TWAS hub - DIP2B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1070	0.0330	1.3e-12	0.099	0.106	0.128	0.105	0.117	5.1e-12	7.9e-13	2.6e-15	9.9e-13	4.8e-14
2	GTEx	Adrenal Gland	0.1612	0.0730	9.8e-04	0.055	NA	0.053	NA	0.067	5.0e-03	NA	5.5e-03	NA	2.1e-03
3	GTEx	Brain Nucleus accumbens basal ganglia	0.3010	0.1390	8.0e-03	0.043	NA	0.064	NA	0.113	2.7e-02	NA	8.5e-03	NA	6.3e-04
4	GTEx	Cells Transformed fibroblasts	0.1650	0.0740	5.4e-05	0.081	NA	0.059	NA	0.085	1.2e-06	NA	3.3e-05	NA	6.2e-07
5	GTEx	Esophagus Mucosa	0.0790	0.0360	1.6e-03	0.030	NA	0.030	NA	0.021	4.0e-03	NA	4.0e-03	NA	1.3e-02
6	GTEx	Muscle Skeletal	0.0344	0.0168	2.2e-03	0.039	NA	0.031	NA	0.038	9.6e-05	NA	4.3e-04	NA	1.1e-04
7	GTEx	Stomach	0.0860	0.0430	6.2e-03	0.088	NA	0.009	NA	0.067	5.2e-05	NA	1.1e-01	NA	4.1e-04
8	GTEx	Testis	0.1390	0.0540	1.2e-04	0.083	NA	0.149	NA	0.150	1.6e-04	NA	3.8e-07	NA	3.7e-07
9	GTEx	Thyroid	0.0960	0.0310	1.0e-06	0.101	NA	0.105	NA	0.123	4.0e-08	NA	1.9e-08	NA	1.2e-09
10	GTEx	Whole Blood	0.1190	0.0480	2.5e-04	0.082	NA	0.071	NA	0.082	5.8e-08	NA	4.0e-07	NA	5.7e-08
11	METSIM	Adipose	0.0368	0.0191	3.8e-03	0.000	0.007	0.012	0.011	0.002	3.5e-01	2.6e-02	4.6e-03	8.0e-03	1.5e-01
12	YFS	Blood	0.3611	0.0629	0.0e+00	0.274	0.238	0.271	0.275	0.275	7.7e-90	9.4e-77	7.8e-89	2.8e-90	3.4e-90
13	TCGA	Bladder Urothelial Carcinoma	0.2160	0.0930	2.7e-06	0.055	0.049	0.062	NA	0.057	2.0e-05	5.3e-05	6.2e-06	NA	1.3e-05
14	TCGA	Breast Invasive Carcinoma	0.0169	0.0106	1.7e-03	0.016	0.011	0.003	NA	0.006	2.7e-04	1.7e-03	8.1e-02	NA	2.0e-02
15	TCGA	Colon Adenocarcinoma	0.1300	0.0600	8.8e-05	0.136	0.078	0.117	NA	0.123	3.0e-08	2.9e-05	2.8e-07	NA	1.3e-07
16	TCGA	Head and Neck Squamous Cell Carcinoma	0.0576	0.0391	6.4e-04	0.013	0.024	0.008	NA	0.010	1.1e-02	9.4e-04	3.8e-02	NA	2.1e-02
17	TCGA	Lung Adenocarcinoma	0.0862	0.0375	6.0e-05	0.019	0.050	0.051	NA	0.042	2.1e-03	1.5e-06	1.3e-06	NA	1.0e-05
18	TCGA	Testicular Germ Cell Tumors	0.1130	0.0640	8.6e-03	0.020	0.025	0.003	NA	0.019	6.6e-02	4.6e-02	2.5e-01	NA	6.8e-02
19	TCGA	Thyroid Carcinoma	0.1230	0.0420	1.1e-16	0.185	0.172	0.184	NA	0.185	1.1e-17	1.9e-16	1.3e-17	NA	9.2e-18

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Blood White Count	8.7	64.4	118.8	-10.1	10.9	-1.0	10.2	8.5	10.3	9.6	6.2	3.2	9.5	1.6	-9.5	5.4	5.1	9.5	7.3	9.1	10.5	2.2
Hair/balding pattern: Pattern 4	8.3	20.2	38.1	-6.2	5.8	-2.3	5.5	3.1	6.0	6.1	3.3	0.6	5.8	0.2	-6.2	2.5	2.2	5.2	4.3	4.8	5.7	0.1
Impedance of leg (left)	5.6	27.1	82.0	9.1	-5.9	4.2	-6.8	-2.4	-6.3	-6.5	-1.4	1.9	-6.5	1.3	7.1	-0.4	0.0	-6.6	-3.3	-7.2	-6.1	2.4
Heel bone mineral density (BMD) T-score, automated (right)	5.3	12.1	16.5	2.9	-3.8	2.7	-4.0	-3.4	-3.8	-4.0	-3.6	-2.9	-4.0	-2.3	3.8	-3.2	-3.6	-4.0	-4.1	-3.1	-3.8	-2.4
Impedance of leg (right)	5.2	25.1	79.6	8.9	-5.4	3.8	-6.5	-1.5	-5.9	-6.2	-0.9	2.3	-6.2	1.4	7.0	0.1	0.6	-6.3	-2.9	-7.1	-5.6	2.9
Ever had prostate specific antigen (PSA) test	5.2	6.0	9.8	-3.0	3.1	-1.9	3.1	2.8	2.6	2.9	1.7	0.9	2.9	0.9	-2.8	2.1	2.3	3.0	2.8	1.7	3.0	0.6
Impedance of whole body	5.1	25.8	74.4	8.6	-5.4	3.9	-6.7	-1.9	-6.1	-6.4	-1.7	1.4	-6.5	0.3	7.1	-0.9	-0.3	-6.6	-3.4	-7.3	-5.9	1.9
Blood Platelet Count	5.0	57.7	225.0	-15.0	9.3	-5.8	8.8	4.6	10.9	9.1	1.1	-3.3	8.9	-2.9	-9.3	2.3	0.3	8.7	5.0	7.5	9.0	-4.8
Lung FVC	5.0	25.3	48.0	-5.4	5.3	-4.2	6.5	2.8	5.5	6.7	3.9	0.8	6.7	1.3	-6.9	4.4	3.1	6.7	4.6	6.0	6.1	0.6
Heel T-Score	4.6	36.4	54.0	6.6	-6.8	3.9	-7.3	-6.3	-7.2	-7.1	-5.8	-3.6	-7.0	-3.2	7.0	-5.6	-4.8	-6.9	-5.9	-6.2	-7.2	-2.7
Medication: Ramipril	4.6	5.9	10.7	-1.0	2.0	-0.2	2.3	2.9	1.3	2.5	3.0	2.6	2.6	3.2	-2.3	3.3	3.3	2.6	3.0	1.4	1.7	2.4
Alcohol usually taken with meals	4.0	6.4	16.8	-4.1	2.8	-0.7	3.3	1.5	3.0	3.3	1.2	-0.4	3.3	1.0	-3.6	0.7	0.5	3.3	2.0	3.6	3.0	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	3.9	8.9	14.1	3.6	-3.7	2.2	-3.7	-3.3	-3.6	-3.7	-2.4	-1.5	-3.6	-1.3	3.6	-1.9	-2.2	-3.5	-3.2	-2.9	-3.4	-0.8
Pulse wave reflection index	3.9	4.8	11.1	0.2	-1.1	0.3	-1.7	-2.6	-1.8	-2.1	-2.9	-3.3	-2.0	-2.8	1.8	-2.6	-2.7	-2.0	-2.8	-1.6	-1.4	-2.8
Type 2 Diabetes (T2D) (2018)	3.7	6.9	13.5	-1.1	3.2	0.1	2.6	2.9	2.3	2.2	3.6	3.7	2.2	2.1	-1.9	2.6	3.2	2.1	2.6	2.5	2.9	3.5
Diabetes diagnosed by doctor	3.7	6.1	15.6	0.1	2.4	-0.3	1.9	3.5	1.6	1.5	3.3	4.0	1.5	2.8	-1.1	2.9	3.7	1.6	2.6	1.1	2.2	3.9
Medication: Co-codamol	3.6	4.2	7.4	-1.0	2.0	-0.9	2.1	1.9	2.1	1.9	2.7	2.7	1.8	2.5	-1.7	1.8	2.2	1.9	2.1	2.2	2.2	2.4
Medication: Metformin	3.6	5.0	10.8	-0.2	2.2	-0.4	2.0	3.0	1.7	1.7	2.9	3.3	1.8	2.1	-1.5	2.5	3.2	1.8	2.5	1.3	2.1	3.1
Relative age voice broke	3.6	5.6	10.1	-1.4	1.7	0.5	2.5	2.3	2.8	2.8	2.2	2.3	2.9	1.9	-2.6	2.1	2.2	3.2	2.9	2.9	2.2	1.7
Diabetes (self-reported)	3.6	5.5	13.2	-0.5	2.4	-0.4	2.1	3.2	1.9	1.7	3.1	3.6	1.7	2.4	-1.3	2.6	3.3	1.7	2.5	1.4	2.2	3.3
Impedance of arm (right)	3.6	17.0	50.3	7.1	-3.8	3.3	-5.6	-0.9	-4.7	-5.3	-1.2	1.5	-5.3	-0.5	6.0	-0.5	0.1	-5.5	-2.5	-6.1	-4.4	1.9
Schizophrenia vs Biploar Disorder	3.5	4.6	13.8	3.1	-1.8	3.7	-2.3	-2.1	-2.8	-2.5	-1.0	-0.5	-2.5	-1.1	2.5	-0.9	-1.2	-2.5	-2.3	-1.5	-2.1	0.0
Qualifications: None of the above	3.5	7.6	18.0	1.4	-2.9	0.0	-3.0	-2.1	-2.6	-2.9	-3.4	-2.9	-2.9	-2.6	2.8	-1.9	-2.3	-3.0	-2.4	-4.2	-3.3	-2.9
Financial difficulties in last 2 years	3.4	4.5	11.0	1.8	-2.3	0.4	-2.1	-2.1	-3.3	-2.5	-2.2	-2.3	-2.3	-0.5	2.1	-1.6	-2.0	-2.2	-2.9	-1.9	-2.3	-1.5
Hearing aid user	3.4	3.8	8.0	0.9	-2.4	-0.2	-2.4	-1.3	-1.9	-1.7	-2.6	-2.8	-1.7	-0.9	1.5	-1.5	-2.0	-1.9	-1.9	-2.4	-2.2	-2.5
Medication: Atorvastatin	3.4	4.2	8.4	-1.4	2.3	0.1	2.9	1.3	1.3	2.4	2.5	1.4	2.5	1.6	-2.5	1.9	1.8	2.5	1.9	2.6	2.4	1.5
Diastolic blood pressure, automated reading	3.1	9.6	39.4	6.3	-3.2	1.3	-3.0	-2.9	-5.9	-3.1	0.5	1.1	-2.9	2.5	3.0	1.0	0.8	-3.0	-2.5	-2.9	-3.2	2.7
Schizophrenia (2014)	3.0	6.7	15.5	3.7	-2.2	1.6	-3.4	0.1	-3.2	-3.5	-0.9	0.5	-3.6	0.3	3.9	-0.7	-0.3	-3.7	-2.2	-3.9	-2.6	0.8
