TWAS hub - CCDC170

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	METSIM	Adipose	0.144	0.0336	7.0e-09	0.016	0.072	0.057	0.064	0.031	1.4e-03	6.1e-11	6.8e-09	8.1e-10	1.5e-05
2	ROSMAP	Brain Pre-frontal Cortex	0.199	0.0344	9.4e-14	0.056	0.164	0.179	0.189	0.190	9.0e-08	1.5e-20	1.7e-22	1.1e-23	7.2e-24

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Heel T-Score	43.2	343.9	497.3	-22.3	-13.8
Heel bone mineral density (BMD) T-score, automated (left)	29.3	66.4	96.2	-9.8	-6.0
Heel bone mineral density (BMD) T-score, automated (right)	24.8	56.8	86.9	-9.3	-5.2
Fractured/broken bones in last 5 years	8.4	10.9	13.2	3.6	2.9
Ever depressed for a whole week	8.1	10.0	14.1	-3.7	-2.4
Ever unenthusiastic/disinterested for a whole week	4.4	5.4	9.8	-3.1	-1.0
Number of live births	4.4	6.2	9.6	-3.1	-1.7
Pain experienced in last month	4.2	7.1	13.0	3.6	1.1
Bilateral oophorectomy (both ovaries removed)	4.1	4.8	8.0	-1.2	-2.8
Breast Cancer	4.0	9.5	11.9	-3.5	-2.7
Mean Putamen Volume	4.0	4.6	4.8	-2.2	-2.1
Worry (Nagel 2018)	3.0	6.3	12.5	-3.5	-0.4
Illnesses of father: High blood pressure	3.0	3.8	7.2	-2.7	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	2.9	3.9	5.9	-1.4	-2.4
Headache pain in last month	2.8	4.9	9.7	-3.1	0.1
Qualifications: CSEs or equivalent	2.7	3.5	6.7	0.7	2.6
Health satisfaction	2.7	3.5	6.5	-2.5	-0.7
Supplements: Vitamin C	2.7	3.2	4.2	2.0	-1.5
Breast cancer (self-reported)	2.6	3.1	6.2	2.5	0.0
Frequency of depressed mood in last 2 weeks	2.5	3.5	3.6	-1.8	-1.9
Diabetes (father)	2.5	3.1	5.6	-2.4	0.8
Osteoporosis (self-reported)	2.5	3.1	6.2	2.5	-0.1
Depression (Nagel 2018)	2.3	3.5	4.9	-1.5	-2.2
Number of incorrect matches in round	2.1	3.5	6.1	-1.0	-2.5
Age when periods started (menarche)	2.0	4.8	4.8	2.2	2.2
Chronic bronchitis/emphysema (father)	2.0	2.3	2.3	1.5	1.5
Eye problems/disorders: Cataract	2.0	2.3	2.4	-1.5	-1.5
Age at First Birth	1.9	2.7	3.2	1.8	1.5
Diabetes (mother)	1.9	2.4	4.9	-2.2	0.0
Number of full brothers	1.9	2.3	4.4	0.5	2.1
Illnesses of father: None of the above (group 1)	1.9	2.3	3.8	0.9	-2.0
Maternal smoking around birth	1.8	2.5	3.2	1.8	1.4
Knee pain experienced in last month	1.8	2.8	4.7	-2.2	0.9
Rheumatoid Arthritis	1.7	2.3	2.5	1.6	1.5
Alzheimer’s Disease (in mother)	1.6	1.9	2.3	-1.2	-1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.4	4.8	-2.2	-0.2
Loud music exposure frequency	1.6	1.8	3.5	1.9	0.2
LDL Cholesterol	1.5	2.3	2.7	1.6	1.4
Mouth/teeth dental problems: Bleeding gums	1.5	1.9	2.3	-1.5	-1.2
Glaucoma (self-reported)	1.5	1.8	2.2	1.5	1.2
