	1.6	1.0	0.1	2.1	1.5	-1.4	1.9	1.7	-2.2
Qualifications: College or University degree	2.2	6.9	11.8	-2.9	-3.0	-3.4	-2.5	-3.1	-2.5	-1.4	-2.5	2.6	-2.9	-2.8	-0.9
Commuting to job workplace: Cycle	2.2	2.7	4.9	-1.3	-2.2	-2.1	-1.1	-2.0	-2.2	-0.9	-1.9	1.4	-1.5	-1.3	-1.0
Verbal and Numeric Reasoning (VNR)	2.1	5.1	9.3	-2.5	-2.7	-3.0	-2.1	-2.6	-2.0	-1.7	-2.1	2.2	-2.3	-2.4	-0.3
Hand grip strength (left)	2.1	5.6	9.1	-3.0	-3.0	-2.9	-2.1	-2.7	-1.3	-1.3	-2.5	2.7	-2.2	-2.5	-1.1
Alzheimer’s Disease (in mother)	2.0	2.3	3.5	1.9	1.1	1.6	1.8	1.2	1.7	1.4	0.9	-1.7	1.8	1.7	-1.0
Vitamin and mineral supplements	2.0	2.8	5.9	1.6	1.2	1.7	2.0	1.5	2.4	1.2	1.6	-2.1	1.5	1.9	0.4
Past tobacco smoking	2.0	3.7	4.9	1.7	2.1	1.9	1.8	2.1	1.6	-2.0	1.8	-2.0	1.7	1.9	2.2
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	3.4	-1.2	-1.2	-1.4	-1.8	-1.3	-1.8	-1.8	-1.0	1.7	-1.8	-1.8	1.1
Ever had stillbirth, spontaneous miscarriage or termination	2.0	2.1	4.7	-1.5	-0.8	-1.7	-1.7	-1.3	-0.4	0.3	-2.0	1.4	-2.2	-1.7	1.1
Ever smoked	2.0	3.5	4.7	-2.0	-1.9	-1.9	-1.9	-2.1	-1.3	1.5	-2.0	2.2	-1.7	-2.0	-1.8
Worry (Nagel 2018)	1.9	4.1	6.5	0.7	2.1	2.5	2.5	2.2	2.0	1.7	2.1	-2.0	2.4	2.3	-0.7
HbA1C	1.9	2.1	12.4	-0.8	-1.4	-1.4	-0.5	-1.5	1.8	-0.9	-0.5	0.6	0.3	-0.7	-3.5
Supplements: Glucosamine	1.8	2.4	4.1	-1.9	-1.5	-2.0	-1.5	-1.6	-0.7	0.2	-2.0	1.6	-1.8	-1.8	0.1
Chronic bronchitis/emphysema (father)	1.8	2.1	3.9	-0.5	-1.9	-2.0	-1.8	-1.6	-1.7	-0.5	-1.4	1.3	-1.6	-1.3	0.5
Qualifications: None of the above	1.8	3.8	8.1	2.2	2.2	2.4	1.8	2.0	1.8	2.8	0.9	-1.8	1.4	2.0	1.0
Financial difficulties in last 2 years	1.8	2.5	5.0	-0.5	-2.2	-1.9	-1.3	-2.1	-1.0	-1.6	-1.4	1.9	-1.8	-1.5	0.3
Standing height	1.8	18.1	59.9	-6.2	-2.7	-4.8	-3.1	-2.7	-2.8	-7.7	-3.8	3.6	-2.8	-4.7	2.7
Exposure to tobacco smoke outside home	1.8	2.4	4.9	-1.2	-1.7	-1.8	-1.6	-1.9	-1.4	-0.6	-2.2	1.4	-2.0	-1.4	-0.3
Mood swings	1.8	3.3	5.9	2.3	2.3	2.4	1.6	1.9	1.7	0.4	1.1	-2.0	1.7	2.2	-0.5
Diastolic blood pressure, automated reading	1.8	5.6	9.4	3.1	2.2	3.0	2.6	2.5	1.8	1.5	2.7	-2.3	2.4	2.8	-0.1
Qualifications: A levels/AS levels or equivalent	1.7	3.8	7.0	-1.4	-1.9	-2.6	-2.4	-2.4	-1.6	-1.4	-1.6	2.0	-2.1	-2.2	-0.2
Prospective memory result	1.7	2.1	4.2	1.1	1.6	2.1	1.2	1.6	0.3	1.5	1.8	-1.2	1.7	1.5	-0.6
Mouth/teeth dental problems: Mouth ulcers	1.7	2.8	5.1	-1.3	-1.6	-2.0	-2.0	-1.7	-1.1	-1.5	-2.3	1.9	-1.5	-1.9	-0.5
Ever depressed for a whole week	1.7	2.1	4.6	1.5	1.2	1.2	1.5	1.8	1.0	-0.5	1.6	-1.3	1.3	1.6	2.1
Cholesterol lowering medication	1.7	2.6	6.2	2.5	2.1	2.1	1.1	1.9	1.3	1.0	1.4	-1.2	1.6	1.3	0.6
Ever unenthusiastic/disinterested for a whole week	1.6	2.0	8.6	1.6	1.6	1.7	1.0	1.7	0.4	0.9	0.8	-0.7	0.4	1.1	2.9
Mouth/teeth dental problems	1.6	2.5	7.5	2.7	0.5	1.5	1.3	0.9	0.2	2.2	2.3	-1.4	1.2	1.7	-0.9
Frequency of tiredness / lethargy in last 2 weeks	1.6	2.6	4.7	0.3	-1.5	-1.5	-1.9	-1.7	-1.1	-1.9	-2.0	1.5	-2.2	-1.6	1.3
Loud music exposure frequency	1.6	1.8	6.5	-2.5	-1.3	-0.9	-1.2	-1.1	-0.9	0.2	-1.5	1.4	-1.6	-1.5	0.1
Health satisfaction	1.6	2.1	4.8	1.8	1.4	1.3	1.3	1.4	2.2	-2.0	1.0	-1.3	1.2	1.2	0.8
Medication: Ibuprofen	1.6	1.9	5.4	2.3	1.1	2.1	1.2	1.4	-0.0	0.8	1.6	-1.0	1.5	1.4	-0.3
Average weekly spirits intake	1.5	1.8	4.6	-1.4	-1.4	-1.4	-1.2	-1.2	-1.6	-2.1	-1.2	1.1	-1.1	-1.4	0.5
Severe depression (siblings)	1.5	1.7	7.7	-1.3	-1.4	-1.5	-1.1	-1.4	0.2	-2.8	-0.7	0.9	-0.7	-1.0	-0.8
Gout (self-reported)	1.5	2.1	5.1	0.5	2.3	2.0	1.5	1.9	0.6	-0.5	1.0	-1.5	1.8	1.5	0.3
Guilty feelings	1.5	2.3	4.1	2.0	1.5	1.3	1.2	1.4	1.3	-1.4	1.6	-1.6	2.0	1.8	0.2
Medication: Blood pressure	1.5	2.8	7.4	2.2	2.2	2.7	1.4	1.8	1.6	0.8	1.2	-1.2	1.2	1.4	1.4