High cholesterol (Self-reported)	3.0	5.4	10.1	-1.5	1.9	-0.1	3.2	1.7	1.6	2.5	2.8	1.8	2.6	3.1	-2.5	2.5	2.3	2.8	2.4	2.8	2.3	1.8
Crohns Disease (2012)	2.9	4.6	9.3	-2.9	3.1	-1.1	2.9	2.2	2.5	2.6	1.4	0.3	2.6	-0.1	-2.7	0.8	1.0	2.7	2.0	2.4	2.9	-0.0
Hair/balding pattern: Pattern 3	2.9	4.3	12.0	-3.2	1.9	-3.5	2.5	0.7	2.7	2.3	-0.4	-1.7	2.3	-1.6	-2.4	-0.0	-0.0	2.5	1.5	1.4	2.2	-2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.9	6.1	11.9	-2.6	3.0	-1.7	3.0	1.3	3.5	3.1	2.0	1.1	3.0	0.2	-3.1	1.4	1.6	3.0	2.6	3.0	3.3	0.8
Trunk fat percentage	2.8	11.4	23.6	4.9	-3.5	3.3	-4.5	-1.5	-4.5	-4.5	-1.4	0.8	-4.5	0.6	4.8	-1.5	-0.7	-4.2	-3.0	-3.8	-3.8	1.4
Father’s age at death	2.8	3.7	6.0	0.9	-2.5	0.7	-2.4	-1.5	-1.9	-1.8	-2.4	-2.1	-1.9	-1.5	1.7	-1.6	-2.0	-2.0	-1.7	-2.5	-2.3	-2.1
Pulse wave Arterial Stiffness index	2.8	3.3	5.6	1.5	-1.5	1.2	-2.0	-1.9	-2.1	-2.4	-1.8	-1.2	-2.3	-1.3	2.3	-1.7	-1.5	-2.2	-2.1	-1.7	-1.8	-0.9
Impedance of arm (left)	2.8	13.1	40.8	6.4	-3.3	2.8	-4.9	-0.5	-4.3	-4.6	-1.0	1.4	-4.6	-0.2	5.2	-0.4	0.2	-4.8	-2.2	-5.5	-3.9	1.7
Average weekly beer plus cider intake	2.8	4.0	8.3	2.9	-2.8	1.1	-2.7	-0.5	-2.5	-2.6	-1.0	0.1	-2.6	1.1	2.7	-0.4	-0.5	-2.5	-1.4	-2.6	-2.6	0.4
Reason for reducing amount of alcohol drunk: Health precaution	2.7	3.1	8.9	3.0	-2.0	0.2	-2.4	-0.9	-2.6	-2.0	-0.7	0.0	-2.1	-0.3	2.2	-0.1	-0.1	-2.3	-1.3	-2.8	-2.0	0.5
Alcohol drinker status: Previous	2.7	3.1	6.3	1.5	-1.8	1.5	-2.3	-0.5	-1.6	-2.1	-1.9	-1.0	-2.1	-1.8	2.3	-1.3	-1.3	-2.0	-1.4	-2.5	-2.1	-1.2
Current tobacco smoking	2.6	4.3	10.3	-2.4	2.5	-0.1	3.2	0.9	1.9	2.8	1.4	-0.4	2.8	0.0	-3.2	1.4	1.0	2.8	2.0	2.3	2.8	-0.3
Hypothyroidism (self reported)	2.5	5.8	12.7	0.2	2.8	1.0	2.2	2.7	1.5	1.9	3.3	3.2	1.9	2.3	-1.8	2.4	3.3	2.0	2.5	2.0	2.6	3.6
Qualifications: nursing, teaching	2.5	3.9	6.3	-2.3	2.5	-2.3	2.2	2.5	2.2	2.4	1.1	0.1	2.5	0.1	-2.5	1.2	1.3	2.5	1.9	1.6	2.5	0.2
Bipolar Disorder or Schizophrenia	2.4	5.9	16.7	3.4	-2.4	0.8	-3.1	1.4	-2.7	-3.0	-0.4	1.4	-3.0	1.9	3.5	0.2	0.7	-3.1	-1.3	-4.1	-2.6	1.5
Schizophrenia (2018)	2.4	4.9	12.4	3.5	-1.8	1.6	-2.9	0.3	-2.7	-2.9	-0.5	0.8	-2.9	0.6	3.3	-0.2	0.1	-3.1	-1.6	-3.5	-2.3	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.4	2.9	6.3	0.1	-1.1	0.6	-1.9	-0.9	-1.3	-1.5	-2.4	-2.5	-1.5	-1.9	1.3	-2.5	-2.3	-1.5	-2.1	-1.1	-1.3	-2.2
Systolic Blood Pressure	2.3	11.6	49.4	7.0	-2.4	1.7	-1.7	-0.6	-5.6	-2.1	2.8	3.8	-1.8	5.1	2.3	2.9	3.6	-1.7	0.0	-2.5	-2.5	5.4
Hand grip strength (left)	2.3	6.1	14.1	-1.2	1.5	-2.3	2.8	1.4	2.2	2.9	2.9	2.1	2.9	2.8	-3.0	2.1	1.9	3.0	2.2	3.8	2.3	2.0
Maternal smoking around birth	2.3	3.4	10.4	-0.6	-1.2	-1.0	-0.9	-2.3	-0.9	-1.0	-2.6	-3.0	-0.9	-2.5	0.7	-2.2	-2.9	-0.5	-2.0	-0.1	-1.4	-3.2
Medication: Amlodipine	2.2	3.1	8.7	3.0	-1.1	0.9	-1.5	1.1	-2.7	-2.1	0.3	1.4	-1.9	1.4	2.3	0.9	1.5	-1.7	-0.5	-2.9	-1.2	2.0
Smoking status: Current	2.2	3.5	8.9	-2.3	2.1	-0.4	2.9	0.5	1.8	2.6	1.1	-0.7	2.6	-0.5	-3.0	1.1	0.6	2.5	1.6	2.1	2.4	-0.7
Ever had hysterectomy (womb removed)	2.1	2.3	5.3	2.3	-2.0	0.0	-2.1	-1.9	-1.5	-1.7	-1.4	-0.3	-1.7	-0.9	1.9	-1.1	-1.0	-1.5	-1.5	-1.3	-2.1	-0.3
Body fat percentage	2.1	8.4	16.6	4.0	-3.0	3.2	-3.8	-1.4	-3.9	-4.0	-1.3	0.6	-3.8	0.7	4.1	-1.5	-0.7	-3.6	-2.8	-3.0	-3.3	1.2
Mother’s age at death	2.1	2.7	7.6	2.5	-2.8	0.5	-2.4	-1.2	-2.2	-2.0	-1.1	-0.2	-1.9	0.4	1.9	-0.6	-0.7	-1.6	-1.4	-1.4	-2.2	0.1
Mouth/teeth dental problems: Mouth ulcers	2.0	3.2	9.2	-3.0	1.0	-2.8	1.8	-0.7	2.0	2.2	-0.3	-1.6	2.2	-1.7	-2.4	0.1	-0.4	2.1	1.0	1.8	1.7	-1.7
Medication for hormone replacement therapy	1.9	2.1	6.3	-0.5	-1.1	-0.4	-1.2	-1.1	-1.3	-1.1	-2.2	-2.5	-1.1	-1.0	0.9	-1.7	-2.1	-0.9	-1.7	-1.0	-1.3	-2.3
Bilateral oophorectomy (both ovaries removed)	1.9	2.1	6.1	1.7	-2.5	0.4	-2.0	-1.0	-1.9	-1.8	-1.1	-0.3	-1.8	0.5	2.0	-0.5	-0.5	-1.6	-1.1	-1.9	-1.9	-0.1
Medication: Atenolol	1.9	2.4	5.4	0.9	-2.2	0.6	-1.4	-1.0	-2.3	-1.6	-1.9	-1.7	-1.4	0.6	1.3	-1.0	-1.5	-1.1	-1.7	-1.4	-2.3	-1.6
Medication: Lansoprazole	1.9	2.2	8.1	-1.3	1.4	-0.3	1.2	2.8	2.0	1.0	1.6	1.8	1.0	1.3	-0.7	1.0	1.6	1.3	1.7	0.8	1.7	1.5
Prospective memory result	1.9	2.3	3.9	-0.7	1.6	-1.8	1.5	0.8	1.2	1.4	1.8	1.2	1.5	1.0	-1.5	2.0	2.0	1.7	1.8	0.8	2.0	1.4
Hypothyroidism/myxoedema (self-reported)	1.9	3.8	6.5	-0.4	2.5	0.9	1.9	2.3	1.7	1.7	2.4	2.2	1.7	1.1	-1.6	1.7	2.4	1.8	1.9	1.9	2.5	2.5
Pulse wave peak to peak time	1.9	2.2	3.5	-0.9	1.0	-1.0	1.5	1.4	1.7	1.9	1.6	1.4	1.9	1.2	-1.8	1.6	1.5	1.8	1.9	1.3	1.3	1.1
Supplements: Calcium	1.9	2.1	5.2	2.3	-1.2	1.4	-1.9	-1.1	-1.6	-1.6	-0.9	-0.1	-1.6	-1.4	1.7	-1.4	-1.0	-1.7	-1.6	-1.2	-1.7	-0.1
HbA1C	1.8	2.0	5.1	-2.2	2.0	0.2	2.1	2.2	1.7	1.2	0.9	0.2	1.2	-0.3	-1.3	0.3	0.7	1.4	1.4	1.8	1.7	-0.2
Primary Biliary Cirrhosis	1.8	2.6	6.1	1.7	-1.4	1.8	-2.2	0.5	-1.2	-1.9	-1.4	-0.4	-2.0	-0.0	2.2	-1.8	-0.8	-2.2	-1.3	-2.5	-1.9	-0.3
High blood pressure	1.8	4.9	18.0	3.8	-1.4	0.7	-0.8	1.0	-3.9	-1.0	2.2	1.8	-0.8	4.2	0.9	3.1	2.7	-0.7	-0.0	-1.7	-1.2	3.1
Sitting height	1.8	13.1	42.6	6.5	-5.1	-0.7	-4.5	-4.2	-5.3	-4.0	-0.0	1.7	-3.9	1.9	4.1	0.4	-0.0	-3.9	-2.8	-3.3	-4.4	2.5
Trunk fat mass	1.8	7.7	17.2	4.1	-3.0	2.7	-3.7	-1.7	-3.8	-3.7	-0.8	1.1	-3.6	0.9	3.8	-1.1	-0.5	-3.4	-2.5	-2.7	-3.2	1.6
Hayfever/allergic rhinitis (self-reported)	1.8	2.4	5.4	-0.1	1.4	-0.8	1.7	1.2	1.4	1.5	2.3	1.8	1.5	1.2	-1.3	1.9	2.0	1.4	1.5	1.3	1.9	2.1
Falls in the last year	1.8	2.4	5.1	-0.9	1.8	-0.5	1.9	2.0	1.8	1.6	0.9	1.4	1.7	-0.3	-1.5	1.0	1.7	2.3	1.9	1.7	1.9	1.1
Hypertension (Self-reported)	1.8	5.0	17.9	4.2	-1.5	1.0	-1.1	0.9	-4.1	-1.5	1.8	1.7	-1.2	3.7	1.4	2.7	2.4	-1.1	-0.4	-2.1	-1.4	3.0
Intelligence (Savage-Jansen 2018)	1.7	5.1	9.0	-1.6	2.4	1.0	3.0	2.2	1.8	2.7	2.4	1.1	2.8	1.7	-2.8	2.2	1.9	2.9	2.3	2.9	2.6	1.2
Hearing difficulty/problems: Yes	1.7	2.6	5.5	0.9	-1.7	-0.6	-1.9	-0.8	-1.5	-1.6	-2.3	-2.2	-1.5	-1.3	1.6	-1.2	-1.4	-1.3	-1.3	-2.3	-1.7	-2.0
