TWAS hub - VNN2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0950	0.0380	3.2e-03	0.080	NA	0.025	NA	0.059	4.2e-07	NA	3.6e-03	NA	1.5e-05
2	GTEx	Breast Mammary Tissue (Female)	0.1310	0.0772	4.5e-02	-0.006	NA	-0.001	NA	-0.001	5.1e-01	NA	3.6e-01	NA	3.5e-01
3	GTEx	Nerve Tibial	0.2185	0.0671	8.1e-04	0.035	NA	0.046	NA	-0.003	1.6e-03	NA	3.1e-04	NA	6.8e-01
4	GTEx	Whole Blood	0.2400	0.0430	1.8e-11	0.134	NA	0.166	NA	0.176	2.5e-12	NA	4.3e-15	NA	4.9e-16
5	METSIM	Adipose	0.0767	0.0246	1.3e-05	0.059	0.036	0.040	0.041	0.051	3.5e-09	3.0e-06	1.0e-06	7.5e-07	3.5e-08
6	NTR	Blood	0.1545	0.0264	0.0e+00	0.096	0.098	0.107	0.113	0.106	2.4e-29	7.1e-30	1.0e-32	1.3e-34	2.3e-32
7	ROSMAP	Brain Pre-frontal Cortex	0.0538	0.0265	9.8e-03	0.015	0.013	0.016	0.020	0.017	4.8e-03	6.8e-03	3.0e-03	1.1e-03	2.5e-03
8	YFS	Blood	0.3536	0.0335	0.0e+00	0.381	0.358	0.389	0.389	0.391	6.5e-134	9.7e-124	4.5e-137	3.7e-137	2.7e-138
9	TCGA	Bladder Urothelial Carcinoma	0.0570	0.0300	8.4e-03	0.031	0.013	-0.003	NA	0.008	1.1e-03	2.4e-02	7.2e-01	NA	6.2e-02
10	TCGA	Breast Invasive Carcinoma	0.0728	0.0241	7.7e-12	0.065	0.068	0.061	NA	0.067	3.1e-13	7.9e-14	1.6e-12	NA	1.2e-13
11	TCGA	Colon Adenocarcinoma	0.0790	0.0360	2.6e-03	0.060	0.037	0.042	NA	0.052	2.3e-04	3.2e-03	1.7e-03	NA	5.4e-04
12	TCGA	Head and Neck Squamous Cell Carcinoma	0.0325	0.0157	2.0e-03	0.022	0.014	0.012	NA	0.015	1.4e-03	9.9e-03	1.6e-02	NA	7.1e-03
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0935	0.0287	2.0e-10	0.098	0.094	0.083	NA	0.087	3.9e-11	9.2e-11	1.2e-09	NA	4.8e-10
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0790	0.0360	1.2e-03	0.052	0.047	0.045	NA	0.034	5.7e-04	1.1e-03	1.4e-03	NA	5.0e-03
15	TCGA	Brain Lower Grade Glioma	0.0528	0.0213	4.7e-05	0.053	0.053	0.039	NA	0.046	1.2e-06	1.1e-06	2.8e-05	NA	5.6e-06
16	TCGA	Liver Hepatocellular Carcinoma	0.1260	0.0590	1.9e-03	0.061	0.024	0.043	NA	0.069	8.0e-04	2.5e-02	4.4e-03	NA	3.6e-04
17	TCGA	Lung Adenocarcinoma	0.1193	0.0371	5.1e-11	0.111	0.092	0.109	NA	0.107	7.0e-13	6.2e-11	1.2e-12	NA	1.7e-12
18	TCGA	Lung Squamous Cell Carcinoma	0.1286	0.0454	3.0e-10	0.096	0.091	0.102	NA	0.106	5.1e-11	1.8e-10	1.3e-11	NA	4.7e-12
19	TCGA	Ovarian Serous Cystadenocarcinoma	0.1320	0.0570	3.0e-05	0.109	0.029	0.063	NA	0.083	8.2e-08	4.8e-03	4.2e-05	NA	2.9e-06
20	TCGA	Pheochromocytoma and Paraganglioma	0.1720	0.0740	3.9e-04	0.034	0.062	0.097	NA	0.050	1.7e-02	1.9e-03	1.1e-04	NA	4.7e-03
21	TCGA	Prostate Adenocarcinoma	0.1927	0.0548	2.2e-15	0.166	0.152	0.160	NA	0.158	5.1e-17	1.2e-15	1.9e-16	NA	2.8e-16
22	TCGA	Soft Tissue Sarcoma	0.2400	0.0630	1.1e-10	0.146	0.183	0.186	NA	0.207	5.6e-09	4.5e-11	3.1e-11	NA	1.8e-12
23	TCGA	Thyroid Carcinoma	0.1020	0.0400	8.9e-07	0.061	0.069	0.055	NA	0.054	1.4e-06	2.6e-07	4.4e-06	NA	5.7e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23
Heel T-Score	6.8	54.2	104.0	-6.6	-5.1	-4.3	-8.0	-10.2	-3.8	-5.6	-7.5	-10.1	-9.9	-7.5	-7.2	-9.2	-8.2	-7.2	0.3	-8.0	-7.8	-6.9	-4.2	-7.6	-7.3	-8.6
Heel bone mineral density (BMD) T-score, automated (left)	5.9	13.4	26.5	-3.8	-2.5	-2.1	-4.0	-5.1	-1.5	-3.4	-3.7	-4.9	-5.2	-3.7	-3.2	-4.0	-3.3	-3.6	0.4	-3.9	-4.0	-3.6	-2.7	-3.7	-4.0	-4.1
Heel bone mineral density (BMD) T-score, automated (right)	5.8	13.2	26.1	-3.5	-2.1	-2.0	-3.7	-5.1	-1.6	-3.4	-3.6	-4.8	-5.1	-3.6	-3.2	-4.3	-3.3	-3.7	0.3	-3.9	-3.9	-3.8	-2.7	-3.7	-4.0	-4.4
Qualifications: CSEs or equivalent	5.7	7.5	12.7	3.3	3.1	2.1	3.4	3.3	1.8	2.0	2.8	2.8	2.8	3.1	2.4	2.2	1.6	2.7	-2.8	2.7	2.4	3.6	1.9	3.0	3.4	2.6
Knee pain experienced in last month	5.1	8.0	14.3	3.2	2.9	1.4	3.5	3.1	2.1	2.5	3.2	3.8	3.4	3.2	2.7	2.4	2.1	3.1	-0.8	3.1	3.1	2.8	2.2	3.1	3.0	2.5
Had major operations	4.7	5.6	9.1	-2.5	-2.2	-0.4	-3.0	-2.3	-2.2	-2.4	-2.8	-2.1	-2.8	-2.8	-2.7	-2.0	-1.3	-2.3	0.6	-2.7	-2.9	-2.4	-1.9	-2.6	-2.7	-2.5
Lung cancer (father)	4.4	5.2	9.0	-2.7	-2.6	-1.7	-2.3	-2.3	-1.1	-0.9	-2.0	-1.2	-2.5	-2.2	-2.4	-2.7	-2.4	-1.4	1.9	-2.7	-2.4	-2.5	-2.7	-1.9	-3.0	-2.9
Handedness (chirality/laterality): Left-handed	4.1	4.9	7.7	-1.8	-1.5	-1.7	-2.7	-2.2	-2.3	-2.5	-2.7	-2.1	-2.3	-2.8	-2.4	-1.7	-0.6	-2.8	0.4	-2.2	-2.4	-2.4	-2.6	-2.7	-2.2	-2.2
Illnesses of father: High blood pressure	3.9	4.8	8.5	2.4	2.5	1.5	1.9	2.9	1.6	1.6	1.9	2.8	2.6	2.1	2.3	2.6	2.7	1.9	-1.2	2.2	2.0	2.2	1.3	2.3	2.3	2.5
Illnesses of father: Heart disease	3.4	4.7	8.9	1.9	2.6	1.7	2.3	3.0	2.1	3.0	2.4	1.7	2.0	2.5	2.4	2.1	1.8	1.1	-0.8	2.1	2.1	2.5	1.9	2.5	2.4	1.6
Number of self-reported non-cancer illnesses	3.3	5.8	11.4	2.8	2.3	1.8	2.3	2.2	2.7	3.4	2.3	2.2	3.0	2.5	3.2	2.2	2.1	2.0	-0.6	2.5	2.7	1.6	2.2	2.5	2.4	2.2
Falls in the last year	3.2	4.3	6.9	2.3	1.1	1.2	1.9	2.6	2.5	2.3	2.4	2.5	2.3	2.2	1.9	2.0	1.9	1.8	1.2	2.5	2.5	1.2	1.9	2.5	1.5	2.2
Fractured/broken bones in last 5 years	2.9	3.8	6.9	2.6	1.9	1.9	1.9	2.3	1.6	1.7	1.9	1.7	2.0	2.0	2.0	1.7	0.6	2.1	-1.2	1.8	1.7	2.5	1.7	2.2	2.3	2.0
Bipolar Disorder (2018)	2.8	4.4	7.9	-1.8	-2.2	-1.6	-2.2	-2.3	-1.0	-1.7	-2.2	-2.6	-2.7	-2.3	-2.8	-2.2	-2.2	-1.9	1.3	-2.2	-2.1	-2.2	-0.5	-2.1	-2.3	-2.2
LDL Cholesterol	2.8	4.5	11.4	0.5	0.4	-1.1	2.0	2.5	3.1	1.1	2.8	2.9	2.3	2.6	1.8	1.5	0.4	3.4	2.2	2.4	2.5	1.3	1.2	2.8	1.0	2.1
Sensitivity / hurt feelings	2.8	4.7	8.2	-2.4	-2.6	-1.5	-2.1	-2.3	-1.2	-2.3	-2.2	-1.9	-2.1	-2.4	-2.0	-2.0	-1.6	-1.7	2.5	-1.8	-2.0	-2.9	-2.4	-2.4	-2.8	-2.0
Diastolic blood pressure, automated reading	2.8	8.6	16.5	2.5	2.3	2.1	2.9	3.1	2.9	2.2	3.3	4.1	3.7	3.3	2.4	3.2	3.2	3.1	-0.1	3.7	3.3	2.3	2.4	3.2	2.6	3.1
Hypothyroidism (self reported)	2.7	6.3	12.4	3.2	3.5	2.4	2.5	2.2	1.6	2.8	2.4	0.8	2.1	2.5	1.4	3.3	2.5	1.1	-2.0	2.8	2.4	3.0	2.6	2.3	3.1	2.9
Medication: Amlodipine	2.7	3.7	6.4	-2.0	-1.6	-2.5	-1.6	-2.5	-0.8	-1.9	-1.9	-2.2	-2.5	-2.0	-1.2	-2.0	-1.5	-2.1	1.1	-1.8	-1.9	-2.3	-1.3	-2.0	-2.3	-2.2
Bipolar Disorder (2011)	2.6	2.6	5.3	-1.4	-1.1	-1.0	-1.9	-2.0	-1.2	-1.4	-1.9	-1.6	-1.9	-1.9	-2.3	-1.4	-0.5	-1.7	0.0	-1.7	-1.9	-1.7	-0.7	-1.9	-1.6	-1.7
Chronic bronchitis/emphysema (father)	2.5	2.9	7.2	-1.5	-2.0	-2.7	-1.4	-2.2	-0.9	-1.5	-1.7	-1.7	-1.8	-1.7	-1.8	-1.9	-1.9	-0.9	0.5	-1.8	-1.7	-1.9	-1.0	-1.7	-1.9	-1.6
Hair/balding pattern: Pattern 2	2.5	3.1	6.4	-1.4	-0.5	-0.7	-2.0	-2.1	-2.5	-2.2	-2.2	-1.4	-2.2	-2.0	-1.6	-1.3	-0.2	-2.1	-1.3	-2.0	-2.4	-1.4	-0.7	-2.2	-1.6	-1.9
Illnesses of siblings: Diabetes	2.5	3.1	7.5	-1.4	-1.1	-1.0	-1.9	-2.7	-2.1	-1.6	-2.0	-2.4	-1.8	-2.0	-2.1	-1.8	-2.1	-0.9	-0.7	-1.9	-1.8	-1.8	0.0	-2.1	-1.6	-1.5
Pulse rate, automated reading	2.0	6.6	13.5	2.9	3.1	2.2	2.5	2.7	2.0	3.0	2.5	2.2	2.6	2.5	2.5	3.0	3.7	1.2	-0.8	3.1	2.8	2.3	1.5	2.6	2.9	2.7
Rheumatoid Arthritis	1.9	2.6	6.4	1.6	2.2	0.8	1.0	1.6	0.1	1.7	1.4	1.5	2.2	1.5	1.1	1.8	2.5	0.7	-1.8	1.6	1.4	1.6	2.0	1.3	1.9	1.6
