Hub : Genes

GFM1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0630 0.0260 2.2e-04 0.048 0.039 0.045 0.041 0.049 1.4e-06 1.5e-05 3.1e-06 8.3e-06 1.1e-06
2 GTEx Adipose Subcutaneous 0.1710 0.0390 3.5e-12 0.227 NA 0.207 NA 0.218 1.9e-18 NA 7.8e-17 NA 1.1e-17
3 GTEx Adipose Visceral Omentum 0.1110 0.0400 4.0e-04 0.132 NA 0.095 NA 0.108 2.5e-07 NA 1.2e-05 NA 3.1e-06
4 GTEx Artery Aorta 0.2310 0.0580 1.7e-07 0.182 NA 0.161 NA 0.166 2.6e-10 NA 3.4e-09 NA 1.8e-09
5 GTEx Artery Coronary 0.1580 0.0570 7.3e-04 0.065 NA 0.112 NA 0.112 3.2e-03 NA 1.4e-04 NA 1.3e-04
6 GTEx Artery Tibial 0.1320 0.0493 8.7e-05 0.089 NA 0.089 NA 0.077 1.9e-07 NA 1.7e-07 NA 1.1e-06
7 GTEx Brain Cerebellar Hemisphere 0.4230 0.0830 1.8e-07 0.378 NA 0.346 NA 0.417 1.1e-10 NA 9.9e-10 NA 6.8e-12
8 GTEx Brain Cerebellum 0.4660 0.0810 4.6e-09 0.299 NA 0.389 NA 0.424 1.7e-09 NA 1.5e-12 NA 7.5e-14
9 GTEx Breast Mammary Tissue 0.2140 0.0610 1.1e-05 0.085 NA 0.090 NA 0.081 3.7e-05 NA 2.2e-05 NA 5.6e-05
10 GTEx Breast Mammary Tissue (Male) 0.2575 0.1089 8.0e-03 0.015 NA 0.068 NA 0.084 1.4e-01 NA 1.2e-02 NA 5.4e-03
11 GTEx Breast Mammary Tissue (Female) 0.0590 0.0654 2.3e-01 0.001 NA 0.011 NA 0.007 2.9e-01 NA 1.4e-01 NA 1.9e-01
12 GTEx Cells Transformed fibroblasts 0.2430 0.0630 1.2e-09 0.182 NA 0.144 NA 0.173 1.2e-13 NA 6.7e-11 NA 5.8e-13
13 GTEx Colon Transverse 0.2640 0.0650 1.1e-08 0.289 NA 0.249 NA 0.287 3.4e-14 NA 3.6e-12 NA 4.2e-14
14 GTEx Esophagus Mucosa 0.3090 0.0550 1.1e-16 0.295 NA 0.299 NA 0.313 5.2e-20 NA 2.5e-20 NA 2.3e-21
15 GTEx Esophagus Muscularis 0.2360 0.0660 3.8e-07 0.167 NA 0.178 NA 0.158 2.4e-10 NA 5.6e-11 NA 7.2e-10
16 GTEx Heart Atrial Appendage 0.1630 0.0590 4.7e-04 0.123 NA 0.045 NA 0.104 3.6e-06 NA 4.3e-03 NA 2.1e-05
17 GTEx Heart Left Ventricle 0.2677 0.0696 1.2e-07 0.183 NA 0.130 NA 0.174 5.0e-10 NA 2.2e-07 NA 1.4e-09
18 GTEx Lung 0.1427 0.0367 1.2e-08 0.150 NA 0.136 NA 0.141 1.3e-11 NA 1.5e-10 NA 6.7e-11
19 GTEx Muscle Skeletal 0.2047 0.0433 7.3e-14 0.143 NA 0.171 NA 0.176 6.7e-14 NA 1.5e-16 NA 5.6e-17
20 GTEx Nerve Tibial 0.1992 0.0446 2.8e-13 0.253 NA 0.251 NA 0.264 5.6e-18 NA 7.9e-18 NA 7.9e-19
21 GTEx Ovary 0.2370 0.0780 1.4e-04 0.154 NA 0.129 NA 0.166 1.3e-04 NA 4.7e-04 NA 7.0e-05
22 GTEx Pancreas 0.2320 0.0640 3.3e-06 0.160 NA 0.117 NA 0.124 2.8e-07 NA 1.3e-05 NA 6.7e-06
23 GTEx Skin Not Sun Exposed Suprapubic 0.1670 0.0520 7.0e-06 0.135 NA 0.163 NA 0.165 7.7e-08 NA 3.0e-09 NA 2.2e-09
24 GTEx Skin Sun Exposed Lower leg 0.2630 0.0510 3.9e-16 0.214 NA 0.240 NA 0.246 1.4e-17 NA 9.4e-20 NA 2.5e-20
25 GTEx Spleen 0.1710 0.0670 2.1e-03 0.120 NA 0.034 NA 0.131 5.5e-04 NA 4.7e-02 NA 3.0e-04
26 GTEx Testis 0.1630 0.0540 2.2e-04 0.114 NA 0.090 NA 0.110 9.6e-06 NA 8.0e-05 NA 1.3e-05
27 GTEx Thyroid 0.1820 0.0430 2.1e-10 0.185 NA 0.187 NA 0.192 4.1e-14 NA 2.7e-14 NA 1.3e-14
28 GTEx Uterus 0.2710 0.1040 1.3e-03 0.256 NA 0.098 NA 0.218 5.5e-06 NA 5.1e-03 NA 3.1e-05
29 GTEx Vagina 0.4670 0.1050 1.9e-06 0.240 NA 0.218 NA 0.207 3.2e-06 NA 9.9e-06 NA 1.7e-05
30 METSIM Adipose 0.1550 0.0333 0.0e+00 0.204 0.170 0.192 0.194 0.198 7.1e-30 1.1e-24 5.7e-28 2.7e-28 7.1e-29
31 YFS Blood 0.1121 0.0224 0.0e+00 0.148 0.143 0.155 0.150 0.152 6.8e-46 1.5e-44 2.8e-48 1.4e-46 2.4e-47
32 TCGA Bladder Urothelial Carcinoma 0.1590 0.0560 2.0e-11 0.143 0.126 0.131 NA 0.133 4.1e-12 9.1e-11 3.5e-11 NA 2.3e-11
33 TCGA Breast Invasive Carcinoma 0.0602 0.0292 6.3e-11 0.056 0.054 0.049 NA 0.052 1.5e-11 3.2e-11 2.3e-10 NA 6.0e-11
34 TCGA Cervical Squamous Cell Carcinoma 0.1260 0.0640 1.5e-05 0.075 0.084 0.077 NA 0.096 1.5e-04 6.4e-05 1.3e-04 NA 1.9e-05
35 TCGA Head and Neck Squamous Cell Carcinoma 0.0858 0.0395 2.1e-07 0.048 0.050 0.033 NA 0.047 3.6e-06 2.4e-06 1.2e-04 NA 4.9e-06
36 TCGA Kidney Renal Clear Cell Carcinoma 0.0713 0.0333 4.3e-07 0.073 0.052 0.035 NA 0.069 1.4e-08 1.6e-06 7.9e-05 NA 3.2e-08
37 TCGA Kidney Renal Papillary Cell Carcinoma 0.0850 0.0530 8.6e-03 -0.003 0.036 0.014 NA -0.004 5.9e-01 3.8e-03 4.9e-02 NA 6.2e-01
38 TCGA Brain Lower Grade Glioma 0.1006 0.0464 6.4e-10 0.096 0.070 0.071 NA 0.074 5.0e-11 2.4e-08 1.9e-08 NA 8.8e-09
39 TCGA Liver Hepatocellular Carcinoma 0.1790 0.0780 1.7e-04 0.010 0.076 0.052 NA 0.046 1.1e-01 1.9e-04 1.8e-03 NA 3.1e-03
40 TCGA Lung Adenocarcinoma 0.0494 0.0231 3.2e-07 0.027 0.047 0.033 NA 0.046 3.4e-04 2.9e-06 8.6e-05 NA 4.2e-06
41 TCGA Lung Squamous Cell Carcinoma 0.0526 0.0267 8.8e-07 0.035 0.058 0.052 NA 0.052 6.5e-05 3.2e-07 1.4e-06 NA 1.3e-06
42 TCGA Ovarian Serous Cystadenocarcinoma 0.0580 0.0380 8.4e-03 0.005 0.037 0.032 NA 0.009 1.3e-01 1.6e-03 3.0e-03 NA 7.6e-02
43 TCGA Pancreatic Adenocarcinoma 0.1080 0.0560 3.1e-04 0.106 0.080 0.059 NA 0.088 3.3e-05 3.0e-04 1.8e-03 NA 1.5e-04
44 TCGA Pheochromocytoma and Paraganglioma 0.1030 0.0580 3.4e-03 0.035 0.051 0.009 NA 0.035 1.5e-02 4.2e-03 1.3e-01 NA 1.5e-02
45 TCGA Prostate Adenocarcinoma 0.1140 0.0395 2.8e-14 0.128 0.150 0.147 NA 0.141 2.6e-13 1.9e-15 4.1e-15 NA 1.4e-14
46 TCGA Skin Cutaneous Melanoma 0.1430 0.0900 9.5e-03 0.043 0.075 0.037 NA 0.031 2.6e-02 4.8e-03 3.7e-02 NA 5.1e-02
47 TCGA Stomach Adenocarcinoma 0.0550 0.0300 2.4e-04 0.066 0.036 0.032 NA 0.035 1.7e-05 1.2e-03 2.1e-03 NA 1.4e-03
48 TCGA Testicular Germ Cell Tumors 0.2850 0.1200 2.5e-05 0.160 0.102 0.119 NA 0.137 2.7e-06 1.9e-04 5.6e-05 NA 1.5e-05
49 TCGA Thyroid Carcinoma 0.0850 0.0370 3.0e-09 0.105 0.103 0.103 NA 0.102 2.3e-10 3.5e-10 2.9e-10 NA 3.7e-10

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49
Bipolar Disorder (2018) 0.6 1.0 4.6 2.1 0.7 0.8 1.1 0.7 0.2 0.7 1.2 -0.5 -0.1 0.0 0.8 0.7 1.0 0.7 0.9 -0.1 0.6 1.1 1.1 1.1 0.7 1.3 1.2 0.8 -0.6 1.1 0.8 1.0 0.9 -0.3 1.3 1.0 1.2 1.8 1.0 -0.2 0.9 0.0 1.7 1.8 1.0 1.0 -0.3 1.2 0.0 0.6 1.8 0.5
Bipolar Disorder or Schizophrenia 0.3 0.7 1.9 1.2 0.8 0.8 1.0 0.5 0.2 1.0 0.8 0.1 -0.0 0.0 0.8 0.8 0.9 0.5 0.8 0.3 0.7 0.8 1.0 0.7 0.6 1.0 1.0 0.8 0.0 1.0 0.8 0.6 0.9 -0.3 1.1 0.9 1.1 1.4 1.0 0.7 0.8 0.4 1.3 1.3 1.1 1.0 0.2 1.0 0.5 0.7 1.3 0.5
Depressed Affect (Nagel 2018) 2.0 4.2 9.1 -2.2 -2.3 -2.4 -2.3 -2.6 -2.4 -1.5 -2.2 -1.8 -0.6 0.0 -2.3 -2.4 -2.2 -2.5 -2.3 -1.8 -2.4 -1.2 -2.7 -2.4 -2.3 -2.2 -2.3 -2.3 -0.9 -2.3 -2.3 -1.7 -2.3 2.5 -1.5 -1.6 -2.4 -0.9 -2.2 -0.7 -2.4 0.3 -1.9 -2.2 -0.5 -2.6 -1.6 -1.0 -2.5 -3.0 -0.7 -2.4
Depression (Nagel 2018) 1.2 1.7 4.5 -1.0 -1.5 -1.6 -1.5 -1.3 -1.4 -1.1 -1.5 -1.4 0.2 0.0 -1.5 -1.6 -1.5 -2.1 -1.6 -0.8 -1.6 -0.5 -2.0 -1.7 -1.5 -1.4 -1.4 -1.6 -0.2 -1.3 -1.5 -0.6 -1.5 1.9 -0.4 -0.9 -1.5 -0.3 -1.4 0.6 -1.3 1.2 -1.0 -1.4 0.2 -1.8 -0.8 -0.4 -1.5 -2.0 -0.2 -1.4
Intelligence (Savage-Jansen 2018) 0.6 1.7 7.7 -1.7 -1.1 -1.1 -1.1 -1.2 -0.6 -1.0 -1.3 -1.1 -2.2 0.0 -1.2 -1.1 -1.3 -0.7 -1.2 -1.6 -1.1 -1.4 -1.1 -1.3 -1.6 -1.4 -1.5 -1.1 -0.7 -1.5 -1.1 -2.8 -1.2 0.6 -2.0 -1.2 -1.7 -1.6 -1.1 -1.0 -1.0 -0.9 -1.5 -1.4 -1.6 -1.1 -0.8 -1.7 -1.0 -0.9 -0.7 -0.9
Neuroticism (Nagel 2018) 1.0 2.3 6.1 -1.7 -1.8 -1.6 -1.7 -2.0 -1.7 -0.7 -1.6 -0.6 0.5 0.0 -1.8 -1.6 -1.6 -2.4 -1.8 -1.1 -1.6 -0.4 -2.4 -1.9 -1.6 -1.7 -1.5 -1.8 -0.1 -1.6 -1.8 -1.7 -1.8 1.5 -0.6 -0.5 -1.7 -0.2 -1.6 0.6 -1.9 1.3 -1.3 -1.7 0.5 -2.1 -0.4 -0.2 -1.6 -2.5 -0.1 -1.6
Schizophrenia (2018) 0.1 0.2 1.1 -0.2 0.4 0.4 0.5 0.1 0.1 0.7 0.1 0.5 0.0 0.0 0.4 0.4 0.3 0.1 0.3 0.4 0.4 0.2 0.3 0.0 0.2 0.2 0.3 0.4 0.5 0.4 0.4 -0.0 0.4 -0.2 0.4 0.4 0.4 0.3 0.4 1.1 0.4 0.5 0.3 0.2 0.6 0.5 0.5 0.3 0.6 0.4 0.3 0.3
Schizophrenia vs Biploar Disorder 0.3 0.5 3.2 -1.8 -0.4 -0.4 -0.4 -0.5 -0.5 0.0 -0.8 -0.4 -0.0 0.0 -0.4 -0.4 -0.6 -0.7 -0.5 0.1 -0.6 -0.4 -0.8 -1.2 -0.6 -0.8 -0.7 -0.4 0.9 -0.7 -0.5 -0.1 -0.6 -0.1 -0.7 -0.7 -0.8 -1.0 -0.7 0.2 -0.5 0.2 -1.1 -1.1 -0.4 -0.5 0.5 -0.6 0.3 -0.3 -1.6 -0.3
Worry (Nagel 2018) 0.5 1.1 3.3 -1.6 -1.0 -1.0 -1.1 -1.1 -0.9 -0.2 -1.1 0.7 1.7 0.0 -1.0 -1.1 -1.0 -1.7 -1.1 -0.1 -1.1 0.0 -1.6 -1.1 -0.6 -1.0 -1.0 -1.1 1.1 -1.0 -1.0 -0.7 -1.1 0.9 -0.2 -0.1 -1.2 -0.0 -1.0 1.0 -1.2 1.7 -1.1 -1.4 0.8 -1.4 0.3 0.2 -0.6 -1.8 -0.6 -1.0
Alzheimer’s Disease (in mother) 0.3 0.3 1.9 -0.0 0.5 0.5 0.6 -0.0 0.2 0.6 0.3 1.4 0.9 0.0 0.5 0.5 0.6 1.0 0.5 0.5 0.5 0.8 0.4 0.4 0.7 0.4 0.7 0.5 1.0 0.5 0.5 -0.2 0.4 -0.6 0.5 0.2 0.7 0.3 0.1 -0.2 0.2 0.1 0.1 0.3 0.5 0.5 0.6 0.7 0.8 0.4 -1.1 0.3
Alzheimer’s Disease (in father) 0.1 0.1 0.4 -0.2 -0.2 -0.2 -0.2 -0.1 0.0 0.2 0.1 0.4 0.1 0.0 -0.2 -0.3 -0.1 -0.2 -0.2 -0.1 -0.3 0.3 -0.5 -0.2 -0.3 -0.0 -0.1 -0.3 0.3 -0.2 -0.3 -0.5 -0.3 -0.0 0.1 0.1 -0.3 0.4 -0.3 0.0 -0.2 0.5 -0.2 -0.2 0.5 -0.4 -0.1 0.3 -0.1 -0.6 -0.3 -0.1
Alzheimer’s Disease (including proxy) 0.2 0.3 2.3 -0.2 0.3 0.2 0.4 -0.1 0.3 0.6 0.3 1.5 1.2 0.0 0.3 0.2 0.4 0.5 0.3 0.5 0.3 1.1 -0.0 0.1 0.4 0.3 0.5 0.2 1.3 0.4 0.3 -0.2 0.1 -0.5 0.7 0.4 0.5 0.4 -0.2 -0.0 -0.1 0.5 -0.2 0.0 0.8 0.1 0.8 0.9 0.8 -0.1 -1.3 0.2
Crohns Disease (2017) 0.2 0.4 4.0 -0.3 0.0 -0.1 -0.1 0.4 0.9 0.7 0.3 1.3 2.0 0.0 -0.1 -0.1 0.1 -0.1 0.1 1.0 -0.1 1.2 -0.3 -0.5 0.2 0.3 0.2 -0.1 1.6 0.2 -0.1 -0.3 -0.2 -0.1 0.8 0.2 0.2 0.0 -0.4 0.4 -0.1 0.9 -0.4 -0.3 0.8 -0.1 1.1 0.8 0.9 -0.2 -1.7 0.4
Irritable Bowel Disease (IBD) 0.4 0.9 6.7 -0.9 -1.1 -1.2 -1.2 -0.4 0.2 -0.2 -0.7 0.5 1.4 0.0 -1.2 -1.1 -0.9 -0.7 -0.9 -0.0 -1.1 0.6 -1.3 -1.2 -0.8 -0.7 -0.7 -1.1 0.9 -0.8 -1.1 -1.2 -1.3 0.7 -0.0 -0.9 -0.7 -0.8 -1.6 -0.7 -1.1 0.2 -1.3 -1.1 -0.1 -1.1 0.2 -0.0 0.0 -1.1 -2.6 -0.6
Ulcerative Colitis (UC) 1.3 2.4 4.3 -1.0 -1.9 -1.9 -2.0 -1.3 -0.8 -1.5 -1.6 -1.1 -0.3 0.0 -1.9 -1.9 -1.8 -1.2 -1.8 -1.4 -1.8 -0.8 -1.8 -1.6 -1.7 -1.7 -1.6 -1.9 -0.7 -1.7 -1.9 -1.7 -2.0 1.4 -1.1 -1.8 -1.6 -1.4 -2.1 -1.5 -1.8 -0.9 -1.6 -1.5 -1.2 -1.8 -1.2 -1.2 -1.3 -1.7 -1.8 -1.7
Major Depression (MDD) 0.3 0.3 2.8 -0.5 -0.5 -0.4 -0.4 -1.7 -0.2 -0.8 -0.6 -0.8 -0.5 0.0 -0.5 -0.5 -0.5 -1.1 -0.5 -0.8 -0.5 -0.4 -0.6 -0.4 -0.7 -0.5 -0.5 -0.5 -0.4 -0.5 -0.5 -0.6 -0.4 0.6 -0.2 -0.1 -0.5 -0.0 -0.2 0.4 -0.5 0.2 -0.3 -0.5 0.1 -0.7 -0.2 -0.2 -0.7 -0.7 0.6 -0.6
Reaction Time 0.4 0.7 2.3 1.3 0.5 0.5 0.8 0.8 1.2 0.8 1.0 1.5 1.3 0.0 0.5 0.5 0.8 1.2 0.7 0.8 0.5 1.2 0.6 0.5 0.8 0.9 0.9 0.5 0.4 0.8 0.5 0.7 0.5 -0.7 1.1 0.7 0.8 1.2 0.6 0.7 0.7 1.3 1.0 1.0 1.0 0.5 0.5 1.1 0.2 0.3 0.9 0.7
Verbal and Numeric Reasoning (VNR) 0.1 0.3 1.8 -1.0 -0.5 -0.5 -0.4 -0.4 -0.0 0.2 -0.3 -0.3 -0.9 0.0 -0.5 -0.5 -0.4 -0.1 -0.4 -0.8 -0.5 -0.1 -0.7 -0.6 -0.8 -0.4 -0.6 -0.5 0.2 -0.6 -0.5 -1.3 -0.5 0.2 -0.7 -0.3 -0.8 -0.2 -0.5 -0.3 -0.5 0.2 -0.6 -0.6 -0.1 -0.5 -0.2 -0.3 -0.4 -0.7 -0.3 -0.3
Breast Cancer 0.9 2.2 7.1 -0.6 -2.0 -1.9 -1.6 -0.6 -1.1 -1.0 -1.0 0.7 0.7 0.0 -1.9 -2.0 -1.4 -0.9 -1.6 -1.1 -2.0 0.3 -1.7 -1.5 -1.5 -1.1 -1.1 -2.0 -0.8 -1.2 -1.9 -0.4 -2.0 1.9 -0.1 -1.8 -1.0 -0.6 -2.3 -2.6 -1.8 -1.1 -1.2 -0.8 -0.8 -1.9 -1.8 -0.3 -1.4 -2.0 -2.7 -1.9
Ovarian Cancer 0.9 1.1 3.1 -0.7 -1.2 -1.2 -0.9 -0.7 -0.9 -0.6 -0.5 1.3 0.3 0.0 -1.2 -1.2 -1.0 -0.5 -1.1 -1.0 -1.3 -0.4 -1.7 -1.1 -0.7 -0.7 -0.9 -1.3 -0.6 -1.1 -1.2 -0.8 -1.3 1.5 -0.7 -1.1 -0.9 -0.5 -1.4 -1.6 -1.3 -0.7 -1.3 -1.2 -0.1 -1.6 -1.0 -0.2 -1.3 -1.8 -1.7 -0.9
Prostate Cancer 2.0 2.7 4.4 -1.6 -1.7 -1.6 -1.9 -1.4 -1.4 -1.7 -1.9 -1.5 -1.7 0.0 -1.6 -1.6 -1.8 -1.2 -1.8 -1.4 -1.7 -2.1 -1.6 -1.1 -1.6 -1.9 -1.9 -1.6 -1.6 -1.9 -1.7 -1.4 -1.7 1.5 -2.1 -1.9 -1.9 -2.1 -1.6 -1.4 -1.6 -1.7 -1.8 -1.8 -2.0 -1.6 -1.6 -2.1 -1.6 -1.3 -1.0 -1.6
Age at First Birth 0.9 1.3 3.0 1.0 1.4 1.2 1.5 1.4 1.1 1.0 0.9 1.5 0.7 0.0 1.5 1.3 1.3 0.8 1.3 1.1 1.2 0.7 1.4 1.5 1.7 1.1 1.2 1.5 0.8 1.3 1.5 1.2 1.4 -1.2 0.7 0.7 1.5 -0.0 0.9 -0.6 0.8 -0.9 0.6 0.8 -0.0 1.5 0.8 0.7 1.5 1.5 -0.5 1.0
Bipolar Disorder (2011) 0.1 0.1 1.0 0.9 -0.3 -0.1 -0.3 0.1 -0.3 -0.5 -0.0 -0.4 -0.4 0.0 -0.4 -0.2 -0.1 -0.1 -0.1 -0.5 -0.1 -0.1 0.1 0.3 -0.3 -0.1 0.1 -0.3 -0.9 0.0 -0.3 0.0 -0.2 0.4 0.2 -0.3 0.4 0.1 -0.1 -0.7 0.0 -1.0 0.3 0.4 -0.3 -0.1 -0.7 -0.1 -0.1 0.1 -0.2 -0.3
Body Mass Index (BMI) (2010) 0.4 0.5 5.3 0.2 0.2 0.2 0.2 0.5 0.7 0.6 0.5 2.3 1.7 0.0 0.2 0.2 0.3 0.6 0.3 0.5 0.2 0.9 -0.1 0.2 0.6 0.5 0.6 0.2 1.0 0.5 0.2 1.0 0.1 -0.1 1.1 -0.1 1.0 0.2 -0.4 -0.6 -0.1 -0.5 -0.3 0.0 0.8 0.2 0.5 0.9 1.0 0.1 -2.3 0.3
Coronary Artery Disease (CAD) 3.8 4.5 7.4 1.6 2.0 2.3 2.2 2.1 2.2 2.6 2.5 1.7 1.8 0.0 2.1 2.2 2.3 2.0 2.2 2.0 2.1 2.3 2.2 2.0 1.9 2.3 2.3 2.0 1.6 2.4 2.0 2.7 2.1 -2.1 2.7 2.2 2.5 2.0 2.0 1.9 2.3 1.7 2.2 2.2 1.9 2.1 2.1 2.3 2.3 2.1 1.0 2.4
