Hub : Genes

DIP2B

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1070	0.0330	1.3e-12	0.099	0.106	0.128	0.105	0.117	5.1e-12	7.9e-13	2.6e-15	9.9e-13	4.8e-14
2	GTEx	Adrenal Gland	0.1612	0.0730	9.8e-04	0.055	NA	0.053	NA	0.067	5.0e-03	NA	5.5e-03	NA	2.1e-03
3	GTEx	Brain Nucleus accumbens basal ganglia	0.3010	0.1390	8.0e-03	0.043	NA	0.064	NA	0.113	2.7e-02	NA	8.5e-03	NA	6.3e-04
4	GTEx	Cells Transformed fibroblasts	0.1650	0.0740	5.4e-05	0.081	NA	0.059	NA	0.085	1.2e-06	NA	3.3e-05	NA	6.2e-07
5	GTEx	Esophagus Mucosa	0.0790	0.0360	1.6e-03	0.030	NA	0.030	NA	0.021	4.0e-03	NA	4.0e-03	NA	1.3e-02
6	GTEx	Muscle Skeletal	0.0344	0.0168	2.2e-03	0.039	NA	0.031	NA	0.038	9.6e-05	NA	4.3e-04	NA	1.1e-04
7	GTEx	Stomach	0.0860	0.0430	6.2e-03	0.088	NA	0.009	NA	0.067	5.2e-05	NA	1.1e-01	NA	4.1e-04
8	GTEx	Testis	0.1390	0.0540	1.2e-04	0.083	NA	0.149	NA	0.150	1.6e-04	NA	3.8e-07	NA	3.7e-07
9	GTEx	Thyroid	0.0960	0.0310	1.0e-06	0.101	NA	0.105	NA	0.123	4.0e-08	NA	1.9e-08	NA	1.2e-09
10	GTEx	Whole Blood	0.1190	0.0480	2.5e-04	0.082	NA	0.071	NA	0.082	5.8e-08	NA	4.0e-07	NA	5.7e-08
11	METSIM	Adipose	0.0368	0.0191	3.8e-03	0.000	0.007	0.012	0.011	0.002	3.5e-01	2.6e-02	4.6e-03	8.0e-03	1.5e-01
12	YFS	Blood	0.3611	0.0629	0.0e+00	0.274	0.238	0.271	0.275	0.275	7.7e-90	9.4e-77	7.8e-89	2.8e-90	3.4e-90
13	TCGA	Bladder Urothelial Carcinoma	0.2160	0.0930	2.7e-06	0.055	0.049	0.062	NA	0.057	2.0e-05	5.3e-05	6.2e-06	NA	1.3e-05
14	TCGA	Breast Invasive Carcinoma	0.0169	0.0106	1.7e-03	0.016	0.011	0.003	NA	0.006	2.7e-04	1.7e-03	8.1e-02	NA	2.0e-02
15	TCGA	Colon Adenocarcinoma	0.1300	0.0600	8.8e-05	0.136	0.078	0.117	NA	0.123	3.0e-08	2.9e-05	2.8e-07	NA	1.3e-07
16	TCGA	Head and Neck Squamous Cell Carcinoma	0.0576	0.0391	6.4e-04	0.013	0.024	0.008	NA	0.010	1.1e-02	9.4e-04	3.8e-02	NA	2.1e-02
17	TCGA	Lung Adenocarcinoma	0.0862	0.0375	6.0e-05	0.019	0.050	0.051	NA	0.042	2.1e-03	1.5e-06	1.3e-06	NA	1.0e-05
18	TCGA	Testicular Germ Cell Tumors	0.1130	0.0640	8.6e-03	0.020	0.025	0.003	NA	0.019	6.6e-02	4.6e-02	2.5e-01	NA	6.8e-02
19	TCGA	Thyroid Carcinoma	0.1230	0.0420	1.1e-16	0.185	0.172	0.184	NA	0.185	1.1e-17	1.9e-16	1.3e-17	NA	9.2e-18

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Bipolar Disorder (2018)	1.1	1.8	5.3	1.1	-1.5	-0.7	-1.4	2.1	-1.1	-1.2	-0.0	1.2	-1.2	2.3	1.5	0.6	1.1	-1.2	-0.1	-2.1	-1.3	1.2
Bipolar Disorder or Schizophrenia	2.4	5.9	16.7	3.4	-2.4	0.8	-3.1	1.4	-2.7	-3.0	-0.4	1.4	-3.0	1.9	3.5	0.2	0.7	-3.1	-1.3	-4.1	-2.6	1.5
Depressed Affect (Nagel 2018)	0.3	0.6	1.3	-0.8	1.0	0.3	0.9	-1.1	0.6	0.7	-0.3	-1.1	0.7	-1.1	-0.9	-0.3	-0.4	0.8	0.1	0.9	0.9	-1.0
Depression (Nagel 2018)	0.4	0.6	2.1	0.4	0.7	1.4	0.2	1.3	0.1	0.1	1.0	1.4	0.1	1.0	0.1	0.7	1.1	0.1	0.6	0.0	0.4	1.4
Intelligence (Savage-Jansen 2018)	1.7	5.1	9.0	-1.6	2.4	1.0	3.0	2.2	1.8	2.7	2.4	1.1	2.8	1.7	-2.8	2.2	1.9	2.9	2.3	2.9	2.6	1.2
Neuroticism (Nagel 2018)	0.1	0.1	0.5	0.3	0.6	0.6	0.4	-0.7	-0.0	0.2	0.1	-0.5	0.1	-0.7	-0.2	0.3	0.0	0.0	0.1	-0.2	0.5	-0.3
Schizophrenia (2018)	2.4	4.9	12.4	3.5	-1.8	1.6	-2.9	0.3	-2.7	-2.9	-0.5	0.8	-2.9	0.6	3.3	-0.2	0.1	-3.1	-1.6	-3.5	-2.3	1.0
Schizophrenia vs Biploar Disorder	3.5	4.6	13.8	3.1	-1.8	3.7	-2.3	-2.1	-2.8	-2.5	-1.0	-0.5	-2.5	-1.1	2.5	-0.9	-1.2	-2.5	-2.3	-1.5	-2.1	0.0
Worry (Nagel 2018)	0.6	1.2	3.7	1.9	-1.0	1.0	-0.9	-0.9	-1.7	-1.3	0.0	0.3	-1.3	0.4	1.4	0.6	0.2	-1.4	-0.6	-1.8	-1.2	0.6
Alzheimer’s Disease (in mother)	0.3	0.4	2.5	-0.2	0.3	0.7	-0.3	-0.1	0.4	-0.4	-0.5	-0.0	-0.5	-0.8	0.5	-1.6	-1.1	-0.6	-0.7	0.8	0.0	-0.4
Alzheimer’s Disease (in father)	0.4	0.4	1.6	-0.6	0.2	0.3	-0.1	-0.4	0.6	-0.1	-1.0	-0.7	-0.1	-1.3	0.0	-1.1	-1.1	-0.0	-0.4	0.4	-0.2	-1.2
Alzheimer’s Disease (including proxy)	0.6	0.9	4.3	-0.1	0.2	1.6	-0.5	-0.2	0.5	-0.6	-1.0	-0.2	-0.8	-1.4	0.7	-2.1	-1.5	-0.8	-0.9	0.6	-0.3	-0.7
Crohns Disease (2017)	1.1	2.5	6.8	-2.6	2.5	0.2	1.8	1.2	2.0	1.8	0.2	-0.8	1.7	-2.0	-1.9	-0.3	-0.1	1.6	1.0	1.4	2.0	-1.0
Irritable Bowel Disease (IBD)	0.7	1.8	6.9	-2.6	1.8	-0.2	1.3	1.7	1.8	1.4	-0.2	-0.8	1.4	-1.6	-1.4	0.1	0.4	1.4	1.2	0.1	1.5	-1.0
Ulcerative Colitis (UC)	0.5	1.0	3.4	-1.7	0.9	-0.3	0.8	1.8	1.2	1.1	0.2	0.1	1.0	-0.1	-0.9	0.8	1.1	1.0	1.3	-0.6	0.9	-0.1
Major Depression (MDD)	1.0	1.3	4.5	0.9	-0.9	2.1	-1.3	-1.2	-0.9	-1.0	-1.1	-1.1	-0.9	-1.4	1.0	-1.0	-1.1	-0.8	-1.2	-0.7	-1.0	-1.1
Reaction Time	0.9	1.7	5.2	1.2	-0.4	2.3	-1.5	-1.4	-1.1	-1.3	-1.4	-0.5	-1.3	-1.5	1.4	-1.5	-0.8	-1.4	-1.1	-1.5	-1.3	-0.5
Verbal and Numeric Reasoning (VNR)	1.0	2.5	6.0	-1.2	1.4	1.0	1.9	1.1	1.1	1.8	1.8	1.2	1.9	1.5	-1.8	1.4	1.3	2.0	1.5	2.4	1.8	1.3
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Ovarian Cancer	0.3	0.4	1.3	0.7	-0.8	0.4	-0.9	-0.6	-0.3	-0.8	-0.1	0.4	-0.8	0.3	1.0	-0.1	0.0	-0.8	-0.1	-1.1	-0.8	0.1
Prostate Cancer	1.2	1.7	9.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	1.1	0.7	3.0	2.2	3.0	2.7	-0.4
Age at First Birth	0.9	1.3	4.2	0.2	0.5	-1.6	0.3	1.4	0.3	0.6	1.5	1.7	0.6	1.2	-0.5	1.4	1.8	0.6	1.3	0.2	0.8	2.0
Bipolar Disorder (2011)	1.5	1.4	6.7	1.2	-0.6	0.5	-0.5	2.6	-0.4	-0.4	0.8	1.8	-0.5	2.1	0.8	1.2	1.4	-0.7	0.5	-1.4	-0.5	1.6
Body Mass Index (BMI) (2010)	0.5	0.7	3.2	-0.4	0.4	0.4	1.0	1.2	0.3	0.7	1.0	0.7	0.8	1.8	-0.8	0.8	0.6	0.7	0.6	1.0	0.5	0.7
Coronary Artery Disease (CAD)	0.7	0.8	3.2	-1.3	1.0	-0.0	1.2	0.6	1.0	0.8	0.8	0.6	0.8	-0.2	-0.9	0.0	0.4	0.9	0.6	1.8	1.5	0.7
Crohns Disease (2012)	2.9	4.6	9.3	-2.9	3.1	-1.1	2.9	2.2	2.5	2.6	1.4	0.3	2.6	-0.1	-2.7	0.8	1.0	2.7	2.0	2.4	2.9	-0.0
Mean Putamen Volume	0.2	0.2	0.8	0.7	-0.4	0.6	-0.4	-0.0	-0.1	-0.3	-0.0	0.1	-0.3	0.7	0.4	0.1	0.1	-0.5	0.3	-0.9	-0.6	-0.2
Fasting Glucose	0.9	1.0	5.2	-0.7	0.6	-2.3	1.1	1.1	1.2	1.2	0.5	0.2	1.1	1.2	-0.9	0.8	0.8	0.9	1.4	0.7	0.4	-0.1
HbA1C	1.8	2.0	5.1	-2.2	2.0	0.2	2.1	2.2	1.7	1.2	0.9	0.2	1.2	-0.3	-1.3	0.3	0.7	1.4	1.4	1.8	1.7	-0.2