Supplements: Zinc	1.9	2.1	4.9	-1.2	-1.8	-0.2	-1.9	-1.4	-2.2	-1.2	-1.8	-0.5	-1.1	-1.7	-1.2	-1.8	-1.2	-1.0	0.1	-1.9	-1.5	-1.5	-0.5	-1.7	-1.3	-1.7
Ever taken oral contraceptive pill	1.9	2.1	7.2	-1.5	-0.9	-0.9	-1.3	-1.7	-0.9	-2.7	-1.3	-1.1	-1.8	-1.5	-1.4	-1.6	-1.1	-1.0	1.2	-1.2	-1.3	-1.8	-1.0	-1.4	-1.8	-1.5
Supplements: Calcium	1.8	2.0	5.6	-1.0	-0.9	-1.0	-1.6	-1.1	-2.4	-1.2	-1.8	-0.7	-1.5	-1.6	-1.8	-1.6	-0.7	-1.6	-1.4	-1.7	-2.1	-0.4	-0.7	-1.5	-0.9	-1.7
Alzheimer’s Disease (in father)	1.7	1.8	3.8	1.1	1.2	1.7	1.7	1.2	0.1	1.3	1.2	1.2	1.8	1.2	0.8	1.2	-0.0	1.9	-1.3	1.1	1.2	1.6	2.0	1.1	1.6	1.6
Average weekly fortified wine intake	1.7	2.0	5.4	1.3	1.4	0.5	1.7	1.8	1.4	2.3	1.7	1.0	1.0	1.7	0.8	1.6	1.0	0.8	-0.1	1.4	1.4	1.9	1.5	1.7	1.6	1.2
Angina (self-reported)	1.7	2.3	4.5	-1.3	-1.5	-1.0	-1.3	-1.7	-0.7	-0.8	-1.4	-1.5	-1.6	-1.5	-1.4	-1.9	-1.3	-1.6	1.2	-1.7	-1.3	-2.1	-1.8	-1.3	-1.9	-1.7
Myopia	1.7	2.5	5.7	2.0	1.2	0.4	1.6	1.4	0.5	0.3	1.6	2.4	2.1	1.7	1.3	1.7	1.8	1.8	-0.9	1.7	1.4	1.9	1.5	1.8	1.8	1.8
Alzheimer’s Disease (in mother)	1.6	1.9	6.5	0.6	-0.1	0.4	1.5	1.6	1.9	2.5	1.7	1.1	1.3	1.6	1.8	0.4	-0.6	2.0	0.5	1.1	1.6	1.0	1.3	1.8	1.0	1.2
Hip circumference	1.6	6.8	12.0	2.8	2.4	2.9	2.9	3.1	1.1	3.2	2.7	3.5	3.0	2.8	2.5	2.6	2.2	2.6	-1.6	2.5	2.4	2.9	1.1	2.6	2.7	2.7
Pulse rate	1.6	2.8	9.4	2.1	2.0	0.8	1.7	1.5	1.4	1.5	1.5	1.6	1.8	1.4	1.3	2.0	3.1	0.4	-0.4	2.3	1.7	1.6	1.0	1.4	1.9	1.6
Medication: Paracetamol	1.6	2.7	5.0	-2.2	-1.6	-2.1	-1.8	-1.5	-1.5	-2.2	-1.8	-1.2	-1.5	-1.9	-1.4	-1.4	-1.0	-1.1	0.1	-1.8	-2.0	-1.3	-2.0	-1.9	-1.8	-1.4
Back pain experienced in last month	1.6	2.3	6.2	0.5	0.7	-1.5	1.7	1.9	2.3	1.4	2.1	2.5	1.6	1.9	0.4	0.6	0.8	1.4	1.1	1.4	1.6	1.6	1.4	1.9	1.0	0.8
Medication: Paracetamol	1.6	2.5	4.6	-2.2	-1.4	-1.8	-1.9	-1.6	-1.3	-2.0	-1.7	-1.7	-1.7	-1.9	-1.4	-1.3	-0.6	-1.4	0.5	-1.5	-1.7	-1.5	-1.8	-1.8	-1.8	-1.3
Crohns Disease (2017)	1.5	3.3	9.0	-1.5	-2.3	-0.3	-1.7	-2.0	-0.8	-1.4	-1.7	-2.7	-1.9	-1.9	-1.3	-2.1	-3.0	-0.9	1.6	-1.8	-1.0	-2.8	-1.1	-1.7	-2.1	-1.5
Time employed in main current job	1.5	1.7	3.8	-1.7	-1.9	-1.9	-1.3	-0.7	-0.1	-1.7	-0.8	-1.1	-1.4	-1.1	-1.6	-1.6	-0.9	-1.3	1.2	-1.2	-1.2	-0.9	-1.1	-1.0	-1.4	-1.6
Respiratory disease	1.4	3.1	6.8	-1.7	-1.6	-1.6	-2.1	-1.9	-1.3	-1.8	-1.7	-0.9	-2.1	-1.5	-1.4	-2.6	-1.2	-2.1	-0.0	-2.1	-2.2	-1.0	-2.1	-1.6	-1.7	-2.4
Ever used hormone-replacement therapy (HRT)	1.4	1.8	5.7	1.2	0.6	0.4	1.2	1.2	1.4	1.1	1.5	2.4	2.1	1.5	1.1	1.1	1.2	1.8	0.8	1.6	1.6	0.4	1.4	1.5	0.8	1.0
Angina	1.4	1.8	3.8	-1.2	-1.5	-1.1	-1.1	-1.4	-0.6	-0.6	-1.2	-1.2	-1.3	-1.3	-1.2	-1.8	-1.2	-1.4	1.3	-1.5	-1.1	-2.0	-1.7	-1.1	-1.8	-1.6
Alcohol intake versus 10 years previously	1.4	2.1	5.7	1.3	2.4	1.5	1.4	0.9	1.2	1.6	1.0	2.2	1.5	1.2	1.4	1.9	2.3	1.0	-1.0	1.5	0.9	1.4	0.7	1.0	1.3	1.2
Osteoporosis (self-reported)	1.4	1.7	5.6	1.8	1.8	2.4	1.3	1.0	0.1	0.7	0.9	0.7	1.4	1.1	1.3	0.9	1.3	0.7	-1.4	1.4	1.2	1.4	1.5	0.9	1.6	1.4
Number of operations (self-reported)	1.4	2.1	6.5	-1.1	-0.4	-0.1	-2.0	-1.4	-1.5	-0.3	-2.0	-1.5	-1.4	-1.9	-1.1	-0.5	1.5	-2.6	0.1	-1.3	-1.6	-1.7	-1.6	-1.8	-1.4	-1.4
Major Depression (MDD)	1.3	1.5	5.1	-1.4	-1.2	-2.3	-1.3	-1.2	0.1	-0.5	-0.8	-1.6	-1.4	-1.0	-1.4	-1.1	-1.2	-1.2	1.2	-1.1	-0.7	-1.5	-0.9	-1.0	-1.4	-1.2
Pulse wave reflection index	1.3	1.6	3.5	-1.2	-1.8	0.5	-1.3	-1.3	-1.7	-1.8	-1.1	-0.6	-1.0	-1.0	-1.2	-1.9	-1.8	-0.5	-0.3	-1.6	-1.3	-0.7	-0.9	-1.2	-1.0	-1.3
Medication: Lisinopril	1.3	1.7	3.8	1.0	0.9	-0.3	1.4	1.9	1.6	1.2	1.9	0.7	0.9	1.8	1.7	1.1	0.3	1.4	-0.1	1.4	1.5	1.1	0.7	1.9	1.0	1.4
Nervous feelings	1.2	2.3	4.0	1.8	0.4	1.7	1.8	2.0	1.1	1.6	1.5	1.8	2.0	1.5	2.0	1.2	0.6	1.6	0.3	1.5	1.6	1.3	1.8	1.5	1.6	1.2
Loud music exposure frequency	1.2	1.3	4.6	-1.5	-1.7	-1.0	-1.0	-0.9	-0.0	-1.3	-0.7	-0.2	-0.6	-1.0	-1.8	-0.8	0.0	-1.0	2.1	-0.6	-0.8	-1.3	-1.2	-1.0	-1.5	-1.2
Worry too long after embarrassment	1.2	2.0	3.9	-1.8	-1.7	-1.6	-0.9	-1.3	-0.6	-1.5	-1.2	-0.7	-1.4	-1.4	-1.4	-1.8	-1.1	-1.1	2.0	-1.4	-1.4	-1.4	-0.9	-1.3	-1.8	-2.0
Eye problems/disorders: None of the above	1.2	1.4	4.0	0.6	0.7	0.6	1.2	1.8	0.3	0.5	1.3	2.0	1.7	1.3	0.4	0.9	1.1	1.0	-0.2	1.1	1.1	1.5	1.8	1.3	1.3	0.9
Supplements: Vitamin C	1.2	1.4	2.9	-0.9	-0.5	-1.3	-1.6	-1.3	-1.3	-1.2	-1.7	-0.9	-1.1	-1.5	-1.0	-0.8	0.2	-1.6	-0.2	-1.3	-1.6	-1.0	-0.6	-1.5	-1.0	-1.4
Medication: Aspirin	1.2	1.5	3.9	-1.2	-1.2	-1.4	-1.0	-1.1	-0.2	-0.6	-1.0	-1.6	-2.0	-1.0	-0.9	-1.4	-1.9	-0.7	0.4	-1.3	-1.1	-1.6	-1.1	-0.9	-1.6	-1.1
Ever had prostate specific antigen (PSA) test	1.2	1.4	5.1	-1.0	-1.8	-0.1	-0.9	-1.4	-0.7	-0.9	-1.0	-1.0	-1.1	-1.2	-1.3	-0.9	-0.8	-0.9	1.0	-0.8	-0.9	-2.3	-1.4	-1.1	-1.8	-1.0
Pain experienced in last month	1.2	2.0	6.4	-0.9	0.4	1.0	-1.4	-1.8	-2.2	-2.2	-1.6	-2.5	-1.7	-1.4	-1.0	-0.1	-0.1	-1.5	-1.9	-1.1	-1.6	-0.4	-0.5	-1.8	-0.6	-0.5
Alzheimer’s Disease (including proxy)	1.1	1.6	5.4	0.7	0.0	1.3	1.5	0.9	0.8	2.1	1.5	1.2	1.8	1.3	1.3	0.9	-0.8	2.3	-0.0	1.1	1.2	0.7	1.6	1.3	0.8	1.5
Trunk fat percentage	1.1	4.4	11.2	1.6	1.7	0.5	2.2	2.5	1.5	1.7	2.5	3.3	2.9	2.5	1.7	2.3	2.8	2.0	-0.4	2.4	2.0	2.1	0.7	2.4	1.8	2.2
Taking other prescription medications	1.1	1.7	7.5	1.5	0.9	1.2	0.3	1.0	0.5	2.7	0.6	2.1	2.2	0.7	1.4	1.4	2.0	0.9	-0.3	1.1	1.0	0.6	0.7	0.8	1.2	1.1
Number of incorrect matches in round	1.1	1.8	4.3	1.4	-0.1	1.8	1.5	1.4	1.0	0.8	1.4	2.0	2.1	1.2	1.1	0.6	0.7	1.5	0.2	1.4	1.9	0.8	1.6	1.2	1.5	1.3
Body fat percentage	1.1	4.5	12.2	1.6	1.7	0.6	2.1	2.5	1.5	1.8	2.5	3.5	2.9	2.5	1.6	2.3	2.7	2.1	-0.4	2.4	2.0	2.1	0.6	2.4	1.8	2.1
Leg fat percentage (right)	1.1	4.1	12.0	1.3	1.6	0.8	1.9	2.5	1.4	1.8	2.4	3.5	2.9	2.3	1.4	2.4	2.7	2.1	-0.0	2.3	1.9	1.7	0.6	2.2	1.4	2.0
Pulse wave peak to peak time	1.1	1.3	3.1	1.4	1.7	0.8	1.3	1.1	1.1	1.2	0.9	-0.1	0.7	1.0	1.3	1.8	0.6	0.9	-0.9	1.1	1.0	1.2	1.3	1.1	1.3	1.5
Family relationship satisfaction	1.1	1.3	2.5	-0.5	-0.5	-1.2	-0.8	-1.6	-1.1	-1.3	-1.5	-1.3	-1.3	-1.5	-1.2	-0.7	-1.0	-0.7	-0.3	-1.1	-1.3	-1.4	0.8	-1.5	-1.2	-1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.2	4.4	1.3	0.9	0.3	1.8	1.6	1.6	1.3	1.8	2.1	2.1	1.6	1.7	1.5	1.4	1.9	0.7	1.9	1.9	0.4	0.6	1.7	0.9	1.6
Primary Biliary Cirrhosis	1.0	1.5	6.9	-0.5	-0.9	0.0	-1.0	-1.5	-1.0	-0.3	-1.4	-2.6	-1.5	-1.4	-0.6	-1.2	-1.5	-1.3	-0.5	-1.5	-0.9	-1.3	-0.8	-1.5	-0.8	-0.9
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	5.6	-0.7	-0.8	-1.2	-1.6	-1.0	0.3	-0.2	-1.0	-2.4	-1.4	-1.0	-0.5	-0.8	-0.4	-1.4	1.1	-0.5	-0.7	-0.9	-1.3	-0.9	-0.9	-0.2
Severe depression (siblings)	1.0	1.1	2.7	-1.6	-1.1	-0.8	-1.1	-1.0	-1.6	-0.4	-1.2	0.4	-0.6	-1.0	-1.0	-0.7	-0.3	-0.2	-0.4	-1.4	-1.6	-1.1	-1.2	-1.0	-1.4	-1.2
Relative age voice broke	1.0	1.6	4.7	0.8	0.6	0.2	1.8	1.2	1.9	0.9	1.4	-0.7	0.4	1.5	2.0	0.9	-0.2	1.2	0.1	1.3	1.5	0.8	2.2	1.4	0.9	1.5