Crohns Disease (2012) 0.9 1.4 4.9 0.6 1.1 1.0 0.9 1.7 1.4 1.3 1.1 1.8 2.2 0.0 1.0 1.0 1.0 0.7 1.1 1.8 0.9 1.2 1.1 0.9 1.4 1.1 1.0 1.1 1.7 1.2 1.1 0.8 1.0 -1.4 1.4 1.4 1.1 0.6 0.9 1.7 1.0 1.1 0.7 0.7 1.0 1.1 1.8 1.0 1.7 1.1 0.1 1.4
Mean Putamen Volume 0.7 0.8 4.2 0.6 -0.9 -0.8 -0.5 -0.5 -0.5 -0.9 -0.3 -1.1 -1.6 0.0 -0.7 -0.8 -0.4 -0.3 -0.5 -1.4 -0.9 -0.2 -0.6 0.0 -1.1 -0.3 -0.4 -0.8 -2.0 -0.4 -0.7 -0.2 -0.6 1.6 -0.2 -0.8 -0.3 0.4 -0.5 -2.0 -0.6 -1.3 0.3 0.4 -0.3 -0.6 -2.1 -0.1 -1.6 -1.0 0.4 -1.1
Fasting Glucose 0.4 0.5 2.0 -0.2 1.0 0.3 0.9 1.0 1.1 0.3 0.0 0.2 0.8 0.0 1.2 0.5 0.6 0.6 0.5 1.4 0.4 0.0 0.7 0.5 1.0 0.5 0.1 1.1 1.4 0.7 1.1 0.1 0.9 -0.5 0.2 0.3 0.1 -0.4 0.5 0.8 0.4 0.4 -0.4 -0.4 0.0 0.9 1.0 -0.0 0.9 0.5 -0.6 0.5
HbA1C 3.3 3.7 5.8 -2.2 -1.8 -2.3 -1.7 -2.0 -1.5 -2.4 -2.2 -2.1 -1.6 0.0 -1.7 -2.2 -2.0 -2.0 -2.0 -1.7 -2.1 -2.2 -1.7 -2.0 -1.8 -2.0 -2.4 -1.7 -1.1 -2.1 -1.8 -1.6 -1.8 1.9 -2.1 -1.8 -2.4 -2.1 -1.8 -1.7 -2.1 -1.8 -2.2 -2.2 -2.1 -1.7 -1.5 -2.1 -1.7 -1.9 -1.4 -2.0
HDL Cholesterol 0.2 0.4 2.2 -0.0 -0.5 -0.8 -0.4 -0.7 0.1 -1.1 -0.7 -1.5 -0.7 0.0 -0.5 -0.7 -0.5 -0.9 -0.5 -0.5 -0.5 -0.7 -0.3 -0.9 -0.6 -0.6 -0.6 -0.5 -0.8 -0.5 -0.5 0.2 -0.4 0.4 -0.5 -0.4 -0.8 -0.4 -0.2 0.0 -0.3 0.1 -0.1 -0.3 -0.6 -0.4 -0.5 -0.7 -1.0 -0.4 1.0 -0.6
LDL Cholesterol 1.5 2.3 3.9 -2.0 -1.6 -1.3 -1.9 -1.6 -1.5 -1.3 -1.6 -0.6 -0.7 0.0 -1.6 -1.5 -1.8 -1.1 -1.8 -1.5 -1.8 -1.8 -1.7 -1.4 -1.5 -1.8 -1.9 -1.6 -1.0 -1.8 -1.7 -1.0 -1.7 1.4 -1.7 -1.6 -1.7 -1.9 -1.6 -0.9 -1.7 -1.0 -1.9 -2.0 -1.6 -1.7 -0.9 -1.8 -1.4 -1.5 -1.1 -1.3
Lupus 1.0 1.5 4.0 -0.9 -1.4 -1.4 -1.4 -1.3 -0.4 -1.2 -1.3 -0.2 -0.3 0.0 -1.4 -1.4 -1.5 -2.0 -1.4 -1.3 -1.4 -1.2 -1.1 -1.0 -1.1 -1.3 -1.4 -1.4 -1.0 -1.3 -1.4 -0.5 -1.4 1.3 -0.9 -1.2 -1.1 -1.4 -1.4 -1.0 -1.3 -1.4 -1.3 -1.2 -1.4 -1.3 -0.9 -1.4 -1.0 -1.1 -1.0 -1.3
Neuroticism (2016) 0.7 1.1 3.8 -0.9 -1.1 -1.2 -1.0 -1.8 -0.6 -1.1 -1.1 -1.9 -0.6 0.0 -1.2 -1.2 -0.8 -1.3 -0.9 -1.3 -1.1 -0.2 -1.2 -1.5 -1.2 -1.0 -0.9 -1.2 -0.9 -0.9 -1.1 -1.3 -1.1 1.4 -0.3 -0.6 -0.9 0.1 -0.8 -0.6 -0.9 0.2 -0.3 -0.4 -0.0 -1.3 -1.2 -0.2 -1.4 -1.5 0.1 -1.4
Primary Biliary Cirrhosis 0.7 0.9 2.8 -0.9 -1.2 -1.2 -1.1 -1.4 -0.3 -0.6 -0.7 -0.4 0.1 0.0 -1.2 -1.3 -1.1 -0.2 -1.1 -1.3 -1.3 -0.3 -1.4 -1.3 -1.1 -0.7 -0.9 -1.2 -0.4 -1.0 -1.2 -0.4 -1.2 1.0 -0.2 -0.8 -0.7 -0.2 -1.3 -0.8 -1.4 -0.4 -1.1 -1.0 0.1 -1.3 -0.8 -0.2 -1.0 -1.7 -1.1 -1.0
Rheumatoid Arthritis 0.1 0.2 0.9 0.4 0.5 0.5 0.5 -0.0 0.9 0.1 0.4 -0.8 -0.5 0.0 0.5 0.5 0.5 0.4 0.5 0.1 0.5 0.0 0.4 0.3 0.5 0.4 0.4 0.5 -0.1 0.4 0.5 0.7 0.5 -0.4 -0.0 0.2 0.3 0.2 0.6 0.2 0.6 0.1 0.5 0.5 0.1 0.5 -0.0 0.1 0.1 0.6 0.7 0.5
Schizophrenia (2014) 0.1 0.2 1.7 0.1 0.5 0.5 0.5 0.0 0.3 0.7 0.2 -0.2 0.3 0.0 0.4 0.5 0.3 0.5 0.4 0.4 0.4 0.4 0.4 0.1 0.3 0.3 0.4 0.5 0.6 0.5 0.5 0.3 0.5 -0.3 0.7 0.6 0.5 0.5 0.5 1.3 0.5 0.6 0.5 0.5 0.7 0.6 0.6 0.4 0.8 0.6 0.5 0.3
Triglycerides 2.8 4.5 6.4 -2.3 -2.4 -2.2 -2.5 -2.3 -2.1 -2.0 -2.1 -0.6 -0.7 0.0 -2.4 -2.3 -2.4 -2.4 -2.4 -2.1 -2.5 -1.7 -2.4 -2.1 -2.0 -2.3 -2.3 -2.4 -1.3 -2.3 -2.4 -1.7 -2.4 2.2 -1.8 -2.3 -2.0 -2.2 -2.5 -2.2 -2.5 -1.8 -2.4 -2.3 -1.9 -2.4 -1.7 -1.9 -1.8 -2.2 -2.3 -2.0
Type 2 Diabetes (T2D) (2012) 1.9 2.2 7.7 0.1 1.3 1.2 1.4 1.2 2.4 2.0 1.3 1.9 2.4 0.0 1.3 1.2 1.2 1.4 1.3 1.8 1.2 2.0 0.5 0.8 1.4 1.3 1.3 1.2 2.8 1.3 1.2 0.6 1.1 -1.3 1.8 1.5 1.3 1.2 0.8 2.1 1.0 2.4 0.5 0.4 2.2 1.0 2.4 1.9 1.8 0.7 -0.6 1.6
Ulcerative Colitis 0.2 0.3 2.0 0.3 -0.7 -0.6 -0.6 0.5 -0.3 -0.4 -0.2 0.3 0.3 0.0 -0.6 -0.6 -0.4 -0.0 -0.5 -0.2 -0.6 0.3 -0.4 0.1 -0.2 -0.2 -0.2 -0.6 -0.5 -0.3 -0.6 0.3 -0.6 0.5 0.0 -1.0 -0.0 -0.4 -0.9 -1.4 -0.4 -1.0 -0.2 0.0 -0.6 -0.4 -0.9 -0.2 -0.3 -0.3 -1.3 -0.6
Blood Eosinophil Count 0.2 1.8 6.2 -1.8 -1.5 -1.5 -1.3 -1.8 -1.2 -0.6 -1.2 -0.9 0.2 0.0 -1.5 -1.5 -1.3 -1.7 -1.4 -1.0 -1.6 -0.0 -2.0 -2.5 -1.8 -1.3 -1.3 -1.6 0.6 -1.4 -1.5 -0.7 -1.6 1.4 -0.6 -0.9 -1.5 -0.6 -1.7 -0.3 -1.6 0.6 -1.6 -1.6 0.1 -1.6 -0.3 -0.2 -0.9 -2.0 -1.8 -1.3
Blood Platelet Count 0.1 1.0 3.1 1.5 0.6 0.6 1.0 0.3 -0.1 1.1 1.1 -0.6 1.0 0.0 0.6 0.6 1.0 1.0 0.9 0.6 0.6 1.8 1.0 0.3 0.6 1.1 1.1 0.6 0.4 1.1 0.6 1.5 0.7 -0.6 1.7 1.0 0.9 1.8 0.9 1.0 1.1 1.8 1.7 1.6 1.2 0.7 0.3 1.5 0.1 0.5 1.7 0.6
Blood Red Count 0.2 1.6 3.7 0.4 1.6 1.6 1.4 0.6 0.2 1.2 0.7 1.1 0.5 0.0 1.7 1.6 1.3 1.5 1.4 1.1 1.6 0.4 1.6 1.7 1.8 0.9 1.3 1.6 1.1 1.3 1.6 1.7 1.5 -1.7 0.6 1.0 1.3 0.0 1.4 0.9 1.2 -0.0 0.7 0.7 0.3 1.6 1.7 0.5 1.8 1.9 0.2 1.3
Blood White Count 0.0 0.2 2.8 0.3 -0.1 -0.1 0.1 -0.7 -0.4 -0.1 -0.2 -0.7 -1.0 0.0 -0.1 -0.1 -0.1 -0.5 -0.0 -0.5 -0.1 -0.3 0.4 -0.3 -0.2 -0.1 -0.1 -0.1 -1.0 -0.1 -0.1 0.9 0.0 -0.2 -0.2 0.1 -0.2 0.2 0.4 -0.2 0.2 -0.1 0.5 0.4 -0.5 0.2 -0.5 -0.4 -0.7 0.1 1.7 -0.2
Heel T-Score 0.0 0.3 6.1 -0.6 -0.0 -0.1 -0.2 0.2 -0.7 0.9 -0.1 2.5 0.7 0.0 -0.0 -0.1 -0.2 -0.7 -0.1 0.4 -0.1 -0.2 -0.0 0.5 0.6 -0.1 -0.3 -0.1 0.2 -0.2 -0.1 0.1 -0.1 -0.2 -0.4 -0.2 -0.1 -1.1 -0.2 -0.8 -0.1 -0.6 -0.6 -0.5 -1.0 -0.2 0.2 -0.5 0.1 0.1 -0.8 0.2
BMI 0.2 1.4 5.4 0.9 1.1 1.1 1.2 1.6 0.5 1.2 1.0 2.1 1.9 0.0 1.1 1.0 1.1 1.2 1.1 1.3 1.0 1.6 0.8 0.2 1.3 0.9 1.4 1.0 1.9 1.2 1.1 1.7 0.9 -1.3 1.3 0.4 1.5 0.5 0.3 -0.3 0.6 -0.2 0.2 0.7 1.0 1.2 1.4 1.4 1.9 1.1 -2.3 0.9
Height 0.2 4.1 45.2 0.2 2.1 2.1 1.7 -0.2 -0.4 0.3 0.2 0.0 -3.2 0.0 2.1 2.2 1.1 -1.2 1.5 0.6 2.2 -2.3 2.9 3.5 1.6 0.6 0.3 2.2 -1.5 1.0 2.1 1.1 2.4 -2.0 -1.4 2.4 0.2 -0.6 3.5 2.7 2.3 0.2 1.7 1.0 -1.8 2.1 1.4 -1.9 0.3 2.9 6.7 1.8
Waist Hip Ratio (WHR) 0.9 3.9 10.5 -1.3 -2.2 -2.2 -2.0 -2.1 -2.8 -2.1 -1.9 -1.7 -2.1 0.0 -2.2 -2.1 -2.1 -3.2 -2.1 -2.0 -2.1 -2.1 -1.7 -1.9 -2.3 -1.8 -2.3 -2.1 -2.6 -2.1 -2.1 -1.0 -2.0 2.3 -1.9 -1.7 -2.3 -1.3 -1.5 -0.9 -1.5 -0.6 -1.0 -1.4 -1.8 -2.2 -2.2 -2.0 -2.8 -1.9 1.0 -2.0
Systolic Blood Pressure 0.4 2.2 17.0 -0.9 0.7 0.5 0.7 0.4 1.9 2.1 0.7 1.4 3.6 0.0 0.6 0.5 0.7 0.8 0.6 1.7 0.5 2.4 -0.6 -0.8 0.8 0.6 0.8 0.5 4.1 0.7 0.5 0.6 0.3 -1.3 1.8 0.9 0.7 0.8 -0.3 2.1 -0.0 2.9 -0.6 -0.6 2.6 0.3 2.6 2.2 2.1 -0.3 -2.8 1.0
Smoking Status 1.4 3.2 11.5 -1.2 -2.0 -2.0 -1.6 -2.5 -1.9 -1.8 -1.5 -3.4 -1.7 0.0 -2.0 -2.0 -1.9 -2.6 -1.9 -2.1 -2.0 -1.3 -1.8 -2.6 -2.3 -1.6 -2.0 -2.0 -1.6 -1.9 -2.0 -0.6 -1.9 2.0 -1.3 -1.4 -2.2 -0.4 -1.5 0.2 -1.3 0.5 -0.8 -1.1 -0.8 -2.0 -1.9 -1.4 -2.4 -2.0 0.9 -1.9
Allergy or Eczema 0.1 0.3 1.2 -0.1 -0.6 -0.7 -0.9 -0.6 -0.7 -0.6 -0.8 -1.1 0.0 0.0 -0.6 -0.6 -0.8 -0.1 -0.7 -0.8 -0.6 -0.6 -0.6 -0.1 -0.4 -0.7 -0.6 -0.7 -0.3 -0.6 -0.7 -0.3 -0.6 0.7 -0.1 -0.5 -0.4 -0.4 -0.7 0.0 -0.8 -0.7 -0.7 -0.6 -0.3 -0.5 -0.3 -0.5 -0.2 -0.6 -0.6 -0.8
Cardiovascular Disease 0.4 1.4 12.7 -0.4 -0.2 -0.3 -0.1 0.0 1.3 1.6 0.6 1.5 3.6 0.0 -0.4 -0.4 0.2 0.1 0.0 1.2 -0.4 2.5 -0.8 -1.1 0.1 0.5 0.4 -0.4 2.8 0.3 -0.3 0.1 -0.5 -0.2 1.8 0.2 0.4 0.7 -1.0 0.6 -0.2 2.2 -0.5 -0.3 1.8 -0.5 1.5 1.8 1.1 -0.8 -2.9 0.4
Hypothyroidism (self reported) 0.5 1.1 6.0 -0.5 1.0 0.9 0.9 0.2 1.7 1.6 0.7 0.7 1.5 0.0 0.9 1.0 0.8 0.4 0.9 1.0 1.0 1.2 0.4 -0.1 0.8 0.7 0.8 1.0 2.5 0.8 1.0 0.0 0.8 -1.5 1.0 1.1 0.8 0.7 0.6 1.8 0.7 1.6 0.0 0.1 1.6 0.8 2.1 1.2 1.7 0.6 -0.9 1.1
Respiratory disease 0.2 0.4 1.7 0.1 -0.5 -0.5 -0.3 -0.1 -0.3 -0.1 0.0 -1.1 0.9 0.0 -0.5 -0.5 -0.2 -0.1 -0.3 -0.3 -0.5 0.9 -0.6 -1.0 -0.4 -0.1 -0.2 -0.5 1.1 -0.2 -0.5 -1.3 -0.5 0.5 0.7 0.1 -0.3 1.1 -0.6 0.6 -0.3 1.1 -0.2 0.1 1.2 -0.3 0.1 0.8 0.2 -0.8 -0.9 -0.5
Type 2 Diabetes (T2D) (2018) 0.4 0.7 4.8 0.4 -0.2 -0.2 0.1 0.0 1.0 1.1 0.5 1.8 2.2 0.0 -0.2 -0.2 0.3 0.2 0.1 0.7 -0.2 1.8 -0.6 -0.7 0.0 0.5 0.4 -0.2 1.2 0.3 -0.2 -0.9 -0.3 0.2 1.3 0.3 0.4 1.2 -0.5 0.2 -0.2 1.5 0.1 0.2 1.7 -0.5 0.3 1.6 0.3 -0.9 -1.3 0.0
Lung FEV1/FVC ratio 0.3 1.7 13.0 -1.1 -1.4 -1.4 -1.2 -1.3 -0.1 -0.7 -1.4 0.3 1.4 0.0 -1.4 -1.4 -1.2 -1.2 -1.2 -0.5 -1.4 0.1 -1.7 -1.7 -0.9 -1.4 -1.0 -1.4 0.7 -1.2 -1.4 -0.6 -1.6 0.7 -0.4 -1.5 -0.9 -1.6 -2.0 -1.4 -1.9 -0.6 -2.1 -1.9 -0.7 -1.5 -0.1 -0.4 -0.3 -1.5 -3.6 -1.3
Lung FVC 0.7 3.7 38.5 2.3 0.2 0.5 0.8 0.3 -1.1 -1.5 0.5 -4.0 -4.8 0.0 0.6 0.4 0.5 -0.1 0.5 -1.8 0.4 -1.6 1.7 1.7 -0.3 0.6 0.5 0.4 -5.1 0.5 0.5 1.5 0.9 1.0 -0.5 0.2 0.5 1.5 1.9 -1.2 1.3 -1.8 2.9 2.7 -1.1 0.9 -3.4 -0.9 -2.6 0.9 6.2 -0.4
Neuroticism 0.5 1.2 5.0 -0.8 -1.2 -1.2 -1.0 -1.6 -1.1 -0.4 -0.8 0.1 1.1 0.0 -1.2 -1.3 -0.9 -1.9 -1.1 -0.6 -1.2 0.3 -1.8 -1.6 -0.9 -0.8 -0.9 -1.2 0.1 -0.9 -1.2 -1.1 -1.1 1.4 0.2 -0.1 -1.1 0.8 -0.9 0.8 -1.0 2.0 -0.5 -0.8 1.3 -1.6 -0.5 0.6 -1.5 -2.2 0.5 -1.1
Chronotype (morning person) 0.2 0.5 3.8 -1.0 -0.5 -0.5 -0.5 -0.6 -1.7 -0.7 -0.5 -0.5 0.0 0.0 -0.6 -0.5 -0.5 -1.4 -0.5 -0.2 -0.5 -0.3 -0.5 -0.7 -0.6 -0.5 -0.6 -0.5 -0.2 -0.4 -0.5 -0.1 -0.3 0.2 0.0 0.6 -0.8 0.3 0.1 1.3 -0.2 1.5 0.1 -0.3 0.4 -0.5 0.2 -0.1 -0.8 -0.8 2.0 -0.1
Hair Pigment 0.1 3.8 6.8 -2.0 -2.1 -2.1 -2.2 -2.2 -2.6 -2.1 -2.2 -1.8 -1.5 0.0 -2.1 -2.1 -2.1 -2.0 -2.2 -1.8 -2.1 -1.8 -2.0 -2.1 -2.2 -2.2 -2.1 -2.1 -1.5 -2.1 -2.1 -1.1 -2.1 1.9 -1.8 -2.3 -2.2 -2.0 -2.0 -1.1 -1.7 -0.9 -1.8 -1.9 -1.9 -2.1 -1.8 -2.0 -2.0 -1.7 -1.1 -2.1
Tanning 0.0 0.4 1.9 1.1 -0.6 -0.5 -0.1 -0.4 -0.3 -0.9 -0.3 -0.9 -1.0 0.0 -0.6 -0.6 -0.4 0.5 -0.5 -1.2 -0.6 -0.5 -0.2 -0.4 -0.6 -0.4 -0.3 -0.6 -1.2 -0.5 -0.6 0.2 -0.6 0.5 -0.4 -0.7 -0.3 -0.1 -0.5 -1.4 -0.5 -1.3 -0.1 0.1 -0.7 -0.3 -1.1 -0.5 -0.8 -0.4 -0.2 -0.8
Hand grip strength (left) 0.8 2.1 10.9 2.5 1.3 1.4 1.5 1.2 -0.2 0.7 1.5 -0.3 -1.4 0.0 1.5 1.4 1.5 0.6 1.5 0.5 1.4 0.5 1.8 2.4 1.2 1.6 1.5 1.4 -1.6 1.5 1.4 1.4 1.6 -0.7 0.8 1.3 1.5 1.7 2.0 -0.2 1.7 -0.3 2.4 2.3 0.6 1.5 -0.6 0.9 -0.2 1.4 3.3 1.1
Number of treatments/medications taken 2.3 4.1 9.4 -2.1 -2.5 -2.5 -2.2 -2.2 -1.1 -1.7 -1.9 -2.0 -0.1 0.0 -2.5 -2.6 -2.1 -2.1 -2.3 -1.8 -2.5 -0.5 -2.6 -3.1 -2.5 -2.0 -2.0 -2.5 -0.4 -2.1 -2.5 -1.6 -2.5 2.4 -0.9 -2.1 -2.1 -1.1 -2.6 -1.1 -2.2 0.1 -1.9 -1.8 -0.8 -2.5 -1.6 -0.9 -1.9 -2.7 -2.2 -2.3
Average weekly spirits intake 0.1 0.1 2.6 -0.1 0.1 0.1 0.2 -0.1 0.2 -0.2 0.1 1.0 0.6 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.2 -0.1 -0.3 0.2 -0.0 0.2 0.1 0.7 0.0 0.1 0.3 -0.0 -0.2 -0.1 -0.4 0.1 -0.5 -0.3 -0.4 -0.1 -0.3 -0.5 -0.3 -0.1 0.0 0.2 0.1 0.5 0.2 -1.6 0.0
Sensitivity / hurt feelings 1.0 1.7 6.5 -2.3 -1.2 -1.4 -1.3 -1.9 -1.4 -0.6 -1.5 -0.0 0.1 0.0 -1.3 -1.3 -1.3 -2.5 -1.4 -1.0 -1.3 -0.7 -1.8 -1.7 -1.3 -1.5 -1.5 -1.3 0.5 -1.4 -1.3 -1.8 -1.4 1.0 -1.1 -0.8 -1.7 -1.1 -1.4 -0.1 -1.5 0.5 -1.7 -1.9 -0.4 -1.4 -0.0 -0.8 -0.8 -1.7 -1.2 -1.2
Frequency of depressed mood in last 2 weeks 1.2 1.7 5.1 -1.0 -1.5 -1.5 -1.6 -1.2 -1.5 -1.1 -1.3 -1.4 0.3 0.0 -1.5 -1.5 -1.4 -2.2 -1.5 -0.7 -1.5 -0.5 -2.0 -1.6 -1.5 -1.3 -1.4 -1.5 -0.2 -1.2 -1.5 -1.1 -1.4 2.0 -0.2 -0.9 -1.3 -0.2 -1.4 0.7 -1.3 1.0 -1.0 -1.3 0.4 -1.8 -0.7 -0.3 -1.2 -2.0 -0.6 -1.3
Hearing difficulty/problems: Yes 0.1 0.1 0.8 0.5 -0.1 -0.0 0.2 -0.4 0.1 -0.1 0.0 -0.9 0.4 0.0 -0.1 -0.1 -0.0 0.0 0.0 0.3 -0.0 0.1 -0.2 -0.4 -0.1 -0.0 -0.0 -0.1 0.0 -0.0 -0.1 0.1 -0.0 -0.2 0.2 0.4 -0.2 0.5 0.2 0.8 0.1 0.9 0.3 0.0 0.6 -0.2 0.1 0.3 -0.2 -0.4 0.8 -0.0
Relative age of first facial hair 0.1 0.1 2.1 0.3 -0.1 0.0 -0.2 -0.4 0.2 0.0 0.2 0.9 -0.4 0.0 -0.1 -0.0 0.2 0.2 0.1 -0.3 -0.1 0.3 -0.1 -0.1 -0.3 0.2 0.2 -0.1 -0.4 0.1 -0.0 -1.5 -0.0 0.5 0.3 -0.4 0.3 0.3 -0.0 -0.3 0.2 0.0 0.4 0.4 0.2 -0.1 -0.6 0.3 -0.4 -0.1 -0.0 -0.1
Other serious medical condition/disability diagnosed by doctor 0.1 0.1 1.9 -0.6 0.2 0.1 0.0 -0.6 -0.3 0.0 -0.5 -0.1 -0.5 0.0 0.2 0.2 -0.2 -0.4 -0.1 -0.0 0.2 -0.6 0.1 -0.3 -0.2 -0.4 -0.3 0.2 0.6 -0.2 0.1 -0.4 0.1 -0.1 -0.3 0.1 -0.2 -0.3 0.2 1.4 0.0 0.4 -0.3 -0.5 0.0 0.1 0.6 -0.5 0.6 0.3 0.1 -0.0
Ever used hormone-replacement therapy (HRT) 0.4 0.5 3.4 -1.8 -0.6 -0.7 -0.6 -0.6 -0.7 -0.6 -0.9 -0.2 -0.1 0.0 -0.6 -0.7 -0.8 -1.1 -0.8 -0.2 -0.6 -0.7 -0.5 -1.0 -0.7 -0.9 -1.0 -0.7 0.3 -0.9 -0.7 0.5 -0.6 0.5 -0.8 -0.4 -1.2 -0.6 -0.5 0.7 -0.5 0.7 -0.8 -0.9 -0.7 -0.8 0.1 -0.9 -0.5 -0.6 0.1 -0.7
Ever had hysterectomy (womb removed) 0.2 0.2 1.7 0.5 0.3 0.3 0.3 0.1 -0.0 0.3 0.3 0.5 -0.1 0.0 0.3 0.3 0.3 0.6 0.3 -0.0 0.3 0.1 0.7 0.6 0.5 0.3 0.4 0.3 -0.3 0.3 0.3 -0.5 0.3 -0.2 0.0 -0.0 0.5 -0.0 0.2 -1.0 0.1 -1.3 0.2 0.5 -0.5 0.5 -0.2 -0.0 0.5 0.6 -0.4 0.0
Systolic blood pressure, automated reading 2.0 5.8 18.2 0.2 2.6 2.5 2.5 1.7 2.6 3.0 2.1 2.4 3.5 0.0 2.5 2.4 2.4 2.2 2.5 3.1 2.4 2.9 1.7 1.2 2.6 2.1 2.4 2.4 4.3 2.3 2.4 2.0 2.2 -3.2 2.3 2.1 2.3 1.3 1.7 2.5 1.8 2.5 1.0 1.0 2.6 2.3 3.5 2.7 3.5 2.1 -1.3 2.5