HDL Cholesterol	1.0	1.6	5.8	-0.5	1.5	0.7	1.5	0.2	1.5	1.0	1.1	1.3	1.2	0.4	-1.1	0.7	1.1	1.7	1.3	2.4	1.6	1.4
LDL Cholesterol	0.9	1.4	4.1	-2.0	1.0	-2.0	1.1	-0.6	1.1	0.9	-0.7	-1.4	1.0	-1.4	-1.1	-0.5	-0.5	1.5	0.4	1.2	0.8	-1.7
Lupus	1.1	1.6	6.1	2.5	-0.9	1.4	-1.5	-0.4	-0.6	-1.4	0.2	1.7	-1.4	0.1	1.8	-0.6	0.7	-1.4	0.0	-1.3	-1.1	1.8
Neuroticism (2016)	0.2	0.3	1.1	1.1	0.5	0.8	0.3	0.3	-0.1	0.0	0.8	0.9	-0.0	0.6	0.0	0.9	0.8	-0.2	0.5	-0.3	0.2	0.9
Primary Biliary Cirrhosis	1.8	2.6	6.1	1.7	-1.4	1.8	-2.2	0.5	-1.2	-1.9	-1.4	-0.4	-2.0	-0.0	2.2	-1.8	-0.8	-2.2	-1.3	-2.5	-1.9	-0.3
Rheumatoid Arthritis	0.3	0.4	4.1	0.4	0.2	-1.3	-0.3	0.2	0.6	-0.1	-0.5	0.1	-0.1	-2.0	0.2	-0.6	-0.4	-0.1	-0.0	-0.0	-0.0	-0.2
Schizophrenia (2014)	3.0	6.7	15.5	3.7	-2.2	1.6	-3.4	0.1	-3.2	-3.5	-0.9	0.5	-3.6	0.3	3.9	-0.7	-0.3	-3.7	-2.2	-3.9	-2.6	0.8
Triglycerides	1.1	1.9	4.9	-1.4	2.2	-0.3	1.5	1.8	1.8	1.5	1.1	0.7	1.4	-0.2	-1.2	1.0	1.5	1.3	1.5	0.7	2.2	0.8
Type 2 Diabetes (T2D) (2012)	0.7	0.8	2.5	0.6	0.9	1.0	0.3	1.6	-0.2	0.4	0.9	1.2	0.3	1.6	-0.3	0.8	1.2	0.3	0.7	-0.1	0.5	1.4
Ulcerative Colitis	1.5	2.1	3.6	-1.9	1.2	-1.0	1.7	1.7	1.1	1.9	1.1	0.5	1.9	1.2	-1.9	1.6	1.5	1.8	1.9	0.6	1.4	0.3
Blood Eosinophil Count	0.9	6.7	32.1	-5.7	3.7	-0.3	2.3	1.5	3.3	2.0	-1.1	-2.5	1.9	-3.3	-2.2	-1.1	-1.7	1.9	-0.5	2.6	2.7	-3.0
Blood Platelet Count	5.0	57.7	225.0	-15.0	9.3	-5.8	8.8	4.6	10.9	9.1	1.1	-3.3	8.9	-2.9	-9.3	2.3	0.3	8.7	5.0	7.5	9.0	-4.8
Blood Red Count	1.2	11.6	19.2	3.7	-4.0	1.7	-4.1	-4.0	-4.4	-4.2	-2.9	-1.7	-4.1	-1.8	3.9	-3.7	-2.7	-3.9	-3.9	-2.5	-3.6	-0.6
Blood White Count	8.7	64.4	118.8	-10.1	10.9	-1.0	10.2	8.5	10.3	9.6	6.2	3.2	9.5	1.6	-9.5	5.4	5.1	9.5	7.3	9.1	10.5	2.2
Heel T-Score	4.6	36.4	54.0	6.6	-6.8	3.9	-7.3	-6.3	-7.2	-7.1	-5.8	-3.6	-7.0	-3.2	7.0	-5.6	-4.8	-6.9	-5.9	-6.2	-7.2	-2.7
BMI	0.1	0.7	4.2	-1.8	0.6	0.0	0.5	-0.8	0.4	0.1	-0.3	-0.5	0.2	0.0	-0.4	-1.3	-1.1	0.4	-1.0	2.0	0.7	-0.2
Height	1.5	28.7	114.1	10.7	-6.8	2.6	-6.4	-4.9	-7.4	-5.9	0.4	3.4	-5.8	2.8	6.3	-0.3	0.5	-5.9	-2.4	-5.4	-6.5	4.1
Waist Hip Ratio (WHR)	0.1	0.7	3.4	-1.9	0.1	0.7	0.2	-0.2	0.1	-0.1	-0.8	-1.4	-0.1	-0.5	-0.2	-0.9	-1.4	-0.0	-1.0	0.4	0.1	-1.4
Systolic Blood Pressure	2.3	11.6	49.4	7.0	-2.4	1.7	-1.7	-0.6	-5.6	-2.1	2.8	3.8	-1.8	5.1	2.3	2.9	3.6	-1.7	0.0	-2.5	-2.5	5.4
Smoking Status	0.2	0.5	1.3	-0.4	0.5	0.2	0.6	1.1	0.4	1.0	0.5	-0.2	1.0	0.4	-1.1	1.0	0.6	0.6	1.0	-0.3	0.6	-0.3
Allergy or Eczema	1.3	3.4	8.6	1.2	1.5	-1.4	1.1	2.1	1.2	1.2	2.7	2.8	1.2	1.2	-0.9	2.6	2.9	1.2	2.2	0.3	1.7	2.9
Cardiovascular Disease	0.7	2.5	10.2	2.8	-1.7	0.6	-1.1	-0.0	-3.2	-1.0	0.8	0.4	-0.9	2.9	1.0	1.5	1.2	-1.0	-0.4	-1.8	-1.6	1.3
Hypothyroidism (self reported)	2.5	5.8	12.7	0.2	2.8	1.0	2.2	2.7	1.5	1.9	3.3	3.2	1.9	2.3	-1.8	2.4	3.3	2.0	2.5	2.0	2.6	3.6
Respiratory disease	0.3	0.6	4.0	0.7	0.1	0.9	-0.3	2.0	0.5	-0.1	0.3	1.1	-0.1	1.0	0.6	-0.0	1.0	0.1	1.1	-0.9	-0.2	0.9
Type 2 Diabetes (T2D) (2018)	3.7	6.9	13.5	-1.1	3.2	0.1	2.6	2.9	2.3	2.2	3.6	3.7	2.2	2.1	-1.9	2.6	3.2	2.1	2.6	2.5	2.9	3.5
Lung FEV1/FVC ratio	0.4	2.0	6.8	-0.2	-0.4	2.0	-0.6	-2.6	-0.0	-1.1	-1.3	-1.2	-1.2	-1.1	0.8	-2.3	-2.4	-1.1	-2.1	1.1	-0.5	-1.3
Lung FVC	5.0	25.3	48.0	-5.4	5.3	-4.2	6.5	2.8	5.5	6.7	3.9	0.8	6.7	1.3	-6.9	4.4	3.1	6.7	4.6	6.0	6.1	0.6
Neuroticism	0.2	0.6	1.7	0.0	1.3	0.2	1.2	-0.2	0.5	0.8	1.0	0.6	0.7	-0.0	-0.8	0.7	0.6	0.5	0.5	0.8	1.2	0.7
Chronotype (morning person)	0.6	1.5	6.7	1.1	-0.8	-1.1	-0.0	0.3	-0.4	-0.1	1.6	2.5	-0.2	2.5	0.3	0.5	1.3	-0.3	0.3	0.6	-0.3	2.6
Hair Pigment	0.3	9.1	14.7	2.6	-3.4	-0.1	-3.5	-3.8	-3.7	-3.7	-2.9	-1.9	-3.6	-0.7	3.6	-3.0	-2.7	-3.5	-3.6	-2.4	-3.5	-1.2
Tanning	0.3	3.8	6.6	-2.6	1.6	-1.7	2.5	0.9	2.3	2.1	1.6	1.3	2.2	1.7	-2.0	1.5	1.4	2.4	2.0	2.5	2.1	0.9
Hand grip strength (left)	2.3	6.1	14.1	-1.2	1.5	-2.3	2.8	1.4	2.2	2.9	2.9	2.1	2.9	2.8	-3.0	2.1	1.9	3.0	2.2	3.8	2.3	2.0
Number of treatments/medications taken	1.2	2.2	7.0	1.1	1.0	0.6	0.9	2.4	-0.9	0.2	1.8	1.8	0.4	2.1	-0.1	2.4	2.6	0.6	1.2	-0.8	0.6	2.1
Average weekly spirits intake	0.7	0.9	4.5	-1.1	0.1	-2.1	0.9	0.4	1.0	1.1	0.2	-0.2	1.2	0.4	-1.2	0.7	0.5	1.3	1.2	0.5	0.6	-0.4
Sensitivity / hurt feelings	0.1	0.3	1.4	0.6	0.7	1.2	0.0	-0.8	-0.6	-0.5	0.2	-0.1	-0.5	-0.2	0.3	-0.2	-0.3	-0.7	-0.4	-0.0	0.3	0.2
Frequency of depressed mood in last 2 weeks	0.8	1.1	5.4	0.8	0.6	2.3	0.1	0.6	-0.1	0.1	1.5	1.8	0.1	1.6	-0.1	1.1	1.3	-0.1	0.5	0.1	0.5	1.9
Hearing difficulty/problems: Yes	1.7	2.6	5.5	0.9	-1.7	-0.6	-1.9	-0.8	-1.5	-1.6	-2.3	-2.2	-1.5	-1.3	1.6	-1.2	-1.4	-1.3	-1.3	-2.3	-1.7	-2.0
Relative age of first facial hair	1.1	2.4	6.5	-1.2	1.1	-1.0	1.5	2.2	1.9	2.0	0.8	0.2	2.0	0.1	-1.8	2.1	1.6	1.9	2.5	-0.3	1.2	-0.3
Other serious medical condition/disability diagnosed by doctor	0.3	0.4	1.3	-0.5	0.4	-0.5	0.6	-1.1	0.2	0.7	0.6	-0.2	0.7	0.6	-0.8	0.5	0.3	0.7	0.3	0.9	0.8	0.1
Ever used hormone-replacement therapy (HRT)	1.3	1.6	3.0	-0.1	-1.6	-0.7	-1.5	-1.2	-1.6	-1.4	-1.7	-1.5	-1.3	-0.1	1.2	-1.5	-1.4	-1.0	-1.5	-0.9	-1.3	-1.1
Ever had hysterectomy (womb removed)	2.1	2.3	5.3	2.3	-2.0	0.0	-2.1	-1.9	-1.5	-1.7	-1.4	-0.3	-1.7	-0.9	1.9	-1.1	-1.0	-1.5	-1.5	-1.3	-2.1	-0.3
Systolic blood pressure, automated reading	1.7	5.1	24.6	5.0	-1.9	0.4	-1.8	-1.5	-3.9	-2.1	0.9	1.9	-2.0	2.1	2.2	1.3	1.5	-1.8	-1.2	-1.9	-2.1	2.9
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.8	0.2	0.5	0.1	-0.3	0.3	0.1	-0.6	-0.1	0.5	-0.7	-0.5	0.7	-0.9	-0.0	-0.8	-0.6	-0.4	0.1	0.5
Angina	0.3	0.4	1.2	-1.0	0.1	0.1	1.0	-0.0	0.5	0.8	-0.0	-0.5	0.9	0.2	-0.8	1.0	0.2	1.1	0.7	0.3	0.3	-0.7
Medication for hormone replacement therapy	1.9	2.1	6.3	-0.5	-1.1	-0.4	-1.2	-1.1	-1.3	-1.1	-2.2	-2.5	-1.1	-1.0	0.9	-1.7	-2.1	-0.9	-1.7	-1.0	-1.3	-2.3
Vitamin and mineral supplements	0.3	0.5	1.9	-0.5	1.0	0.0	0.7	1.1	1.4	0.6	0.4	0.8	0.5	-0.1	-0.3	0.2	0.6	0.6	0.8	0.5	0.8	0.6
Supplements: Zinc	0.3	0.4	1.5	0.1	0.7	0.2	0.5	0.3	0.3	0.3	0.9	0.9	0.2	0.4	-0.4	-0.1	0.5	0.1	0.0	1.1	1.0	1.2
