[Hub]/) : Traits : Peak expiratory flow (PEF) :

chr10:11,477,584-13,569,805

Best TWAS P=2.44e-14 · Best GWAS P=1.22e-17 conditioned to 0.0398

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Lung CAMK1D 0.28 0.24 enet 25 0.24 2.3e-18 -5.6 -5.4 5.4e-08 0.51 1.00 0.00 FALSE
2 GTEx Whole Blood CAMK1D 0.14 0.01 enet 26 0.04 2.5e-04 -5.6 -5.5 4.5e-08 0.63 0.22 0.70 FALSE
3 METSIM Adipose SEC61A2 0.07 0.02 bslmm 546 0.02 4.4e-04 -4.2 5.3 1.3e-07 -0.15 0.74 0.01 TRUE
4 NTR Blood CAMK1D 0.10 0.09 bslmm 900 0.08 4.4e-25 -5.6 -6.1 1.4e-09 0.59 1.00 0.00 FALSE
5 NTR Blood CDC123 0.06 0.04 bslmm 537 0.04 4.7e-14 -8.6 -7.6 2.4e-14 0.91 0.00 1.00 TRUE
6 YFS Blood CAMK1D 0.27 0.23 bslmm 875 0.26 7.7e-86 -5.6 -6.3 3.9e-10 0.63 1.00 0.00 FALSE
7 YFS Blood NUDT5 0.13 0.12 enet 40 0.13 1.1e-41 -5.6 -7.1 1.4e-12 0.71 1.00 0.00 FALSE
8 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma CDC123 0.26 0.07 lasso 4 0.07 1.4e-03 -5.6 6.5 7.9e-11 -0.65 0.11 0.12 FALSE
9 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NUDT5 0.13 -0.01 blup 55 0.01 1.1e-01 -5.1 -7.4 1.5e-13 0.53 0.02 0.14 FALSE
10 The Cancer Genome Atlas Soft Tissue Sarcoma CDC123 0.08 0.00 blup 64 0.03 4.0e-03 -1.6 -7.0 2.2e-12 0.64 0.01 0.15 FALSE
11 The Cancer Genome Atlas Soft Tissue Sarcoma NUDT5 0.08 0.07 enet 8 0.07 8.2e-05 -3.3 -6.9 3.9e-12 0.51 0.83 0.06 FALSE