Medication: Lisinopril	1.5	1.9	4.6	1.7	1.7	2.1	1.3	1.6	1.7	-0.1	1.1	-1.0	1.0	1.1	1.1
Heart disease (siblings)	1.5	1.8	4.7	1.7	1.8	2.2	1.3	1.7	0.4	-0.9	0.7	-0.9	1.2	1.2	1.1
Average weekly fortified wine intake	1.4	1.7	4.5	-0.2	1.8	1.1	0.7	1.8	1.6	0.8	1.6	-0.9	0.8	0.6	2.1
Leg fat percentage (right)	1.4	5.2	9.6	3.1	2.8	3.1	2.0	2.5	1.9	0.1	1.8	-2.4	1.9	2.5	1.7
Medication: Allopurinol	1.4	1.8	3.4	1.1	1.6	1.8	1.5	1.6	0.8	-0.1	1.1	-1.3	1.9	1.6	-0.0
Alcohol intake frequency.	1.4	3.3	14.5	3.8	1.4	1.9	1.6	1.1	1.5	-0.5	2.1	-1.5	1.6	1.8	-0.2
Family relationship satisfaction	1.4	1.8	3.6	1.8	0.7	1.3	1.8	0.9	0.8	-0.6	1.9	-1.4	1.5	1.6	-0.1
Height	1.3	25.4	112.4	-7.7	-2.4	-5.2	-2.8	-2.0	-3.0	-10.6	-3.0	3.2	-2.5	-5.1	5.2
Father’s age at death	1.3	1.8	3.7	1.3	1.0	0.6	1.1	0.7	0.5	1.3	1.7	-1.6	1.9	1.5	-1.9
Medication: Seretide 50 evohaler	1.3	1.5	2.8	1.1	1.0	0.7	1.2	0.8	1.7	0.2	1.0	-1.6	1.6	1.5	-1.2
Supplements: Vitamin C	1.3	1.5	3.4	0.9	1.0	1.3	1.7	1.2	0.0	0.6	1.2	-1.2	1.9	1.4	-1.1
Wears glasses or contact lenses	1.3	1.5	2.9	0.5	0.9	1.3	1.7	1.3	0.3	0.8	1.5	-1.5	1.3	1.5	1.1
Medication: Atenolol	1.2	1.4	2.7	1.2	1.4	1.6	1.3	1.6	1.4	-0.6	0.9	-0.9	1.1	1.0	1.0
Hearing difficulty/problems with background noise	1.2	1.9	4.4	1.1	0.8	1.3	1.4	1.1	1.4	-0.3	2.1	-1.6	1.5	1.9	-0.8
Medication: Cholesterol lowering	1.2	1.8	2.9	-0.5	-1.5	-1.6	-1.4	-1.7	-0.5	-1.1	-1.4	1.7	-1.6	-1.6	-0.5
Lung cancer (father)	1.2	1.4	3.7	-1.0	-0.6	-0.6	-1.4	-0.8	-0.1	1.2	-1.9	1.6	-1.4	-1.5	0.5
Birth weight of first child	1.2	2.2	5.2	-1.9	-1.4	-1.7	-1.2	-1.3	-1.9	0.5	-2.3	1.1	-1.3	-1.6	-0.0
Number of full sisters	1.2	1.5	4.9	-0.6	-1.2	-1.2	-1.0	-1.2	-1.3	0.1	-0.6	1.2	-2.2	-1.1	1.5
Ever had bowel cancer screening	1.2	1.4	2.6	-1.2	-1.6	-1.4	-1.2	-1.6	-1.0	-0.8	-0.3	1.4	-1.0	-1.2	-0.7
Average weekly champagne plus white wine intake	1.2	1.7	4.5	-2.0	-1.3	-1.1	-0.9	-1.1	-1.8	0.2	-0.8	1.3	-0.3	-1.3	-2.1
Supplements: Calcium	1.2	1.4	4.7	-2.2	-0.6	-1.0	-1.3	-0.5	0.1	0.5	-1.4	1.0	-1.5	-1.6	0.8
Basal cell carcinoma (self-reported)	1.2	1.4	3.4	-0.8	-1.8	-1.4	-1.1	-1.8	-0.7	0.2	-0.7	1.2	-1.3	-1.1	-1.0
Neuroticism	1.1	2.6	4.7	1.6	2.0	2.2	1.6	1.8	1.3	1.4	1.3	-1.7	1.7	1.9	-0.1
Angina	1.1	1.4	2.8	0.4	-0.1	-0.1	-1.3	-0.4	-1.4	1.4	-1.7	1.6	-1.6	-1.3	1.2
Medication for hormone replacement therapy	1.1	1.2	3.2	0.3	1.3	0.8	0.4	0.8	0.1	1.7	1.1	-1.0	1.4	0.9	-1.8
Chest pain or discomfort	1.1	1.6	6.1	2.5	1.5	2.0	0.9	1.4	0.6	1.0	0.8	-0.4	0.6	0.9	0.6
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	2.7	-0.2	1.2	1.4	1.1	1.5	1.2	1.1	0.9	-1.0	1.6	1.0	-0.7
Financial situation satisfaction	1.1	1.3	2.3	0.6	1.5	1.2	1.2	1.5	1.0	-0.5	1.0	-1.2	1.3	1.1	1.2
Leg fat percentage (left)	1.1	4.0	7.8	2.7	2.4	2.8	1.8	2.2	1.6	0.2	1.6	-2.1	1.6	2.2	1.2
Neuroticism (Nagel 2018)	1.0	2.3	3.9	1.3	1.7	1.8	1.6	1.5	1.0	1.4	1.3	-1.7	1.8	2.0	-1.0
BMI	1.0	6.0	14.1	2.8	3.0	3.8	2.2	2.8	2.0	2.1	2.1	-2.1	1.8	2.6	0.9
Trunk fat percentage	1.0	4.2	7.8	1.7	2.5	2.8	2.0	2.4	2.2	0.8	1.8	-2.2	1.7	2.1	1.6
Body fat percentage	1.0	4.1	8.3	2.2	2.4	2.9	1.9	2.3	1.9	1.0	1.7	-2.1	1.5	2.1	1.6
Emphysema/chronic bronchitis	1.0	1.2	2.6	-1.2	-1.1	-1.1	-1.2	-1.2	-0.4	-0.4	-1.6	1.0	-1.4	-1.1	0.2
Angina (self-reported)	1.0	1.4	2.5	0.5	-0.1	-0.0	-1.2	-0.3	-1.5	1.4	-1.5	1.6	-1.5	-1.2	1.3
Arm fat percentage (left)	1.0	3.9	8.7	2.2	2.2	3.0	1.7	2.1	1.6	2.3	1.6	-1.8	1.1	2.0	1.5
Alcohol drinker status: Previous	1.0	1.2	3.2	1.8	0.9	1.7	1.1	0.9	0.4	1.3	1.0	-0.7	0.6	1.1	0.2
Breast Cancer	0.9	2.2	4.5	-0.1	-1.5	-1.7	-1.6	-2.1	-1.2	0.9	-1.6	1.2	-1.6	-1.1	-1.9
Systolic Blood Pressure	0.9	4.7	9.8	3.1	2.1	2.9	2.0	1.7	2.2	2.2	1.8	-1.6	2.3	2.2	-1.1