Medication: Co-codamol	3.6	4.2	7.4	-1.0	2.0	-0.9	2.1	1.9	2.1	1.9	2.7	2.7	1.8	2.5	-1.7	1.8	2.2	1.9	2.1	2.2	2.2	2.4
Medication: Metformin	3.6	5.0	10.8	-0.2	2.2	-0.4	2.0	3.0	1.7	1.7	2.9	3.3	1.8	2.1	-1.5	2.5	3.2	1.8	2.5	1.3	2.1	3.1
Diabetes (father)	0.1	0.2	0.5	-0.1	0.2	-0.6	0.5	-0.1	0.5	0.4	0.7	0.5	0.3	0.2	-0.2	0.3	0.2	0.2	0.2	0.7	0.5	0.4
Diabetes (mother)	0.4	0.5	1.9	0.3	0.7	-0.6	0.5	0.0	-0.3	0.3	0.9	0.9	0.4	0.5	-0.5	0.8	1.1	0.4	0.5	0.3	0.8	1.4
Severe depression (siblings)	1.4	1.5	5.2	-0.8	1.0	-0.9	1.3	2.3	1.1	1.2	1.3	1.4	1.1	1.2	-1.0	1.6	1.5	0.9	1.4	0.3	0.9	1.1
Pack years adult smoking proportion	0.1	0.2	1.7	0.5	-0.2	0.8	0.4	-1.3	-0.5	0.2	0.3	-0.3	0.2	-0.6	-0.4	0.1	-0.2	0.1	-0.2	0.4	0.1	0.0
Impedance of leg (right)	5.2	25.1	79.6	8.9	-5.4	3.8	-6.5	-1.5	-5.9	-6.2	-0.9	2.3	-6.2	1.4	7.0	0.1	0.6	-6.3	-2.9	-7.1	-5.6	2.9
Leg fat-free mass (left)	0.2	0.9	4.9	-0.8	0.6	-1.0	0.9	-0.8	0.8	1.0	1.0	0.8	1.0	0.6	-1.1	0.2	0.1	1.1	0.2	2.2	0.8	0.8
Trunk fat percentage	2.8	11.4	23.6	4.9	-3.5	3.3	-4.5	-1.5	-4.5	-4.5	-1.4	0.8	-4.5	0.6	4.8	-1.5	-0.7	-4.2	-3.0	-3.8	-3.8	1.4
Hand grip strength (right)	1.3	3.5	7.5	-0.2	0.9	-1.6	1.9	1.3	1.3	1.8	2.5	2.2	1.9	2.7	-1.8	2.3	1.8	2.0	1.8	2.3	1.5	2.0
Townsend deprivation index at recruitment	0.7	1.0	2.3	0.7	-0.9	0.9	-1.3	-0.3	-0.3	-1.1	-1.5	-0.3	-1.1	-1.1	1.4	-1.2	-0.8	-1.0	-0.6	-1.5	-1.2	-0.9
Current tobacco smoking	2.6	4.3	10.3	-2.4	2.5	-0.1	3.2	0.9	1.9	2.8	1.4	-0.4	2.8	0.0	-3.2	1.4	1.0	2.8	2.0	2.3	2.8	-0.3
Average weekly fortified wine intake	0.9	1.1	2.3	-1.5	1.4	-1.5	1.3	1.2	1.0	1.1	0.6	-0.4	1.1	-0.1	-1.2	0.9	0.8	1.0	1.1	-0.2	1.2	-0.4
Maternal smoking around birth	2.3	3.4	10.4	-0.6	-1.2	-1.0	-0.9	-2.3	-0.9	-1.0	-2.6	-3.0	-0.9	-2.5	0.7	-2.2	-2.9	-0.5	-2.0	-0.1	-1.4	-3.2
Fed-up feelings	0.5	0.9	3.3	-1.2	1.0	0.4	1.2	-0.1	0.7	1.1	0.6	-0.3	1.1	1.0	-1.4	0.1	0.0	1.1	0.3	1.8	1.2	-0.0
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.6	2.0	0.4	0.5	1.1	0.0	1.4	0.3	0.2	0.8	1.3	0.2	1.3	-0.0	0.6	1.2	0.1	0.8	-0.3	0.3	1.2
Relative age voice broke	3.6	5.6	10.1	-1.4	1.7	0.5	2.5	2.3	2.8	2.8	2.2	2.3	2.9	1.9	-2.6	2.1	2.2	3.2	2.9	2.9	2.2	1.7
Taking other prescription medications	0.4	0.6	2.6	-0.0	1.6	0.8	1.1	0.3	0.1	0.7	1.0	0.4	0.8	0.1	-0.8	1.0	1.1	0.8	0.7	0.3	0.9	0.6
Age when periods started (menarche)	1.1	2.7	4.3	1.2	-1.0	1.4	-1.4	-1.5	-1.4	-2.1	-1.8	-1.3	-2.0	-1.7	2.1	-1.5	-1.9	-1.8	-1.8	-1.6	-1.7	-1.6
Bilateral oophorectomy (both ovaries removed)	1.9	2.1	6.1	1.7	-2.5	0.4	-2.0	-1.0	-1.9	-1.8	-1.1	-0.3	-1.8	0.5	2.0	-0.5	-0.5	-1.6	-1.1	-1.9	-1.9	-0.1
Heel bone mineral density (BMD) T-score, automated (left)	3.9	8.9	14.1	3.6	-3.7	2.2	-3.7	-3.3	-3.6	-3.7	-2.4	-1.5	-3.6	-1.3	3.6	-1.9	-2.2	-3.5	-3.2	-2.9	-3.4	-0.8
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	4.1	-1.5	2.0	0.4	1.5	-0.0	1.5	1.3	1.2	0.5	1.3	1.1	-1.4	0.5	0.8	1.3	0.9	1.9	2.0	0.8
Qualifications: CSEs or equivalent	0.5	0.7	2.1	0.9	-0.5	1.2	-0.8	1.4	-0.1	-0.7	0.1	1.2	-0.7	1.0	1.0	0.3	0.6	-0.6	0.3	-1.2	-0.7	0.8
Serious illness, injury or assault to yourself	0.8	1.0	2.9	-1.7	0.9	-1.4	1.3	0.1	1.1	1.2	0.4	-0.6	1.2	-0.0	-1.2	0.8	0.3	1.2	1.0	0.6	1.2	-0.7
High blood pressure	1.8	4.9	18.0	3.8	-1.4	0.7	-0.8	1.0	-3.9	-1.0	2.2	1.8	-0.8	4.2	0.9	3.1	2.7	-0.7	-0.0	-1.7	-1.2	3.1
Hayfever, allergic rhinitis or eczema	1.0	2.3	5.3	1.0	1.0	-2.0	0.8	1.4	1.1	1.2	2.1	2.0	1.1	1.0	-0.8	2.3	2.2	1.0	1.8	0.1	1.3	2.2
Multivitamins +/- minerals	0.6	0.8	1.7	0.9	-1.3	0.4	-1.1	-1.2	-1.2	-0.9	-0.7	-0.6	-0.9	0.0	0.9	-0.7	-0.8	-0.8	-1.0	-0.6	-1.2	-0.6
Stomach or abdominal pain in last month	0.5	0.6	1.1	-0.8	0.4	-1.0	1.0	-0.9	0.8	1.0	0.1	-0.2	1.0	0.7	-1.1	0.1	0.2	1.0	0.6	1.0	0.7	-0.2
Supplements: Glucosamine	0.1	0.2	0.4	0.4	-0.3	-0.6	0.0	-0.6	0.2	0.1	0.3	0.6	0.2	0.6	-0.2	0.6	0.4	0.5	0.5	0.4	-0.1	0.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	1.7	-0.4	1.1	1.3	0.2	0.8	1.3	-0.0	0.1	1.1	-0.0	-0.5	0.4	-0.1	0.6	0.3	0.5	0.3	0.6	0.6
Medication: Atenolol	1.9	2.4	5.4	0.9	-2.2	0.6	-1.4	-1.0	-2.3	-1.6	-1.9	-1.7	-1.4	0.6	1.3	-1.0	-1.5	-1.1	-1.7	-1.4	-2.3	-1.6
Medication: Levothyroxine sodium	0.9	1.6	6.0	-0.3	1.8	0.5	1.1	2.5	1.5	1.1	1.2	1.4	1.0	0.0	-0.9	0.7	1.5	1.0	1.2	0.8	1.6	1.4
Sitting height	1.8	13.1	42.6	6.5	-5.1	-0.7	-4.5	-4.2	-5.3	-4.0	-0.0	1.7	-3.9	1.9	4.1	0.4	-0.0	-3.9	-2.8	-3.3	-4.4	2.5
Chronic bronchitis/emphysema (father)	0.8	1.0	3.3	0.7	-0.5	0.0	-1.3	0.3	-0.9	-1.4	-0.8	0.2	-1.4	-0.4	1.6	-0.8	-0.1	-1.5	-0.9	-1.8	-1.0	0.2
High blood pressure (mother)	0.3	0.4	2.0	0.5	-0.6	-0.4	0.1	-0.9	-1.4	-0.4	0.3	0.4	-0.4	1.1	0.2	-0.1	-0.4	-0.6	-1.0	0.7	-0.8	0.5
Body mass index (BMI)	0.1	0.3	1.9	-1.3	0.2	0.3	0.3	-0.2	0.1	0.1	-0.4	-0.4	0.1	0.2	-0.3	-1.0	-0.7	0.4	-0.6	1.4	0.3	-0.3
Impedance of leg (left)	5.6	27.1	82.0	9.1	-5.9	4.2	-6.8	-2.4	-6.3	-6.5	-1.4	1.9	-6.5	1.3	7.1	-0.4	0.0	-6.6	-3.3	-7.2	-6.1	2.4
Leg predicted mass (left)	0.2	0.8	5.1	-0.9	0.6	-1.0	0.9	-0.9	0.7	1.0	0.9	0.8	1.0	0.5	-1.0	0.0	0.0	1.0	0.1	2.3	0.7	0.7
Trunk fat mass	1.8	7.7	17.2	4.1	-3.0	2.7	-3.7	-1.7	-3.8	-3.7	-0.8	1.1	-3.6	0.9	3.8	-1.1	-0.5	-3.4	-2.5	-2.7	-3.2	1.6
Waist circumference	0.1	0.3	0.7	0.0	-0.4	0.8	-0.6	-0.7	-0.6	-0.8	-0.2	0.4	-0.7	0.5	0.7	-0.7	-0.4	-0.4	-0.8	0.4	-0.4	0.4
Number of incorrect matches in round	0.7	1.1	3.4	1.1	-0.5	-0.5	-1.1	-0.6	-0.5	-1.2	-1.1	-0.4	-1.3	-1.7	1.4	-0.9	-0.6	-1.4	-0.7	-1.8	-1.1	-0.7
Past tobacco smoking	0.7	1.3	4.8	-1.3	1.7	0.3	1.5	-0.2	1.8	1.0	0.7	0.9	1.0	-0.4	-0.9	-0.5	0.2	1.1	0.7	2.2	1.6	0.7
Alcohol usually taken with meals	4.0	6.4	16.8	-4.1	2.8	-0.7	3.3	1.5	3.0	3.3	1.2	-0.4	3.3	1.0	-3.6	0.7	0.5	3.3	2.0	3.6	3.0	-0.6
Nervous feelings	0.1	0.3	1.1	0.6	-0.6	-0.0	-0.4	-0.4	-0.7	-0.7	-0.0	-0.2	-0.7	-0.0	0.6	0.1	-0.2	-0.9	-0.2	-1.1	-0.4	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.0	0.0	-0.3	0.6	-0.5	-0.3	-0.0	-0.6	-0.7	-0.5	-0.7	-0.3	0.8	-0.4	-0.5	-0.7	-0.5	-1.0	-0.5	-0.7
