TWAS hub - MMAA

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1500	0.0330	8.9e-10	0.126	0.066	0.126	0.124	0.128	4.5e-15	1.8e-08	4.6e-15	6.6e-15	2.8e-15
2	GTEx	Artery Tibial	0.1448	0.0448	3.4e-04	0.021	NA	0.081	NA	0.049	8.6e-03	NA	6.2e-07	NA	9.4e-05
3	GTEx	Cells Transformed fibroblasts	0.1520	0.0440	2.0e-04	0.137	NA	0.142	NA	0.140	1.9e-10	NA	8.8e-11	NA	1.3e-10
4	GTEx	Colon Sigmoid	0.2390	0.0920	8.3e-03	0.127	NA	0.028	NA	0.080	3.0e-05	NA	3.6e-02	NA	9.0e-04
5	GTEx	Heart Left Ventricle	0.2099	0.0653	9.0e-04	0.132	NA	0.092	NA	0.095	1.7e-07	NA	1.4e-05	NA	9.5e-06
6	GTEx	Muscle Skeletal	0.1558	0.0416	4.1e-05	0.124	NA	0.113	NA	0.112	3.5e-12	NA	3.2e-11	NA	4.6e-11
7	NTR	Blood	0.0378	0.0133	3.4e-04	0.003	0.008	0.002	0.011	0.003	2.2e-02	7.6e-04	4.4e-02	1.1e-04	2.7e-02
8	ROSMAP	Brain Pre-frontal Cortex	0.1348	0.0319	3.8e-08	0.120	0.074	0.104	0.105	0.106	3.8e-15	8.3e-10	2.6e-13	2.1e-13	1.7e-13
9	TCGA	Breast Invasive Carcinoma	0.0352	0.0176	3.6e-03	0.017	0.010	0.009	NA	0.013	1.4e-04	3.5e-03	4.2e-03	NA	9.8e-04
10	TCGA	Cervical Squamous Cell Carcinoma	0.1210	0.0530	2.2e-04	0.067	0.050	0.058	NA	0.108	3.3e-04	1.8e-03	7.8e-04	NA	5.8e-06
11	TCGA	Colon Adenocarcinoma	0.1120	0.0520	3.2e-03	0.065	0.034	0.020	NA	0.054	1.3e-04	4.8e-03	2.4e-02	NA	4.5e-04
12	TCGA	Glioblastoma Multiforme	0.2120	0.1310	5.6e-03	0.049	0.079	0.104	NA	0.059	1.3e-02	2.1e-03	4.8e-04	NA	7.2e-03
13	TCGA	Head and Neck Squamous Cell Carcinoma	0.0486	0.0281	3.2e-03	0.048	0.029	0.035	NA	0.045	3.7e-06	2.7e-04	6.7e-05	NA	8.3e-06
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.1649	0.0552	9.3e-09	0.060	0.096	0.100	NA	0.077	2.6e-07	6.3e-11	2.3e-11	NA	5.4e-09
15	TCGA	Brain Lower Grade Glioma	0.0758	0.0276	5.3e-07	0.084	0.056	0.080	NA	0.083	8.8e-10	5.5e-07	2.4e-09	NA	1.1e-09
16	TCGA	Lung Adenocarcinoma	0.1116	0.0364	2.6e-09	0.097	0.086	0.084	NA	0.091	2.1e-11	3.2e-10	4.3e-10	NA	8.8e-11
17	TCGA	Lung Squamous Cell Carcinoma	0.0714	0.0296	2.9e-06	0.056	0.044	0.046	NA	0.053	5.0e-07	8.8e-06	5.6e-06	NA	1.1e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Supplements: Calcium	5.6	6.2	14.1	2.6	2.1	2.6	1.6	2.4	1.9	3.8	2.7	2.6	2.6	2.6	1.1	2.6	2.4	2.6	2.6	2.6
Medication: Gliclazide	5.4	6.1	12.0	2.5	1.1	2.2	2.3	2.6	3.5	1.6	3.0	1.9	3.5	2.7	2.4	2.7	-0.2	2.7	2.3	2.8
Heel bone mineral density (BMD) T-score, automated (right)	5.1	11.6	50.3	-3.5	-3.5	-3.3	-0.5	-3.4	-1.7	-7.1	-3.2	-3.1	-2.0	-3.2	-1.3	-3.3	-3.9	-3.3	-3.5	-3.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	4.8	5.8	8.5	2.9	1.0	2.3	2.9	2.6	2.7	0.7	2.9	2.3	2.4	2.7	1.4	2.8	0.8	2.8	2.7	2.8
Number of children fathered	4.5	5.1	9.5	-2.2	-0.9	-2.8	-0.1	-2.1	-2.7	-1.8	-2.3	-3.1	-2.5	-2.6	-1.0	-2.4	-1.9	-2.5	-3.0	-2.4
Lung cancer (father)	4.2	4.9	15.0	-2.1	-1.5	-2.3	-0.2	-2.4	-1.9	-3.9	-2.1	-2.2	-1.5	-2.6	0.2	-2.2	-2.7	-2.2	-2.5	-2.2
Hearing aid user	3.9	4.4	7.7	2.2	1.8	1.9	2.8	2.0	1.6	1.8	2.3	2.1	2.3	2.2	1.2	2.1	2.3	2.2	2.3	2.1
Heart disease (siblings)	3.4	4.2	6.5	2.5	1.6	2.3	0.9	2.0	2.5	0.2	2.4	2.0	2.2	2.5	1.3	2.4	0.9	2.4	2.2	2.5