Systolic blood pressure, automated reading	1.7	5.1	24.6	5.0	-1.9	0.4	-1.8	-1.5	-3.9	-2.1	0.9	1.9	-2.0	2.1	2.2	1.3	1.5	-1.8	-1.2	-1.9	-2.1	2.9
Handedness (chirality/laterality): Left-handed	1.7	2.0	3.7	0.1	-1.8	0.2	-1.5	-0.9	-1.3	-1.4	-1.7	-1.7	-1.4	-0.5	1.3	-1.6	-1.9	-1.6	-1.8	-1.1	-1.6	-1.6
Alcohol drinker status: Never	1.7	2.0	3.5	-0.9	1.0	-1.2	1.9	0.4	1.2	1.6	1.6	1.2	1.7	1.7	-1.6	1.5	1.2	1.7	1.6	1.8	1.2	0.9
Serious illness, injury or assault of a close relative in last 2 years	1.6	1.9	4.3	-2.1	1.3	-1.5	1.7	1.6	1.4	1.6	1.2	-0.1	1.6	0.7	-1.6	1.5	1.0	1.4	1.6	0.3	1.6	-0.3
Medication: Cholesterol lowering	1.6	2.4	5.6	-1.8	2.4	0.1	2.1	0.8	1.5	1.9	1.6	0.6	1.9	1.1	-2.0	1.1	1.0	1.9	1.5	1.9	1.8	0.4
Qualifications: College or University degree	1.6	5.1	10.4	-2.0	2.3	-1.9	2.5	2.1	3.2	2.8	2.2	1.5	2.6	1.3	-2.5	2.0	1.9	2.4	2.3	2.3	2.8	1.3
Chest pain or discomfort	1.6	2.3	5.8	-0.6	1.0	0.8	1.7	0.7	0.8	1.9	1.9	0.7	1.9	2.0	-1.9	2.4	1.6	1.8	1.9	0.9	1.4	0.8
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	4.3	-1.6	1.8	-0.7	2.0	0.7	0.5	1.7	1.0	-0.2	1.7	-0.2	-2.1	0.7	0.6	1.6	1.0	1.7	1.7	0.1
Medication: Aspirin	1.6	2.1	4.4	-1.2	1.7	-0.6	2.0	1.5	0.6	1.6	1.4	0.4	1.8	0.6	-1.8	1.9	1.4	2.1	1.5	1.3	1.6	0.5
Guilty feelings	1.6	2.4	5.5	-0.8	2.1	0.1	1.4	2.3	2.1	1.5	1.8	1.5	1.4	1.1	-1.3	1.5	1.8	1.0	1.8	0.5	2.0	1.3
Bipolar Disorder (2011)	1.5	1.4	6.7	1.2	-0.6	0.5	-0.5	2.6	-0.4	-0.4	0.8	1.8	-0.5	2.1	0.8	1.2	1.4	-0.7	0.5	-1.4	-0.5	1.6
Ulcerative Colitis	1.5	2.1	3.6	-1.9	1.2	-1.0	1.7	1.7	1.1	1.9	1.1	0.5	1.9	1.2	-1.9	1.6	1.5	1.8	1.9	0.6	1.4	0.3
Height	1.5	28.7	114.1	10.7	-6.8	2.6	-6.4	-4.9	-7.4	-5.9	0.4	3.4	-5.8	2.8	6.3	-0.3	0.5	-5.9	-2.4	-5.4	-6.5	4.1
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	4.1	-1.5	2.0	0.4	1.5	-0.0	1.5	1.3	1.2	0.5	1.3	1.1	-1.4	0.5	0.8	1.3	0.9	1.9	2.0	0.8
Qualifications: A levels/AS levels or equivalent	1.5	3.4	6.4	-2.0	1.5	0.1	2.4	1.0	2.2	2.5	1.7	0.5	2.5	1.4	-2.5	1.4	0.9	2.3	1.8	2.4	2.1	0.4
Standing height	1.5	14.9	61.3	7.8	-4.6	1.3	-4.7	-3.9	-4.5	-4.2	0.5	3.3	-4.2	1.5	4.8	0.6	0.6	-4.3	-2.2	-3.6	-4.4	3.5
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.2	12.4	3.5	-1.9	2.0	-1.7	-0.5	-1.9	-1.6	1.1	2.1	-1.6	1.9	1.9	0.9	0.7	-1.9	-0.6	-1.7	-1.8	2.0
Leg fat percentage (left)	1.5	5.5	10.2	2.9	-2.8	2.8	-2.9	-1.6	-3.2	-3.1	-1.3	0.2	-3.0	0.8	3.1	-1.5	-0.9	-2.7	-2.4	-1.9	-2.7	0.7
Severe depression (siblings)	1.4	1.5	5.2	-0.8	1.0	-0.9	1.3	2.3	1.1	1.2	1.3	1.4	1.1	1.2	-1.0	1.6	1.5	0.9	1.4	0.3	0.9	1.1
Hearing difficulty/problems with background noise	1.4	2.3	4.2	-0.2	1.1	0.2	1.7	1.2	0.9	1.6	1.7	1.3	1.7	2.0	-1.6	2.0	1.8	1.9	1.9	1.3	1.3	1.3
Allergy	1.4	3.1	6.9	-0.1	-1.6	1.1	-1.4	-1.9	-1.6	-1.7	-2.2	-2.1	-1.7	-1.3	1.3	-2.6	-2.6	-1.6	-2.4	-0.4	-1.7	-2.1
Headache pain in last month	1.4	2.4	4.6	-0.0	1.4	0.4	2.1	1.2	0.5	1.9	2.0	0.9	1.9	1.4	-2.1	2.0	1.6	1.8	1.6	1.4	1.5	1.2
High blood pressure (siblings)	1.4	2.0	6.7	2.6	-1.9	-0.7	-1.1	0.6	-2.3	-1.1	0.3	0.4	-0.9	2.1	1.1	1.8	1.4	-0.6	-0.2	-2.0	-1.2	1.2
Comparative body size at age 10	1.4	3.9	14.6	-3.8	2.3	-0.5	1.9	0.1	2.7	2.0	-0.5	-1.9	1.8	-2.1	-2.4	-1.4	-1.7	1.3	0.0	2.5	1.9	-2.3
Health satisfaction	1.4	1.8	9.1	-1.5	0.8	0.8	0.4	-0.5	0.2	-0.1	-1.4	-2.4	-0.3	-3.0	0.1	-1.7	-1.8	-0.5	-1.2	-0.0	0.5	-2.3
Mouth/teeth dental problems: Loose teeth	1.4	1.7	4.6	-1.1	1.5	0.5	1.4	2.1	1.1	1.5	1.1	0.6	1.6	0.9	-1.6	0.5	1.2	1.6	1.3	1.2	1.6	0.8
Family relationship satisfaction	1.4	1.7	3.6	-0.5	1.8	-0.4	1.6	1.9	0.9	1.3	1.6	0.8	1.3	0.4	-1.3	1.4	1.5	1.3	1.1	1.3	1.8	1.3
Medication: Aspirin	1.4	1.8	4.1	-1.0	1.4	-0.8	1.9	1.2	0.3	1.5	1.5	0.5	1.6	0.8	-1.7	2.0	1.4	1.9	1.4	1.2	1.4	0.6
Smoking status: Previous	1.4	2.0	6.3	1.7	-1.9	0.3	-2.0	0.6	-2.0	-1.6	-0.7	-0.1	-1.6	0.9	1.7	0.3	-0.0	-1.6	-0.8	-2.5	-2.0	-0.0
Medication: Blood pressure	1.4	2.7	10.9	2.9	-1.6	0.3	-0.7	0.4	-3.3	-1.2	0.9	0.9	-1.0	2.6	1.1	2.1	1.6	-0.8	-0.4	-1.8	-1.3	1.8
Allergy or Eczema	1.3	3.4	8.6	1.2	1.5	-1.4	1.1	2.1	1.2	1.2	2.7	2.8	1.2	1.2	-0.9	2.6	2.9	1.2	2.2	0.3	1.7	2.9
Ever used hormone-replacement therapy (HRT)	1.3	1.6	3.0	-0.1	-1.6	-0.7	-1.5	-1.2	-1.6	-1.4	-1.7	-1.5	-1.3	-0.1	1.2	-1.5	-1.4	-1.0	-1.5	-0.9	-1.3	-1.1
Hand grip strength (right)	1.3	3.5	7.5	-0.2	0.9	-1.6	1.9	1.3	1.3	1.8	2.5	2.2	1.9	2.7	-1.8	2.3	1.8	2.0	1.8	2.3	1.5	2.0
Illnesses of siblings	1.3	1.9	5.0	-2.2	2.0	0.5	1.5	-0.2	1.9	1.6	0.5	-0.3	1.5	-0.6	-1.9	-0.7	-0.7	1.2	0.7	2.2	1.5	-0.8
Number of live births	1.3	1.9	8.5	1.0	-0.3	2.9	-1.2	-0.7	-1.2	-1.5	-1.1	-0.8	-1.5	-1.7	1.4	-1.5	-1.5	-1.5	-1.7	-0.8	-1.0	-0.8
Mouth/teeth dental problems: Dentures	1.3	2.1	6.5	-0.3	-1.1	1.0	-1.2	-1.5	-0.8	-1.0	-2.0	-2.3	-1.0	-1.7	0.8	-1.4	-1.9	-1.1	-1.2	-1.5	-1.4	-2.5
Leg fat percentage (right)	1.3	4.6	9.3	2.8	-2.4	2.7	-2.8	-0.9	-2.9	-3.0	-0.9	0.5	-2.8	0.9	3.0	-1.2	-0.5	-2.5	-2.1	-1.9	-2.3	1.0
Medication for pain relief, constipation, heartburn	1.3	2.1	4.2	0.9	-1.9	-0.4	-1.8	-1.9	-0.8	-1.6	-1.5	-0.9	-1.7	-1.1	1.6	-2.1	-1.8	-1.8	-1.7	-0.6	-1.4	-0.8
Medication: Blood pressure	1.3	2.3	8.1	2.3	-0.7	0.7	-0.5	1.4	-2.0	-0.5	1.5	2.0	-0.4	2.8	0.6	2.2	1.9	-0.3	0.5	-1.0	-0.9	2.3
Medication: Ibuprofen	1.3	1.6	6.7	-0.1	0.3	-0.8	0.6	2.6	0.7	1.0	1.2	1.5	1.0	2.0	-0.8	1.9	1.7	1.0	1.7	-0.2	0.2	1.0
Ever had bowel cancer screening	1.3	1.5	4.1	-0.5	-0.6	-0.8	-0.6	-1.0	-1.1	-1.0	-1.8	-2.0	-1.0	-1.5	0.7	-1.3	-1.8	-0.9	-1.5	-0.5	-1.0	-2.0
Medication: Bendroflumethiazide	1.3	2.0	6.7	0.8	0.4	-1.3	1.1	2.5	-1.6	0.7	1.5	0.3	0.9	2.4	-1.0	2.6	2.0	1.0	1.0	-0.5	0.5	1.1
Vascular/heart problems diagnosed by doctor	1.3	3.4	14.6	-3.0	1.2	-0.8	0.3	-0.3	3.5	0.5	-1.8	-1.1	0.3	-3.8	-0.3	-3.0	-2.3	0.2	-0.2	1.3	1.0	-2.3
Prostate Cancer	1.2	1.7	9.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.7	3.0	2.2	3.0	2.7	-0.4