Commuting to job workplace: Car/motor vehicle	1.5	1.8	2.0	1.2	1.4
Ovarian Cancer	1.4	1.9	3.7	-1.9	0.2
Blood Red Count	1.4	13.2	24.9	5.0	1.3
Qualifications: O levels/GCSEs or equivalent	1.4	2.2	3.6	-1.9	-0.9
Illness, injury, bereavement, stress in last 2 years	1.4	1.7	2.4	-1.5	-1.0
Illnesses of father: Heart disease	1.4	2.0	4.0	-0.2	2.0
Supplements: Calcium	1.4	1.6	3.0	1.7	-0.3
Neuroticism (Nagel 2018)	1.3	3.2	5.8	-2.4	-0.8
Schizophrenia (2018)	1.3	2.7	5.2	-0.6	-2.3
Hypothyroidism (self reported)	1.3	3.1	4.9	2.2	1.1
Birth weight of first child	1.3	2.4	4.5	-0.6	-2.1
Alcohol intake frequency.	1.3	2.9	3.9	-2.0	-1.4
Suffer from ‘nerves’	1.3	2.0	4.0	-2.0	0.1
Average weekly red wine intake	1.3	1.9	3.8	1.9	-0.2
Loneliness, isolation	1.3	1.8	2.4	-1.1	-1.5
Long-standing illness, disability or infirmity	1.3	1.9	3.6	-1.9	-0.5
Basal cell carcinoma (self-reported)	1.3	1.6	2.5	-1.6	0.8
Schizophrenia (2014)	1.2	2.6	5.0	0.4	-2.2
Length of working week for main job	1.2	1.3	1.8	0.9	1.4
Had major operations	1.2	1.5	2.4	-0.7	-1.5
Eye problems/disorders: Glaucoma	1.2	1.4	1.6	1.3	1.0
Blood Eosinophil Count	1.1	8.6	12.0	2.3	3.5
Vitamin and mineral supplements	1.1	1.5	1.5	-1.2	1.2
Relative age voice broke	1.1	1.6	2.1	-1.4	-1.1
Financial difficulties in last 2 years	1.1	1.5	1.9	1.4	1.0
Worrier / anxious feelings	1.1	2.1	4.0	-2.0	0.4
Lung cancer (father)	1.1	1.3	2.6	-0.0	-1.6
HDL Cholesterol	1.0	1.6	1.9	-1.4	-1.1
Neuroticism	1.0	2.4	4.3	-2.1	-0.7
Hand grip strength (left)	1.0	2.6	2.9	-1.7	-1.5
Leg fat-free mass (left)	1.0	5.4	8.1	-1.6	-2.9
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	1.8	1.3	0.7
Leg predicted mass (left)	1.0	5.2	7.7	-1.6	-2.8
Father’s age at death	1.0	1.3	2.5	0.2	1.6
Medication: Omeprazole	1.0	1.2	2.1	-0.5	-1.5
Mean time to correctly identify matches	1.0	2.0	4.0	-0.1	-2.0
Heart disease (mother)	1.0	1.2	2.4	1.5	-0.3
Leg fat-free mass (right)	1.0	5.3	8.1	-1.6	-2.8
Leg predicted mass (right)	1.0	5.3	8.0	-1.6	-2.8
Supplements: Fish oil (including cod liver oil)	1.0	1.3	1.4	-1.2	-1.1
Medication: Paracetamol	1.0	1.6	2.1	1.0	1.4
Deep venous thrombosis (DVT) (self-reported)	1.0	1.3	2.6	-1.6	0.2
Depressed Affect (Nagel 2018)	0.9	1.9	2.7	-1.6	-1.1
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	2.1	0.4	-1.4
Medication: Levothyroxine sodium	0.9	1.6	2.0	1.4	1.1
Fluid intelligence score	0.9	1.8	1.8	1.3	1.4
Hair/balding pattern: Pattern 3	0.9	1.3	2.5	0.3	-1.6
Noisy workplace	0.9	1.1	1.8	0.7	1.3
Leg pain on walking	0.9	1.1	2.2	-1.5	0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	2.9	-1.7	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.9	1.4	2.9	-1.7	-0.1
