TWAS hub - ESR1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.185	0.043	1.9e-06	0.099	0.061	0.102	-0.002	-0.002	4.4e-12	6.1e-08	2.2e-12	0.77	0.75

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1
Heel T-Score	50.8	404.0	404.0	-20.1
Heel bone mineral density (BMD) T-score, automated (left)	35.6	80.8	80.8	-9.0
Heel bone mineral density (BMD) T-score, automated (right)	34.6	79.2	79.2	-8.9
Wheeze or whistling in the chest in last year	7.4	13.2	13.2	3.6
Exposure to tobacco smoke at home	7.3	8.2	8.2	2.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	6.2	7.3	7.3	2.7
Systolic blood pressure, automated reading	6.1	17.6	17.6	4.2
Townsend deprivation index at recruitment	6.1	8.6	8.6	2.9
Osteoporosis (self-reported)	5.8	7.2	7.2	2.7
Supplements: Calcium	5.8	6.3	6.3	2.5
Smoking status: Current	5.7	9.0	9.0	3.0
Systolic Blood Pressure	5.5	27.5	27.5	5.2
Unable to work because of sickness or disability	5.3	6.8	6.8	2.6
Current tobacco smoking	4.8	7.9	7.9	2.8
Number of full sisters	4.8	5.8	5.8	2.4
Myopia	4.6	6.7	6.7	-2.6
High blood pressure	4.3	12.0	12.0	3.5
Had other major operations	4.0	4.9	4.9	-2.2
Maternal smoking around birth	3.9	5.6	5.6	2.4
Breastfed as a baby	3.9	4.8	4.8	-2.2
Medication: Ramipril	3.7	4.7	4.7	2.2
Medication: Atorvastatin	3.7	4.6	4.6	2.1
Vascular/heart problems diagnosed by doctor	3.6	9.8	9.8	-3.1
Knee pain experienced in last month	3.5	5.4	5.4	-2.3
Multivitamins +/- minerals	3.3	4.2	4.2	2.0
Peak expiratory flow (PEF)	3.3	7.8	7.8	-2.8
Tinnitus: Yes, but not now, but have in the past	3.2	3.4	3.4	1.8
Vitamin and mineral supplements	3.1	4.2	4.2	-2.0
Cardiovascular Disease	3.0	9.9	9.9	3.1
Serious illness, injury or assault to yourself	3.0	3.6	3.6	1.9
Qualifications: O levels/GCSEs or equivalent	3.0	4.7	4.7	-2.2
Number of incorrect matches in round	2.9	4.9	4.9	2.2
Medication: Aspirin	2.9	3.9	3.9	-2.0
Migraine (self-reported)	2.8	3.5	3.5	-1.9
Qualifications: nursing, teaching	2.8	4.4	4.4	-2.1
Illness, injury, bereavement, stress in last 2 years	2.7	3.3	3.3	-1.8
Qualifications: A levels/AS levels or equivalent	2.6	5.9	5.9	-2.4
Hypertension (Self-reported)	2.6	7.1	7.1	2.7
HbA1C	2.5	2.7	2.7	1.7
Qualifications: College or University degree	2.5	7.7	7.7	-2.8
Medication: Aspirin	2.5	3.2	3.2	-1.8
Average weekly beer plus cider intake	2.5	3.6	3.6	1.9
Fractured/broken bones in last 5 years	2.5	3.2	3.2	1.8
Forced expiratory volume in 1-second (FEV1), Best measure	2.4	7.7	7.7	-2.8
Number of self-reported non-cancer illnesses	2.4	4.1	4.1	2.0
Hypothyroidism (self reported)	2.3	5.4	5.4	-2.3
Fluid intelligence score	2.3	4.7	4.7	-2.2
Frequency of tenseness / restlessness in last 2 weeks	2.2	3.4	3.4	1.8