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 2.6 -0.6 0.1 0.1 -0.0 -0.0 1.1 0.5 0.2 1.4 1.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.8 -0.4 -0.6 -0.0 0.1 0.1 0.0 1.2 0.1 0.0 -0.7 0.0 -0.3 0.6 0.4 -0.0 0.5 0.0 1.1 0.2 1.6 0.0 -0.1 1.1 -0.0 0.9 0.7 0.3 -0.3 -0.2 0.3
Angina 0.4 0.5 3.4 0.3 0.6 0.6 0.6 1.0 1.0 0.8 0.8 1.8 1.5 0.0 0.6 0.6 0.7 0.5 0.7 1.1 0.6 1.1 0.4 0.2 0.8 0.7 0.7 0.6 1.1 0.7 0.6 0.3 0.5 -0.6 0.6 0.6 0.7 0.5 0.2 -0.1 0.4 0.5 0.3 0.4 0.7 0.5 0.9 0.9 1.0 0.4 -0.9 0.8
Medication for hormone replacement therapy 0.3 0.3 3.2 -1.8 -0.1 -0.2 -0.3 -0.8 -0.2 0.1 -0.6 -0.4 -0.4 0.0 -0.2 -0.1 -0.4 -0.9 -0.4 -0.2 -0.1 -0.6 -0.4 -0.4 -0.5 -0.6 -0.7 -0.1 1.0 -0.6 -0.2 -0.9 -0.3 -0.1 -0.8 -0.2 -0.8 -0.7 -0.3 0.8 -0.4 0.3 -1.0 -1.0 -0.3 -0.3 0.6 -0.6 0.4 -0.2 -0.8 -0.2
Vitamin and mineral supplements 0.2 0.2 1.2 0.6 0.1 0.0 0.2 0.0 -0.2 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.2 -0.7 0.1 0.3 0.1 0.8 -0.1 -0.1 0.1 0.5 0.3 0.1 0.6 0.3 0.1 -1.1 0.1 0.1 0.9 0.5 0.4 0.8 -0.0 0.5 0.2 0.8 0.3 0.3 1.0 -0.0 0.4 0.8 0.3 -0.2 -0.1 0.3
Supplements: Zinc 2.7 2.9 6.5 0.9 1.8 1.8 1.9 0.7 1.6 1.8 1.6 1.5 0.8 0.0 1.9 1.8 1.7 1.6 1.8 1.1 1.8 1.5 1.5 1.4 1.4 1.7 1.7 1.8 1.6 1.7 1.8 2.1 1.9 -1.5 1.6 2.1 1.6 2.2 2.0 2.5 1.7 2.2 1.8 1.6 2.3 1.7 1.7 1.8 1.4 1.3 2.1 1.7
Medication: Co-codamol 1.8 2.1 6.4 -1.3 -1.5 -1.6 -1.7 -1.5 -2.5 -1.7 -1.7 -0.4 -0.3 0.0 -1.6 -1.6 -1.6 -2.2 -1.6 -1.2 -1.6 -1.3 -1.4 -1.2 -1.3 -1.6 -1.6 -1.5 -0.8 -1.5 -1.5 -0.8 -1.6 1.7 -1.2 -1.5 -1.5 -1.6 -1.6 -0.8 -1.6 -0.9 -1.6 -1.6 -1.4 -1.5 -1.1 -1.5 -1.2 -1.4 -1.1 -1.6
Medication: Metformin 0.4 0.6 4.9 -0.3 -0.3 -0.3 -0.1 -0.2 1.1 0.7 -0.0 2.2 2.1 0.0 -0.3 -0.4 -0.0 0.3 -0.1 0.3 -0.4 1.4 -0.7 -0.9 -0.1 -0.0 0.1 -0.4 1.4 -0.0 -0.3 -1.0 -0.4 0.2 0.8 0.1 0.0 0.5 -0.7 -0.1 -0.6 1.0 -0.4 -0.3 1.1 -0.5 0.5 1.1 0.4 -0.9 -1.7 -0.3
Diabetes (father) 0.6 0.8 2.8 -0.7 -0.9 -0.9 -0.9 -1.3 -1.3 -1.0 -1.2 0.8 0.2 0.0 -0.9 -0.9 -1.1 -1.7 -1.0 -0.8 -0.9 -0.9 -1.0 -0.7 -0.7 -1.1 -0.9 -0.9 -0.5 -0.8 -0.9 -0.5 -0.9 1.0 -0.4 -0.7 -0.7 -1.1 -0.9 -0.2 -1.1 -0.6 -1.1 -1.2 -0.6 -1.0 -0.2 -0.8 -0.7 -0.9 -0.8 -0.9
Diabetes (mother) 1.6 2.0 5.9 0.9 1.2 1.2 1.3 1.6 1.8 1.7 1.7 0.9 2.4 0.0 1.2 1.2 1.4 1.4 1.3 1.6 1.1 2.1 1.0 0.8 1.3 1.6 1.5 1.2 2.2 1.4 1.2 1.0 1.1 -1.2 1.9 1.5 1.5 1.6 0.9 1.3 1.2 1.5 1.0 1.2 1.9 1.2 1.7 1.9 1.9 1.0 -0.4 1.5
Severe depression (siblings) 2.3 2.5 4.9 -0.9 -2.1 -2.0 -1.9 -1.3 -1.8 -1.3 -1.5 -0.5 -0.1 0.0 -2.0 -2.0 -1.8 -1.4 -1.8 -1.4 -2.1 -0.7 -2.0 -1.5 -1.7 -1.6 -1.7 -2.1 -1.1 -1.7 -2.1 -0.8 -2.0 2.2 -0.9 -1.8 -1.6 -1.1 -2.1 -1.4 -1.7 -0.7 -1.5 -1.5 -1.0 -1.9 -1.4 -1.0 -1.7 -2.0 -1.6 -1.7
Pack years adult smoking proportion 1.3 1.9 4.2 -2.0 -1.3 -1.3 -1.2 -1.3 -1.1 -1.7 -1.4 -0.9 -2.1 0.0 -1.2 -1.3 -1.5 -1.9 -1.4 -1.5 -1.3 -1.9 -1.0 -1.1 -1.5 -1.5 -1.7 -1.3 -1.4 -1.6 -1.3 -0.5 -1.2 1.1 -2.0 -1.2 -1.8 -1.7 -1.0 -1.1 -1.2 -1.2 -1.4 -1.4 -1.9 -1.3 -1.1 -1.9 -1.6 -1.0 0.2 -1.1
Impedance of leg (right) 0.5 2.2 9.2 -2.5 -0.8 -0.9 -1.2 -1.6 -0.6 -1.0 -1.6 -0.2 -2.1 0.0 -0.9 -0.8 -1.4 -0.9 -1.3 -0.8 -0.8 -2.8 -0.9 -0.6 -0.9 -1.6 -1.8 -0.8 -0.9 -1.7 -0.9 -1.8 -1.0 0.6 -3.0 -1.6 -1.9 -3.0 -0.9 -0.6 -1.0 -1.6 -2.0 -2.2 -2.7 -1.1 -0.5 -2.8 -0.7 -0.2 -0.8 -0.7
Leg fat-free mass (left) 0.3 1.6 3.0 1.7 1.1 1.2 1.2 1.2 0.5 1.2 1.2 0.7 1.3 0.0 1.1 1.1 1.3 0.4 1.3 1.1 1.1 1.6 1.3 1.3 1.3 1.3 1.3 1.1 0.7 1.5 1.2 1.5 1.2 -1.3 1.7 1.5 1.4 1.6 1.4 1.4 1.4 1.5 1.6 1.6 1.3 1.3 1.2 1.4 0.9 1.1 1.7 1.2
Trunk fat percentage 0.1 0.2 1.7 -0.3 0.3 0.3 0.4 0.7 -0.6 0.2 -0.0 1.3 0.2 0.0 0.3 0.3 0.1 0.1 0.2 0.3 0.3 -0.1 0.4 -0.1 0.3 -0.0 0.2 0.3 0.4 0.2 0.2 1.1 0.2 -0.6 -0.2 -0.3 0.2 -0.9 -0.1 -0.4 0.1 -0.8 -0.4 -0.2 -0.7 0.3 0.6 -0.4 0.7 0.7 -1.2 0.3
Hand grip strength (right) 0.8 2.2 11.4 2.2 1.4 1.6 1.5 1.0 0.0 1.1 1.5 -0.4 -1.6 0.0 1.5 1.5 1.6 0.7 1.6 0.4 1.5 0.5 1.9 2.4 1.1 1.7 1.5 1.5 -1.5 1.5 1.5 0.7 1.7 -0.9 0.7 1.5 1.6 1.7 2.1 -0.4 1.7 -0.5 2.4 2.3 0.4 1.6 -0.5 0.9 -0.0 1.5 3.4 1.1
Townsend deprivation index at recruitment 0.1 0.2 1.2 -1.0 -0.0 -0.1 -0.2 0.1 0.2 -0.2 -0.2 -1.1 -0.5 0.0 -0.2 -0.1 -0.3 -0.8 -0.2 -0.0 -0.1 -0.5 -0.3 -0.7 -0.3 -0.4 -0.6 -0.1 0.7 -0.5 -0.1 -0.6 -0.1 -0.2 -0.8 0.0 -0.8 -0.1 -0.0 0.7 -0.2 0.5 -0.5 -0.6 0.0 -0.2 0.2 -0.4 0.1 -0.3 0.0 -0.0
Current tobacco smoking 3.2 5.2 11.6 -2.3 -2.5 -2.5 -2.4 -3.0 -2.2 -2.6 -2.4 -3.4 -1.7 0.0 -2.5 -2.5 -2.6 -2.9 -2.5 -2.4 -2.5 -2.0 -2.4 -3.0 -2.7 -2.5 -2.6 -2.6 -1.5 -2.6 -2.6 -1.1 -2.5 2.3 -1.9 -2.0 -2.7 -1.6 -2.2 -0.5 -2.2 -0.4 -2.0 -2.2 -1.6 -2.5 -1.9 -2.1 -2.4 -2.5 -0.5 -2.4
Average weekly fortified wine intake 0.1 0.1 1.1 -0.4 0.2 0.2 0.2 -0.5 0.4 0.3 0.1 0.2 0.8 0.0 0.1 0.2 0.2 -0.3 0.2 0.4 0.2 0.3 0.1 -0.0 0.3 0.1 0.1 0.2 0.7 0.1 0.2 0.0 0.1 -0.5 0.0 0.1 0.1 -0.4 -0.1 -0.4 -0.0 -0.0 -0.4 -0.3 -0.1 0.0 0.7 0.2 0.5 0.1 -1.0 0.3
Maternal smoking around birth 1.3 2.0 9.1 -0.6 -1.6 -1.5 -1.4 -1.6 -1.3 -1.6 -1.3 -3.0 -1.3 0.0 -1.6 -1.5 -1.4 -1.7 -1.4 -1.4 -1.5 -1.2 -1.5 -1.5 -1.6 -1.4 -1.6 -1.6 -1.3 -1.5 -1.5 -1.1 -1.5 1.5 -1.3 -1.1 -1.8 -0.5 -1.1 -0.6 -1.2 0.0 -0.8 -1.0 -0.7 -1.5 -1.5 -1.0 -1.9 -1.7 0.5 -1.4
Fed-up feelings 3.2 5.7 12.5 -2.7 -2.6 -2.7 -2.7 -2.8 -2.8 -2.3 -2.5 -2.7 -0.8 0.0 -2.7 -2.7 -2.6 -3.5 -2.7 -2.0 -2.7 -1.9 -3.1 -3.2 -2.6 -2.6 -2.8 -2.7 -1.0 -2.7 -2.7 -2.2 -2.6 2.5 -1.9 -1.6 -3.0 -1.1 -2.3 0.0 -2.5 0.7 -2.2 -2.6 -0.6 -2.9 -1.6 -1.5 -2.8 -3.3 -0.2 -2.5
Frequency of unenthusiasm / disinterest in last 2 weeks 2.6 3.4 8.0 -1.8 -2.2 -2.3 -2.4 -1.7 -1.8 -1.5 -1.9 -1.7 0.6 0.0 -2.2 -2.3 -2.2 -2.6 -2.2 -1.2 -2.3 -0.8 -2.8 -2.5 -2.0 -1.9 -2.0 -2.3 -0.3 -1.9 -2.3 -1.0 -2.2 2.7 -0.4 -1.3 -2.0 -0.5 -2.1 0.9 -1.9 1.3 -1.6 -2.0 0.4 -2.5 -1.0 -0.6 -1.8 -2.8 -0.8 -2.0
Relative age voice broke 0.7 1.1 2.4 0.5 1.2 1.2 1.2 0.4 1.1 0.9 0.9 1.4 0.3 0.0 1.2 1.2 1.2 0.5 1.2 0.7 1.2 0.6 1.0 1.4 1.1 1.0 1.0 1.2 0.6 1.0 1.2 0.0 1.2 -0.8 0.8 1.0 0.9 1.0 1.4 1.5 1.3 1.3 1.2 1.0 1.0 1.0 0.9 0.9 0.5 1.0 1.6 1.0
Taking other prescription medications 1.2 1.8 3.6 -1.4 -1.6 -1.7 -1.4 -1.4 -0.8 -1.2 -1.3 -0.6 0.0 0.0 -1.6 -1.7 -1.4 -1.7 -1.5 -1.0 -1.7 -0.4 -1.8 -1.8 -1.5 -1.4 -1.3 -1.6 -0.4 -1.4 -1.6 -0.9 -1.6 1.9 -0.7 -1.6 -1.3 -0.9 -1.8 -0.8 -1.5 -0.2 -1.4 -1.4 -0.6 -1.7 -1.1 -0.7 -1.2 -1.7 -1.9 -1.5
Age when periods started (menarche) 0.0 0.1 0.7 -0.2 -0.2 -0.2 -0.2 0.1 -0.8 -0.4 -0.3 -0.7 -0.4 0.0 -0.1 -0.2 -0.3 -0.4 -0.3 -0.2 -0.2 -0.6 -0.1 -0.1 -0.2 -0.3 -0.4 -0.2 -0.4 -0.3 -0.2 0.2 -0.1 0.3 -0.4 -0.3 -0.3 -0.5 -0.1 0.1 -0.2 -0.3 -0.2 -0.3 -0.6 -0.1 -0.3 -0.6 -0.2 -0.0 0.3 -0.2
Bilateral oophorectomy (both ovaries removed) 0.3 0.4 2.4 -0.3 -0.4 -0.4 -0.5 -0.2 -0.9 -0.7 -0.6 0.8 -0.1 0.0 -0.4 -0.4 -0.5 -0.4 -0.5 -0.4 -0.4 -0.7 0.1 0.0 -0.1 -0.6 -0.4 -0.4 -0.6 -0.4 -0.4 -0.7 -0.4 0.3 -0.7 -0.8 -0.3 -1.1 -0.6 -1.0 -0.5 -1.6 -0.6 -0.4 -1.3 -0.2 -0.4 -1.0 -0.0 0.2 -1.0 -0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 1.2 0.9 -0.0 0.0 0.0 0.3 -0.8 0.4 0.3 0.6 0.2 0.0 0.0 0.0 0.2 0.3 0.1 0.2 -0.0 0.3 0.4 0.8 0.2 0.4 0.3 0.0 -0.6 0.3 0.0 1.1 0.1 0.2 0.4 -0.2 0.5 -0.0 -0.0 -0.9 0.2 -0.8 0.5 0.6 -0.5 0.1 -0.7 0.0 0.1 0.3 -0.2 -0.0
Tinnitus: Yes, but not now, but have in the past 3.2 3.4 5.7 -1.2 -1.8 -1.8 -2.0 -1.9 -2.0 -1.9 -2.0 -1.3 -1.7 0.0 -1.8 -1.8 -1.9 -0.9 -1.9 -1.5 -1.8 -2.0 -1.7 -1.6 -1.7 -2.1 -1.9 -1.8 -1.6 -2.1 -1.8 -1.6 -1.9 1.6 -2.4 -2.3 -2.0 -2.3 -1.9 -2.1 -1.7 -1.9 -1.9 -1.8 -2.4 -1.8 -1.9 -2.2 -1.7 -1.4 -1.7 -1.9
Qualifications: CSEs or equivalent 1.5 2.0 8.2 -1.2 -1.5 -1.6 -1.5 -1.1 -1.0 -0.9 -1.1 -0.0 0.5 0.0 -1.6 -1.6 -1.5 -1.7 -1.5 -1.0 -1.6 -0.4 -2.1 -1.9 -1.5 -1.3 -1.3 -1.6 0.4 -1.4 -1.6 -2.0 -1.7 1.4 -0.7 -1.4 -1.3 -1.2 -2.0 -1.0 -1.8 -0.3 -2.0 -1.9 -0.2 -1.7 -0.3 -0.5 -0.9 -1.9 -2.9 -1.1
Serious illness, injury or assault to yourself 0.6 0.7 4.7 -0.2 -0.8 -0.8 -0.8 -0.6 -1.5 -1.0 -0.6 -2.2 -0.9 0.0 -0.9 -0.8 -0.8 -1.5 -0.8 -0.6 -0.8 -0.7 -0.5 -1.2 -1.0 -0.7 -0.8 -0.8 -1.1 -0.7 -0.8 -0.6 -0.7 0.5 -0.6 -0.4 -0.9 0.1 -0.4 0.1 -0.4 0.2 0.0 -0.2 -0.4 -0.7 -1.2 -0.6 -1.2 -0.8 1.2 -0.9
High blood pressure 1.2 3.3 18.5 0.4 1.0 0.9 1.1 1.2 2.5 2.5 1.7 3.0 4.3 0.0 0.8 0.8 1.4 1.3 1.2 2.3 0.8 3.5 0.5 0.1 1.2 1.6 1.6 0.8 3.6 1.5 0.9 0.9 0.7 -1.4 2.9 1.2 1.6 1.7 0.1 1.6 1.1 2.7 0.7 1.0 2.5 0.7 2.3 2.7 2.4 0.5 -2.3 1.3
Hayfever, allergic rhinitis or eczema 0.1 0.3 1.2 0.2 -0.6 -0.7 -0.8 -0.6 -0.6 -0.5 -0.8 -1.1 0.1 0.0 -0.6 -0.6 -0.8 -0.3 -0.7 -0.8 -0.6 -0.6 -0.6 -0.2 -0.2 -0.7 -0.6 -0.6 -0.4 -0.5 -0.7 -0.4 -0.6 0.7 -0.1 -0.4 -0.4 -0.2 -0.6 -0.0 -0.9 -0.6 -0.6 -0.6 -0.1 -0.5 -0.4 -0.4 -0.5 -0.7 -0.2 -0.8
Multivitamins +/- minerals 0.8 1.0 3.2 -1.4 -0.8 -0.8 -0.8 -0.8 -1.0 -1.0 -1.2 -0.5 -1.4 0.0 -0.8 -0.8 -0.9 -0.0 -0.9 -1.0 -0.8 -1.3 -0.6 -0.4 -0.8 -1.2 -1.1 -0.8 -0.9 -1.1 -0.8 0.4 -0.9 0.5 -1.7 -1.2 -1.2 -1.6 -0.8 -1.5 -1.0 -1.5 -1.2 -1.1 -1.8 -0.7 -0.9 -1.5 -0.9 -0.5 -0.8 -1.0
Stomach or abdominal pain in last month 0.8 1.0 5.2 -0.8 -0.8 -0.9 -0.7 -0.6 -0.9 0.4 -0.0 0.8 2.3 0.0 -0.9 -0.9 -0.5 -1.8 -0.6 0.2 -0.9 1.5 -1.1 -1.9 -0.8 -0.1 -0.3 -0.9 1.7 -0.3 -0.8 0.2 -0.9 0.6 1.3 -0.0 -0.3 0.8 -1.1 1.2 -0.5 2.2 -0.4 -0.4 1.4 -1.0 0.6 1.1 0.2 -1.3 -1.6 -0.4
Supplements: Glucosamine 0.6 0.7 4.1 0.6 -0.7 -0.6 -0.7 -0.5 -1.2 -1.3 -0.8 -0.9 -1.1 0.0 -0.6 -0.6 -0.7 -0.5 -0.6 -1.0 -0.6 -1.1 -0.2 -0.0 -0.4 -0.7 -0.5 -0.6 -1.7 -0.6 -0.6 0.3 -0.6 0.5 -0.8 -1.1 -0.3 -1.3 -0.6 -1.7 -0.6 -2.0 -0.5 -0.4 -1.6 -0.4 -1.1 -1.2 -0.9 -0.1 -0.4 -0.7
Diverticular disease/diverticulitis (self-reported) 0.1 0.1 1.4 -0.1 0.1 0.0 -0.1 0.3 0.0 0.1 -0.1 1.2 0.6 0.0 0.1 0.0 0.0 -0.9 0.0 0.4 0.1 0.1 -0.2 -0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.1 0.4 0.1 0.4 0.2 0.0 0.2 0.2 -0.1 0.3 -0.1 0.2 -0.1 -0.1 0.6 0.0 0.3 0.3 0.2 -0.1 -0.5 -0.0
Medication: Atenolol 0.5 0.7 1.6 -1.1 -1.0 -1.0 -1.0 -0.3 -0.7 -0.7 -0.8 -1.2 0.7 0.0 -1.0 -1.0 -0.9 -1.2 -1.0 -0.1 -1.0 -0.2 -1.0 -1.3 -0.9 -0.9 -0.8 -1.0 0.2 -0.8 -1.0 -0.5 -1.0 0.6 -0.1 -0.7 -0.8 -0.6 -1.0 0.2 -0.8 0.4 -0.8 -0.9 -0.3 -1.0 -0.2 -0.4 -0.4 -0.9 -0.9 -0.8
Medication: Levothyroxine sodium 0.2 0.4 1.0 -0.3 0.8 0.7 0.7 0.2 1.0 1.0 0.5 -0.2 -0.2 0.0 0.7 0.7 0.6 -0.2 0.7 0.5 0.7 0.4 0.4 0.3 0.4 0.5 0.4 0.8 1.0 0.4 0.7 0.2 0.7 -1.0 0.1 0.9 0.3 0.7 0.7 1.0 0.5 0.8 0.3 0.3 0.8 0.6 0.8 0.5 0.8 0.4 0.6 0.6
Sitting height 0.3 1.9 15.1 1.1 1.5 1.5 1.3 0.6 0.2 0.8 0.7 -0.1 -1.0 0.0 1.6 1.6 1.2 0.1 1.3 0.7 1.5 -0.2 1.9 2.5 1.2 1.0 1.0 1.6 -0.7 1.3 1.5 1.4 1.7 -1.1 0.4 1.8 1.0 0.9 2.2 1.7 1.7 0.7 1.8 1.5 0.2 1.5 0.8 0.2 0.3 1.7 3.9 1.2
Chronic bronchitis/emphysema (father) 0.0 0.1 0.4 -0.0 -0.1 -0.1 -0.1 -0.1 -0.1 -0.1 0.0 -0.1 -0.5 0.0 -0.2 -0.1 -0.1 -0.2 -0.1 0.2 -0.1 -0.3 0.1 -0.4 -0.5 -0.0 -0.2 -0.1 -0.2 -0.1 -0.1 -0.6 -0.0 0.1 -0.2 -0.0 -0.3 -0.2 0.1 0.5 0.3 0.3 0.2 0.0 -0.3 -0.0 -0.1 -0.3 -0.1 0.2 0.7 0.1
High blood pressure (mother) 0.5 0.8 7.8 -0.5 -0.0 -0.1 -0.1 -0.4 0.9 1.1 0.3 1.0 2.8 0.0 -0.1 -0.1 0.1 0.2 0.0 1.2 -0.2 1.5 -0.7 -0.6 0.3 0.2 0.2 -0.1 2.2 0.2 -0.1 0.1 -0.3 -0.2 1.1 0.1 0.2 0.1 -0.7 0.8 -0.2 1.3 -0.6 -0.5 1.1 -0.2 1.2 1.0 1.2 -0.3 -2.5 0.4
Body mass index (BMI) 0.4 1.9 5.1 1.7 1.1 1.1 1.4 1.9 0.5 1.2 1.4 1.9 2.2 0.0 1.1 1.1 1.4 1.3 1.3 1.2 1.1 2.1 1.2 0.6 1.3 1.4 1.8 1.1 1.4 1.6 1.1 2.2 1.0 -1.2 2.1 0.7 2.0 1.1 0.5 -0.2 0.9 0.0 0.9 1.4 1.3 1.3 1.2 1.8 1.7 1.2 -1.5 1.1
Impedance of leg (left) 0.4 1.9 8.8 -2.6 -0.6 -0.7 -1.0 -1.6 -0.7 -0.9 -1.5 -0.2 -2.4 0.0 -0.7 -0.6 -1.2 -0.8 -1.1 -0.8 -0.6 -2.7 -0.9 -0.6 -1.0 -1.5 -1.7 -0.6 -0.8 -1.6 -0.7 -1.6 -0.8 0.6 -3.0 -1.3 -1.8 -2.7 -0.6 -0.4 -0.9 -1.3 -1.8 -2.1 -2.3 -1.0 -0.5 -2.5 -0.7 -0.2 -0.4 -0.6
Leg predicted mass (left) 0.3 1.7 3.0 1.7 1.2 1.2 1.3 1.2 0.5 1.3 1.2 0.6 1.3 0.0 1.2 1.2 1.4 0.5 1.4 1.1 1.2 1.6 1.4 1.3 1.3 1.3 1.4 1.2 0.8 1.5 1.2 1.5 1.3 -1.3 1.7 1.6 1.4 1.6 1.4 1.4 1.5 1.5 1.6 1.6 1.3 1.3 1.2 1.5 0.9 1.1 1.7 1.2
Trunk fat mass 0.1 0.5 2.3 0.5 0.8 0.8 0.9 1.2 -0.4 0.6 0.5 1.5 0.5 0.0 0.8 0.8 0.7 0.3 0.8 0.8 0.8 0.5 1.0 0.6 0.8 0.6 0.8 0.8 0.4 0.8 0.8 1.5 0.8 -1.1 0.4 0.3 0.9 -0.2 0.6 -0.1 0.7 -0.4 0.3 0.5 -0.2 0.8 0.9 0.2 1.0 1.2 -0.4 0.8