Illnesses of mother	1.0	1.2	4.4	-1.7	-1.7	-1.0	-0.9	-1.2	-0.5	-2.1	-0.8	-0.1	-0.4	-1.0	-0.9	-0.9	-1.0	0.1	1.3	-0.5	-0.8	-1.3	-1.7	-1.1	-1.4	-0.6
Pulse wave Arterial Stiffness index	1.0	1.2	3.0	-1.4	-1.7	-0.7	-1.2	-1.0	-0.8	-1.2	-0.7	0.1	-0.7	-0.9	-1.1	-1.7	-0.6	-0.8	1.0	-1.0	-0.9	-1.2	-1.4	-1.0	-1.3	-1.4
Exposure to tobacco smoke at home	1.0	1.1	3.6	-0.5	-0.3	-0.8	-0.5	-1.0	-1.9	-1.7	-1.2	-0.9	-1.3	-1.0	-0.9	-0.5	-0.9	-0.7	-1.8	-1.2	-1.5	-0.1	-1.0	-1.0	-0.4	-0.7
Medication: Ventolin 100micrograms inhaler	1.0	1.3	3.5	-0.8	0.5	-1.2	-0.9	-1.3	-1.7	-0.5	-1.5	-0.4	-1.4	-1.3	-1.2	-0.6	0.7	-1.8	-1.2	-1.1	-1.9	0.2	-0.3	-1.4	-0.5	-1.2
Leg pain on walking	1.0	1.3	7.5	0.8	0.7	0.6	0.5	1.4	0.7	1.4	0.6	1.9	1.6	0.5	1.2	1.2	2.7	0.4	1.4	1.2	1.1	-0.1	0.6	0.8	0.3	0.8
Smoking status: Current	1.0	1.5	4.4	1.2	2.0	0.7	1.1	1.1	1.2	1.9	1.1	0.7	0.6	1.3	0.6	1.2	0.5	0.9	-1.2	1.0	0.7	2.1	1.5	1.2	1.6	1.2
Mother’s age at death	1.0	1.3	3.5	-0.4	-0.3	0.9	-0.7	-1.2	-1.9	-0.4	-1.8	-1.8	-1.1	-1.4	-0.6	-0.9	-0.6	-1.5	-1.3	-1.4	-1.4	-0.7	0.1	-1.5	-0.4	-1.1
Eye problems/disorders: Glaucoma	1.0	1.2	7.8	-0.4	-0.2	-1.1	-0.3	-1.6	-0.5	-0.7	-0.9	-1.1	-1.0	-0.9	-1.0	-0.9	-0.1	-1.7	-0.2	-1.1	-0.9	-0.7	-2.8	-1.0	-0.6	-1.3
Irritability	1.0	1.7	3.8	-1.2	-1.6	-1.0	-0.9	-1.5	0.0	-1.5	-0.9	-1.9	-1.7	-1.1	-1.4	-1.2	-1.9	-0.6	1.5	-1.0	-0.8	-1.8	-0.5	-0.9	-1.7	-0.9
Lupus	0.9	1.4	3.9	-0.5	-1.4	-0.8	-1.5	-1.4	-0.4	-0.8	-1.3	-1.3	-1.3	-1.4	-1.0	-0.9	-1.2	-0.8	0.9	-1.2	-1.0	-2.0	-0.8	-1.3	-1.5	-1.2
Blood White Count	0.9	6.5	11.6	-2.0	-1.3	-1.8	-2.5	-2.7	-3.4	-3.2	-3.0	-2.7	-2.8	-2.8	-3.2	-2.5	-1.4	-2.9	-1.9	-2.8	-3.3	-1.5	-1.3	-3.0	-2.0	-2.6
Medication for hormone replacement therapy	0.9	1.0	2.3	-1.2	-0.9	-0.9	-1.5	-1.0	-1.0	-0.5	-1.1	-0.8	-1.1	-1.1	-1.0	-0.4	-0.8	-0.5	0.5	-1.0	-1.4	-1.2	-0.4	-1.0	-1.4	-1.0
Breastfed as a baby	0.9	1.2	3.2	-0.6	-1.0	-0.5	-0.8	-1.1	-1.2	-1.8	-1.4	-1.2	-1.0	-1.4	-1.1	-1.2	-1.1	-1.0	-0.0	-1.2	-0.9	-1.2	0.3	-1.4	-0.8	-1.0
Blood clot in the leg (DVT)	0.9	1.1	2.6	0.9	0.5	-0.4	1.1	1.2	1.3	0.9	1.6	0.8	0.8	1.6	0.7	-0.0	-0.2	1.2	-0.3	1.2	1.3	1.3	1.3	1.5	1.1	0.7
Mean time to correctly identify matches	0.9	1.7	3.8	-1.8	-1.8	-1.5	-1.5	-0.9	-0.0	-1.2	-0.8	-1.6	-1.4	-1.0	-1.1	-0.8	0.5	-2.0	1.2	-0.7	-0.8	-1.8	-1.8	-1.1	-1.7	-1.1
Leg fat mass (right)	0.9	3.7	11.1	1.6	1.8	1.0	2.0	2.3	1.4	1.6	2.2	3.3	2.5	2.2	1.2	2.0	2.6	1.8	-0.4	2.0	1.7	1.8	0.4	2.1	1.5	1.7
Commuting to job workplace: Walk	0.9	0.9	5.4	-0.1	-0.9	-0.8	-1.2	-0.8	-0.5	-2.3	-0.5	-0.6	-0.8	-0.7	-0.6	-1.2	0.3	-1.3	0.3	-0.6	-0.4	-1.0	-1.9	-0.7	-0.6	-0.9
Breast cancer (self-reported)	0.9	1.0	4.4	-1.6	-1.3	-1.2	-1.4	-0.4	0.2	-0.1	-0.1	0.9	-0.4	-0.3	-1.3	-0.8	0.9	-0.9	1.5	-0.4	-0.7	-0.7	-2.1	-0.3	-1.3	-1.1
Osteoarthritis (self-reported)	0.9	1.2	2.9	-0.7	-0.1	-0.2	-1.3	-0.9	-0.9	-0.4	-1.4	-1.0	-1.3	-1.4	-1.2	-0.7	0.6	-1.7	0.0	-0.9	-1.4	-1.3	-1.5	-1.3	-1.2	-1.2
Leg fat percentage (left)	0.9	3.1	10.1	1.2	1.4	0.5	1.7	2.1	1.2	1.5	2.1	3.2	2.5	2.0	1.0	2.1	2.2	1.9	-0.3	2.0	1.6	1.6	0.5	1.9	1.3	1.8
Ever depressed for a whole week	0.9	1.1	4.1	-0.3	-0.5	-2.0	0.6	1.2	1.2	-0.5	1.2	1.6	1.1	0.9	-0.1	0.1	1.5	0.1	2.0	1.1	0.9	-0.4	-1.5	1.0	-0.3	0.4
Worry (Nagel 2018)	0.8	1.8	3.9	1.5	0.5	1.4	1.9	1.6	0.5	1.6	1.2	2.0	1.8	1.4	1.5	0.5	0.3	1.6	-0.3	1.1	1.3	1.4	1.4	1.4	1.5	0.8
Trunk fat mass	0.8	3.4	9.6	1.4	1.7	0.6	2.0	2.2	1.3	1.3	2.1	3.1	2.3	2.2	1.4	2.0	2.6	1.6	-0.5	2.0	1.6	2.0	0.3	2.0	1.5	1.8
Depression (self-reported)	0.8	1.0	2.0	0.8	0.8	-0.4	1.4	1.2	0.5	-0.3	1.2	1.4	1.1	1.2	1.0	0.1	0.3	1.2	-0.9	0.8	0.9	1.3	1.4	1.2	1.1	0.5
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	3.0	1.4	1.6	1.4	1.3	1.1	0.6	0.7	1.1	0.2	0.5	1.2	1.1	0.7	-0.2	0.6	-1.1	1.1	1.2	1.7	0.6	1.1	1.7	1.0
Whole body fat mass	0.8	3.4	10.2	1.4	1.7	0.6	2.0	2.2	1.4	1.4	2.1	3.2	2.4	2.2	1.2	1.9	2.6	1.6	-0.4	2.0	1.6	2.0	0.3	2.0	1.5	1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	1.0	2.7	-0.9	-1.3	0.2	-0.7	-0.9	-1.1	-0.6	-1.0	0.3	-0.0	-1.0	-1.3	-1.6	-1.1	-0.6	0.3	-1.4	-0.8	-1.1	-1.3	-1.0	-1.1	-1.2
Ever had bowel cancer screening	0.8	1.0	2.3	1.2	1.4	0.1	1.2	1.1	1.1	1.5	1.0	-0.0	0.7	1.0	0.5	1.4	1.2	0.5	-0.4	1.3	1.0	0.6	0.7	1.0	0.9	1.2
Medication for cholesterol	0.8	1.2	2.6	0.8	0.5	1.1	1.6	1.5	0.9	1.2	1.3	0.6	1.1	1.4	1.4	0.7	0.4	1.1	-0.8	1.0	1.2	1.4	0.4	1.4	1.3	1.2
Risk taking	0.8	1.2	2.8	-1.4	-1.2	-0.2	-1.0	-0.6	-0.2	-1.7	-0.8	-1.3	-1.5	-0.9	-1.4	-0.9	-0.8	-0.6	1.4	-0.7	-1.1	-1.2	-0.4	-1.0	-1.6	-0.8
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	2.5	0.8	0.5	-0.6	1.2	1.1	1.1	0.8	1.6	0.9	0.7	1.6	0.4	-0.2	-0.2	1.1	-0.6	1.0	1.1	1.5	1.3	1.4	1.1	0.6
Schizophrenia vs Biploar Disorder	0.7	0.9	3.1	1.5	0.4	0.8	1.2	0.9	0.8	0.4	1.0	0.7	1.3	0.8	1.8	0.5	0.4	1.0	0.6	0.9	1.4	0.5	0.3	0.8	1.1	0.8
Irritable Bowel Disease (IBD)	0.7	1.6	4.3	-1.3	-1.6	-0.7	-1.2	-1.3	0.2	-0.1	-0.9	-1.9	-1.3	-1.2	-0.7	-1.4	-1.9	-0.6	1.6	-1.3	-0.5	-2.1	-0.7	-1.1	-1.6	-1.3
Waist Hip Ratio (WHR)	0.7	3.0	15.5	-1.3	-1.4	-3.9	-1.0	-2.0	-0.2	-2.6	-1.5	-0.7	-1.2	-1.5	-0.9	-2.7	-0.9	-1.4	1.1	-1.6	-1.3	-2.0	0.1	-1.3	-1.7	-2.5
Number of treatments/medications taken	0.7	1.2	7.5	0.9	1.2	0.0	0.3	1.1	1.1	2.7	1.0	1.5	1.5	1.0	1.0	1.0	1.3	0.6	-0.5	0.9	0.8	0.8	0.9	1.0	0.9	0.7
Relative age of first facial hair	0.7	1.5	4.1	1.1	-0.2	1.8	1.5	1.0	2.0	1.3	1.3	-1.5	0.0	1.2	1.6	0.4	-1.3	1.0	0.9	1.2	1.8	-0.1	1.3	1.1	0.7	1.1
Current tobacco smoking	0.7	1.2	4.9	1.0	2.2	0.6	0.9	0.9	0.7	1.7	0.7	0.2	0.3	0.9	0.2	1.1	0.7	0.4	-1.6	0.7	0.3	2.1	1.4	0.9	1.5	0.9
Qualifications: None of the above	0.7	1.6	5.5	-1.4	-0.8	-2.3	-1.5	-1.4	-0.4	0.3	-1.2	-0.4	-0.6	-1.4	-1.5	-0.7	1.2	-1.5	1.2	-0.9	-1.2	-1.4	-1.4	-1.4	-1.5	-1.2
Shortness of breath walking on level ground	0.7	0.8	3.1	-0.3	-1.1	-0.5	-1.0	-0.6	-0.3	0.3	-0.8	-0.6	-0.6	-1.0	-1.0	-1.2	-0.6	-0.7	1.3	-0.8	-0.5	-1.8	-1.1	-0.9	-1.1	-1.0
Average weekly champagne plus white wine intake	0.7	0.9	2.2	0.0	-0.1	1.1	0.1	0.9	0.4	0.4	0.8	1.4	1.3	0.7	1.3	1.3	1.1	1.3	1.5	1.1	0.8	0.1	1.2	0.8	0.0	1.0
Wears glasses or contact lenses	0.7	0.8	3.3	0.2	-0.5	-0.1	1.1	0.9	0.9	-0.4	0.9	1.8	1.0	0.9	0.8	0.7	0.0	1.6	0.8	0.9	0.7	0.7	-0.2	1.0	0.4	0.9
Hearing aid user	0.7	0.8	3.6	-0.5	-1.3	-0.9	-1.2	-0.5	-0.2	-1.3	-0.8	-0.2	-0.5	-1.0	-0.5	-0.5	-0.4	-0.6	1.1	-0.5	-0.6	-1.3	-1.9	-0.8	-0.9	-0.5
Medication: Atorvastatin	0.7	0.9	5.5	-1.0	-1.7	-1.5	-1.0	-0.5	1.0	-0.5	-0.2	-0.3	-0.2	-0.4	-0.0	-0.9	-1.1	0.1	2.3	-0.7	-0.1	-1.3	-0.8	-0.0	-1.3	-0.4
Average weekly beer plus cider intake	0.7	1.0	2.7	0.5	0.8	-1.0	1.0	0.7	1.6	0.9	1.2	1.0	0.8	1.0	1.2	1.1	1.1	1.1	1.1	1.3	1.1	0.6	0.7	1.0	0.5	1.1
Leg fat mass (left)	0.7	2.9	9.6	1.3	1.7	0.8	1.8	2.0	1.2	1.4	2.0	3.1	2.2	2.0	0.9	1.7	2.3	1.6	-0.5	1.8	1.4	1.8	0.2	1.9	1.4	1.5
