TWAS hub - DNAJC9-AS1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Visceral Omentum	0.1660	0.0850	3.5e-03	-0.002	NA	0.024	NA	0.011	4.6e-01	NA	1.9e-02	NA	7.9e-02
2	GTEx	Cells Transformed fibroblasts	0.1160	0.0500	5.6e-04	0.004	NA	0.053	NA	0.051	1.4e-01	NA	7.5e-05	NA	1.1e-04
3	GTEx	Nerve Tibial	0.0993	0.0494	3.9e-03	0.072	NA	0.049	NA	0.056	8.1e-06	NA	2.1e-04	NA	8.4e-05
4	GTEx	Pituitary	0.3240	0.1370	1.5e-03	0.024	NA	0.052	NA	0.079	8.3e-02	NA	2.0e-02	NA	4.9e-03
5	GTEx	Prostate	0.4530	0.1470	4.8e-03	0.039	NA	0.025	NA	-0.008	3.7e-02	NA	7.8e-02	NA	5.6e-01
6	GTEx	Testis	0.0810	0.0590	1.9e-03	0.023	NA	-0.003	NA	0.009	3.1e-02	NA	4.8e-01	NA	1.2e-01
7	GTEx	Thyroid	0.1170	0.0500	2.4e-05	0.040	NA	0.010	NA	0.023	4.4e-04	NA	4.9e-02	NA	6.5e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7
Respiratory disease	3.7	8.2	18.4	3.3	2.8	0.8	-4.3	-0.7	-3.0	-3.2
Average weekly fortified wine intake	3.5	4.1	9.6	0.4	2.1	-0.6	-1.6	-1.8	-3.1	-2.9
Hair/balding pattern: Pattern 2	3.4	4.3	8.5	2.5	2.9	0.2	-1.4	0.5	-2.6	-2.5
Hearing difficulty/problems: Yes	3.3	5.1	12.4	-1.3	-3.0	0.5	0.5	0.9	3.5	3.4
Forced expiratory volume in 1-second (FEV1)	3.3	11.0	37.6	-6.1	-3.4	-2.6	3.3	0.1	2.1	2.3
Shortness of breath walking on level ground	3.3	4.0	7.6	1.6	2.0	-0.3	-2.6	-0.6	-2.8	-2.6
Asthma (self-reported)	3.2	6.4	16.8	3.1	1.8	1.5	-4.1	-0.7	-2.4	-2.5
Lung FEV1/FVC ratio	3.0	15.2	22.8	-4.8	-4.4	-1.6	4.3	1.3	4.5	4.7
Systolic blood pressure, automated reading	3.0	8.7	24.6	3.8	5.0	1.4	-1.3	0.9	-3.1	-2.8
Asthma	3.0	5.8	16.0	3.0	1.5	1.6	-4.0	-0.6	-2.2	-2.4
Forced expiratory volume in 1-second (FEV1), Best measure	2.9	9.1	32.2	-5.7	-3.0	-2.2	3.1	-0.1	2.0	2.2
Pulse rate	2.7	4.6	12.2	-1.8	-3.5	0.1	-0.1	-1.1	2.9	2.6
Medication: Ventolin 100micrograms inhaler	2.7	3.5	7.8	2.8	2.4	0.4	-1.1	0.2	-2.1	-2.3
Medication: Metformin	2.6	3.7	10.8	-2.4	-1.8	0.4	-1.6	-3.3	1.2	1.3
Allergy	2.6	6.0	10.5	-3.0	-1.1	-0.2	3.2	1.1	3.1	3.2
Primary Biliary Cirrhosis	2.5	3.6	7.7	-0.0	-2.2	1.6	-1.8	-0.5	2.8	2.6
Systolic Blood Pressure	2.5	12.7	31.4	3.5	5.6	-0.8	-0.4	1.3	-4.5	-4.8
Ever had bowel cancer screening	2.4	2.9	6.0	1.2	0.8	2.0	2.5	2.1	1.2	1.5
Ever had prostate specific antigen (PSA) test	2.4	2.7	6.1	0.8	-0.3	1.4	2.5	1.3	2.2	2.0
Allergy or Eczema	2.3	6.1	14.3	2.0	1.6	-0.3	-3.8	-1.7	-3.0	-3.0
Medication: Amlodipine	2.3	3.2	8.9	2.3	3.0	1.7	-1.0	1.0	-1.5	-1.1
Mouth/teeth dental problems	2.2	3.3	6.5	1.2	2.3	-0.4	-1.6	-1.8	-2.1	-2.5
Chronic bronchitis/emphysema (mother)	2.2	2.6	8.2	-1.5	-1.2	-0.0	0.3	0.4	2.5	2.9
Breast cancer (self-reported)	2.2	2.6	6.5	-0.2	-0.2	0.9	2.5	1.5	2.3	1.9
Fed-up feelings	2.1	3.7	8.3	1.0	0.4	-2.5	-1.7	-0.8	-2.6	-2.9
Exposure to tobacco smoke outside home	2.1	2.7	9.6	-0.6	-0.6	1.6	-3.1	-2.0	0.7	1.3
Pulse rate, automated reading	2.1	6.9	20.0	-2.9	-4.5	0.3	-1.2	-0.7	3.1	3.0
Age at last live birth	1.9	2.8	6.2	-2.5	-2.1	-2.4	0.9	-0.9	1.2	0.5
Pain experienced in last month	1.9	3.2	8.3	-0.3	0.4	-2.3	-1.1	-0.7	-2.5	-2.9
Major Depression (MDD)	1.8	2.2	5.0	-1.6	-1.7	-0.8	-1.8	-2.2	0.5	0.4
Heart attack	1.8	2.3	4.4	-1.4	-0.7	-1.8	-1.2	-1.4	-1.6	-2.1
Alcohol drinker status: Never	1.8	2.1	4.9	-1.5	-2.2	-1.5	-1.3	-1.5	-0.5	-0.9
Breast Cancer	1.7	4.1	9.6	1.4	2.2	-1.7	0.1	0.6	-3.0	-3.1