Bipolar Disorder or Schizophrenia	0.8	2.0	3.3	-0.8	-1.8
Reaction Time	0.8	1.6	3.0	-0.3	-1.7
Medication: Metformin	0.8	1.2	1.4	1.0	1.2
Medication: Ramipril	0.8	1.1	2.0	0.3	1.4
Medication: Ibuprofen (e.g. Nurofen)	0.8	1.0	1.0	-0.9	1.0
Medication: Paracetamol	0.8	1.4	2.3	0.7	1.5
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	2.9	1.7	0.5
Pulse wave peak to peak time	0.8	1.0	1.9	-1.4	-0.3
Pulse rate, automated reading	0.8	2.5	3.2	1.8	-1.4
Commuting to job workplace: Walk	0.8	0.9	1.8	0.1	-1.3
Back pain experienced in last month	0.8	1.2	1.5	-1.2	-0.9
Basal metabolic rate	0.8	4.4	5.7	-1.7	-2.4
Ulcerative Colitis (UC)	0.7	1.4	2.0	1.4	0.9
Relative age of first facial hair	0.7	1.4	2.8	-1.7	0.3
Ever had hysterectomy (womb removed)	0.7	0.8	1.1	-1.1	-0.7
Medication: Co-codamol	0.7	0.9	1.5	-0.5	1.2
Taking other prescription medications	0.7	1.0	1.3	0.8	1.1
Sitting height	0.7	5.2	5.4	-2.2	-2.3
Hair/balding pattern: Pattern 2	0.7	0.9	1.4	-0.5	1.2
Neuroticism score	0.7	1.4	2.8	-1.7	-0.3
Hip circumference	0.7	2.9	3.0	-1.7	-1.7
Falls in the last year	0.7	0.9	1.4	1.2	0.7
Blood clot in the leg (DVT)	0.7	0.9	1.3	-1.1	0.7
Chronic bronchitis/emphysema (mother)	0.7	0.8	1.6	1.3	-0.3
Whole body fat-free mass	0.7	4.0	5.2	-1.6	-2.3
Number of self-reported non-cancer illnesses	0.7	1.2	2.2	0.5	1.5
Wears glasses or contact lenses	0.7	0.8	1.5	1.2	0.2
Financial situation satisfaction	0.7	0.9	1.4	1.2	0.6
Major Depression (MDD)	0.6	0.7	1.2	-1.1	0.4
HbA1C	0.6	0.7	1.1	0.6	1.0
Ulcerative Colitis	0.6	0.9	1.5	1.2	0.6
Lung FEV1/FVC ratio	0.6	3.3	5.3	-1.1	-2.3
Hand grip strength (right)	0.6	1.7	3.3	-1.8	-0.3
Hayfever, allergic rhinitis or eczema	0.6	1.3	1.3	1.2	1.1
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.3	-1.2	-0.2
Impedance of leg (left)	0.6	2.9	4.9	0.9	2.2
Weight	0.6	2.9	3.6	-1.5	-1.9
Trunk fat-free mass	0.6	3.3	3.8	-1.7	-1.9
Frequency of tiredness / lethargy in last 2 weeks	0.6	1.0	1.8	-1.3	-0.4
Forced expiratory volume in 1-second (FEV1)	0.6	2.1	3.2	-1.0	-1.8
Arm fat mass (right)	0.6	2.3	3.5	-1.1	-1.9
Trunk predicted mass	0.6	3.5	4.0	-1.7	-2.0
Reason for reducing amount of alcohol drunk: Health precaution	0.6	0.7	0.9	-0.8	-0.9
Age at first live birth	0.6	1.0	1.9	1.4	0.4
Neck or shoulder pain in last month	0.6	0.9	1.2	-1.1	0.7
Smoking status: Previous	0.6	1.0	1.2	0.9	1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.3	-1.1	0.1
Whole body water mass	0.6	3.6	4.9	-1.5	-2.2
Hearing aid user	0.6	0.7	1.0	0.7	1.0
Mother’s age at death	0.6	0.8	1.1	-0.7	-1.1