Alcohol usually taken with meals	0.6	0.9	2.3	-0.9	-1.2	0.1	-1.3	-0.7	-1.3	-0.8	-1.2	-0.8	-1.0	-1.2	-0.9	-0.4	-0.7	-0.6	0.5	-1.1	-1.0	-1.5	-0.3	-1.0	-1.3	-0.9
Financial difficulties in last 2 years	0.6	0.8	3.0	-0.7	0.1	-1.7	-0.5	-0.7	-0.9	-1.6	-0.7	0.1	-0.7	-0.6	-1.2	-0.9	0.1	-0.8	-0.5	-0.9	-1.2	0.6	-1.5	-0.8	-0.2	-1.2
Hair/balding pattern: Pattern 3	0.6	0.9	2.5	0.6	1.4	0.2	0.4	0.9	1.3	0.5	0.8	0.2	0.8	0.8	0.7	1.6	1.4	0.8	0.6	1.3	0.9	1.0	0.5	0.9	0.8	1.6
Asthma	0.6	1.1	3.0	-0.9	-0.9	-0.4	-1.3	-1.1	-1.2	-0.3	-1.0	0.6	-0.8	-0.7	-0.7	-1.7	-0.8	-1.0	-0.7	-1.5	-1.5	0.1	-1.7	-0.7	-0.6	-1.5
Prospective memory result	0.6	0.7	4.0	0.3	-0.4	0.0	0.4	0.9	1.1	1.0	1.1	2.0	1.4	0.9	0.1	-0.0	0.3	1.2	1.2	0.4	0.9	0.4	0.6	1.1	0.2	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	4.3	-0.8	-1.9	-1.2	-0.6	-0.5	0.3	-0.8	-0.3	-0.5	-0.8	-0.5	-1.1	-1.5	-2.1	0.1	1.4	-0.7	-0.4	-1.0	-0.3	-0.6	-1.0	-1.0
Hair/balding pattern: Pattern 4	0.6	1.5	7.2	1.3	1.3	0.6	1.3	0.5	-0.5	1.5	0.8	1.4	1.8	0.9	0.8	0.4	0.1	1.2	-2.7	0.6	1.0	1.3	1.5	0.8	1.6	0.8
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	4.4	1.8	1.6	2.1	0.6	0.6	1.0	1.3	0.9	-0.2	0.8	0.9	0.6	1.5	1.0	0.1	-0.6	1.2	1.1	1.0	0.8	0.8	1.4	1.2
Birth weight	0.6	1.2	4.7	-0.4	-0.1	0.0	-0.3	-1.3	-1.4	-1.2	-1.1	-1.9	-1.5	-0.9	-0.4	-1.1	-1.9	-0.7	-2.2	-1.2	-1.1	0.2	-0.4	-1.0	-0.0	-0.5
Chronic bronchitis/emphysema (mother)	0.6	0.7	4.1	0.7	1.7	0.1	0.6	0.8	0.9	1.0	0.7	0.9	0.7	0.6	-0.5	0.8	2.0	-0.2	-0.2	0.6	0.5	0.3	0.5	0.8	0.5	0.3
Comparative body size at age 10	0.6	1.6	4.3	-0.3	-0.5	-0.5	-0.8	-1.6	-1.3	-0.8	-1.5	-1.3	-1.4	-1.4	-1.3	-1.4	-0.4	-1.8	-0.6	-1.5	-1.2	-1.0	-2.1	-1.5	-0.7	-1.5
Mouth/teeth dental problems: Loose teeth	0.6	0.7	2.8	-0.9	-1.7	-0.9	-0.5	-1.0	-0.2	-0.3	-1.0	-0.4	-0.4	-1.0	-0.4	-0.6	-0.9	-0.2	1.0	-0.7	-0.7	-1.5	-0.6	-0.8	-1.2	-0.5
Medication: Aspirin	0.6	0.9	1.9	-1.0	-0.9	-1.1	-0.7	-0.8	0.1	-0.5	-0.7	-1.0	-1.4	-0.7	-0.6	-1.0	-1.4	-0.4	0.6	-1.0	-0.8	-1.4	-1.1	-0.6	-1.3	-0.8
Average weekly red wine intake	0.6	0.9	1.7	0.7	0.9	1.3	1.3	0.9	0.5	0.5	1.0	1.1	0.9	1.2	1.3	0.7	-0.0	1.2	-0.8	0.6	0.7	1.1	1.0	1.1	0.9	0.6
Asthma (self-reported)	0.6	1.3	3.0	-0.9	-0.8	-0.9	-1.3	-1.2	-1.3	-0.5	-1.1	0.7	-0.9	-0.8	-0.9	-1.7	-0.7	-1.2	-0.8	-1.6	-1.7	0.3	-1.6	-0.8	-0.6	-1.6
Commuting to job workplace: Cycle	0.6	0.7	2.8	-1.0	-1.0	-1.4	-0.2	0.6	1.6	0.1	0.8	1.2	0.5	0.7	-0.2	-0.4	-1.0	1.3	1.7	0.1	0.1	0.2	0.7	0.9	-0.7	-0.0
Bipolar Disorder or Schizophrenia	0.5	1.2	2.9	-1.6	-0.9	-1.5	-1.1	-1.1	-0.3	-1.1	-1.1	-1.4	-1.5	-1.1	-1.7	-0.7	-0.6	-0.7	0.9	-0.9	-1.2	-1.0	0.3	-1.0	-1.4	-0.8
Reaction Time	0.5	1.0	3.5	-1.5	-0.7	-1.9	-0.9	-0.3	-0.1	-0.9	-0.3	-0.9	-1.2	-0.4	-1.0	-0.8	0.4	-1.7	0.5	-0.8	-0.8	-0.4	-1.5	-0.6	-1.0	-1.2
Ovarian Cancer	0.5	0.7	3.8	-0.6	-0.2	-0.8	-0.6	-0.6	-1.9	-0.2	-1.0	-0.3	-0.6	-0.8	-0.6	-0.8	-1.1	-0.1	-1.1	-1.2	-1.1	0.0	0.7	-0.9	-0.3	-0.6
Crohns Disease (2012)	0.5	0.8	2.6	-0.2	-0.6	0.2	-0.6	-0.9	-1.0	-1.1	-0.9	-1.5	-0.7	-1.0	-0.6	-1.4	-1.6	-0.2	0.2	-1.1	-0.2	-1.5	-0.6	-0.9	-0.8	-0.8
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.5	-0.9	-0.5	-0.1	-0.5	-0.3	-0.1	-0.6	-0.6	0.7	-0.4	-0.9	-0.5	-1.1	0.7	-0.8	0.8	-0.6	-0.3	-1.2	-1.6	-0.5	-0.9	-1.1
Medication: Metformin	0.5	0.7	3.5	1.0	1.9	0.6	-0.6	-0.5	0.7	1.2	-0.5	-1.5	-0.6	-0.4	-0.2	0.6	1.0	-1.6	-0.5	-0.0	-0.0	-0.3	0.1	-0.5	0.3	-0.1
Age when periods started (menarche)	0.5	1.1	2.0	-1.2	-0.7	-1.3	-1.3	-1.2	-0.9	-0.9	-1.3	-1.1	-1.1	-1.3	-0.8	-0.7	-0.5	-0.8	-0.1	-1.3	-1.4	-1.0	0.2	-1.2	-1.2	-1.2
Diverticular disease/diverticulitis (self-reported)	0.5	0.6	1.8	-0.2	-0.2	-1.4	-0.8	-0.5	-1.3	-0.1	-1.1	-0.1	-0.5	-1.1	-0.2	-0.7	0.1	-1.1	-0.9	-0.8	-0.8	-0.7	-1.0	-1.0	-0.3	-0.8
Body mass index (BMI)	0.5	2.1	7.8	1.3	1.3	0.4	1.7	1.6	1.1	1.1	1.8	2.8	1.9	1.8	0.8	1.0	1.6	1.5	-0.5	1.4	1.2	1.8	0.3	1.6	1.3	1.1
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.6	-0.5	0.0	-0.7	-0.1	-1.0	-0.6	0.2	-0.7	-1.2	-0.7	-0.7	-0.6	-1.1	-0.7	-1.0	-0.1	-0.8	-0.5	-1.0	-0.7	-0.8	-0.6	-1.1
Arm fat mass (right)	0.5	2.0	7.5	1.0	1.2	0.3	1.6	1.7	1.1	1.1	1.8	2.7	1.8	1.8	0.9	1.1	1.7	1.4	-0.5	1.4	1.2	1.7	0.2	1.7	1.1	1.1
Tense / ‘highly strung’	0.5	0.9	1.8	0.7	-0.1	1.2	1.1	0.9	1.2	0.8	1.2	0.9	0.8	1.0	0.4	1.0	0.7	1.3	1.3	1.3	0.9	0.1	0.9	1.0	0.1	0.8
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.5	-1.2	-0.1	-1.1	-0.9	-1.0	-0.5	-0.4	-1.0	-0.7	-1.0	-1.0	-0.5	-0.1	0.5	-1.0	0.6	-0.7	-1.1	-0.5	-0.9	-1.0	-0.9	-0.5
Medication for cholesterol, blood pressure or diabetes	0.5	0.8	3.3	0.4	-0.4	0.2	-0.4	-0.9	-1.8	-1.0	-1.2	-0.6	-0.9	-1.2	-1.3	-0.8	-0.1	-1.5	-0.6	-0.8	-0.8	-0.2	-1.0	-1.4	-0.0	-0.9
Qualifications: College or University degree	0.5	1.7	4.9	-0.8	-1.3	0.7	-0.8	-1.4	-1.9	-1.0	-1.5	-1.9	-1.6	-1.5	-1.0	-0.9	-2.2	-0.6	0.3	-1.6	-1.2	-1.4	-0.4	-1.3	-1.2	-1.0
Medication: Blood pressure	0.5	1.0	3.3	-0.0	0.3	-0.6	0.9	0.9	1.8	0.6	1.3	0.8	0.9	1.3	1.5	0.7	-0.2	1.8	-0.0	0.8	0.9	0.3	0.9	1.5	0.2	1.0
Heart disease (mother)	0.5	0.6	1.2	0.8	0.4	0.9	0.4	0.9	-0.3	1.0	0.4	0.6	1.1	0.5	1.1	0.7	-0.1	1.1	-0.7	0.2	0.7	0.4	1.1	0.6	0.9	0.9
Arm fat percentage (left)	0.5	2.2	7.8	1.1	1.0	-0.1	1.5	1.7	1.2	1.1	1.9	2.8	2.1	1.9	0.9	1.3	1.7	1.6	-0.2	1.5	1.4	1.4	0.3	1.8	1.1	1.2
Eye problems/disorders: Cataract	0.5	0.6	1.1	0.1	-0.1	0.7	-0.6	-1.0	-0.9	-0.2	-1.0	-0.8	-0.7	-1.0	-0.7	-0.9	-0.3	-1.0	-0.8	-0.8	-0.6	-0.9	-0.4	-1.0	-0.4	-0.9
Arm fat mass (left)	0.5	2.0	8.0	0.9	1.2	0.0	1.7	1.7	1.2	1.0	1.8	2.8	1.8	1.8	0.8	1.0	1.8	1.3	-0.3	1.4	1.1	1.6	0.0	1.7	1.1	1.0
Unable to work because of sickness or disability	0.5	0.6	2.8	0.5	0.1	-0.5	0.8	0.8	1.7	1.0	1.0	1.2	0.9	0.9	0.6	0.4	0.7	0.6	1.1	0.7	0.8	0.3	0.4	0.9	0.2	0.5
Diabetes (mother)	0.4	0.5	3.1	-0.6	0.0	-0.8	0.7	0.7	1.8	1.2	0.8	0.6	0.5	0.8	0.2	0.4	-0.1	0.6	1.0	0.4	0.4	0.7	0.2	0.8	0.0	0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	3.7	-0.8	-0.6	-1.9	0.2	0.2	1.0	0.5	0.5	-0.2	-0.6	0.4	-0.7	-0.9	-1.1	0.3	0.7	-0.3	-0.2	-0.1	0.2	0.5	-0.8	-0.5
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.5	0.9	0.9	0.5	0.5	0.7	0.1	0.8	0.5	0.7	0.4	0.7	1.2	0.4	0.5	0.3	-1.2	0.3	0.4	0.5	0.4	0.8	0.8	0.2
Stomach or abdominal pain in last month	0.4	0.5	2.4	0.2	0.3	-0.7	0.9	0.5	1.5	1.5	0.7	0.8	0.3	0.6	0.2	-0.1	0.1	0.4	1.2	0.5	0.7	0.5	-0.6	0.7	0.3	0.0
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	3.6	-0.4	-0.8	-0.0	0.7	0.8	1.2	1.0	0.9	1.0	0.2	0.6	-0.7	-0.2	-0.5	0.8	1.9	0.2	0.4	-0.1	0.1	0.8	-0.6	-0.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	3.7	0.2	0.3	-1.9	0.7	0.9	0.7	-1.3	0.6	0.5	0.4	0.6	0.2	0.2	0.3	0.7	0.6	0.9	0.6	0.3	0.4	0.6	0.3	0.7
Medication: Ramipril	0.4	0.5	3.8	-0.0	1.0	-1.4	-0.1	0.4	0.1	0.3	0.2	0.5	0.4	0.3	0.8	0.7	0.9	0.7	-0.6	0.0	-0.1	0.3	1.9	0.5	0.2	0.3