Prospective memory result	2.2	2.7	2.7	1.6
Ever had stillbirth, spontaneous miscarriage or termination	2.2	2.4	2.4	-1.6
Risk taking	2.2	3.2	3.2	1.8
Ever had prostate specific antigen (PSA) test	2.2	2.5	2.5	-1.6
Pain experienced in last month	2.2	3.6	3.6	1.9
Chronotype (morning person)	2.1	5.0	5.0	-2.2
Diabetes (father)	2.1	2.7	2.7	-1.6
Financial difficulties in last 2 years	2.1	2.9	2.9	1.7
Financial situation satisfaction	2.1	2.6	2.6	1.6
Medication: Omeprazole (e.g. Zanprol)	2.1	2.5	2.5	1.6
Taking other prescription medications	2.0	3.1	3.1	1.8
Medication: Omeprazole	2.0	2.3	2.3	1.5
Schizophrenia vs Biploar Disorder	1.9	2.5	2.5	1.6
Friendships satisfaction	1.9	2.3	2.3	-1.5
Smoking Status	1.8	4.3	4.3	2.1
Relative age of first facial hair	1.8	3.8	3.8	-1.9
Mood swings	1.8	3.3	3.3	1.8
Medication for hormone replacement therapy	1.7	2.0	2.0	1.4
Chronic bronchitis/emphysema (father)	1.7	2.0	2.0	1.4
Basal cell carcinoma (self-reported)	1.7	2.0	2.0	1.4
Gout (self-reported)	1.6	2.2	2.2	1.5
Forced vital capacity (FVC), Best measure	1.6	5.8	5.8	-2.4
Number of full brothers	1.6	2.0	2.0	1.4
Angina (self-reported)	1.6	2.1	2.1	-1.5
Mother’s age at death	1.6	2.0	2.0	-1.4
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	1.8	-1.3
Hair/balding pattern: Pattern 4	1.5	3.7	3.7	-1.9
Medication for cholesterol, blood pressure or diabetes	1.5	2.5	2.5	-1.6
Asthma (self-reported)	1.5	3.0	3.0	1.7
Ever taken oral contraceptive pill	1.5	1.7	1.7	1.3
Age at First Birth	1.4	2.0	2.0	1.4
Qualifications: None of the above	1.4	3.1	3.1	1.8
Depression (self-reported)	1.4	1.7	1.7	1.3
Number of children fathered	1.4	1.6	1.6	-1.2
Commuting to job workplace: Car/motor vehicle	1.4	1.6	1.6	1.3
Medication for cholesterol	1.4	2.2	2.2	-1.5
Wears glasses or contact lenses	1.4	1.6	1.6	-1.3
Hearing aid user	1.4	1.6	1.6	1.3
Commuting to job workplace: Cycle	1.4	1.6	1.6	1.3
Crohns Disease (2012)	1.3	2.0	2.0	-1.4
Medication: Lansoprazole	1.3	1.5	1.5	1.2
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.8	2.8	-1.7
Guilty feelings	1.3	2.0	2.0	1.4
Medication: Lisinopril	1.3	1.7	1.7	-1.3
Average weekly spirits intake	1.2	1.5	1.5	1.2
Angina	1.2	1.5	1.5	-1.2
Age when periods started (menarche)	1.2	3.0	3.0	1.7
Illnesses of siblings	1.2	1.7	1.7	-1.3
Forced expiratory volume in 1-second (FEV1)	1.2	4.2	4.2	-2.0
Worry too long after embarrassment	1.2	2.1	2.1	1.4
Pulse rate, automated reading	1.2	3.9	3.9	2.0
Eye problems/disorders: Cataract	1.2	1.4	1.4	-1.2
LDL Cholesterol	1.1	1.7	1.7	-1.3
Diastolic blood pressure, automated reading	1.1	3.3	3.3	1.8
Medication: Metformin	1.0	1.4	1.4	-1.2
Sitting height	1.0	7.1	7.1	-2.7
Medication: Simvastatin	1.0	1.5	1.5	-1.2
Family relationship satisfaction	1.0	1.2	1.2	-1.1