Serious illness, injury or assault to yourself	3.2	3.9	14.4	-1.9	-0.7	-1.8	1.3	-2.1	-1.2	-3.8	-2.1	-1.8	-1.2	-2.2	0.8	-2.0	-2.2	-2.0	-2.2	-2.2
Reason for reducing amount of alcohol drunk: Health precaution	3.0	3.5	5.4	-2.3	-1.9	-1.7	-1.7	-2.2	-1.2	-1.7	-2.2	-1.7	-1.0	-2.0	-0.4	-2.0	-2.3	-2.0	-2.0	-2.2
Worry too long after embarrassment	2.9	4.8	8.5	-2.5	-1.3	-2.2	-1.8	-2.9	-2.1	-2.1	-2.7	-1.9	-2.7	-2.4	-1.2	-2.5	-0.3	-2.5	-2.2	-2.6
Nervous feelings	2.8	5.2	9.8	2.2	2.6	2.3	2.2	2.1	1.2	3.1	2.3	2.5	2.2	2.2	2.0	2.2	2.2	2.2	2.4	2.2
Heel bone mineral density (BMD) T-score, automated (left)	2.7	6.2	39.7	-2.3	-2.8	-2.1	0.5	-2.5	-0.9	-6.3	-2.3	-1.8	-1.0	-2.1	-0.4	-2.3	-2.2	-2.3	-2.2	-2.4
Medication: Aspirin	2.4	3.1	7.1	2.1	0.5	1.8	1.5	1.6	2.3	-0.5	2.0	1.4	2.4	1.6	2.7	2.0	0.5	1.9	1.4	2.0
Neuroticism (2016)	2.3	3.3	5.1	1.9	1.1	2.1	0.4	1.9	0.9	1.0	2.0	2.2	2.2	2.2	1.8	2.2	0.8	2.2	2.3	2.1
Father’s age at death	2.3	3.0	4.9	-1.7	-2.2	-1.8	-1.3	-1.8	-1.6	-1.3	-1.8	-1.8	-2.0	-2.0	-1.6	-1.8	-0.7	-1.8	-1.8	-1.9
Medication: Lisinopril	2.0	2.5	4.4	-2.0	-0.5	-1.5	-1.0	-2.1	-1.7	-0.9	-1.8	-1.6	-2.0	-1.9	-0.6	-1.9	-0.4	-1.9	-1.8	-1.8
Commuting to job workplace: Car/motor vehicle	1.9	2.2	4.4	1.1	0.7	1.8	1.4	1.3	2.0	0.1	1.4	1.8	2.1	1.6	1.9	1.3	0.7	1.3	1.4	1.5
Ever had bowel cancer screening	1.9	2.2	4.1	-1.8	-0.4	-1.4	0.2	-1.8	-2.0	-0.9	-1.6	-1.3	-1.8	-1.6	-1.7	-1.8	-0.5	-1.8	-1.5	-1.6
Pain type(s) experienced in last month: Hip pain	1.9	2.4	6.7	1.4	1.9	1.4	2.6	1.5	1.8	0.1	1.7	1.6	1.6	1.6	0.7	1.4	0.5	1.5	1.6	1.6
Ovarian Cancer	1.8	2.4	3.6	-1.8	-1.7	-1.4	-1.9	-1.4	-1.8	-1.4	-1.3	-1.3	-1.7	-1.2	-1.5	-1.6	-1.6	-1.6	-1.2	-1.3
Coronary Artery Disease (CAD)	1.8	2.1	5.7	-2.1	-1.0	-1.2	-1.1	-2.0	-0.7	-0.9	-1.8	-1.1	-0.6	-1.7	-0.4	-1.7	-2.4	-1.7	-1.7	0.0
Illness, injury, bereavement, stress in last 2 years	1.7	2.1	6.5	1.1	2.0	1.3	1.2	1.2	1.4	2.6	1.5	1.3	1.2	1.3	0.8	1.2	1.5	1.2	1.4	1.4
Financial difficulties in last 2 years	1.6	2.1	5.6	-1.3	-2.3	-1.4	-2.4	-1.0	-1.4	-1.1	-1.4	-1.4	-0.9	-1.3	-1.1	-1.2	-1.7	-1.2	-1.4	-1.3
Migraine (self-reported)	1.6	1.9	3.1	-1.7	-0.5	-1.2	-1.3	-1.5	-1.7	0.3	-1.7	-1.3	-1.6	-1.8	-0.6	-1.7	-0.5	-1.7	-1.6	-1.5
Medication: Omeprazole	1.6	1.9	4.0	2.0	1.2	1.1	0.5	1.9	0.7	0.0	2.0	0.7	1.7	1.6	0.8	1.8	0.5	1.7	1.3	1.7
Number of full sisters	1.6	2.0	3.2	1.8	1.3	1.1	1.0	1.3	1.4	0.6	1.7	1.4	1.6	1.6	1.2	1.7	0.4	1.7	1.6	1.5
Ever unenthusiastic/disinterested for a whole week	1.5	1.9	5.1	1.2	1.9	1.3	1.8	1.1	1.3	0.2	1.0	1.4	1.9	1.1	2.3	1.2	1.0	1.2	1.0	1.1
Medication: Ramipril	1.5	1.9	4.1	1.7	0.5	1.4	0.2	1.6	2.0	-0.4	1.5	1.1	1.8	1.5	1.2	1.8	0.5	1.7	1.2	1.6
Medication: Lansoprazole	1.5	1.7	3.1	-1.3	-0.7	-1.5	-1.2	-1.3	-1.6	-1.8	-1.1	-1.3	-1.4	-0.9	-1.1	-1.3	-1.4	-1.3	-1.0	-1.3
Medication for pain relief, constipation, heartburn	1.5	2.5	6.2	-1.7	-2.5	-1.3	-1.4	-1.5	-1.7	1.1	-1.8	-1.1	-2.1	-1.5	-1.8	-1.5	0.2	-1.5	-1.2	-1.6
Medication: Omeprazole (e.g. Zanprol)	1.5	1.9	4.1	2.0	1.3	1.1	0.8	1.8	0.8	0.2	1.9	0.8	1.5	1.6	0.7	1.7	0.7	1.7	1.3	1.6
Mean Putamen Volume	1.4	1.6	3.1	-1.4	-0.9	-1.6	-1.2	-1.4	-1.4	-0.1	-1.2	-1.7	-1.0	-1.4	-1.2	-1.2	-1.8	-1.2	-1.6	0.0