Diverticular disease/diverticulitis (self-reported)	1.7	2.1	6.8	-0.2	-1.0	1.1	1.4	2.6	1.0	1.6
Qualifications: None of the above	1.7	3.6	8.7	3.0	2.0	1.8	-0.1	2.9	-1.0	-0.4
Birth weight	1.7	3.6	8.3	-0.3	-0.7	0.9	2.9	1.8	2.3	2.6
Medication for cholesterol	1.7	2.6	7.2	-1.5	-2.7	-1.7	0.8	-0.6	1.7	1.4
Medication: Gliclazide	1.7	2.0	6.4	-1.5	-0.2	-1.1	-1.1	-2.5	-1.0	-1.2
Depressed Affect (Nagel 2018)	1.6	3.4	7.8	1.3	0.8	-1.5	-1.8	-0.8	-2.8	-2.8
Falls in the last year	1.6	2.1	5.2	0.6	-1.8	0.1	2.3	1.5	1.4	1.4
Length of working week for main job	1.6	1.8	6.0	-0.3	0.2	1.2	2.5	1.6	1.2	0.8
Ever highly irritable/argumentative for 2 days	1.6	1.9	5.9	0.1	0.1	-0.7	-2.4	-1.1	-1.5	-1.9
Wheeze or whistling in the chest in last year	1.6	2.8	7.3	2.6	1.6	1.2	-2.7	-0.3	-0.8	-1.0
Age at first live birth	1.6	2.9	8.5	-2.9	-1.9	-1.5	1.7	0.3	1.3	1.1
Knee pain experienced in last month	1.6	2.5	7.6	-1.1	-0.7	1.1	-0.6	0.5	2.8	2.5
Loneliness, isolation	1.6	2.3	5.2	1.8	2.0	-0.5	2.3	0.9	-0.9	-1.1
Diabetes diagnosed by doctor	1.6	2.7	5.7	-2.4	-1.0	0.4	-2.0	-2.2	1.2	1.1
Eye problems/disorders: Cataract	1.6	1.9	7.6	-1.2	-0.7	-0.1	-2.8	-1.0	1.1	1.2
Osteoporosis (self-reported)	1.6	2.0	6.4	-0.3	-0.6	-0.2	2.5	0.7	1.9	1.6
Fractured/broken bones in last 5 years	1.6	2.1	4.5	-2.1	-2.1	-1.7	0.1	-1.2	0.9	0.6
Fasting Glucose	1.5	1.8	5.9	-1.1	-0.2	-0.4	-2.1	-2.4	-0.6	-0.7
Supplements: Zinc	1.5	1.6	3.9	-1.4	-1.5	-2.0	-0.6	-1.6	0.0	-0.1
Qualifications: CSEs or equivalent	1.5	1.9	5.5	2.0	2.4	0.8	0.7	0.8	-1.0	-1.2
Hayfever, allergic rhinitis or eczema	1.5	3.2	5.8	2.0	0.9	-0.3	-2.4	-1.3	-2.3	-2.3
Forced vital capacity (FVC)	1.5	5.8	26.8	-5.2	-2.1	-1.9	1.9	-0.2	1.1	1.3
Eye problems/disorders: None of the above	1.5	1.7	8.1	0.7	-0.4	0.2	2.8	1.8	-0.3	-0.5
Mouth/teeth dental problems: Loose teeth	1.5	1.8	6.0	-2.4	-1.5	-0.4	-1.4	-1.1	0.7	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.1	11.9	-2.3	-0.7	-1.8	3.4	0.7	0.3	0.6
Number of operations (self-reported)	1.5	2.3	5.6	-2.4	-1.7	0.1	-0.3	-0.7	1.5	2.1
Risk taking	1.5	2.2	5.2	-2.0	-0.0	-0.4	-1.9	-2.3	-1.1	-1.1
Heart attack/myocardial infarction (self-reported)	1.5	1.9	3.5	-1.4	-0.5	-1.3	-1.6	-1.3	-1.4	-1.9
Crohns Disease (2017)	1.4	3.0	9.7	0.9	-3.1	-0.2	-2.5	-2.0	0.4	0.2
Crohns Disease (2012)	1.4	2.3	6.8	-0.3	-2.6	0.3	-1.7	-2.4	0.1	0.6
Type 2 Diabetes (T2D) (2012)	1.4	1.6	5.5	0.2	-0.9	-0.2	-2.4	-2.1	-0.5	-0.5
Eye problems/disorders: Diabetes related eye disease	1.4	1.5	5.6	-1.0	0.4	-0.2	-2.4	-1.9	0.0	-0.2
Diabetes (father)	1.4	1.8	4.2	-0.4	-0.0	-1.3	-2.1	-1.3	-1.3	-1.7
High blood pressure (mother)	1.4	2.0	6.2	0.8	2.5	-0.7	1.4	0.9	-1.3	-1.5
Medication: Bendroflumethiazide	1.4	2.1	5.5	1.7	1.5	0.8	1.9	2.4	-0.2	-0.5
Cholesterol lowering medication	1.4	2.1	4.3	1.3	2.1	1.8	1.1	2.0	-0.6	-0.3
Serious illness, injury or assault to yourself	1.3	1.5	3.5	-0.2	-1.4	0.8	0.9	-0.8	1.8	1.9
Number of incorrect matches in round	1.3	2.1	5.1	-0.1	-1.2	0.7	1.7	0.9	2.1	2.3
Peak expiratory flow (PEF)	1.3	2.9	11.4	-3.4	-2.2	-1.6	0.8	-0.4	0.5	0.7
Osteoarthritis (self-reported)	1.3	1.7	3.5	-1.9	-1.9	-1.8	-0.5	-0.7	0.7	0.4
Medication: Blood pressure	1.3	2.5	7.8	0.9	2.8	0.9	0.7	0.7	-2.0	-1.8
Commuting to job workplace: Cycle	1.3	1.6	4.7	0.0	2.2	1.4	-0.0	0.8	1.2	1.5
Waist Hip Ratio (WHR)	1.2	5.5	12.0	-0.4	-1.0	2.5	2.5	1.4	3.5	3.3