Waist circumference 0.2 0.7 4.3 0.9 0.6 0.6 0.8 1.0 -0.2 0.6 0.7 2.1 1.5 0.0 0.6 0.6 0.7 0.3 0.7 0.8 0.6 1.2 0.7 0.3 0.8 0.7 1.0 0.6 0.7 1.0 0.6 1.6 0.6 -0.6 1.3 0.5 1.1 0.7 0.4 0.3 0.7 0.3 0.7 0.8 0.8 0.7 0.8 1.0 0.9 0.7 -0.4 0.6
Number of incorrect matches in round 0.2 0.4 2.2 -0.5 -0.5 -0.6 -0.6 -1.2 0.2 -0.3 -0.8 -0.2 0.8 0.0 -0.5 -0.6 -0.7 -0.3 -0.7 -0.4 -0.6 -0.4 -0.8 -1.0 -0.4 -0.7 -0.5 -0.6 0.4 -0.5 -0.6 0.0 -0.7 0.5 -0.0 -0.7 -0.3 -0.6 -0.8 0.4 -0.9 -0.1 -1.0 -1.0 0.1 -0.8 0.1 -0.3 -0.0 -0.7 -1.5 -0.7
Past tobacco smoking 0.7 1.3 6.4 -0.0 1.2 1.2 0.7 1.2 2.0 1.0 0.7 2.5 1.5 0.0 1.1 1.2 0.9 1.7 1.0 1.6 1.2 0.5 0.9 1.3 1.4 0.7 1.0 1.2 1.8 0.9 1.2 0.3 1.0 -1.5 0.5 0.7 1.1 -0.7 0.6 0.4 0.5 -0.3 -0.4 -0.2 0.1 1.1 2.0 0.4 2.0 1.4 -1.6 1.3
Alcohol usually taken with meals 0.3 0.4 2.4 0.2 0.7 0.6 0.6 0.3 1.1 0.9 0.5 1.4 0.5 0.0 0.7 0.6 0.6 1.2 0.6 0.4 0.7 0.5 0.4 0.7 0.6 0.5 0.7 0.6 1.0 0.5 0.6 0.4 0.5 -0.5 0.4 0.1 0.8 -0.4 0.1 -0.4 0.2 -0.5 -0.3 -0.1 0.1 0.5 1.0 0.4 1.0 0.7 -1.6 0.7
Nervous feelings 0.1 0.3 1.2 -0.9 -0.5 -0.5 -0.5 -0.4 -0.3 -0.1 -0.3 0.4 1.1 0.0 -0.4 -0.5 -0.3 -0.8 -0.4 0.1 -0.5 0.3 -0.9 -0.7 -0.2 -0.3 -0.3 -0.5 0.5 -0.4 -0.5 -0.3 -0.5 0.6 0.1 -0.0 -0.5 0.3 -0.6 0.2 -0.6 0.9 -0.5 -0.6 0.7 -0.7 0.0 0.5 -0.4 -1.1 -0.5 -0.4
Frequency of tenseness / restlessness in last 2 weeks 2.2 3.5 8.6 -1.1 -2.4 -2.4 -2.3 -1.6 -1.9 -1.9 -1.7 -2.0 0.6 0.0 -2.4 -2.4 -2.1 -2.2 -2.2 -1.2 -2.4 -0.5 -2.8 -2.8 -2.3 -1.7 -1.8 -2.4 -0.7 -1.8 -2.4 -0.9 -2.3 2.7 -0.1 -1.6 -1.7 -0.3 -2.4 -0.3 -2.0 0.8 -1.4 -1.7 0.4 -2.5 -1.4 -0.3 -2.1 -2.9 -1.4 -2.0
Hearing difficulty/problems with background noise 1.0 1.5 5.0 1.6 0.9 1.0 1.3 0.8 0.7 1.1 1.4 -0.4 0.4 0.0 1.0 1.0 1.4 1.2 1.3 0.7 1.0 1.6 1.1 0.9 0.7 1.5 1.4 1.0 -0.2 1.4 1.0 0.1 1.1 -0.6 1.8 1.3 1.4 2.2 1.3 0.8 1.5 1.5 2.2 2.0 1.7 0.9 0.1 1.8 0.2 0.7 2.1 0.9
Hair/balding pattern: Pattern 2 1.3 1.7 4.2 0.7 1.5 1.5 1.4 1.4 1.2 1.2 1.0 1.6 0.7 0.0 1.6 1.5 1.4 1.6 1.4 1.6 1.5 0.5 1.4 2.0 1.7 1.1 1.1 1.6 0.8 1.2 1.5 1.6 1.5 -1.3 0.4 1.1 1.1 0.5 1.5 1.2 1.6 0.9 1.1 1.0 0.5 1.4 1.2 0.6 1.2 1.7 1.1 1.4
Had menopause 1.3 1.6 4.1 0.8 1.4 1.4 1.5 1.2 1.2 0.9 1.1 0.5 0.1 0.0 1.4 1.4 1.4 1.5 1.4 1.0 1.4 0.7 2.0 1.8 1.4 1.2 1.2 1.4 0.4 1.3 1.4 1.2 1.4 -1.5 0.7 1.1 1.1 0.8 1.6 1.0 1.7 0.5 1.6 1.6 0.0 1.6 0.8 0.4 1.2 2.0 1.7 1.1
Had other major operations 0.3 0.4 1.6 0.8 0.5 0.4 0.7 0.9 0.7 0.6 0.7 0.5 1.3 0.0 0.5 0.4 0.6 -0.1 0.6 0.8 0.5 1.1 0.5 0.1 0.8 0.7 0.8 0.5 0.9 0.7 0.5 0.9 0.4 -0.7 1.0 0.3 0.9 0.5 0.2 0.1 0.4 0.2 0.3 0.6 0.7 0.7 0.6 0.9 0.9 0.6 -0.8 0.5
Forced vital capacity (FVC) 0.8 2.9 35.9 1.3 -0.4 -0.2 -0.2 -0.8 -1.5 -1.6 -0.5 -4.5 -4.5 0.0 -0.2 -0.2 -0.3 -1.1 -0.3 -1.8 -0.2 -2.1 0.5 0.8 -1.0 -0.3 -0.6 -0.2 -4.1 -0.4 -0.2 -0.1 0.2 1.1 -1.2 0.1 -0.8 0.7 1.3 0.3 0.7 -0.3 1.8 1.2 -1.0 0.0 -2.5 -1.4 -2.8 0.0 6.0 -0.6
Heel bone mineral density (BMD) T-score, automated (right) 0.1 0.3 1.5 1.2 0.3 0.3 0.2 0.6 -1.0 0.8 0.7 0.6 0.3 0.0 0.3 0.3 0.5 0.1 0.4 0.6 0.3 0.7 0.5 0.8 0.2 0.7 0.6 0.3 -0.2 0.6 0.3 0.7 0.3 -0.2 0.9 0.3 0.8 0.4 0.3 0.0 0.6 -0.0 0.8 0.8 0.1 0.3 -0.2 0.4 0.4 0.5 0.2 0.4
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 1.7 0.3 -0.9 -0.8 -0.6 -0.3 -0.4 -1.0 -0.6 -1.0 -0.3 0.0 -0.8 -0.9 -0.6 -0.5 -0.7 -0.7 -0.9 -0.3 -0.6 -0.8 -0.7 -0.6 -0.6 -0.8 -1.0 -0.6 -0.8 0.5 -0.8 0.9 -0.4 -0.8 -0.6 -0.0 -0.8 -1.0 -0.6 -0.6 -0.1 -0.0 -0.4 -0.8 -1.3 -0.4 -0.8 -0.8 -0.4 -1.0
Qualifications: None of the above 0.6 1.3 4.9 -1.7 -1.1 -1.1 -1.1 -0.6 -1.4 -1.4 -1.2 -2.2 -0.9 0.0 -1.1 -1.1 -1.2 -2.2 -1.2 -0.6 -1.0 -1.4 -0.8 -1.3 -1.1 -1.3 -1.5 -1.1 -0.8 -1.3 -1.1 0.4 -1.0 0.5 -1.5 -1.0 -1.6 -1.4 -0.8 -0.1 -0.8 -0.2 -1.0 -1.2 -1.6 -1.0 -0.6 -1.6 -1.1 -0.6 0.3 -0.9
Financial difficulties in last 2 years 0.6 0.8 4.6 -0.8 -0.5 -0.5 -0.7 -0.4 -1.6 -0.8 -0.7 -2.1 -1.8 0.0 -0.5 -0.5 -0.7 -1.4 -0.6 -0.2 -0.5 -1.2 -0.5 -0.9 -1.2 -0.7 -1.1 -0.4 -0.8 -0.7 -0.5 -0.9 -0.3 0.3 -1.1 -0.1 -1.2 -0.3 0.2 1.3 0.0 1.2 -0.0 -0.5 -0.3 -0.6 -0.3 -1.0 -1.1 -0.5 2.2 -0.2
Mouth/teeth dental problems 0.2 0.4 3.1 0.4 0.3 0.3 0.2 1.2 1.6 0.0 0.2 1.2 0.6 0.0 0.3 0.3 0.2 1.8 0.2 0.1 0.3 0.3 0.5 0.8 0.3 0.3 0.4 0.3 0.6 0.4 0.3 0.9 0.2 0.1 0.6 0.1 0.6 -0.2 -0.0 -0.1 -0.0 -0.8 -0.2 0.1 -0.0 0.5 0.7 0.1 1.0 0.6 -1.1 0.3
Heart attack 1.5 1.9 3.4 -0.9 -1.8 -1.7 -1.7 -0.9 -1.3 -0.9 -1.0 0.1 0.2 0.0 -1.8 -1.8 -1.5 -1.6 -1.5 -1.2 -1.8 -0.3 -1.6 -1.7 -1.5 -1.1 -1.3 -1.8 -0.7 -1.4 -1.7 -1.3 -1.7 1.7 -0.7 -1.4 -1.3 -0.9 -1.8 -1.5 -1.6 -0.6 -1.3 -1.2 -0.8 -1.8 -1.1 -0.8 -1.4 -1.8 -1.5 -1.3
Allergy 0.4 0.9 2.1 0.5 1.0 1.0 1.0 0.7 1.2 0.9 1.2 1.4 0.3 0.0 0.9 1.0 1.1 0.7 1.1 1.3 1.0 1.0 0.9 0.7 0.6 1.1 1.0 1.0 0.4 1.0 1.0 0.8 1.0 -0.8 0.7 0.9 0.8 0.8 1.1 0.9 1.4 1.4 1.3 1.0 0.7 0.7 0.7 0.9 0.5 0.9 1.2 1.2
Pain all over the body in last month 0.2 0.2 1.5 -0.7 -0.2 -0.2 -0.1 -0.7 0.6 0.2 -0.2 -0.7 0.4 0.0 -0.2 -0.2 -0.2 0.2 -0.2 -0.1 -0.2 -0.1 -0.3 -0.6 -0.2 -0.2 -0.4 -0.2 0.4 -0.3 -0.2 0.2 -0.1 0.0 -0.1 0.4 -0.5 0.2 0.1 1.2 -0.2 1.2 -0.2 -0.4 0.5 -0.3 0.5 0.0 -0.3 -0.5 0.9 -0.0
Diabetes (self-reported) 0.8 1.3 6.8 -0.3 -1.2 -1.3 -1.0 -0.6 0.0 0.1 -0.3 1.5 2.5 0.0 -1.3 -1.3 -0.7 -0.6 -0.8 -0.1 -1.3 1.6 -1.6 -1.6 -0.8 -0.4 -0.3 -1.3 1.0 -0.5 -1.2 -1.4 -1.3 1.1 1.0 -0.7 -0.3 0.5 -1.7 -0.8 -1.4 0.9 -0.8 -0.7 1.2 -1.4 -0.3 1.2 -0.4 -2.0 -2.6 -1.0
Hayfever/allergic rhinitis (self-reported) 1.1 1.5 3.7 -1.0 -1.4 -1.4 -1.6 -1.5 -0.9 -1.0 -1.5 -0.3 0.1 0.0 -1.4 -1.4 -1.5 -1.1 -1.4 -1.2 -1.4 -0.7 -1.3 -1.3 -1.5 -1.4 -1.3 -1.4 -0.0 -1.2 -1.4 -1.9 -1.4 1.1 -0.4 -1.0 -1.1 -1.1 -1.5 -0.1 -1.5 -0.4 -1.6 -1.5 -0.6 -1.3 -0.2 -0.8 -0.6 -1.4 -1.5 -1.3
Medication: Ramipril 0.2 0.2 1.3 0.7 0.0 0.1 0.2 0.6 0.5 0.7 0.5 0.5 1.1 0.0 0.0 0.0 0.3 -0.1 0.3 0.3 0.0 1.2 0.3 0.2 0.3 0.5 0.6 -0.0 0.3 0.5 0.0 0.0 0.0 -0.1 1.0 0.2 0.7 0.4 -0.1 -0.6 0.2 -0.1 0.4 0.7 0.3 0.3 0.1 0.7 0.5 0.2 -0.9 0.2
Medication: Simvastatin 0.8 1.2 6.8 0.2 0.6 0.6 0.8 1.1 1.1 1.7 1.1 1.6 2.6 0.0 0.6 0.5 0.9 1.0 0.8 1.3 0.6 2.1 0.4 0.2 0.9 1.0 1.0 0.5 2.0 1.0 0.6 1.4 0.5 -0.6 1.7 0.9 1.0 1.2 0.2 0.8 0.5 1.6 0.5 0.6 1.6 0.5 1.3 1.7 1.2 0.2 -0.9 0.9
Fluid intelligence score 0.1 0.2 1.0 0.5 0.3 0.3 0.3 0.6 0.6 0.4 0.4 0.5 -0.5 0.0 0.3 0.3 0.3 0.6 0.3 -0.2 0.3 0.2 0.4 0.8 0.3 0.4 0.4 0.3 -0.2 0.2 0.3 -0.7 0.2 -0.4 -0.1 -0.2 0.4 -0.2 0.1 -1.0 0.3 -0.9 0.2 0.4 -0.5 0.4 -0.2 -0.0 0.2 0.5 -0.5 0.3
Illnesses of siblings 0.3 0.4 2.5 -0.4 0.7 0.7 0.4 -0.3 -0.3 0.2 -0.1 -1.0 -1.4 0.0 0.7 0.7 0.3 0.3 0.4 -0.0 0.8 -1.0 0.7 0.8 0.5 0.0 -0.0 0.8 -0.2 0.2 0.7 -0.5 0.7 -1.0 -0.7 0.7 -0.0 -0.3 1.0 0.8 0.4 -0.1 0.2 -0.1 -0.4 0.7 0.4 -0.7 0.3 0.7 1.6 0.5
Neuroticism score 1.4 2.9 8.1 -1.8 -1.9 -2.0 -1.9 -2.1 -2.1 -1.1 -1.8 -1.0 0.6 0.0 -2.0 -2.0 -1.7 -2.5 -1.9 -1.1 -2.0 -0.5 -2.5 -2.5 -1.8 -1.7 -1.8 -2.0 -0.1 -1.7 -2.0 -1.7 -1.9 1.9 -0.6 -0.8 -2.0 -0.0 -1.7 0.6 -1.8 1.7 -1.4 -1.8 0.6 -2.3 -0.8 -0.3 -1.9 -2.8 -0.2 -1.9
Weight 0.4 1.9 4.1 1.4 1.5 1.5 1.6 1.7 0.4 1.4 1.3 1.8 1.3 0.0 1.5 1.5 1.5 0.7 1.5 1.4 1.4 1.4 1.7 1.5 1.6 1.4 1.6 1.5 0.9 1.6 1.5 2.0 1.5 -1.6 1.5 1.2 1.7 0.9 1.4 0.9 1.5 0.6 1.4 1.5 0.8 1.6 1.5 1.2 1.5 1.8 0.7 1.4
Impedance of arm (right) 0.3 1.3 5.5 -1.9 -0.7 -0.7 -0.9 -0.9 -0.2 -1.1 -1.3 -0.7 -1.6 0.0 -0.8 -0.7 -1.2 -0.7 -1.1 -0.6 -0.6 -2.2 -0.7 -0.5 -0.7 -1.3 -1.7 -0.6 -0.6 -1.4 -0.7 -1.6 -0.7 0.4 -2.4 -0.6 -1.8 -1.8 -0.4 0.4 -0.7 -0.3 -1.3 -1.6 -1.7 -0.9 -0.2 -2.1 -0.8 -0.4 0.7 -0.5
Arm fat percentage (right) 0.2 1.0 3.6 1.0 0.8 0.8 1.1 1.9 0.3 0.7 1.0 1.6 1.4 0.0 0.8 0.8 0.9 1.0 0.9 1.1 0.8 1.3 0.9 0.4 1.0 0.9 1.2 0.8 1.1 1.1 0.8 1.9 0.8 -1.2 1.2 0.4 1.3 0.2 0.4 -0.3 0.7 -0.2 0.4 0.8 0.4 1.0 1.1 0.9 1.4 1.1 -1.2 0.9
Trunk fat-free mass 0.3 1.9 4.0 1.9 1.4 1.4 1.4 1.1 0.7 1.5 1.2 0.7 0.9 0.0 1.4 1.4 1.5 0.4 1.5 1.3 1.4 1.3 1.7 1.9 1.5 1.4 1.5 1.4 0.5 1.6 1.4 1.4 1.5 -1.5 1.6 1.6 1.5 1.3 1.7 1.3 1.6 1.1 1.7 1.6 1.0 1.5 1.2 1.2 1.0 1.5 2.0 1.4
Hip circumference 1.1 4.9 6.9 2.0 2.4 2.4 2.4 2.5 1.6 2.2 2.1 2.6 2.4 0.0 2.4 2.3 2.3 2.2 2.4 2.2 2.3 2.3 2.3 2.0 2.5 2.1 2.5 2.3 2.2 2.5 2.3 2.2 2.3 -2.5 2.4 2.1 2.5 1.7 2.1 1.7 2.1 1.4 1.8 2.0 1.9 2.5 2.6 2.1 2.6 2.4 0.5 2.3
Time employed in main current job 1.1 1.3 5.0 -0.8 -1.1 -1.1 -1.2 -1.4 -0.9 -0.9 -1.1 -0.8 -1.9 0.0 -1.1 -1.1 -1.1 -1.0 -1.1 -1.3 -1.1 -1.2 -0.9 -0.9 -1.4 -1.1 -1.1 -1.1 -1.1 -1.2 -1.1 -2.2 -1.1 1.1 -1.3 -1.5 -1.1 -1.4 -1.1 -1.1 -0.7 -1.2 -1.0 -0.9 -1.5 -1.0 -1.0 -1.4 -1.0 -0.5 -0.9 -1.0
Alcohol intake versus 10 years previously 2.3 3.5 6.2 -1.7 -2.2 -2.3 -2.0 -1.5 -1.2 -1.9 -1.9 -0.4 -0.3 0.0 -2.3 -2.3 -2.0 -1.8 -2.1 -1.6 -2.3 -0.8 -2.3 -2.5 -2.1 -2.0 -1.8 -2.3 -0.8 -1.9 -2.2 -1.8 -2.3 2.2 -1.0 -2.1 -1.7 -1.4 -2.5 -1.8 -2.4 -1.0 -2.0 -1.9 -1.0 -2.2 -1.6 -1.0 -1.7 -2.4 -2.5 -2.2
Father’s age at death 3.8 5.1 9.7 1.9 2.7 2.6 2.6 2.3 2.8 2.1 2.3 3.0 1.3 0.0 2.6 2.6 2.4 3.1 2.5 2.4 2.6 1.6 2.6 2.7 2.6 2.3 2.4 2.7 1.9 2.4 2.6 1.6 2.5 -2.3 1.6 2.2 2.5 1.6 2.3 1.4 2.3 0.5 1.8 2.0 1.5 2.6 2.0 1.7 2.8 2.6 0.7 2.3
Worrier / anxious feelings 0.2 0.4 3.4 -0.8 -0.2 -0.3 -0.4 -0.0 -0.6 0.3 -0.3 1.6 1.9 0.0 -0.3 -0.3 -0.2 -0.8 -0.3 0.6 -0.3 0.6 -0.8 -0.7 0.0 -0.3 -0.2 -0.3 1.3 -0.1 -0.3 -0.5 -0.3 0.1 0.6 0.2 -0.2 0.3 -0.5 1.0 -0.4 1.4 -0.5 -0.6 1.1 -0.5 0.7 0.7 0.3 -0.8 -1.0 -0.2
Frequency of tiredness / lethargy in last 2 weeks 1.0 1.6 4.2 -1.1 -1.4 -1.4 -1.4 -1.3 -1.4 -0.8 -1.5 -1.0 0.2 0.0 -1.4 -1.4 -1.4 -1.8 -1.4 -1.0 -1.4 -0.8 -1.7 -2.0 -1.1 -1.5 -1.4 -1.4 -0.1 -1.4 -1.4 -0.8 -1.5 1.5 -0.9 -1.2 -1.4 -0.6 -1.6 -0.4 -1.6 -0.2 -1.4 -1.4 -0.2 -1.5 -0.9 -0.7 -1.0 -1.7 -1.5 -1.7
Falls in the last year 1.6 2.1 5.1 -1.5 -1.8 -1.8 -1.7 -1.1 -1.4 -1.4 -1.3 -1.7 -0.1 0.0 -1.8 -1.8 -1.7 -1.9 -1.7 -1.2 -1.8 -0.7 -1.8 -2.2 -1.8 -1.4 -1.5 -1.8 -0.6 -1.5 -1.8 -0.5 -1.8 1.9 -0.7 -1.5 -1.5 -0.9 -1.8 -0.7 -1.4 -0.2 -1.4 -1.3 -0.6 -1.6 -1.0 -0.9 -1.2 -1.7 -1.5 -1.4
Hair/balding pattern: Pattern 3 0.3 0.5 3.1 -0.4 -0.5 -0.5 -0.5 -0.5 -0.6 -0.8 -0.6 -1.6 -1.8 0.0 -0.5 -0.5 -0.7 -0.5 -0.6 -1.0 -0.5 -1.0 -0.3 -0.6 -0.9 -0.6 -0.7 -0.5 -1.0 -0.6 -0.5 -0.8 -0.4 0.5 -0.7 -0.3 -0.7 -0.3 -0.1 0.1 -0.4 -0.5 -0.2 -0.3 -0.6 -0.3 -0.7 -0.9 -0.8 -0.3 1.1 -0.6
Number of live births 0.1 0.1 1.4 -0.3 -0.2 -0.3 -0.2 0.3 0.1 -0.3 -0.1 1.2 1.0 0.0 -0.2 -0.3 -0.2 -0.2 -0.2 0.4 -0.3 0.1 -0.3 -0.2 0.2 -0.1 -0.1 -0.3 -0.0 -0.1 -0.2 0.7 -0.2 0.3 -0.0 -0.2 -0.1 -0.3 -0.4 -0.4 -0.3 -0.1 -0.3 -0.3 -0.1 -0.4 0.0 0.0 -0.1 -0.3 -0.6 -0.1
Forced expiratory volume in 1-second (FEV1) 0.5 1.6 19.4 1.4 -0.1 -0.0 -0.1 -0.6 -0.7 -1.2 -0.4 -3.3 -3.3 0.0 -0.0 0.0 -0.1 -0.6 -0.1 -1.3 -0.0 -1.6 0.6 0.8 -0.5 -0.2 -0.3 0.0 -3.1 -0.2 0.0 0.1 0.3 0.7 -0.9 0.1 -0.4 0.5 1.1 0.1 0.5 -0.5 1.4 0.9 -0.9 0.2 -1.9 -1.0 -2.0 0.2 4.4 -0.4
Pulse rate 0.3 0.5 1.8 -0.1 0.8 0.7 0.8 0.2 0.7 0.8 0.5 0.7 0.8 0.0 0.8 0.7 0.6 0.9 0.6 0.7 0.7 0.5 0.7 0.5 0.8 0.5 0.5 0.7 1.2 0.6 0.7 1.0 0.7 -1.2 0.5 1.1 0.5 0.4 0.7 1.0 0.4 0.8 0.2 0.2 0.6 0.6 1.3 0.4 1.0 0.5 0.5 0.8
Happiness 0.8 1.0 3.3 1.1 0.9 1.0 1.0 1.0 0.8 0.8 1.1 0.5 0.6 0.0 1.0 0.9 1.1 1.3 1.0 1.1 0.9 1.0 1.1 0.9 0.9 1.1 1.1 1.0 0.2 1.1 1.0 1.8 1.0 -0.6 1.1 0.8 1.1 1.3 1.0 0.7 1.3 0.8 1.5 1.4 0.9 0.9 0.2 1.1 0.7 1.0 0.9 0.8
Noisy workplace 0.1 0.1 0.4 -0.1 -0.2 -0.2 -0.2 0.1 -0.2 0.1 0.2 -0.3 0.3 0.0 -0.3 -0.3 -0.0 0.0 -0.1 -0.1 -0.2 0.5 -0.6 -0.3 -0.0 0.1 -0.0 -0.3 0.1 -0.1 -0.2 -0.2 -0.2 0.3 0.3 -0.2 -0.1 0.5 -0.3 -0.0 0.0 0.5 0.2 0.2 0.6 -0.3 -0.4 0.5 -0.3 -0.5 -0.3 -0.1
Qualifications: A levels/AS levels or equivalent 0.2 0.4 5.2 0.5 -0.2 -0.2 -0.1 0.5 0.4 -0.3 0.4 0.1 -0.7 0.0 -0.1 -0.2 0.2 1.3 0.0 -0.7 -0.2 0.3 0.0 0.3 -0.2 0.4 0.3 -0.2 -0.8 0.0 -0.1 -0.8 -0.2 0.6 0.0 -0.4 0.3 0.4 -0.4 -2.3 -0.4 -1.5 0.1 0.5 -0.2 -0.1 -1.2 0.3 -0.4 -0.4 -0.9 -0.3
Serious illness, injury or assault of a close relative in last 2 years 1.3 1.5 5.7 1.1 1.2 1.3 1.3 1.5 1.0 1.3 1.2 1.2 1.0 0.0 1.4 1.3 1.3 1.2 1.3 1.4 1.3 1.1 1.4 1.3 1.4 1.3 1.4 1.3 0.4 1.4 1.3 2.4 1.3 -1.1 1.2 1.2 1.5 0.8 1.3 0.5 1.3 0.4 1.4 1.3 0.6 1.4 0.9 1.0 1.1 1.4 1.0 1.4
Mouth/teeth dental problems: Dentures 0.9 1.4 7.6 -1.5 -0.9 -1.0 -0.7 -1.6 -1.5 -1.1 -1.1 -2.5 -1.6 0.0 -1.0 -0.9 -1.1 -2.8 -1.1 -0.9 -0.9 -1.4 -1.1 -1.8 -1.2 -1.2 -1.5 -0.9 -0.6 -1.4 -1.0 -0.6 -0.9 0.3 -1.8 -0.7 -1.8 -1.0 -0.6 0.1 -0.7 0.4 -0.9 -1.3 -1.0 -1.1 -0.7 -1.4 -1.4 -1.0 0.9 -0.7
