[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) :

chr6:151,118,271-153,120,904

Best TWAS P=2.84e-93 · Best GWAS P=4.67e-76 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ESR1 0.19 0.10 enet 36 0.10 2.2e-12 11.7 -9.0 2.4e-19 -0.03 1.00 0.00 TRUE
2 METSIM Adipose CCDC170 0.14 0.02 blup 621 0.07 6.1e-11 -1.9 -9.8 1.1e-22 0.35 0.99 0.00 FALSE
3 ROSMAP Brain Pre-frontal Cortex CCDC170 0.20 0.06 lasso 10 0.19 7.2e-24 -5.9 -6.0 1.5e-09 0.53 0.11 0.89 TRUE
4 The Cancer Genome Atlas Bladder Urothelial Carcinoma C6orf97 0.05 0.00 blup 133 0.03 1.3e-03 -18.4 -18.4 2.6e-75 0.80 0.01 0.87 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma C6orf97 0.01 0.01 enet 7 0.01 5.3e-03 -9.6 -17.3 4.4e-67 0.82 0.01 0.94 FALSE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C6orf97 0.08 0.02 blup 133 0.07 6.2e-08 -10.2 -14.1 5.3e-45 0.68 0.02 0.98 TRUE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C6orf97 0.06 0.05 lasso 3 0.08 6.9e-09 -10.9 -12.8 1.5e-37 0.58 0.22 0.76 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C6orf97 0.18 0.06 lasso 4 0.05 1.1e-03 -5.9 -7.4 1.2e-13 0.49 0.33 0.32 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma C6orf97 0.08 0.04 blup 133 0.09 1.2e-10 -18.4 -15.7 2.1e-55 0.78 0.00 1.00 TRUE
10 The Cancer Genome Atlas Brain Lower Grade Glioma RMND1 0.11 0.01 blup 57 0.04 1.5e-05 2.9 5.3 1.2e-07 0.03 0.56 0.01 FALSE
11 The Cancer Genome Atlas Lung Adenocarcinoma C6orf97 0.07 0.03 lasso 5 0.05 1.7e-06 -5.9 -13.3 3.9e-40 0.71 0.01 0.97 TRUE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C6orf97 0.14 0.01 blup 133 0.08 5.2e-06 -18.4 -12.8 2.6e-37 0.74 0.00 0.94 FALSE
13 The Cancer Genome Atlas Pancreatic Adenocarcinoma C6orf97 0.23 0.10 lasso 11 0.11 1.8e-05 -18.4 -20.5 2.8e-93 0.87 0.00 0.99 TRUE
14 The Cancer Genome Atlas Prostate Adenocarcinoma C6orf97 0.10 0.05 blup 133 0.06 2.6e-07 -18.4 -11.6 3.3e-31 0.72 0.00 1.00 FALSE
15 The Cancer Genome Atlas Stomach Adenocarcinoma C6orf97 0.13 0.02 blup 133 0.05 2.8e-04 -10.2 -12.1 1.9e-33 0.63 0.01 0.90 TRUE
16 The Cancer Genome Atlas Testicular Germ Cell Tumors RMND1 0.19 0.06 blup 58 0.10 1.6e-04 -4.6 5.9 4.1e-09 0.10 0.15 0.14 TRUE
17 The Cancer Genome Atlas Thyroid Carcinoma C6orf97 0.08 0.02 lasso 4 0.06 3.4e-06 -17.6 -15.6 1.3e-54 0.85 0.01 0.98 FALSE