Arm fat percentage (right)	0.4	1.8	6.6	1.0	0.7	0.1	1.3	1.5	1.0	1.2	1.7	2.6	2.0	1.7	0.9	1.1	1.4	1.6	-0.4	1.3	1.2	1.3	0.3	1.6	1.0	1.2
Mouth/teeth dental problems: Dentures	0.4	0.7	3.4	-0.2	-1.4	-0.4	-0.5	-1.1	0.1	0.3	-0.7	-0.7	-0.6	-0.7	-0.5	-1.0	-0.5	-0.9	0.4	-0.8	-0.5	-1.3	-1.8	-0.8	-0.8	-1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.3	3.3	1.2	1.0	0.6	1.8	1.5	1.1	0.8	1.7	1.5	0.8	1.5	1.3	0.6	0.5	1.1	-0.4	1.1	1.2	1.2	0.7	1.5	1.0	0.5
Length of working week for main job	0.4	0.4	1.0	0.4	-0.1	-0.3	1.0	0.9	0.8	0.8	0.9	-0.8	0.2	0.9	0.8	0.2	-0.8	0.6	-0.0	0.5	0.8	0.3	-0.0	0.7	0.3	0.5
Number of full brothers	0.4	0.4	1.4	0.5	1.0	-0.4	0.2	0.7	0.7	1.2	0.9	0.4	0.3	0.9	-0.0	0.4	0.1	0.5	-0.9	0.4	0.6	1.0	0.0	0.9	0.8	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	2.2	0.6	1.1	0.3	0.2	-0.1	-1.0	-1.0	-0.6	0.5	0.1	-0.4	0.4	0.8	1.5	-0.8	-1.1	0.0	-0.5	0.2	-0.5	-0.2	0.4	0.2
Medication for pain relief, constipation, heartburn	0.4	0.7	3.6	1.4	0.9	1.9	0.5	0.3	0.0	0.1	0.5	-0.2	0.4	0.6	1.2	0.5	0.6	-0.1	-0.7	0.8	1.0	0.4	1.2	0.5	1.0	0.6
Medication: Allopurinol	0.4	0.5	1.9	-0.6	-0.1	-0.8	-0.7	-0.8	-0.9	-1.2	-0.6	-0.6	-0.5	-0.7	-0.8	-0.3	1.0	-1.4	-0.1	-0.3	-0.7	-0.2	-0.4	-0.7	-0.4	-0.5
Medication: Seretide 50 evohaler	0.4	0.5	1.1	0.2	0.2	-0.1	1.0	0.8	0.2	0.7	0.8	0.4	1.1	0.9	0.6	0.4	-0.1	1.0	-0.3	0.5	0.7	0.8	0.7	0.9	0.7	1.0
Number of full sisters	0.4	0.5	1.7	0.4	0.5	-0.2	0.9	0.9	1.1	1.0	1.0	0.4	0.1	1.1	1.3	-0.4	0.1	0.4	-0.1	0.3	0.7	1.0	0.2	1.2	0.6	0.1
Overall health rating	0.4	0.8	4.8	-0.8	-0.9	-2.2	-1.0	-0.2	0.3	1.1	-0.2	1.4	-0.0	-0.2	-1.3	-1.0	0.7	-0.6	1.0	-0.4	-0.7	-0.3	-1.2	-0.2	-0.8	-1.2
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	2.7	0.8	-0.0	1.6	0.2	0.3	0.1	0.2	-0.2	-0.8	0.1	-0.1	1.4	1.2	0.2	0.2	0.1	0.7	0.8	-0.6	0.4	0.0	0.4	1.2
Smoking status: Previous	0.4	0.6	1.6	-0.3	-0.0	-0.7	-0.8	-1.0	-0.7	-0.4	-0.8	-1.2	-1.1	-0.8	-0.3	-0.6	0.2	-1.2	-0.5	-0.8	-0.9	-0.7	-0.0	-0.8	-0.6	-0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	2.3	-0.1	-0.2	1.5	-0.5	-0.5	-1.0	-0.2	-0.8	-0.1	-0.2	-0.7	0.9	-0.4	-0.4	0.0	-0.8	-0.6	-0.4	-0.6	-1.1	-0.8	-0.2	-0.4
Qualifications: nursing, teaching	0.4	0.6	3.1	-0.3	-0.9	1.7	-0.4	0.0	0.2	-0.7	-0.2	-0.8	-0.2	-0.3	1.1	0.1	-0.8	0.3	1.8	0.2	0.3	-1.5	0.1	-0.1	-0.8	0.2
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	2.2	-0.6	-0.3	-1.1	0.3	1.2	1.3	1.1	0.9	0.8	0.8	0.9	0.3	0.7	0.7	0.5	1.5	0.7	0.5	0.5	0.1	0.9	-0.0	0.4
Financial situation satisfaction	0.4	0.5	1.6	0.3	0.4	-1.0	0.9	0.6	1.0	-0.0	0.9	0.6	0.6	0.7	-0.5	0.7	0.4	1.1	1.3	1.2	0.8	0.5	0.0	0.6	0.2	0.8
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.8	-0.2	-0.9	-0.9	-0.8	-0.5	-0.6	-0.1	-0.6	0.7	-0.1	-0.7	-0.6	-0.7	0.4	-0.8	0.9	-0.4	-0.5	-1.0	-1.3	-0.6	-0.8	-0.8
High cholesterol (Self-reported)	0.4	0.7	2.2	-0.9	-0.4	-0.5	-1.4	-1.1	0.2	0.3	-0.9	-1.2	-0.8	-1.0	0.2	-0.2	-0.1	-1.0	0.9	-0.5	-0.5	-1.5	-0.3	-1.0	-1.1	-0.7
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	2.9	-0.7	-1.2	-0.4	-0.4	-0.5	0.2	0.4	-0.4	0.1	0.0	-0.5	0.3	-1.1	-0.7	-0.1	1.7	-0.6	-0.1	-1.1	-1.2	-0.4	-0.9	-0.7
Basal cell carcinoma (self-reported)	0.4	0.5	2.3	-0.3	0.2	-0.6	0.8	0.5	-0.2	0.0	0.8	0.9	0.1	0.9	-0.0	0.2	-1.0	1.3	-0.8	0.2	0.2	1.5	0.6	0.8	0.6	0.6
Depressed Affect (Nagel 2018)	0.3	0.6	2.1	0.2	0.2	0.2	0.8	1.1	1.0	1.4	1.1	0.3	0.8	1.0	0.8	0.7	0.1	1.2	0.1	0.8	0.7	0.4	0.5	1.1	0.2	0.9
Age at First Birth	0.3	0.4	3.2	-0.2	-0.4	-0.1	-0.2	-0.0	-0.1	-0.1	-0.1	-1.7	-0.8	-0.3	0.0	-0.6	-1.8	-0.3	0.1	-0.7	-0.1	-0.1	0.3	-0.3	-0.1	-0.4
Coronary Artery Disease (CAD)	0.3	0.4	1.9	0.7	0.3	0.9	-0.1	0.2	-1.4	0.5	-0.3	0.4	0.9	-0.1	-0.3	0.5	0.4	0.5	-1.3	-0.3	0.1	-0.0	0.8	-0.0	0.6	0.4
HDL Cholesterol	0.3	0.5	1.7	-0.7	-0.8	-0.3	-0.9	-0.5	-1.3	-1.0	-0.9	-0.2	-0.2	-0.9	-0.1	-0.3	-0.1	-0.5	-0.2	-0.7	-0.7	-0.8	-1.1	-0.9	-0.7	-0.4
Schizophrenia (2014)	0.3	0.7	2.5	-1.2	-0.7	-1.6	-0.6	-0.6	0.4	-1.3	-0.5	-0.9	-0.9	-0.6	-1.0	-0.1	-0.1	-0.0	1.4	-0.3	-0.6	-1.0	0.1	-0.5	-1.3	-0.3
Triglycerides	0.3	0.6	1.6	-1.0	-0.9	-1.0	-0.7	-0.7	-0.3	-0.3	-0.5	0.4	-0.5	-0.5	-0.8	-1.3	-1.2	0.2	0.9	-0.8	-0.5	-0.8	-0.4	-0.4	-0.8	-1.0
Blood Eosinophil Count	0.3	2.3	8.1	1.9	2.2	0.4	1.8	1.4	0.4	1.4	1.0	0.6	1.2	1.3	1.3	1.6	1.4	0.9	-2.1	1.4	1.2	1.6	2.8	1.2	1.9	1.6
Smoking Status	0.3	0.7	3.0	0.5	1.7	-0.3	0.5	0.5	1.2	1.5	0.6	-0.1	-0.3	0.7	0.3	1.2	1.2	-0.3	-0.4	0.7	0.2	1.1	1.1	0.7	0.6	0.5
Chronotype (morning person)	0.3	0.6	3.7	0.3	-0.3	1.2	-0.5	-0.2	-1.9	-1.3	-1.0	-0.3	-0.1	-0.8	-0.1	-0.4	-0.4	-0.3	-1.4	-0.8	-0.6	-0.4	-0.3	-0.8	-0.0	-0.3
Hearing difficulty/problems: Yes	0.3	0.5	2.6	-0.9	-1.2	-0.6	-0.6	-0.3	0.3	-0.3	-0.0	0.6	0.2	-0.2	-0.3	-1.0	-0.1	-0.2	1.0	-0.4	-0.2	-1.0	-1.6	-0.3	-1.0	-0.9
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	1.7	0.3	-0.2	-0.2	-0.3	0.3	0.5	1.1	0.1	1.3	1.1	0.2	1.0	0.3	-0.3	1.1	0.4	0.1	0.3	-0.3	0.0	0.3	0.1	0.2
Ever had hysterectomy (womb removed)	0.3	0.3	1.5	0.6	-0.0	0.6	-0.9	-0.3	-0.9	-0.0	-0.6	-1.0	-0.4	-0.5	0.5	-0.3	-0.6	-0.0	-0.5	-0.4	0.0	-0.9	-1.2	-0.4	-0.0	0.1
Pack years adult smoking proportion	0.3	0.5	3.1	0.1	-0.1	-0.0	-0.6	0.6	0.2	1.2	0.5	0.9	1.2	0.5	0.6	0.4	-0.9	1.8	0.3	0.4	0.5	0.1	0.6	0.6	0.1	0.8
Townsend deprivation index at recruitment	0.3	0.4	2.2	-0.4	-0.2	-1.5	-0.6	-0.5	-0.5	-0.7	-0.4	-0.5	-0.6	-0.4	-0.9	-0.8	-0.5	-0.3	-1.0	-0.6	-0.8	-0.1	0.2	-0.4	-0.4	-0.5
Serious illness, injury or assault to yourself	0.3	0.4	2.4	-0.1	-0.7	-1.1	-0.1	0.3	-0.1	0.0	0.4	1.6	0.8	0.4	0.2	-1.0	-0.8	1.3	0.2	-0.2	0.1	0.0	0.3	0.5	-0.2	-0.4
Supplements: Glucosamine	0.3	0.4	3.5	0.8	1.0	0.1	0.2	0.5	-0.5	0.5	0.1	0.6	0.3	0.3	0.0	0.3	0.8	-0.6	-1.9	0.0	-0.2	1.1	-0.1	0.2	0.9	0.1
Medication: Atenolol	0.3	0.4	3.3	0.0	0.5	-0.2	-0.1	-0.3	-1.1	0.4	-0.7	-0.8	-0.3	-0.5	-0.2	-0.1	-0.2	-0.5	-1.8	-0.7	-0.7	0.2	0.2	-0.7	0.2	-0.3
High blood pressure (mother)	0.3	0.5	1.7	0.9	1.1	0.6	0.9	1.0	0.5	0.9	0.7	-0.4	-0.4	0.7	0.3	-0.0	0.2	-0.4	-0.4	0.3	0.4	1.0	1.3	0.7	0.8	-0.1
Waist circumference	0.3	1.1	3.9	1.4	0.9	0.2	1.4	1.2	0.5	0.9	1.0	2.0	1.4	1.1	0.8	0.5	1.0	1.1	-0.7	0.9	0.8	0.9	0.7	1.0	1.0	0.7
Had menopause	0.3	0.3	1.3	0.9	0.0	1.0	-0.4	-0.0	0.3	0.9	-0.2	-0.3	0.4	-0.3	-0.7	0.5	1.2	-0.7	0.4	0.4	0.6	-0.8	-0.2	-0.1	0.2	0.4
Had other major operations	0.3	0.4	1.6	-0.1	-0.2	-0.2	-0.0	0.5	1.2	1.3	0.6	0.9	0.9	0.5	0.1	0.5	0.8	0.2	1.1	0.3	0.7	-0.3	-0.3	0.6	-0.1	0.2
Mouth/teeth dental problems	0.3	0.5	2.0	1.0	0.9	1.4	0.2	0.5	-0.9	-0.6	0.2	-0.1	0.4	0.2	0.4	0.3	-0.1	0.6	-1.2	0.4	0.5	0.4	1.4	0.3	0.8	0.7
Heart attack	0.3	0.4	2.8	0.2	1.2	-0.4	0.6	0.2	-0.5	0.3	-0.2	-0.2	-0.1	-0.1	0.4	-0.1	-0.3	0.0	-1.3	-0.5	-0.2	0.6	1.7	0.0	0.5	-0.2
Allergy	0.3	0.7	2.2	-1.2	-0.5	-1.0	-0.4	-0.7	0.1	-1.1	-0.4	-1.5	-1.0	-0.7	-1.1	-0.3	-0.1	-0.8	1.1	-0.4	-0.5	-1.1	-0.2	-0.7	-1.2	-0.6