Ever had hysterectomy (womb removed)	0.9	1.0	3.7	-0.4	-0.6	-0.1	-1.2	-0.6	-1.9	-0.9	-0.2	1.5	-0.6	-1.3	-0.9
Sitting height	0.9	6.5	22.7	-3.6	-1.9	-3.0	-1.6	-1.6	-2.0	-4.8	-2.2	2.3	-1.4	-2.8	1.1
Heart attack	0.9	1.2	3.0	1.3	1.4	1.7	0.4	1.3	-0.8	1.7	0.5	-0.2	0.3	0.4	1.1
Trunk fat-free mass	0.9	5.4	16.5	-1.9	-1.5	-2.3	-1.9	-1.7	-2.8	-4.1	-2.4	2.4	-1.9	-2.7	1.1
Worrier / anxious feelings	0.9	1.6	2.7	0.7	1.1	1.5	1.6	1.3	1.2	0.4	1.4	-1.5	1.6	1.6	-0.8
Number of live births	0.9	1.3	3.1	-0.9	-0.6	-0.6	-1.3	-0.8	-1.8	-0.3	-1.5	1.6	-1.4	-1.3	-0.2
Trunk predicted mass	0.9	5.1	16.4	-1.9	-1.4	-2.2	-1.8	-1.6	-2.7	-4.0	-2.3	2.2	-1.8	-2.6	1.2
Medication for pain relief, constipation, heartburn	0.9	1.6	9.9	-3.1	-1.0	-1.7	-0.7	-1.1	0.6	-0.3	-0.9	0.5	-0.6	-0.9	-0.9
Pulse rate, automated reading	0.9	3.0	5.3	-1.0	-2.3	-1.8	-1.5	-1.5	-2.0	-2.1	-1.1	1.6	-2.1	-1.4	2.0
Had major operations	0.9	1.1	2.3	-1.5	-0.9	-1.0	-0.7	-0.6	-1.3	0.1	-0.8	0.9	-1.2	-1.2	1.4
Number of operations (self-reported)	0.9	1.3	3.3	-0.8	-0.7	-0.5	-1.2	-0.6	-1.8	-0.4	-1.2	1.5	-1.6	-1.3	1.3
Age started oral contraceptive pill	0.9	1.2	1.9	1.2	0.9	0.9	1.3	1.2	0.9	-0.6	1.4	-1.2	1.1	1.2	0.9
Crohns Disease (2017)	0.8	1.8	5.1	1.2	0.7	1.3	1.7	0.9	2.3	0.6	1.5	-1.1	1.7	1.2	-1.2
Crohns Disease (2012)	0.8	1.3	2.8	1.0	1.0	1.6	1.2	1.0	0.0	0.3	1.7	-0.8	1.4	1.1	-1.4
Smoking Status	0.8	1.8	11.6	-0.6	-1.2	-0.4	-0.6	-0.9	-0.2	3.4	-0.4	0.9	-0.4	-0.7	-2.4
Sensitivity / hurt feelings	0.8	1.4	2.6	1.6	1.5	1.2	0.7	1.4	1.3	1.3	0.6	-1.3	0.8	1.3	0.8
Medication: Metformin	0.8	1.2	6.5	2.6	-0.1	0.2	0.5	-0.5	0.9	-1.1	0.9	-0.8	0.4	0.9	-1.7
Diabetes (father)	0.8	1.0	5.2	1.4	0.8	0.9	0.6	0.8	0.9	2.3	0.7	-0.7	0.6	0.7	-0.1
Age when periods started (menarche)	0.8	2.0	7.8	-2.8	-1.5	-2.0	-0.9	-1.1	-1.1	0.3	-1.7	0.8	-1.1	-1.2	-0.0
Serious illness, injury or assault to yourself	0.8	0.9	2.4	-0.3	-1.6	-1.2	-0.4	-1.4	-0.6	-1.1	-0.5	0.6	-0.7	-0.8	-1.2
Arm fat percentage (right)	0.8	3.2	7.3	1.9	2.0	2.7	1.5	1.9	1.5	2.3	1.3	-1.7	0.9	1.8	1.5
Illnesses of mother	0.8	1.0	2.7	-0.9	-1.6	-1.4	-0.3	-1.1	-1.5	-0.8	-0.7	0.8	-0.7	-0.7	-0.6
Shortness of breath walking on level ground	0.8	0.9	2.6	0.5	1.1	1.5	1.1	1.0	1.6	1.1	0.5	-0.5	0.5	0.4	0.8
Neck or shoulder pain in last month	0.8	1.1	2.0	1.4	1.4	1.3	0.8	1.4	0.7	0.2	0.8	-0.8	1.0	0.9	1.0
Mean time to correctly identify matches	0.8	1.6	3.1	1.7	1.3	1.1	1.2	1.1	1.8	0.0	1.3	-1.5	1.4	1.5	-0.2
Heart disease (mother)	0.8	1.0	2.6	-0.2	-0.1	0.5	-1.2	-0.4	-1.1	0.4	-0.9	1.6	-1.4	-1.1	1.2
Comparative height size at age 10	0.8	4.3	37.0	-1.9	0.7	-0.7	-0.2	0.3	-0.3	-6.1	-0.6	0.4	-0.1	-1.2	2.7
Knee pain experienced in last month	0.8	1.3	2.9	-0.7	-1.1	-0.7	-1.5	-1.3	-1.2	-0.3	-1.0	1.7	-1.5	-1.4	0.0
Illnesses of father: Heart disease	0.8	1.2	7.5	0.3	1.4	0.8	-0.1	1.1	1.6	-0.2	-0.2	-0.2	-0.3	0.0	2.7
Commuting to job workplace: Public transport	0.8	1.0	7.9	-1.2	0.3	0.4	0.1	0.8	-0.7	0.9	0.4	0.2	-0.7	-0.2	2.8
Alcohol drinker status: Never	0.8	0.9	2.3	1.5	1.2	1.1	0.8	1.1	0.8	-0.3	0.7	-0.9	0.7	0.9	1.0
Unable to work because of sickness or disability	0.8	1.0	3.1	0.8	1.2	1.4	0.5	1.2	0.4	1.3	0.4	-0.7	0.3	0.8	1.7
Ever used hormone-replacement therapy (HRT)	0.7	0.8	2.2	-0.5	1.5	1.4	0.6	1.4	0.2	0.5	0.6	-0.7	1.1	0.6	0.7
Nervous feelings	0.7	1.4	3.2	0.7	1.3	1.8	1.1	1.4	-0.2	1.1	1.6	-1.0	0.8	1.1	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	5.8	-0.7	-0.8	-1.7	-1.3	-0.9	-1.2	-2.4	-1.2	1.1	-0.7	-1.2	0.5
Hip circumference	0.7	2.9	6.7	1.4	2.3	2.2	1.6	2.2	1.4	-0.7	1.0	-1.4	1.1	1.1	2.6
Depression (self-reported)	0.7	0.8	1.9	0.6	1.4	1.4	0.7	1.4	0.1	0.2	0.6	-0.7	0.6	0.6	1.4
