[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ← →

chr11:59,239,839-62,326,265

Best TWAS P=1.09e-08 · Best GWAS P=2.51e-09 conditioned to 0.369

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Stomach Adenocarcinoma	MS4A2	0.04	0.04	blup	55	0.04	8.2e-04	-5.1	-5.7	1.1e-08	-0.79	0.02	0.93	TRUE
9	The Cancer Genome Atlas	Glioblastoma Multiforme	MS4A14	0.44	0.38	blup	86	0.42	3.6e-14	3.8	-5.4	5.8e-08	-0.19	0.03	0.97	TRUE
2	GTEx	Colon Transverse	FADS2	0.18	0.11	lasso	7	0.16	8.1e-08	4.4	5.4	6.1e-08	-0.01	0.01	0.97	TRUE
7	YFS	Blood	MS4A6A	0.13	0.10	enet	33	0.11	2.5e-35	-5.1	5.6	1.9e-08	0.52	0.28	0.72	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	MS4A4A	0.04	0.03	blup	79	0.04	7.2e-08	5.4	5.6	2.1e-08	0.80	0.03	0.97	FALSE
11	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	MS4A6A	0.05	0.01	enet	10	0.03	6.6e-03	5.4	5.6	2.5e-08	0.85	0.01	0.63	FALSE
1	GTEx	Artery Aorta	MS4A7	0.15	0.02	enet	28	0.04	3.6e-03	4.1	-5.6	2.6e-08	-0.18	0.64	0.12	FALSE
4	GTEx	Whole Blood	MS4A6A	0.05	0.03	lasso	5	0.03	6.1e-04	-5.2	5.4	5.5e-08	0.70	0.19	0.76	FALSE
3	GTEx	Nerve Tibial	MS4A14	0.26	0.25	lasso	7	0.24	1.2e-16	4.8	-5.4	6.4e-08	-0.17	0.68	0.32	FALSE
10	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MS4A7	0.02	0.00	blup	77	0.00	1.2e-01	-3.5	5.3	1.0e-07	0.39	0.04	0.48	FALSE
6	YFS	Blood	FADS1	0.11	0.08	lasso	8	0.09	6.1e-29	4.4	5.3	1.2e-07	-0.01	0.01	0.96	FALSE
5	GTEx	Whole Blood	MS4A14	0.08	0.01	lasso	4	0.02	2.9e-03	3.8	-5.3	1.3e-07	-0.19	0.44	0.18	FALSE
13	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MS4A4A	0.16	0.02	blup	78	0.03	2.7e-02	5.4	5.2	2.2e-07	0.77	0.01	0.62	FALSE