Best TWAS P=1.37e-12 · Best GWAS P=2.5e-13 conditioned to 0.00411
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | HHIP-AS1 | 0.12 | 0.02 | enet | 16 | 0.04 | 0.04590 | -2.5 | -5.2 | 1.6e-07 | 0.37 | 0.06 | 0.23 | TRUE |
| 2 | GTEx | Vagina | HHIP-AS1 | 0.16 | 0.10 | lasso | 7 | 0.06 | 0.01760 | -5.3 | -6.4 | 1.7e-10 | 0.79 | 0.03 | 0.75 | FALSE |
| 3 | NTR | Blood | MMAA | 0.04 | 0.00 | bslmm | 343 | 0.01 | 0.00011 | 3.3 | -7.1 | 1.4e-12 | 0.42 | 0.09 | 0.32 | TRUE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | OTUD4 | 0.15 | 0.06 | blup | 31 | 0.05 | 0.00825 | -5.1 | 5.7 | 9.5e-09 | -0.80 | 0.01 | 0.45 | FALSE |