[Hub]/) : Traits : Forced vital capacity (FVC) : ← →

chr2:35,883,253-37,567,226

Best TWAS P=1.79e-12 · Best GWAS P=1.31e-11 conditioned to 0.509

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FEZ2	0.16	0.24	lasso	2	0.22	1.3e-26	6.0	-6.0	1.5e-09	0.48	0.18	0.82	FALSE
2	GTEx	Adipose Subcutaneous	AC007401.1	0.10	0.02	lasso	4	0.02	5.4e-03	5.5	6.1	1.4e-09	-0.41	0.28	0.43	FALSE
3	GTEx	Artery Tibial	CRIM1	0.10	0.04	lasso	4	0.05	1.4e-04	5.5	-6.8	1.3e-11	0.54	0.14	0.81	FALSE
4	GTEx	Artery Tibial	RP11-78I14.1	0.10	0.08	enet	16	0.07	4.2e-06	5.5	-6.9	4.8e-12	0.58	0.27	0.60	FALSE
5	GTEx	Brain Cerebellar Hemisphere	FEZ2	0.41	0.30	lasso	6	0.28	8.6e-08	5.2	5.2	2.3e-07	-0.48	0.61	0.27	FALSE
6	GTEx	Brain Cerebellar Hemisphere	RP11-490M8.1	0.37	0.18	lasso	4	0.15	1.2e-04	5.1	5.2	2.4e-07	-0.48	0.23	0.19	FALSE
7	GTEx	Skin Sun Exposed Lower leg	RP11-78I14.1	0.14	0.06	enet	8	0.04	6.0e-04	-6.6	-5.6	2.3e-08	0.76	0.01	0.98	FALSE
8	GTEx	Spleen	FEZ2	0.42	0.16	enet	25	0.17	3.9e-05	5.0	6.0	2.0e-09	-0.46	0.24	0.32	FALSE
9	GTEx	Whole Blood	AC007401.1	0.06	0.06	lasso	5	0.05	4.6e-05	5.2	5.2	2.1e-07	-0.48	0.69	0.12	FALSE
10	NTR	Blood	CRIM1	0.09	0.10	lasso	6	0.11	3.1e-32	5.8	-5.7	1.6e-08	0.53	0.73	0.27	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	FEZ2	0.41	0.55	lasso	5	0.58	3.1e-93	5.2	-5.6	2.5e-08	0.50	0.89	0.11	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	FEZ2	0.01	0.01	blup	85	0.01	1.0e-03	5.2	-6.7	2.0e-11	0.63	0.15	0.55	FALSE
13	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	FEZ2	0.06	0.05	lasso	4	0.04	3.3e-03	5.7	-5.4	5.3e-08	0.47	0.17	0.19	FALSE
14	The Cancer Genome Atlas	Prostate Adenocarcinoma	FEZ2	0.06	0.05	blup	87	0.08	1.4e-08	5.2	-5.4	8.1e-08	0.45	0.75	0.25	FALSE
15	The Cancer Genome Atlas	Testicular Germ Cell Tumors	FEZ2	0.18	0.21	lasso	6	0.21	5.3e-08	-6.6	-7.0	1.8e-12	0.92	0.01	0.99	TRUE