Tense / ‘highly strung’	0.7	1.1	3.2	0.4	1.3	1.8	0.9	1.0	0.9	0.9	1.2	-0.8	1.2	1.1	-0.7
Ever highly irritable/argumentative for 2 days	0.7	0.9	1.5	1.1	1.0	1.2	1.1	1.2	0.8	-0.2	0.6	-0.8	0.7	1.1	0.8
Medication: Amlodipine	0.7	0.9	2.3	0.7	0.4	1.2	1.3	0.6	1.5	0.8	1.1	-0.8	1.0	1.0	-0.7
Suffer from ‘nerves’	0.7	1.1	2.4	0.9	0.8	1.4	1.5	1.0	0.8	-0.2	1.5	-1.1	1.0	1.3	0.2
Whole body fat-free mass	0.7	4.0	9.7	-1.5	-1.4	-1.9	-1.6	-1.5	-2.4	-3.1	-2.2	2.2	-1.8	-2.4	1.1
Osteoporosis (self-reported)	0.7	0.9	8.1	0.9	-0.1	-0.2	0.2	-0.2	0.6	0.5	0.2	-0.6	0.7	0.6	-2.9
Osteoarthritis (self-reported)	0.7	0.9	3.5	-1.9	-0.6	-0.8	-0.8	-0.9	-0.2	-0.8	-1.5	0.7	-0.8	-1.0	0.1
Whole body water mass	0.7	3.7	9.8	-1.4	-1.2	-1.8	-1.6	-1.4	-2.3	-3.1	-2.1	2.1	-1.8	-2.3	1.2
Heart attack/myocardial infarction (self-reported)	0.7	0.9	2.3	1.4	1.2	1.5	0.3	1.1	-0.6	1.5	0.4	-0.1	0.1	0.2	1.0
Depressed Affect (Nagel 2018)	0.6	1.3	2.5	1.3	1.2	1.3	1.1	0.8	0.5	1.3	0.8	-1.3	1.0	1.6	-0.7
Bipolar Disorder (2011)	0.6	0.6	3.6	-0.2	-0.9	-0.8	-0.2	-0.6	0.0	-1.9	0.6	-0.2	0.3	-0.1	-1.2
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	2.2	1.4	0.7	0.8	0.3	0.9	-0.6	-0.3	1.0	-0.4	0.2	0.6	1.5
Stomach or abdominal pain in last month	0.6	0.7	3.0	1.6	0.3	0.2	-0.2	0.2	-1.2	-1.7	-0.1	0.1	-0.5	-0.1	1.2
Medication: Simvastatin	0.6	0.9	3.7	1.9	0.4	0.7	0.9	0.4	0.8	-0.2	0.6	-0.6	1.2	1.0	-1.1
Neuroticism score	0.6	1.2	2.3	1.3	1.0	1.5	1.1	1.0	0.8	0.6	1.0	-1.0	1.2	1.4	-0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	4.2	-0.5	0.4	0.7	0.4	0.7	1.2	2.0	0.8	-0.4	1.1	0.7	-1.0
Glaucoma (self-reported)	0.6	0.7	3.9	-0.7	0.8	0.3	-0.2	0.7	-0.4	-1.3	-0.1	0.6	-0.4	-0.7	2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	2.0	-0.2	0.7	1.1	0.8	0.9	1.4	1.3	0.5	-0.7	0.9	1.0	-0.6
Migraine (self-reported)	0.6	0.8	1.9	0.7	-1.4	-1.1	-0.7	-1.3	-1.1	0.4	-0.7	0.5	-1.0	-0.5	-0.7
Arm predicted mass (right)	0.6	3.0	14.1	-0.9	-0.6	-1.3	-1.2	-0.9	-2.1	-3.8	-1.8	1.6	-1.2	-1.8	1.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	3.2	-1.0	-0.9	-0.7	-1.5	-0.9	-0.7	0.8	-1.8	1.2	-1.2	-0.9	-0.7
Number of self-reported non-cancer illnesses	0.6	1.0	2.4	-0.2	-0.5	-0.5	-1.1	-0.5	-0.9	-0.9	-1.1	1.2	-1.5	-1.2	1.2
Ever taken oral contraceptive pill	0.6	0.7	1.4	0.6	-1.1	-1.2	-0.9	-1.0	-0.8	-0.8	-0.7	0.6	-1.0	-0.6	0.5
Basal metabolic rate	0.6	3.2	8.5	-1.1	-1.0	-1.5	-1.5	-1.2	-2.0	-2.9	-2.0	1.9	-1.7	-2.1	1.4
Ovarian Cancer	0.5	0.6	4.1	-0.5	-0.3	-0.6	0.2	-0.5	0.2	0.1	0.9	-0.7	1.0	0.5	-2.0
Coronary Artery Disease (CAD)	0.5	0.6	1.2	-0.2	-0.9	-0.6	-1.0	-1.1	0.0	-0.8	-0.7	0.9	-0.8	-0.8	-0.6
Fasting Glucose	0.5	0.6	2.3	-0.6	-0.6	-0.8	-0.4	-0.9	-1.5	-0.8	-0.9	0.3	-0.6	-0.8	0.0
Lung FEV1/FVC ratio	0.5	2.4	4.7	1.8	1.8	2.1	1.1	1.7	0.3	2.2	1.4	-1.3	1.6	1.6	-0.9
Leg fat-free mass (left)	0.5	2.4	4.3	-1.1	-1.1	-1.3	-1.5	-1.2	-1.6	-1.5	-1.9	1.9	-1.8	-2.1	1.2
Qualifications: CSEs or equivalent	0.5	0.7	3.4	1.9	-0.1	0.4	0.2	0.1	0.9	1.6	0.6	-0.1	-0.4	0.4	0.3
Body mass index (BMI)	0.5	2.3	8.2	2.9	1.6	2.3	1.0	1.3	0.5	1.9	0.9	-1.0	0.6	1.4	0.6
Hair/balding pattern: Pattern 2	0.5	0.6	2.0	1.4	0.7	0.7	0.6	0.4	1.0	-0.4	0.5	-0.9	0.7	0.7	-1.0
Hayfever/allergic rhinitis (self-reported)	0.5	0.7	2.0	0.3	0.8	0.3	1.0	1.0	0.7	0.8	-0.1	-1.4	0.4	1.1	0.8
Time employed in main current job	0.5	0.6	4.9	0.7	-0.2	-0.2	0.3	-0.2	-0.6	-2.2	0.0	-0.6	-0.3	0.6	0.2
Pulse rate	0.5	0.9	3.7	-1.1	-0.9	-1.0	-0.4	-0.6	-0.8	-1.9	0.0	0.2	-1.0	-0.2	1.3
Happiness	0.5	0.6	1.6	1.1	0.4	0.4	0.8	0.5	1.3	-0.9	0.6	-0.8	0.5	0.7	0.2
Hair/balding pattern: Pattern 4	0.5	1.2	4.9	0.1	1.0	1.1	0.8	1.5	0.4	2.2	0.7	-0.8	0.9	1.0	1.1