Asthma 0.2 0.3 2.7 0.7 -0.2 -0.1 0.2 0.3 -0.0 0.2 0.5 -1.0 0.8 0.0 -0.1 -0.2 0.2 0.6 0.1 -0.3 -0.2 1.1 -0.1 -0.5 -0.0 0.5 0.4 -0.2 0.3 0.3 -0.1 -0.3 -0.1 0.4 1.1 0.3 0.3 1.6 -0.1 0.3 0.2 0.9 0.7 0.9 1.3 0.0 -0.3 1.1 -0.1 -0.5 0.1 -0.3
Medication: Ibuprofen (e.g. Nurofen) 1.2 1.5 5.0 -0.4 -1.5 -1.4 -1.4 -1.5 -0.2 -1.2 -0.9 -2.2 -0.0 0.0 -1.6 -1.5 -1.2 -0.9 -1.3 -1.1 -1.5 -0.1 -1.8 -2.2 -1.6 -1.1 -1.1 -1.5 -0.4 -1.2 -1.5 -1.3 -1.5 1.3 -0.1 -0.9 -1.1 0.1 -1.4 -0.4 -1.4 0.7 -0.9 -1.0 0.5 -1.7 -1.0 0.1 -1.5 -2.1 -0.8 -1.4
Medication: Cholesterol lowering 0.1 0.2 0.8 -0.7 -0.4 -0.4 -0.3 0.1 -0.0 -0.0 -0.3 0.8 0.9 0.0 -0.4 -0.4 -0.3 -0.3 -0.3 0.2 -0.4 0.1 -0.3 -0.5 -0.0 -0.3 -0.3 -0.4 0.1 -0.3 -0.4 0.1 -0.4 -0.0 -0.2 -0.3 -0.3 -0.8 -0.5 -0.9 -0.5 -0.3 -0.6 -0.5 -0.6 -0.4 0.2 -0.3 -0.1 -0.3 -0.9 -0.1
Depression (self-reported) 0.0 0.1 1.0 0.2 0.1 0.0 0.2 0.1 -0.1 -0.1 -0.1 0.3 -0.0 0.0 0.2 0.1 -0.0 -0.2 0.0 0.1 0.1 -0.3 0.1 0.4 0.3 0.0 -0.1 0.2 -0.2 0.0 0.1 0.2 0.2 0.1 -0.2 0.3 -0.1 0.1 0.3 0.5 0.0 0.3 0.1 -0.0 0.1 0.0 0.0 -0.1 -0.2 -0.0 1.0 0.1
Medication: Lansoprazole 0.4 0.5 1.4 -0.9 -0.4 -0.5 -0.5 -1.1 -0.9 -0.5 -0.7 -1.1 -0.9 0.0 -0.4 -0.4 -0.6 -0.8 -0.6 -0.8 -0.4 -0.9 -0.7 -0.9 -0.5 -0.8 -0.8 -0.4 -0.1 -0.8 -0.5 -1.1 -0.5 0.0 -1.2 -0.5 -1.0 -0.7 -0.4 -0.1 -0.7 -0.3 -0.8 -0.9 -0.6 -0.6 -0.5 -0.8 -0.5 -0.6 -0.1 -0.6
Prospective memory result 0.6 0.7 4.1 0.3 0.5 0.5 0.6 0.1 -0.3 0.8 0.7 -0.7 0.9 0.0 0.5 0.5 0.5 -0.3 0.5 0.7 0.5 1.0 0.3 0.1 0.3 0.7 0.5 0.5 1.0 0.7 0.5 1.7 0.6 -0.2 1.3 1.2 0.5 1.5 0.7 2.0 0.7 2.0 0.9 0.7 1.6 0.4 0.9 1.1 0.5 0.1 1.3 0.6
Lung cancer (father) 0.3 0.3 2.1 1.4 0.1 0.2 0.5 0.7 -0.7 -0.1 0.5 -0.9 -0.3 0.0 0.2 0.2 0.4 -0.3 0.3 -0.1 0.2 0.3 0.8 0.6 0.2 0.6 0.5 0.2 -1.1 0.5 0.2 1.1 0.3 0.0 0.5 0.1 0.6 0.4 0.4 -0.8 0.6 -0.6 1.0 1.1 -0.4 0.6 -0.6 0.1 -0.3 0.6 1.1 0.2
Illnesses of mother 0.4 0.5 3.8 1.8 0.2 0.3 0.3 0.8 -0.3 -0.2 0.4 -0.6 -1.5 0.0 0.3 0.3 0.3 0.4 0.3 -0.6 0.3 -0.3 0.5 0.8 0.1 0.5 0.4 0.3 -1.6 0.4 0.3 -0.4 0.4 0.2 0.2 0.2 0.4 0.8 0.7 -0.4 0.5 -0.6 1.0 1.0 0.1 0.4 -1.0 0.1 -0.8 0.2 2.0 0.0
Forced expiratory volume in 1-second (FEV1), Best measure 0.4 1.3 17.8 1.5 0.2 0.3 0.4 -0.5 -0.5 -0.8 -0.1 -2.9 -3.0 0.0 0.3 0.3 0.2 -0.3 0.2 -1.0 0.3 -1.2 0.8 1.1 -0.1 0.1 0.1 0.4 -2.7 0.2 0.3 0.5 0.6 0.3 -0.6 0.4 -0.0 0.7 1.3 -0.0 0.7 -0.4 1.5 1.1 -0.5 0.4 -1.6 -0.6 -1.7 0.3 4.2 -0.2
Pulse wave Arterial Stiffness index 0.1 0.2 0.9 -0.8 -0.2 -0.2 -0.5 -0.8 -0.1 -0.2 -0.4 -1.0 -0.2 0.0 -0.3 -0.2 -0.4 -0.5 -0.3 -0.2 -0.2 -0.3 -0.4 -0.7 -0.4 -0.4 -0.4 -0.3 0.2 -0.4 -0.3 -0.9 -0.3 0.2 -0.2 -0.0 -0.4 -0.1 -0.2 0.7 -0.3 0.5 -0.4 -0.5 0.1 -0.4 0.2 -0.3 -0.1 -0.4 0.1 -0.1
Impedance of arm (left) 0.4 1.9 7.0 -2.3 -0.9 -1.0 -1.2 -1.3 -0.2 -1.3 -1.6 -0.7 -1.8 0.0 -1.0 -0.9 -1.5 -0.7 -1.3 -0.9 -0.9 -2.5 -1.0 -0.7 -1.0 -1.6 -1.9 -0.9 -0.6 -1.7 -1.0 -2.1 -1.0 0.8 -2.6 -1.1 -2.1 -2.2 -0.8 0.1 -1.0 -0.5 -1.7 -2.0 -2.0 -1.2 -0.4 -2.4 -1.0 -0.6 0.1 -0.8
Arm fat mass (right) 0.3 1.2 3.4 1.2 1.0 1.1 1.3 1.8 0.1 1.0 1.0 1.7 1.4 0.0 1.1 1.0 1.1 0.8 1.1 1.2 1.0 1.3 1.2 0.8 1.2 1.0 1.3 1.0 1.0 1.3 1.0 1.8 1.0 -1.4 1.2 0.7 1.4 0.4 0.7 -0.0 0.9 -0.1 0.7 1.0 0.5 1.2 1.2 1.0 1.4 1.3 -0.7 1.1
Trunk predicted mass 0.4 2.0 4.7 1.9 1.4 1.5 1.4 1.1 0.7 1.5 1.3 0.7 0.9 0.0 1.4 1.5 1.5 0.5 1.5 1.3 1.5 1.3 1.7 1.9 1.5 1.4 1.5 1.5 0.4 1.6 1.5 1.4 1.6 -1.6 1.6 1.7 1.6 1.4 1.7 1.3 1.7 1.2 1.8 1.7 1.0 1.5 1.2 1.2 0.9 1.5 2.2 1.4
Standing height 0.2 1.5 20.1 -0.1 1.1 1.1 0.7 -0.0 -0.0 0.8 0.1 -0.0 -1.5 0.0 1.1 1.2 0.7 -0.7 0.9 0.7 1.2 -1.0 1.5 2.2 0.9 0.4 0.0 1.2 -0.6 0.5 1.2 -0.1 1.4 -1.2 -0.8 1.5 -0.1 -0.2 2.1 2.4 1.6 1.3 1.2 0.5 -0.8 1.0 1.1 -0.9 -0.1 1.6 4.5 1.2
Length of working week for main job 1.3 1.4 3.8 -1.6 -1.0 -1.0 -1.1 -1.5 -0.7 -0.7 -1.6 -1.4 -0.8 0.0 -1.0 -1.0 -1.4 -0.9 -1.3 -0.9 -1.0 -1.6 -1.3 -1.3 -1.0 -1.6 -1.5 -1.0 0.1 -1.5 -1.0 -1.6 -1.1 0.3 -1.7 -0.9 -1.6 -1.7 -1.0 -0.0 -1.4 -0.5 -1.9 -2.0 -1.1 -1.1 0.0 -1.5 -0.6 -1.0 -0.8 -0.9
Exposure to tobacco smoke at home 2.8 3.1 6.4 -1.7 -2.0 -2.0 -1.8 -2.1 -2.5 -1.7 -1.7 -2.3 -1.7 0.0 -2.1 -2.0 -1.8 -2.4 -1.9 -2.1 -2.0 -1.2 -1.6 -2.0 -2.3 -1.8 -1.9 -2.0 -1.3 -1.9 -2.0 -2.1 -1.9 1.6 -1.3 -1.6 -1.9 -1.2 -1.7 -1.2 -1.6 -0.8 -1.4 -1.3 -1.5 -1.8 -1.5 -1.5 -1.8 -1.8 -0.5 -1.8
Breastfed as a baby 0.1 0.1 1.3 0.4 0.4 0.4 0.4 0.0 0.2 0.1 0.1 -0.4 -0.9 0.0 0.4 0.4 0.2 0.2 0.3 -0.2 0.4 -0.4 0.6 0.4 0.1 0.1 0.3 0.4 -0.1 0.2 0.4 -0.4 0.4 -0.5 -0.1 0.2 0.4 -0.4 0.3 -0.5 -0.0 -1.1 -0.1 0.0 -0.4 0.4 0.2 -0.3 0.5 0.5 -0.2 0.2
Tense / ‘highly strung’ 2.0 3.3 7.1 -2.2 -2.2 -2.2 -2.2 -2.6 -1.9 -1.3 -2.1 -1.5 0.7 0.0 -2.2 -2.3 -2.0 -2.5 -2.1 -1.4 -2.3 -0.8 -2.5 -2.1 -1.7 -2.0 -2.0 -2.3 -0.6 -1.9 -2.2 -0.8 -2.2 2.3 -0.6 -1.4 -2.1 -0.6 -2.0 0.3 -1.9 1.1 -1.5 -1.8 -0.2 -2.5 -1.1 -0.8 -2.1 -2.7 -0.5 -2.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.5 0.7 11.8 -0.1 -0.0 -0.1 -0.1 -0.7 -0.3 -0.5 -0.4 -1.6 -1.0 0.0 -0.1 -0.0 -0.2 -1.2 -0.2 -0.3 -0.0 -0.9 -0.3 -0.4 -0.4 -0.4 -0.6 -0.0 -0.5 -0.4 -0.0 -0.4 0.2 0.3 -0.5 0.9 -0.9 0.7 0.8 2.1 0.2 1.9 0.5 -0.1 0.6 -0.2 -0.0 -0.3 -1.1 -0.6 3.4 -0.1
Hair/balding pattern: Pattern 4 0.2 0.6 3.3 0.6 0.4 0.4 0.5 -0.1 0.2 0.9 0.7 0.4 1.4 0.0 0.4 0.4 0.5 -0.3 0.5 0.6 0.3 1.2 0.0 -0.3 0.4 0.7 0.6 0.4 0.9 0.6 0.4 0.4 0.4 -0.3 1.2 1.2 0.5 1.5 0.5 1.1 0.2 1.6 0.6 0.4 1.8 0.1 0.7 1.4 0.2 -0.4 0.8 0.5
Birth weight of first child 0.3 0.5 2.9 0.0 -0.5 -0.4 -0.6 -0.8 -0.6 -1.4 -0.6 -0.3 -1.4 0.0 -0.4 -0.4 -0.5 -0.0 -0.4 -1.3 -0.4 -1.0 -0.3 -0.0 -0.4 -0.6 -0.3 -0.4 -1.5 -0.5 -0.4 -0.4 -0.4 0.9 -0.6 -0.7 -0.2 -0.4 -0.3 -1.5 -0.7 -1.7 -0.3 -0.1 -0.8 -0.3 -1.3 -0.6 -0.9 -0.4 0.0 -0.8
Peak expiratory flow (PEF) 0.1 0.2 1.3 1.1 0.6 0.6 0.6 -0.1 0.5 0.2 0.2 -0.3 -0.4 0.0 0.6 0.6 0.5 0.8 0.6 0.0 0.6 0.1 0.7 0.8 0.5 0.2 0.5 0.6 0.1 0.4 0.6 0.3 0.6 -0.7 0.0 0.5 0.4 0.1 0.6 -0.1 0.3 -0.2 0.3 0.4 -0.1 0.6 0.4 0.1 0.3 0.6 0.6 0.4
Pulse wave reflection index 0.2 0.3 2.0 -0.3 -0.4 -0.5 -0.8 -0.8 -0.3 -0.4 -0.6 -1.4 -0.2 0.0 -0.5 -0.5 -0.6 -0.8 -0.6 -0.6 -0.5 -0.5 -0.5 -0.7 -0.6 -0.5 -0.5 -0.5 -0.1 -0.5 -0.5 -1.1 -0.4 0.6 -0.0 -0.2 -0.4 -0.1 -0.3 0.9 -0.3 0.4 -0.3 -0.4 0.1 -0.4 -0.1 -0.3 -0.3 -0.4 0.3 -0.4
Ever highly irritable/argumentative for 2 days 0.8 0.9 2.8 -1.1 -1.2 -1.2 -1.2 -0.6 -0.6 -0.9 -0.5 -0.2 0.1 0.0 -1.3 -1.2 -1.0 -1.4 -1.1 -0.6 -1.2 -0.2 -1.5 -1.7 -1.4 -0.6 -1.0 -1.2 -0.4 -0.9 -1.2 -0.6 -1.1 1.6 -0.2 -0.7 -1.0 0.2 -1.0 0.3 -0.6 1.0 -0.4 -0.6 0.4 -1.5 -0.9 -0.1 -1.1 -1.5 -0.2 -0.7
Loud music exposure frequency 0.4 0.5 1.7 0.5 -0.7 -0.6 -0.5 -1.0 -1.3 -0.5 -0.4 -0.5 -0.2 0.0 -0.6 -0.6 -0.4 -0.7 -0.4 -1.0 -0.6 0.1 -0.3 -0.7 -0.6 -0.3 -0.1 -0.6 -1.3 -0.2 -0.6 -0.4 -0.5 1.0 0.6 -0.0 -0.0 1.1 -0.2 -0.2 -0.5 0.0 0.6 0.5 0.6 -0.5 -1.3 0.4 -1.2 -1.0 1.3 -1.1
Qualifications: O levels/GCSEs or equivalent 0.6 1.0 3.3 -0.7 -1.1 -1.1 -1.0 -1.8 -1.1 -1.2 -0.8 -0.5 -0.5 0.0 -1.1 -1.2 -0.9 -0.6 -1.0 -1.3 -1.1 -0.3 -1.0 -1.1 -1.1 -0.9 -0.8 -1.2 -0.6 -1.0 -1.1 -1.1 -1.2 1.1 -0.6 -1.0 -0.9 -0.4 -1.3 -1.6 -1.2 -0.9 -0.8 -0.6 -0.7 -1.1 -1.3 -0.5 -0.9 -1.3 -1.2 -1.3
Mouth/teeth dental problems: Bleeding gums 0.0 0.1 0.6 -0.3 0.1 0.2 0.0 -0.3 -0.2 0.7 0.1 0.4 -0.1 0.0 0.1 0.1 0.2 -0.1 0.2 -0.1 0.1 0.1 -0.2 0.3 0.1 0.1 -0.0 0.1 0.0 0.0 0.1 -0.6 0.1 -0.1 -0.1 0.2 -0.1 0.3 0.2 -0.0 0.1 0.4 0.0 -0.0 0.4 -0.1 0.1 0.2 -0.1 -0.2 0.3 0.2
Blood clot in the leg (DVT) 0.5 0.6 1.7 0.5 0.9 0.9 1.0 0.9 1.3 1.0 0.5 0.8 -0.1 0.0 1.0 0.9 0.7 1.1 0.8 0.4 1.0 0.1 1.1 0.8 0.9 0.7 0.8 1.0 0.3 0.7 0.9 0.8 0.9 -1.1 -0.0 0.4 0.8 -0.1 0.7 -0.6 0.6 -1.2 0.3 0.6 -0.3 1.1 0.5 -0.0 1.2 1.3 -0.4 0.7
Medication: Paracetamol 1.1 1.8 4.6 -0.8 -1.6 -1.6 -1.5 -1.2 -1.4 -1.7 -0.9 -2.0 -0.2 0.0 -1.7 -1.7 -1.2 -1.7 -1.4 -1.2 -1.7 -0.1 -1.7 -2.1 -1.8 -1.1 -1.2 -1.7 -0.6 -1.3 -1.6 -1.6 -1.6 1.5 -0.3 -1.2 -1.3 -0.0 -1.6 -0.6 -1.2 0.5 -0.7 -0.8 0.0 -1.7 -1.4 -0.2 -1.6 -2.0 -0.8 -1.4
Headache pain in last month 4.3 7.4 18.2 -4.3 -2.8 -2.9 -3.1 -3.2 -1.6 -1.7 -2.9 -1.0 0.4 0.0 -2.9 -2.9 -3.1 -2.8 -3.1 -1.8 -2.9 -1.8 -3.9 -3.9 -2.7 -3.0 -3.2 -2.9 0.8 -3.1 -2.9 -3.1 -3.1 2.3 -2.0 -2.3 -3.2 -2.4 -3.3 0.2 -3.2 0.5 -3.8 -4.0 -0.6 -3.3 -0.5 -1.7 -1.6 -3.5 -3.6 -2.4
Medication for cholesterol, blood pressure or diabetes 0.2 0.4 3.5 0.8 0.3 0.3 0.1 0.4 -0.6 -0.5 0.1 -1.1 -1.9 0.0 0.3 0.3 0.1 0.1 0.2 -0.5 0.3 -1.0 0.5 1.0 0.1 0.1 -0.0 0.3 -1.4 0.1 0.3 0.3 0.4 0.3 -0.6 0.0 0.0 0.2 0.7 0.0 0.5 -0.8 0.7 0.5 -0.4 0.4 -0.9 -0.6 -0.6 0.5 1.8 0.0
Glaucoma (self-reported) 0.9 1.0 3.5 1.1 0.9 1.0 0.9 1.9 1.8 0.8 1.2 1.1 1.0 0.0 0.9 1.0 1.0 1.4 1.0 1.2 0.9 1.2 1.1 1.1 1.0 1.1 1.2 0.9 0.9 1.1 0.9 0.4 0.9 -1.0 1.2 0.5 1.3 0.5 0.6 0.3 1.0 0.1 0.8 1.0 0.4 1.0 0.8 0.8 1.4 1.3 -0.7 1.0
Gout (self-reported) 0.3 0.4 1.0 0.8 0.7 0.7 0.8 0.3 -0.1 0.8 0.7 -0.7 -0.0 0.0 0.7 0.7 0.8 0.0 0.8 0.6 0.7 0.6 0.7 0.4 0.7 0.8 0.7 0.7 0.1 0.7 0.8 0.4 0.8 -0.9 0.5 0.7 0.7 0.7 0.9 0.2 0.8 0.3 1.0 0.9 0.5 0.9 0.2 0.6 0.4 0.7 1.0 0.7
Hypothyroidism/myxoedema (self-reported) 0.2 0.5 2.2 -0.4 0.6 0.6 0.6 -0.3 0.6 1.1 0.5 -0.3 0.3 0.0 0.5 0.6 0.6 -0.5 0.5 0.4 0.6 0.8 0.2 -0.4 0.1 0.5 0.5 0.6 1.2 0.5 0.6 -0.4 0.6 -0.8 0.6 0.9 0.4 1.2 0.6 1.5 0.6 1.5 0.5 0.4 1.5 0.4 0.9 1.0 0.6 0.1 0.5 0.5
Medication: Amlodipine 0.8 1.1 4.3 1.3 0.7 0.7 0.9 0.9 0.3 1.3 1.1 0.8 1.9 0.0 0.6 0.6 1.0 0.4 0.8 0.9 0.6 1.9 0.8 0.5 0.8 1.2 1.2 0.6 1.2 1.2 0.7 1.4 0.7 -0.7 2.1 1.1 1.3 1.8 0.6 1.3 0.9 1.4 1.2 1.3 1.6 0.7 0.8 1.7 1.0 0.4 0.2 0.6
Medication: Ventolin 100micrograms inhaler 0.6 0.8 4.3 -0.5 -1.0 -1.1 -0.8 -0.8 -0.8 -0.7 -0.6 0.7 0.2 0.0 -1.0 -1.1 -0.8 -0.1 -0.9 -1.1 -1.1 0.1 -1.1 -0.9 -0.9 -0.6 -0.6 -1.1 -0.1 -0.8 -1.0 -0.7 -1.1 1.6 -0.2 -1.1 -0.5 -0.2 -1.4 -1.4 -1.1 -0.8 -1.0 -0.6 -0.1 -1.0 -0.8 -0.1 -0.6 -1.2 -2.1 -1.1
Birth weight 0.3 0.6 4.0 0.8 0.4 0.5 0.3 1.0 -0.3 -0.4 0.3 0.0 -1.3 0.0 0.5 0.5 0.3 1.0 0.4 -0.1 0.5 -0.9 1.1 1.2 0.6 0.4 0.3 0.5 -1.5 0.3 0.5 -0.3 0.5 -0.5 -0.7 -0.1 0.4 -0.3 0.6 -1.3 0.6 -2.0 0.6 0.8 -1.3 0.7 -0.7 -0.8 0.0 1.1 0.9 0.2
Chronic bronchitis/emphysema (mother) 0.2 0.2 1.6 -0.5 -0.5 -0.6 -0.3 -0.6 -0.3 -0.3 -0.4 0.2 0.6 0.0 -0.5 -0.6 -0.4 -0.8 -0.5 -0.1 -0.5 0.0 -0.5 -0.7 -0.4 -0.4 -0.5 -0.6 -0.1 -0.5 -0.5 1.3 -0.5 0.6 -0.2 -0.3 -0.6 -0.1 -0.4 0.2 -0.3 0.8 -0.2 -0.4 -0.1 -0.8 -0.3 -0.2 -0.7 -0.7 0.1 -0.4
High blood pressure (siblings) 0.9 1.3 4.3 1.2 0.7 0.7 1.0 1.3 1.8 1.1 1.3 1.9 2.0 0.0 0.7 0.7 1.1 1.3 0.9 1.0 0.7 2.1 0.7 0.3 0.7 1.2 1.4 0.7 1.7 1.2 0.7 0.6 0.6 -0.6 2.0 0.8 1.4 1.5 0.2 0.4 0.7 0.8 0.7 1.1 1.7 0.8 1.0 1.9 1.4 0.5 -1.3 0.7
Forced vital capacity (FVC), Best measure 0.6 2.3 35.1 1.8 0.5 0.6 0.7 -0.2 -1.0 -0.6 0.2 -3.6 -3.7 0.0 0.6 0.6 0.5 -0.4 0.5 -1.0 0.6 -1.3 1.2 1.4 -0.1 0.4 0.2 0.7 -3.2 0.4 0.7 0.3 1.0 0.2 -0.6 0.9 0.1 1.4 2.0 0.8 1.3 0.2 2.3 1.7 -0.2 0.8 -1.6 -0.5 -1.9 0.7 5.9 0.1
Body fat percentage 0.1 0.4 2.6 0.1 0.6 0.6 0.7 1.0 -0.3 0.5 0.4 1.6 0.7 0.0 0.6 0.6 0.5 0.4 0.5 0.7 0.6 0.5 0.6 0.1 0.6 0.4 0.6 0.6 0.8 0.6 0.5 1.4 0.5 -0.9 0.3 -0.0 0.7 -0.5 0.1 -0.4 0.4 -0.6 -0.1 0.1 -0.3 0.6 0.9 0.1 1.2 1.0 -1.4 0.6
Leg fat percentage (right) 0.2 0.6 4.4 0.4 0.6 0.6 0.7 1.1 -0.1 0.7 0.6 2.1 1.0 0.0 0.6 0.6 0.6 0.8 0.6 0.7 0.6 0.9 0.7 0.3 0.6 0.6 0.9 0.6 0.7 0.7 0.6 1.4 0.5 -0.7 0.7 -0.2 1.1 -0.3 -0.0 -0.8 0.4 -1.0 -0.0 0.4 -0.1 0.6 0.7 0.4 1.3 1.0 -2.0 0.6
Arm fat-free mass (right) 0.2 1.2 1.9 1.3 1.1 1.2 1.1 0.7 0.2 1.2 0.9 0.8 0.6 0.0 1.2 1.1 1.2 0.1 1.2 0.9 1.1 1.1 1.3 1.3 1.0 1.1 1.2 1.1 0.4 1.3 1.2 1.2 1.2 -1.2 1.3 1.2 1.3 1.0 1.3 1.1 1.3 0.8 1.3 1.3 0.8 1.2 1.1 1.0 0.9 1.2 1.4 1.0
Exposure to tobacco smoke outside home 0.2 0.2 1.0 0.4 -0.5 -0.5 -0.4 -0.0 -0.9 -0.2 0.1 -0.9 0.1 0.0 -0.5 -0.5 -0.2 -0.7 -0.3 -0.7 -0.5 0.5 -0.3 -0.7 -0.6 0.1 -0.1 -0.5 -0.3 -0.1 -0.5 0.3 -0.4 1.0 0.6 -0.2 -0.1 0.9 -0.4 -0.1 -0.2 0.3 0.3 0.4 0.5 -0.4 -0.7 0.4 -0.6 -0.7 0.2 -0.5
Comparative body size at age 10 0.5 1.4 3.3 1.0 1.1 1.1 1.1 1.4 1.7 1.4 1.3 1.6 1.6 0.0 1.1 1.1 1.1 1.8 1.1 1.4 1.1 1.5 1.0 0.4 1.1 1.3 1.3 1.1 1.5 1.2 1.1 0.6 1.0 -1.4 1.3 0.5 1.4 0.5 0.6 0.8 1.2 0.7 0.8 0.9 0.9 1.1 1.3 1.1 1.7 1.4 -1.1 1.4