Commuting to job workplace: Public transport	0.6	0.8	1.0	-1.0	-0.7
Average weekly beer plus cider intake	0.6	0.9	1.3	-1.1	0.8
Irritable Bowel Disease (IBD)	0.5	1.2	1.7	0.8	1.3
Bipolar Disorder (2011)	0.5	0.5	0.6	0.8	-0.7
Fasting Glucose	0.5	0.6	1.3	1.1	0.2
Type 2 Diabetes (T2D) (2012)	0.5	0.6	0.8	-0.9	0.5
Blood White Count	0.5	4.1	7.1	2.7	1.0
Systolic blood pressure, automated reading	0.5	1.6	2.6	1.6	0.7
Pack years adult smoking proportion	0.5	0.7	1.0	-1.0	-0.7
Impedance of leg (right)	0.5	2.5	4.3	0.9	2.1
Townsend deprivation index at recruitment	0.5	0.7	1.3	1.1	-0.0
Serious illness, injury or assault to yourself	0.5	0.6	0.7	0.7	0.8
Nervous feelings	0.5	0.9	0.9	-0.9	1.0
Mouth/teeth dental problems	0.5	0.8	1.5	1.2	0.1
Prospective memory result	0.5	0.6	1.0	-0.3	-1.0
Pulse wave Arterial Stiffness index	0.5	0.6	1.2	1.1	-0.1
Peak expiratory flow (PEF)	0.5	1.1	2.0	-0.3	-1.4
Exposure to tobacco smoke outside home	0.5	0.7	0.8	0.9	-0.8
Shortness of breath walking on level ground	0.5	0.6	1.2	-0.1	1.1
Migraine (self-reported)	0.5	0.6	1.0	-0.4	1.0
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	0.8	0.9	-0.6
Medication: Aspirin	0.5	0.6	1.0	1.0	-0.6
Arm fat mass (left)	0.5	2.1	3.0	-1.1	-1.7
Medication: Lisinopril	0.5	0.7	1.3	-0.3	-1.1
Risk taking	0.5	0.7	0.9	0.7	0.9
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.2	0.0	-1.1
Alcohol drinker status: Previous	0.5	0.6	0.8	-0.7	-0.9
Pack years of smoking	0.5	0.7	1.0	-1.0	-0.6
Alzheimer’s Disease (in father)	0.4	0.4	0.5	0.7	-0.5
Alzheimer’s Disease (including proxy)	0.4	0.5	0.9	-0.4	-0.9
Height	0.4	8.3	11.0	-2.4	-3.3
Cardiovascular Disease	0.4	1.4	2.0	-1.4	0.9
Multivitamins +/- minerals	0.4	0.5	1.0	0.1	-1.0
Happiness	0.4	0.4	0.8	0.3	-0.9
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.5	0.9	0.2	-1.0
Medication: Cholesterol lowering	0.4	0.7	1.0	1.0	0.5
Standing height	0.4	4.1	5.1	-1.8	-2.3
Tense / ‘highly strung’	0.4	0.7	1.4	-1.2	-0.2
Arm fat-free mass (right)	0.4	2.1	2.1	-1.5	-1.4
Mouth/teeth dental problems: Loose teeth	0.4	0.4	0.8	-0.2	-0.9
Medication: Allopurinol	0.4	0.5	0.8	0.5	0.9
Age at last live birth	0.4	0.5	1.0	1.0	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	0.7	-0.4	-0.9
Mood swings	0.4	0.7	1.2	-1.1	0.4
Average weekly champagne plus white wine intake	0.4	0.5	0.6	0.8	-0.6
Medication: Bendroflumethiazide	0.4	0.6	1.0	1.0	0.5
Alcohol drinker status: Never	0.4	0.5	1.0	1.0	0.2
Ever smoked	0.4	0.7	1.3	-1.1	-0.2
Arm fat-free mass (left)	0.4	2.0	2.0	-1.4	-1.4
Heart attack/myocardial infarction (self-reported)	0.4	0.5	0.8	0.9	-0.4