Pain all over the body in last month	0.3	0.3	1.2	0.5	-0.7	0.0	-1.0	-0.7	0.5	0.8	-0.3	-0.9	-0.5	-0.4	0.3	-0.4	-1.1	-0.2	0.6	-0.3	0.0	-0.8	0.1	-0.4	-0.3	-0.3
Illnesses of siblings	0.3	0.4	2.6	0.1	-0.2	1.6	-0.6	-0.2	-0.5	-0.2	-0.6	0.3	0.2	-0.5	0.1	0.6	1.0	-0.4	0.4	0.1	-0.3	-0.2	-1.5	-0.5	-0.1	0.3
Weight	0.3	1.5	6.6	1.0	1.3	0.4	1.7	1.5	0.8	0.8	1.4	2.6	1.4	1.5	0.8	0.8	1.5	1.0	-0.6	1.1	0.8	1.7	-0.1	1.3	1.1	0.8
Father’s age at death	0.3	0.4	1.9	0.4	0.2	0.2	0.6	0.6	-0.1	0.6	0.3	-0.0	0.5	0.3	1.0	1.4	1.1	-0.1	0.7	0.8	0.7	0.3	0.1	0.3	0.5	1.1
Worrier / anxious feelings	0.3	0.5	2.7	0.4	-0.4	0.9	0.9	0.6	0.3	1.3	0.4	1.7	1.2	0.4	0.7	0.2	0.7	0.6	1.1	0.5	0.5	0.3	0.7	0.4	0.3	-0.1
Noisy workplace	0.3	0.4	2.0	-0.4	-0.9	-1.2	0.3	0.7	0.6	-0.1	0.6	0.9	0.7	0.4	0.3	-0.2	-0.4	1.1	1.4	0.3	0.4	-0.3	0.4	0.4	-0.3	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.3	1.4	-0.5	-0.2	-0.8	0.2	0.6	0.4	-0.2	0.8	1.2	0.8	0.6	-1.1	0.4	0.0	0.9	0.6	0.4	0.0	0.4	-0.2	0.5	-0.3	0.3
Ever highly irritable/argumentative for 2 days	0.3	0.4	2.3	0.5	-0.4	-0.8	0.7	0.2	1.5	-0.2	0.6	0.6	0.4	0.4	0.2	0.2	0.4	0.1	1.4	0.8	0.7	-0.8	0.4	0.4	-0.3	0.0
Gout (self-reported)	0.3	0.4	4.6	-0.1	0.6	-0.8	0.0	-0.1	-0.8	-0.8	-0.0	0.2	0.2	-0.0	-0.0	0.3	2.1	-0.9	-0.8	0.3	-0.2	0.6	-0.0	-0.1	0.4	0.2
Exposure to tobacco smoke outside home	0.3	0.3	1.4	-0.6	0.2	-0.3	-0.7	-0.3	-0.9	0.3	-0.9	0.4	-0.5	-0.7	-0.5	-0.5	0.3	-0.4	-0.8	-0.8	-1.2	0.1	-0.4	-0.6	-0.4	-0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.1	0.6	-0.2	0.4	0.5	1.0	0.9	0.4	0.8	-0.0	0.2	0.7	0.5	0.3	-0.9	0.9	0.5	0.7	0.7	0.5	0.2	0.7	0.4	0.5
Wheeze or whistling in the chest in last year	0.3	0.5	3.9	0.5	-0.2	0.2	0.0	0.5	0.4	2.0	0.6	1.6	0.4	0.7	0.3	-0.8	0.2	0.1	-0.3	-0.1	0.1	0.7	-0.4	0.8	0.4	-0.3
Number of children fathered	0.3	0.4	2.9	0.0	-0.9	0.4	0.1	-0.1	0.8	-0.5	-0.2	-0.2	-0.3	-0.2	0.9	-0.6	-0.7	-0.0	1.7	-0.1	0.3	-1.1	-0.2	-0.0	-0.6	-0.3
Health satisfaction	0.3	0.4	2.4	-0.3	-0.9	-1.5	-0.2	-0.1	0.2	-1.1	-0.2	0.4	0.0	-0.4	-0.5	-0.3	0.5	-0.2	1.6	0.2	-0.1	-0.9	-0.1	-0.2	-0.8	-0.1
Neck or shoulder pain in last month	0.3	0.5	1.7	-0.0	-1.3	-0.2	-0.7	-0.2	-0.1	1.1	-0.3	0.5	0.2	-0.4	-0.5	-1.2	-0.6	-0.3	1.3	-0.6	-0.0	-1.1	-0.4	-0.2	-0.7	-0.9
Medication: Omeprazole	0.3	0.4	2.3	-0.3	-1.1	0.1	-0.1	-0.4	0.5	0.6	-0.4	-0.2	0.0	-0.5	0.5	-0.9	-0.5	-0.1	1.5	-0.5	0.1	-1.2	-1.0	-0.3	-0.7	-0.4
Age at last live birth	0.3	0.5	1.8	-0.7	-1.0	-0.3	-0.9	-0.6	-0.5	-0.6	-0.5	-1.1	-0.5	-0.5	0.2	-0.7	-0.7	-0.2	0.7	-0.5	-0.3	-1.3	-0.6	-0.5	-0.9	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	3.9	-0.4	-0.4	-0.7	0.3	-0.0	0.3	-1.1	0.4	-0.2	-0.2	0.4	0.5	-0.9	-2.0	1.0	-0.4	-0.1	0.1	0.6	0.1	0.3	0.1	0.0
Loneliness, isolation	0.3	0.5	2.7	-1.3	0.4	-1.6	0.1	0.3	0.6	-0.6	0.3	-0.1	-0.4	0.2	-1.4	-0.2	1.0	-0.5	0.6	0.1	-0.6	-0.1	0.4	0.2	-0.9	-0.2
Diabetes diagnosed by doctor	0.3	0.5	2.7	0.6	1.6	0.3	-0.4	0.3	1.4	1.3	0.3	-1.2	-0.1	0.2	0.2	0.7	0.7	-0.7	0.2	0.5	0.5	0.4	0.2	0.3	0.6	0.5
Illnesses of father: None of the above (group 1)	0.3	0.4	1.5	0.2	-0.4	0.8	0.1	-0.5	-1.0	-1.1	-0.2	-0.2	-0.4	-0.3	-0.6	-1.0	-1.2	-0.1	-0.6	-0.7	-0.3	0.1	-0.5	-0.4	0.0	-0.6
Guilty feelings	0.3	0.5	2.5	-0.1	-0.3	-0.8	-0.1	-0.3	-1.6	0.2	-0.7	0.4	-0.2	-0.7	-1.3	-0.6	0.0	-0.3	-0.3	-0.8	-1.0	-0.5	0.5	-0.7	-0.6	-1.0
Pack years of smoking	0.3	0.5	2.5	-0.3	-0.7	-0.4	-1.0	0.4	0.4	1.1	0.3	0.7	1.1	0.1	0.3	0.2	-1.0	1.6	1.0	0.2	0.4	-0.6	0.3	0.4	-0.4	0.5
Depression (Nagel 2018)	0.2	0.3	2.0	-0.3	-0.3	-0.2	0.5	0.5	1.1	1.4	0.6	0.4	0.4	0.5	0.4	-0.3	-0.1	0.6	0.6	0.3	0.4	-0.2	-0.1	0.7	-0.3	0.1
Verbal and Numeric Reasoning (VNR)	0.2	0.6	2.7	-0.4	-0.9	-1.4	-0.2	-0.5	0.3	-0.6	-0.4	-1.1	-0.4	-0.5	0.9	-0.3	-1.4	0.0	1.6	-0.2	0.1	-1.1	-0.3	-0.4	-0.5	-0.4
Mean Putamen Volume	0.2	0.3	1.2	0.2	0.2	0.4	0.4	-0.1	-1.1	-0.9	-0.2	0.1	-0.3	-0.1	-0.2	-0.8	-0.9	0.5	-1.0	-0.7	-0.6	0.0	0.1	-0.0	-0.1	-0.6
Fasting Glucose	0.2	0.2	1.3	-0.0	-0.2	0.0	0.4	-0.1	0.2	0.3	0.3	-0.3	0.6	0.1	1.1	-0.3	-0.5	0.4	0.6	0.2	0.7	0.5	0.8	0.0	0.6	0.3
HbA1C	0.2	0.3	1.1	0.1	0.8	0.5	-0.2	-0.3	-1.0	-0.8	-0.4	0.0	-0.1	-0.4	-0.5	0.2	-0.0	0.2	-0.8	-0.1	-0.2	1.1	-0.2	-0.5	0.7	0.2
Cardiovascular Disease	0.2	0.7	2.5	-0.1	-0.2	-1.1	0.4	0.6	1.4	0.1	1.0	0.2	0.0	0.8	1.2	-0.4	-1.3	1.6	1.0	0.6	0.9	-0.3	0.7	1.2	-0.2	0.4
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.5	-0.1	1.0	-0.1	-1.0	-0.6	0.4	0.5	-0.5	-1.2	-0.4	-0.6	-0.3	0.0	0.5	-1.2	0.1	-0.4	-0.1	-0.5	-0.6	-0.6	-0.1	-0.3
Medication: Co-codamol	0.2	0.2	1.0	0.2	0.1	0.2	0.4	0.7	0.3	1.0	0.2	0.3	0.5	0.2	0.8	0.3	0.6	0.4	0.1	0.4	0.4	-0.2	-0.2	0.3	0.2	0.6
Diabetes (father)	0.2	0.3	1.8	0.2	0.1	-0.7	-0.1	-0.2	0.8	-0.2	0.3	0.4	0.5	0.2	0.0	0.5	1.3	0.1	1.4	0.6	0.5	-0.5	0.2	0.2	-0.2	0.2
Impedance of leg (right)	0.2	1.1	4.6	0.0	0.8	0.7	0.2	1.4	0.1	1.2	0.7	0.5	1.2	0.7	1.2	2.1	1.5	0.8	0.2	1.1	0.8	0.7	1.5	0.8	0.7	1.5
Maternal smoking around birth	0.2	0.3	2.1	0.8	0.1	1.5	-0.2	0.2	0.1	0.7	0.2	-0.1	0.6	0.1	0.9	0.2	-0.7	0.8	-0.7	-0.0	0.6	0.2	0.3	0.2	0.6	0.7
High blood pressure	0.2	0.5	2.0	-0.4	-0.4	-0.9	0.2	0.5	1.4	0.5	0.8	0.9	0.3	0.7	0.5	-0.4	-1.0	1.4	1.1	0.1	0.4	-0.3	0.1	1.1	-0.5	-0.0
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.2	0.8	0.2	0.8	0.3	0.7	-0.1	0.3	0.2	1.1	1.0	0.3	0.9	0.6	-0.0	0.9	-0.6	0.3	0.5	0.7	0.3	0.4	0.9	0.7
Medication: Levothyroxine sodium	0.2	0.4	3.1	1.0	0.3	1.8	-0.5	-0.3	0.1	0.6	-0.2	-1.2	-0.1	-0.2	0.0	0.6	-0.6	-0.1	-0.4	0.0	0.4	-0.1	0.7	-0.3	0.5	0.4
Past tobacco smoking	0.2	0.3	1.1	-0.0	-0.2	0.6	0.6	0.9	0.1	0.1	0.6	0.9	1.0	0.5	0.1	0.5	-0.3	1.0	0.6	0.5	0.6	0.5	-0.3	0.5	0.4	0.8
Hearing difficulty/problems with background noise	0.2	0.3	1.9	0.1	-1.0	0.4	0.0	0.0	0.3	0.5	0.2	1.4	0.8	0.2	0.7	-0.6	-0.5	1.0	0.3	0.0	0.3	-0.8	-0.2	0.3	-0.3	-0.1
Diabetes (self-reported)	0.2	0.3	1.7	0.4	1.3	-0.3	-0.7	-0.1	1.1	1.0	-0.0	-1.3	-0.5	-0.0	-0.1	0.5	0.2	-0.8	0.1	0.2	0.2	0.3	-0.1	0.0	0.4	0.2
Medication: Simvastatin	0.2	0.4	2.8	0.2	1.7	0.2	-0.4	0.1	0.4	0.9	-0.1	-0.1	0.1	-0.0	0.7	0.9	1.3	-0.4	-0.7	0.3	-0.1	0.1	0.6	-0.0	0.2	0.1
Fluid intelligence score	0.2	0.3	1.3	0.5	0.5	-0.0	1.0	0.3	0.5	-0.0	0.5	0.0	0.3	0.4	1.1	0.7	-0.2	0.7	0.5	0.6	0.7	0.3	1.1	0.5	0.5	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	2.3	0.0	-0.8	-0.4	-0.5	-0.6	0.3	0.1	-0.2	-0.1	-0.4	-0.3	-0.5	-0.6	-0.2	-0.2	1.5	0.1	-0.0	-1.4	-0.4	-0.4	-0.9	-0.6
Number of live births	0.2	0.2	1.1	0.6	0.2	0.8	0.2	0.4	-1.0	0.8	-0.3	0.6	0.1	-0.1	0.3	-0.1	-0.1	0.5	-0.8	-0.4	-0.4	0.4	-0.3	-0.0	0.3	0.0
Happiness	0.2	0.3	1.9	0.5	0.2	-1.4	0.6	0.3	-0.1	-1.2	0.0	-0.5	-0.0	0.1	0.5	0.5	0.0	0.6	0.1	0.5	0.2	-0.2	0.7	0.1	0.1	0.6
Qualifications: A levels/AS levels or equivalent	0.2	0.5	1.5	-0.2	-0.1	0.8	-0.7	-1.0	-1.1	-0.8	-0.8	-1.2	-1.2	-0.6	0.2	-0.4	-1.0	-0.7	-0.6	-0.5	-0.9	0.6	-0.1	-0.8	0.1	-0.5
