[Hub]/) : Traits : Forced vital capacity (FVC) :

chr2:35,883,253-37,567,226

Best TWAS P=1.79e-12 · Best GWAS P=1.31e-11 conditioned to 0.509

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FEZ2 0.16 0.24 lasso 2 0.22 1.3e-26 6.0 -6.0 1.5e-09 0.48 0.18 0.82 FALSE
2 GTEx Adipose Subcutaneous AC007401.1 0.10 0.02 lasso 4 0.02 5.4e-03 5.5 6.1 1.4e-09 -0.41 0.28 0.43 FALSE
3 GTEx Artery Tibial CRIM1 0.10 0.04 lasso 4 0.05 1.4e-04 5.5 -6.8 1.3e-11 0.54 0.14 0.81 FALSE
4 GTEx Artery Tibial RP11-78I14.1 0.10 0.08 enet 16 0.07 4.2e-06 5.5 -6.9 4.8e-12 0.58 0.27 0.60 FALSE
5 GTEx Brain Cerebellar Hemisphere FEZ2 0.41 0.30 lasso 6 0.28 8.6e-08 5.2 5.2 2.3e-07 -0.48 0.61 0.27 FALSE
6 GTEx Brain Cerebellar Hemisphere RP11-490M8.1 0.37 0.18 lasso 4 0.15 1.2e-04 5.1 5.2 2.4e-07 -0.48 0.23 0.19 FALSE
7 GTEx Skin Sun Exposed Lower leg RP11-78I14.1 0.14 0.06 enet 8 0.04 6.0e-04 -6.6 -5.6 2.3e-08 0.76 0.01 0.98 FALSE
8 GTEx Spleen FEZ2 0.42 0.16 enet 25 0.17 3.9e-05 5.0 6.0 2.0e-09 -0.46 0.24 0.32 FALSE
9 GTEx Whole Blood AC007401.1 0.06 0.06 lasso 5 0.05 4.6e-05 5.2 5.2 2.1e-07 -0.48 0.69 0.12 FALSE
10 NTR Blood CRIM1 0.09 0.10 lasso 6 0.11 3.1e-32 5.8 -5.7 1.6e-08 0.53 0.73 0.27 FALSE
11 ROSMAP Brain Pre-frontal Cortex FEZ2 0.41 0.55 lasso 5 0.58 3.1e-93 5.2 -5.6 2.5e-08 0.50 0.89 0.11 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma FEZ2 0.01 0.01 blup 85 0.01 1.0e-03 5.2 -6.7 2.0e-11 0.63 0.15 0.55 FALSE
13 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FEZ2 0.06 0.05 lasso 4 0.04 3.3e-03 5.7 -5.4 5.3e-08 0.47 0.17 0.19 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma FEZ2 0.06 0.05 blup 87 0.08 1.4e-08 5.2 -5.4 8.1e-08 0.45 0.75 0.25 FALSE
15 The Cancer Genome Atlas Testicular Germ Cell Tumors FEZ2 0.18 0.21 lasso 6 0.21 5.3e-08 -6.6 -7.0 1.8e-12 0.92 0.01 0.99 TRUE