Heel T-Score	1.4	11.5	102.0	-2.8	-3.9	-2.1	-0.1	-3.6	-1.5	-10.1	-2.8	-1.7	-1.7	-2.2	-1.4	-2.6	-2.0	-2.6	-2.3	-2.7
Asthma	1.4	2.8	6.6	1.8	1.9	2.0	0.8	2.0	1.4	2.6	1.5	1.6	0.5	1.9	-0.6	1.8	1.5	1.8	1.8	1.8
Qualifications: O levels/GCSEs or equivalent	1.4	2.3	4.7	1.4	1.3	1.6	0.8	1.6	1.8	1.7	1.3	1.8	1.1	1.3	-0.5	1.6	2.2	1.5	1.6	1.5
Illnesses of siblings: Diabetes	1.4	1.7	4.6	-0.8	-2.1	-1.4	0.6	-1.3	-0.8	-1.3	-1.3	-1.7	-1.0	-1.2	1.3	-1.2	-1.3	-1.2	-1.6	-1.2
Bipolar Disorder (2011)	1.2	1.2	4.6	-1.1	-0.6	-1.0	-0.5	-1.1	-1.1	-0.2	-1.4	-0.8	-1.7	-1.1	-2.1	-1.1	0.6	-1.1	-0.9	0.0
Lung FEV1/FVC ratio	1.2	6.1	17.5	2.5	2.2	2.4	1.4	2.5	4.2	3.4	2.2	2.2	1.4	2.4	1.5	2.5	2.3	2.5	2.4	2.3
Tinnitus: Yes, but not now, but have in the past	1.2	1.3	5.5	-0.7	1.4	-0.9	2.4	-0.4	-1.1	0.1	-0.8	-1.1	-1.4	-0.9	-1.4	-0.8	1.5	-0.9	-1.0	-0.9
Impedance of arm (right)	1.2	5.5	10.5	2.1	1.0	2.9	1.4	2.6	1.5	1.3	2.5	3.2	2.5	2.8	1.0	2.7	2.0	2.7	3.1	2.7
Osteoporosis (self-reported)	1.2	1.5	6.4	1.1	-0.2	1.4	0.8	1.1	0.8	2.5	1.2	1.4	0.7	1.2	0.3	1.2	1.3	1.2	1.3	1.3
Tinnitus: Yes, now most or all of the time	1.2	1.4	2.7	1.3	0.6	1.2	1.2	1.1	1.3	0.2	1.5	1.3	1.6	1.4	0.7	1.2	0.7	1.2	1.4	1.2
Fractured/broken bones in last 5 years	1.2	1.5	3.1	-1.3	-0.6	-1.8	-0.0	-1.1	-1.5	-0.2	-1.2	-1.6	-1.4	-1.4	-0.0	-1.5	-1.1	-1.4	-1.3	-1.3
Pack years of smoking	1.2	1.7	4.8	1.4	0.1	1.3	2.2	1.2	1.0	0.4	1.3	1.3	1.0	1.4	1.8	1.2	1.5	1.2	1.3	1.2
Intelligence (Savage-Jansen 2018)	1.1	3.2	6.8	1.7	1.1	1.9	2.2	1.5	2.1	1.5	1.5	2.2	1.5	1.7	1.9	1.5	2.6	1.6	1.9	1.6
Peak expiratory flow (PEF)	1.1	2.5	9.7	1.5	1.9	1.3	0.6	1.6	3.1	2.0	1.6	1.0	1.9	1.6	0.9	1.5	0.1	1.5	1.2	1.5
Asthma (self-reported)	1.1	2.2	5.1	1.5	1.8	1.7	0.9	1.7	1.3	2.3	1.3	1.4	0.4	1.6	-0.5	1.6	1.2	1.6	1.6	1.6
High cholesterol (Self-reported)	1.1	2.0	4.2	1.2	1.0	2.0	1.2	1.1	1.6	0.9	1.2	2.0	1.7	1.4	2.0	1.3	0.1	1.3	1.5	1.3
Number of operations (self-reported)	1.1	1.6	2.9	-1.3	-0.9	-1.4	-0.2	-1.3	-1.0	-1.7	-1.3	-1.4	-1.2	-1.3	0.8	-1.4	-1.4	-1.4	-1.4	-1.4
Pain experienced in last month	1.1	1.9	4.8	-1.4	-2.2	-1.4	-1.4	-1.3	-1.0	-1.4	-1.2	-1.5	-1.0	-1.4	0.1	-1.3	-1.6	-1.3	-1.5	-1.2
Basal cell carcinoma (self-reported)	1.1	1.3	2.8	1.0	1.7	1.4	0.5	1.2	1.4	0.6	1.1	1.6	1.4	1.0	0.3	1.2	0.1	1.3	1.3	1.2
Alzheimer’s Disease (including proxy)	1.0	1.4	4.0	-1.3	-0.1	-1.2	-0.8	-1.4	-0.9	-0.6	-1.1	-1.4	-1.1	-1.4	-1.1	-1.1	-2.0	-1.2	-1.4	-1.1
Medication: Co-codamol	1.0	1.2	2.1	1.2	-0.3	1.2	0.3	1.3	1.1	0.7	1.2	0.9	1.4	1.3	1.4	1.3	0.2	1.3	1.0	1.2
Bilateral oophorectomy (both ovaries removed)	1.0	1.2	2.6	0.6	1.1	1.3	0.5	0.8	1.3	-0.0	1.1	1.6	1.5	1.6	0.9	1.0	-0.3	1.0	1.4	1.1
Had other major operations	1.0	1.3	3.3	-0.7	-0.6	-1.0	1.6	-1.0	-1.0	-1.8	-0.7	-1.1	-0.2	-0.9	1.7	-1.0	-1.4	-1.0	-1.1	-1.0
Depression (self-reported)	1.0	1.2	2.3	-1.1	-1.5	-1.3	-0.1	-1.2	-1.1	-0.9	-1.1	-1.1	-0.8	-1.2	0.4	-1.1	-1.0	-1.1	-1.1	-1.2
Breastfed as a baby	1.0	1.3	2.9	1.2	1.5	0.9	0.8	1.1	0.0	1.6	1.2	0.9	0.5	1.2	0.0	1.2	1.7	1.2	1.1	1.1
Medication for cholesterol, blood pressure or diabetes	1.0	1.7	3.1	-1.3	-1.0	-1.8	-0.3	-1.5	-1.6	-1.7	-1.3	-1.5	-0.7	-1.3	0.2	-1.4	-1.4	-1.4	-1.4	-1.4