Other serious medical condition/disability diagnosed by doctor	1.2	1.5	4.2	0.9	-0.1	1.6	-0.1	0.7	1.7	2.0
Hand grip strength (right)	1.2	3.2	9.9	-0.9	-0.6	-1.3	-3.1	-2.8	-1.1	-0.9
Maternal smoking around birth	1.2	1.8	5.9	0.3	0.4	-0.6	-2.0	-2.4	-0.9	-1.1
Medication: Levothyroxine sodium	1.2	2.1	10.0	0.7	-0.2	1.2	0.8	3.2	0.8	1.1
Qualifications: nursing, teaching	1.2	1.9	7.4	-2.7	-1.0	-1.4	0.5	-1.6	0.4	-0.0
Supplements: Calcium	1.2	1.3	2.6	-1.2	-1.6	-1.2	-0.1	-1.6	0.8	0.5
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	3.7	-1.2	-0.4	-1.3	0.9	-0.4	-1.9	-1.8
HbA1C	1.1	1.2	2.9	-1.4	-0.8	0.2	-0.8	-1.0	1.7	1.2
Cardiovascular Disease	1.1	3.5	8.0	1.7	2.8	0.7	2.1	1.7	-1.6	-1.8
Lung FVC	1.1	5.6	19.3	-3.8	-0.3	-1.2	4.4	0.7	1.2	1.5
Vitamin and mineral supplements	1.1	1.5	4.2	0.2	0.1	-1.2	-0.7	0.2	-2.0	-2.0
Diabetes (self-reported)	1.1	1.7	3.6	-1.8	-0.6	0.4	-1.9	-1.8	0.7	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	1.1	1.7	5.8	-2.4	-1.5	-1.6	1.0	-0.7	0.4	0.0
Headache pain in last month	1.1	1.9	4.2	0.7	-2.1	0.9	0.7	1.2	1.5	1.9
Number of full sisters	1.1	1.3	4.5	1.0	0.5	2.1	-1.7	-0.1	0.3	0.6
Average weekly red wine intake	1.1	1.6	4.1	-2.0	-2.0	-1.4	-0.2	-0.9	-0.2	-0.2
Handedness (chirality/laterality): Left-handed	1.1	1.3	3.5	-0.3	-0.6	0.5	0.5	-1.9	1.6	1.5
Back pain experienced in last month	1.1	1.6	4.0	2.0	1.3	1.4	0.2	1.9	-0.1	0.3
Miserableness	1.1	1.9	3.9	0.4	0.2	-1.4	-1.9	0.5	-2.0	-1.8
Diastolic blood pressure, automated reading	1.1	3.5	7.6	0.8	2.3	0.2	-2.8	-1.5	-2.3	-1.9
Medication: Omeprazole (e.g. Zanprol)	1.1	1.3	4.7	-2.2	-1.5	-1.1	-0.6	0.1	0.5	0.8
HDL Cholesterol	1.0	1.6	3.2	-0.8	0.7	0.7	1.6	0.9	1.8	1.8
LDL Cholesterol	1.0	1.6	6.1	-0.1	-1.4	0.3	1.1	-0.1	2.5	1.4
Triglycerides	1.0	1.7	4.9	0.6	-0.1	-0.9	-1.2	-0.1	-2.1	-2.2
Chronotype (morning person)	1.0	2.4	6.1	0.3	-1.1	-2.5	1.9	-0.3	-1.5	-1.8
Hand grip strength (left)	1.0	2.8	8.7	-0.4	-0.5	-1.4	-2.2	-3.0	-1.3	-1.2
Stomach or abdominal pain in last month	1.0	1.3	4.5	-1.5	-2.1	-0.5	-0.7	-1.0	0.6	0.6
Alcohol usually taken with meals	1.0	1.6	3.7	-1.9	-1.4	-0.9	0.7	-0.7	1.3	1.3
Qualifications: A levels/AS levels or equivalent	1.0	2.2	4.7	-2.2	0.0	-0.2	0.8	1.1	2.2	2.0
Illnesses of mother	1.0	1.2	4.1	-1.1	-0.6	-0.1	-2.0	-1.6	-0.4	-0.2
Forced vital capacity (FVC), Best measure	1.0	3.6	18.2	-4.3	-1.3	-1.2	1.6	-0.3	0.7	1.0
Emphysema/chronic bronchitis	1.0	1.2	3.6	1.9	1.2	-0.5	-0.8	-1.0	-0.5	-0.9
Neck or shoulder pain in last month	1.0	1.4	4.3	-1.4	-0.0	0.4	-2.1	-1.3	0.8	0.8
Heart disease (mother)	1.0	1.3	4.0	0.2	-1.4	0.1	2.0	0.9	1.1	0.8
Leg pain on walking	1.0	1.2	6.1	0.5	0.2	1.0	-2.5	-0.8	-0.5	-0.5
Wears glasses or contact lenses	1.0	1.1	2.6	0.4	0.4	0.9	-1.6	0.5	1.4	1.4
Ever taken oral contraceptive pill	1.0	1.1	3.5	-1.3	-1.9	-0.1	-0.8	-1.0	0.9	0.3
High cholesterol (Self-reported)	1.0	1.7	3.8	1.6	1.9	1.5	0.9	1.4	-0.5	-0.4
Mean Putamen Volume	0.9	1.0	2.5	0.7	1.6	0.2	1.2	1.5	-0.6	-0.5
Blood Eosinophil Count	0.9	6.5	18.1	1.4	3.2	0.0	-4.2	-2.5	-2.2	-2.1
Townsend deprivation index at recruitment	0.9	1.3	3.9	1.6	1.3	0.6	-2.0	-0.4	-0.0	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	3.9	-0.0	-0.0	-1.1	-1.3	-2.0	-0.7	-1.1
Relative age voice broke	0.9	1.4	2.6	-1.1	0.2	-1.1	-0.8	-1.6	-1.5	-1.5