Cholesterol lowering medication	1.0	1.4	1.4	-1.2
Bipolar Disorder (2018)	0.9	1.4	1.4	-1.2
Depressed Affect (Nagel 2018)	0.9	1.9	1.9	1.4
Neuroticism (2016)	0.9	1.2	1.2	-1.1
Neuroticism	0.9	2.1	2.1	1.5
Frequency of depressed mood in last 2 weeks	0.9	1.3	1.3	1.1
Happiness	0.9	1.1	1.1	-1.0
Asthma	0.9	1.7	1.7	1.3
Loud music exposure frequency	0.9	1.0	1.0	1.0
Shortness of breath walking on level ground	0.9	1.1	1.1	1.0
Overall health rating	0.9	1.9	1.9	1.4
Supplements: Fish oil (including cod liver oil)	0.9	1.2	1.2	-1.1
Medication: Bendroflumethiazide	0.9	1.4	1.4	1.2
Verbal and Numeric Reasoning (VNR)	0.8	2.0	2.0	-1.4
Lupus	0.8	1.1	1.1	-1.1
Blood Platelet Count	0.8	9.4	9.4	3.1
Average weekly fortified wine intake	0.8	0.9	0.9	1.0
Fed-up feelings	0.8	1.5	1.5	1.2
Mouth/teeth dental problems	0.8	1.2	1.2	1.1
Suffer from ‘nerves’	0.8	1.3	1.3	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	1.8	-1.3
Average weekly champagne plus white wine intake	0.8	1.1	1.1	1.0
Coronary Artery Disease (CAD)	0.7	0.8	0.8	-0.9
Mean Putamen Volume	0.7	0.9	0.9	0.9
High blood pressure (mother)	0.7	1.0	1.0	1.0
Neuroticism score	0.7	1.5	1.5	1.2
Impedance of arm (right)	0.7	3.1	3.1	1.8
Age at first live birth	0.7	1.2	1.2	-1.1
Ulcerative Colitis (UC)	0.6	1.1	1.1	1.0
Rheumatoid Arthritis	0.6	0.8	0.8	-0.9
Pack years adult smoking proportion	0.6	0.9	0.9	0.9
Past tobacco smoking	0.6	1.2	1.2	-1.1
Hearing difficulty/problems with background noise	0.6	0.9	0.9	-1.0
Trunk fat-free mass	0.6	3.6	3.6	-1.9
Pulse wave Arterial Stiffness index	0.6	0.7	0.7	-0.8
Impedance of arm (left)	0.6	2.8	2.8	1.7
Trunk predicted mass	0.6	3.5	3.5	-1.9
Glaucoma (self-reported)	0.6	0.7	0.7	0.8
Hypothyroidism/myxoedema (self-reported)	0.6	1.1	1.1	-1.0
Medication: Blood pressure	0.6	1.1	1.1	1.0
Mean time to correctly identify matches	0.6	1.2	1.2	1.1
Illnesses of father: Heart disease	0.6	0.8	0.8	-0.9
Whole body fat-free mass	0.6	3.3	3.3	-1.8
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	1.0	-1.0
Breast cancer (self-reported)	0.6	0.7	0.7	-0.8
Medication: Blood pressure	0.6	1.1	1.1	1.1
Arm fat-free mass (left)	0.6	3.0	3.0	-1.7
Impedance of whole body	0.6	2.9	2.9	1.7
Alzheimer’s Disease (including proxy)	0.5	0.7	0.7	0.9
Body Mass Index (BMI) (2010)	0.5	0.7	0.7	0.8
Worrier / anxious feelings	0.5	0.9	0.9	0.9
Number of live births	0.5	0.6	0.6	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	0.7	-0.8
Chronic bronchitis/emphysema (mother)	0.5	0.6	0.6	0.8
Arm fat-free mass (right)	0.5	2.4	2.4	-1.5
Arm predicted mass (right)	0.5	2.3	2.3	-1.5
Loneliness, isolation	0.5	0.7	0.7	0.8
Whole body water mass	0.5	3.0	3.0	-1.7
Arm predicted mass (left)	0.5	2.5	2.5	-1.6