Loneliness, isolation	1.0	1.3	2.9	1.0	0.8	1.2	0.2	1.5	0.7	1.3	1.0	1.4	0.2	1.3	-0.6	1.3	1.7	1.3	1.6	1.1
Commuting to job workplace: Walk	1.0	1.1	1.8	-1.0	-0.2	-1.1	-0.8	-1.1	-0.4	-1.0	-1.3	-1.1	-1.2	-1.3	-1.3	-1.1	-0.4	-1.2	-1.2	-1.2
HDL Cholesterol	0.9	1.6	4.1	1.2	1.1	1.3	1.9	1.3	0.4	2.0	1.2	1.3	0.9	1.3	1.0	1.2	1.3	1.2	1.3	0.0
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.3	-0.6	-0.6	-1.3	1.5	-1.1	-0.8	-1.3	-0.8	-1.3	-0.6	-1.2	0.7	-1.0	-0.9	-1.0	-1.3	-0.9
Family relationship satisfaction	0.9	1.1	2.6	-1.2	0.2	-0.8	-1.3	-0.6	-1.0	1.4	-1.2	-0.7	-1.6	-1.0	-1.6	-1.0	0.2	-1.0	-0.8	-1.0
Medication: Aspirin	0.9	1.1	3.5	1.3	-0.1	0.9	1.2	0.7	1.3	-1.2	1.2	0.5	1.4	0.7	1.9	1.1	-0.1	1.1	0.5	1.1
Primary Biliary Cirrhosis	0.8	1.1	2.8	0.9	1.3	1.0	1.0	1.1	1.1	1.3	0.8	1.1	1.2	0.9	0.9	0.8	1.7	0.8	0.9	0.0
Average weekly spirits intake	0.8	1.0	4.2	1.0	2.1	1.1	1.3	1.0	0.3	0.7	0.9	0.9	0.2	1.0	-0.2	0.8	1.5	0.8	1.0	0.9
Ever had hysterectomy (womb removed)	0.8	0.9	1.6	0.6	1.2	1.2	-1.2	0.8	0.9	0.7	0.6	1.3	0.8	1.2	0.5	0.8	0.9	0.8	1.1	0.9
Angina	0.8	1.1	4.0	-1.0	-1.9	-1.1	0.6	-1.2	-0.6	-0.9	-0.6	-1.2	-0.4	-0.7	0.2	-0.9	-2.0	-0.9	-1.1	-0.8
Pack years adult smoking proportion	0.8	1.2	3.7	1.1	0.0	1.2	1.9	0.9	0.7	0.3	1.0	1.2	0.8	1.2	1.7	0.9	1.3	0.9	1.1	0.9
Pain all over the body in last month	0.8	0.9	2.0	1.4	-0.1	0.9	0.1	1.2	1.1	0.1	1.2	0.6	0.7	1.3	-0.0	1.3	0.3	1.3	1.1	1.0
Medication: Simvastatin	0.8	1.1	4.3	0.9	1.0	1.4	1.4	0.6	0.4	-0.1	0.8	1.5	1.3	0.9	2.1	0.7	0.5	0.7	1.0	0.7
Qualifications: A levels/AS levels or equivalent	0.8	1.7	3.5	1.2	1.7	1.1	1.8	1.5	1.9	0.9	1.2	1.1	1.8	0.8	1.1	1.3	0.3	1.3	0.9	1.2
Impedance of arm (left)	0.8	3.7	6.5	1.6	0.7	2.3	1.6	2.1	1.0	0.8	2.2	2.6	2.1	2.3	0.7	2.3	1.1	2.3	2.5	2.3
Exposure to tobacco smoke at home	0.8	0.9	2.4	-1.0	0.1	-1.2	-0.1	-0.9	-0.9	-0.1	-0.9	-1.3	-1.6	-1.0	-1.3	-1.1	-0.3	-1.1	-1.1	-0.9
Ever highly irritable/argumentative for 2 days	0.8	1.0	4.3	-0.8	0.4	-0.6	-2.1	-0.4	-1.3	0.5	-1.2	-0.6	-1.2	-0.9	-1.5	-0.8	-0.1	-0.8	-0.8	-1.0
Pulse wave peak to peak time	0.8	0.9	7.7	0.0	1.7	0.0	-1.3	0.2	0.1	1.4	-0.2	-0.3	-0.8	-0.3	-2.8	0.1	-0.3	0.1	-0.2	0.1
Alcohol intake frequency.	0.8	1.9	3.3	1.6	0.8	1.5	0.8	0.8	1.8	-0.5	1.8	1.4	1.6	1.6	1.3	1.6	0.4	1.6	1.5	1.7
Eye problems/disorders: Cataract	0.8	0.9	5.8	-0.8	1.0	-0.6	0.3	-1.0	-1.3	2.4	-0.8	-0.4	-1.1	-0.8	-0.6	-0.9	0.4	-0.9	-0.5	-0.8
Financial situation satisfaction	0.8	1.0	2.5	-0.8	-1.5	-0.9	0.0	-0.7	-1.5	-1.1	-0.9	-0.8	-1.6	-1.2	-0.8	-0.9	-0.1	-0.9	-0.9	-0.9
Height	0.7	14.1	47.2	3.4	6.9	3.0	2.0	3.6	6.1	3.1	3.7	3.3	2.9	3.3	1.8	3.3	3.9	3.3	3.6	3.4
Illnesses of siblings	0.7	1.0	2.1	-1.0	-0.3	-1.2	-0.1	-0.7	-1.4	0.5	-1.1	-1.0	-1.2	-1.4	-0.6	-1.1	-0.3	-1.1	-1.1	-1.2
Pulse wave Arterial Stiffness index	0.7	0.9	7.6	0.1	-1.3	0.1	1.4	-0.1	0.2	-1.3	0.4	0.4	0.9	0.4	2.8	-0.0	0.5	0.0	0.3	0.0
Hair/balding pattern: Pattern 4	0.7	1.8	3.6	1.8	0.9	1.1	0.7	1.9	1.1	1.0	1.5	0.9	1.5	1.3	1.4	1.5	1.4	1.5	1.2	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	5.2	0.6	-0.7	0.0	0.3	0.5	-0.4	-1.3	0.8	-0.1	1.5	0.6	2.3	0.5	-1.0	0.6	0.3	0.5