Tinnitus: Yes, but not now, but have in the past	0.9	1.0	2.2	-0.7	0.5	0.0	1.2	1.0	1.5	1.2
Hayfever/allergic rhinitis (self-reported)	0.9	1.1	2.7	1.6	1.1	0.4	-0.8	-0.5	-1.2	-1.3
Medication: Simvastatin	0.9	1.4	3.1	1.6	1.0	1.5	0.8	1.8	0.0	0.0
Hair/balding pattern: Pattern 3	0.9	1.3	2.1	-1.3	-1.4	-1.1	1.5	-0.6	0.9	0.9
Happiness	0.9	1.1	3.3	-0.2	-0.9	0.3	0.5	-0.3	1.8	1.8
Depression (self-reported)	0.9	1.0	3.8	-2.0	-0.9	-0.9	-0.2	-1.0	0.8	0.4
Prospective memory result	0.9	1.1	1.6	0.5	1.2	1.0	-0.6	-1.2	-1.3	-1.2
Exposure to tobacco smoke at home	0.9	1.0	5.6	0.1	-0.6	0.8	-2.4	-0.5	0.5	0.1
Birth weight of first child	0.9	1.7	5.6	-1.3	-2.4	-1.4	1.0	0.1	1.0	0.7
Mouth/teeth dental problems: Bleeding gums	0.9	1.2	3.0	0.5	-1.0	0.7	1.6	1.7	0.5	0.9
Comparative body size at age 10	0.9	2.5	9.5	-0.1	-0.1	0.6	3.1	1.4	1.6	1.9
Angina (self-reported)	0.9	1.2	5.3	-1.0	-0.2	1.1	-2.3	-0.9	0.1	-0.1
Medication: Omeprazole	0.9	1.1	2.8	-1.7	-1.3	-1.1	-1.0	-0.9	-0.4	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	3.4	1.8	0.9	0.2	-1.2	-0.6	-0.5	-1.2
Hypertension (Self-reported)	0.9	2.4	7.6	1.5	2.8	1.5	0.4	0.7	-1.4	-1.4
Friendships satisfaction	0.9	1.2	2.8	-0.7	-1.0	0.3	0.3	1.0	1.7	1.7
Commuting to job workplace: Walk	0.9	1.0	2.9	-1.3	-0.7	-1.2	-0.8	-1.7	-0.0	-0.2
Pain type(s) experienced in last month: Hip pain	0.9	1.2	2.4	-1.5	-1.2	-0.7	1.4	0.4	0.9	0.9
Unable to work because of sickness or disability	0.9	1.1	3.0	0.9	0.6	0.6	1.7	1.3	0.8	0.8
Pack years of smoking	0.9	1.4	4.4	0.4	-0.4	1.7	-2.1	-0.7	0.7	1.0
Alzheimer’s Disease (in father)	0.8	0.8	4.2	-0.7	-0.3	-0.3	-0.9	-2.0	0.2	-0.1
Rheumatoid Arthritis	0.8	1.1	4.4	0.2	-0.2	-0.2	2.1	1.7	0.3	0.3
Type 2 Diabetes (T2D) (2018)	0.8	1.4	5.9	-1.4	-0.9	-0.1	-1.2	-2.4	0.2	-0.1
Ever used hormone-replacement therapy (HRT)	0.8	1.0	3.6	-0.8	-0.4	0.3	0.8	1.9	0.8	0.9
Had menopause	0.8	0.9	1.7	1.3	1.2	1.1	-0.5	1.0	0.6	0.8
Financial difficulties in last 2 years	0.8	1.0	2.6	0.3	-1.4	-1.6	0.8	0.0	-0.8	-1.1
Pain all over the body in last month	0.8	0.8	2.4	1.2	-0.3	1.5	0.9	0.2	0.6	0.9
Worrier / anxious feelings	0.8	1.5	3.4	-1.1	-1.9	0.4	0.5	0.6	1.5	1.8
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.4	5.2	1.7	-0.4	-0.2	-2.3	-0.0	-0.7	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	2.3	1.5	0.5	1.5	-0.5	-0.9	0.7	0.5
Blood clot in the leg (DVT)	0.8	1.0	2.5	-1.2	-0.3	-0.8	0.8	-0.2	-1.6	-1.4
Number of full brothers	0.8	1.1	2.6	-0.3	-0.3	1.5	-0.3	-0.0	1.6	1.5
Health satisfaction	0.8	1.0	3.2	-0.4	-1.0	-0.6	-1.8	-1.1	-0.8	-0.9
Long-standing illness, disability or infirmity	0.8	1.3	4.5	0.1	0.2	0.2	-2.1	-1.1	-1.3	-1.2
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.8	2.8	-0.9	-0.4	-1.7	0.7	-1.0	-0.4	-0.6
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	2.9	-0.7	-0.1	0.8	1.7	0.9	1.4	1.7
Bipolar Disorder (2011)	0.7	0.6	2.3	0.1	0.1	0.0	-1.5	-1.4	-0.2	-0.0
Lupus	0.7	1.1	3.1	-0.5	-1.1	-0.4	0.4	0.7	1.8	1.6
Angina	0.7	1.0	4.2	-0.8	0.0	1.2	-2.0	-0.6	-0.2	-0.3
Severe depression (siblings)	0.7	0.8	1.9	1.4	0.4	1.4	0.3	1.0	0.2	0.5
Pack years adult smoking proportion	0.7	1.1	4.3	0.3	-0.4	1.4	-2.1	-0.9	0.6	0.7
Multivitamins +/- minerals	0.7	0.9	1.9	-0.6	0.7	1.1	-0.6	-0.6	1.4	1.4
Alcohol intake versus 10 years previously	0.7	1.0	2.3	0.7	-0.9	0.9	1.5	-0.7	1.2	0.9
Number of live births	0.7	1.1	2.2	-1.4	-1.0	-1.5	0.1	-0.9	-0.7	-0.9