Irritable Bowel Disease (IBD)	0.4	0.9	0.9	1.0
Blood White Count	0.4	3.2	3.2	1.8
Height	0.4	7.6	7.6	-2.8
Lung FEV1/FVC ratio	0.4	2.3	2.3	-1.5
Impedance of leg (right)	0.4	1.9	1.9	1.4
Leg predicted mass (left)	0.4	1.9	1.9	-1.4
Forced vital capacity (FVC)	0.4	1.7	1.7	-1.3
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	0.5	0.7
Falls in the last year	0.4	0.5	0.5	0.7
Illnesses of mother	0.4	0.5	0.5	-0.7
Tense / ‘highly strung’	0.4	0.6	0.6	0.8
Exposure to tobacco smoke outside home	0.4	0.5	0.5	0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.5	0.5	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	0.4	-0.7
Smoking status: Previous	0.4	0.6	0.6	0.8
Leg fat-free mass (right)	0.4	2.2	2.2	-1.5
Leg predicted mass (right)	0.4	2.3	2.3	-1.5
Basal metabolic rate	0.4	2.5	2.5	-1.6
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	0.5	-0.7
Pack years of smoking	0.4	0.6	0.6	0.8
Bipolar Disorder or Schizophrenia	0.3	0.8	0.8	-0.9
Alzheimer’s Disease (in father)	0.3	0.3	0.3	0.5
Reaction Time	0.3	0.6	0.6	0.7
Primary Biliary Cirrhosis	0.3	0.4	0.4	-0.6
BMI	0.3	1.9	1.9	-1.4
Waist Hip Ratio (WHR)	0.3	1.2	1.2	-1.1
Respiratory disease	0.3	0.7	0.7	0.8
Other serious medical condition/disability diagnosed by doctor	0.3	0.3	0.3	-0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.3	0.6
Diabetes (mother)	0.3	0.4	0.4	-0.6
Severe depression (siblings)	0.3	0.3	0.3	0.6
Leg fat-free mass (left)	0.3	1.8	1.8	-1.4
Hayfever, allergic rhinitis or eczema	0.3	0.7	0.7	-0.8
Supplements: Glucosamine	0.3	0.4	0.4	-0.7
Impedance of leg (left)	0.3	1.7	1.7	1.3
Heart attack	0.3	0.4	0.4	0.6
Father’s age at death	0.3	0.4	0.4	0.6
Medication: Cholesterol lowering	0.3	0.5	0.5	0.7
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	0.4	-0.6
Medication: Ventolin 100micrograms inhaler	0.3	0.3	0.3	0.6
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.3	-0.6
Long-standing illness, disability or infirmity	0.3	0.5	0.5	0.7
Illnesses of father: None of the above (group 1)	0.3	0.4	0.4	-0.6
Age started oral contraceptive pill	0.3	0.4	0.4	0.7
Ever depressed for a whole week	0.3	0.4	0.4	-0.6
Heart disease (siblings)	0.3	0.4	0.4	0.6
Depression (Nagel 2018)	0.2	0.2	0.2	0.5
Intelligence (Savage-Jansen 2018)	0.2	0.6	0.6	-0.8
Neuroticism (Nagel 2018)	0.2	0.4	0.4	0.6
Major Depression (MDD)	0.2	0.3	0.3	-0.5
Triglycerides	0.2	0.3	0.3	0.5
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.4	-0.6
Lung FVC	0.2	0.8	0.8	0.9
Trunk fat percentage	0.2	0.7	0.7	0.8
Relative age voice broke	0.2	0.3	0.3	-0.5
Had menopause	0.2	0.2	0.2	-0.5
Weight	0.2	0.9	0.9	-1.0
Pulse rate	0.2	0.4	0.4	-0.6
Standing height	0.2	2.4	2.4	-1.5
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.3	0.5