Illnesses of father: High blood pressure	0.7	0.8	1.8	1.2	0.2	0.6	-0.0	0.7	0.4	1.0	1.3	0.7	0.8	1.2	1.3	1.0	-0.2	1.0	1.1	1.2
Diabetes (mother)	0.6	0.8	2.0	1.1	-0.2	0.7	-0.5	0.7	0.6	-0.7	1.3	0.5	1.4	1.1	1.0	1.0	0.0	1.1	0.9	1.0
Severe depression (siblings)	0.6	0.7	3.6	0.5	-0.1	0.3	0.7	0.2	0.6	-1.9	0.6	0.1	1.3	0.5	1.8	0.4	-0.7	0.4	0.1	0.4
Age when periods started (menarche)	0.6	1.5	4.4	1.4	-1.0	1.3	-1.7	1.2	0.2	0.2	1.2	1.2	0.7	1.4	0.9	1.1	2.1	1.1	1.4	1.2
Medication: Atenolol	0.6	0.8	2.5	1.1	0.6	0.9	0.4	0.8	1.4	1.5	0.8	0.7	0.7	0.3	1.6	0.8	0.5	0.7	0.5	0.8
Heart attack	0.6	0.8	2.9	-0.4	-1.7	-1.0	-0.3	-0.6	-0.3	-1.4	-0.5	-1.2	-1.1	-1.0	-0.3	-0.5	-0.6	-0.6	-1.0	-0.6
Fluid intelligence score	0.6	1.3	2.0	-1.3	-1.3	-1.2	-0.8	-1.3	-1.2	-0.8	-1.3	-0.9	-0.8	-1.4	-0.7	-1.4	-1.1	-1.4	-1.2	-1.3
Forced vital capacity (FVC), Best measure	0.6	2.4	9.8	1.3	3.1	1.4	-0.3	1.6	2.1	1.3	1.4	1.3	1.9	1.5	0.7	1.4	0.9	1.4	1.3	1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	3.8	0.9	-0.4	0.8	1.3	0.4	0.5	0.6	0.7	0.7	0.7	0.8	1.9	0.7	1.2	0.7	0.7	0.7
Eye problems/disorders: None of the above	0.6	0.7	3.2	0.8	-0.8	0.6	-1.1	0.8	0.5	-1.8	0.8	0.6	0.6	0.9	-0.5	0.9	0.3	0.9	0.8	0.8
Emphysema/chronic bronchitis	0.6	0.7	1.3	-0.9	-0.3	-1.1	0.5	-0.7	-1.0	-0.4	-0.9	-1.0	-1.1	-0.9	-0.1	-0.9	-0.3	-0.9	-0.9	-1.0
Had major operations	0.6	0.7	2.3	1.0	-0.2	0.6	0.5	1.0	1.2	1.5	0.8	0.2	0.1	0.7	0.5	0.9	0.9	0.8	0.6	0.9
Mineral and other dietary supplements	0.6	0.9	4.1	-0.4	-1.7	-0.6	-1.9	-0.5	-1.2	-2.0	-0.6	-0.3	-0.9	-0.2	-0.2	-0.4	0.1	-0.3	-0.1	-0.6
Eye problems/disorders: Glaucoma	0.6	0.7	1.9	0.8	-0.2	1.1	0.7	0.6	0.7	1.1	0.7	1.0	0.9	0.9	1.4	0.7	1.0	0.7	0.8	0.7
Medication: Atorvastatin	0.6	0.7	2.4	-0.9	-1.5	-0.9	-0.5	-0.5	0.4	0.0	-0.5	-1.1	-0.4	-0.6	-1.1	-0.6	-1.6	-0.6	-0.9	-0.6
Unable to work because of sickness or disability	0.6	0.8	2.5	-0.8	-1.6	-0.8	0.1	-0.7	-0.6	-1.0	-1.0	-0.7	-1.3	-0.8	-0.5	-0.9	0.6	-0.9	-0.7	-1.1
Breast Cancer	0.5	1.3	3.3	0.7	1.4	1.5	-0.5	1.2	0.8	-0.2	1.0	1.8	1.4	1.4	0.5	1.0	0.7	1.1	1.5	1.2
HbA1C	0.5	0.6	4.6	0.1	-0.1	-0.0	-0.5	-0.2	-0.2	0.7	-0.5	2.1	-0.5	-0.4	-0.6	0.0	0.7	0.2	1.8	0.0
Ulcerative Colitis	0.5	0.7	5.4	-0.6	-0.8	-0.3	-1.4	-0.7	0.6	-2.3	-0.4	-0.3	0.1	-0.1	-0.7	-0.3	-0.9	-0.3	-0.2	0.0
Systolic Blood Pressure	0.5	2.7	9.1	1.2	-3.0	0.8	1.0	0.7	0.9	-2.2	1.6	0.5	2.5	1.3	2.7	1.5	-1.2	1.5	0.9	1.4
Cardiovascular Disease	0.5	1.6	9.3	-1.3	-1.1	-1.0	-1.0	-1.1	-0.3	-3.1	-1.1	-1.2	-1.0	-0.9	-0.7	-1.0	-1.5	-1.1	-1.2	-0.9
Other serious medical condition/disability diagnosed by doctor	0.5	0.6	1.5	-0.2	-1.1	-1.1	-1.0	-0.5	-1.2	1.0	-0.3	-1.0	-1.2	-0.7	-0.1	-0.5	0.4	-0.5	-0.6	-0.5
Systolic blood pressure, automated reading	0.5	1.4	10.5	0.2	-3.2	0.0	0.6	-0.3	0.0	-1.6	0.6	-0.3	1.2	0.2	2.4	0.4	-1.4	0.4	-0.1	0.5
Supplements: Zinc	0.5	0.5	2.6	-0.6	1.2	-0.4	0.9	-0.6	0.5	1.6	-0.4	-0.3	-0.7	-0.6	-0.7	-0.5	0.4	-0.5	-0.4	-0.6
Fed-up feelings	0.5	0.8	2.9	0.7	1.1	0.8	1.3	0.5	-0.1	0.6	0.9	0.9	1.2	0.7	1.7	0.8	0.8	0.8	0.9	0.8
Qualifications: CSEs or equivalent	0.5	0.6	1.8	-0.7	-1.2	-0.7	-0.1	-0.9	-0.4	-1.2	-0.8	-0.6	-1.3	-0.5	-1.0	-0.8	0.1	-0.8	-0.5	-0.7