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	2.8	-1.5	0.2	-0.2	-0.4	-0.4	0.4	-1.7	-1.2	0.2	-0.5	-0.6	0.1
Blood clot in the leg (DVT)	0.5	0.7	1.8	-0.4	-1.1	-0.6	-0.8	-0.7	0.0	0.0	-0.9	1.3	-1.0	-1.1	0.5
Medication: Paracetamol	0.5	0.8	6.8	2.6	-0.3	0.4	-0.5	-0.2	-0.9	0.8	-0.4	0.5	-0.4	-0.2	-0.0
Comparative body size at age 10	0.5	1.5	9.2	1.9	0.1	0.8	0.1	-0.1	0.6	3.0	0.6	-0.1	-0.1	0.7	-1.8
Number of children fathered	0.5	0.5	1.8	0.7	1.1	0.6	0.2	0.8	0.6	1.4	-0.7	-0.5	0.5	0.6	0.2
Overall health rating	0.5	1.1	3.6	1.9	1.4	1.6	0.4	1.1	0.8	0.5	0.4	-0.5	0.2	0.6	1.2
Leg fat-free mass (right)	0.5	2.7	4.7	-1.3	-1.3	-1.5	-1.6	-1.4	-1.9	-1.4	-2.0	2.1	-1.9	-2.2	0.9
Long-standing illness, disability or infirmity	0.5	0.7	2.0	1.4	0.9	1.3	0.8	0.9	0.7	-0.3	0.7	-0.7	0.5	0.7	0.7
Smoking status: Current	0.5	0.9	2.9	0.8	0.8	1.0	0.6	0.8	1.0	1.7	0.5	-0.5	1.0	0.8	-1.1
Leg predicted mass (right)	0.5	2.7	4.7	-1.2	-1.3	-1.5	-1.6	-1.4	-1.8	-1.4	-2.0	2.1	-1.9	-2.2	0.8
Mother’s age at death	0.5	0.6	2.0	0.4	0.9	0.1	0.4	0.7	1.3	1.4	0.2	-0.9	0.7	0.7	0.7
Medication: Bendroflumethiazide	0.5	0.8	2.5	1.5	0.8	0.9	0.7	0.9	0.5	-0.2	1.0	-0.7	0.5	0.8	1.6
Medication: Paracetamol	0.5	0.7	5.7	2.4	-0.2	0.7	-0.3	0.1	-0.5	1.4	-0.3	0.5	-0.2	-0.1	0.3
Medication: Atorvastatin	0.5	0.6	2.5	0.7	0.2	0.6	-0.3	0.2	0.1	1.6	-0.4	0.6	-1.0	-0.4	1.3
Arm fat-free mass (left)	0.5	2.4	11.9	-0.6	-0.5	-1.1	-0.9	-0.7	-2.0	-3.5	-1.7	1.3	-1.0	-1.5	1.6
Risk taking	0.5	0.8	4.5	-2.1	-1.0	-1.2	-0.2	-0.6	-0.8	-0.1	-0.2	0.6	-0.4	-0.8	-0.4
Arm predicted mass (left)	0.5	2.4	11.1	-0.7	-0.4	-1.0	-0.9	-0.6	-2.1	-3.3	-1.8	1.3	-0.9	-1.5	1.6
Depression (Nagel 2018)	0.4	0.6	3.9	0.2	-0.6	-0.7	-0.6	-1.1	-0.4	-0.0	-0.3	0.3	0.0	-0.1	-2.0
Schizophrenia (2018)	0.4	0.8	3.5	0.7	0.4	0.8	1.0	0.6	0.0	-0.1	1.9	-1.0	0.9	1.1	-0.3
Irritable Bowel Disease (IBD)	0.4	0.9	2.4	-0.7	-1.6	-1.2	-0.7	-1.2	-0.5	-0.5	-0.6	1.2	-0.7	-1.1	-0.9
Reaction Time	0.4	0.7	2.9	1.4	-0.0	0.2	0.7	-0.0	1.7	-0.4	0.4	-0.6	0.9	0.7	-1.1
Body Mass Index (BMI) (2010)	0.4	0.5	4.6	0.6	0.1	0.1	-0.5	-0.1	0.0	2.1	-0.5	0.1	-0.3	-0.1	-0.9
Triglycerides	0.4	0.7	4.7	0.0	-1.0	-0.9	-0.6	-0.8	0.0	-2.2	-0.4	0.5	-0.6	-0.6	-0.4
Waist Hip Ratio (WHR)	0.4	1.8	4.0	0.5	-1.9	-1.3	-1.2	-2.0	-1.0	-1.2	-0.9	1.2	-1.0	-1.0	-1.8
Frequency of depressed mood in last 2 weeks	0.4	0.6	1.4	0.3	-0.9	-0.8	-0.8	-1.2	-0.6	-1.0	-0.8	0.3	-0.5	-0.3	-1.1
Eye problems/disorders: Diabetes related eye disease	0.4	0.4	1.0	-1.0	-0.6	-0.9	-0.6	-0.8	-0.2	-0.0	-0.1	0.3	-0.3	-0.5	-1.0
Supplements: Zinc	0.4	0.4	1.7	-0.7	0.4	-0.1	-0.5	-0.2	-1.3	-0.4	-1.1	0.5	-0.5	-0.7	0.1
Impedance of leg (right)	0.4	2.1	15.2	-0.5	0.6	0.1	1.0	0.7	1.5	-3.9	0.8	-1.3	1.6	0.8	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	2.0	-0.8	-1.0	-1.4	-1.1	-1.0	-0.8	-1.2	-0.8	1.0	-0.4	-1.0	-0.4
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.3	0.8	-0.8	-0.2	0.8	-0.5	0.6	0.5	0.1	-0.6	0.4	0.6	-1.2
Impedance of leg (left)	0.4	1.8	14.1	-0.8	0.4	-0.1	0.9	0.5	1.2	-3.8	0.5	-1.0	1.5	0.6	0.0
Leg predicted mass (left)	0.4	2.3	4.0	-1.0	-1.1	-1.3	-1.4	-1.2	-1.6	-1.4	-1.8	1.9	-1.8	-2.0	1.1
Trunk fat mass	0.4	1.6	3.4	1.0	1.7	1.8	1.3	1.6	1.2	-0.2	1.0	-1.3	1.0	1.1	1.5
Alcohol usually taken with meals	0.4	0.7	2.4	-0.2	0.7	0.5	1.0	0.9	0.5	0.7	1.5	-0.6	1.0	0.6	-0.7
Illnesses of siblings	0.4	0.5	1.4	-0.4	-0.9	-0.4	0.8	-0.3	-0.0	1.0	0.5	-0.5	0.7	0.7	-1.2
Hair/balding pattern: Pattern 3	0.4	0.5	2.0	0.4	0.2	0.3	0.9	0.4	-0.3	0.6	1.4	-0.9	0.2	1.0	1.1
Pulse wave Arterial Stiffness index	0.4	0.5	0.9	0.1	0.7	0.9	0.5	0.9	0.7	-0.9	0.8	-0.4	0.8	0.3	0.5
Arm fat mass (right)	0.4	1.4	3.5	1.6	1.5	1.9	0.9	1.3	0.6	0.9	0.6	-1.0	0.4	1.1	1.7