Hearing difficulty/problems with background noise	1.4	2.3	4.2	-0.2	1.1	0.2	1.7	1.2	0.9	1.6	1.7	1.3	1.7	2.0	-1.6	2.0	1.8	1.9	1.9	1.3	1.3	1.3
Hair/balding pattern: Pattern 2	0.2	0.3	1.3	0.4	-0.6	0.6	-0.4	0.3	-0.2	-0.7	-0.0	1.1	-0.6	0.5	0.9	0.1	0.5	-0.3	0.2	-0.3	-0.4	0.9
Had menopause	0.3	0.4	2.5	-0.4	-0.1	-0.6	0.7	-1.6	-0.3	-0.1	-0.2	-0.6	0.0	-0.3	-0.2	-0.6	-0.8	0.4	-0.6	1.4	-0.0	-0.5
Had other major operations	0.2	0.2	3.2	0.5	0.1	1.8	0.3	-0.2	-0.3	0.0	0.4	0.1	0.0	-0.4	-0.2	0.1	0.1	-0.1	0.0	-0.0	0.2	0.3
Forced vital capacity (FVC)	0.6	2.2	5.4	0.8	0.9	-1.3	1.2	-0.4	1.2	1.5	2.3	2.2	1.4	1.1	-1.2	1.8	1.6	1.3	1.5	1.8	1.3	2.1
Heel bone mineral density (BMD) T-score, automated (right)	5.3	12.1	16.5	2.9	-3.8	2.7	-4.0	-3.4	-3.8	-4.0	-3.6	-2.9	-4.0	-2.3	3.8	-3.2	-3.6	-4.0	-4.1	-3.1	-3.8	-2.4
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.5	-0.5	0.6	0.2	0.3	0.2	-0.6	-0.3	-0.0	-0.7	-0.3	-0.7	0.2	-0.1	-0.2	-0.2	-0.7	-0.0	0.6	-0.2
Qualifications: None of the above	3.5	7.6	18.0	1.4	-2.9	0.0	-3.0	-2.1	-2.6	-2.9	-3.4	-2.9	-2.9	-2.6	2.8	-1.9	-2.3	-3.0	-2.4	-4.2	-3.3	-2.9
Financial difficulties in last 2 years	3.4	4.5	11.0	1.8	-2.3	0.4	-2.1	-2.1	-3.3	-2.5	-2.2	-2.3	-2.3	-0.5	2.1	-1.6	-2.0	-2.2	-2.9	-1.9	-2.3	-1.5
Mouth/teeth dental problems	0.9	1.4	6.1	0.8	1.0	0.7	0.6	1.4	0.2	0.2	1.8	2.5	0.2	1.8	0.0	0.9	1.4	0.2	0.5	1.0	0.7	2.5
Heart attack	0.7	0.8	2.7	-1.6	0.4	-0.4	0.5	-1.2	0.8	0.6	-0.7	-1.5	0.6	-1.2	-0.8	-0.7	-1.1	0.5	-0.0	0.6	0.5	-1.6
Allergy	1.4	3.1	6.9	-0.1	-1.6	1.1	-1.4	-1.9	-1.6	-1.7	-2.2	-2.1	-1.7	-1.3	1.3	-2.6	-2.6	-1.6	-2.4	-0.4	-1.7	-2.1
Pain all over the body in last month	0.8	0.9	3.2	0.5	0.7	1.2	0.6	1.2	-0.2	0.4	1.3	1.2	0.4	0.6	-0.2	1.8	1.6	0.3	1.0	-0.7	0.5	1.3
Diabetes (self-reported)	3.6	5.5	13.2	-0.5	2.4	-0.4	2.1	3.2	1.9	1.7	3.1	3.6	1.7	2.4	-1.3	2.6	3.3	1.7	2.5	1.4	2.2	3.3
Hayfever/allergic rhinitis (self-reported)	1.8	2.4	5.4	-0.1	1.4	-0.8	1.7	1.2	1.4	1.5	2.3	1.8	1.5	1.2	-1.3	1.9	2.0	1.4	1.5	1.3	1.9	2.1
Medication: Ramipril	4.6	5.9	10.7	-1.0	2.0	-0.2	2.3	2.9	1.3	2.5	3.0	2.6	2.6	3.2	-2.3	3.3	3.3	2.6	3.0	1.4	1.7	2.4
Medication: Simvastatin	0.1	0.2	0.6	-0.5	0.4	-0.1	0.8	0.1	-0.2	0.1	0.4	-0.0	0.3	0.8	-0.3	0.8	0.4	0.4	0.2	0.1	0.3	-0.0
Fluid intelligence score	0.4	0.9	3.3	-1.3	1.0	1.4	1.3	0.9	0.9	0.9	0.3	0.0	0.9	-0.1	-1.0	-0.5	-0.4	0.9	0.3	1.8	0.9	-0.2
Illnesses of siblings	1.3	1.9	5.0	-2.2	2.0	0.5	1.5	-0.2	1.9	1.6	0.5	-0.3	1.5	-0.6	-1.9	-0.7	-0.7	1.2	0.7	2.2	1.5	-0.8
Neuroticism score	0.3	0.6	1.7	0.9	0.8	1.0	0.8	-0.8	-0.3	0.3	1.3	0.7	0.3	0.8	-0.4	1.1	0.8	-0.0	0.5	0.3	0.7	1.0
Weight	0.4	1.9	4.4	2.1	-1.8	0.7	-1.7	-1.8	-1.8	-1.7	0.0	1.1	-1.6	1.0	1.7	-0.5	-0.2	-1.3	-1.3	-0.3	-1.5	1.3
Impedance of arm (right)	3.6	17.0	50.3	7.1	-3.8	3.3	-5.6	-0.9	-4.7	-5.3	-1.2	1.5	-5.3	-0.5	6.0	-0.5	0.1	-5.5	-2.5	-6.1	-4.4	1.9
Arm fat percentage (right)	0.7	2.7	5.7	1.9	-1.5	2.3	-2.2	-0.4	-2.1	-2.3	-0.9	0.2	-2.2	0.2	2.4	-1.2	-0.5	-2.0	-1.7	-1.5	-1.7	0.7
Trunk fat-free mass	0.2	1.3	5.9	-0.5	-0.0	-1.3	0.9	-1.8	0.7	1.1	1.2	1.1	1.2	1.2	-1.2	0.7	0.3	1.3	0.4	2.4	0.6	0.9
Hip circumference	0.6	2.4	8.4	2.8	-1.0	1.1	-1.4	-1.0	-1.3	-1.3	1.2	2.7	-1.2	1.6	1.7	0.7	1.4	-1.1	-0.2	-0.7	-1.0	2.9
Time employed in main current job	0.3	0.3	1.9	-0.2	0.5	0.2	0.3	-1.4	0.1	0.1	0.3	-0.1	0.1	-0.9	-0.3	-0.5	-0.2	0.1	-0.3	1.0	0.8	0.3
Alcohol intake versus 10 years previously	0.7	1.0	2.8	1.3	-1.1	1.7	-1.1	-0.3	-1.3	-1.2	-0.3	0.3	-1.2	0.9	1.1	-0.9	-0.3	-1.3	-1.0	-0.8	-1.2	0.4
Father’s age at death	2.8	3.7	6.0	0.9	-2.5	0.7	-2.4	-1.5	-1.9	-1.8	-2.4	-2.1	-1.9	-1.5	1.7	-1.6	-2.0	-2.0	-1.7	-2.5	-2.3	-2.1
Worrier / anxious feelings	0.3	0.6	5.4	0.6	0.4	2.3	-0.1	-0.2	-0.2	-0.2	0.8	1.1	-0.3	0.6	0.4	0.2	0.4	-0.5	0.0	0.3	0.1	1.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	3.0	1.1	-0.1	1.7	-0.5	-0.6	-0.7	-0.5	-0.1	0.0	-0.5	-0.0	0.5	-0.4	-0.1	-0.7	-0.5	-0.5	-0.4	0.3
Falls in the last year	1.8	2.4	5.1	-0.9	1.8	-0.5	1.9	2.0	1.8	1.6	0.9	1.4	1.7	-0.3	-1.5	1.0	1.7	2.3	1.9	1.7	1.9	1.1
Hair/balding pattern: Pattern 3	2.9	4.3	12.0	-3.2	1.9	-3.5	2.5	0.7	2.7	2.3	-0.4	-1.7	2.3	-1.6	-2.4	-0.0	-0.0	2.5	1.5	1.4	2.2	-2.1
Number of live births	1.3	1.9	8.5	1.0	-0.3	2.9	-1.2	-0.7	-1.2	-1.5	-1.1	-0.8	-1.5	-1.7	1.4	-1.5	-1.5	-1.5	-1.7	-0.8	-1.0	-0.8
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	6.1	0.6	0.8	-0.7	1.1	-0.7	1.3	1.2	2.4	2.4	1.1	1.7	-1.0	1.1	1.1	1.0	1.0	2.5	1.2	2.2
Pulse rate	0.7	1.1	4.2	-0.0	0.3	-0.2	0.7	0.9	0.4	0.8	1.6	1.6	0.8	2.0	-0.8	1.3	1.4	0.7	1.0	0.9	0.6	1.6
Happiness	0.5	0.6	2.4	-1.2	1.2	0.4	0.6	-0.6	1.1	0.4	-0.1	-0.6	0.3	-1.5	-0.4	-0.6	-0.5	0.4	-0.2	1.0	1.0	-0.5
Noisy workplace	0.5	0.6	1.9	-0.8	0.8	-0.6	0.5	1.4	1.0	0.6	0.6	1.1	0.6	0.4	-0.4	0.6	1.1	0.7	1.0	0.1	0.7	0.7
Qualifications: A levels/AS levels or equivalent	1.5	3.4	6.4	-2.0	1.5	0.1	2.4	1.0	2.2	2.5	1.7	0.5	2.5	1.4	-2.5	1.4	0.9	2.3	1.8	2.4	2.1	0.4
Serious illness, injury or assault of a close relative in last 2 years	1.6	1.9	4.3	-2.1	1.3	-1.5	1.7	1.6	1.4	1.6	1.2	-0.1	1.6	0.7	-1.6	1.5	1.0	1.4	1.6	0.3	1.6	-0.3
Mouth/teeth dental problems: Dentures	1.3	2.1	6.5	-0.3	-1.1	1.0	-1.2	-1.5	-0.8	-1.0	-2.0	-2.3	-1.0	-1.7	0.8	-1.4	-1.9	-1.1	-1.2	-1.5	-1.4	-2.5
Asthma	0.7	1.4	5.0	0.2	1.0	0.8	0.8	2.1	0.5	1.0	1.0	0.9	1.0	2.2	-0.8	1.4	1.7	1.1	1.6	-0.1	0.7	1.0
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.2	5.2	-0.1	0.2	-0.5	0.5	1.7	0.5	0.9	1.1	1.3	1.0	2.3	-0.8	1.6	1.3	1.0	1.4	0.3	0.1	1.0
Medication: Cholesterol lowering	1.6	2.4	5.6	-1.8	2.4	0.1	2.1	0.8	1.5	1.9	1.6	0.6	1.9	1.1	-2.0	1.1	1.0	1.9	1.5	1.9	1.8	0.4
Depression (self-reported)	0.4	0.5	2.2	1.2	-0.2	1.5	-0.0	-0.4	-0.6	-0.5	0.8	0.9	-0.5	0.6	0.5	0.5	0.4	-0.6	-0.2	-0.1	-0.1	1.0
Medication: Lansoprazole	1.9	2.2	8.1	-1.3	1.4	-0.3	1.2	2.8	2.0	1.0	1.6	1.8	1.0	1.3	-0.7	1.0	1.6	1.3	1.7	0.8	1.7	1.5