Hair/balding pattern: Pattern 2	0.5	0.6	2.0	-1.0	-0.1	-0.5	-1.1	-0.9	-0.0	-1.4	-1.0	-0.5	-0.5	-0.8	-0.1	-0.9	-0.8	-0.9	-0.8	-0.8
Allergy	0.5	1.1	2.1	-1.2	-1.1	-1.0	-0.6	-1.4	-1.3	-1.3	-1.1	-0.6	-0.1	-0.9	0.8	-1.3	-0.6	-1.3	-1.0	-1.3
Number of live births	0.5	0.7	1.7	0.8	0.3	1.1	0.7	0.8	0.9	-0.2	0.7	1.0	1.0	1.0	1.3	0.9	0.5	0.9	0.9	0.9
Medication: Ibuprofen (e.g. Nurofen)	0.5	0.7	1.7	-0.6	0.3	-1.2	-0.3	-0.4	-0.8	-0.5	-0.7	-1.2	-0.6	-0.9	-0.5	-0.8	-1.3	-0.8	-1.0	-0.8
Medication: Cholesterol lowering	0.5	0.8	1.8	0.9	0.1	1.2	0.9	0.8	1.3	0.7	1.0	1.0	0.9	0.8	0.8	0.9	0.2	0.9	0.8	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.7	6.2	1.0	2.5	1.1	-0.7	1.3	2.4	1.6	1.1	0.9	1.4	1.1	0.5	1.1	0.6	1.1	1.0	1.1
Standing height	0.5	5.0	23.8	1.6	4.9	1.6	2.0	1.8	4.1	0.8	1.9	1.8	2.0	1.7	1.8	1.6	1.8	1.6	1.8	1.6
Birth weight of first child	0.5	0.8	6.6	0.3	1.4	0.6	-1.3	0.3	0.8	0.1	0.0	0.5	-0.9	0.6	-2.6	0.4	0.7	0.4	0.6	0.4
Pulse wave reflection index	0.5	0.6	3.7	-0.0	-1.9	-0.5	-0.4	-0.3	-0.8	-0.8	0.1	-0.3	0.2	0.1	1.9	-0.2	0.3	-0.2	-0.0	-0.3
Number of full brothers	0.5	0.6	1.8	-0.8	1.0	-0.8	1.3	-0.5	0.2	-0.4	-0.6	-0.7	-0.4	-0.9	0.0	-0.8	-1.3	-0.8	-0.8	-0.7
Health satisfaction	0.5	0.7	1.8	1.0	1.1	0.9	0.4	1.0	0.4	1.4	0.5	0.9	-0.0	0.8	-0.3	0.7	1.3	0.7	0.9	0.6
Angina (self-reported)	0.5	0.7	2.7	-0.7	-1.6	-0.7	0.9	-1.0	-0.2	-0.7	-0.4	-0.9	-0.4	-0.5	0.3	-0.6	-1.6	-0.6	-0.8	-0.6
Heart disease (mother)	0.5	0.6	2.0	-0.7	-0.2	-0.8	-0.3	-0.9	-0.8	-0.4	-1.0	-0.9	-1.4	-0.8	-0.2	-0.9	0.1	-0.9	-0.8	-0.9
Leg pain on walking	0.5	0.6	2.5	1.1	-0.4	0.1	1.6	1.0	0.4	-0.2	1.0	-0.1	0.7	0.4	1.5	0.8	0.0	0.8	0.4	0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	4.3	0.9	1.7	0.5	2.1	0.8	2.1	0.1	0.8	0.2	0.2	0.4	0.2	0.8	0.5	0.7	0.5	0.8
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.9	0.8	0.3	0.7	0.4	0.6	1.4	-0.3	0.8	0.9	1.3	0.7	1.2	0.8	0.3	0.8	0.8	0.7
Medication for cholesterol	0.5	0.7	4.2	0.5	0.8	0.4	0.8	0.7	0.8	2.0	0.5	0.6	-0.4	0.5	-1.5	0.5	1.1	0.5	0.8	0.6
Alcohol drinker status: Never	0.5	0.6	1.5	0.6	0.1	1.1	0.8	0.4	0.4	0.5	0.7	1.2	0.7	0.8	0.1	0.8	0.9	0.8	1.1	0.8
Ever depressed for a whole week	0.5	0.6	3.7	0.4	1.1	0.5	0.7	0.5	0.5	-1.2	0.3	0.4	0.8	0.3	1.9	0.4	1.1	0.4	0.2	0.3
Cholesterol lowering medication	0.5	0.7	5.3	-0.3	-0.4	-0.1	0.3	-0.4	-0.4	-2.1	-0.4	-0.0	0.5	-0.4	2.3	-0.4	-0.6	-0.4	-0.4	-0.5
Impedance of whole body	0.5	2.4	4.8	1.0	1.0	1.8	1.9	1.5	0.6	0.8	1.6	2.2	2.0	1.8	0.9	1.7	0.8	1.8	2.0	1.7
Schizophrenia (2018)	0.4	0.7	2.8	1.0	0.7	0.8	-0.3	1.0	0.9	1.7	1.0	0.5	0.6	0.7	0.4	1.0	0.9	1.0	0.7	0.0
Alzheimer’s Disease (in mother)	0.4	0.4	1.4	-0.9	0.1	-0.6	-0.3	-0.7	-1.0	-0.3	-0.6	-0.6	-0.5	-0.7	-0.7	-0.6	-1.2	-0.6	-0.7	-0.5
Alzheimer’s Disease (in father)	0.4	0.4	1.2	-0.2	-0.9	-0.6	-0.9	-0.7	-0.1	-0.1	-0.3	-0.7	0.3	-0.5	1.1	-0.4	-1.1	-0.4	-0.6	-0.4
Prostate Cancer	0.4	0.5	1.2	0.8	-0.1	1.0	-0.0	0.5	0.7	0.4	0.7	0.9	0.6	0.8	-0.1	0.8	1.1	0.8	0.9	0.7
Lupus	0.4	0.6	1.6	0.7	-0.7	0.7	1.0	0.7	1.2	1.2	0.5	0.6	0.0	0.5	0.5	0.6	1.1	0.6	0.6	0.6