Breastfed as a baby	0.4	0.4	1.2	-0.2	0.4	1.0	1.1	0.7	-0.3	0.2	0.5	-0.5	0.9	0.7	-0.8
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.4	-0.5	-1.0	-0.7	-0.3	-0.9	-0.5	-1.2	-0.2	0.6	-0.6	-0.6	-0.4
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.3	-0.3	0.8	0.9	0.6	0.6	0.9	1.1	0.1	-0.5	0.8	0.5	-0.8
Arm fat-free mass (right)	0.4	2.3	10.5	-0.6	-0.4	-1.0	-0.9	-0.6	-2.1	-3.2	-1.6	1.4	-0.9	-1.5	1.4
Pulse wave peak to peak time	0.4	0.5	1.3	-0.5	-0.8	-1.1	-0.5	-1.0	-0.8	0.3	-0.9	0.4	-0.8	-0.5	-0.3
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.5	0.0	1.2	0.7	0.3	0.8	0.3	-0.3	0.6	-0.6	0.2	0.4	1.2
Medication: Omeprazole	0.4	0.5	2.5	0.2	-0.5	-0.5	-0.6	-0.6	1.3	-0.3	-0.0	0.2	0.2	-0.3	-1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.2	0.7	0.2	1.1	0.8	0.5	1.1	0.0	1.1	-0.3	0.5	0.6	0.1
Whole body fat mass	0.4	1.8	4.2	1.5	1.7	2.0	1.2	1.6	0.9	0.1	0.9	-1.2	0.9	1.2	1.7
Leg fat mass (right)	0.4	1.7	3.8	1.9	1.7	1.9	1.0	1.5	0.5	-0.3	0.5	-1.0	0.6	1.1	1.9
Medication: Aspirin	0.4	0.5	2.8	1.7	1.0	1.1	0.2	0.7	-0.5	-0.2	-0.1	0.3	0.3	0.0	0.6
Medication: Aspirin	0.4	0.5	1.5	1.2	0.8	0.7	-0.2	0.5	-0.8	0.2	-0.6	0.8	-0.2	-0.4	1.0
Medication: Gliclazide	0.4	0.5	1.6	1.3	0.2	0.3	0.9	0.3	0.5	0.2	0.9	-0.9	0.7	1.0	-0.5
Illnesses of father: None of the above (group 1)	0.4	0.5	1.4	-1.2	-0.7	-0.4	-0.2	-0.5	-0.9	-0.1	-0.9	0.6	-0.2	-0.5	-1.1
Arm fat mass (left)	0.4	1.6	4.1	1.6	1.7	2.0	1.0	1.5	0.6	0.7	0.6	-1.0	0.5	1.1	1.8
Tinnitus: Yes, now most or all of the time	0.4	0.5	0.9	-0.6	-0.7	-0.9	-0.8	-0.9	-0.5	-0.7	-0.3	0.4	-0.9	-0.7	-0.2
Average weekly beer plus cider intake	0.4	0.6	2.5	0.7	-0.4	-0.5	-0.9	-0.8	-0.2	-1.6	-1.0	0.7	-0.4	-0.6	-0.7
Myopia	0.4	0.5	1.1	0.3	-0.8	-0.7	-1.0	-0.6	-0.6	-0.5	0.1	1.1	-1.0	-0.9	0.4
Vascular/heart problems diagnosed by doctor	0.4	1.1	3.4	-0.7	-1.8	-1.8	-0.4	-1.3	-0.8	-0.6	0.0	0.5	-0.2	-0.4	-1.8
Alzheimer’s Disease (in father)	0.3	0.3	1.3	-0.3	-0.0	0.2	0.3	-0.0	-0.6	1.1	0.2	-0.1	0.3	0.0	-1.1
Lupus	0.3	0.5	3.0	-0.2	0.4	0.3	0.1	0.8	1.3	0.0	0.3	0.0	-0.3	-0.0	1.7
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	1.4	1.0	-0.4	-0.3	0.6	-0.1	-0.4	-1.2	0.6	-0.6	0.2	0.4	0.1
Maternal smoking around birth	0.3	0.4	2.3	-0.4	0.7	0.6	-0.3	0.2	0.1	1.5	-1.0	-0.2	0.1	0.1	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.0	0.7	1.0	1.0	0.6	0.7	0.1	-0.1	0.4	-0.6	0.8	0.7	-0.7
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.4	-0.1	1.2	1.0	0.9	0.9	0.2	0.6	0.5	-0.9	0.5	1.0	0.4
Medication: Levothyroxine sodium	0.3	0.6	1.3	-0.6	-0.2	-0.5	-0.9	-0.3	0.1	-0.7	-0.3	0.9	-1.1	-1.0	1.1
Waist circumference	0.3	1.0	3.2	1.8	1.3	1.5	0.7	1.1	0.8	-0.2	0.5	-0.7	0.4	0.6	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	1.1	-0.7	-0.6	-0.6	-0.4	-0.7	-0.7	-0.7	-1.1	0.5	-0.3	-0.4	-1.0
Diabetes (self-reported)	0.3	0.4	1.2	1.1	-0.7	-0.3	-0.6	-1.0	0.2	-0.3	-0.5	0.6	-0.8	-0.5	-0.7
Medication: Lansoprazole	0.3	0.4	1.9	1.4	0.5	0.2	-0.1	0.3	-0.8	-0.7	0.0	-0.3	0.1	0.2	1.0
Exposure to tobacco smoke at home	0.3	0.4	1.1	0.3	-0.5	-0.2	-0.8	-0.8	-0.4	0.3	-0.4	1.0	-0.6	-0.7	-0.6
Commuting to job workplace: Car/motor vehicle	0.3	0.4	2.1	0.1	-0.1	-0.2	-0.7	-0.7	0.7	0.2	-0.5	0.4	-0.2	-0.4	-1.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.1	-0.3	-0.3	-0.3	-0.4	-0.3	0.3	-0.4	-0.2	0.6	-0.9	-0.8	1.1
Asthma (self-reported)	0.3	0.5	1.4	1.2	0.9	1.0	0.8	0.7	0.2	0.7	0.4	-0.7	0.0	0.7	0.3
Miserableness	0.3	0.6	2.0	1.4	0.0	0.4	0.7	0.2	-0.4	-1.3	0.7	-0.7	0.6	1.0	-0.4
Irritability	0.3	0.5	1.8	0.6	0.5	1.3	0.7	0.9	-0.7	0.7	0.2	-0.3	0.6	0.8	-0.4
Impedance of whole body	0.3	1.4	3.8	-1.6	0.6	0.2	1.0	0.9	1.9	-1.8	0.9	-1.2	1.3	0.8	0.6