Blood Red Count	1.2	11.6	19.2	3.7	-4.0	1.7	-4.1	-4.0	-4.4	-4.2	-2.9	-1.7	-4.1	-1.8	3.9	-3.7	-2.7	-3.9	-3.9	-2.5	-3.6	-0.6
Number of treatments/medications taken	1.2	2.2	7.0	1.1	1.0	0.6	0.9	2.4	-0.9	0.2	1.8	1.8	0.4	2.1	-0.1	2.4	2.6	0.6	1.2	-0.8	0.6	2.1
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.9	9.3	0.3	1.8	-0.2	1.8	0.4	2.0	1.8	3.1	3.0	1.7	1.9	-1.6	1.8	2.0	1.6	1.8	2.6	2.1	2.8
Birth weight of first child	1.2	2.2	5.9	-2.4	1.3	0.2	0.9	-1.3	1.6	1.2	-0.7	-1.9	1.1	-2.4	-1.5	-1.7	-1.7	0.8	-0.3	2.0	1.2	-2.0
Peak expiratory flow (PEF)	1.2	2.7	9.3	1.4	0.1	-0.6	0.6	-0.5	0.4	0.8	2.8	2.8	0.7	3.0	-0.5	2.0	1.9	0.7	1.0	1.6	0.7	3.0
Whole body fat mass	1.2	4.9	9.6	3.1	-2.4	2.3	-2.9	-1.5	-3.0	-3.0	-0.7	0.9	-2.9	0.9	3.1	-1.2	-0.5	-2.7	-2.2	-1.7	-2.5	1.4
Illnesses of father: High blood pressure	1.2	1.5	5.9	2.4	-2.0	0.6	-1.3	-0.6	-2.1	-1.3	-0.5	0.1	-1.1	-0.1	1.4	0.4	0.1	-1.0	-0.7	-1.4	-1.7	0.4
Bipolar Disorder (2018)	1.1	1.8	5.3	1.1	-1.5	-0.7	-1.4	2.1	-1.1	-1.2	-0.0	1.2	-1.2	2.3	1.5	0.6	1.1	-1.2	-0.1	-2.1	-1.3	1.2
Crohns Disease (2017)	1.1	2.5	6.8	-2.6	2.5	0.2	1.8	1.2	2.0	1.8	0.2	-0.8	1.7	-2.0	-1.9	-0.3	-0.1	1.6	1.0	1.4	2.0	-1.0
Lupus	1.1	1.6	6.1	2.5	-0.9	1.4	-1.5	-0.4	-0.6	-1.4	0.2	1.7	-1.4	0.1	1.8	-0.6	0.7	-1.4	0.0	-1.3	-1.1	1.8
Triglycerides	1.1	1.9	4.9	-1.4	2.2	-0.3	1.5	1.8	1.8	1.5	1.1	0.7	1.4	-0.2	-1.2	1.0	1.5	1.3	1.5	0.7	2.2	0.8
Relative age of first facial hair	1.1	2.4	6.5	-1.2	1.1	-1.0	1.5	2.2	1.9	2.0	0.8	0.2	2.0	0.1	-1.8	2.1	1.6	1.9	2.5	-0.3	1.2	-0.3
Age when periods started (menarche)	1.1	2.7	4.3	1.2	-1.0	1.4	-1.4	-1.5	-1.4	-2.1	-1.8	-1.3	-2.0	-1.7	2.1	-1.5	-1.9	-1.8	-1.8	-1.6	-1.7	-1.6
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.6	0.3	-0.8	0.5	-1.4	-0.5	-0.7	-1.2	-1.6	-1.4	-1.2	-1.6	1.2	-1.4	-1.2	-1.2	-1.1	-1.5	-1.0	-1.3
Forced vital capacity (FVC), Best measure	1.1	3.9	10.3	1.0	1.6	-0.5	1.5	0.4	1.5	1.7	3.2	3.2	1.7	1.9	-1.4	2.4	2.5	1.5	2.1	1.8	1.8	3.1
Emphysema/chronic bronchitis	1.1	1.2	2.7	-1.5	0.9	-0.6	1.2	-0.6	1.5	1.5	0.7	0.0	1.5	0.2	-1.5	0.9	0.2	1.5	1.2	1.6	1.0	-0.3
Neck or shoulder pain in last month	1.1	1.6	4.4	-0.2	0.6	-0.4	1.0	1.6	1.3	1.1	1.5	1.7	1.1	2.1	-0.8	1.5	1.7	1.2	1.6	0.7	0.8	1.3
Number of full sisters	1.1	1.3	4.2	0.2	0.8	0.1	1.4	0.5	1.0	1.0	1.5	1.8	1.0	1.5	-1.0	0.5	0.8	1.0	0.9	2.1	0.9	1.5
Had major operations	1.1	1.3	3.9	-0.4	0.9	-0.5	1.2	1.0	0.5	0.9	2.0	1.7	0.9	1.6	-0.9	1.5	1.1	0.5	0.9	1.0	1.0	1.6
Medication for cholesterol	1.1	1.7	7.8	-1.4	1.7	-0.5	1.1	-0.0	2.8	1.7	0.6	0.6	1.5	-1.3	-1.6	-0.1	0.1	1.2	1.4	1.6	1.4	-0.2
Medication: Paracetamol	1.1	1.7	4.5	1.4	0.9	1.3	0.8	1.4	-0.6	0.7	1.8	1.7	0.7	1.4	-0.7	2.0	2.1	0.6	0.9	-0.2	0.6	2.1
Major Depression (MDD)	1.0	1.3	4.5	0.9	-0.9	2.1	-1.3	-1.2	-0.9	-1.0	-1.1	-1.1	-0.9	-1.4	1.0	-1.0	-1.1	-0.8	-1.2	-0.7	-1.0	-1.1
Verbal and Numeric Reasoning (VNR)	1.0	2.5	6.0	-1.2	1.4	1.0	1.9	1.1	1.1	1.8	1.8	1.2	1.9	1.5	-1.8	1.4	1.3	2.0	1.5	2.4	1.8	1.3
HDL Cholesterol	1.0	1.6	5.8	-0.5	1.5	0.7	1.5	0.2	1.5	1.0	1.1	1.3	1.2	0.4	-1.1	0.7	1.1	1.7	1.3	2.4	1.6	1.4
Hayfever, allergic rhinitis or eczema	1.0	2.3	5.3	1.0	1.0	-2.0	0.8	1.4	1.1	1.2	2.1	2.0	1.1	1.0	-0.8	2.3	2.2	1.0	1.8	0.1	1.3	2.2
Lung cancer (father)	1.0	1.2	2.9	-0.1	1.4	0.6	1.2	1.7	0.4	1.1	1.2	1.2	1.1	0.7	-1.0	1.4	1.6	0.8	1.4	-0.1	0.7	1.0
Gout (self-reported)	1.0	1.4	4.8	2.2	-0.7	1.7	-1.3	-1.4	-1.4	-1.4	-0.1	0.7	-1.4	-0.5	1.5	-0.2	0.3	-1.4	-0.9	-1.3	-0.7	1.2
Leg pain on walking	1.0	1.3	3.3	-1.8	1.2	0.1	1.2	0.2	1.7	1.0	-0.6	-1.2	1.1	-1.7	-1.0	-0.2	-0.1	1.5	0.8	0.7	1.4	-1.3
Osteoarthritis (self-reported)	1.0	1.3	4.3	-1.6	1.5	0.6	1.4	-0.5	2.1	1.0	0.5	0.7	1.0	-0.7	-0.9	-0.1	0.4	1.3	1.0	1.8	1.6	0.3
Fractured/broken bones in last 5 years	1.0	1.3	3.5	-0.3	0.9	-0.6	1.3	1.1	0.5	0.9	1.6	1.1	1.0	1.6	-0.9	1.9	1.4	1.0	1.4	0.6	0.9	1.0
Reaction Time	0.9	1.7	5.2	1.2	-0.4	2.3	-1.5	-1.4	-1.1	-1.3	-1.4	-0.5	-1.3	-1.5	1.4	-1.5	-0.8	-1.4	-1.1	-1.5	-1.3	-0.5
Age at First Birth	0.9	1.3	4.2	0.2	0.5	-1.6	0.3	1.4	0.3	0.6	1.5	1.7	0.6	1.2	-0.5	1.4	1.8	0.6	1.3	0.2	0.8	2.0
Fasting Glucose	0.9	1.0	5.2	-0.7	0.6	-2.3	1.1	1.1	1.2	1.2	0.5	0.2	1.1	1.2	-0.9	0.8	0.8	0.9	1.4	0.7	0.4	-0.1
LDL Cholesterol	0.9	1.4	4.1	-2.0	1.0	-2.0	1.1	-0.6	1.1	0.9	-0.7	-1.4	1.0	-1.4	-1.1	-0.5	-0.5	1.5	0.4	1.2	0.8	-1.7
Blood Eosinophil Count	0.9	6.7	32.1	-5.7	3.7	-0.3	2.3	1.5	3.3	2.0	-1.1	-2.5	1.9	-3.3	-2.2	-1.1	-1.7	1.9	-0.5	2.6	2.7	-3.0
Average weekly fortified wine intake	0.9	1.1	2.3	-1.5	1.4	-1.5	1.3	1.2	1.0	1.1	0.6	-0.4	1.1	-0.1	-1.2	0.9	0.8	1.0	1.1	-0.2	1.2	-0.4
Medication: Levothyroxine sodium	0.9	1.6	6.0	-0.3	1.8	0.5	1.1	2.5	1.5	1.1	1.2	1.4	1.0	0.0	-0.9	0.7	1.5	1.0	1.2	0.8	1.6	1.4
Mouth/teeth dental problems	0.9	1.4	6.1	0.8	1.0	0.7	0.6	1.4	0.2	0.2	1.8	2.5	0.2	1.8	0.0	0.9	1.4	0.2	0.5	1.0	0.7	2.5
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	5.2	-0.1	0.2	-0.5	0.5	1.7	0.5	0.9	1.1	1.3	1.0	2.3	-0.8	1.6	1.3	1.0	1.4	0.3	0.1	1.0
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	5.0	-1.6	1.0	-0.1	1.7	0.7	1.2	1.4	1.0	0.4	1.5	1.5	-1.5	0.6	0.2	1.6	1.0	2.2	1.2	0.2
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	7.1	-1.1	-0.3	-0.6	-0.1	-0.5	0.9	-0.2	-1.7	-1.7	-0.3	-2.7	0.1	-2.0	-1.9	-0.3	-1.0	0.3	0.1	-1.9
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.5	0.6	0.4	0.0	0.7	-0.3	0.2	1.1	1.3	1.1	1.3	1.0	-1.2	1.6	1.4	1.5	1.2	1.1	0.7	1.4
Illnesses of father: Heart disease	0.9	1.3	4.8	-1.5	0.2	-2.2	1.5	0.6	0.8	1.4	0.6	-0.5	1.4	0.5	-1.5	1.2	0.4	1.5	1.2	0.9	0.9	-0.6
Friendships satisfaction	0.9	1.2	3.7	-1.7	1.0	-0.5	0.6	-0.1	1.0	0.7	-0.9	-1.8	0.6	-1.9	-0.8	-1.3	-1.1	0.5	-0.4	1.0	1.0	-1.5
Heart disease (siblings)	0.9	1.1	3.8	1.0	-0.8	0.5	-1.0	0.5	-1.0	-1.3	-1.1	-0.5	-1.3	-1.3	1.4	-0.6	-0.1	-1.2	-0.9	-2.0	-0.8	-0.2
Frequency of depressed mood in last 2 weeks	0.8	1.1	5.4	0.8	0.6	2.3	0.1	0.6	-0.1	0.1	1.5	1.8	0.1	1.6	-0.1	1.1	1.3	-0.1	0.5	0.1	0.5	1.9
