[Hub]/) : Traits : Systolic blood pressure, automated reading : ← →

chr17:6,397,773-8,173,767

Best TWAS P=5.6e-11 · Best GWAS P=5.2e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ACADVL	0.09	0.06	bslmm	467	0.07	2.1e-08	-6.0	-5.5	3.0e-08	0.86	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SLC2A4	0.08	0.06	lasso	2	0.08	1.2e-09	-4.4	5.9	4.6e-09	-0.58	0.10	0.90	FALSE
3	GTEx	Artery Aorta	ACADVL	0.10	0.09	lasso	3	0.10	2.4e-06	-5.8	-5.9	3.3e-09	0.87	0.02	0.98	FALSE
4	GTEx	Artery Tibial	ACADVL	0.12	0.10	enet	3	0.10	2.7e-08	-6.2	-6.3	3.6e-10	0.97	0.00	1.00	FALSE
5	GTEx	Cells Transformed fibroblasts	TNFSF12	0.25	0.22	lasso	8	0.20	7.4e-15	5.7	5.6	2.8e-08	-0.04	0.05	0.95	FALSE
6	GTEx	Esophagus Mucosa	CTDNEP1	0.21	0.17	lasso	6	0.17	2.3e-11	-4.4	5.1	3.0e-07	-0.79	0.10	0.90	FALSE
7	GTEx	Muscle Skeletal	DLG4	0.12	0.05	lasso	4	0.05	2.3e-05	-5.8	6.0	1.6e-09	-0.95	0.00	1.00	TRUE
8	GTEx	Skin Sun Exposed Lower leg	DVL2	0.10	0.03	lasso	2	0.02	1.5e-02	-5.8	-5.9	4.8e-09	0.86	0.02	0.98	FALSE
9	GTEx	Whole Blood	ACADVL	0.07	0.04	lasso	2	0.03	3.4e-04	-6.0	-5.8	5.4e-09	0.94	0.01	0.99	TRUE
10	METSIM	Adipose	SENP3	0.06	0.03	lasso	3	0.02	4.9e-04	5.4	-6.6	5.6e-11	0.24	0.17	0.67	TRUE
11	NTR	Blood	TNFSF12	0.06	0.07	bslmm	462	0.07	9.4e-23	5.4	6.0	1.6e-09	0.01	0.09	0.91	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	SLC2A4	0.08	0.08	enet	9	0.08	5.5e-11	-6.1	6.0	2.3e-09	-0.80	0.01	0.99	TRUE
13	ROSMAP	Brain Pre-frontal Cortex	CLDN7	0.07	0.06	lasso	4	0.05	3.9e-07	-5.9	-5.8	6.8e-09	0.85	0.03	0.97	FALSE
14	The Cancer Genome Atlas	Breast Invasive Carcinoma	C17orf81	0.04	0.05	blup	43	0.06	4.0e-12	-4.3	-5.2	1.7e-07	0.73	0.93	0.06	FALSE
15	The Cancer Genome Atlas	Breast Invasive Carcinoma	DULLARD	0.03	0.07	enet	13	0.07	5.8e-15	-4.4	5.4	5.1e-08	-0.84	0.42	0.58	TRUE
16	The Cancer Genome Atlas	Colon Adenocarcinoma	TNFSF12-TNFSF13	0.07	0.05	lasso	3	0.02	1.9e-02	5.4	5.5	4.2e-08	0.00	0.01	0.90	FALSE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DULLARD	0.03	0.03	blup	42	0.03	9.3e-05	-5.9	6.0	1.9e-09	-0.87	0.02	0.97	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TNFSF12	0.04	0.01	enet	9	0.01	4.3e-02	5.4	-6.0	2.7e-09	0.01	0.01	0.82	FALSE
19	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C17orf81	0.11	0.13	blup	43	0.13	8.7e-08	-4.4	-5.2	2.2e-07	0.74	0.32	0.68	FALSE
20	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DULLARD	0.13	0.11	blup	42	0.13	8.7e-08	-4.4	5.7	9.8e-09	-0.87	0.04	0.96	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	ACADVL	0.03	0.03	blup	37	0.04	5.5e-05	-6.1	-5.8	7.2e-09	0.88	0.01	0.98	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	C17orf81	0.04	0.05	enet	8	0.04	1.2e-05	-6.1	-5.7	1.1e-08	0.66	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Brain Lower Grade Glioma	SLC2A4	0.09	0.04	lasso	4	0.06	7.2e-08	-5.9	6.0	2.1e-09	-0.78	0.00	1.00	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	DULLARD	0.04	0.06	blup	42	0.08	3.3e-09	-4.3	5.2	2.3e-07	-0.81	0.15	0.85	FALSE
25	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C17orf81	0.06	0.12	lasso	8	0.12	6.3e-14	-5.8	-5.6	2.5e-08	0.82	0.06	0.94	FALSE
26	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DULLARD	0.10	0.10	enet	8	0.10	7.7e-05	-5.8	5.4	7.5e-08	-0.80	0.05	0.92	FALSE
27	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	DULLARD	0.07	0.02	blup	42	0.06	2.3e-03	4.8	5.9	4.8e-09	-0.87	0.02	0.80	FALSE
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	DULLARD	0.05	0.08	blup	42	0.07	1.7e-07	-4.4	5.6	2.3e-08	-0.88	0.07	0.93	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	SHBG	0.04	0.01	blup	60	0.03	5.4e-04	4.1	5.2	2.5e-07	-0.05	0.01	0.60	FALSE
30	The Cancer Genome Atlas	Prostate Adenocarcinoma	TNFSF12-TNFSF13	0.03	0.00	lasso	4	0.01	2.9e-02	5.7	6.0	1.8e-09	-0.01	0.01	0.76	TRUE
31	The Cancer Genome Atlas	Thyroid Carcinoma	SHBG	0.04	0.00	blup	59	0.02	4.4e-03	5.6	5.4	6.0e-08	-0.05	0.01	0.81	FALSE