Birth weight of first child	0.2	0.4	2.6	0.7	0.2	1.6	0.6	-0.6	0.5	1.4	-0.3	-0.8	-0.0	-0.3	-0.1	0.2	-0.5	-0.2	0.6	0.2	0.5	0.0	0.8	-0.3	0.5	0.2
Glaucoma (self-reported)	0.2	0.2	1.9	0.4	0.8	0.1	0.3	-0.6	-0.1	0.0	-0.2	-0.2	-0.2	-0.1	-0.5	0.1	0.7	-0.7	-0.8	-0.0	-0.2	0.3	-1.4	-0.2	0.3	-0.2
High blood pressure (siblings)	0.2	0.3	1.5	0.1	0.4	-0.7	0.7	0.3	0.6	0.1	0.6	-0.3	-0.2	0.6	0.2	-0.6	-0.7	0.0	-0.5	-0.0	0.3	0.5	1.2	0.5	0.2	-0.5
Age at first live birth	0.2	0.4	2.8	0.5	0.4	1.7	0.3	-0.4	0.1	0.1	0.1	-1.1	0.3	0.1	1.0	0.6	0.5	-0.1	-0.1	0.5	0.8	-0.6	0.6	-0.0	0.3	0.8
Migraine (self-reported)	0.2	0.3	0.8	0.5	-0.3	0.8	0.3	-0.0	-0.2	-0.5	-0.2	0.2	0.9	-0.2	0.8	0.7	0.2	0.7	0.1	0.6	0.5	-0.4	0.9	-0.2	0.3	0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.2	0.2	1.0	-0.3	0.1	-0.1	-0.2	0.4	0.3	0.5	-0.0	-0.8	-0.6	0.0	0.0	0.4	-1.0	0.8	0.3	0.2	-0.1	0.0	0.9	0.1	-0.3	0.4
Alcohol intake frequency.	0.2	0.4	3.6	-0.2	-0.7	-1.0	-0.2	0.3	0.9	0.9	0.4	0.8	0.5	0.3	-0.0	0.2	-0.2	0.9	1.9	0.4	0.6	-0.4	-0.3	0.4	-0.3	0.2
Chest pain or discomfort	0.2	0.3	1.4	1.2	0.8	-0.7	0.2	0.3	-0.3	0.8	0.1	0.7	0.5	0.3	0.2	-0.2	0.6	-0.0	-0.9	0.1	0.2	0.5	0.0	0.3	0.8	-0.0
Hypertension (Self-reported)	0.2	0.6	2.3	-0.5	-0.3	-1.1	0.2	0.6	1.5	0.6	0.9	1.1	0.2	0.8	0.5	-0.5	-0.9	1.3	1.2	0.2	0.4	-0.2	-0.0	1.1	-0.5	-0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.7	0.5	0.8	-0.3	0.9	0.7	-0.2	-0.0	0.4	0.9	0.2	0.6	0.7	-0.2	-0.4	0.6	-1.0	0.1	0.0	1.3	-0.4	0.6	0.7	0.3
Long-standing illness, disability or infirmity	0.2	0.4	1.7	0.3	-1.1	-0.7	-0.8	-0.7	-0.2	1.0	-0.5	0.4	0.5	-0.7	0.0	-0.5	-0.4	0.0	0.1	-0.4	-0.0	-1.3	-0.4	-0.5	-0.5	-0.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.2	0.2	1.0	-0.2	0.7	0.5	-0.3	0.1	-0.4	0.7	-0.1	1.0	0.5	-0.1	-0.7	0.4	1.0	-0.0	-0.1	-0.1	-0.2	0.5	0.2	-0.2	0.2	-0.2
Mineral and other dietary supplements	0.2	0.3	1.5	0.0	-0.0	0.2	0.2	-0.3	0.9	-0.7	0.3	-0.9	-0.2	0.0	-0.3	0.2	-0.2	0.3	1.2	0.6	0.7	-0.6	0.9	0.0	-0.2	0.5
Medication: Gliclazide	0.2	0.3	1.9	-0.5	1.1	-0.4	-0.5	-0.2	0.5	0.4	-0.0	0.2	0.4	-0.0	-0.0	1.0	1.4	-0.6	-0.1	0.3	-0.2	0.5	-0.2	-0.2	0.1	0.4
Miserableness	0.2	0.4	1.8	-0.7	-0.6	-1.3	-0.6	-0.9	0.5	0.3	-0.3	-0.8	-0.5	-0.5	-1.1	-0.5	-0.8	-0.3	0.7	-0.4	-0.3	-0.8	-0.1	-0.5	-0.8	-0.4
Commuting to job workplace: Public transport	0.2	0.3	1.0	-0.0	0.6	-0.2	-0.1	0.3	0.2	-1.0	0.5	0.3	-0.1	0.6	0.3	0.7	0.3	0.7	-1.0	0.5	-0.1	1.0	0.5	0.6	0.3	0.8
Ever smoked	0.2	0.4	2.5	0.1	0.5	-0.5	-0.3	-0.6	-0.5	0.1	-0.4	-1.1	-1.0	-0.2	-0.2	-0.4	-0.0	-0.8	-1.6	-0.5	-0.6	0.2	0.6	-0.4	0.1	-0.5
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.7	0.5	0.4	1.2	-0.2	-0.4	-1.1	-0.6	-0.5	-0.6	-0.1	-0.4	-0.5	0.5	1.2	-1.3	-1.0	0.1	-0.3	0.5	-0.1	-0.8	0.6	0.1
Heart attack/myocardial infarction (self-reported)	0.2	0.3	2.6	0.0	1.0	-0.4	0.4	0.1	-0.5	0.1	-0.3	-0.4	-0.3	-0.2	0.2	-0.2	-0.5	-0.0	-1.0	-0.6	-0.3	0.3	1.6	-0.1	0.3	-0.3
Heart disease (siblings)	0.2	0.3	1.6	-0.1	0.0	-1.0	0.1	-0.1	0.3	-0.3	-0.1	-1.3	-0.5	-0.3	-0.7	-0.4	-0.1	-0.9	0.4	-0.3	0.3	-0.8	-0.2	-0.2	-0.3	-0.2
Alcohol drinker status: Previous	0.2	0.3	2.0	-0.1	-0.9	-1.4	0.0	0.2	-0.1	-0.1	0.0	0.3	0.1	0.0	-0.4	-0.9	-1.0	0.5	0.6	-0.5	0.1	-0.4	-0.1	0.0	-0.3	-0.5
Intelligence (Savage-Jansen 2018)	0.1	0.4	2.7	-0.1	-0.8	-0.3	-0.2	-0.3	0.7	-0.2	-0.2	-1.1	-0.4	-0.3	0.1	-0.3	-1.2	0.0	1.6	-0.2	0.2	-1.0	0.0	-0.2	-0.5	-0.3
Neuroticism (Nagel 2018)	0.1	0.2	0.9	-0.3	-0.8	-0.1	0.6	0.3	0.1	0.6	0.3	0.6	0.4	0.2	0.1	-0.5	-0.9	0.9	0.8	-0.0	0.0	0.1	0.0	0.3	-0.2	-0.2
Schizophrenia (2018)	0.1	0.3	0.9	-0.6	0.6	-0.6	0.3	0.5	0.3	-0.0	0.4	0.3	0.3	0.5	0.1	0.9	0.9	0.7	0.2	0.6	0.1	0.4	0.7	0.4	-0.0	0.7
Ulcerative Colitis (UC)	0.1	0.3	1.7	-0.2	-0.1	-0.1	0.0	0.2	1.3	1.3	0.4	-0.3	0.1	0.2	0.9	0.1	0.1	0.2	1.0	0.1	0.6	-0.6	0.1	0.3	-0.2	-0.1
Breast Cancer	0.1	0.3	1.3	-0.1	0.6	1.1	0.3	0.4	-0.2	1.1	-0.0	-0.4	0.5	0.0	0.9	0.9	0.5	0.2	-0.2	0.4	0.4	-0.2	1.1	0.0	0.2	0.7
Body Mass Index (BMI) (2010)	0.1	0.1	0.5	0.2	0.5	0.2	0.5	0.5	0.7	0.7	0.3	-0.1	-0.1	0.3	0.0	-0.1	-0.2	0.1	0.3	0.0	0.3	0.2	0.4	0.4	0.2	-0.3
Neuroticism (2016)	0.1	0.2	0.9	0.4	-0.4	0.3	-0.0	-0.7	-0.6	-0.1	-0.7	-0.3	0.1	-0.7	-0.1	-0.5	-0.1	-0.3	-0.1	-0.3	-0.1	-0.9	-0.4	-0.7	-0.2	-0.3
Ulcerative Colitis	0.1	0.1	0.6	-0.4	0.1	-0.4	-0.3	-0.0	0.6	0.8	-0.1	-0.2	0.0	-0.2	0.1	-0.0	0.2	0.0	0.5	-0.0	0.1	-0.6	0.6	-0.2	-0.4	-0.2
Blood Red Count	0.1	1.2	2.6	-0.5	1.1	0.2	0.8	1.1	1.6	1.0	1.6	1.0	0.7	1.6	0.2	1.5	1.0	1.4	-0.8	1.2	0.5	1.3	1.2	1.5	0.4	1.3
Height	0.1	2.3	6.9	1.3	1.1	2.0	2.6	1.7	1.9	0.6	1.6	1.0	0.9	1.6	2.1	1.7	1.1	0.9	0.4	2.0	1.6	1.4	0.5	1.6	1.4	1.8
Systolic Blood Pressure	0.1	0.3	1.4	-0.9	-0.0	1.1	-0.5	0.2	0.4	-0.8	0.2	0.2	0.1	0.2	0.1	0.1	-1.0	1.2	0.3	0.2	-0.0	0.2	1.1	0.4	-0.2	0.3
Allergy or Eczema	0.1	0.2	0.7	0.3	0.1	0.3	0.1	0.5	0.5	-0.2	0.3	0.2	0.4	0.3	0.7	0.8	0.1	0.6	0.4	0.7	0.5	0.4	0.3	0.3	0.5	0.8
Neuroticism	0.1	0.2	1.0	-0.6	-0.6	-0.8	0.6	-0.1	0.4	0.1	0.3	-0.3	-0.2	0.1	-0.3	-0.4	-0.3	0.2	1.0	0.1	0.1	-0.4	0.2	0.2	-0.6	-0.2
Hand grip strength (left)	0.1	0.4	2.2	0.0	0.5	-0.6	1.2	0.4	0.4	0.2	0.6	1.3	0.4	0.6	-0.4	0.0	0.3	0.3	-0.0	0.2	0.1	0.9	1.5	0.6	0.3	-0.3
Average weekly spirits intake	0.1	0.1	0.2	0.3	0.4	-0.4	0.3	-0.3	0.1	-0.5	0.3	0.3	0.2	0.3	0.2	-0.1	0.2	-0.0	-0.1	0.1	0.2	-0.0	-0.4	0.1	0.0	-0.3
Frequency of depressed mood in last 2 weeks	0.1	0.2	0.9	-0.1	0.0	-0.5	0.4	0.5	0.8	0.8	0.5	0.4	0.2	0.3	-0.4	-0.1	-0.0	0.5	0.6	0.2	0.4	-0.2	1.0	0.4	-0.2	0.0
Systolic blood pressure, automated reading	0.1	0.4	1.7	-0.6	0.1	0.8	-0.4	-0.0	0.5	-0.1	0.2	1.1	0.7	0.2	-0.4	1.0	1.3	0.5	1.1	0.8	0.2	-0.3	0.4	0.2	-0.5	0.4
Vitamin and mineral supplements	0.1	0.1	0.6	0.1	0.0	0.3	0.7	0.1	0.8	-0.0	0.6	0.0	-0.0	0.3	-0.2	0.4	0.3	-0.0	0.8	0.5	0.5	-0.2	-0.2	0.3	-0.1	0.2
Leg fat-free mass (left)	0.1	0.6	2.5	1.0	0.8	0.6	1.4	0.9	0.6	0.1	0.9	1.6	0.6	0.9	0.4	-0.3	0.6	0.4	-0.5	0.5	0.5	1.0	-0.6	0.9	0.7	0.1
Hand grip strength (right)	0.1	0.4	1.7	-0.6	0.2	-0.3	0.5	-0.3	-0.4	-0.8	-0.2	0.2	-0.8	-0.1	-1.3	-0.8	-0.7	-0.3	-0.5	-0.7	-0.9	0.7	0.4	-0.1	-0.2	-1.1
Fed-up feelings	0.1	0.2	1.2	-0.4	-0.6	-1.1	-0.0	0.2	0.3	0.4	0.2	-0.2	0.0	0.1	-0.1	-0.3	-1.0	0.9	0.7	-0.0	0.2	-0.6	0.2	0.3	-0.5	0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.7	0.8	0.2	-0.2	0.1	-0.3	0.3	0.8	-0.2	-0.4	-0.2	-0.2	-0.2	-0.4	-0.7	-0.4	-0.3	-0.3	-0.0	-0.4	-0.4	-0.2	0.1	-0.4
Multivitamins +/- minerals	0.1	0.2	1.1	-0.1	-0.3	0.1	-0.2	0.2	-0.8	-0.4	-0.3	-0.1	-0.2	-0.1	0.0	-0.5	-0.6	0.0	-1.0	-0.4	-0.5	0.5	-0.1	-0.0	0.2	0.0
Sitting height	0.1	0.4	2.3	0.0	0.8	0.8	0.8	0.4	-0.1	0.8	0.0	-0.1	-1.5	0.1	0.2	-0.6	-0.9	-0.3	-0.3	-0.3	-0.7	1.2	-0.8	0.2	0.1	-0.6