Number of full brothers 0.2 0.2 1.4 -0.3 -0.1 -0.2 -0.2 0.3 0.9 0.0 0.0 -0.5 0.7 0.0 -0.2 -0.2 -0.1 0.2 -0.1 0.5 -0.2 0.4 -0.5 -0.8 -0.2 -0.1 -0.2 -0.1 1.2 -0.2 -0.1 -0.2 -0.2 0.1 0.0 -0.1 -0.3 0.1 -0.3 0.9 0.1 1.1 -0.4 -0.4 0.6 -0.2 0.6 0.3 0.4 -0.2 -0.9 0.1
Worry too long after embarrassment 0.1 0.2 1.7 0.3 0.2 0.2 0.2 0.0 0.2 0.4 0.0 0.6 1.0 0.0 0.2 0.2 0.2 -0.2 0.2 0.4 0.2 0.6 0.1 -0.2 0.3 0.2 0.3 0.2 0.6 0.3 0.2 -0.4 0.2 -0.3 0.8 0.5 0.3 0.6 0.3 1.3 0.3 1.3 0.4 0.2 0.8 0.1 0.6 0.6 0.2 0.0 0.5 0.0
Seen a psychiatrist for nerves, anxiety, tension or depression 0.5 0.6 6.7 0.4 0.4 0.5 0.5 0.6 0.8 0.5 0.3 0.3 0.3 0.0 0.5 0.5 0.5 0.2 0.5 0.5 0.5 0.3 0.3 0.4 0.3 0.4 0.3 0.4 0.2 0.5 0.5 1.3 0.6 -0.0 0.5 1.2 0.0 1.4 1.0 1.8 0.7 2.0 1.1 0.6 1.2 0.2 0.3 0.7 -0.2 -0.1 2.6 0.4
Wheeze or whistling in the chest in last year 1.9 3.4 7.0 -1.4 -2.3 -2.3 -2.1 -1.8 -2.6 -2.0 -1.6 -1.5 -0.2 0.0 -2.2 -2.3 -1.9 -2.3 -2.0 -2.1 -2.3 -0.6 -2.3 -2.4 -2.0 -1.7 -1.6 -2.3 -1.1 -1.8 -2.3 -0.8 -2.3 2.6 -0.7 -2.0 -1.7 -0.5 -2.4 -1.6 -1.9 -0.6 -1.4 -1.2 -0.5 -2.2 -2.0 -0.7 -1.9 -2.4 -1.9 -2.2
Number of children fathered 0.5 0.5 3.2 0.3 0.7 0.7 0.7 0.1 1.4 0.7 0.7 1.8 0.8 0.0 0.7 0.7 0.7 0.9 0.7 0.7 0.7 0.7 0.7 0.9 0.9 0.6 0.8 0.7 0.6 0.6 0.7 0.8 0.5 -0.9 0.4 0.1 0.8 -0.4 0.2 -0.8 0.6 -0.5 0.2 0.4 -0.3 0.6 0.7 0.3 1.0 1.0 -1.2 0.7
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 5.7 1.3 0.8 0.8 1.0 0.9 -0.2 0.3 0.6 -0.7 -0.3 0.0 0.9 0.8 0.9 1.5 0.9 0.7 0.9 0.3 1.4 1.4 0.8 0.8 0.9 0.9 -0.7 0.9 0.9 1.6 1.0 -0.9 0.6 1.0 0.8 0.7 1.3 0.3 1.0 0.3 1.4 1.3 -0.1 1.0 0.1 0.3 0.0 1.0 2.4 0.7
Age at first live birth 1.4 2.5 5.7 -1.7 -1.3 -1.4 -1.6 -1.7 -0.8 -1.4 -1.9 -1.2 -1.4 0.0 -1.4 -1.4 -1.7 -0.8 -1.6 -1.9 -1.4 -1.8 -1.5 -1.1 -1.5 -1.8 -1.6 -1.4 -0.6 -1.7 -1.4 -2.0 -1.5 0.8 -1.8 -1.6 -1.5 -2.3 -1.7 -1.6 -2.0 -2.1 -2.3 -2.1 -1.8 -1.3 -0.7 -1.8 -0.7 -1.2 -2.4 -1.5
Pulse wave peak to peak time 0.1 0.2 1.3 0.8 0.2 0.2 0.5 0.8 -0.1 0.1 0.3 1.1 0.1 0.0 0.2 0.2 0.4 0.4 0.3 0.2 0.2 0.2 0.4 0.9 0.4 0.3 0.3 0.3 -0.4 0.3 0.3 0.9 0.3 -0.2 0.0 -0.0 0.4 -0.0 0.2 -0.8 0.3 -0.7 0.3 0.4 -0.3 0.3 -0.2 0.1 0.0 0.4 -0.1 0.1
Health satisfaction 0.8 1.0 2.2 -0.9 -1.3 -1.3 -1.1 -0.9 -1.5 -0.6 -0.8 -1.1 -0.1 0.0 -1.3 -1.3 -1.0 -1.4 -1.1 -0.9 -1.3 0.0 -1.1 -1.3 -1.3 -0.8 -0.8 -1.3 -0.6 -0.9 -1.3 -0.5 -1.3 1.2 -0.2 -1.0 -0.8 -0.4 -1.4 -1.0 -1.0 -0.4 -0.7 -0.6 -0.5 -1.2 -1.1 -0.3 -0.9 -1.3 -1.2 -1.3
Shortness of breath walking on level ground 2.4 2.9 4.5 -1.3 -2.0 -2.0 -1.9 -1.1 -2.0 -1.6 -1.6 -1.6 -0.6 0.0 -2.0 -2.0 -1.9 -2.0 -1.9 -1.6 -2.0 -1.1 -2.1 -2.1 -1.8 -1.7 -1.8 -2.0 -1.1 -1.8 -2.0 -1.1 -2.0 1.9 -1.3 -1.9 -1.8 -1.2 -2.0 -1.4 -1.8 -0.9 -1.7 -1.7 -1.1 -2.1 -1.6 -1.3 -1.7 -2.0 -1.7 -1.8
Qualifications: College or University degree 1.6 5.1 10.2 2.9 2.6 2.6 2.4 2.7 2.5 2.2 2.3 2.2 0.6 0.0 2.6 2.6 2.5 3.0 2.5 2.1 2.6 1.4 2.9 3.2 2.5 2.4 2.5 2.7 0.9 2.5 2.6 0.6 2.6 -2.6 1.6 2.0 2.7 1.2 2.4 0.5 2.4 -0.2 2.1 2.3 0.8 2.7 1.7 1.4 2.4 2.9 1.1 2.4
Eye problems/disorders: None of the above 0.7 0.8 3.2 -0.5 -0.9 -0.9 -1.0 -0.7 -1.8 -1.0 -1.1 -1.3 -0.6 0.0 -0.9 -0.9 -1.0 -0.8 -1.0 -0.7 -0.9 -1.0 -0.7 -0.3 -0.9 -1.0 -0.9 -0.9 -1.1 -0.8 -0.9 0.2 -0.8 0.9 -0.7 -0.7 -0.8 -0.9 -0.7 -0.5 -1.0 -0.8 -0.8 -0.9 -1.0 -0.9 -0.7 -1.0 -1.0 -0.8 -0.0 -1.0
Mouth/teeth dental problems: Loose teeth 2.0 2.3 10.2 0.4 1.8 1.8 1.7 1.1 0.2 1.7 1.1 0.3 0.3 0.0 1.8 1.8 1.4 0.1 1.6 1.7 1.8 0.6 1.5 1.1 1.5 1.2 1.1 1.8 1.6 1.4 1.8 0.9 1.9 -1.8 0.9 1.7 1.1 1.1 2.1 3.2 1.9 2.1 1.4 1.0 1.3 1.7 2.0 0.8 1.6 1.8 2.3 1.7
Emphysema/chronic bronchitis 1.5 1.7 4.3 -1.3 -1.3 -1.3 -1.3 -1.5 -1.6 -1.4 -1.5 -0.7 -0.8 0.0 -1.3 -1.3 -1.4 -2.1 -1.3 -1.4 -1.3 -1.2 -1.1 -1.2 -1.3 -1.5 -1.4 -1.3 -0.8 -1.4 -1.3 -0.9 -1.3 1.2 -1.3 -1.3 -1.4 -1.1 -1.4 -1.2 -1.4 -1.4 -1.4 -1.2 -1.3 -1.3 -1.2 -1.3 -0.9 -1.2 -1.2 -1.6
Medication for pain relief, constipation, heartburn 2.5 4.3 9.3 2.0 2.5 2.5 2.3 2.2 1.6 2.4 1.8 2.8 0.7 0.0 2.6 2.5 2.1 2.4 2.2 1.8 2.5 0.8 2.4 3.0 2.5 2.0 2.1 2.5 1.1 2.2 2.5 2.1 2.5 -2.3 1.2 2.1 2.2 1.0 2.4 1.3 2.1 0.1 1.6 1.7 1.1 2.6 2.1 1.2 2.3 2.7 1.3 2.4
Neck or shoulder pain in last month 6.3 9.0 13.0 -2.4 -3.3 -3.3 -3.2 -3.1 -3.3 -3.4 -3.2 -2.1 -1.9 0.0 -3.3 -3.3 -3.4 -3.6 -3.4 -3.0 -3.3 -2.8 -3.3 -3.4 -3.3 -3.2 -3.3 -3.4 -2.4 -3.3 -3.4 -2.1 -3.3 3.4 -2.7 -3.0 -3.2 -2.5 -3.1 -1.7 -3.3 -1.6 -3.0 -3.1 -2.2 -3.5 -2.6 -2.8 -3.3 -3.4 -1.5 -3.2
Medication: Blood pressure 0.3 0.6 3.6 -0.9 -0.4 -0.5 -0.4 -0.9 0.6 0.4 -0.4 0.1 1.9 0.0 -0.6 -0.5 -0.3 -0.6 -0.4 0.4 -0.5 1.0 -0.8 -1.5 -0.5 -0.3 -0.2 -0.5 1.7 -0.2 -0.5 -0.8 -0.6 -0.0 0.9 -0.0 -0.2 0.2 -0.8 1.4 -0.4 1.8 -0.5 -0.5 1.0 -0.6 0.9 0.7 0.5 -0.7 -1.4 -0.3
Angina (self-reported) 0.4 0.6 2.8 0.3 0.7 0.7 0.7 1.1 0.9 0.8 0.8 1.7 1.2 0.0 0.7 0.7 0.8 0.5 0.8 1.1 0.7 1.0 0.5 0.3 0.8 0.8 0.8 0.7 1.1 0.7 0.7 0.3 0.6 -0.7 0.6 0.6 0.7 0.5 0.3 -0.3 0.5 0.3 0.3 0.5 0.6 0.6 0.9 0.9 1.0 0.6 -0.8 0.8
Migraine (self-reported) 0.2 0.3 3.0 -1.4 0.3 0.2 0.2 0.1 0.6 0.6 -0.1 0.2 0.9 0.0 0.2 0.2 0.1 0.0 0.1 0.5 0.2 0.4 -0.2 -0.1 0.2 -0.1 -0.0 0.2 1.7 0.0 0.2 0.0 0.1 -0.4 0.1 0.5 -0.2 -0.1 0.0 1.3 -0.1 1.2 -0.6 -0.7 0.7 0.1 1.3 0.4 0.8 -0.1 -0.7 0.3
Medication: Ibuprofen 2.3 2.8 7.2 -1.4 -1.9 -1.9 -1.9 -2.2 -0.8 -1.5 -1.5 -2.6 -0.5 0.0 -2.0 -2.0 -1.7 -1.6 -1.8 -1.5 -2.0 -0.7 -2.4 -2.7 -2.0 -1.7 -1.7 -2.0 -0.6 -1.7 -1.9 -1.6 -2.0 1.7 -0.9 -1.4 -1.8 -0.6 -1.9 -0.7 -1.9 0.3 -1.6 -1.7 -0.1 -2.1 -1.3 -0.6 -1.9 -2.5 -1.1 -1.8
Medication: Allopurinol 0.2 0.3 0.7 0.3 0.6 0.5 0.6 0.5 -0.3 0.7 0.5 0.4 0.4 0.0 0.5 0.5 0.6 -0.4 0.6 0.9 0.6 0.5 0.5 0.3 0.7 0.5 0.4 0.6 0.4 0.5 0.6 0.5 0.6 -0.9 0.2 0.6 0.3 0.4 0.6 0.5 0.7 0.7 0.7 0.6 0.3 0.6 0.3 0.4 0.5 0.6 0.7 0.6
Medication: Omeprazole 1.4 1.7 2.9 -1.6 -1.4 -1.4 -1.2 -1.4 -0.6 -1.6 -1.4 -0.4 -0.5 0.0 -1.4 -1.4 -1.5 -1.7 -1.4 -1.1 -1.4 -1.3 -1.3 -1.2 -1.1 -1.5 -1.4 -1.4 -1.0 -1.4 -1.4 0.1 -1.4 1.4 -1.3 -1.4 -1.4 -1.7 -1.4 -0.9 -1.4 -0.9 -1.4 -1.5 -1.6 -1.5 -1.0 -1.5 -1.3 -1.2 -0.9 -1.3
Medication: Seretide 50 evohaler 0.6 0.7 3.1 -0.3 -1.1 -1.0 -0.9 -0.8 -0.8 -0.4 -0.5 -1.1 -0.3 0.0 -0.9 -1.0 -0.6 -1.0 -0.8 -1.0 -1.0 0.1 -1.0 -0.7 -0.8 -0.5 -0.5 -1.0 -1.0 -0.7 -1.0 -0.5 -0.9 1.8 -0.1 -0.9 -0.6 0.5 -0.9 -1.0 -0.7 -0.2 -0.1 0.0 0.1 -1.1 -1.7 0.0 -1.3 -1.3 -0.3 -1.3
Mean time to correctly identify matches 0.1 0.2 1.4 0.6 0.3 0.3 0.5 0.7 0.4 0.4 0.5 1.2 0.4 0.0 0.3 0.3 0.4 0.9 0.4 0.5 0.3 0.4 0.5 0.4 0.5 0.5 0.5 0.3 -0.4 0.5 0.3 1.0 0.4 -0.3 0.4 0.1 0.4 0.3 0.5 -0.0 0.6 0.3 0.8 0.7 -0.0 0.3 -0.1 0.2 -0.2 0.5 1.0 0.4
Heart disease (mother) 0.5 0.6 3.3 -1.8 -0.5 -0.6 -0.6 -1.0 -0.4 -0.8 -1.0 0.3 -0.7 0.0 -0.5 -0.5 -0.9 -0.7 -0.8 -0.8 -0.5 -1.3 -0.6 -0.8 -0.7 -1.0 -0.9 -0.5 0.0 -0.9 -0.5 0.0 -0.6 0.4 -1.2 -0.7 -1.0 -1.3 -0.6 -0.1 -0.9 -0.8 -1.3 -1.2 -1.0 -0.6 -0.0 -1.2 -0.1 -0.4 -0.8 -0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 3.8 0.9 0.4 0.4 0.5 0.7 0.9 0.9 0.6 1.9 1.3 0.0 0.4 0.4 0.5 1.1 0.5 0.7 0.4 0.9 0.4 0.1 0.6 0.6 0.6 0.4 0.9 0.5 0.4 -0.4 0.3 -1.0 0.6 0.3 0.7 0.2 -0.0 -0.5 0.2 -0.1 0.0 0.3 0.3 0.4 0.7 0.7 0.9 0.4 -1.2 0.5
Whole body fat mass 0.2 0.9 3.3 0.9 1.0 1.0 1.1 1.3 -0.1 0.9 0.8 1.8 0.9 0.0 1.0 1.0 1.0 0.6 1.0 1.0 1.0 0.9 1.2 0.7 1.0 0.9 1.1 1.0 0.8 1.1 1.0 1.6 1.0 -1.3 0.9 0.5 1.2 0.1 0.7 0.0 0.9 -0.2 0.6 0.8 0.1 1.1 1.1 0.6 1.3 1.4 -0.6 1.0
Leg fat mass (right) 0.4 1.4 4.2 1.2 1.2 1.2 1.3 1.5 0.2 1.2 1.2 2.0 1.4 0.0 1.2 1.2 1.2 0.8 1.3 1.3 1.2 1.4 1.3 0.8 1.2 1.2 1.5 1.2 1.0 1.4 1.2 1.9 1.1 -1.3 1.4 0.7 1.6 0.6 0.8 0.1 1.1 0.0 0.9 1.1 0.7 1.2 1.3 1.1 1.6 1.5 -0.8 1.2
Arm predicted mass (right) 0.4 1.9 3.4 1.8 1.4 1.5 1.4 1.1 0.3 1.4 1.2 0.9 0.6 0.0 1.5 1.4 1.5 0.5 1.5 1.1 1.4 1.3 1.6 1.7 1.4 1.4 1.6 1.4 0.3 1.6 1.4 1.5 1.5 -1.4 1.5 1.5 1.6 1.4 1.7 1.1 1.6 0.9 1.8 1.7 1.0 1.5 1.0 1.3 0.9 1.5 1.8 1.3
Pulse rate, automated reading 0.4 1.4 5.6 0.1 1.2 1.1 1.1 0.8 0.5 1.4 0.6 2.4 2.0 0.0 1.2 1.1 0.9 1.3 1.0 1.2 1.2 0.9 1.0 1.3 1.6 0.8 1.1 1.2 1.9 1.1 1.1 1.9 1.1 -1.5 1.1 1.1 1.2 0.4 0.7 1.3 0.5 0.3 0.1 0.3 1.0 1.1 1.9 0.8 2.0 1.1 -0.8 0.9
Alcohol intake frequency. 0.2 0.4 4.7 -0.1 0.0 -0.0 -0.1 0.6 0.7 0.7 0.3 0.6 1.6 0.0 -0.1 -0.1 0.2 0.0 0.1 0.6 -0.1 1.3 -0.4 -0.2 0.1 0.3 0.4 -0.1 1.4 0.3 -0.0 -0.6 -0.2 0.1 1.1 -0.1 0.6 0.3 -0.6 0.1 -0.2 0.3 -0.3 -0.1 0.9 -0.0 0.5 1.0 0.9 -0.2 -2.2 -0.0
Comparative height size at age 10 0.1 0.5 2.4 -1.0 -0.0 -0.0 -0.4 -0.8 -0.8 -0.2 -0.8 -0.3 -1.5 0.0 -0.1 0.0 -0.4 -0.9 -0.3 -0.4 0.0 -1.4 0.4 0.6 -0.1 -0.6 -0.7 0.0 -0.8 -0.5 -0.0 -0.6 0.1 -0.1 -1.1 -0.1 -0.7 -1.1 0.4 0.8 0.2 -0.3 -0.2 -0.4 -1.4 0.0 -0.0 -1.5 -0.3 0.6 1.6 -0.2
Number of full sisters 0.3 0.3 2.9 -0.1 -0.1 -0.1 -0.0 -0.1 0.3 0.4 0.1 1.7 1.5 0.0 -0.2 -0.1 -0.1 -0.4 -0.1 0.6 -0.2 0.7 -0.3 -0.2 -0.1 0.0 0.0 -0.2 1.2 0.0 -0.2 -0.3 -0.2 0.2 0.7 0.2 0.1 0.1 -0.4 0.8 -0.2 1.0 -0.4 -0.5 0.7 -0.4 0.9 0.6 0.5 -0.4 -1.2 0.1
Suffer from ‘nerves’ 0.7 1.1 2.9 -1.1 -1.1 -1.2 -1.3 -0.9 -0.8 -0.9 -1.2 0.2 1.1 0.0 -1.2 -1.2 -1.2 -1.5 -1.2 -0.4 -1.2 -0.7 -1.4 -0.8 -0.6 -1.2 -1.4 -1.2 0.4 -1.1 -1.2 -0.7 -1.1 1.3 -0.4 -0.1 -1.4 -0.3 -1.0 1.0 -1.3 0.9 -1.2 -1.5 0.1 -1.5 0.0 -0.6 -0.7 -1.7 -0.2 -1.1
Overall health rating 0.7 1.5 4.8 -1.1 -1.4 -1.4 -1.3 -1.1 -1.7 -0.9 -1.3 -1.3 0.3 0.0 -1.5 -1.5 -1.3 -2.0 -1.4 -0.8 -1.5 -0.4 -1.6 -2.2 -1.6 -1.3 -1.3 -1.5 0.0 -1.2 -1.5 -1.4 -1.4 1.3 -0.3 -0.8 -1.4 -0.2 -1.3 0.4 -1.2 0.9 -1.0 -1.2 0.1 -1.5 -0.6 -0.4 -1.1 -1.8 -0.6 -1.4
Chest pain or discomfort 0.4 0.5 4.0 -0.3 -0.5 -0.5 -0.5 0.1 -0.3 0.8 0.2 0.7 2.0 0.0 -0.5 -0.5 -0.2 -0.6 -0.3 0.2 -0.5 1.4 -0.8 -0.7 -0.2 0.1 0.0 -0.6 1.4 -0.1 -0.5 -0.2 -0.6 0.7 1.0 -0.1 0.0 0.6 -0.9 0.2 -0.5 1.0 -0.4 -0.2 1.1 -0.6 0.4 1.1 0.4 -0.9 -2.0 -0.3
Had major operations 0.8 1.0 2.4 -0.8 -1.2 -1.1 -1.0 -0.7 -1.6 -0.3 -0.7 -0.4 -1.0 0.0 -1.1 -1.1 -1.0 -1.4 -1.1 -1.1 -1.1 -0.6 -1.4 -1.1 -1.3 -0.7 -0.9 -1.1 -1.1 -1.0 -1.1 -0.9 -1.1 1.4 -0.6 -1.2 -0.8 -0.4 -1.1 -1.1 -1.0 -0.6 -0.7 -0.7 -0.2 -1.1 -1.3 -0.5 -1.3 -1.3 -0.7 -0.9
Age at last live birth 3.0 4.3 6.2 -2.2 -2.1 -2.1 -2.2 -2.2 -1.5 -2.2 -2.3 -1.6 -1.9 0.0 -2.1 -2.1 -2.2 -1.5 -2.2 -2.2 -2.1 -2.2 -2.2 -2.1 -2.1 -2.3 -2.1 -2.1 -1.6 -2.2 -2.1 -2.0 -2.2 1.6 -2.3 -2.3 -2.1 -2.5 -2.2 -2.1 -2.4 -2.2 -2.4 -2.4 -2.2 -2.1 -1.8 -2.2 -1.8 -1.9 -2.0 -2.1
Family relationship satisfaction 0.2 0.3 2.7 0.6 -0.1 -0.0 0.1 0.3 -0.9 -0.2 0.2 0.4 -0.3 0.0 0.1 -0.0 0.2 -0.2 0.1 -0.1 -0.0 0.0 0.4 0.7 0.2 0.3 0.3 -0.0 -1.0 0.2 0.0 1.6 0.0 0.6 0.1 -0.5 0.5 -0.0 -0.1 -1.4 0.2 -1.4 0.5 0.7 -0.6 0.1 -1.0 -0.1 -0.1 0.4 -0.5 -0.2
Leg pain on walking 1.2 1.5 5.8 -1.0 -1.3 -1.2 -1.2 -1.2 -1.5 -1.1 -0.8 -0.6 -1.3 0.0 -1.5 -1.3 -1.2 -1.9 -1.2 -1.5 -1.3 -0.9 -1.4 -1.7 -1.8 -1.0 -1.3 -1.4 -1.1 -1.3 -1.3 -2.4 -1.3 1.2 -0.9 -0.8 -1.4 -0.5 -1.0 -0.6 -1.1 -0.1 -0.9 -1.0 -0.5 -1.4 -1.0 -0.8 -1.6 -1.6 0.1 -1.0
Qualifications: NVQ or HND or HNC or equivalent 0.4 0.4 2.8 0.6 -0.2 -0.1 0.0 -0.5 0.5 0.5 0.6 -0.2 0.9 0.0 -0.3 -0.2 0.2 0.1 0.1 0.1 -0.2 1.3 -0.5 -0.8 -0.4 0.5 0.3 -0.2 0.6 0.2 -0.2 -1.1 -0.1 0.7 1.2 0.5 0.2 1.5 -0.1 0.7 0.1 1.6 0.6 0.5 1.7 -0.2 -0.1 1.4 -0.2 -0.8 0.3 -0.0
Commuting to job workplace: Car/motor vehicle 0.3 0.3 0.9 -0.9 -0.7 -0.7 -0.8 -0.2 0.1 -0.5 -0.4 0.1 0.4 0.0 -0.7 -0.7 -0.7 -0.5 -0.7 -0.2 -0.8 -0.3 -0.8 -0.5 -0.6 -0.5 -0.7 -0.8 -0.1 -0.6 -0.8 0.4 -0.7 0.8 -0.3 -0.6 -0.6 -0.5 -0.8 -0.1 -0.6 0.1 -0.7 -0.7 -0.2 -0.9 -0.2 -0.3 -0.5 -0.7 -0.7 -0.5
Illness, injury, bereavement, stress in last 2 years 0.1 0.2 0.7 -0.7 -0.2 -0.2 -0.1 -0.8 0.6 -0.2 -0.5 0.1 -0.4 0.0 -0.1 -0.2 -0.3 0.4 -0.3 -0.8 -0.2 -0.5 -0.4 -0.1 0.0 -0.5 -0.3 -0.2 0.0 -0.4 -0.2 -0.4 -0.2 0.1 -0.4 -0.4 -0.2 -0.5 -0.3 -0.5 -0.6 -0.7 -0.7 -0.6 -0.3 -0.1 -0.1 -0.3 -0.1 -0.3 -0.7 -0.4
Medication: Aspirin 2.0 2.6 5.5 -1.6 -2.0 -2.1 -1.8 -0.8 -1.3 -1.4 -1.4 -0.8 0.4 0.0 -2.0 -2.1 -1.7 -1.5 -1.9 -1.2 -2.1 -0.5 -2.1 -2.3 -1.8 -1.5 -1.7 -2.0 -0.3 -1.7 -2.0 -1.0 -2.0 2.1 -0.9 -1.6 -1.8 -0.8 -2.1 -1.1 -2.0 -0.0 -1.7 -1.6 -0.6 -2.2 -1.2 -0.8 -1.6 -2.4 -1.8 -1.8
Supplements: Vitamin C 0.1 0.2 1.3 0.7 0.2 0.3 0.2 0.5 0.3 0.3 0.6 1.1 0.2 0.0 0.3 0.3 0.4 0.9 0.4 0.2 0.3 0.4 0.3 0.4 0.4 0.5 0.5 0.2 -0.3 0.4 0.2 0.7 0.3 0.2 0.4 -0.1 0.5 0.4 0.3 -0.2 0.4 -0.1 0.6 0.6 0.2 0.2 -0.4 0.4 0.0 0.3 0.1 0.3