Arm predicted mass (left)	0.4	1.9	2.3	-1.5	-1.2
Schizophrenia vs Biploar Disorder	0.3	0.4	0.7	0.4	-0.8
Body Mass Index (BMI) (2010)	0.3	0.5	0.9	0.0	1.0
Primary Biliary Cirrhosis	0.3	0.4	0.7	-0.8	-0.3
Chronotype (morning person)	0.3	0.7	1.3	-1.1	-0.2
Average weekly spirits intake	0.3	0.4	0.6	0.8	0.5
Hearing difficulty/problems: Yes	0.3	0.4	0.8	0.1	0.9
Medication for hormone replacement therapy	0.3	0.3	0.4	-0.4	-0.6
High blood pressure	0.3	0.7	1.3	0.4	1.1
Supplements: Glucosamine	0.3	0.4	0.5	-0.6	-0.7
Waist circumference	0.3	1.0	1.3	-0.8	-1.1
Alcohol usually taken with meals	0.3	0.5	0.5	0.7	-0.7
Forced vital capacity (FVC)	0.3	1.3	1.6	-1.0	-1.3
Heart attack	0.3	0.4	0.7	0.8	-0.3
Pain all over the body in last month	0.3	0.3	0.6	-0.7	-0.2
Medication: Simvastatin	0.3	0.4	0.7	0.9	0.4
Arm fat percentage (right)	0.3	1.2	1.8	-0.8	-1.3
Asthma	0.3	0.5	1.0	-1.0	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.3	1.1	2.0	-0.3	-1.4
Breastfed as a baby	0.3	0.4	0.5	-0.7	0.5
Pulse wave reflection index	0.3	0.4	0.8	0.9	-0.2
Ever highly irritable/argumentative for 2 days	0.3	0.4	0.8	-0.9	0.1
Gout (self-reported)	0.3	0.4	0.7	0.3	0.8
Worry too long after embarrassment	0.3	0.4	0.8	-0.3	0.9
Eye problems/disorders: None of the above	0.3	0.3	0.6	0.2	0.8
Emphysema/chronic bronchitis	0.3	0.3	0.4	0.6	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.4	0.6	-0.8	-0.4
Arm predicted mass (right)	0.3	1.6	1.7	-1.2	-1.3
Family relationship satisfaction	0.3	0.3	0.6	-0.1	0.8
Medication: Aspirin	0.3	0.4	0.6	0.8	-0.5
Arm fat percentage (left)	0.3	1.3	2.2	-0.6	-1.5
Qualifications: nursing, teaching	0.3	0.4	0.7	0.4	-0.8
Mineral and other dietary supplements	0.3	0.4	0.9	0.1	0.9
Asthma (self-reported)	0.3	0.7	1.3	-1.2	0.0
Osteoarthritis (self-reported)	0.3	0.4	0.4	-0.6	0.6
Guilty feelings	0.3	0.4	0.8	0.9	-0.3
Medication: Atorvastatin	0.3	0.3	0.5	-0.7	-0.4
Heart disease (siblings)	0.3	0.3	0.4	-0.6	-0.5
Verbal and Numeric Reasoning (VNR)	0.2	0.5	0.5	0.7	0.7
Crohns Disease (2012)	0.2	0.3	0.5	0.7	0.4
Systolic Blood Pressure	0.2	1.0	1.9	1.4	0.2
Smoking Status	0.2	0.5	0.6	0.7	0.7
Allergy or Eczema	0.2	0.4	0.5	0.7	0.6
Type 2 Diabetes (T2D) (2018)	0.2	0.4	0.5	0.5	0.7
Ever used hormone-replacement therapy (HRT)	0.2	0.2	0.2	-0.4	-0.5
Fed-up feelings	0.2	0.3	0.4	-0.5	0.6
Stomach or abdominal pain in last month	0.2	0.3	0.3	-0.6	-0.5
Body mass index (BMI)	0.2	0.7	0.9	-0.6	-1.0
Trunk fat mass	0.2	0.9	1.7	-0.4	-1.3
Past tobacco smoking	0.2	0.3	0.3	-0.6	-0.6
Had other major operations	0.2	0.2	0.4	-0.2	0.6