Noisy workplace	0.7	0.9	2.5	0.1	0.0	0.9	-1.6	-1.6	-0.5	-0.3
Loud music exposure frequency	0.7	0.8	2.8	-1.3	-0.4	0.2	-0.3	-1.7	0.8	0.6
Worry too long after embarrassment	0.7	1.2	2.6	1.3	1.6	0.8	0.7	1.5	-0.7	-0.7
Medication for pain relief, constipation, heartburn	0.7	1.1	3.0	-0.0	0.4	-1.4	0.7	-0.4	-1.5	-1.7
Migraine (self-reported)	0.7	0.9	2.2	-0.7	0.7	1.1	-1.5	-1.0	0.3	0.8
Medication: Seretide 50 evohaler	0.7	0.8	2.3	1.5	0.9	0.9	-0.4	0.9	-0.4	-0.5
Average weekly champagne plus white wine intake	0.7	0.9	4.2	-0.5	0.1	0.6	-1.1	-2.0	-0.6	-0.2
Mother’s age at death	0.7	0.9	2.0	0.7	1.4	-0.3	-0.1	1.2	-1.0	-1.0
Eye problems/disorders: Glaucoma	0.7	0.8	3.0	0.3	1.2	0.4	-1.7	0.0	-0.9	-0.5
Medication: Paracetamol	0.7	1.0	3.6	-0.8	-1.9	-0.3	-0.6	0.2	1.0	1.1
Medication: Atorvastatin	0.7	0.8	3.8	-1.9	-0.5	0.3	-0.0	0.5	0.8	0.8
Average weekly beer plus cider intake	0.7	1.0	5.1	0.2	0.3	-0.0	-2.3	-1.2	-0.6	-0.5
Basal cell carcinoma (self-reported)	0.7	0.8	1.8	0.8	-0.9	0.3	0.5	-0.2	1.4	1.3
Neuroticism (Nagel 2018)	0.6	1.4	3.4	1.2	1.0	-0.6	-0.7	0.5	-1.8	-1.6
Schizophrenia vs Biploar Disorder	0.6	0.8	2.0	1.4	1.0	-0.2	-1.0	0.2	-1.0	-0.8
Irritable Bowel Disease (IBD)	0.6	1.4	5.7	0.3	-2.4	-1.1	-1.1	-1.2	0.7	0.2
Coronary Artery Disease (CAD)	0.6	0.7	2.4	-0.2	-0.1	-0.4	-1.6	-1.3	0.1	-0.7
Leg fat-free mass (left)	0.6	3.3	9.6	-2.8	-1.6	-0.1	-3.1	-1.2	0.7	0.9
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	3.0	-1.7	-0.4	-0.8	-0.7	-0.1	-0.7	-0.5
Leg predicted mass (left)	0.6	3.3	9.8	-2.8	-1.5	-0.1	-3.1	-1.2	0.7	0.9
Waist circumference	0.6	2.3	4.8	-1.3	-1.1	2.2	-0.9	0.3	1.6	2.2
Weight	0.6	3.0	7.6	-2.8	-1.9	0.7	-2.2	-0.8	1.2	1.7
Father’s age at death	0.6	0.8	1.7	-0.4	-1.1	-0.9	1.3	0.6	0.6	1.0
Lung cancer (father)	0.6	0.7	1.4	1.1	0.1	0.1	0.1	-1.0	-1.2	-1.0
Breastfed as a baby	0.6	0.7	2.0	-0.3	0.4	0.8	0.3	0.8	1.1	1.4
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	1.9	-0.5	-0.3	0.9	0.5	0.6	1.1	1.4
Mean time to correctly identify matches	0.6	1.1	2.7	-1.2	-1.6	-1.1	1.1	0.7	0.3	0.6
Comparative height size at age 10	0.6	3.5	9.1	-2.3	-0.7	2.0	-1.0	0.4	2.1	3.0
Overall health rating	0.6	1.2	3.6	1.9	0.2	1.8	-1.1	0.1	0.5	0.6
Illnesses of siblings: Diabetes	0.6	0.8	1.3	-0.9	-1.0	0.2	-0.1	-1.1	1.1	1.0
Smoking status: Previous	0.6	0.9	3.3	-0.5	0.1	0.3	1.8	1.4	0.6	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	2.0	0.3	-0.7	-0.7	1.4	1.4	-0.2	0.2
Smoking status: Current	0.6	0.9	4.3	2.1	0.5	0.6	-0.9	-0.7	0.2	-0.2
Hearing aid user	0.6	0.7	1.7	1.2	1.0	1.3	-0.1	0.5	0.5	0.6
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.4	0.6	-0.2	0.1	-0.6	-0.2	-1.6	-1.2
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.2	-0.9	-0.3	0.2	1.5	0.9	0.7	1.2
Irritability	0.6	0.9	2.9	-0.1	-1.7	0.3	-1.0	0.0	1.0	1.3
Myopia	0.6	0.8	2.4	1.2	0.2	0.4	1.1	1.6	-0.4	-0.3
Vascular/heart problems diagnosed by doctor	0.6	1.7	5.1	-1.0	-2.3	-1.1	-0.4	-0.6	1.4	1.5
Depression (Nagel 2018)	0.5	0.8	1.8	0.6	0.6	-0.6	-1.1	-0.5	-1.1	-1.4
Neuroticism (2016)	0.5	0.7	1.3	0.6	-0.5	-0.8	0.2	1.1	-1.0	-1.0
Heel T-Score	0.5	4.4	6.9	2.4	1.5	1.1	2.6	2.5	-2.1	-1.8
Diabetes (mother)	0.5	0.7	2.6	1.0	-1.0	-0.1	1.6	0.4	0.2	0.1
Current tobacco smoking	0.5	0.8	4.2	2.1	0.5	0.6	-0.5	-0.4	0.4	-0.1