Prospective memory result	1.9	2.3	3.9	-0.7	1.6	-1.8	1.5	0.8	1.2	1.4	1.8	1.2	1.5	1.0	-1.5	2.0	2.0	1.7	1.8	0.8	2.0	1.4
Lung cancer (father)	1.0	1.2	2.9	-0.1	1.4	0.6	1.2	1.7	0.4	1.1	1.2	1.2	1.1	0.7	-1.0	1.4	1.6	0.8	1.4	-0.1	0.7	1.0
Illnesses of mother	0.6	0.8	4.7	-0.8	0.6	-0.2	0.8	-0.2	2.2	1.1	0.6	0.5	1.0	0.5	-0.8	0.1	0.2	1.0	1.1	1.2	0.9	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.9	9.3	0.3	1.8	-0.2	1.8	0.4	2.0	1.8	3.1	3.0	1.7	1.9	-1.6	1.8	2.0	1.6	1.8	2.6	2.1	2.8
Pulse wave Arterial Stiffness index	2.8	3.3	5.6	1.5	-1.5	1.2	-2.0	-1.9	-2.1	-2.4	-1.8	-1.2	-2.3	-1.3	2.3	-1.7	-1.5	-2.2	-2.1	-1.7	-1.8	-0.9
Impedance of arm (left)	2.8	13.1	40.8	6.4	-3.3	2.8	-4.9	-0.5	-4.3	-4.6	-1.0	1.4	-4.6	-0.2	5.2	-0.4	0.2	-4.8	-2.2	-5.5	-3.9	1.7
Arm fat mass (right)	0.4	1.8	3.6	1.5	-1.4	1.7	-1.8	-1.2	-1.7	-1.9	-0.6	0.3	-1.8	0.2	1.9	-1.2	-0.7	-1.5	-1.7	-0.5	-1.4	0.7
Trunk predicted mass	0.2	1.3	5.5	-0.5	-0.0	-1.4	0.9	-1.8	0.7	1.1	1.3	1.1	1.1	1.2	-1.2	0.7	0.3	1.3	0.4	2.3	0.6	1.0
Standing height	1.5	14.9	61.3	7.8	-4.6	1.3	-4.7	-3.9	-4.5	-4.2	0.5	3.3	-4.2	1.5	4.8	0.6	0.6	-4.3	-2.2	-3.6	-4.4	3.5
Length of working week for main job	0.8	0.9	3.1	-0.9	-0.6	-1.0	-0.6	-0.9	-0.1	-0.3	-1.3	-1.7	-0.3	-1.0	0.1	-1.1	-1.4	-0.4	-0.7	-0.5	-0.5	-1.8
Exposure to tobacco smoke at home	0.6	0.6	2.6	-0.9	0.5	-0.2	0.8	-0.5	0.8	0.5	-0.4	-0.4	0.5	-1.3	-0.6	-1.5	-0.9	0.6	-0.3	1.6	0.5	-0.6
Breastfed as a baby	0.5	0.7	2.4	0.6	-0.8	0.1	-0.6	-0.5	-1.6	-1.0	-0.7	-0.5	-1.0	-0.4	0.9	-0.2	-0.7	-1.0	-0.9	-1.1	-1.2	-0.6
Tense / ‘highly strung’	0.8	1.4	5.4	2.3	-1.1	0.6	-0.7	-1.5	-1.5	-0.9	0.9	1.1	-0.8	1.6	1.0	1.3	1.0	-0.9	0.1	-1.1	-0.7	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	0.9	3.3	0.9	-0.3	1.8	-0.8	0.4	-1.2	-1.1	0.6	1.0	-1.0	1.3	1.2	0.1	0.4	-1.0	-0.6	-0.5	-0.3	1.2
Hair/balding pattern: Pattern 4	8.3	20.2	38.1	-6.2	5.8	-2.3	5.5	3.1	6.0	6.1	3.3	0.6	5.8	0.2	-6.2	2.5	2.2	5.2	4.3	4.8	5.7	0.1
Birth weight of first child	1.2	2.2	5.9	-2.4	1.3	0.2	0.9	-1.3	1.6	1.2	-0.7	-1.9	1.1	-2.4	-1.5	-1.7	-1.7	0.8	-0.3	2.0	1.2	-2.0
Peak expiratory flow (PEF)	1.2	2.7	9.3	1.4	0.1	-0.6	0.6	-0.5	0.4	0.8	2.8	2.8	0.7	3.0	-0.5	2.0	1.9	0.7	1.0	1.6	0.7	3.0
Pulse wave reflection index	3.9	4.8	11.1	0.2	-1.1	0.3	-1.7	-2.6	-1.8	-2.1	-2.9	-3.3	-2.0	-2.8	1.8	-2.6	-2.7	-2.0	-2.8	-1.6	-1.4	-2.8
Ever highly irritable/argumentative for 2 days	0.8	1.0	2.5	-0.4	-0.7	1.0	-0.9	-0.9	-0.4	-1.2	-0.9	-0.6	-1.3	-0.7	1.1	-1.6	-1.5	-1.1	-1.6	0.2	-0.4	-0.6
Loud music exposure frequency	0.6	0.7	2.5	-1.3	1.2	-0.9	0.6	0.4	1.6	0.6	0.4	0.1	0.5	-1.4	-0.4	-0.3	0.3	0.3	0.5	0.6	1.5	0.2
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	5.0	-1.6	1.0	-0.1	1.7	0.7	1.2	1.4	1.0	0.4	1.5	1.5	-1.5	0.6	0.2	1.6	1.0	2.2	1.2	0.2
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.6	0.3	-0.8	0.5	-1.4	-0.5	-0.7	-1.2	-1.6	-1.4	-1.2	-1.6	1.2	-1.4	-1.2	-1.2	-1.1	-1.5	-1.0	-1.3
Blood clot in the leg (DVT)	0.7	0.9	3.9	-2.0	1.1	1.3	1.1	-0.5	1.6	0.7	0.2	0.4	0.6	-0.7	-0.7	-0.7	-0.3	0.7	0.5	1.6	1.0	-0.0
Medication: Paracetamol	0.7	1.2	3.1	1.1	0.8	1.4	0.6	1.3	-0.5	0.7	1.5	1.2	0.7	1.4	-0.8	1.7	1.8	0.5	0.9	-0.3	0.6	1.6
Headache pain in last month	1.4	2.4	4.6	-0.0	1.4	0.4	2.1	1.2	0.5	1.9	2.0	0.9	1.9	1.4	-2.1	2.0	1.6	1.8	1.6	1.4	1.5	1.2
Medication for cholesterol, blood pressure or diabetes	0.9	1.5	7.1	-1.1	-0.3	-0.6	-0.1	-0.5	0.9	-0.2	-1.7	-1.7	-0.3	-2.7	0.1	-2.0	-1.9	-0.3	-1.0	0.3	0.1	-1.9
Glaucoma (self-reported)	0.8	0.9	2.5	-0.4	1.4	0.6	1.6	0.4	0.5	1.3	0.8	0.2	1.3	0.3	-1.4	1.0	0.5	1.2	0.6	1.3	0.9	0.2
Gout (self-reported)	1.0	1.4	4.8	2.2	-0.7	1.7	-1.3	-1.4	-1.4	-1.4	-0.1	0.7	-1.4	-0.5	1.5	-0.2	0.3	-1.4	-0.9	-1.3	-0.7	1.2
Hypothyroidism/myxoedema (self-reported)	1.9	3.8	6.5	-0.4	2.5	0.9	1.9	2.3	1.7	1.7	2.4	2.2	1.7	1.1	-1.6	1.7	2.4	1.8	1.9	1.9	2.5	2.5
Medication: Amlodipine	2.2	3.1	8.7	3.0	-1.1	0.9	-1.5	1.1	-2.7	-2.1	0.3	1.4	-1.9	1.4	2.3	0.9	1.5	-1.7	-0.5	-2.9	-1.2	2.0
Medication: Ventolin 100micrograms inhaler	0.3	0.3	2.3	-0.1	-0.3	-1.1	-0.3	0.9	-0.1	0.0	0.1	0.3	0.1	1.5	0.1	0.6	0.8	0.2	0.5	-0.7	-0.1	0.4
Birth weight	0.2	0.5	2.2	-0.7	0.0	-0.2	-0.0	-0.6	-0.2	0.0	-0.6	-1.5	-0.0	-1.4	-0.3	-0.5	-1.1	-0.2	-0.5	-0.1	-0.2	-1.4
Chronic bronchitis/emphysema (mother)	0.5	0.6	2.3	-1.1	0.2	-0.8	0.1	1.0	0.7	0.7	-0.7	-0.8	0.8	-1.5	-0.7	0.2	0.1	1.1	0.7	-0.2	0.4	-1.0
High blood pressure (siblings)	1.4	2.0	6.7	2.6	-1.9	-0.7	-1.1	0.6	-2.3	-1.1	0.3	0.4	-0.9	2.1	1.1	1.8	1.4	-0.6	-0.2	-2.0	-1.2	1.2
Forced vital capacity (FVC), Best measure	1.1	3.9	10.3	1.0	1.6	-0.5	1.5	0.4	1.5	1.7	3.2	3.2	1.7	1.9	-1.4	2.4	2.5	1.5	2.1	1.8	1.8	3.1
Body fat percentage	2.1	8.4	16.6	4.0	-3.0	3.2	-3.8	-1.4	-3.9	-4.0	-1.3	0.6	-3.8	0.7	4.1	-1.5	-0.7	-3.6	-2.8	-3.0	-3.3	1.2
Leg fat percentage (right)	1.3	4.6	9.3	2.8	-2.4	2.7	-2.8	-0.9	-2.9	-3.0	-0.9	0.5	-2.8	0.9	3.0	-1.2	-0.5	-2.5	-2.1	-1.9	-2.3	1.0
Arm fat-free mass (right)	0.2	0.9	5.0	-0.4	-0.3	-1.0	0.8	-1.8	0.3	0.8	1.0	0.9	0.9	1.4	-0.9	0.3	0.1	1.0	0.0	2.2	0.2	0.8
Exposure to tobacco smoke outside home	0.7	0.9	2.0	0.3	-0.9	0.4	-0.7	-0.4	-0.8	-0.9	-1.4	-1.4	-0.8	-1.4	0.8	-0.9	-0.9	-0.7	-0.8	-1.3	-0.8	-1.3
Comparative body size at age 10	1.4	3.9	14.6	-3.8	2.3	-0.5	1.9	0.1	2.7	2.0	-0.5	-1.9	1.8	-2.1	-2.4	-1.4	-1.7	1.3	0.0	2.5	1.9	-2.3
Number of full brothers	0.5	0.7	5.5	0.1	0.3	2.3	-0.5	0.2	0.1	-0.8	-0.4	0.6	-0.8	-1.0	1.1	-1.3	-0.1	-0.8	-0.7	-0.1	0.0	0.6
Worry too long after embarrassment	0.5	0.9	2.7	-0.4	1.6	-0.2	1.2	-0.5	1.0	1.3	0.9	-0.1	1.3	-0.7	-1.4	0.8	0.4	0.9	0.9	0.8	1.3	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	3.9	0.6	0.0	2.0	-0.7	0.2	-0.7	-0.8	-0.2	-0.4	-0.9	-0.5	0.9	-0.2	-0.4	-1.0	-0.7	-1.0	-0.4	-0.4
Wheeze or whistling in the chest in last year	0.4	0.7	2.6	-0.9	1.4	1.6	0.9	1.3	0.9	0.9	-0.0	-0.5	0.8	-0.5	-0.8	0.3	0.3	0.7	0.8	-0.1	0.9	-0.5