Blood clot in the leg (DVT)	0.2	0.3	0.3	-0.5
Birth weight	0.2	0.4	0.4	-0.6
High blood pressure (siblings)	0.2	0.2	0.2	0.5
Body fat percentage	0.2	0.7	0.7	0.8
Leg fat percentage (right)	0.2	0.6	0.6	0.7
Pulse wave peak to peak time	0.2	0.3	0.3	0.5
Eye problems/disorders: None of the above	0.2	0.2	0.2	0.5
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.2	0.5
Medication for pain relief, constipation, heartburn	0.2	0.3	0.3	0.6
Medication: Ibuprofen	0.2	0.2	0.2	-0.5
Arm fat percentage (left)	0.2	0.7	0.7	0.8
Commuting to job workplace: Walk	0.2	0.2	0.2	-0.4
Mineral and other dietary supplements	0.2	0.3	0.3	-0.6
Tinnitus: Yes, now most or all of the time	0.2	0.2	0.2	0.4
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.2	0.5
Alcohol drinker status: Previous	0.2	0.2	0.2	0.5
Crohns Disease (2017)	0.1	0.3	0.3	0.5
Bipolar Disorder (2011)	0.1	0.1	0.1	-0.3
Fasting Glucose	0.1	0.1	0.1	0.3
Ulcerative Colitis	0.1	0.1	0.1	0.4
Blood Eosinophil Count	0.1	0.9	0.9	0.9
Blood Red Count	0.1	0.5	0.5	-0.7
Allergy or Eczema	0.1	0.3	0.3	-0.5
Hair Pigment	0.1	1.8	1.8	1.4
Hand grip strength (left)	0.1	0.1	0.1	-0.4
Number of treatments/medications taken	0.1	0.1	0.1	0.4
Sensitivity / hurt feelings	0.1	0.1	0.1	0.4
Hearing difficulty/problems: Yes	0.1	0.1	0.1	-0.3
Ever used hormone-replacement therapy (HRT)	0.1	0.1	0.1	0.3
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	0.4
Stomach or abdominal pain in last month	0.1	0.1	0.1	0.4
Medication: Atenolol	0.1	0.1	0.1	0.3
Medication: Levothyroxine sodium	0.1	0.1	0.1	0.3
Alcohol usually taken with meals	0.1	0.2	0.2	-0.4
Diabetes (self-reported)	0.1	0.2	0.2	-0.4
Arm fat percentage (right)	0.1	0.6	0.6	0.8
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.1	-0.3
Noisy workplace	0.1	0.2	0.2	0.4
Mouth/teeth dental problems: Dentures	0.1	0.1	0.1	-0.4
Lung cancer (father)	0.1	0.1	0.1	-0.3
Headache pain in last month	0.1	0.1	0.1	-0.4
Health satisfaction	0.1	0.1	0.1	-0.3
Neck or shoulder pain in last month	0.1	0.1	0.1	0.4
Medication: Allopurinol	0.1	0.1	0.1	0.3
Medication: Seretide 50 evohaler	0.1	0.1	0.1	0.4
Chest pain or discomfort	0.1	0.1	0.1	0.3
Had major operations	0.1	0.1	0.1	0.3
Leg pain on walking	0.1	0.1	0.1	-0.3
Diabetes diagnosed by doctor	0.1	0.1	0.1	-0.3
Medication: Gliclazide	0.1	0.1	0.1	-0.3
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.1	-0.4
High cholesterol (Self-reported)	0.1	0.2	0.2	0.5
Leg fat percentage (left)	0.1	0.4	0.4	0.6
Schizophrenia (2018)	0.0	0.0	0.0	-0.1
Worry (Nagel 2018)	0.0	0.1	0.1	-0.2
Alzheimer’s Disease (in mother)	0.0	0.1	0.1	0.2
Breast Cancer	0.0	0.1	0.1	-0.2
Ovarian Cancer	0.0	0.1	0.1	-0.2
Prostate Cancer	0.0	0.0	0.0	0.0
HDL Cholesterol	0.0	0.0	0.0	0.2