Serious illness, injury or assault to yourself	0.8	1.0	2.9	-1.7	0.9	-1.4	1.3	0.1	1.1	1.2	0.4	-0.6	1.2	-0.0	-1.2	0.8	0.3	1.2	1.0	0.6	1.2	-0.7
Chronic bronchitis/emphysema (father)	0.8	1.0	3.3	0.7	-0.5	0.0	-1.3	0.3	-0.9	-1.4	-0.8	0.2	-1.4	-0.4	1.6	-0.8	-0.1	-1.5	-0.9	-1.8	-1.0	0.2
Pain all over the body in last month	0.8	0.9	3.2	0.5	0.7	1.2	0.6	1.2	-0.2	0.4	1.3	1.2	0.4	0.6	-0.2	1.8	1.6	0.3	1.0	-0.7	0.5	1.3
Length of working week for main job	0.8	0.9	3.1	-0.9	-0.6	-1.0	-0.6	-0.9	-0.1	-0.3	-1.3	-1.7	-0.3	-1.0	0.1	-1.1	-1.4	-0.4	-0.7	-0.5	-0.5	-1.8
Tense / ‘highly strung’	0.8	1.4	5.4	2.3	-1.1	0.6	-0.7	-1.5	-1.5	-0.9	0.9	1.1	-0.8	1.6	1.0	1.3	1.0	-0.9	0.1	-1.1	-0.7	1.5
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.5	-0.4	-0.7	1.0	-0.9	-0.9	-0.4	-1.2	-0.9	-0.6	-1.3	-0.7	1.1	-1.6	-1.5	-1.1	-1.6	0.2	-0.4	-0.6
Glaucoma (self-reported)	0.8	0.9	2.5	-0.4	1.4	0.6	1.6	0.4	0.5	1.3	0.8	0.2	1.3	0.3	-1.4	1.0	0.5	1.2	0.6	1.3	0.9	0.2
Mean time to correctly identify matches	0.8	1.5	4.5	1.1	-0.4	2.1	-1.3	-1.5	-1.1	-1.3	-1.6	-0.7	-1.2	-1.6	1.3	-1.4	-0.7	-1.0	-0.8	-1.3	-1.1	-0.6
Comparative height size at age 10	0.8	4.5	23.0	4.8	-2.0	0.8	-2.2	-1.4	-2.3	-2.0	1.0	2.6	-2.0	1.3	2.4	0.9	1.3	-2.0	-0.6	-2.0	-2.0	2.8
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	4.5	1.2	-0.8	2.1	-0.7	-1.0	-0.3	-1.0	-0.9	0.0	-1.0	-0.8	1.0	-1.4	-1.0	-0.8	-1.0	0.4	-0.6	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	3.4	0.3	0.6	1.2	0.6	0.4	0.3	0.1	1.3	1.7	0.1	1.8	0.2	1.1	1.4	0.4	0.7	0.1	0.6	1.7
Commuting to job workplace: Walk	0.8	0.8	2.7	1.0	-0.6	0.5	-1.3	0.2	-0.4	-1.3	0.1	0.8	-1.4	-0.3	1.6	-0.4	0.1	-1.4	-0.7	-1.3	-0.7	0.8
Number of self-reported non-cancer illnesses	0.8	1.4	4.0	0.8	0.7	1.2	1.1	0.8	-0.6	0.6	1.7	1.4	0.8	2.0	-0.7	2.0	1.9	0.8	1.3	0.2	0.4	1.6
Eye problems/disorders: Glaucoma	0.8	1.0	3.1	0.3	1.0	0.3	1.5	0.2	0.1	1.3	1.2	0.4	1.3	0.9	-1.4	1.8	0.9	1.0	0.8	0.9	0.6	0.4
Leg fat mass (left)	0.8	3.1	5.5	2.2	-2.1	1.8	-2.2	-1.7	-2.3	-2.3	-0.6	0.6	-2.2	0.9	2.3	-1.2	-0.7	-2.0	-2.0	-0.8	-1.9	1.0
Irritable Bowel Disease (IBD)	0.7	1.8	6.9	-2.6	1.8	-0.2	1.3	1.7	1.8	1.4	-0.2	-0.8	1.4	-1.6	-1.4	0.1	0.4	1.4	1.2	0.1	1.5	-1.0
Coronary Artery Disease (CAD)	0.7	0.8	3.2	-1.3	1.0	-0.0	1.2	0.6	1.0	0.8	0.8	0.6	0.8	-0.2	-0.9	0.0	0.4	0.9	0.6	1.8	1.5	0.7
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.5	0.6	0.9	1.0	0.3	1.6	-0.2	0.4	0.9	1.2	0.3	1.6	-0.3	0.8	1.2	0.3	0.7	-0.1	0.5	1.4
Cardiovascular Disease	0.7	2.5	10.2	2.8	-1.7	0.6	-1.1	-0.0	-3.2	-1.0	0.8	0.4	-0.9	2.9	1.0	1.5	1.2	-1.0	-0.4	-1.8	-1.6	1.3
Average weekly spirits intake	0.7	0.9	4.5	-1.1	0.1	-2.1	0.9	0.4	1.0	1.1	0.2	-0.2	1.2	0.4	-1.2	0.7	0.5	1.3	1.2	0.5	0.6	-0.4
Townsend deprivation index at recruitment	0.7	1.0	2.3	0.7	-0.9	0.9	-1.3	-0.3	-0.3	-1.1	-1.5	-0.3	-1.1	-1.1	1.4	-1.2	-0.8	-1.0	-0.6	-1.5	-1.2	-0.9
Number of incorrect matches in round	0.7	1.1	3.4	1.1	-0.5	-0.5	-1.1	-0.6	-0.5	-1.2	-1.1	-0.4	-1.3	-1.7	1.4	-0.9	-0.6	-1.4	-0.7	-1.8	-1.1	-0.7
Past tobacco smoking	0.7	1.3	4.8	-1.3	1.7	0.3	1.5	-0.2	1.8	1.0	0.7	0.9	1.0	-0.4	-0.9	-0.5	0.2	1.1	0.7	2.2	1.6	0.7
Heart attack	0.7	0.8	2.7	-1.6	0.4	-0.4	0.5	-1.2	0.8	0.6	-0.7	-1.5	0.6	-1.2	-0.8	-0.7	-1.1	0.5	-0.0	0.6	0.5	-1.6
Arm fat percentage (right)	0.7	2.7	5.7	1.9	-1.5	2.3	-2.2	-0.4	-2.1	-2.3	-0.9	0.2	-2.2	0.2	2.4	-1.2	-0.5	-2.0	-1.7	-1.5	-1.7	0.7
Alcohol intake versus 10 years previously	0.7	1.0	2.8	1.3	-1.1	1.7	-1.1	-0.3	-1.3	-1.2	-0.3	0.3	-1.2	0.9	1.1	-0.9	-0.3	-1.3	-1.0	-0.8	-1.2	0.4
Pulse rate	0.7	1.1	4.2	-0.0	0.3	-0.2	0.7	0.9	0.4	0.8	1.6	1.6	0.8	2.0	-0.8	1.3	1.4	0.7	1.0	0.9	0.6	1.6
Asthma	0.7	1.4	5.0	0.2	1.0	0.8	0.8	2.1	0.5	1.0	1.0	0.9	1.0	2.2	-0.8	1.4	1.7	1.1	1.6	-0.1	0.7	1.0
Blood clot in the leg (DVT)	0.7	0.9	3.9	-2.0	1.1	1.3	1.1	-0.5	1.6	0.7	0.2	0.4	0.6	-0.7	-0.7	-0.7	-0.3	0.7	0.5	1.6	1.0	-0.0
Medication: Paracetamol	0.7	1.2	3.1	1.1	0.8	1.4	0.6	1.3	-0.5	0.7	1.5	1.2	0.7	1.4	-0.8	1.7	1.8	0.5	0.9	-0.3	0.6	1.6
Exposure to tobacco smoke outside home	0.7	0.9	2.0	0.3	-0.9	0.4	-0.7	-0.4	-0.8	-0.9	-1.4	-1.4	-0.8	-1.4	0.8	-0.9	-0.9	-0.7	-0.8	-1.3	-0.8	-1.3
Number of children fathered	0.7	0.8	2.0	1.2	-0.3	0.2	-0.7	0.7	-0.3	-0.5	0.9	1.4	-0.5	1.0	0.7	1.2	1.4	-0.5	0.8	-1.3	-0.2	1.4
Medication: Allopurinol	0.7	0.9	3.9	1.6	-0.2	1.2	-0.8	-0.5	-0.8	-0.9	0.6	1.7	-0.9	0.5	1.1	0.2	1.0	-0.8	-0.3	-0.6	-0.3	2.0
Leg fat mass (right)	0.7	2.8	5.4	2.2	-1.9	1.7	-2.1	-1.3	-2.2	-2.3	-0.4	0.8	-2.2	0.9	2.3	-1.1	-0.5	-2.0	-1.9	-0.8	-1.8	1.2
Age at last live birth	0.7	1.0	5.6	1.5	0.0	2.4	0.2	-0.0	-0.8	-0.0	1.4	1.8	-0.1	0.8	0.0	0.7	0.7	-0.4	-0.1	0.7	-0.2	1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	3.2	-1.8	0.6	-0.3	0.5	-0.4	0.6	0.4	-0.9	-1.6	0.4	-1.7	-0.5	-0.5	-0.8	0.3	-0.1	-0.3	0.5	-1.7
Mineral and other dietary supplements	0.7	1.0	4.0	-2.0	0.8	0.3	0.9	0.4	0.9	0.9	-0.6	-1.5	0.9	-1.0	-1.1	-0.5	-0.8	0.9	0.2	0.9	0.8	-1.5
Asthma (self-reported)	0.7	1.4	4.3	0.4	0.9	0.8	0.8	2.1	0.7	0.9	1.0	1.2	1.0	2.0	-0.6	1.3	1.7	1.1	1.6	-0.0	0.6	1.2
Average weekly champagne plus white wine intake	0.7	0.9	2.8	-1.4	0.4	1.0	0.2	-1.1	0.5	0.4	-1.1	-1.3	0.4	-1.7	-0.7	-1.4	-1.1	0.5	-0.4	0.9	0.2	-1.3
Miserableness	0.7	1.2	2.6	-1.0	1.5	0.2	1.4	-1.0	1.4	1.4	0.6	-0.2	1.4	-0.5	-1.6	0.4	0.4	1.5	0.8	1.5	1.6	-0.1
Ever smoked	0.7	1.3	4.2	1.6	-1.7	-0.3	-1.4	-0.2	-1.9	-1.0	-0.4	-0.6	-1.0	0.8	0.8	0.7	0.0	-1.1	-0.7	-2.0	-1.6	-0.3
Commuting to job workplace: Cycle	0.7	0.8	3.3	0.8	-0.8	0.2	-0.9	-0.8	-0.2	-0.8	-1.1	-0.9	-0.9	-1.8	0.9	-0.8	-0.8	-0.9	-0.8	-1.1	-0.7	-0.9
Basal cell carcinoma (self-reported)	0.7	0.8	1.9	-0.3	-0.4	1.1	-1.0	1.0	0.2	-0.6	-1.2	-0.6	-0.7	-1.0	0.8	-1.4	-1.2	-0.8	-0.6	-0.9	-0.9	-1.1
Heart attack/myocardial infarction (self-reported)	0.7	0.9	3.1	-1.8	0.4	-0.6	0.7	-1.1	0.8	0.8	-0.7	-1.6	0.7	-1.1	-1.0	-0.7	-1.1	0.7	0.1	0.7	0.4	-1.7