Rheumatoid Arthritis	0.4	0.5	1.8	-0.5	0.1	-0.9	-0.7	-0.6	-1.2	0.1	-0.3	-0.9	-0.3	-0.5	-1.4	-0.5	-1.3	-0.5	-0.7	0.0
Schizophrenia (2014)	0.4	1.0	5.0	1.0	1.2	0.9	0.1	1.0	1.1	2.2	0.9	0.7	0.6	0.8	0.2	0.9	1.3	0.9	0.8	0.0
Triglycerides	0.4	0.7	2.7	-0.8	-0.4	-1.2	0.0	-0.8	-0.7	-0.7	-0.7	-1.2	-0.5	-0.9	-0.1	-0.8	-1.6	-0.8	-1.0	0.0
Type 2 Diabetes (T2D) (2012)	0.4	0.5	2.1	-0.5	-0.1	-0.7	-0.3	-0.7	-1.1	-1.1	-0.4	-0.6	-0.6	-0.5	-1.4	-0.6	-0.6	-0.6	-0.5	0.0
Allergy or Eczema	0.4	1.1	1.8	1.1	0.7	1.2	1.1	1.2	1.4	0.6	1.0	1.1	0.7	0.9	0.4	1.2	0.8	1.2	1.1	1.3
Number of treatments/medications taken	0.4	0.7	1.2	1.0	1.1	1.1	-0.2	0.9	0.7	0.2	0.7	0.9	1.1	0.7	1.0	0.9	0.6	0.8	0.7	0.8
Relative age voice broke	0.4	0.6	1.2	0.8	0.2	0.6	0.3	0.8	0.7	-1.1	0.9	0.6	0.8	1.0	-0.4	0.9	-0.8	0.9	0.8	0.8
Supplements: Glucosamine	0.4	0.5	1.5	-0.4	0.3	-1.0	1.0	-0.3	-0.6	1.0	-0.1	-1.2	-0.1	-0.7	-0.3	-0.5	-0.8	-0.5	-1.0	-0.3
Past tobacco smoking	0.4	0.7	3.8	-0.6	-1.3	-1.3	-0.8	-0.5	-0.9	-0.2	-0.2	-1.1	-0.2	-0.6	-0.4	-0.5	-2.0	-0.5	-0.6	-0.5
Qualifications: None of the above	0.4	0.9	2.9	-0.7	-1.7	-0.7	-1.2	-1.0	-1.3	-1.7	-0.5	-0.6	-0.5	-0.3	0.6	-0.7	-1.3	-0.7	-0.4	-0.7
Hip circumference	0.4	1.8	9.5	1.3	2.0	0.7	1.7	0.9	3.1	-1.9	1.0	0.7	0.6	0.9	1.0	0.8	0.4	0.8	0.9	0.8
Worrier / anxious feelings	0.4	0.8	1.6	-1.0	-1.1	-0.9	-1.3	-1.0	-1.2	-0.4	-1.0	-0.6	-0.6	-0.7	-0.7	-0.8	-1.0	-0.8	-0.7	-0.9
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	6.4	0.6	2.5	0.8	-1.2	1.0	2.4	0.9	0.7	0.6	1.1	0.9	0.1	0.7	-0.1	0.7	0.6	0.6
Happiness	0.4	0.5	2.4	-0.2	1.2	0.1	1.3	0.1	0.0	1.6	-0.3	0.3	-0.6	-0.1	-0.7	-0.2	1.1	-0.2	0.2	-0.2
Noisy workplace	0.4	0.5	2.2	-0.1	-0.9	-0.7	1.5	-0.0	-0.2	-1.3	-0.2	-0.7	-0.1	-0.5	1.1	-0.3	-0.4	-0.3	-0.5	-0.4
Illnesses of mother	0.4	0.4	1.2	0.3	-0.4	0.5	-1.1	0.4	0.6	0.7	0.7	0.7	0.8	0.7	-0.8	0.6	-0.5	0.6	0.7	0.7
Blood clot in the leg (DVT)	0.4	0.5	2.2	0.7	0.7	0.8	-0.3	0.6	0.9	0.5	0.5	0.6	0.0	0.8	-1.5	0.7	0.6	0.7	0.7	0.6
High blood pressure (siblings)	0.4	0.6	1.3	0.7	0.3	0.9	-0.7	0.3	1.1	-0.1	0.8	0.7	0.8	1.0	-0.7	0.8	-0.1	0.8	0.9	0.9
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.0	0.9	-0.5	1.0	0.1	0.4	0.4	-0.2	0.7	0.8	0.9	0.6	0.4	0.8	0.6	0.7	0.7	0.7
Medication: Blood pressure	0.4	0.7	1.7	0.8	0.6	0.9	-1.2	0.9	0.5	1.3	0.7	0.8	0.1	0.8	-0.5	0.8	1.2	0.8	0.9	0.9
Chest pain or discomfort	0.4	0.6	5.6	0.3	2.4	0.4	0.7	0.8	0.5	0.6	0.6	0.3	-0.1	0.4	-0.6	0.5	0.1	0.5	0.5	0.6
Illnesses of father: Heart disease	0.4	0.5	2.3	0.4	-1.3	-0.1	0.3	-0.2	0.4	-1.5	0.3	-0.4	0.7	0.1	1.1	0.2	-1.5	0.2	-0.2	0.1
Mood swings	0.4	0.8	2.0	0.8	0.1	1.1	0.4	0.7	-0.0	1.4	0.9	1.2	0.7	1.1	0.6	0.9	0.9	0.9	1.1	0.9
Qualifications: nursing, teaching	0.4	0.6	4.0	0.3	2.0	0.4	1.2	0.4	0.4	-0.1	0.0	0.4	0.9	0.1	1.4	0.3	0.6	0.3	0.0	0.1
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.7	-0.6	-1.3	-0.7	-0.5	-0.8	-1.1	-0.8	-0.5	-0.8	-0.7	-0.8	-0.4	-0.6	-0.7	-0.6	-0.8	-0.6
Mother’s age at death	0.4	0.5	3.4	-0.4	1.9	-0.2	0.8	-0.2	-0.1	-0.5	-0.5	-0.2	0.0	-0.6	1.3	-0.3	0.3	-0.4	-0.5	-0.4
Commuting to job workplace: Public transport	0.4	0.4	2.4	0.1	1.6	0.3	0.1	0.1	-0.4	1.2	-0.3	0.4	-0.7	0.0	-1.0	0.1	1.1	0.1	0.2	0.0