Schizophrenia (2014)	0.0	0.0	0.0	-0.2
Type 2 Diabetes (T2D) (2012)	0.0	0.0	0.0	0.1
Tanning	0.0	0.5	0.5	0.7
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	-0.1
Supplements: Zinc	0.0	0.0	0.0	-0.1
Medication: Co-codamol	0.0	0.0	0.0	0.2
Hand grip strength (right)	0.0	0.1	0.1	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.0	0.0	0.0	-0.0
Qualifications: CSEs or equivalent	0.0	0.0	0.0	-0.2
Diverticular disease/diverticulitis (self-reported)	0.0	0.0	0.0	0.1
Body mass index (BMI)	0.0	0.0	0.0	-0.2
Trunk fat mass	0.0	0.0	0.0	0.1
Waist circumference	0.0	0.1	0.1	-0.4
Nervous feelings	0.0	0.0	0.0	-0.2
Hair/balding pattern: Pattern 2	0.0	0.0	0.0	0.2
Allergy	0.0	0.0	0.0	-0.2
Pain all over the body in last month	0.0	0.0	0.0	0.2
Hip circumference	0.0	0.0	0.0	0.0
Time employed in main current job	0.0	0.0	0.0	0.2
Alcohol intake versus 10 years previously	0.0	0.0	0.0	0.0
Hair/balding pattern: Pattern 3	0.0	0.0	0.0	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.0	0.0	0.0	0.1
Arm fat mass (right)	0.0	0.0	0.0	-0.1
Length of working week for main job	0.0	0.0	0.0	0.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.0	0.0	0.0	-0.1
Birth weight of first child	0.0	0.1	0.1	0.3
Pulse wave reflection index	0.0	0.0	0.0	0.2
Medication: Paracetamol	0.0	0.1	0.1	-0.3
Medication: Amlodipine	0.0	0.0	0.0	-0.2
Comparative body size at age 10	0.0	0.1	0.1	-0.4
Emphysema/chronic bronchitis	0.0	0.0	0.0	0.1
Heart disease (mother)	0.0	0.0	0.0	-0.1
Whole body fat mass	0.0	0.0	0.0	0.1
Leg fat mass (right)	0.0	0.1	0.1	0.3
Alcohol intake frequency.	0.0	0.0	0.0	-0.2
Comparative height size at age 10	0.0	0.2	0.2	0.4
Age at last live birth	0.0	0.0	0.0	-0.0
Qualifications: NVQ or HND or HNC or equivalent	0.0	0.0	0.0	-0.0
Supplements: Vitamin C	0.0	0.0	0.0	-0.1
Illnesses of siblings: Diabetes	0.0	0.0	0.0	0.2
Average weekly red wine intake	0.0	0.0	0.0	0.1
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.0	0.0
Ever had bowel cancer screening	0.0	0.0	0.0	-0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.0	0.0	0.0	0.2
Back pain experienced in last month	0.0	0.1	0.1	0.2
Osteoarthritis (self-reported)	0.0	0.0	0.0	-0.0
Arm fat mass (left)	0.0	0.0	0.0	0.1
Miserableness	0.0	0.0	0.0	-0.1
Commuting to job workplace: Public transport	0.0	0.0	0.0	-0.2
Eye problems/disorders: Glaucoma	0.0	0.0	0.0	0.1
Medication: Paracetamol	0.0	0.0	0.0	0.2
Illnesses of father: High blood pressure	0.0	0.0	0.0	-0.1
Alcohol drinker status: Never	0.0	0.0	0.0	-0.2
Ever smoked	0.0	0.1	0.1	0.3
Number of operations (self-reported)	0.0	0.0	0.0	-0.1
Irritability	0.0	0.0	0.0	-0.2
Leg fat mass (left)	0.0	0.1	0.1	0.2

Hub : Genes

ESR1

Models

Trait associations