Knee pain experienced in last month 1.8 2.8 5.4 -0.9 -1.8 -1.8 -1.9 -0.9 -2.3 -2.0 -1.6 -0.7 -1.0 0.0 -1.8 -1.8 -1.8 -2.3 -1.8 -1.7 -1.8 -1.6 -1.5 -1.5 -1.5 -1.6 -1.6 -1.8 -1.7 -1.6 -1.8 -1.7 -1.8 2.0 -1.4 -2.1 -1.4 -1.8 -1.9 -1.9 -1.7 -2.1 -1.6 -1.5 -1.8 -1.6 -1.8 -1.7 -1.5 -1.3 -1.8 -1.8
Hypertension (Self-reported) 1.2 3.2 18.9 0.4 0.9 0.8 1.1 1.0 2.3 2.5 1.6 2.7 4.4 0.0 0.8 0.7 1.3 1.1 1.1 2.3 0.8 3.5 0.4 -0.2 1.1 1.5 1.5 0.7 3.8 1.4 0.8 0.9 0.6 -1.3 2.9 1.2 1.5 1.7 0.1 1.9 1.1 3.0 0.6 0.9 2.6 0.7 2.4 2.7 2.4 0.5 -2.3 1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.1 0.2 1.3 -0.3 0.3 0.3 0.3 0.0 0.3 0.4 0.4 -0.4 -0.0 0.0 0.4 0.3 0.3 0.3 0.3 0.4 0.3 0.3 0.1 0.1 0.1 0.4 0.2 0.3 0.4 0.3 0.3 -0.1 0.4 -0.1 0.3 0.4 0.2 0.6 0.4 1.1 0.5 1.1 0.5 0.3 0.7 0.2 0.3 0.4 0.2 0.2 0.8 0.4
Illnesses of father: Heart disease 3.0 4.1 8.2 2.4 1.9 1.9 2.1 2.6 2.9 2.0 2.2 0.9 1.7 0.0 1.9 1.9 2.2 2.8 2.1 2.1 1.9 2.4 1.9 1.7 1.8 2.2 2.4 1.9 1.4 2.3 1.9 2.2 2.0 -1.7 2.4 2.0 2.3 2.3 1.9 1.3 2.1 1.9 2.3 2.3 2.2 1.9 1.6 2.4 1.7 1.7 1.2 2.0
Illnesses of siblings: Diabetes 0.6 0.7 2.2 -1.3 -0.8 -0.8 -0.9 -1.0 -0.5 -0.6 -0.9 0.4 -0.2 0.0 -0.8 -0.9 -0.9 -1.0 -0.9 -0.8 -0.9 -0.5 -0.9 -0.7 -0.9 -1.0 -0.9 -0.9 0.3 -0.9 -0.9 -0.0 -0.9 1.1 -0.7 -0.9 -0.9 -0.9 -1.1 -0.2 -0.9 -0.4 -1.2 -1.1 -0.6 -0.9 -0.3 -0.7 -0.2 -0.7 -1.5 -0.9
Smoking status: Previous 0.3 0.5 2.9 0.9 -0.6 -0.5 -0.2 -0.3 -1.5 -0.3 0.0 -1.4 -0.9 0.0 -0.4 -0.5 -0.1 -0.8 -0.2 -0.9 -0.5 0.1 -0.2 -0.3 -0.6 0.1 -0.1 -0.5 -1.6 -0.1 -0.4 -0.1 -0.3 1.0 0.2 -0.3 -0.1 1.2 -0.0 -0.4 0.2 0.2 1.0 0.9 0.3 -0.4 -1.7 0.3 -1.4 -0.6 1.5 -0.7
Forced expiratory volume in 1-second (FEV1), predicted 0.9 1.9 5.7 -1.4 -1.1 -1.1 -1.4 -1.6 -1.1 -1.5 -1.7 -0.7 -2.1 0.0 -1.1 -1.0 -1.4 -2.0 -1.3 -1.4 -1.0 -2.4 -0.8 -0.6 -1.2 -1.7 -1.8 -1.0 -1.4 -1.6 -1.1 -1.8 -1.0 0.7 -2.2 -0.9 -1.9 -2.0 -0.6 -0.2 -0.9 -0.9 -1.3 -1.6 -2.2 -1.1 -0.7 -2.3 -1.4 -0.6 0.9 -1.0
Whole body fat-free mass 0.3 1.9 3.8 1.8 1.4 1.4 1.4 1.1 0.5 1.4 1.3 0.7 1.1 0.0 1.4 1.4 1.5 0.4 1.5 1.2 1.4 1.5 1.6 1.6 1.4 1.4 1.5 1.4 0.6 1.6 1.4 1.5 1.5 -1.5 1.7 1.6 1.5 1.5 1.6 1.4 1.6 1.3 1.8 1.7 1.2 1.4 1.2 1.4 0.9 1.4 2.0 1.3
Leg fat-free mass (right) 0.4 2.3 4.3 1.8 1.4 1.4 1.5 1.3 0.7 1.5 1.4 0.7 1.3 0.0 1.4 1.4 1.6 0.6 1.6 1.3 1.4 1.8 1.5 1.4 1.4 1.5 1.6 1.4 0.9 1.7 1.4 1.6 1.5 -1.4 2.0 1.9 1.6 2.0 1.7 1.7 1.7 1.9 1.9 1.8 1.7 1.5 1.4 1.8 1.0 1.2 2.1 1.4
Arm fat percentage (left) 0.2 0.7 2.8 0.9 0.6 0.6 0.9 1.7 0.2 0.5 0.7 1.6 1.3 0.0 0.6 0.6 0.7 0.8 0.7 0.9 0.6 1.1 0.8 0.2 0.8 0.7 1.0 0.6 0.9 0.9 0.6 1.7 0.5 -0.9 1.0 0.2 1.1 0.1 0.1 -0.5 0.5 -0.5 0.2 0.6 0.2 0.7 0.9 0.7 1.2 0.9 -1.5 0.7
Average weekly red wine intake 0.5 0.7 2.5 0.8 1.0 0.9 0.9 0.3 1.0 0.5 0.5 -0.2 -0.7 0.0 1.0 1.0 0.7 1.1 0.8 0.3 1.0 0.0 1.6 1.1 0.7 0.6 0.8 1.0 -0.1 0.8 1.0 0.6 1.0 -1.2 0.3 0.6 0.8 -0.1 1.0 0.5 1.0 -0.4 0.8 0.8 -0.6 1.2 0.8 -0.2 0.8 1.6 1.0 0.7
Handedness (chirality/laterality): Left-handed 0.1 0.1 0.9 0.3 -0.1 -0.1 -0.0 0.2 -0.6 -0.2 0.0 -0.3 0.6 0.0 -0.1 -0.1 -0.1 -0.2 -0.1 -0.3 -0.1 0.2 0.1 0.3 0.2 0.1 0.2 -0.1 -0.3 0.3 -0.1 0.9 0.0 0.2 0.9 0.3 0.4 0.6 0.1 0.5 -0.0 0.2 0.4 0.3 0.6 0.1 0.0 0.4 -0.2 -0.2 0.7 -0.1
Mood swings 2.5 4.6 10.1 -1.8 -2.5 -2.6 -2.6 -2.4 -2.7 -1.6 -2.2 -2.1 -0.2 0.0 -2.6 -2.6 -2.4 -2.7 -2.5 -1.9 -2.6 -1.0 -2.8 -2.4 -2.4 -2.2 -2.3 -2.6 -1.0 -2.2 -2.5 -2.1 -2.5 2.7 -1.1 -1.6 -2.3 -0.8 -2.4 -0.5 -2.5 0.3 -1.9 -2.2 -0.4 -2.8 -1.6 -1.0 -2.5 -3.2 -0.8 -2.4
Loneliness, isolation 5.1 7.0 10.2 -2.8 -2.8 -2.9 -2.8 -2.6 -2.7 -2.8 -3.0 -1.9 -2.1 0.0 -2.8 -2.8 -3.0 -2.6 -3.0 -2.5 -2.8 -3.0 -3.0 -2.7 -2.8 -3.0 -3.1 -2.8 -2.1 -3.0 -2.8 -2.1 -2.7 3.1 -2.9 -2.5 -3.2 -2.3 -2.5 -1.5 -2.9 -1.4 -2.7 -2.9 -2.1 -2.9 -2.3 -2.7 -2.9 -2.9 -0.8 -2.8
Long-standing illness, disability or infirmity 0.1 0.1 0.6 0.4 -0.3 -0.3 -0.0 0.1 -0.5 -0.2 0.2 -0.6 -0.2 0.0 -0.3 -0.3 -0.0 -0.6 -0.1 -0.3 -0.3 0.4 -0.1 -0.6 -0.4 0.1 0.0 -0.3 -0.4 0.0 -0.3 0.1 -0.2 0.6 0.4 -0.2 -0.0 0.7 -0.1 0.1 0.2 0.4 0.5 0.5 0.4 -0.1 -0.8 0.3 -0.5 -0.3 0.6 -0.3
Ever had bowel cancer screening 1.7 2.0 4.3 -1.5 -1.8 -1.8 -1.6 -1.4 -1.7 -1.6 -1.3 -0.2 -0.4 0.0 -1.7 -1.8 -1.5 -1.7 -1.6 -1.1 -1.8 -0.7 -1.9 -2.0 -1.8 -1.4 -1.5 -1.8 -1.0 -1.5 -1.7 -0.2 -1.7 1.8 -0.9 -1.3 -1.6 -0.5 -1.6 -0.7 -1.4 0.3 -1.0 -1.2 -0.4 -1.9 -1.5 -0.7 -2.0 -2.1 -0.3 -1.6
Diabetes diagnosed by doctor 0.5 0.8 3.6 0.0 -0.9 -0.9 -0.6 -0.4 0.2 0.2 -0.1 1.2 1.9 0.0 -0.9 -1.0 -0.4 -0.4 -0.5 -0.1 -1.0 1.5 -1.2 -1.3 -0.6 -0.1 -0.1 -1.0 0.5 -0.2 -0.9 -0.8 -0.9 1.0 1.0 -0.4 -0.1 0.9 -1.2 -0.7 -0.9 0.9 -0.2 -0.1 1.2 -1.1 -0.5 1.2 -0.5 -1.6 -1.6 -0.8
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.8 1.6 0.2 1.0 0.9 0.7 0.7 0.8 1.1 0.9 0.3 0.6 0.0 0.9 1.0 0.9 0.9 0.9 1.3 1.0 0.6 1.0 1.0 0.9 0.9 0.7 1.0 0.9 0.8 1.0 0.5 1.0 -1.1 0.5 1.2 0.6 0.6 1.0 1.2 1.0 1.0 0.7 0.6 0.5 0.8 1.1 0.5 1.0 0.9 1.0 1.1
Friendships satisfaction 0.1 0.1 1.3 0.4 -0.1 -0.1 0.0 0.1 -0.5 -0.0 0.3 -0.4 0.2 0.0 -0.1 -0.1 0.0 0.0 -0.0 -0.1 -0.1 0.1 0.2 0.2 0.1 0.3 0.1 -0.1 -0.5 0.1 -0.1 1.1 -0.0 0.3 0.5 0.1 0.3 0.5 0.1 -0.1 0.2 -0.2 0.5 0.6 0.1 0.1 -0.5 0.2 -0.2 0.0 0.5 -0.1
Qualifications: nursing, teaching 0.9 1.4 4.0 0.8 1.4 1.4 1.3 0.9 1.2 1.5 1.1 1.2 0.9 0.0 1.4 1.4 1.3 2.0 1.3 0.9 1.4 1.1 1.4 1.3 1.4 1.2 1.5 1.4 1.3 1.3 1.4 0.2 1.3 -1.6 1.2 1.1 1.5 0.9 1.0 0.5 0.9 -0.1 0.7 0.9 1.0 1.4 1.2 1.1 1.7 1.3 -0.5 1.0
Commuting to job workplace: Walk 0.5 0.5 1.7 0.4 0.6 0.5 0.7 1.1 1.3 1.1 0.8 1.0 1.1 0.0 0.5 0.5 0.6 0.5 0.6 0.8 0.6 1.0 0.1 -0.0 0.5 0.7 0.5 0.5 1.3 0.6 0.5 0.2 0.5 -0.8 0.7 0.8 0.5 0.7 0.3 0.5 0.3 0.9 0.1 0.1 1.2 0.4 1.0 1.0 0.7 0.0 -0.4 0.8
Eye problems/disorders: Cataract 0.3 0.3 1.5 0.6 0.4 0.3 0.6 0.2 0.2 0.6 0.8 0.6 0.5 0.0 0.3 0.3 0.6 0.5 0.5 0.3 0.3 0.9 0.1 -0.2 0.3 0.7 0.6 0.4 0.5 0.5 0.4 -0.5 0.4 0.0 0.6 0.5 0.4 1.2 0.3 0.2 0.5 0.9 0.7 0.7 1.2 0.3 -0.0 1.1 0.2 -0.1 0.2 0.3
Mouth/teeth dental problems: Mouth ulcers 1.1 1.8 3.6 1.6 1.3 1.3 1.4 1.0 0.1 1.6 1.7 0.9 1.6 0.0 1.2 1.3 1.6 1.0 1.5 1.9 1.3 1.8 1.2 1.2 1.6 1.6 1.5 1.3 0.9 1.5 1.3 0.5 1.3 -1.4 1.6 1.4 1.4 1.7 1.3 0.9 1.5 1.6 1.8 1.6 1.5 1.1 0.6 1.8 0.9 1.0 1.1 1.2
Medication for cholesterol 0.4 0.6 5.0 0.7 -0.3 -0.3 -0.5 -0.3 -0.8 -1.5 -0.5 -0.7 -2.0 0.0 -0.2 -0.2 -0.5 0.2 -0.4 -0.9 -0.2 -1.6 -0.0 0.2 -0.4 -0.4 -0.4 -0.2 -2.2 -0.4 -0.2 -0.2 -0.1 0.5 -1.1 -0.4 -0.3 -0.4 0.2 -0.9 -0.3 -1.4 0.1 -0.1 -0.9 -0.2 -1.3 -1.0 -1.4 -0.2 1.6 -0.5
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 1.3 -1.1 -0.7 -0.7 -0.8 -0.9 -0.9 -0.3 -1.0 -0.2 0.0 0.0 -0.7 -0.7 -0.8 -0.5 -0.8 -0.3 -0.7 -0.7 -0.5 -0.6 -0.5 -0.9 -0.9 -0.7 -0.5 -0.7 -0.7 -0.5 -0.6 0.5 -0.6 -0.3 -1.0 -0.5 -0.3 0.9 -0.6 0.5 -0.4 -0.7 -0.6 -0.7 -0.5 -0.9 -0.8 -0.7 1.1 -0.9
Back pain experienced in last month 0.7 1.0 4.6 -0.2 -0.8 -0.8 -0.8 -0.6 -1.6 -1.4 -0.9 -0.9 -1.3 0.0 -0.8 -0.8 -0.8 -2.1 -0.8 -0.9 -0.8 -1.2 -0.5 -0.6 -0.7 -0.9 -0.9 -0.8 -1.6 -0.9 -0.8 0.4 -0.8 1.2 -1.3 -1.2 -0.8 -1.1 -0.7 -1.3 -0.6 -1.5 -0.6 -0.6 -1.5 -0.8 -1.4 -1.3 -1.1 -0.4 -0.3 -1.0
Mineral and other dietary supplements 0.4 0.5 4.3 -0.9 0.3 0.2 0.2 -0.4 0.7 1.0 0.2 1.2 1.2 0.0 0.2 0.2 0.2 -0.3 0.2 0.6 0.2 0.9 -0.2 -0.5 0.1 0.2 0.1 0.2 2.1 0.1 0.2 -1.4 0.1 -0.3 0.6 0.8 0.0 0.5 -0.1 1.1 -0.0 1.5 -0.3 -0.3 1.1 -0.0 1.3 0.8 1.1 -0.3 -0.9 0.4
Breast cancer (self-reported) 0.1 0.1 0.9 0.1 0.2 0.1 0.2 0.2 0.4 -0.2 0.1 -0.7 -0.3 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 -0.0 0.2 -0.2 -0.3 0.1 0.0 0.2 0.2 0.1 0.2 0.1 0.2 -0.5 -0.0 0.4 -0.1 0.1 0.3 0.5 0.2 0.7 0.1 0.0 0.0 0.2 0.3 0.1 -0.2 0.0 1.0 0.3
Asthma (self-reported) 0.1 0.2 1.4 0.4 -0.4 -0.4 -0.1 0.2 -0.2 0.0 0.2 -0.9 0.8 0.0 -0.4 -0.4 -0.1 0.3 -0.2 -0.4 -0.4 0.8 -0.3 -0.7 -0.2 0.2 0.1 -0.4 0.4 0.0 -0.4 -0.6 -0.3 0.5 0.9 0.0 0.1 1.2 -0.4 0.2 -0.1 0.6 0.2 0.4 1.0 -0.2 -0.2 0.8 -0.1 -0.6 -0.4 -0.4
Osteoporosis (self-reported) 0.1 0.1 2.2 0.1 -0.1 -0.1 -0.0 0.2 0.3 0.0 0.0 -0.6 -0.8 0.0 0.0 -0.0 -0.0 0.6 -0.0 -0.1 -0.0 -0.3 0.3 0.3 -0.2 0.1 -0.0 -0.0 -0.9 0.0 -0.0 0.1 0.1 0.3 -0.1 0.0 -0.1 0.1 0.3 0.2 0.2 0.0 0.5 0.3 -0.4 -0.0 -0.7 -0.3 -0.6 0.1 1.5 -0.2
Osteoarthritis (self-reported) 0.1 0.1 1.3 -0.2 0.1 0.0 0.2 0.4 0.9 -0.2 0.1 1.1 0.6 0.0 0.2 0.0 -0.0 0.5 0.0 -0.0 0.0 -0.0 0.0 0.2 0.3 -0.0 0.0 0.0 0.5 -0.0 0.0 1.1 0.0 0.2 0.0 0.3 -0.0 0.0 -0.1 -0.3 -0.6 -0.4 -0.5 -0.3 0.2 0.1 0.3 0.1 0.4 -0.3 -0.6 -0.1
Medication: Aspirin 1.8 2.3 4.4 -1.5 -1.9 -1.9 -1.6 -0.7 -1.3 -1.5 -1.3 -0.6 0.2 0.0 -1.9 -1.9 -1.6 -1.4 -1.7 -1.1 -1.9 -0.5 -1.9 -2.0 -1.6 -1.5 -1.6 -1.9 -0.3 -1.6 -1.9 -0.6 -1.9 1.9 -1.0 -1.6 -1.7 -1.0 -2.1 -1.4 -1.9 -0.4 -1.7 -1.6 -0.8 -2.0 -1.2 -0.9 -1.4 -2.1 -1.9 -1.7
Medication: Gliclazide 1.5 1.7 7.1 1.4 0.8 0.8 1.1 0.6 2.7 1.7 1.4 2.5 2.3 0.0 0.8 0.8 1.1 1.1 1.1 0.9 0.8 2.1 0.7 0.7 1.1 1.4 1.4 0.8 1.3 1.3 0.8 0.6 0.8 -0.5 2.0 1.5 1.4 2.1 0.7 0.7 0.7 1.4 1.2 1.3 2.2 0.6 0.9 2.1 1.0 0.2 0.1 0.8
Illnesses of father: None of the above (group 1) 0.3 0.4 1.7 -0.3 -0.5 -0.4 -0.3 -0.7 -0.8 -0.9 -0.5 -0.6 -1.0 0.0 -0.4 -0.4 -0.6 -0.7 -0.6 -1.0 -0.4 -1.1 -0.3 0.0 -0.2 -0.5 -0.6 -0.4 -1.2 -0.6 -0.4 0.2 -0.4 0.5 -0.9 -0.7 -0.5 -0.7 -0.4 -0.9 -0.5 -1.3 -0.5 -0.5 -0.9 -0.4 -0.8 -0.9 -0.8 -0.3 0.0 -0.5
Smoking status: Current 2.7 4.4 11.0 -2.0 -2.3 -2.3 -2.1 -2.6 -2.1 -2.5 -2.1 -3.3 -1.7 0.0 -2.3 -2.3 -2.4 -2.8 -2.3 -2.2 -2.3 -1.9 -2.1 -2.8 -2.4 -2.2 -2.4 -2.3 -1.4 -2.4 -2.3 -1.0 -2.2 1.9 -1.8 -1.8 -2.5 -1.5 -1.9 -0.5 -1.9 -0.4 -1.8 -1.9 -1.6 -2.2 -1.7 -2.0 -2.2 -2.2 -0.3 -2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.5 1.1 8.5 1.9 0.8 0.9 1.0 0.6 0.4 -0.2 0.8 -1.5 -1.2 0.0 0.9 0.9 0.9 0.7 0.9 0.1 0.8 -0.1 1.2 1.6 0.8 0.9 0.8 0.9 -1.5 0.9 0.9 1.4 1.0 -0.4 0.2 0.8 0.8 1.1 1.4 -0.1 1.1 -0.2 1.7 1.6 0.0 1.0 -0.8 0.3 -0.6 0.9 2.9 0.5
Whole body water mass 0.4 2.1 4.2 1.9 1.4 1.5 1.4 1.2 0.6 1.5 1.3 0.7 1.0 0.0 1.4 1.4 1.5 0.4 1.5 1.3 1.4 1.5 1.6 1.7 1.5 1.4 1.5 1.4 0.6 1.6 1.4 1.5 1.5 -1.6 1.7 1.7 1.5 1.5 1.7 1.4 1.7 1.4 1.8 1.7 1.2 1.5 1.3 1.4 1.0 1.4 2.0 1.4
Leg predicted mass (right) 0.4 2.1 4.2 1.8 1.3 1.4 1.4 1.3 0.6 1.4 1.4 0.7 1.3 0.0 1.3 1.3 1.5 0.5 1.5 1.2 1.3 1.7 1.5 1.4 1.4 1.5 1.5 1.3 0.9 1.6 1.4 1.6 1.5 -1.4 1.9 1.8 1.5 1.9 1.6 1.7 1.6 1.8 1.8 1.7 1.6 1.4 1.4 1.7 1.0 1.2 2.0 1.4
Arm fat mass (left) 0.3 1.2 3.4 1.4 1.0 1.1 1.3 1.8 0.2 0.9 1.0 1.6 1.2 0.0 1.1 1.0 1.1 0.9 1.2 1.1 1.0 1.3 1.3 0.9 1.2 1.1 1.3 1.0 0.8 1.3 1.0 1.9 1.0 -1.3 1.3 0.7 1.5 0.5 0.8 -0.0 1.0 -0.1 0.8 1.1 0.5 1.2 1.1 1.0 1.4 1.4 -0.5 1.0
Number of self-reported non-cancer illnesses 4.8 8.3 13.0 -3.2 -3.3 -3.3 -3.1 -3.0 -2.1 -2.7 -3.0 -1.7 -1.3 0.0 -3.2 -3.3 -3.1 -3.1 -3.2 -2.9 -3.3 -1.8 -3.1 -3.4 -3.4 -3.0 -2.9 -3.3 -1.4 -3.0 -3.3 -2.3 -3.4 3.0 -2.1 -3.2 -2.9 -2.7 -3.6 -2.6 -3.3 -2.0 -3.2 -2.9 -2.5 -3.3 -2.3 -2.4 -2.3 -3.1 -3.5 -3.2
Average weekly champagne plus white wine intake 0.2 0.2 2.7 -0.2 0.2 0.2 0.1 0.0 0.4 0.7 0.3 1.7 0.8 0.0 0.2 0.1 0.3 -0.2 0.2 0.3 0.1 0.7 -0.2 -0.2 0.1 0.3 0.3 0.1 0.8 0.3 0.2 -0.2 0.1 0.0 0.7 0.2 0.3 0.6 0.0 0.6 0.0 1.0 0.1 -0.0 1.1 -0.1 0.4 0.8 0.2 -0.3 -0.4 0.2
Miserableness 1.4 2.5 6.0 -1.1 -1.8 -1.9 -1.7 -2.1 -1.3 -1.3 -1.6 -1.9 -0.2 0.0 -1.9 -1.9 -1.6 -2.3 -1.7 -1.4 -1.9 -0.6 -2.2 -2.3 -1.9 -1.6 -1.6 -1.9 -0.7 -1.6 -1.8 -2.2 -1.8 1.8 -0.6 -1.1 -1.7 -0.2 -1.6 -0.2 -1.7 0.7 -1.2 -1.4 0.2 -2.0 -1.2 -0.4 -2.0 -2.5 -0.3 -1.9
Guilty feelings 0.2 0.2 1.9 -0.5 -0.2 -0.3 -0.4 -0.6 -1.3 -0.1 -0.4 -0.3 0.1 0.0 -0.3 -0.2 -0.4 -1.1 -0.3 -0.2 -0.3 -0.3 -0.4 -0.4 -0.3 -0.3 -0.4 -0.3 -0.2 -0.2 -0.3 -0.5 -0.1 0.3 0.1 0.3 -0.4 0.2 0.1 1.4 -0.0 1.1 0.1 -0.3 0.4 -0.4 0.2 -0.1 -0.6 -0.5 1.3 -0.2
Wears glasses or contact lenses 0.2 0.2 1.1 -0.5 0.5 0.4 0.6 0.1 0.4 0.1 0.3 0.5 0.5 0.0 0.5 0.5 0.3 0.1 0.4 0.7 0.5 0.3 0.4 0.0 0.4 0.3 0.3 0.5 0.9 0.4 0.5 1.0 0.5 -0.6 0.3 0.5 0.3 -0.0 0.4 1.0 0.4 0.7 0.0 -0.1 0.3 0.4 1.0 0.2 0.7 0.5 0.1 0.6
Ever taken oral contraceptive pill 2.2 2.5 8.0 -2.8 -1.3 -1.4 -1.5 -2.3 -1.1 -1.6 -1.8 -1.6 -1.6 0.0 -1.4 -1.3 -1.7 -2.6 -1.6 -1.4 -1.3 -2.2 -1.3 -1.3 -1.4 -1.9 -2.0 -1.3 -0.8 -1.9 -1.4 -1.1 -1.3 0.7 -2.2 -1.1 -2.2 -2.0 -1.0 0.2 -1.3 -0.2 -1.8 -2.1 -1.8 -1.6 -0.4 -2.1 -1.4 -1.1 0.2 -1.2