Qualifications: None of the above	0.2	0.4	0.6	-0.3	0.8
Allergy	0.2	0.4	0.8	0.1	-0.9
Hayfever/allergic rhinitis (self-reported)	0.2	0.2	0.5	0.0	0.7
Qualifications: A levels/AS levels or equivalent	0.2	0.5	0.7	-0.5	-0.8
Medication: Amlodipine	0.2	0.2	0.3	-0.6	-0.4
Number of children fathered	0.2	0.2	0.4	-0.7	-0.1
Medication: Blood pressure	0.2	0.4	0.5	0.5	0.7
Medication: Ibuprofen	0.2	0.3	0.5	-0.3	0.7
Whole body fat mass	0.2	1.0	1.8	-0.5	-1.3
Leg fat mass (right)	0.2	0.6	1.1	-0.3	-1.1
Comparative height size at age 10	0.2	1.0	1.7	-0.4	-1.3
Number of full sisters	0.2	0.2	0.5	-0.0	0.7
Overall health rating	0.2	0.4	0.6	-0.4	0.7
Hypertension (Self-reported)	0.2	0.5	0.9	0.4	0.9
Ever had bowel cancer screening	0.2	0.3	0.3	0.5	0.5
Friendships satisfaction	0.2	0.3	0.6	-0.1	0.8
Ever taken oral contraceptive pill	0.2	0.2	0.3	-0.6	0.2
Pain type(s) experienced in last month: Hip pain	0.2	0.2	0.4	0.6	0.2
Number of operations (self-reported)	0.2	0.3	0.5	-0.7	0.1
Myopia	0.2	0.3	0.5	0.7	0.3
Bipolar Disorder (2018)	0.1	0.1	0.3	-0.5	-0.1
Intelligence (Savage-Jansen 2018)	0.1	0.2	0.3	-0.6	-0.2
Crohns Disease (2017)	0.1	0.2	0.3	-0.2	0.6
Lupus	0.1	0.1	0.2	-0.2	0.4
Triglycerides	0.1	0.1	0.2	0.4	-0.2
BMI	0.1	0.5	0.9	-0.9	-0.5
Waist Hip Ratio (WHR)	0.1	0.6	1.0	1.0	0.5
Respiratory disease	0.1	0.2	0.3	-0.6	-0.1
Lung FVC	0.1	0.4	0.8	-0.2	-0.9
Number of treatments/medications taken	0.1	0.1	0.2	-0.2	-0.4
Sensitivity / hurt feelings	0.1	0.2	0.3	-0.5	0.4
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.1	-0.2	-0.3
Angina	0.1	0.1	0.2	-0.5	-0.1
Supplements: Zinc	0.1	0.1	0.2	0.4	0.3
Severe depression (siblings)	0.1	0.1	0.1	0.3	0.2
Trunk fat percentage	0.1	0.4	0.7	0.2	-0.8
Medication: Atenolol	0.1	0.1	0.2	0.5	0.2
High blood pressure (mother)	0.1	0.2	0.2	-0.5	-0.4
Hearing difficulty/problems with background noise	0.1	0.2	0.5	-0.2	0.7
Diabetes (self-reported)	0.1	0.2	0.4	0.6	0.1
Alcohol intake versus 10 years previously	0.1	0.1	0.1	-0.3	0.2
Pulse rate	0.1	0.1	0.2	-0.4	-0.2
Mouth/teeth dental problems: Dentures	0.1	0.2	0.3	0.3	0.5
Depression (self-reported)	0.1	0.1	0.1	-0.2	-0.3
Medication: Lansoprazole	0.1	0.1	0.2	-0.0	0.5
Illnesses of mother	0.1	0.1	0.2	-0.3	0.4
Exposure to tobacco smoke at home	0.1	0.1	0.2	0.1	-0.5
Hair/balding pattern: Pattern 4	0.1	0.1	0.1	-0.4	0.3
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.3	0.0	-0.6
Birth weight	0.1	0.2	0.4	-0.3	-0.6
High blood pressure (siblings)	0.1	0.2	0.3	-0.6	0.3
Body fat percentage	0.1	0.3	0.5	0.1	-0.7