Number of children fathered	0.7	0.8	2.0	1.2	-0.3	0.2	-0.7	0.7	-0.3	-0.5	0.9	1.4	-0.5	1.0	0.7	1.2	1.4	-0.5	0.8	-1.3	-0.2	1.4
Reason for reducing amount of alcohol drunk: Health precaution	2.7	3.1	8.9	3.0	-2.0	0.2	-2.4	-0.9	-2.6	-2.0	-0.7	0.0	-2.1	-0.3	2.2	-0.1	-0.1	-2.3	-1.3	-2.8	-2.0	0.5
Age at first live birth	0.3	0.6	2.9	0.9	0.2	0.4	0.2	0.1	-0.2	0.3	1.4	1.7	0.2	0.8	-0.2	0.9	0.8	-0.2	0.2	0.6	0.1	1.6
Pulse wave peak to peak time	1.9	2.2	3.5	-0.9	1.0	-1.0	1.5	1.4	1.7	1.9	1.6	1.4	1.9	1.2	-1.8	1.6	1.5	1.8	1.9	1.3	1.3	1.1
Health satisfaction	1.4	1.8	9.1	-1.5	0.8	0.8	0.4	-0.5	0.2	-0.1	-1.4	-2.4	-0.3	-3.0	0.1	-1.7	-1.8	-0.5	-1.2	-0.0	0.5	-2.3
Shortness of breath walking on level ground	0.3	0.4	1.4	-0.9	0.1	0.2	0.0	0.1	0.3	-0.2	-0.9	-1.1	-0.2	-1.2	0.2	-1.2	-0.7	0.1	-0.4	-0.0	0.2	-1.0
Qualifications: College or University degree	1.6	5.1	10.4	-2.0	2.3	-1.9	2.5	2.1	3.2	2.8	2.2	1.5	2.6	1.3	-2.5	2.0	1.9	2.4	2.3	2.3	2.8	1.3
Eye problems/disorders: None of the above	0.1	0.1	0.5	-0.0	-0.5	0.2	-0.4	0.7	-0.4	-0.1	0.1	-0.1	-0.1	0.5	0.1	0.4	0.3	0.0	0.2	-0.5	-0.1	0.2
Mouth/teeth dental problems: Loose teeth	1.4	1.7	4.6	-1.1	1.5	0.5	1.4	2.1	1.1	1.5	1.1	0.6	1.6	0.9	-1.6	0.5	1.2	1.6	1.3	1.2	1.6	0.8
Emphysema/chronic bronchitis	1.1	1.2	2.7	-1.5	0.9	-0.6	1.2	-0.6	1.5	1.5	0.7	0.0	1.5	0.2	-1.5	0.9	0.2	1.5	1.2	1.6	1.0	-0.3
Medication for pain relief, constipation, heartburn	1.3	2.1	4.2	0.9	-1.9	-0.4	-1.8	-1.9	-0.8	-1.6	-1.5	-0.9	-1.7	-1.1	1.6	-2.1	-1.8	-1.8	-1.7	-0.6	-1.4	-0.8
Neck or shoulder pain in last month	1.1	1.6	4.4	-0.2	0.6	-0.4	1.0	1.6	1.3	1.1	1.5	1.7	1.1	2.1	-0.8	1.5	1.7	1.2	1.6	0.7	0.8	1.3
Medication: Blood pressure	1.3	2.3	8.1	2.3	-0.7	0.7	-0.5	1.4	-2.0	-0.5	1.5	2.0	-0.4	2.8	0.6	2.2	1.9	-0.3	0.5	-1.0	-0.9	2.3
Angina (self-reported)	0.3	0.4	1.3	-1.0	0.1	0.0	1.0	-0.2	0.5	0.7	-0.2	-0.6	0.9	0.1	-0.8	0.9	0.0	1.1	0.7	0.3	0.2	-0.9
Migraine (self-reported)	0.3	0.3	1.1	0.8	-1.0	0.4	-0.7	0.4	-0.5	-0.3	-0.3	0.2	-0.3	0.7	0.5	0.6	0.1	-0.2	0.4	-1.0	-1.1	-0.2
Medication: Ibuprofen	1.3	1.6	6.7	-0.1	0.3	-0.8	0.6	2.6	0.7	1.0	1.2	1.5	1.0	2.0	-0.8	1.9	1.7	1.0	1.7	-0.2	0.2	1.0
Medication: Allopurinol	0.7	0.9	3.9	1.6	-0.2	1.2	-0.8	-0.5	-0.8	-0.9	0.6	1.7	-0.9	0.5	1.1	0.2	1.0	-0.8	-0.3	-0.6	-0.3	2.0
Medication: Omeprazole	0.3	0.4	1.3	-0.7	1.1	0.8	0.9	-0.0	0.9	0.4	0.2	0.1	0.4	0.1	-0.4	-0.3	-0.1	0.5	0.2	1.1	0.7	-0.2
Medication: Seretide 50 evohaler	0.2	0.2	1.3	0.1	0.3	-1.0	-0.1	-1.1	-0.3	0.2	-0.0	-0.7	0.3	-0.3	-0.4	-0.3	-0.3	0.2	-0.4	0.5	0.3	-0.2
Mean time to correctly identify matches	0.8	1.5	4.5	1.1	-0.4	2.1	-1.3	-1.5	-1.1	-1.3	-1.6	-0.7	-1.2	-1.6	1.3	-1.4	-0.7	-1.0	-0.8	-1.3	-1.1	-0.6
Heart disease (mother)	0.4	0.5	2.1	-0.8	0.2	-1.4	0.9	0.4	-0.3	0.8	0.2	-0.9	0.9	-0.1	-1.0	0.9	0.2	0.9	0.4	0.0	0.4	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.4	2.9	6.3	0.1	-1.1	0.6	-1.9	-0.9	-1.3	-1.5	-2.4	-2.5	-1.5	-1.9	1.3	-2.5	-2.3	-1.5	-2.1	-1.1	-1.3	-2.2
Whole body fat mass	1.2	4.9	9.6	3.1	-2.4	2.3	-2.9	-1.5	-3.0	-3.0	-0.7	0.9	-2.9	0.9	3.1	-1.2	-0.5	-2.7	-2.2	-1.7	-2.5	1.4
Leg fat mass (right)	0.7	2.8	5.4	2.2	-1.9	1.7	-2.1	-1.3	-2.2	-2.3	-0.4	0.8	-2.2	0.9	2.3	-1.1	-0.5	-2.0	-1.9	-0.8	-1.8	1.2
Arm predicted mass (right)	0.2	0.8	4.2	-0.2	-0.4	-1.0	0.6	-1.9	0.1	0.6	0.8	0.8	0.6	1.4	-0.7	0.1	-0.1	0.8	-0.2	2.0	0.1	0.8
Pulse rate, automated reading	0.6	2.0	6.2	0.5	0.7	0.4	1.1	1.0	0.5	1.1	2.5	2.3	1.0	1.9	-1.1	1.5	1.6	0.7	1.1	1.5	1.2	2.5
Alcohol intake frequency.	0.1	0.3	2.2	0.0	-0.8	1.5	-0.1	-0.3	-0.4	-0.3	-0.8	-0.5	-0.2	-0.1	0.2	-0.7	-0.6	-0.1	-0.3	-0.0	-0.8	-0.8
Comparative height size at age 10	0.8	4.5	23.0	4.8	-2.0	0.8	-2.2	-1.4	-2.3	-2.0	1.0	2.6	-2.0	1.3	2.4	0.9	1.3	-2.0	-0.6	-2.0	-2.0	2.8
Number of full sisters	1.1	1.3	4.2	0.2	0.8	0.1	1.4	0.5	1.0	1.0	1.5	1.8	1.0	1.5	-1.0	0.5	0.8	1.0	0.9	2.1	0.9	1.5
Suffer from ‘nerves’	0.1	0.2	0.9	0.4	0.2	0.7	0.4	-0.9	-0.3	-0.1	0.8	0.7	-0.1	0.3	0.1	0.5	0.2	-0.0	0.2	0.5	0.2	0.7
Overall health rating	0.1	0.2	1.7	-0.1	-0.1	1.3	0.2	0.8	0.2	0.0	0.3	0.5	0.1	1.0	0.1	0.2	0.3	0.2	0.4	0.1	-0.1	0.2
Chest pain or discomfort	1.6	2.3	5.8	-0.6	1.0	0.8	1.7	0.7	0.8	1.9	1.9	0.7	1.9	2.0	-1.9	2.4	1.6	1.8	1.9	0.9	1.4	0.8
Had major operations	1.1	1.3	3.9	-0.4	0.9	-0.5	1.2	1.0	0.5	0.9	2.0	1.7	0.9	1.6	-0.9	1.5	1.1	0.5	0.9	1.0	1.0	1.6
Age at last live birth	0.7	1.0	5.6	1.5	0.0	2.4	0.2	-0.0	-0.8	-0.0	1.4	1.8	-0.1	0.8	0.0	0.7	0.7	-0.4	-0.1	0.7	-0.2	1.8
Family relationship satisfaction	1.4	1.7	3.6	-0.5	1.8	-0.4	1.6	1.9	0.9	1.3	1.6	0.8	1.3	0.4	-1.3	1.4	1.5	1.3	1.1	1.3	1.8	1.3
Leg pain on walking	1.0	1.3	3.3	-1.8	1.2	0.1	1.2	0.2	1.7	1.0	-0.6	-1.2	1.1	-1.7	-1.0	-0.2	-0.1	1.5	0.8	0.7	1.4	-1.3
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	4.5	1.2	-0.8	2.1	-0.7	-1.0	-0.3	-1.0	-0.9	0.0	-1.0	-0.8	1.0	-1.4	-1.0	-0.8	-1.0	0.4	-0.6	-0.1
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.6	0.5	-0.4	0.1	-0.1	-0.1	-0.7	0.1	0.3	-0.2	0.1	0.7	-0.2	0.8	0.2	-0.2	0.1	-0.6	-0.3	0.1
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	2.5	0.6	0.4	0.0	0.7	-0.3	0.2	1.1	1.3	1.1	1.3	1.0	-1.2	1.6	1.4	1.5	1.2	1.1	0.7	1.4
Medication: Aspirin	1.4	1.8	4.1	-1.0	1.4	-0.8	1.9	1.2	0.3	1.5	1.5	0.5	1.6	0.8	-1.7	2.0	1.4	1.9	1.4	1.2	1.4	0.6
Supplements: Vitamin C	0.3	0.4	1.9	-0.6	0.2	-0.2	-0.1	0.2	-0.9	-0.0	-0.3	-1.2	-0.1	-1.4	-0.2	-0.1	-0.5	-0.2	-0.5	-0.5	0.0	-1.0
Knee pain experienced in last month	0.4	0.6	3.4	0.9	-0.2	1.3	0.5	-0.1	0.8	0.2	0.7	1.8	0.3	0.4	0.0	0.5	0.8	0.6	0.9	0.9	0.0	1.3
Hypertension (Self-reported)	1.8	5.0	17.9	4.2	-1.5	1.0	-1.1	0.9	-4.1	-1.5	1.8	1.7	-1.2	3.7	1.4	2.7	2.4	-1.1	-0.4	-2.1	-1.4	3.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	3.4	0.3	0.6	1.2	0.6	0.4	0.3	0.1	1.3	1.7	0.1	1.8	0.2	1.1	1.4	0.4	0.7	0.1	0.6	1.7