High blood pressure	0.5	1.5	4.4	0.9	2.1	1.0	1.0	0.9	-1.0	-1.0
Supplements: Glucosamine	0.5	0.7	1.2	-0.8	-0.6	-1.0	-1.1	-1.1	-0.4	-0.4
Sitting height	0.5	3.4	7.3	-2.7	-2.4	0.5	-2.2	-0.5	1.4	1.9
Chronic bronchitis/emphysema (father)	0.5	0.6	3.1	0.6	1.8	0.1	-0.1	-0.8	-0.3	-0.5
Trunk fat mass	0.5	2.3	4.9	-2.2	-1.6	1.1	-1.5	-0.5	1.2	1.8
Hip circumference	0.5	2.2	6.3	-2.0	-1.4	0.9	-2.5	-0.9	0.4	1.0
Time employed in main current job	0.5	0.5	1.3	0.8	0.5	1.1	0.3	0.1	0.8	0.9
Mouth/teeth dental problems: Dentures	0.5	0.8	2.1	-0.6	-1.4	-0.9	0.7	1.0	0.6	0.6
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	2.7	0.6	1.0	0.1	-1.6	-0.8	-0.1	-0.0
Standing height	0.5	4.7	14.1	-3.8	-2.1	0.1	-2.0	-0.5	2.0	2.5
Pulse wave peak to peak time	0.5	0.6	1.6	-0.8	-1.2	-1.1	0.7	-0.6	0.4	0.4
Had major operations	0.5	0.6	1.6	-0.5	0.6	0.5	0.7	0.6	1.0	1.3
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.5	1.9	0.2	1.0	0.2	0.5	-1.4	0.6	0.4
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	3.1	-1.8	0.2	-0.9	-0.7	0.2	-0.1	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.9	-1.4	0.6	-0.8	-1.1	-0.1	0.1	-0.0
Illnesses of father: Heart disease	0.5	0.7	2.6	-1.2	-0.8	-0.2	-0.4	-1.6	0.5	0.1
Whole body fat-free mass	0.5	2.6	7.8	-2.4	-1.4	0.1	-2.8	-0.9	0.7	1.0
Leg fat-free mass (right)	0.5	2.9	10.8	-2.3	-1.3	0.1	-3.3	-1.4	0.4	0.6
Mood swings	0.5	0.9	3.2	-1.3	-1.8	-0.9	-0.4	-0.4	0.6	0.5
Leg predicted mass (right)	0.5	2.9	10.6	-2.3	-1.3	0.1	-3.3	-1.3	0.5	0.7
Medication: Lisinopril	0.5	0.6	2.1	0.5	0.7	0.4	1.0	1.5	-0.1	-0.5
Basal metabolic rate	0.5	2.7	6.6	-2.6	-1.6	0.2	-2.6	-0.8	0.9	1.2
Intelligence (Savage-Jansen 2018)	0.4	1.2	4.5	-2.1	0.6	0.2	-0.4	-1.4	0.6	0.8
Alzheimer’s Disease (in mother)	0.4	0.5	1.3	-1.0	-0.1	-1.1	0.5	0.8	-0.3	-0.5
Reaction Time	0.4	0.7	1.7	-0.7	-1.2	-0.9	1.3	0.7	-0.2	0.2
Prostate Cancer	0.4	0.6	1.3	-0.9	-0.0	1.0	-1.1	-0.8	0.5	0.6
Height	0.4	8.2	23.8	-4.9	-2.6	-0.5	-3.4	-1.9	2.2	2.7
Neuroticism	0.4	1.0	1.5	1.0	0.8	-0.6	-0.6	1.2	-1.2	-1.1
Frequency of depressed mood in last 2 weeks	0.4	0.5	1.2	-0.4	-1.1	-0.1	0.3	-0.2	1.1	0.9
Impedance of leg (right)	0.4	2.1	12.4	0.2	0.1	0.1	3.5	1.2	0.5	0.5
Taking other prescription medications	0.4	0.6	2.0	0.2	-1.4	0.1	-1.3	0.4	-0.1	0.3
Medication: Atenolol	0.4	0.5	1.2	-0.5	-0.8	0.1	1.1	0.8	0.8	0.4
Impedance of leg (left)	0.4	2.1	12.4	1.0	0.2	0.4	3.5	1.0	0.3	0.3
Past tobacco smoking	0.4	0.6	2.3	0.4	0.2	-0.1	-1.5	-0.6	-1.1	-0.7
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	1.9	0.0	-0.8	-0.2	-1.4	-1.0	0.6	0.3
Impedance of arm (right)	0.4	2.0	4.6	-1.0	-0.4	0.3	1.9	0.9	2.2	2.0
Arm fat percentage (right)	0.4	1.5	3.0	-1.7	-1.2	1.0	-0.6	0.2	1.3	1.7
Trunk fat-free mass	0.4	2.4	6.2	-2.5	-1.6	-0.0	-2.2	-0.5	1.1	1.4
Arm fat mass (right)	0.4	1.7	4.0	-2.0	-1.4	0.9	-1.4	-0.1	1.0	1.5
Trunk predicted mass	0.4	2.4	5.9	-2.4	-1.6	-0.0	-2.2	-0.5	1.1	1.4
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.3	-0.3	1.0	-0.1	-1.5	-0.6	-0.6	-0.7
Medication: Paracetamol	0.4	0.7	2.1	0.1	-1.1	0.2	-0.1	0.1	1.4	1.4
Glaucoma (self-reported)	0.4	0.5	1.6	-0.5	0.5	-0.1	-1.3	-0.7	-0.8	-0.5
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	3.8	0.4	0.1	0.8	-0.2	1.9	0.4	0.7
Number of children fathered	0.4	0.4	1.6	-1.3	0.3	-0.2	-0.0	-0.5	-0.7	-0.7
Medication: Ibuprofen	0.4	0.5	2.5	-0.5	-0.2	-0.5	-1.6	-0.7	0.2	0.2