Comparative body size at age 10	0.1	0.4	0.7	0.9	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.1	-0.4	-0.0
Qualifications: College or University degree	0.1	0.2	0.2	0.4	-0.4
Diabetes diagnosed by doctor	0.1	0.1	0.2	0.0	0.5
Medication for cholesterol	0.1	0.2	0.4	0.2	0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.2	-0.4	0.1
Miserableness	0.1	0.2	0.3	-0.5	0.3
Tinnitus: Yes, now most or all of the time	0.1	0.2	0.3	0.5	0.2
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	-0.3	0.3
Unable to work because of sickness or disability	0.1	0.1	0.2	-0.5	-0.2
Commuting to job workplace: Cycle	0.1	0.1	0.2	0.4	-0.3
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.7	0.0	-0.8
Impedance of whole body	0.1	0.6	0.9	0.5	1.0
Leg fat mass (left)	0.1	0.5	0.8	-0.3	-0.9
Prostate Cancer	0.0	0.0	0.0	0.0	0.0
Coronary Artery Disease (CAD)	0.0	0.1	0.1	-0.3	-0.0
Neuroticism (2016)	0.0	0.0	0.0	-0.1	0.2
Blood Platelet Count	0.0	0.5	0.5	0.7	0.7
Hair Pigment	0.0	0.6	1.2	-0.1	-1.1
Tanning	0.0	0.6	1.0	-0.4	1.0
Current tobacco smoking	0.0	0.0	0.1	0.3	-0.0
Average weekly fortified wine intake	0.0	0.0	0.0	0.1	-0.2
Frequency of tenseness / restlessness in last 2 weeks	0.0	0.0	0.1	-0.3	0.0
Had menopause	0.0	0.0	0.0	-0.1	0.1
Illnesses of siblings	0.0	0.0	0.0	0.1	-0.0
Impedance of arm (right)	0.0	0.1	0.1	0.1	-0.3
Time employed in main current job	0.0	0.0	0.0	-0.1	-0.1
Impedance of arm (left)	0.0	0.2	0.4	-0.0	-0.7
Medication for cholesterol, blood pressure or diabetes	0.0	0.0	0.0	-0.2	0.2
Forced vital capacity (FVC), Best measure	0.0	0.1	0.2	0.2	-0.5
Leg fat percentage (right)	0.0	0.0	0.1	0.3	0.0
Wheeze or whistling in the chest in last year	0.0	0.1	0.1	-0.0	-0.4
Medication for pain relief, constipation, heartburn	0.0	0.1	0.1	0.1	-0.3
Angina (self-reported)	0.0	0.0	0.1	-0.3	-0.1
Medication: Seretide 50 evohaler	0.0	0.0	0.0	0.2	0.0
Chest pain or discomfort	0.0	0.0	0.1	0.3	-0.1
Illnesses of siblings: Diabetes	0.0	0.0	0.1	-0.2	-0.3
Handedness (chirality/laterality): Left-handed	0.0	0.0	0.0	-0.1	-0.2
Medication: Gliclazide	0.0	0.0	0.0	0.2	-0.2
Smoking status: Current	0.0	0.0	0.0	0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.0	0.0	0.1	-0.3	-0.0
Medication: Blood pressure	0.0	0.1	0.1	0.2	-0.3
High cholesterol (Self-reported)	0.0	0.1	0.1	0.3	0.1
Leg fat percentage (left)	0.0	0.0	0.0	0.2	0.1
Irritability	0.0	0.0	0.1	-0.0	0.2
Age started oral contraceptive pill	0.0	0.0	0.0	-0.0	-0.1
Diastolic blood pressure, automated reading	0.0	0.0	0.0	0.1	0.2
Cholesterol lowering medication	0.0	0.1	0.1	-0.3	-0.1

Hub : Genes

CCDC170

Models

Trait associations