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	3.5	-1.9	1.2	1.2	1.2	-0.2	1.6	0.8	0.5	0.6	0.7	-0.5	-0.7	-0.3	0.1	0.8	0.8	1.4	1.1	0.2
Worry (Nagel 2018)	0.6	1.2	3.7	1.9	-1.0	1.0	-0.9	-0.9	-1.7	-1.3	0.0	0.3	-1.3	0.4	1.4	0.6	0.2	-1.4	-0.6	-1.8	-1.2	0.6
Alzheimer’s Disease (including proxy)	0.6	0.9	4.3	-0.1	0.2	1.6	-0.5	-0.2	0.5	-0.6	-1.0	-0.2	-0.8	-1.4	0.7	-2.1	-1.5	-0.8	-0.9	0.6	-0.3	-0.7
Chronotype (morning person)	0.6	1.5	6.7	1.1	-0.8	-1.1	-0.0	0.3	-0.4	-0.1	1.6	2.5	-0.2	2.5	0.3	0.5	1.3	-0.3	0.3	0.6	-0.3	2.6
Multivitamins +/- minerals	0.6	0.8	1.7	0.9	-1.3	0.4	-1.1	-1.2	-1.2	-0.9	-0.7	-0.6	-0.9	0.0	0.9	-0.7	-0.8	-0.8	-1.0	-0.6	-1.2	-0.6
Forced vital capacity (FVC)	0.6	2.2	5.4	0.8	0.9	-1.3	1.2	-0.4	1.2	1.5	2.3	2.2	1.4	1.1	-1.2	1.8	1.6	1.3	1.5	1.8	1.3	2.1
Hip circumference	0.6	2.4	8.4	2.8	-1.0	1.1	-1.4	-1.0	-1.3	-1.3	1.2	2.7	-1.2	1.6	1.7	0.7	1.4	-1.1	-0.2	-0.7	-1.0	2.9
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	6.1	0.6	0.8	-0.7	1.1	-0.7	1.3	1.2	2.4	2.4	1.1	1.7	-1.0	1.1	1.1	1.0	1.0	2.5	1.2	2.2
Illnesses of mother	0.6	0.8	4.7	-0.8	0.6	-0.2	0.8	-0.2	2.2	1.1	0.6	0.5	1.0	0.5	-0.8	0.1	0.2	1.0	1.1	1.2	0.9	0.0
Exposure to tobacco smoke at home	0.6	0.6	2.6	-0.9	0.5	-0.2	0.8	-0.5	0.8	0.5	-0.4	-0.4	0.5	-1.3	-0.6	-1.5	-0.9	0.6	-0.3	1.6	0.5	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	3.3	0.9	-0.3	1.8	-0.8	0.4	-1.2	-1.1	0.6	1.0	-1.0	1.3	1.2	0.1	0.4	-1.0	-0.6	-0.5	-0.3	1.2
Loud music exposure frequency	0.6	0.7	2.5	-1.3	1.2	-0.9	0.6	0.4	1.6	0.6	0.4	0.1	0.5	-1.4	-0.4	-0.3	0.3	0.3	0.5	0.6	1.5	0.2
Pulse rate, automated reading	0.6	2.0	6.2	0.5	0.7	0.4	1.1	1.0	0.5	1.1	2.5	2.3	1.0	1.9	-1.1	1.5	1.6	0.7	1.1	1.5	1.2	2.5
Osteoporosis (self-reported)	0.6	0.8	3.0	-0.3	1.1	-0.9	1.6	-0.4	0.3	0.8	1.1	0.4	0.9	0.2	-1.1	0.3	0.4	0.9	0.5	1.7	1.2	0.6
Ever depressed for a whole week	0.6	0.7	2.0	-0.3	0.2	-0.0	-0.6	-0.3	-1.0	-0.9	-0.8	-1.4	-0.9	-1.1	0.8	-0.9	-0.9	-0.9	-1.4	-0.7	-0.1	-0.9
Cholesterol lowering medication	0.6	0.9	3.1	-1.2	0.7	-0.4	1.8	0.7	0.5	0.9	0.8	0.0	1.1	0.4	-1.0	1.1	0.9	1.5	0.8	1.1	1.4	0.3
Ulcerative Colitis (UC)	0.5	1.0	3.4	-1.7	0.9	-0.3	0.8	1.8	1.2	1.1	0.2	0.1	1.0	-0.1	-0.9	0.8	1.1	1.0	1.3	-0.6	0.9	-0.1
Body Mass Index (BMI) (2010)	0.5	0.7	3.2	-0.4	0.4	0.4	1.0	1.2	0.3	0.7	1.0	0.7	0.8	1.8	-0.8	0.8	0.6	0.7	0.6	1.0	0.5	0.7
Fed-up feelings	0.5	0.9	3.3	-1.2	1.0	0.4	1.2	-0.1	0.7	1.1	0.6	-0.3	1.1	1.0	-1.4	0.1	0.0	1.1	0.3	1.8	1.2	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	2.0	0.4	0.5	1.1	0.0	1.4	0.3	0.2	0.8	1.3	0.2	1.3	-0.0	0.6	1.2	0.1	0.8	-0.3	0.3	1.2
Qualifications: CSEs or equivalent	0.5	0.7	2.1	0.9	-0.5	1.2	-0.8	1.4	-0.1	-0.7	0.1	1.2	-0.7	1.0	1.0	0.3	0.6	-0.6	0.3	-1.2	-0.7	0.8
Stomach or abdominal pain in last month	0.5	0.6	1.1	-0.8	0.4	-1.0	1.0	-0.9	0.8	1.0	0.1	-0.2	1.0	0.7	-1.1	0.1	0.2	1.0	0.6	1.0	0.7	-0.2
Happiness	0.5	0.6	2.4	-1.2	1.2	0.4	0.6	-0.6	1.1	0.4	-0.1	-0.6	0.3	-1.5	-0.4	-0.6	-0.5	0.4	-0.2	1.0	1.0	-0.5
Noisy workplace	0.5	0.6	1.9	-0.8	0.8	-0.6	0.5	1.4	1.0	0.6	0.6	1.1	0.6	0.4	-0.4	0.6	1.1	0.7	1.0	0.1	0.7	0.7
Breastfed as a baby	0.5	0.7	2.4	0.6	-0.8	0.1	-0.6	-0.5	-1.6	-1.0	-0.7	-0.5	-1.0	-0.4	0.9	-0.2	-0.7	-1.0	-0.9	-1.1	-1.2	-0.6
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.3	-1.1	0.2	-0.8	0.1	1.0	0.7	0.7	-0.7	-0.8	0.8	-1.5	-0.7	0.2	0.1	1.1	0.7	-0.2	0.4	-1.0
Number of full brothers	0.5	0.7	5.5	0.1	0.3	2.3	-0.5	0.2	0.1	-0.8	-0.4	0.6	-0.8	-1.0	1.1	-1.3	-0.1	-0.8	-0.7	-0.1	0.0	0.6
Worry too long after embarrassment	0.5	0.9	2.7	-0.4	1.6	-0.2	1.2	-0.5	1.0	1.3	0.9	-0.1	1.3	-0.7	-1.4	0.8	0.4	0.9	0.9	0.8	1.3	-0.2
Loneliness, isolation	0.5	0.8	3.0	0.2	-0.3	1.2	-0.6	-1.7	-0.4	-0.9	-0.8	-0.8	-0.9	-0.7	0.8	-1.3	-1.1	-0.8	-1.0	0.0	-0.2	-0.7
Eye problems/disorders: Cataract	0.5	0.6	2.5	0.1	-0.4	-0.0	-0.4	-1.6	-0.0	-0.5	-0.9	-0.3	-0.5	-1.0	0.5	-1.5	-1.1	-0.4	-1.0	0.7	-0.5	-0.5
Financial situation satisfaction	0.5	0.7	2.5	-1.2	1.0	0.3	1.0	0.7	0.0	1.0	-0.2	-1.6	0.9	-0.5	-1.2	-0.1	-0.5	0.6	-0.0	0.2	0.5	-1.3
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.3	1.5	-1.1	0.7	-0.7	0.2	-1.4	-0.7	-0.1	-0.3	-0.7	0.2	0.6	0.6	0.2	-0.8	-0.3	-1.3	-0.9	0.0
Depression (Nagel 2018)	0.4	0.6	2.1	0.4	0.7	1.4	0.2	1.3	0.1	0.1	1.0	1.4	0.1	1.0	0.1	0.7	1.1	0.1	0.6	0.0	0.4	1.4
Alzheimer’s Disease (in father)	0.4	0.4	1.6	-0.6	0.2	0.3	-0.1	-0.4	0.6	-0.1	-1.0	-0.7	-0.1	-1.3	0.0	-1.1	-1.1	-0.0	-0.4	0.4	-0.2	-1.2
Lung FEV1/FVC ratio	0.4	2.0	6.8	-0.2	-0.4	2.0	-0.6	-2.6	-0.0	-1.1	-1.3	-1.2	-1.2	-1.1	0.8	-2.3	-2.4	-1.1	-2.1	1.1	-0.5	-1.3
Diabetes (mother)	0.4	0.5	1.9	0.3	0.7	-0.6	0.5	0.0	-0.3	0.3	0.9	0.9	0.4	0.5	-0.5	0.8	1.1	0.4	0.5	0.3	0.8	1.4
Taking other prescription medications	0.4	0.6	2.6	-0.0	1.6	0.8	1.1	0.3	0.1	0.7	1.0	0.4	0.8	0.1	-0.8	1.0	1.1	0.8	0.7	0.3	0.9	0.6
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.7	-0.4	1.1	1.3	0.2	0.8	1.3	-0.0	0.1	1.1	-0.0	-0.5	0.4	-0.1	0.6	0.3	0.5	0.3	0.6	0.6
Fluid intelligence score	0.4	0.9	3.3	-1.3	1.0	1.4	1.3	0.9	0.9	0.9	0.3	0.0	0.9	-0.1	-1.0	-0.5	-0.4	0.9	0.3	1.8	0.9	-0.2
Weight	0.4	1.9	4.4	2.1	-1.8	0.7	-1.7	-1.8	-1.8	-1.7	0.0	1.1	-1.6	1.0	1.7	-0.5	-0.2	-1.3	-1.3	-0.3	-1.5	1.3
Depression (self-reported)	0.4	0.5	2.2	1.2	-0.2	1.5	-0.0	-0.4	-0.6	-0.5	0.8	0.9	-0.5	0.6	0.5	0.5	0.4	-0.6	-0.2	-0.1	-0.1	1.0
Arm fat mass (right)	0.4	1.8	3.6	1.5	-1.4	1.7	-1.8	-1.2	-1.7	-1.9	-0.6	0.3	-1.8	0.2	1.9	-1.2	-0.7	-1.5	-1.7	-0.5	-1.4	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	3.9	0.6	0.0	2.0	-0.7	0.2	-0.7	-0.8	-0.2	-0.4	-0.9	-0.5	0.9	-0.2	-0.4	-1.0	-0.7	-1.0	-0.4	-0.4
Wheeze or whistling in the chest in last year	0.4	0.7	2.6	-0.9	1.4	1.6	0.9	1.3	0.9	0.9	-0.0	-0.5	0.8	-0.5	-0.8	0.3	0.3	0.7	0.8	-0.1	0.9	-0.5