Illnesses of father: Heart disease	0.9	1.3	4.8	-1.5	0.2	-2.2	1.5	0.6	0.8	1.4	0.6	-0.5	1.4	0.5	-1.5	1.2	0.4	1.5	1.2	0.9	0.9	-0.6
Illnesses of siblings: Diabetes	0.4	0.5	1.1	-0.3	0.2	-0.2	1.1	0.8	0.5	0.6	0.8	0.8	0.7	0.4	-0.6	0.9	0.8	0.9	0.9	0.8	0.8	0.8
Smoking status: Previous	1.4	2.0	6.3	1.7	-1.9	0.3	-2.0	0.6	-2.0	-1.6	-0.7	-0.1	-1.6	0.9	1.7	0.3	-0.0	-1.6	-0.8	-2.5	-2.0	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.2	12.4	3.5	-1.9	2.0	-1.7	-0.5	-1.9	-1.6	1.1	2.1	-1.6	1.9	1.9	0.9	0.7	-1.9	-0.6	-1.7	-1.8	2.0
Whole body fat-free mass	0.2	0.9	5.1	-0.5	0.0	-1.2	0.7	-1.7	0.6	0.9	1.0	0.9	0.9	0.9	-1.0	0.3	0.1	1.1	0.1	2.3	0.5	0.8
Leg fat-free mass (right)	0.2	1.1	6.0	-1.0	0.6	-1.1	1.1	-1.1	0.9	1.2	0.9	0.7	1.2	0.6	-1.3	0.0	-0.0	1.2	0.3	2.4	0.8	0.6
Arm fat percentage (left)	0.4	1.7	4.1	1.3	-1.0	2.0	-1.7	-0.2	-1.8	-1.9	-0.7	0.1	-1.8	0.3	1.9	-1.1	-0.5	-1.6	-1.6	-0.9	-1.2	0.6
Average weekly red wine intake	0.1	0.2	0.6	-0.2	0.4	-0.5	-0.4	0.5	0.7	0.0	-0.3	-0.3	-0.0	-0.8	0.3	-0.1	0.2	-0.0	0.2	-0.7	0.5	-0.2
Handedness (chirality/laterality): Left-handed	1.7	2.0	3.7	0.1	-1.8	0.2	-1.5	-0.9	-1.3	-1.4	-1.7	-1.7	-1.4	-0.5	1.3	-1.6	-1.9	-1.6	-1.8	-1.1	-1.6	-1.6
Mood swings	0.4	0.7	3.0	0.9	-0.5	1.6	-0.2	-1.7	-1.2	-0.4	-0.6	-1.3	-0.4	-0.6	0.1	-0.4	-0.9	-0.7	-0.8	-0.4	-0.6	-0.9
Loneliness, isolation	0.5	0.8	3.0	0.2	-0.3	1.2	-0.6	-1.7	-0.4	-0.9	-0.8	-0.8	-0.9	-0.7	0.8	-1.3	-1.1	-0.8	-1.0	0.0	-0.2	-0.7
Long-standing illness, disability or infirmity	0.3	0.5	1.3	-0.6	1.1	-0.7	0.7	0.4	0.5	0.5	0.7	0.5	0.5	0.6	-0.4	0.7	1.1	0.6	0.6	-0.1	0.9	0.7
Ever had bowel cancer screening	1.3	1.5	4.1	-0.5	-0.6	-0.8	-0.6	-1.0	-1.1	-1.0	-1.8	-2.0	-1.0	-1.5	0.7	-1.3	-1.8	-0.9	-1.5	-0.5	-1.0	-2.0
Diabetes diagnosed by doctor	3.7	6.1	15.6	0.1	2.4	-0.3	1.9	3.5	1.6	1.5	3.3	4.0	1.5	2.8	-1.1	2.9	3.7	1.6	2.6	1.1	2.2	3.9
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	4.3	-1.6	1.8	-0.7	2.0	0.7	0.5	1.7	1.0	-0.2	1.7	-0.2	-2.1	0.7	0.6	1.6	1.0	1.7	1.7	0.1
Friendships satisfaction	0.9	1.2	3.7	-1.7	1.0	-0.5	0.6	-0.1	1.0	0.7	-0.9	-1.8	0.6	-1.9	-0.8	-1.3	-1.1	0.5	-0.4	1.0	1.0	-1.5
Qualifications: nursing, teaching	2.5	3.9	6.3	-2.3	2.5	-2.3	2.2	2.5	2.2	2.4	1.1	0.1	2.5	0.1	-2.5	1.2	1.3	2.5	1.9	1.6	2.5	0.2
Commuting to job workplace: Walk	0.8	0.8	2.7	1.0	-0.6	0.5	-1.3	0.2	-0.4	-1.3	0.1	0.8	-1.4	-0.3	1.6	-0.4	0.1	-1.4	-0.7	-1.3	-0.7	0.8
Eye problems/disorders: Cataract	0.5	0.6	2.5	0.1	-0.4	-0.0	-0.4	-1.6	-0.0	-0.5	-0.9	-0.3	-0.5	-1.0	0.5	-1.5	-1.1	-0.4	-1.0	0.7	-0.5	-0.5
Mouth/teeth dental problems: Mouth ulcers	2.0	3.2	9.2	-3.0	1.0	-2.8	1.8	-0.7	2.0	2.2	-0.3	-1.6	2.2	-1.7	-2.4	0.1	-0.4	2.1	1.0	1.8	1.7	-1.7
Medication for cholesterol	1.1	1.7	7.8	-1.4	1.7	-0.5	1.1	-0.0	2.8	1.7	0.6	0.6	1.5	-1.3	-1.6	-0.1	0.1	1.2	1.4	1.6	1.4	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	3.2	-1.8	0.6	-0.3	0.5	-0.4	0.6	0.4	-0.9	-1.6	0.4	-1.7	-0.5	-0.5	-0.8	0.3	-0.1	-0.3	0.5	-1.7
Back pain experienced in last month	0.0	0.0	0.2	0.2	0.1	0.4	-0.0	0.1	0.2	0.2	-0.0	0.0	0.3	0.2	-0.2	0.2	0.4	0.5	0.3	0.1	0.1	0.0
Mineral and other dietary supplements	0.7	1.0	4.0	-2.0	0.8	0.3	0.9	0.4	0.9	0.9	-0.6	-1.5	0.9	-1.0	-1.1	-0.5	-0.8	0.9	0.2	0.9	0.8	-1.5
Breast cancer (self-reported)	0.1	0.2	0.6	0.2	0.5	0.8	0.2	-0.3	0.8	0.5	0.0	0.3	0.5	-0.2	-0.3	-0.2	0.1	0.5	0.4	0.5	0.2	-0.1
Asthma (self-reported)	0.7	1.4	4.3	0.4	0.9	0.8	0.8	2.1	0.7	0.9	1.0	1.2	1.0	2.0	-0.6	1.3	1.7	1.1	1.6	-0.0	0.6	1.2
Osteoporosis (self-reported)	0.6	0.8	3.0	-0.3	1.1	-0.9	1.6	-0.4	0.3	0.8	1.1	0.4	0.9	0.2	-1.1	0.3	0.4	0.9	0.5	1.7	1.2	0.6
Osteoarthritis (self-reported)	1.0	1.3	4.3	-1.6	1.5	0.6	1.4	-0.5	2.1	1.0	0.5	0.7	1.0	-0.7	-0.9	-0.1	0.4	1.3	1.0	1.8	1.6	0.3
Medication: Aspirin	1.6	2.1	4.4	-1.2	1.7	-0.6	2.0	1.5	0.6	1.6	1.4	0.4	1.8	0.6	-1.8	1.9	1.4	2.1	1.5	1.3	1.6	0.5
Medication: Gliclazide	0.4	0.4	1.4	-1.1	0.7	-1.2	0.7	0.2	0.8	0.5	0.4	0.2	0.5	-0.1	-0.5	0.4	0.7	0.8	0.6	0.5	1.0	0.3
Illnesses of father: None of the above (group 1)	0.2	0.2	0.8	-0.1	0.8	0.4	-0.3	0.5	0.3	-0.3	-0.4	-0.1	-0.4	-0.9	0.3	-0.7	-0.3	-0.5	-0.3	-0.5	0.2	-0.2
Smoking status: Current	2.2	3.5	8.9	-2.3	2.1	-0.4	2.9	0.5	1.8	2.6	1.1	-0.7	2.6	-0.5	-3.0	1.1	0.6	2.5	1.6	2.1	2.4	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.9	6.1	11.9	-2.6	3.0	-1.7	3.0	1.3	3.5	3.1	2.0	1.1	3.0	0.2	-3.1	1.4	1.6	3.0	2.6	3.0	3.3	0.8
Whole body water mass	0.2	1.1	5.6	-0.6	0.1	-1.1	0.9	-1.6	0.7	1.1	1.1	0.9	1.1	1.1	-1.2	0.5	0.2	1.2	0.3	2.4	0.6	0.8
Leg predicted mass (right)	0.2	1.0	5.7	-1.0	0.6	-1.1	1.0	-1.2	0.9	1.1	0.9	0.7	1.1	0.5	-1.2	0.0	-0.1	1.2	0.2	2.4	0.7	0.5
Arm fat mass (left)	0.3	1.4	2.7	1.2	-1.2	1.4	-1.5	-1.0	-1.5	-1.6	-0.5	0.3	-1.6	0.2	1.6	-1.1	-0.6	-1.3	-1.5	-0.5	-1.2	0.6
Number of self-reported non-cancer illnesses	0.8	1.4	4.0	0.8	0.7	1.2	1.1	0.8	-0.6	0.6	1.7	1.4	0.8	2.0	-0.7	2.0	1.9	0.8	1.3	0.2	0.4	1.6
Average weekly champagne plus white wine intake	0.7	0.9	2.8	-1.4	0.4	1.0	0.2	-1.1	0.5	0.4	-1.1	-1.3	0.4	-1.7	-0.7	-1.4	-1.1	0.5	-0.4	0.9	0.2	-1.3
Miserableness	0.7	1.2	2.6	-1.0	1.5	0.2	1.4	-1.0	1.4	1.4	0.6	-0.2	1.4	-0.5	-1.6	0.4	0.4	1.5	0.8	1.5	1.6	-0.1
Guilty feelings	1.6	2.4	5.5	-0.8	2.1	0.1	1.4	2.3	2.1	1.5	1.8	1.5	1.4	1.1	-1.3	1.5	1.8	1.0	1.8	0.5	2.0	1.3
Wears glasses or contact lenses	0.2	0.3	1.4	0.3	-0.5	-0.6	-0.4	-0.7	-1.2	-0.3	-0.4	-0.5	-0.3	-0.3	0.2	0.4	0.0	-0.3	-0.1	-1.0	-0.6	-0.2
Ever taken oral contraceptive pill	0.2	0.2	0.7	0.7	-0.4	-0.9	-0.4	0.5	-0.5	-0.3	0.1	0.0	-0.3	0.6	0.3	0.3	-0.0	-0.4	-0.2	-0.6	-0.4	-0.0
Hearing aid user	3.4	3.8	8.0	0.9	-2.4	-0.2	-2.4	-1.3	-1.9	-1.7	-2.6	-2.8	-1.7	-0.9	1.5	-1.5	-2.0	-1.9	-1.9	-2.4	-2.2	-2.5
Mother’s age at death	2.1	2.7	7.6	2.5	-2.8	0.5	-2.4	-1.2	-2.2	-2.0	-1.1	-0.2	-1.9	0.4	1.9	-0.6	-0.7	-1.6	-1.4	-1.4	-2.2	0.1