Hearing aid user 2.1 2.4 9.7 0.8 1.5 1.4 1.4 0.2 2.0 1.8 1.2 1.2 1.8 0.0 1.3 1.5 1.3 0.9 1.3 1.7 1.5 1.5 1.1 0.5 1.0 1.3 1.2 1.5 2.4 1.4 1.4 -0.0 1.4 -1.7 1.7 2.0 1.3 1.5 1.4 3.1 1.4 2.7 1.1 0.8 2.2 1.2 2.5 1.6 2.0 1.1 0.9 1.6
Mother’s age at death 4.2 5.2 9.3 2.9 2.1 2.2 2.4 2.5 2.4 2.5 2.7 2.9 2.4 0.0 2.2 2.2 2.4 2.4 2.3 2.2 2.1 2.7 2.2 2.4 2.2 2.7 2.7 2.1 1.3 2.7 2.2 2.0 2.2 -1.8 3.0 2.1 3.0 2.6 2.0 1.2 2.2 1.2 2.5 2.6 2.4 2.1 1.6 2.7 2.1 2.0 0.9 2.1
Financial situation satisfaction 0.5 0.7 1.8 -1.0 -1.0 -1.0 -0.9 -0.7 -1.0 -0.2 -0.7 -1.0 -0.6 0.0 -1.0 -1.0 -0.9 -0.6 -0.9 -0.7 -1.0 -0.5 -1.1 -1.4 -1.3 -0.7 -0.9 -1.0 -0.5 -0.9 -1.0 -0.7 -0.9 1.0 -0.4 -0.7 -0.9 -0.0 -0.8 0.2 -0.7 0.4 -0.5 -0.7 0.1 -1.1 -0.8 -0.3 -1.1 -1.1 -0.1 -0.8
Tinnitus: Yes, now most or all of the time 1.1 1.3 8.0 -0.5 1.1 1.0 1.2 0.1 2.4 1.4 0.9 1.1 1.4 0.0 0.9 1.0 0.9 1.2 1.0 1.1 0.9 1.3 0.4 -0.1 0.7 0.7 0.7 0.9 2.8 0.7 0.9 0.2 0.8 -1.5 0.7 1.0 0.5 0.4 0.6 1.5 0.7 1.8 -0.2 -0.1 1.2 0.8 2.2 1.1 1.7 0.7 -1.1 1.3
Commuting to job workplace: Public transport 0.1 0.1 0.6 -0.2 -0.1 -0.1 -0.2 -0.6 -0.3 -0.1 -0.6 -0.8 -0.8 0.0 -0.1 -0.1 -0.2 -0.3 -0.2 -0.3 -0.1 -0.6 -0.1 -0.6 -0.3 -0.6 -0.3 -0.1 -0.2 -0.3 -0.1 -0.6 -0.1 -0.1 -0.6 -0.3 -0.4 -0.5 -0.0 -0.0 -0.2 -0.2 -0.3 -0.4 -0.6 -0.1 -0.1 -0.6 -0.2 0.0 0.2 -0.3
Eye problems/disorders: Glaucoma 0.4 0.5 2.7 0.6 0.6 0.7 0.6 1.3 1.6 0.7 0.9 0.5 1.0 0.0 0.6 0.6 0.7 1.1 0.7 0.8 0.6 0.9 0.7 0.7 0.9 0.8 0.8 0.6 0.7 0.7 0.6 0.3 0.6 -0.7 0.8 0.3 0.8 0.5 0.4 0.5 0.8 0.4 0.6 0.7 0.5 0.6 0.5 0.6 0.9 0.8 -0.3 0.6
Medication: Blood pressure 0.5 1.0 6.7 0.0 0.4 0.3 0.5 1.0 1.2 1.5 0.7 1.8 2.6 0.0 0.3 0.3 0.6 0.5 0.5 1.1 0.3 2.0 0.3 0.1 0.7 0.7 0.8 0.3 2.2 0.7 0.3 0.7 0.2 -0.6 1.5 0.3 0.8 0.4 -0.3 0.3 0.4 0.8 0.0 0.4 0.8 0.4 1.3 1.2 1.7 0.4 -2.3 0.6
Pain type(s) experienced in last month: Hip pain 5.4 6.8 13.8 -2.2 -2.6 -2.6 -2.6 -3.0 -3.0 -3.2 -2.9 -2.2 -2.4 0.0 -2.6 -2.6 -2.8 -3.7 -2.8 -2.4 -2.6 -3.0 -2.5 -2.8 -2.7 -2.9 -2.9 -2.6 -2.4 -2.8 -2.6 -1.7 -2.6 2.4 -2.9 -2.6 -2.9 -2.9 -2.4 -2.0 -2.6 -1.9 -2.6 -2.8 -2.8 -2.7 -2.2 -2.9 -2.8 -2.3 -1.1 -2.5
Supplements: Fish oil (including cod liver oil) 0.4 0.6 3.1 0.2 -0.5 -0.5 -0.6 -0.3 -1.2 -1.2 -0.7 -1.1 -1.2 0.0 -0.5 -0.5 -0.6 -0.2 -0.5 -0.7 -0.5 -1.2 -0.0 0.0 -0.5 -0.6 -0.5 -0.5 -1.8 -0.5 -0.5 0.3 -0.4 0.4 -1.0 -0.9 -0.5 -1.0 -0.2 -1.0 -0.4 -1.4 -0.2 -0.3 -1.4 -0.3 -1.1 -1.2 -1.0 0.0 0.5 -0.6
High cholesterol (Self-reported) 0.7 1.3 3.7 -1.5 -1.3 -1.3 -1.1 -1.1 -0.5 -0.3 -1.2 -0.4 0.4 0.0 -1.3 -1.3 -1.2 -0.8 -1.2 -0.6 -1.3 -0.3 -1.3 -1.4 -1.0 -1.2 -1.2 -1.3 0.1 -1.2 -1.3 -0.4 -1.4 1.1 -0.8 -1.2 -1.2 -1.2 -1.6 -1.2 -1.5 -0.4 -1.5 -1.4 -1.0 -1.4 -0.5 -0.8 -0.7 -1.3 -1.9 -1.3
Medication: Bendroflumethiazide 0.6 0.9 4.8 -1.1 -0.9 -1.0 -0.8 -1.1 -0.3 0.2 -1.0 0.1 1.0 0.0 -1.0 -1.0 -0.9 -0.6 -1.0 -0.1 -1.0 0.1 -1.3 -1.6 -0.9 -1.0 -0.9 -1.0 1.3 -0.9 -1.0 -0.6 -1.1 0.3 -0.2 -0.8 -0.9 -1.0 -1.4 0.3 -1.1 0.6 -1.5 -1.5 -0.2 -1.1 0.5 -0.3 0.0 -1.0 -2.2 -0.7
Medication: Paracetamol 3.0 4.6 8.8 -1.9 -2.5 -2.5 -2.4 -2.4 -2.2 -2.5 -2.0 -2.6 -1.0 0.0 -2.6 -2.5 -2.3 -2.6 -2.4 -2.0 -2.5 -1.3 -2.6 -3.0 -2.6 -2.1 -2.3 -2.5 -1.2 -2.3 -2.5 -2.4 -2.5 2.3 -1.5 -2.1 -2.4 -1.2 -2.4 -1.0 -2.2 -0.1 -1.8 -2.0 -0.9 -2.6 -1.9 -1.3 -2.4 -2.7 -1.2 -2.3
Medication: Lisinopril 0.1 0.1 1.5 -0.3 0.2 0.2 0.3 0.1 1.2 0.2 0.1 0.6 0.5 0.0 0.3 0.2 0.3 0.2 0.2 0.1 0.2 0.4 0.1 0.0 0.3 0.1 0.3 0.2 0.5 0.2 0.2 0.6 0.1 -0.4 0.2 -0.2 0.4 -0.1 -0.1 -0.5 -0.0 -0.4 -0.2 0.0 0.0 0.1 0.2 0.3 0.5 0.2 -1.2 0.1
Medication: Atorvastatin 1.4 1.8 4.4 -2.1 -1.3 -1.4 -1.4 -1.8 -0.7 -0.9 -1.7 -0.6 -0.1 0.0 -1.3 -1.3 -1.6 -1.4 -1.6 -0.5 -1.3 -1.5 -1.6 -1.7 -1.1 -1.7 -1.8 -1.3 -0.1 -1.7 -1.4 -0.7 -1.4 1.0 -1.7 -1.1 -2.0 -1.6 -1.3 0.4 -1.3 0.3 -1.7 -2.0 -1.0 -1.6 -0.2 -1.6 -1.0 -1.3 -0.5 -1.1
Illnesses of father: High blood pressure 1.0 1.2 3.2 1.2 1.0 0.9 0.9 1.2 0.6 1.4 1.1 0.2 1.6 0.0 0.9 0.9 1.1 0.5 1.0 1.3 0.9 1.8 0.7 0.6 0.9 1.2 1.3 0.9 1.6 1.2 1.0 0.4 0.9 -0.9 1.7 1.1 1.3 1.5 0.6 1.2 0.9 1.3 1.0 1.1 1.8 0.9 1.1 1.7 1.4 0.7 -0.3 1.0
Alcohol drinker status: Never 0.4 0.5 3.8 0.3 0.4 0.3 0.3 0.6 1.3 1.0 0.5 0.9 1.9 0.0 0.4 0.4 0.4 0.7 0.3 1.4 0.4 0.9 0.2 0.5 0.8 0.5 0.5 0.4 1.3 0.5 0.4 0.2 0.3 -0.7 0.9 0.4 0.6 0.2 0.0 0.9 0.3 0.9 0.1 0.0 0.7 0.2 1.1 0.8 1.0 0.3 -0.9 0.5
Ever smoked 2.0 3.5 9.7 -0.9 -2.1 -2.1 -1.6 -2.0 -2.6 -2.0 -1.4 -3.1 -2.3 0.0 -2.0 -2.1 -1.7 -2.4 -1.8 -2.5 -2.1 -1.2 -1.7 -2.2 -2.4 -1.5 -1.8 -2.1 -2.5 -1.8 -2.1 -0.9 -1.8 2.3 -1.2 -1.5 -2.0 -0.1 -1.4 -1.1 -1.3 -0.2 -0.4 -0.6 -0.9 -2.0 -2.7 -1.2 -2.9 -2.2 1.2 -2.1
Basal metabolic rate 0.3 1.9 2.9 1.7 1.4 1.4 1.4 1.2 0.5 1.4 1.2 1.0 1.1 0.0 1.4 1.4 1.4 0.4 1.5 1.2 1.4 1.4 1.6 1.6 1.5 1.4 1.5 1.4 0.6 1.6 1.4 1.6 1.5 -1.5 1.6 1.6 1.5 1.3 1.6 1.3 1.6 1.2 1.6 1.6 1.1 1.5 1.3 1.3 1.1 1.4 1.7 1.4
Leg fat percentage (left) 0.1 0.5 3.9 0.3 0.5 0.5 0.7 1.0 -0.3 0.6 0.6 1.9 0.7 0.0 0.6 0.5 0.6 0.7 0.6 0.6 0.5 0.8 0.6 0.1 0.5 0.6 0.8 0.5 0.6 0.7 0.5 1.5 0.4 -0.6 0.5 -0.2 1.0 -0.3 -0.0 -1.0 0.3 -1.1 -0.0 0.4 -0.2 0.5 0.5 0.4 1.1 0.9 -2.0 0.5
Arm fat-free mass (left) 0.4 2.0 2.8 1.6 1.4 1.5 1.5 1.2 0.2 1.5 1.3 1.1 1.1 0.0 1.5 1.5 1.5 0.3 1.6 1.3 1.5 1.5 1.7 1.6 1.5 1.4 1.6 1.5 0.7 1.7 1.5 1.6 1.6 -1.6 1.7 1.6 1.6 1.4 1.6 1.3 1.6 1.1 1.7 1.6 1.1 1.6 1.4 1.4 1.2 1.5 1.6 1.4
Number of operations (self-reported) 0.1 0.2 0.8 0.2 -0.5 -0.5 -0.3 -0.4 -0.3 -0.4 -0.3 -0.5 -0.2 0.0 -0.4 -0.5 -0.4 -0.9 -0.4 -0.8 -0.5 0.1 -0.4 -0.6 -0.4 -0.2 -0.1 -0.5 -0.5 -0.2 -0.5 -0.4 -0.5 0.7 0.2 -0.8 0.0 -0.0 -0.7 -0.7 -0.4 -0.6 -0.1 0.0 -0.0 -0.3 -0.7 0.0 -0.5 -0.4 -0.8 -0.6
Average weekly beer plus cider intake 0.1 0.2 3.2 0.9 0.2 0.2 0.2 -0.0 -0.4 -0.1 0.2 -1.1 -0.4 0.0 0.2 0.2 0.1 -0.7 0.2 -0.1 0.2 -0.2 0.3 0.3 0.1 0.2 -0.0 0.2 -0.3 0.2 0.2 -0.1 0.3 -0.1 0.1 0.6 -0.0 0.7 0.6 0.8 0.4 0.4 0.6 0.5 0.4 0.4 0.0 0.1 -0.3 0.1 1.8 0.2
Irritability 1.1 1.9 4.9 -1.3 -1.7 -1.7 -1.5 -1.8 -1.8 -1.0 -1.4 -0.8 0.5 0.0 -1.6 -1.7 -1.4 -1.5 -1.5 -1.0 -1.7 -0.4 -2.0 -2.0 -1.2 -1.4 -1.4 -1.7 -0.6 -1.4 -1.7 -0.8 -1.6 1.8 -0.6 -1.2 -1.5 -0.1 -1.5 -0.3 -1.4 0.8 -0.9 -1.1 0.1 -1.9 -1.4 -0.3 -1.9 -2.2 -0.4 -1.7
Risk taking 0.4 0.7 4.3 1.4 0.5 0.6 0.7 0.5 0.5 0.2 0.7 -1.2 -0.8 0.0 0.6 0.6 0.7 0.5 0.7 -0.0 0.6 0.3 1.1 0.8 0.3 0.8 0.8 0.6 -1.0 0.8 0.6 0.6 0.8 -0.0 0.9 0.7 0.9 1.3 1.0 0.4 1.0 0.1 1.6 1.5 0.5 0.8 -0.4 0.5 -0.1 0.8 2.1 0.3
Ever had prostate specific antigen (PSA) test 0.3 0.3 1.8 -1.0 -0.3 -0.4 -0.4 -0.9 -0.3 -0.3 -0.8 0.8 -0.1 0.0 -0.3 -0.3 -0.4 -0.4 -0.4 -0.3 -0.4 -0.5 -0.4 0.1 -0.2 -0.7 -0.4 -0.4 -0.1 -0.5 -0.4 0.1 -0.4 0.3 -0.6 -0.7 -0.3 -1.2 -0.6 -0.9 -0.7 -1.0 -0.9 -0.8 -1.0 -0.4 -0.1 -0.7 -0.0 -0.2 -1.3 -0.5
Fractured/broken bones in last 5 years 0.9 1.2 3.1 -0.2 1.1 1.1 1.1 1.1 0.7 1.0 0.9 0.7 1.2 0.0 1.2 1.1 1.1 0.6 1.1 1.2 1.1 1.2 1.1 0.6 1.0 0.9 1.1 1.1 1.5 1.2 1.1 1.8 1.1 -1.3 1.2 1.3 1.0 0.9 1.1 1.5 1.0 1.4 0.8 0.8 1.2 1.2 1.6 1.1 1.3 1.0 0.6 1.1
Age started oral contraceptive pill 0.8 1.0 3.9 0.6 1.0 1.0 1.0 1.3 2.0 0.6 0.9 1.5 1.1 0.0 1.1 1.0 1.0 1.6 1.0 1.0 1.0 1.0 1.3 1.3 1.3 0.9 1.1 1.0 0.8 1.1 1.0 1.1 1.0 -0.8 1.1 0.7 1.2 0.9 0.8 0.6 1.0 0.1 1.0 1.2 0.5 1.0 0.6 0.8 1.4 1.2 -0.1 0.6
Diastolic blood pressure, automated reading 2.8 8.5 26.7 1.1 3.0 2.9 2.9 2.4 3.3 3.9 2.7 3.8 4.5 0.0 2.8 2.8 2.8 2.8 2.9 3.4 2.8 3.6 1.9 1.7 3.0 2.7 3.0 2.8 5.2 2.9 2.8 1.4 2.5 -3.6 3.1 2.5 3.0 1.8 1.8 2.6 2.1 2.6 1.0 1.3 3.4 2.7 4.4 3.4 4.3 2.4 -2.3 3.1
Ever depressed for a whole week 0.1 0.1 1.3 0.3 0.1 0.1 0.3 -0.0 0.8 0.1 0.1 0.1 0.8 0.0 0.2 0.1 0.2 -0.1 0.1 0.4 0.1 0.3 0.0 -0.1 0.3 0.2 0.2 0.1 0.1 0.2 0.1 1.1 0.1 -0.1 0.2 0.1 0.2 0.3 0.0 0.0 0.1 0.3 0.2 0.2 0.4 -0.1 0.0 0.3 0.1 -0.0 -0.2 0.0
Unable to work because of sickness or disability 0.3 0.4 4.9 -0.2 0.2 0.2 0.2 0.5 0.6 0.5 0.1 0.9 1.0 0.0 0.2 0.2 0.0 -0.5 0.1 0.9 0.2 0.0 0.0 -0.2 0.2 0.1 -0.1 0.2 0.7 0.2 0.2 0.6 0.3 0.1 0.3 0.8 -0.2 0.4 0.5 2.2 0.4 1.9 0.3 -0.1 0.8 -0.0 0.9 0.2 0.3 0.0 1.3 0.4
Commuting to job workplace: Cycle 0.2 0.2 1.9 -1.2 -0.0 -0.1 -0.3 -0.7 -0.1 0.0 -0.5 -0.7 -1.0 0.0 -0.1 -0.1 -0.2 -0.1 -0.2 -0.6 -0.1 -0.5 -0.3 -0.4 -0.5 -0.5 -0.4 -0.1 0.2 -0.3 -0.1 -1.4 -0.1 -0.1 -0.5 -0.2 -0.4 -0.5 -0.2 0.0 -0.3 -0.4 -0.6 -0.5 -0.3 -0.0 0.1 -0.4 0.2 -0.1 -0.5 -0.3
Myopia 0.2 0.3 1.9 0.5 -0.5 -0.4 -0.3 0.4 -0.5 0.3 0.4 -0.5 1.2 0.0 -0.6 -0.5 0.1 -0.2 -0.1 0.4 -0.5 1.4 -0.5 -0.6 -0.4 0.2 0.2 -0.5 0.4 0.1 -0.5 0.1 -0.5 0.2 0.8 -0.4 0.2 0.4 -0.7 -0.9 -0.1 0.6 0.0 0.2 0.4 -0.6 -0.2 0.8 -0.1 -0.6 -1.4 -0.1
Vascular/heart problems diagnosed by doctor 0.8 2.1 15.4 0.3 -0.6 -0.5 -0.7 -0.9 -2.1 -2.1 -1.2 -2.6 -3.9 0.0 -0.4 -0.4 -0.9 -0.8 -0.8 -1.9 -0.4 -2.9 -0.1 0.4 -0.8 -1.1 -1.1 -0.4 -3.3 -1.0 -0.5 -0.5 -0.3 1.2 -2.2 -0.8 -1.1 -1.0 0.3 -1.1 -0.6 -2.2 -0.1 -0.4 -1.8 -0.3 -2.2 -2.1 -2.1 -0.2 2.7 -1.0
Cholesterol lowering medication 0.5 0.8 4.7 -0.2 0.4 0.4 0.6 0.6 0.8 1.4 0.8 0.7 2.2 0.0 0.4 0.3 0.6 0.7 0.5 1.2 0.3 1.6 0.2 0.0 0.7 0.7 0.6 0.3 2.0 0.6 0.4 1.4 0.3 -0.1 1.2 0.6 0.5 0.9 0.1 1.2 0.5 1.8 0.4 0.4 1.3 0.3 1.1 1.2 1.1 0.2 -0.7 0.5
Medication: Omeprazole (e.g. Zanprol) 0.9 1.1 2.1 -1.1 -1.2 -1.2 -1.0 -1.4 -0.7 -1.4 -1.0 -0.6 -0.5 0.0 -1.1 -1.2 -1.1 -1.4 -1.1 -1.0 -1.2 -1.0 -1.1 -1.1 -0.9 -1.1 -1.1 -1.2 -1.3 -1.1 -1.2 0.2 -1.1 1.4 -1.0 -1.2 -1.2 -1.0 -1.0 -0.8 -1.0 -0.5 -0.8 -1.0 -1.1 -1.3 -1.3 -1.1 -1.5 -1.1 -0.1 -1.2
Pain experienced in last month 4.3 7.1 10.8 2.8 2.8 2.9 3.0 2.7 2.8 2.9 2.9 1.4 1.6 0.0 2.8 2.8 3.0 3.1 3.0 2.5 2.8 2.8 3.1 3.3 2.7 3.0 3.0 2.8 1.6 3.0 2.9 2.3 2.9 -2.8 2.6 2.8 3.0 2.7 2.9 1.3 2.9 1.5 3.1 3.2 2.0 3.1 1.9 2.6 2.5 2.8 2.3 2.7
Supplements: Calcium 0.2 0.2 1.6 0.5 0.1 0.2 0.4 -0.0 -0.4 0.1 0.4 0.3 0.3 0.0 0.2 0.1 0.4 0.1 0.3 0.3 0.2 0.4 0.3 0.3 0.4 0.5 0.4 0.2 -0.7 0.4 0.2 0.7 0.3 -0.0 0.4 0.2 0.3 0.7 0.4 0.0 0.6 0.5 1.0 0.8 0.2 0.2 -0.4 0.4 -0.5 0.2 1.2 0.2
Basal cell carcinoma (self-reported) 0.7 0.8 3.8 1.9 0.8 0.8 0.8 1.2 0.5 0.1 0.9 0.2 -0.2 0.0 0.8 0.8 0.9 -0.1 0.9 0.6 0.8 0.5 1.1 1.1 0.6 1.0 1.0 0.8 -0.7 1.0 0.8 0.3 0.9 -0.8 1.0 0.6 1.1 0.9 1.1 0.6 1.3 0.4 1.6 1.4 0.3 1.0 -0.1 0.6 0.1 1.1 1.7 0.8
Heart attack/myocardial infarction (self-reported) 0.9 1.2 2.5 -0.7 -1.5 -1.5 -1.4 -0.6 -0.9 -0.6 -0.6 0.3 0.6 0.0 -1.5 -1.5 -1.2 -1.2 -1.2 -0.8 -1.5 0.1 -1.4 -1.5 -1.3 -0.7 -1.0 -1.5 -0.4 -1.1 -1.5 -1.0 -1.5 1.5 -0.2 -1.0 -1.0 -0.4 -1.6 -1.1 -1.3 -0.2 -1.0 -0.8 -0.3 -1.6 -0.9 -0.3 -1.1 -1.6 -1.3 -1.0
Deep venous thrombosis (DVT) (self-reported) 0.4 0.6 1.7 0.2 0.9 0.8 1.0 0.9 1.3 1.0 0.4 1.0 0.0 0.0 0.9 0.9 0.6 1.0 0.7 0.3 0.9 0.1 1.0 0.7 0.8 0.5 0.6 0.9 0.6 0.6 0.9 0.8 0.8 -1.1 -0.1 0.4 0.7 -0.1 0.5 -0.5 0.4 -1.1 0.0 0.4 -0.3 1.0 0.7 -0.1 1.3 1.1 -0.6 0.6
Heart disease (siblings) 2.5 3.1 6.6 -0.7 -2.2 -2.2 -2.1 -1.0 -1.7 -2.1 -1.5 -1.9 -0.7 0.0 -2.2 -2.2 -1.9 -1.7 -2.0 -1.5 -2.2 -1.1 -2.0 -2.1 -1.9 -1.6 -1.7 -2.2 -2.0 -1.8 -2.2 -0.6 -2.1 2.6 -1.2 -2.2 -1.7 -1.2 -2.0 -1.7 -1.6 -0.7 -1.2 -1.3 -1.3 -2.1 -2.1 -1.3 -2.4 -1.9 -0.8 -1.8
Alcohol drinker status: Previous 0.2 0.3 0.8 0.5 0.5 0.6 0.5 0.8 0.4 0.4 0.4 0.3 0.0 0.0 0.5 0.5 0.5 0.6 0.5 0.0 0.5 0.5 0.4 0.6 0.3 0.4 0.5 0.5 0.6 0.5 0.5 -0.9 0.5 -0.4 0.5 0.8 0.5 0.9 0.6 0.6 0.3 0.3 0.4 0.4 0.9 0.5 0.4 0.7 0.5 0.2 0.4 0.2
Pack years of smoking 1.0 1.5 5.1 -1.6 -1.0 -1.0 -0.9 -0.9 -1.1 -1.6 -1.1 -0.9 -2.3 0.0 -1.0 -1.0 -1.1 -1.7 -1.1 -1.4 -1.0 -1.7 -0.6 -0.6 -1.3 -1.2 -1.3 -1.0 -1.7 -1.3 -1.0 -0.3 -0.9 0.9 -1.8 -1.1 -1.4 -1.5 -0.7 -1.3 -0.9 -1.4 -0.9 -0.9 -2.0 -0.9 -1.2 -1.8 -1.5 -0.6 0.5 -0.9
Impedance of whole body 0.5 2.5 9.2 -2.8 -1.1 -1.2 -1.4 -1.7 -0.8 -1.4 -1.8 -0.6 -2.2 0.0 -1.1 -1.1 -1.6 -1.1 -1.5 -1.1 -1.1 -2.8 -1.2 -0.9 -1.3 -1.8 -2.1 -1.1 -0.9 -2.0 -1.1 -2.0 -1.2 1.0 -3.0 -1.4 -2.3 -2.5 -0.9 -0.2 -1.2 -0.9 -2.0 -2.3 -2.3 -1.5 -0.7 -2.7 -1.2 -0.8 -0.1 -1.0
Leg fat mass (left) 0.3 1.1 3.6 1.0 1.0 1.1 1.2 1.4 -0.0 1.0 1.1 1.9 1.2 0.0 1.1 1.0 1.1 0.7 1.1 1.1 1.0 1.3 1.1 0.7 1.0 1.1 1.3 1.0 0.9 1.3 1.0 1.9 1.0 -1.1 1.2 0.6 1.5 0.5 0.7 0.0 1.0 -0.1 0.8 1.0 0.6 1.1 1.0 1.0 1.4 1.3 -0.8 1.0
Arm predicted mass (left) 0.5 2.6 4.2 1.8 1.7 1.7 1.7 1.2 0.5 1.7 1.5 1.0 1.0 0.0 1.7 1.7 1.8 0.5 1.8 1.4 1.7 1.6 1.9 1.8 1.7 1.6 1.8 1.7 0.8 1.9 1.7 1.7 1.8 -1.8 1.8 1.9 1.8 1.6 1.9 1.5 1.9 1.3 2.0 1.9 1.3 1.8 1.5 1.6 1.3 1.7 2.0 1.6