Heart disease (mother)	0.4	0.5	2.1	-0.8	0.2	-1.4	0.9	0.4	-0.3	0.8	0.2	-0.9	0.9	-0.1	-1.0	0.9	0.2	0.9	0.4	0.0	0.4	-0.7
Knee pain experienced in last month	0.4	0.6	3.4	0.9	-0.2	1.3	0.5	-0.1	0.8	0.2	0.7	1.8	0.3	0.4	0.0	0.5	0.8	0.6	0.9	0.9	0.0	1.3
Illnesses of siblings: Diabetes	0.4	0.5	1.1	-0.3	0.2	-0.2	1.1	0.8	0.5	0.6	0.8	0.8	0.7	0.4	-0.6	0.9	0.8	0.9	0.9	0.8	0.8	0.8
Arm fat percentage (left)	0.4	1.7	4.1	1.3	-1.0	2.0	-1.7	-0.2	-1.8	-1.9	-0.7	0.1	-1.8	0.3	1.9	-1.1	-0.5	-1.6	-1.6	-0.9	-1.2	0.6
Mood swings	0.4	0.7	3.0	0.9	-0.5	1.6	-0.2	-1.7	-1.2	-0.4	-0.6	-1.3	-0.4	-0.6	0.1	-0.4	-0.9	-0.7	-0.8	-0.4	-0.6	-0.9
Medication: Gliclazide	0.4	0.4	1.4	-1.1	0.7	-1.2	0.7	0.2	0.8	0.5	0.4	0.2	0.5	-0.1	-0.5	0.4	0.7	0.8	0.6	0.5	1.0	0.3
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.9	0.7	0.3	0.3	-0.0	0.8	-0.2	-0.3	0.9	1.4	-0.3	0.5	0.5	0.8	1.1	-0.3	0.3	-0.4	0.3	1.4
Risk taking	0.4	0.6	2.7	0.6	-0.9	0.9	-0.5	-0.8	-1.7	-0.7	-0.6	-1.0	-0.6	0.3	0.4	0.1	-0.3	-0.5	-0.5	-1.0	-0.9	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	1.4	-1.2	1.1	0.6	0.8	0.2	1.2	0.5	-0.1	-0.3	0.5	-0.5	-0.4	-0.3	-0.3	0.6	0.4	0.8	0.8	-0.7
Depressed Affect (Nagel 2018)	0.3	0.6	1.3	-0.8	1.0	0.3	0.9	-1.1	0.6	0.7	-0.3	-1.1	0.7	-1.1	-0.9	-0.3	-0.4	0.8	0.1	0.9	0.9	-1.0
Alzheimer’s Disease (in mother)	0.3	0.4	2.5	-0.2	0.3	0.7	-0.3	-0.1	0.4	-0.4	-0.5	-0.0	-0.5	-0.8	0.5	-1.6	-1.1	-0.6	-0.7	0.8	0.0	-0.4
Ovarian Cancer	0.3	0.4	1.3	0.7	-0.8	0.4	-0.9	-0.6	-0.3	-0.8	-0.1	0.4	-0.8	0.3	1.0	-0.1	0.0	-0.8	-0.1	-1.1	-0.8	0.1
Rheumatoid Arthritis	0.3	0.4	4.1	0.4	0.2	-1.3	-0.3	0.2	0.6	-0.1	-0.5	0.1	-0.1	-2.0	0.2	-0.6	-0.4	-0.1	-0.0	-0.0	-0.0	-0.2
Respiratory disease	0.3	0.6	4.0	0.7	0.1	0.9	-0.3	2.0	0.5	-0.1	0.3	1.1	-0.1	1.0	0.6	-0.0	1.0	0.1	1.1	-0.9	-0.2	0.9
Hair Pigment	0.3	9.1	14.7	2.6	-3.4	-0.1	-3.5	-3.8	-3.7	-3.7	-2.9	-1.9	-3.6	-0.7	3.6	-3.0	-2.7	-3.5	-3.6	-2.4	-3.5	-1.2
Tanning	0.3	3.8	6.6	-2.6	1.6	-1.7	2.5	0.9	2.3	2.1	1.6	1.3	2.2	1.7	-2.0	1.5	1.4	2.4	2.0	2.5	2.1	0.9
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.3	-0.5	0.4	-0.5	0.6	-1.1	0.2	0.7	0.6	-0.2	0.7	0.6	-0.8	0.5	0.3	0.7	0.3	0.9	0.8	0.1
Angina	0.3	0.4	1.2	-1.0	0.1	0.1	1.0	-0.0	0.5	0.8	-0.0	-0.5	0.9	0.2	-0.8	1.0	0.2	1.1	0.7	0.3	0.3	-0.7
Vitamin and mineral supplements	0.3	0.5	1.9	-0.5	1.0	0.0	0.7	1.1	1.4	0.6	0.4	0.8	0.5	-0.1	-0.3	0.2	0.6	0.6	0.8	0.5	0.8	0.6
Supplements: Zinc	0.3	0.4	1.5	0.1	0.7	0.2	0.5	0.3	0.3	0.3	0.9	0.9	0.2	0.4	-0.4	-0.1	0.5	0.1	0.0	1.1	1.0	1.2
High blood pressure (mother)	0.3	0.4	2.0	0.5	-0.6	-0.4	0.1	-0.9	-1.4	-0.4	0.3	0.4	-0.4	1.1	0.2	-0.1	-0.4	-0.6	-1.0	0.7	-0.8	0.5
Had menopause	0.3	0.4	2.5	-0.4	-0.1	-0.6	0.7	-1.6	-0.3	-0.1	-0.2	-0.6	0.0	-0.3	-0.2	-0.6	-0.8	0.4	-0.6	1.4	-0.0	-0.5
Neuroticism score	0.3	0.6	1.7	0.9	0.8	1.0	0.8	-0.8	-0.3	0.3	1.3	0.7	0.3	0.8	-0.4	1.1	0.8	-0.0	0.5	0.3	0.7	1.0
Time employed in main current job	0.3	0.3	1.9	-0.2	0.5	0.2	0.3	-1.4	0.1	0.1	0.3	-0.1	0.1	-0.9	-0.3	-0.5	-0.2	0.1	-0.3	1.0	0.8	0.3
Worrier / anxious feelings	0.3	0.6	5.4	0.6	0.4	2.3	-0.1	-0.2	-0.2	-0.2	0.8	1.1	-0.3	0.6	0.4	0.2	0.4	-0.5	0.0	0.3	0.1	1.2
Medication: Ventolin 100micrograms inhaler	0.3	0.3	2.3	-0.1	-0.3	-1.1	-0.3	0.9	-0.1	0.0	0.1	0.3	0.1	1.5	0.1	0.6	0.8	0.2	0.5	-0.7	-0.1	0.4
Age at first live birth	0.3	0.6	2.9	0.9	0.2	0.4	0.2	0.1	-0.2	0.3	1.4	1.7	0.2	0.8	-0.2	0.9	0.8	-0.2	0.2	0.6	0.1	1.6
Shortness of breath walking on level ground	0.3	0.4	1.4	-0.9	0.1	0.2	0.0	0.1	0.3	-0.2	-0.9	-1.1	-0.2	-1.2	0.2	-1.2	-0.7	0.1	-0.4	-0.0	0.2	-1.0
Angina (self-reported)	0.3	0.4	1.3	-1.0	0.1	0.0	1.0	-0.2	0.5	0.7	-0.2	-0.6	0.9	0.1	-0.8	0.9	0.0	1.1	0.7	0.3	0.2	-0.9
Migraine (self-reported)	0.3	0.3	1.1	0.8	-1.0	0.4	-0.7	0.4	-0.5	-0.3	-0.3	0.2	-0.3	0.7	0.5	0.6	0.1	-0.2	0.4	-1.0	-1.1	-0.2
Medication: Omeprazole	0.3	0.4	1.3	-0.7	1.1	0.8	0.9	-0.0	0.9	0.4	0.2	0.1	0.4	0.1	-0.4	-0.3	-0.1	0.5	0.2	1.1	0.7	-0.2
Supplements: Vitamin C	0.3	0.4	1.9	-0.6	0.2	-0.2	-0.1	0.2	-0.9	-0.0	-0.3	-1.2	-0.1	-1.4	-0.2	-0.1	-0.5	-0.2	-0.5	-0.5	0.0	-1.0
Long-standing illness, disability or infirmity	0.3	0.5	1.3	-0.6	1.1	-0.7	0.7	0.4	0.5	0.5	0.7	0.5	0.5	0.6	-0.4	0.7	1.1	0.6	0.6	-0.1	0.9	0.7
Arm fat mass (left)	0.3	1.4	2.7	1.2	-1.2	1.4	-1.5	-1.0	-1.5	-1.6	-0.5	0.3	-1.6	0.2	1.6	-1.1	-0.6	-1.3	-1.5	-0.5	-1.2	0.6
Commuting to job workplace: Public transport	0.3	0.4	1.2	-0.7	-0.2	-0.7	0.6	-0.7	0.1	0.5	-0.4	-0.9	0.6	-0.0	-0.8	-0.4	-0.6	0.6	-0.2	1.1	0.1	-0.9
Medication: Lisinopril	0.3	0.4	1.2	0.2	0.7	0.8	0.7	1.1	-0.7	0.5	0.9	0.3	0.5	1.0	-0.6	0.9	0.8	0.2	0.3	-0.1	0.2	0.6
Irritability	0.3	0.6	3.3	1.8	-0.6	1.7	-0.5	-0.6	-1.0	-0.4	0.3	0.3	-0.3	0.2	0.4	0.7	0.5	-0.4	-0.0	-0.8	-0.5	0.6
Unable to work because of sickness or disability	0.3	0.4	1.8	0.7	0.7	1.3	-0.0	-0.2	-0.2	-0.2	0.6	0.8	-0.2	0.1	0.3	0.4	0.9	-0.3	0.0	-0.3	0.5	1.2
Pain experienced in last month	0.3	0.4	1.3	-0.8	-0.0	-0.4	-0.5	-0.3	-1.0	-0.5	-0.6	-1.1	-0.6	-0.2	0.3	-0.8	-0.9	-0.9	-1.1	-0.5	-0.2	-0.6
Pack years of smoking	0.3	0.5	3.8	0.6	-0.6	0.8	0.1	-1.9	-0.8	-0.1	-0.2	-0.8	-0.1	-0.9	-0.1	-0.4	-0.6	-0.1	-0.6	0.3	-0.4	-0.5
Mean Putamen Volume	0.2	0.2	0.8	0.7	-0.4	0.6	-0.4	-0.0	-0.1	-0.3	-0.0	0.1	-0.3	0.7	0.4	0.1	0.1	-0.5	0.3	-0.9	-0.6	-0.2
Neuroticism (2016)	0.2	0.3	1.1	1.1	0.5	0.8	0.3	0.3	-0.1	0.0	0.8	0.9	-0.0	0.6	0.0	0.9	0.8	-0.2	0.5	-0.3	0.2	0.9
Smoking Status	0.2	0.5	1.3	-0.4	0.5	0.2	0.6	1.1	0.4	1.0	0.5	-0.2	1.0	0.4	-1.1	1.0	0.6	0.6	1.0	-0.3	0.6	-0.3
Neuroticism	0.2	0.6	1.7	0.0	1.3	0.2	1.2	-0.2	0.5	0.8	1.0	0.6	0.7	-0.0	-0.8	0.7	0.6	0.5	0.5	0.8	1.2	0.7
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.8	0.2	0.5	0.1	-0.3	0.3	0.1	-0.6	-0.1	0.5	-0.7	-0.5	0.7	-0.9	-0.0	-0.8	-0.6	-0.4	0.1	0.5
Leg fat-free mass (left)	0.2	0.9	4.9	-0.8	0.6	-1.0	0.9	-0.8	0.8	1.0	1.0	0.8	1.0	0.6	-1.1	0.2	0.1	1.1	0.2	2.2	0.8	0.8
Leg predicted mass (left)	0.2	0.8	5.1	-0.9	0.6	-1.0	0.9	-0.9	0.7	1.0	0.9	0.8	1.0	0.5	-1.0	0.0	0.0	1.0	0.1	2.3	0.7	0.7