Financial situation satisfaction	0.5	0.7	2.5	-1.2	1.0	0.3	1.0	0.7	0.0	1.0	-0.2	-1.6	0.9	-0.5	-1.2	-0.1	-0.5	0.6	-0.0	0.2	0.5	-1.3
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.3	1.5	-1.1	0.7	-0.7	0.2	-1.4	-0.7	-0.1	-0.3	-0.7	0.2	0.6	0.6	0.2	-0.8	-0.3	-1.3	-0.9	0.0
Commuting to job workplace: Public transport	0.3	0.4	1.2	-0.7	-0.2	-0.7	0.6	-0.7	0.1	0.5	-0.4	-0.9	0.6	-0.0	-0.8	-0.4	-0.6	0.6	-0.2	1.1	0.1	-0.9
Eye problems/disorders: Glaucoma	0.8	1.0	3.1	0.3	1.0	0.3	1.5	0.2	0.1	1.3	1.2	0.4	1.3	0.9	-1.4	1.8	0.9	1.0	0.8	0.9	0.6	0.4
Medication: Blood pressure	1.4	2.7	10.9	2.9	-1.6	0.3	-0.7	0.4	-3.3	-1.2	0.9	0.9	-1.0	2.6	1.1	2.1	1.6	-0.8	-0.4	-1.8	-1.3	1.8
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.9	-0.4	0.6	0.7	0.9	-0.1	0.2	0.3	-0.1	-0.2	0.3	-0.4	-0.5	-0.6	-0.3	0.4	-0.2	0.9	0.4	-0.2
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.9	0.7	0.3	0.3	-0.0	0.8	-0.2	-0.3	0.9	1.4	-0.3	0.5	0.5	0.8	1.1	-0.3	0.3	-0.4	0.3	1.4
High cholesterol (Self-reported)	3.0	5.4	10.1	-1.5	1.9	-0.1	3.2	1.7	1.6	2.5	2.8	1.8	2.6	3.1	-2.5	2.5	2.3	2.8	2.4	2.8	2.3	1.8
Medication: Bendroflumethiazide	1.3	2.0	6.7	0.8	0.4	-1.3	1.1	2.5	-1.6	0.7	1.5	0.3	0.9	2.4	-1.0	2.6	2.0	1.0	1.0	-0.5	0.5	1.1
Medication: Paracetamol	1.1	1.7	4.5	1.4	0.9	1.3	0.8	1.4	-0.6	0.7	1.8	1.7	0.7	1.4	-0.7	2.0	2.1	0.6	0.9	-0.2	0.6	2.1
Medication: Lisinopril	0.3	0.4	1.2	0.2	0.7	0.8	0.7	1.1	-0.7	0.5	0.9	0.3	0.5	1.0	-0.6	0.9	0.8	0.2	0.3	-0.1	0.2	0.6
Medication: Atorvastatin	3.4	4.2	8.4	-1.4	2.3	0.1	2.9	1.3	1.3	2.4	2.5	1.4	2.5	1.6	-2.5	1.9	1.8	2.5	1.9	2.6	2.4	1.5
Illnesses of father: High blood pressure	1.2	1.5	5.9	2.4	-2.0	0.6	-1.3	-0.6	-2.1	-1.3	-0.5	0.1	-1.1	-0.1	1.4	0.4	0.1	-1.0	-0.7	-1.4	-1.7	0.4
Alcohol drinker status: Never	1.7	2.0	3.5	-0.9	1.0	-1.2	1.9	0.4	1.2	1.6	1.6	1.2	1.7	1.7	-1.6	1.5	1.2	1.7	1.6	1.8	1.2	0.9
Ever smoked	0.7	1.3	4.2	1.6	-1.7	-0.3	-1.4	-0.2	-1.9	-1.0	-0.4	-0.6	-1.0	0.8	0.8	0.7	0.0	-1.1	-0.7	-2.0	-1.6	-0.3
Basal metabolic rate	0.1	0.5	3.1	0.3	-0.5	-0.5	0.0	-1.7	-0.1	0.2	0.8	1.0	0.2	1.0	-0.2	0.1	-0.0	0.4	-0.3	1.6	-0.1	1.0
Leg fat percentage (left)	1.5	5.5	10.2	2.9	-2.8	2.8	-2.9	-1.6	-3.2	-3.1	-1.3	0.2	-3.0	0.8	3.1	-1.5	-0.9	-2.7	-2.4	-1.9	-2.7	0.7
Arm fat-free mass (left)	0.1	0.6	5.4	0.5	-1.1	-0.2	-0.3	-2.3	-0.3	-0.1	0.4	0.7	-0.1	0.9	0.1	-0.2	-0.4	0.1	-0.6	1.3	-0.6	0.6
Number of operations (self-reported)	0.2	0.3	1.9	0.5	-0.7	0.6	-0.0	-1.4	-1.0	-0.2	0.0	-0.5	-0.2	0.2	0.0	-0.0	-0.5	-0.3	-0.8	0.1	-0.4	-0.3
Average weekly beer plus cider intake	2.8	4.0	8.3	2.9	-2.8	1.1	-2.7	-0.5	-2.5	-2.6	-1.0	0.1	-2.6	1.1	2.7	-0.4	-0.5	-2.5	-1.4	-2.6	-2.6	0.4
Irritability	0.3	0.6	3.3	1.8	-0.6	1.7	-0.5	-0.6	-1.0	-0.4	0.3	0.3	-0.3	0.2	0.4	0.7	0.5	-0.4	-0.0	-0.8	-0.5	0.6
Risk taking	0.4	0.6	2.7	0.6	-0.9	0.9	-0.5	-0.8	-1.7	-0.7	-0.6	-1.0	-0.6	0.3	0.4	0.1	-0.3	-0.5	-0.5	-1.0	-0.9	-0.5
Ever had prostate specific antigen (PSA) test	5.2	6.0	9.8	-3.0	3.1	-1.9	3.1	2.8	2.6	2.9	1.7	0.9	2.9	0.9	-2.8	2.1	2.3	3.0	2.8	1.7	3.0	0.6
Fractured/broken bones in last 5 years	1.0	1.3	3.5	-0.3	0.9	-0.6	1.3	1.1	0.5	0.9	1.6	1.1	1.0	1.6	-0.9	1.9	1.4	1.0	1.4	0.6	0.9	1.0
Age started oral contraceptive pill	0.2	0.2	1.3	0.0	0.3	0.1	0.4	-0.8	0.1	0.1	-0.2	-0.5	0.1	-1.2	-0.2	-0.7	-0.5	0.1	-0.4	0.7	0.4	-0.3
Diastolic blood pressure, automated reading	3.1	9.6	39.4	6.3	-3.2	1.3	-3.0	-2.9	-5.9	-3.1	0.5	1.1	-2.9	2.5	3.0	1.0	0.8	-3.0	-2.5	-2.9	-3.2	2.7
Ever depressed for a whole week	0.6	0.7	2.0	-0.3	0.2	-0.0	-0.6	-0.3	-1.0	-0.9	-0.8	-1.4	-0.9	-1.1	0.8	-0.9	-0.9	-0.9	-1.4	-0.7	-0.1	-0.9
Unable to work because of sickness or disability	0.3	0.4	1.8	0.7	0.7	1.3	-0.0	-0.2	-0.2	-0.2	0.6	0.8	-0.2	0.1	0.3	0.4	0.9	-0.3	0.0	-0.3	0.5	1.2
Commuting to job workplace: Cycle	0.7	0.8	3.3	0.8	-0.8	0.2	-0.9	-0.8	-0.2	-0.8	-1.1	-0.9	-0.9	-1.8	0.9	-0.8	-0.8	-0.9	-0.8	-1.1	-0.7	-0.9
Myopia	0.1	0.1	0.4	-0.4	0.5	-0.1	0.5	0.2	-0.1	0.4	0.3	0.0	0.5	0.6	-0.4	0.4	0.3	0.4	0.3	0.5	0.2	0.2
Vascular/heart problems diagnosed by doctor	1.3	3.4	14.6	-3.0	1.2	-0.8	0.3	-0.3	3.5	0.5	-1.8	-1.1	0.3	-3.8	-0.3	-3.0	-2.3	0.2	-0.2	1.3	1.0	-2.3
Cholesterol lowering medication	0.6	0.9	3.1	-1.2	0.7	-0.4	1.8	0.7	0.5	0.9	0.8	0.0	1.1	0.4	-1.0	1.1	0.9	1.5	0.8	1.1	1.4	0.3
Medication: Omeprazole (e.g. Zanprol)	0.4	0.4	1.4	-1.2	1.1	0.6	0.8	0.2	1.2	0.5	-0.1	-0.3	0.5	-0.5	-0.4	-0.3	-0.3	0.6	0.4	0.8	0.8	-0.7
Pain experienced in last month	0.3	0.4	1.3	-0.8	-0.0	-0.4	-0.5	-0.3	-1.0	-0.5	-0.6	-1.1	-0.6	-0.2	0.3	-0.8	-0.9	-0.9	-1.1	-0.5	-0.2	-0.6
Supplements: Calcium	1.9	2.1	5.2	2.3	-1.2	1.4	-1.9	-1.1	-1.6	-1.6	-0.9	-0.1	-1.6	-1.4	1.7	-1.4	-1.0	-1.7	-1.6	-1.2	-1.7	-0.1
Basal cell carcinoma (self-reported)	0.7	0.8	1.9	-0.3	-0.4	1.1	-1.0	1.0	0.2	-0.6	-1.2	-0.6	-0.7	-1.0	0.8	-1.4	-1.2	-0.8	-0.6	-0.9	-0.9	-1.1
Heart attack/myocardial infarction (self-reported)	0.7	0.9	3.1	-1.8	0.4	-0.6	0.7	-1.1	0.8	0.8	-0.7	-1.6	0.7	-1.1	-1.0	-0.7	-1.1	0.7	0.1	0.7	0.4	-1.7
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	3.5	-1.9	1.2	1.2	1.2	-0.2	1.6	0.8	0.5	0.6	0.7	-0.5	-0.7	-0.3	0.1	0.8	0.8	1.4	1.1	0.2
Heart disease (siblings)	0.9	1.1	3.8	1.0	-0.8	0.5	-1.0	0.5	-1.0	-1.3	-1.1	-0.5	-1.3	-1.3	1.4	-0.6	-0.1	-1.2	-0.9	-2.0	-0.8	-0.2
Alcohol drinker status: Previous	2.7	3.1	6.3	1.5	-1.8	1.5	-2.3	-0.5	-1.6	-2.1	-1.9	-1.0	-2.1	-1.8	2.3	-1.3	-1.3	-2.0	-1.4	-2.5	-2.1	-1.2
Pack years of smoking	0.3	0.5	3.8	0.6	-0.6	0.8	0.1	-1.9	-0.8	-0.1	-0.2	-0.8	-0.1	-0.9	-0.1	-0.4	-0.6	-0.1	-0.6	0.3	-0.4	-0.5
Impedance of whole body	5.1	25.8	74.4	8.6	-5.4	3.9	-6.7	-1.9	-6.1	-6.4	-1.7	1.4	-6.5	0.3	7.1	-0.9	-0.3	-6.6	-3.4	-7.3	-5.9	1.9
Leg fat mass (left)	0.8	3.1	5.5	2.2	-2.1	1.8	-2.2	-1.7	-2.3	-2.3	-0.6	0.6	-2.2	0.9	2.3	-1.2	-0.7	-2.0	-2.0	-0.8	-1.9	1.0
Arm predicted mass (left)	0.1	0.6	4.0	0.6	-1.0	-0.2	-0.1	-2.0	-0.3	-0.1	0.6	1.0	0.0	1.2	0.0	0.1	-0.0	0.2	-0.4	1.3	-0.5	1.0