Leg fat mass (left)	0.3	1.2	2.9	1.6	1.5	1.7	0.8	1.2	0.3	-0.1	0.3	-0.8	0.5	0.9	1.6
Bipolar Disorder (2018)	0.2	0.3	1.8	-1.1	-0.4	-0.4	0.0	-0.2	0.0	-0.4	-0.3	-0.1	0.3	-0.2	-1.3
Bipolar Disorder or Schizophrenia	0.2	0.5	1.5	-0.1	0.1	0.3	0.8	0.3	0.0	-0.3	1.2	-0.8	0.9	0.7	-1.0
Schizophrenia vs Biploar Disorder	0.2	0.2	0.8	0.3	-0.7	-0.5	-0.3	-0.5	0.0	-0.9	0.1	0.6	-0.4	-0.2	-0.1
Major Depression (MDD)	0.2	0.3	1.1	0.1	0.4	0.4	0.3	0.8	0.0	1.1	0.7	-0.2	0.5	0.5	0.6
Age at First Birth	0.2	0.3	1.0	0.4	0.5	0.3	0.2	0.1	0.2	0.5	0.4	-0.3	1.0	0.2	-1.0
HDL Cholesterol	0.2	0.4	1.6	1.3	0.8	0.2	-0.5	0.1	0.0	1.0	-0.4	-0.1	-0.2	0.1	1.1
Schizophrenia (2014)	0.2	0.4	1.3	0.7	0.5	0.6	0.7	0.4	0.0	0.4	1.1	-0.7	0.6	0.8	-0.5
Type 2 Diabetes (T2D) (2012)	0.2	0.2	1.6	0.5	-0.1	-0.1	0.1	0.0	0.0	-1.3	0.2	-0.1	-0.2	-0.1	0.5
Blood Platelet Count	0.2	2.9	5.0	-1.2	-2.2	-2.1	-2.2	-1.9	-1.8	0.1	-1.5	1.8	-2.0	-1.6	0.7
Blood Red Count	0.2	2.0	6.6	0.8	1.5	1.1	1.1	1.6	0.8	-1.9	1.1	-1.2	0.9	1.2	2.6
Heel T-Score	0.2	2.0	10.1	-0.1	-1.0	-1.3	-0.6	-1.2	-1.2	-3.2	0.2	0.3	0.6	-0.3	-2.6
Cardiovascular Disease	0.2	0.6	1.5	-0.6	0.2	0.5	-0.9	-0.3	1.0	-0.3	-1.2	0.9	-1.0	-0.9	0.6
Type 2 Diabetes (T2D) (2018)	0.2	0.4	3.1	1.8	-0.2	-0.2	-0.3	-0.6	0.6	-0.9	-0.3	0.1	-0.4	-0.0	0.0
Chronotype (morning person)	0.2	0.6	1.2	0.4	0.8	0.9	1.0	0.6	-0.2	-0.1	0.9	-1.1	0.7	1.1	-0.0
Number of treatments/medications taken	0.2	0.3	0.6	0.7	0.4	0.7	-0.5	0.2	-0.8	-0.4	-0.2	0.7	-0.4	-0.5	0.7
Diabetes (mother)	0.2	0.3	1.0	0.2	0.2	-0.6	-0.2	-0.1	0.9	-0.5	-0.2	-0.5	-0.5	0.3	1.0
Townsend deprivation index at recruitment	0.2	0.2	1.2	1.1	0.2	-0.0	-0.2	0.3	0.3	0.9	-0.5	-0.3	0.1	0.3	-0.1
Current tobacco smoking	0.2	0.4	2.5	0.3	0.2	0.5	0.1	0.2	0.5	1.6	-0.1	0.1	0.4	0.2	-1.0
Fed-up feelings	0.2	0.3	1.0	0.8	0.5	0.7	-0.1	0.1	-0.1	1.0	-0.1	-0.4	-0.1	0.4	-0.8
Taking other prescription medications	0.2	0.3	0.7	0.4	0.6	0.8	0.6	0.7	0.3	-0.4	0.6	-0.5	0.6	0.4	0.0
High blood pressure	0.2	0.6	1.8	0.3	1.2	1.3	0.3	0.8	1.0	0.0	-0.1	-0.3	0.1	0.2	1.4
Number of incorrect matches in round	0.2	0.3	1.8	0.5	1.3	0.9	0.1	0.6	-0.2	-0.1	0.6	-0.4	0.1	0.4	0.3
Had menopause	0.2	0.2	1.1	-1.0	0.3	-0.0	0.3	0.3	0.1	-0.4	0.3	-0.5	0.7	0.1	-0.2
Had other major operations	0.2	0.2	0.9	-0.6	0.5	0.5	0.1	0.3	0.6	0.6	0.3	-0.1	-0.4	0.2	0.9
Medication: Ramipril	0.2	0.2	0.7	-0.4	-0.0	-0.1	-0.3	-0.3	-0.2	-0.7	-0.5	0.4	-0.5	-0.5	0.8
Weight	0.2	0.8	3.2	-0.0	0.2	0.0	-0.5	-0.1	-0.8	-1.7	-0.9	0.7	-0.8	-0.8	1.8
Impedance of arm (right)	0.2	0.9	5.9	-2.4	-0.2	-0.4	0.3	0.2	1.9	-0.1	0.3	-0.4	0.2	-0.1	0.6
Mouth/teeth dental problems: Dentures	0.2	0.4	1.7	-1.3	-0.5	-0.7	-0.1	-0.2	-0.1	-1.2	-0.5	0.4	-0.3	-0.5	0.5
Asthma	0.2	0.3	1.3	1.1	0.7	0.8	0.7	0.5	0.2	0.3	0.3	-0.6	-0.1	0.6	0.3
Impedance of arm (left)	0.2	1.0	4.6	-1.9	0.2	0.1	0.7	0.6	2.1	-0.3	0.9	-0.8	0.6	0.4	0.7
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	0.8	0.4	0.2	0.2	0.5	0.3	0.4	0.9	0.7	-0.9	0.9	0.7	-0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.9	-0.9	-0.3	-0.6	-0.8	-0.4	-0.2	0.1	-0.1	0.8	-0.7	-1.0	0.3
High blood pressure (siblings)	0.2	0.3	1.4	0.3	0.8	0.1	-0.6	0.2	0.7	-1.2	-0.1	0.4	-0.4	-0.5	0.7
Number of full brothers	0.2	0.2	0.9	1.0	-0.3	0.0	-0.3	-0.3	0.5	-0.2	-0.2	0.6	-0.7	-0.1	0.8
Worry too long after embarrassment	0.2	0.4	1.1	1.0	0.3	0.1	0.4	0.2	0.2	0.1	0.4	-0.7	0.9	0.7	-1.0
Eye problems/disorders: None of the above	0.2	0.2	0.8	0.4	-0.1	-0.6	-0.9	-0.4	-0.5	-0.6	-0.2	0.3	-0.3	-0.3	0.4
Hypertension (Self-reported)	0.2	0.6	2.9	-0.0	1.0	1.0	-0.1	0.6	1.0	-0.1	-0.6	0.1	-0.3	-0.3	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	0.7	0.3	0.3	-0.5	-0.6	-0.2	0.8	-0.3	-0.4	-0.2	-0.4	-0.1	0.6