Whole body fat mass	0.4	1.6	3.6	-1.9	-1.3	1.2	-1.5	-0.3	0.7	1.3
Leg fat mass (right)	0.4	1.4	4.2	-2.1	-1.7	0.6	-0.9	-0.4	0.5	0.9
Arm predicted mass (right)	0.4	2.1	9.5	-1.7	-1.0	-0.0	-3.1	-1.2	-0.2	0.2
Chest pain or discomfort	0.4	0.5	2.3	0.9	-0.3	1.5	-0.2	0.4	0.3	0.4
Family relationship satisfaction	0.4	0.5	1.7	1.3	0.3	0.5	0.1	1.0	0.4	0.7
Supplements: Vitamin C	0.4	0.5	0.8	-0.5	-0.9	-0.6	0.9	0.5	0.7	0.6
Illnesses of father: None of the above (group 1)	0.4	0.5	1.7	0.5	-0.8	0.1	-0.4	1.3	0.4	0.8
Whole body water mass	0.4	2.4	7.6	-2.3	-1.4	0.1	-2.8	-0.8	0.7	1.0
Arm fat mass (left)	0.4	1.7	4.0	-2.0	-1.4	0.7	-1.6	-0.4	0.9	1.3
Ever smoked	0.4	0.7	2.3	0.1	0.3	0.2	1.5	0.2	1.3	0.7
Arm fat-free mass (left)	0.4	1.8	5.2	-1.9	-1.5	0.3	-2.3	-0.9	0.5	0.8
Ever depressed for a whole week	0.4	0.5	1.1	-0.6	-1.1	-0.4	-0.2	0.5	1.1	0.7
Arm predicted mass (left)	0.4	1.8	5.2	-1.9	-1.5	0.4	-2.3	-0.7	0.7	0.9
Bipolar Disorder (2018)	0.3	0.5	0.9	-1.0	-0.9	-0.0	-0.3	0.1	0.8	0.9
Alzheimer’s Disease (including proxy)	0.3	0.4	1.2	-1.1	-0.5	-1.0	0.4	0.0	-0.1	-0.6
Ulcerative Colitis (UC)	0.3	0.6	2.1	0.0	-1.0	-1.5	0.6	-0.6	0.8	0.1
Age at First Birth	0.3	0.5	1.5	-1.2	-0.6	-0.7	0.1	-0.8	-0.2	-0.2
Schizophrenia (2014)	0.3	0.7	2.0	-0.5	0.9	0.4	-0.9	-1.4	0.5	0.5
Ulcerative Colitis	0.3	0.4	1.7	-0.0	-0.4	0.0	1.3	0.8	0.8	0.3
Average weekly spirits intake	0.3	0.4	1.0	0.7	-0.4	-0.2	-0.5	-0.1	-1.0	-0.8
Sensitivity / hurt feelings	0.3	0.5	1.5	-0.6	-0.7	-0.6	1.2	0.8	0.1	0.1
Ever had hysterectomy (womb removed)	0.3	0.4	1.6	-1.3	0.7	0.0	0.1	0.5	0.3	0.6
Medication for hormone replacement therapy	0.3	0.3	1.2	-0.1	-0.2	0.9	-1.1	-0.3	0.0	0.2
Medication: Co-codamol	0.3	0.4	0.7	-0.8	-0.5	-0.6	-0.8	-0.2	-0.7	-0.5
Trunk fat percentage	0.3	1.4	3.0	-1.7	-1.3	1.1	-0.8	-0.4	0.9	1.5
Nervous feelings	0.3	0.6	1.9	-1.1	0.0	-0.8	-0.1	1.4	0.1	-0.1
Hearing difficulty/problems with background noise	0.3	0.5	1.9	-0.1	-0.7	-0.2	0.9	1.4	0.4	0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	2.0	0.1	0.5	-0.1	1.4	1.3	-0.7	-0.6
Medication: Ramipril	0.3	0.4	1.1	-0.7	0.1	-0.5	-0.0	-0.3	-0.9	-1.1
Illnesses of siblings	0.3	0.4	1.8	1.3	0.7	0.2	0.4	0.6	-0.2	-0.1
Pulse wave Arterial Stiffness index	0.3	0.4	0.9	0.4	0.9	0.7	-0.9	0.4	-0.2	-0.3
Tense / ‘highly strung’	0.3	0.5	1.0	-1.0	-0.2	0.2	1.0	0.7	0.8	0.8
Hair/balding pattern: Pattern 4	0.3	0.6	1.5	0.8	-0.3	1.0	-1.2	-0.4	-0.8	-0.6
Pulse wave reflection index	0.3	0.4	1.2	-0.0	1.1	-0.4	-0.2	-0.2	-0.9	-0.8
Gout (self-reported)	0.3	0.4	1.1	0.2	0.8	-0.3	0.2	-1.0	-0.6	-0.9
Body fat percentage	0.3	1.2	2.6	-1.6	-1.3	1.1	-0.7	-0.3	0.7	1.3
Leg fat percentage (right)	0.3	0.9	2.4	-1.5	-1.6	0.7	0.4	-0.1	0.5	1.0
Arm fat-free mass (right)	0.3	1.7	7.7	-1.6	-1.0	0.0	-2.8	-0.9	-0.3	0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	0.7	0.8	0.8	-0.0	0.3	-0.1	-0.7	-0.8
Qualifications: College or University degree	0.3	1.0	1.9	-1.4	-0.8	-0.7	0.9	1.0	1.2	0.8
Medication: Allopurinol	0.3	0.4	1.4	-1.0	-0.1	-0.3	0.3	-1.2	-0.3	-0.3
Alcohol intake frequency.	0.3	0.7	2.0	-0.4	-1.4	-0.6	0.1	-1.4	-0.2	-0.7
Suffer from ‘nerves’	0.3	0.4	1.1	0.8	1.1	-0.1	-0.5	0.5	-0.7	-0.6
Arm fat percentage (left)	0.3	1.1	2.6	-1.6	-1.0	0.9	-1.0	-0.1	0.9	1.4
Number of self-reported non-cancer illnesses	0.3	0.5	1.6	0.3	0.5	1.2	-1.3	0.4	-0.0	0.1