Impedance of leg (left)	0.1	0.5	3.0	-0.3	0.6	0.2	-0.1	0.8	-0.3	0.8	0.3	0.3	0.7	0.3	0.7	1.7	0.8	0.6	-0.1	0.7	0.3	0.7	1.4	0.4	0.6	1.2
Leg predicted mass (left)	0.1	0.6	2.4	1.0	0.8	0.5	1.3	0.8	0.6	0.1	0.8	1.5	0.6	0.9	0.4	-0.3	0.6	0.4	-0.6	0.4	0.5	1.0	-0.5	0.8	0.7	0.0
Forced vital capacity (FVC)	0.1	0.3	0.6	0.3	0.8	0.7	0.8	0.7	0.7	-0.2	0.8	0.2	-0.6	0.7	0.8	0.1	0.7	-0.4	-0.3	0.6	0.2	0.8	-0.3	0.6	0.3	-0.2
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.7	0.1	0.0	-0.7	0.2	0.4	-0.3	-0.2	0.2	0.7	0.8	0.2	-0.0	-0.2	0.7	0.1	-0.2	0.2	0.3	0.4	0.3	0.2	0.4	0.1
Neuroticism score	0.1	0.2	1.1	-0.4	-0.9	-0.5	0.1	-0.2	0.1	0.2	0.0	-0.4	-0.2	-0.1	-0.5	-0.8	-1.0	0.2	0.9	-0.2	-0.0	-0.7	-0.0	-0.1	-0.6	-0.5
Impedance of arm (right)	0.1	0.3	1.3	0.2	-0.5	0.4	-0.7	-0.2	-0.2	0.7	-0.2	-1.2	0.1	-0.1	0.8	0.8	-0.3	0.1	-0.0	0.1	0.4	-0.6	1.0	-0.0	0.1	0.8
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.4	0.7	0.6	0.5	1.1	0.9	1.1	-0.1	1.1	0.6	-0.1	1.0	1.2	0.2	0.5	0.1	0.2	0.8	0.8	0.7	0.2	0.9	0.5	-0.1
Medication: Cholesterol lowering	0.1	0.2	0.7	-0.8	0.1	-0.2	-0.5	-0.2	0.7	0.2	-0.1	-0.5	-0.1	-0.0	0.4	0.1	0.2	-0.3	0.8	-0.2	-0.1	-0.7	0.2	0.1	-0.7	-0.3
Medication: Lansoprazole	0.1	0.1	0.3	-0.4	0.5	0.0	-0.4	-0.1	-0.5	0.5	0.0	0.6	0.5	0.0	-0.2	0.0	0.2	0.0	0.5	0.1	0.1	0.1	0.3	-0.1	-0.0	0.1
Peak expiratory flow (PEF)	0.1	0.3	1.7	-0.2	-0.5	-0.1	-0.3	-0.4	-0.2	-1.3	-0.2	0.4	-0.9	-0.2	-0.2	-0.8	-0.3	-0.8	0.3	-0.6	-0.5	-0.2	-0.8	-0.3	-0.4	-1.1
Forced vital capacity (FVC), Best measure	0.1	0.5	1.3	0.5	0.8	0.7	1.1	1.0	0.4	0.5	0.9	1.0	0.2	0.9	0.9	0.4	0.6	0.4	-0.7	0.6	0.3	1.0	0.2	0.9	0.6	0.1
Arm fat-free mass (right)	0.1	0.6	3.4	0.4	1.2	0.1	1.4	0.9	0.7	-0.0	0.7	1.8	0.4	0.8	0.3	0.0	1.1	0.2	-0.2	0.6	0.1	1.3	-0.6	0.7	0.5	-0.0
Emphysema/chronic bronchitis	0.1	0.1	0.4	0.6	-0.0	-0.6	-0.1	-0.6	0.4	0.4	-0.1	-0.3	-0.1	-0.2	-0.4	-0.6	-0.2	-0.2	-0.1	-0.3	0.1	-0.5	0.4	-0.1	-0.0	-0.3
Medication: Ibuprofen	0.1	0.1	0.9	-0.3	0.5	0.0	0.0	0.3	-0.1	0.1	0.3	0.7	0.4	0.2	-0.9	0.7	0.6	0.2	0.2	0.3	-0.1	0.4	-0.1	0.1	-0.1	0.3
Arm predicted mass (right)	0.1	0.6	3.2	0.5	1.2	0.3	1.4	0.9	0.6	-0.0	0.7	1.8	0.4	0.8	0.3	-0.0	0.8	0.4	-0.5	0.5	0.1	1.4	-0.5	0.7	0.6	-0.0
Suffer from ‘nerves’	0.1	0.2	0.7	-0.4	-0.2	-0.7	0.7	0.4	-0.1	0.1	0.3	0.4	0.0	0.4	-0.4	-0.7	-0.5	0.1	-0.2	-0.1	-0.1	0.8	0.5	0.3	0.2	-0.4
Commuting to job workplace: Car/motor vehicle	0.1	0.1	0.8	0.1	0.8	0.9	0.5	0.2	-0.4	0.6	-0.2	0.2	0.2	-0.1	0.2	0.2	-0.0	-0.0	0.1	0.0	0.1	-0.1	0.1	-0.1	0.2	-0.1
Leg fat-free mass (right)	0.1	0.3	1.6	0.8	0.5	0.1	1.0	0.3	0.4	-0.3	0.5	1.2	0.1	0.5	-0.0	-0.7	-0.1	0.2	-0.5	0.1	0.0	0.8	-0.7	0.4	0.4	-0.3
Mood swings	0.1	0.2	2.7	0.1	-0.7	-0.4	-0.2	-0.0	0.3	0.5	0.1	-0.6	-0.4	0.1	-0.3	-0.4	-1.6	0.8	-0.1	-0.1	-0.2	-0.1	0.6	0.1	-0.3	-0.1
Friendships satisfaction	0.1	0.2	1.2	0.0	-0.2	-0.3	0.2	-0.0	0.2	0.3	-0.1	-0.1	0.1	-0.1	0.4	0.4	0.2	0.5	0.7	0.2	0.2	-0.8	1.1	0.1	-0.4	0.3
Leg predicted mass (right)	0.1	0.3	1.6	0.8	0.5	0.2	1.0	0.4	0.4	-0.3	0.5	1.3	0.2	0.5	0.0	-0.7	-0.1	0.2	-0.5	0.1	0.1	0.9	-0.7	0.5	0.5	-0.3
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.7	-0.1	-0.3	0.3	-0.6	0.2	-0.1	-0.1	-0.3	0.5	0.2	-0.3	-0.4	0.1	0.5	-0.2	0.6	0.2	-0.0	-0.4	-0.8	-0.3	-0.2	-0.0
Medication: Blood pressure	0.1	0.2	1.2	-0.0	-0.2	-0.9	-0.5	-0.5	-0.3	-0.3	-0.2	0.3	-0.3	-0.3	-1.1	-0.8	-0.5	-0.3	-0.1	-0.5	-0.4	-0.1	0.4	-0.3	-0.3	-0.7
Supplements: Fish oil (including cod liver oil)	0.1	0.2	0.7	0.0	0.1	-0.2	0.1	0.3	-0.3	0.8	-0.1	0.7	0.4	0.2	0.6	-0.1	0.4	-0.4	-0.8	-0.1	-0.2	0.6	-0.5	0.1	0.4	-0.4
Medication: Bendroflumethiazide	0.1	0.2	0.9	-0.2	0.9	-0.3	-0.1	0.2	0.4	0.4	0.4	0.9	0.3	0.5	0.2	0.2	0.8	0.0	-0.3	0.2	0.1	0.2	0.6	0.4	0.0	0.0
Alcohol drinker status: Never	0.1	0.1	0.6	0.0	-0.2	-0.4	-0.2	0.3	-0.7	-0.1	0.2	0.5	0.8	0.1	-0.1	-0.1	-0.1	0.7	-0.1	0.2	0.3	0.0	0.7	0.1	0.1	0.2
Basal metabolic rate	0.1	0.4	2.3	0.4	0.7	0.3	1.2	0.7	0.4	-0.0	0.6	1.5	0.3	0.6	0.1	-0.3	0.4	0.3	-0.4	0.2	0.0	1.1	-0.5	0.6	0.4	-0.2
Arm fat-free mass (left)	0.1	0.4	2.8	0.1	0.8	-0.0	1.2	0.6	0.4	-0.0	0.5	1.7	0.1	0.6	-0.0	-0.3	0.6	0.1	-0.3	0.2	-0.1	1.1	-0.8	0.5	0.3	-0.3
Age started oral contraceptive pill	0.1	0.1	1.2	0.2	-0.5	-1.1	0.4	-0.5	0.1	-0.4	0.0	-0.2	-0.1	-0.1	-0.4	0.0	-0.1	0.2	0.3	0.1	0.0	-0.8	0.3	-0.1	-0.4	-0.0
Cholesterol lowering medication	0.1	0.2	1.0	0.7	0.1	-0.8	-0.6	-0.6	0.3	0.1	-0.3	-0.0	0.1	-0.4	0.5	0.2	0.2	-0.0	0.7	0.3	0.3	-1.0	-0.0	-0.4	-0.1	0.1
Impedance of whole body	0.1	0.4	2.2	0.1	0.3	0.1	-0.1	0.6	-0.1	0.6	0.3	-0.1	0.6	0.3	1.0	1.5	0.9	0.3	-0.0	0.6	0.5	0.3	0.8	0.4	0.5	1.1
Arm predicted mass (left)	0.1	0.4	2.5	0.0	0.8	0.0	1.1	0.7	0.5	-0.0	0.5	1.6	0.2	0.6	-0.0	-0.1	0.8	0.1	-0.2	0.3	-0.1	1.2	-0.6	0.5	0.3	-0.2
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Platelet Count	0.0	0.6	3.8	1.1	0.5	1.8	0.1	-0.3	-1.7	-0.1	-0.5	-0.4	-0.4	-0.3	0.2	-0.3	-0.2	0.0	-1.9	-0.2	-0.3	-0.4	-0.2	-0.5	0.3	-0.2
BMI	0.0	0.1	0.9	0.6	0.3	0.3	0.3	0.1	-0.3	-0.6	0.2	0.6	0.3	0.2	-0.4	-0.2	0.2	0.1	-0.6	0.2	0.2	0.3	-1.0	-0.0	0.3	0.0
Lung FEV1/FVC ratio	0.0	0.2	1.0	0.7	0.2	-1.0	0.7	0.1	0.5	-0.1	0.1	0.0	0.3	-0.0	-0.3	-0.1	-0.3	-0.2	0.4	-0.1	0.5	0.1	1.0	-0.0	0.6	-0.7
Lung FVC	0.0	0.2	1.2	-0.2	-0.3	-0.1	-0.3	-0.1	1.0	0.5	0.1	-0.6	-0.6	0.0	0.4	0.2	0.5	-0.3	1.1	0.5	0.0	-0.8	-0.6	0.0	-0.6	0.1
Hair Pigment	0.0	0.7	2.3	0.3	-1.1	0.7	0.2	1.0	0.9	-0.3	1.0	0.6	1.2	0.9	1.5	0.7	-0.4	1.2	0.1	1.1	1.0	-0.6	-0.1	0.5	0.0	0.9
Tanning	0.0	0.6	3.2	0.1	0.5	0.9	-0.2	-0.5	-0.7	-1.6	-0.5	-0.1	-0.1	-0.4	-0.5	0.3	1.2	-0.9	-1.3	-0.1	-0.7	-0.2	-1.8	-0.5	-0.1	-0.2
Trunk fat-free mass	0.0	0.2	0.7	-0.4	0.2	0.1	0.5	-0.0	-0.2	-0.6	-0.4	0.5	-0.7	-0.2	-0.4	-0.7	-0.3	-0.3	-0.3	-0.5	-0.8	0.4	-0.7	-0.3	-0.3	-0.7
Impedance of arm (left)	0.0	0.2	0.7	0.2	-0.2	-0.2	-0.4	0.1	-0.0	0.3	0.1	-0.7	0.2	0.1	0.6	0.8	0.1	0.1	-0.2	0.2	0.4	-0.2	0.8	0.2	0.3	0.7
Trunk predicted mass	0.0	0.2	0.7	-0.4	0.1	0.1	0.5	-0.0	-0.1	-0.6	-0.4	0.5	-0.7	-0.2	-0.4	-0.7	-0.4	-0.4	-0.2	-0.5	-0.8	0.4	-0.7	-0.3	-0.3	-0.7
Standing height	0.0	0.2	0.8	-0.3	0.5	0.1	0.5	0.1	-0.3	-0.6	-0.4	-0.1	-0.9	-0.2	0.4	-0.0	0.3	-0.8	-0.6	-0.2	-0.7	0.4	-0.7	-0.2	-0.1	-0.3
Headache pain in last month	0.0	0.1	0.3	0.3	-0.5	0.2	0.1	0.4	-0.1	0.1	-0.2	0.1	-0.2	-0.3	0.1	-0.0	-0.2	0.3	0.4	0.0	0.2	-0.4	0.1	-0.0	-0.1	0.2
Comparative height size at age 10	0.0	0.2	1.5	0.0	0.5	-0.3	0.3	0.0	1.2	0.4	0.1	-0.2	-0.6	0.2	0.2	0.1	0.1	-0.7	0.5	0.2	0.2	0.3	-0.1	0.0	0.1	-0.4
Whole body fat-free mass	0.0	0.2	1.1	0.1	0.4	0.2	0.9	0.3	0.2	-0.3	0.2	1.1	-0.2	0.3	-0.1	-0.6	0.1	-0.0	-0.3	-0.1	-0.3	0.7	-0.7	0.2	0.1	-0.5
Whole body water mass	0.0	0.2	1.4	0.3	0.6	0.2	1.1	0.5	0.3	-0.2	0.3	1.2	-0.0	0.4	0.1	-0.5	0.1	0.1	-0.4	0.1	-0.1	0.9	-0.5	0.3	0.3	-0.3

Hub : Genes

VNN2

Models

Trait associations