Handedness (chirality/laterality): Left-handed	0.2	0.3	1.2	-1.1	-0.8	-1.0	-0.2	-0.4	0.2	-0.4	-0.2	-0.1	0.1	-0.1	-0.2
Loneliness, isolation	0.2	0.2	1.1	1.0	0.1	0.1	-0.1	0.0	-1.0	-0.5	-0.4	-0.1	0.1	0.3	0.4
Diabetes diagnosed by doctor	0.2	0.4	1.5	1.2	-0.4	-0.3	-0.6	-0.9	-0.2	-0.4	-0.3	0.4	-0.9	-0.4	-0.0
Friendships satisfaction	0.2	0.2	0.7	0.2	-0.6	-0.6	0.4	-0.3	-0.5	-0.8	0.3	-0.3	0.3	0.2	-0.6
Commuting to job workplace: Walk	0.2	0.3	0.9	0.1	-0.2	0.0	0.7	0.5	-0.4	-0.8	1.0	-0.4	0.4	0.5	-0.1
Eye problems/disorders: Glaucoma	0.2	0.2	1.1	-0.3	0.2	0.5	-0.2	0.3	-0.4	0.1	0.2	0.6	-0.3	-0.5	1.0
High cholesterol (Self-reported)	0.2	0.4	2.1	-0.1	-0.0	-0.3	-0.7	-0.4	0.8	-1.5	-0.3	0.8	-0.6	-0.6	-0.2
Illnesses of father: High blood pressure	0.2	0.2	1.0	1.0	-0.7	-0.3	0.0	-0.3	0.6	-0.0	0.4	0.4	-0.6	-0.2	0.3
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	2.0	0.4	-0.1	-0.3	-0.5	-0.2	1.4	-0.5	0.3	-0.0	0.3	-0.1	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	0.7	-0.1	-0.3	0.1	-0.1	-0.0	0.7	0.6	-0.4	0.7	-0.4	-0.5	0.8
Mean Putamen Volume	0.1	0.1	0.7	-0.2	-0.4	-0.2	-0.1	-0.3	-0.4	-0.8	-0.3	0.2	-0.2	-0.0	-0.1
LDL Cholesterol	0.1	0.2	0.4	-0.1	0.1	0.3	0.6	0.4	0.0	0.6	0.3	-0.6	0.4	0.7	-0.2
Neuroticism (2016)	0.1	0.1	0.4	0.1	0.4	0.4	-0.0	0.6	-0.6	-0.6	-0.0	0.1	0.4	0.2	-0.0
Primary Biliary Cirrhosis	0.1	0.2	0.8	0.7	-0.2	0.3	0.3	-0.0	0.0	-0.4	0.3	-0.2	0.4	0.5	-0.9
Blood Eosinophil Count	0.1	0.4	2.1	1.4	-0.1	0.4	0.4	-0.0	0.5	1.3	0.7	-0.0	0.1	0.4	-0.2
Allergy or Eczema	0.1	0.3	1.0	-1.0	0.4	0.1	0.0	0.1	-0.8	0.2	-0.3	-0.1	-0.6	0.1	0.9
Hypothyroidism (self reported)	0.1	0.1	0.4	-0.3	-0.1	-0.4	-0.5	-0.3	0.3	0.3	-0.0	0.6	-0.3	-0.5	-0.4
Respiratory disease	0.1	0.3	0.8	0.9	-0.2	0.2	0.7	-0.3	0.2	0.7	0.2	-0.5	-0.0	0.5	-0.9
Tanning	0.1	1.6	3.9	1.1	0.6	0.6	1.2	0.6	0.7	2.0	1.2	-1.1	1.7	1.3	-1.9
Pack years adult smoking proportion	0.1	0.1	0.4	0.6	-0.3	-0.0	0.1	-0.3	-0.5	0.5	-0.2	-0.1	0.0	0.2	0.1
High blood pressure (mother)	0.1	0.2	0.7	0.6	0.4	0.3	-0.2	0.1	0.6	0.8	0.0	0.1	-0.0	-0.1	-0.5
Allergy	0.1	0.2	0.9	0.1	0.1	-0.2	0.1	0.4	0.9	-0.1	0.4	-0.4	1.0	0.2	-0.4
Alcohol intake versus 10 years previously	0.1	0.1	0.5	0.7	0.2	0.0	-0.1	-0.0	0.5	-0.4	-0.0	-0.4	-0.2	0.0	0.7
Pulse wave reflection index	0.1	0.2	0.8	0.1	0.5	0.5	-0.2	0.4	0.9	0.4	0.4	0.1	0.4	0.0	-0.3
Birth weight	0.1	0.3	0.7	-0.9	-0.3	-0.4	-0.5	-0.3	-0.8	-0.7	-0.6	0.5	-0.1	-0.6	-0.4
Medication: Blood pressure	0.1	0.2	1.0	0.2	0.2	0.6	0.1	0.2	0.4	-0.5	0.2	0.3	-0.2	-0.1	1.0
Age at last live birth	0.1	0.2	0.7	0.2	-0.0	-0.8	-0.3	-0.4	0.1	0.6	-0.6	0.1	0.1	-0.3	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.4	0.7	-0.6	-0.2	-0.2	-0.3	0.0	0.2	0.1	0.2	-0.6	-0.0	0.5
Eye problems/disorders: Cataract	0.1	0.2	0.5	0.1	-0.7	-0.4	0.6	-0.2	-0.1	-0.3	0.2	-0.3	0.1	0.1	-0.7
Pain type(s) experienced in last month: Hip pain	0.1	0.2	0.6	-0.5	-0.1	-0.3	-0.6	-0.1	0.1	-0.0	-0.5	0.5	-0.4	-0.8	0.4
Fractured/broken bones in last 5 years	0.1	0.1	0.4	0.6	0.4	0.1	0.1	0.2	0.1	-0.7	0.2	-0.6	0.4	0.4	0.0
Pack years of smoking	0.1	0.2	0.9	1.0	0.3	0.3	0.5	0.2	-0.3	0.4	0.2	-0.5	0.4	0.5	0.3
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood White Count	0.0	0.3	1.6	1.2	-0.5	0.4	-0.1	0.1	0.7	-0.5	0.9	0.6	0.2	0.1	0.5
Hair Pigment	0.0	1.3	2.9	-0.4	-0.1	-0.3	-1.6	-0.6	-1.0	-1.7	-1.5	1.4	-1.4	-1.4	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.2	-0.4	-0.1	-0.2	0.0	-0.1	-0.1	-0.1	0.2	-0.3	-0.3	0.2	-0.0
Age at first live birth	0.0	0.1	0.4	0.4	0.2	-0.6	-0.4	-0.1	0.1	0.2	-0.3	-0.0	0.3	-0.2	-0.2

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