Illnesses of father: High blood pressure	0.3	0.3	1.5	-0.2	0.7	-0.0	1.2	-0.3	0.4	0.1
Leg fat mass (left)	0.3	1.2	2.6	-1.6	-1.6	0.9	-1.0	-0.5	0.5	0.9
Worry (Nagel 2018)	0.2	0.3	1.2	0.5	0.3	-0.0	-0.2	1.1	-0.8	-0.6
Ovarian Cancer	0.2	0.3	0.8	0.3	0.0	-0.1	-0.8	-0.9	-0.4	-0.3
Blood White Count	0.2	1.3	7.0	0.4	0.0	0.5	-2.6	-1.2	-0.0	-0.2
BMI	0.2	1.2	3.0	-1.2	-1.7	-0.9	-0.9	-1.0	-1.0	-0.8
Number of treatments/medications taken	0.2	0.3	1.1	0.7	-0.1	1.1	-0.1	0.3	0.4	0.5
Relative age of first facial hair	0.2	0.5	2.0	-1.4	-0.3	-0.2	-0.6	-0.8	0.3	0.2
Age when periods started (menarche)	0.2	0.6	1.7	0.0	-1.3	-1.2	-0.0	-0.5	0.1	-0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.4	1.2	-0.3	-0.3	-0.4	1.0	1.1	-0.6	-0.4
Body mass index (BMI)	0.2	0.7	1.7	-1.1	-1.0	0.7	-1.3	-0.4	0.3	0.6
Had other major operations	0.2	0.3	0.9	-0.5	-0.3	0.9	0.1	0.3	0.4	0.6
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.5	0.6	0.0	0.5	-0.3	0.4	0.7	0.6
Neuroticism score	0.2	0.4	0.9	0.4	0.5	-0.7	-0.3	1.0	-0.7	-0.7
Medication: Lansoprazole	0.2	0.3	0.5	-0.5	0.7	0.1	0.5	-0.5	-0.6	-0.5
Impedance of arm (left)	0.2	1.1	2.8	-0.9	0.0	0.2	1.1	0.5	1.6	1.7
Medication for cholesterol, blood pressure or diabetes	0.2	0.4	1.4	0.3	0.7	-0.1	-1.2	0.1	-0.7	-0.3
Commuting to job workplace: Car/motor vehicle	0.2	0.2	0.9	-0.1	-0.6	0.2	0.1	-0.0	-0.9	-0.6
Medication: Aspirin	0.2	0.3	1.5	-0.1	-0.6	1.2	-0.3	0.0	0.4	0.5
Mineral and other dietary supplements	0.2	0.3	0.9	0.6	0.9	0.3	-0.4	0.2	-0.6	-0.6
Medication: Aspirin	0.2	0.3	0.8	-0.5	-0.9	0.8	-0.5	-0.0	0.3	0.2
Guilty feelings	0.2	0.4	0.9	-0.9	-0.2	-0.5	-0.4	-0.5	0.7	0.7
Financial situation satisfaction	0.2	0.2	0.5	-0.7	-0.7	-0.3	-0.3	-0.3	0.5	0.3
Commuting to job workplace: Public transport	0.2	0.3	1.1	-0.4	1.1	0.1	-0.4	0.3	0.4	0.3
Leg fat percentage (left)	0.2	0.8	2.3	-0.9	-1.5	1.1	0.1	-0.3	0.5	0.9
Impedance of whole body	0.2	0.9	4.4	-0.1	0.2	0.3	2.1	0.6	0.8	0.8
Bipolar Disorder or Schizophrenia	0.1	0.2	0.3	-0.3	0.1	0.4	0.2	-0.3	0.6	0.6
Schizophrenia (2018)	0.1	0.2	0.7	0.3	0.9	0.5	0.5	-0.4	0.1	0.0
Verbal and Numeric Reasoning (VNR)	0.1	0.3	0.7	-0.8	0.7	0.6	-0.7	0.2	-0.2	0.1
Body Mass Index (BMI) (2010)	0.1	0.2	0.8	-0.1	-0.9	-0.2	-0.3	-0.3	0.0	0.2
Blood Platelet Count	0.1	0.9	3.6	0.8	1.1	0.8	1.9	-0.5	0.4	-0.3
Blood Red Count	0.1	0.7	1.5	-0.8	-1.2	0.2	-0.7	-0.3	1.1	0.7
Smoking Status	0.1	0.3	1.1	1.1	0.1	0.0	0.0	0.8	0.6	-0.0
Hypothyroidism (self reported)	0.1	0.3	0.7	-0.1	-0.7	-0.8	-0.2	0.8	-0.2	-0.4
Hair Pigment	0.1	2.4	8.5	-0.9	1.1	0.2	-2.9	-2.2	-1.0	-0.5
Tanning	0.1	1.6	7.5	2.7	0.6	0.3	1.1	0.2	-1.1	-1.1
Fluid intelligence score	0.1	0.2	1.2	-1.1	-0.1	-0.0	-0.6	-0.2	-0.3	-0.2
Medication: Cholesterol lowering	0.1	0.1	0.5	-0.1	-0.3	0.7	0.1	0.0	0.3	0.3
High blood pressure (siblings)	0.1	0.1	0.6	-0.3	0.8	0.1	-0.4	0.0	-0.3	-0.2
Medication: Blood pressure	0.1	0.1	0.2	-0.1	-0.4	-0.5	0.2	-0.3	0.2	-0.4
Age started oral contraceptive pill	0.1	0.2	0.5	0.3	-0.2	-0.1	0.7	0.5	0.2	0.4
Heart disease (siblings)	0.1	0.1	0.4	-0.1	-0.3	0.7	-0.7	-0.1	-0.1	-0.0
Alcohol drinker status: Previous	0.1	0.1	0.2	-0.3	-0.1	-0.0	-0.2	-0.5	0.4	0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.2	-0.4	0.1	0.1	-0.5	-0.5	-0.0	-0.0

Hub : Genes

DNAJC9-AS1

Models

Trait associations