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.0	0.0	-0.3	0.6	-0.5	-0.3	-0.0	-0.6	-0.7	-0.5	-0.7	-0.3	0.8	-0.4	-0.5	-0.7	-0.5	-1.0	-0.5	-0.7
Hair/balding pattern: Pattern 2	0.2	0.3	1.3	0.4	-0.6	0.6	-0.4	0.3	-0.2	-0.7	-0.0	1.1	-0.6	0.5	0.9	0.1	0.5	-0.3	0.2	-0.3	-0.4	0.9
Had other major operations	0.2	0.2	3.2	0.5	0.1	1.8	0.3	-0.2	-0.3	0.0	0.4	0.1	0.0	-0.4	-0.2	0.1	0.1	-0.1	0.0	-0.0	0.2	0.3
Trunk fat-free mass	0.2	1.3	5.9	-0.5	-0.0	-1.3	0.9	-1.8	0.7	1.1	1.2	1.1	1.2	1.2	-1.2	0.7	0.3	1.3	0.4	2.4	0.6	0.9
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	3.0	1.1	-0.1	1.7	-0.5	-0.6	-0.7	-0.5	-0.1	0.0	-0.5	-0.0	0.5	-0.4	-0.1	-0.7	-0.5	-0.5	-0.4	0.3
Trunk predicted mass	0.2	1.3	5.5	-0.5	-0.0	-1.4	0.9	-1.8	0.7	1.1	1.3	1.1	1.1	1.2	-1.2	0.7	0.3	1.3	0.4	2.3	0.6	1.0
Birth weight	0.2	0.5	2.2	-0.7	0.0	-0.2	-0.0	-0.6	-0.2	0.0	-0.6	-1.5	-0.0	-1.4	-0.3	-0.5	-1.1	-0.2	-0.5	-0.1	-0.2	-1.4
Arm fat-free mass (right)	0.2	0.9	5.0	-0.4	-0.3	-1.0	0.8	-1.8	0.3	0.8	1.0	0.9	0.9	1.4	-0.9	0.3	0.1	1.0	0.0	2.2	0.2	0.8
Medication: Seretide 50 evohaler	0.2	0.2	1.3	0.1	0.3	-1.0	-0.1	-1.1	-0.3	0.2	-0.0	-0.7	0.3	-0.3	-0.4	-0.3	-0.3	0.2	-0.4	0.5	0.3	-0.2
Arm predicted mass (right)	0.2	0.8	4.2	-0.2	-0.4	-1.0	0.6	-1.9	0.1	0.6	0.8	0.8	0.6	1.4	-0.7	0.1	-0.1	0.8	-0.2	2.0	0.1	0.8
Whole body fat-free mass	0.2	0.9	5.1	-0.5	0.0	-1.2	0.7	-1.7	0.6	0.9	1.0	0.9	0.9	0.9	-1.0	0.3	0.1	1.1	0.1	2.3	0.5	0.8
Leg fat-free mass (right)	0.2	1.1	6.0	-1.0	0.6	-1.1	1.1	-1.1	0.9	1.2	0.9	0.7	1.2	0.6	-1.3	0.0	-0.0	1.2	0.3	2.4	0.8	0.6
Illnesses of father: None of the above (group 1)	0.2	0.2	0.8	-0.1	0.8	0.4	-0.3	0.5	0.3	-0.3	-0.4	-0.1	-0.4	-0.9	0.3	-0.7	-0.3	-0.5	-0.3	-0.5	0.2	-0.2
Whole body water mass	0.2	1.1	5.6	-0.6	0.1	-1.1	0.9	-1.6	0.7	1.1	1.1	0.9	1.1	1.1	-1.2	0.5	0.2	1.2	0.3	2.4	0.6	0.8
Leg predicted mass (right)	0.2	1.0	5.7	-1.0	0.6	-1.1	1.0	-1.2	0.9	1.1	0.9	0.7	1.1	0.5	-1.2	0.0	-0.1	1.2	0.2	2.4	0.7	0.5
Wears glasses or contact lenses	0.2	0.3	1.4	0.3	-0.5	-0.6	-0.4	-0.7	-1.2	-0.3	-0.4	-0.5	-0.3	-0.3	0.2	0.4	0.0	-0.3	-0.1	-1.0	-0.6	-0.2
Ever taken oral contraceptive pill	0.2	0.2	0.7	0.7	-0.4	-0.9	-0.4	0.5	-0.5	-0.3	0.1	0.0	-0.3	0.6	0.3	0.3	-0.0	-0.4	-0.2	-0.6	-0.4	-0.0
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.9	-0.4	0.6	0.7	0.9	-0.1	0.2	0.3	-0.1	-0.2	0.3	-0.4	-0.5	-0.6	-0.3	0.4	-0.2	0.9	0.4	-0.2
Number of operations (self-reported)	0.2	0.3	1.9	0.5	-0.7	0.6	-0.0	-1.4	-1.0	-0.2	0.0	-0.5	-0.2	0.2	0.0	-0.0	-0.5	-0.3	-0.8	0.1	-0.4	-0.3
Age started oral contraceptive pill	0.2	0.2	1.3	0.0	0.3	0.1	0.4	-0.8	0.1	0.1	-0.2	-0.5	0.1	-1.2	-0.2	-0.7	-0.5	0.1	-0.4	0.7	0.4	-0.3
Neuroticism (Nagel 2018)	0.1	0.1	0.5	0.3	0.6	0.6	0.4	-0.7	-0.0	0.2	0.1	-0.5	0.1	-0.7	-0.2	0.3	0.0	0.0	0.1	-0.2	0.5	-0.3
BMI	0.1	0.7	4.2	-1.8	0.6	0.0	0.5	-0.8	0.4	0.1	-0.3	-0.5	0.2	0.0	-0.4	-1.3	-1.1	0.4	-1.0	2.0	0.7	-0.2
Waist Hip Ratio (WHR)	0.1	0.7	3.4	-1.9	0.1	0.7	0.2	-0.2	0.1	-0.1	-0.8	-1.4	-0.1	-0.5	-0.2	-0.9	-1.4	-0.0	-1.0	0.4	0.1	-1.4
Sensitivity / hurt feelings	0.1	0.3	1.4	0.6	0.7	1.2	0.0	-0.8	-0.6	-0.5	0.2	-0.1	-0.5	-0.2	0.3	-0.2	-0.3	-0.7	-0.4	-0.0	0.3	0.2
Diabetes (father)	0.1	0.2	0.5	-0.1	0.2	-0.6	0.5	-0.1	0.5	0.4	0.7	0.5	0.3	0.2	-0.2	0.3	0.2	0.2	0.2	0.7	0.5	0.4
Pack years adult smoking proportion	0.1	0.2	1.7	0.5	-0.2	0.8	0.4	-1.3	-0.5	0.2	0.3	-0.3	0.2	-0.6	-0.4	0.1	-0.2	0.1	-0.2	0.4	0.1	0.0
Supplements: Glucosamine	0.1	0.2	0.4	0.4	-0.3	-0.6	0.0	-0.6	0.2	0.1	0.3	0.6	0.2	0.6	-0.2	0.6	0.4	0.5	0.5	0.4	-0.1	0.4
Body mass index (BMI)	0.1	0.3	1.9	-1.3	0.2	0.3	0.3	-0.2	0.1	0.1	-0.4	-0.4	0.1	0.2	-0.3	-1.0	-0.7	0.4	-0.6	1.4	0.3	-0.3
Waist circumference	0.1	0.3	0.7	0.0	-0.4	0.8	-0.6	-0.7	-0.6	-0.8	-0.2	0.4	-0.7	0.5	0.7	-0.7	-0.4	-0.4	-0.8	0.4	-0.4	0.4
Nervous feelings	0.1	0.3	1.1	0.6	-0.6	-0.0	-0.4	-0.4	-0.7	-0.7	-0.0	-0.2	-0.7	-0.0	0.6	0.1	-0.2	-0.9	-0.2	-1.1	-0.4	-0.1
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.5	-0.5	0.6	0.2	0.3	0.2	-0.6	-0.3	-0.0	-0.7	-0.3	-0.7	0.2	-0.1	-0.2	-0.2	-0.7	-0.0	0.6	-0.2
Medication: Simvastatin	0.1	0.2	0.6	-0.5	0.4	-0.1	0.8	0.1	-0.2	0.1	0.4	-0.0	0.3	0.8	-0.3	0.8	0.4	0.4	0.2	0.1	0.3	-0.0
Eye problems/disorders: None of the above	0.1	0.1	0.5	-0.0	-0.5	0.2	-0.4	0.7	-0.4	-0.1	0.1	-0.1	-0.1	0.5	0.1	0.4	0.3	0.0	0.2	-0.5	-0.1	0.2
Alcohol intake frequency.	0.1	0.3	2.2	0.0	-0.8	1.5	-0.1	-0.3	-0.4	-0.3	-0.8	-0.5	-0.2	-0.1	0.2	-0.7	-0.6	-0.1	-0.3	-0.0	-0.8	-0.8
Suffer from ‘nerves’	0.1	0.2	0.9	0.4	0.2	0.7	0.4	-0.9	-0.3	-0.1	0.8	0.7	-0.1	0.3	0.1	0.5	0.2	-0.0	0.2	0.5	0.2	0.7
Overall health rating	0.1	0.2	1.7	-0.1	-0.1	1.3	0.2	0.8	0.2	0.0	0.3	0.5	0.1	1.0	0.1	0.2	0.3	0.2	0.4	0.1	-0.1	0.2
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.6	0.5	-0.4	0.1	-0.1	-0.1	-0.7	0.1	0.3	-0.2	0.1	0.7	-0.2	0.8	0.2	-0.2	0.1	-0.6	-0.3	0.1
Average weekly red wine intake	0.1	0.2	0.6	-0.2	0.4	-0.5	-0.4	0.5	0.7	0.0	-0.3	-0.3	-0.0	-0.8	0.3	-0.1	0.2	-0.0	0.2	-0.7	0.5	-0.2
Breast cancer (self-reported)	0.1	0.2	0.6	0.2	0.5	0.8	0.2	-0.3	0.8	0.5	0.0	0.3	0.5	-0.2	-0.3	-0.2	0.1	0.5	0.4	0.5	0.2	-0.1
Basal metabolic rate	0.1	0.5	3.1	0.3	-0.5	-0.5	0.0	-1.7	-0.1	0.2	0.8	1.0	0.2	1.0	-0.2	0.1	-0.0	0.4	-0.3	1.6	-0.1	1.0
Arm fat-free mass (left)	0.1	0.6	5.4	0.5	-1.1	-0.2	-0.3	-2.3	-0.3	-0.1	0.4	0.7	-0.1	0.9	0.1	-0.2	-0.4	0.1	-0.6	1.3	-0.6	0.6
Myopia	0.1	0.1	0.4	-0.4	0.5	-0.1	0.5	0.2	-0.1	0.4	0.3	0.0	0.5	0.6	-0.4	0.4	0.3	0.4	0.3	0.5	0.2	0.2
Arm predicted mass (left)	0.1	0.6	4.0	0.6	-1.0	-0.2	-0.1	-2.0	-0.3	-0.1	0.6	1.0	0.0	1.2	0.0	0.1	-0.0	0.2	-0.4	1.3	-0.5	1.0
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Back pain experienced in last month	0.0	0.0	0.2	0.2	0.1	0.4	-0.0	0.1	0.2	0.2	-0.0	0.0	0.3	0.2	-0.2	0.2	0.4	0.5	0.3	0.1	0.1	0.0

Hub : Genes

DIP2B

Models

Trait associations