Supplements: Fish oil (including cod liver oil)	0.4	0.5	3.5	-0.1	1.0	0.1	1.9	-0.2	0.6	1.3	0.2	-0.1	0.6	-0.2	0.0	-0.1	-1.0	-0.1	-0.3	0.1
Diastolic blood pressure, automated reading	0.4	1.1	3.7	1.2	-0.3	1.1	1.9	1.1	1.1	-0.0	1.2	0.8	0.9	1.0	1.1	1.2	0.3	1.1	0.9	1.3
Commuting to job workplace: Cycle	0.4	0.4	3.1	-0.4	1.7	-0.2	0.1	-0.1	-0.2	1.8	-0.4	-0.1	-0.3	-0.3	-0.6	-0.3	0.2	-0.3	-0.1	-0.4
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.8	-0.2	-1.4	-0.9	-0.5	-0.4	-0.3	-1.1	-0.4	-1.1	-0.9	-0.9	-0.3	-0.4	-0.4	-0.4	-0.8	-0.5
Neuroticism (Nagel 2018)	0.3	0.6	2.3	-1.0	-1.5	-0.5	-0.5	-1.1	-1.5	0.2	-0.8	-0.4	-0.6	-0.5	0.0	-0.8	-0.1	-0.8	-0.6	-0.8
Schizophrenia vs Biploar Disorder	0.3	0.4	2.5	0.7	-0.2	0.6	-0.3	0.7	0.3	1.6	0.5	0.6	0.4	0.4	0.6	0.6	1.1	0.6	0.6	0.0
Worry (Nagel 2018)	0.3	0.7	2.7	-1.0	-1.6	-0.6	-0.3	-1.1	-1.3	0.2	-0.9	-0.2	-0.0	-0.6	0.1	-0.8	-1.0	-0.7	-0.6	-0.8
Irritable Bowel Disease (IBD)	0.3	0.6	6.5	-0.4	-0.8	-0.8	-0.5	-0.3	0.2	-2.6	-0.4	-0.9	-0.3	-0.3	0.1	-0.4	-0.8	-0.4	-0.5	-0.4
Ulcerative Colitis (UC)	0.3	0.6	5.1	-0.5	-0.9	-0.5	-1.3	-0.3	0.1	-2.3	-0.5	-0.6	-0.4	-0.3	-0.7	-0.4	-0.2	-0.4	-0.4	-0.4
Reaction Time	0.3	0.6	4.8	0.5	-0.3	0.3	-0.9	0.2	-0.4	1.6	0.3	0.1	-0.9	0.5	-2.2	0.3	0.6	0.3	0.5	0.4
LDL Cholesterol	0.3	0.4	2.1	0.1	-0.8	0.4	0.9	0.3	0.8	-0.6	0.1	0.2	1.2	0.4	1.4	0.1	-0.7	0.1	-0.0	0.0
Blood Eosinophil Count	0.3	2.4	8.0	-1.6	0.7	-1.1	-1.3	-1.0	-1.5	0.5	-1.8	-1.3	-2.7	-1.4	-2.8	-1.5	0.4	-1.5	-1.4	-1.5
Type 2 Diabetes (T2D) (2018)	0.3	0.5	2.7	0.6	0.6	0.5	1.6	0.4	1.1	0.2	0.7	0.3	0.8	0.7	0.8	0.4	-0.4	0.4	0.3	0.5
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.0	-0.8	-0.3	-0.4	0.5	-0.7	-1.0	0.1	-1.0	-0.2	-0.9	-0.7	-0.5	-0.7	0.2	-0.7	-0.5	-0.9
Diabetes (father)	0.3	0.4	3.1	-0.0	-0.3	-0.5	1.8	-0.3	-0.5	-1.3	-0.1	-0.7	-0.5	-0.5	0.1	-0.2	-0.2	-0.3	-0.5	-0.3
Hayfever, allergic rhinitis or eczema	0.3	0.6	1.2	0.8	0.8	0.7	0.5	1.1	1.1	0.6	0.7	0.5	0.1	0.4	-0.2	1.0	0.8	0.9	0.6	1.0
Multivitamins +/- minerals	0.3	0.4	1.7	0.4	-0.6	0.4	0.1	0.1	1.0	0.5	0.7	0.1	1.3	0.4	1.0	0.4	-1.2	0.4	0.1	0.6
Sitting height	0.3	2.1	13.1	-0.2	3.2	-0.0	1.0	-0.2	3.6	-2.7	0.1	0.2	0.7	-0.2	1.8	-0.3	-0.1	-0.3	-0.1	-0.2
Chronic bronchitis/emphysema (father)	0.3	0.4	3.0	-0.3	-1.0	-0.1	-1.7	0.0	-1.0	-0.3	-0.2	-0.1	0.2	-0.1	-0.4	-0.2	-0.7	-0.2	-0.1	-0.1
Forced vital capacity (FVC)	0.3	1.1	6.4	0.6	2.5	0.8	-1.1	0.9	1.9	0.7	0.7	0.7	1.2	0.9	0.1	0.7	0.2	0.7	0.8	0.6
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.3	-0.5	-0.0	-0.6	0.9	-0.5	-0.3	-1.1	-0.3	-0.5	-0.8	-0.7	-1.1	-0.4	0.4	-0.4	-0.4	-0.3
Hair/balding pattern: Pattern 3	0.3	0.5	3.5	-0.3	-0.9	-0.6	-0.6	-0.1	-1.0	-0.5	0.0	-0.8	0.1	-0.2	0.6	-0.2	-1.9	-0.2	-0.5	-0.1
Pulse rate	0.3	0.5	1.7	0.7	1.0	1.0	0.2	0.9	0.8	0.4	0.5	0.8	0.2	0.9	0.1	0.7	1.3	0.7	0.6	0.7
Mouth/teeth dental problems: Dentures	0.3	0.5	2.1	0.5	1.5	0.7	1.1	0.6	0.2	1.3	0.3	0.8	0.2	0.6	0.7	0.4	0.2	0.5	0.7	0.5
Prospective memory result	0.3	0.4	0.9	-0.9	0.8	-0.5	0.2	-0.9	-0.3	-0.5	-0.7	-0.3	-1.0	-0.5	-0.5	-0.7	-0.5	-0.7	-0.5	-0.5
Length of working week for main job	0.3	0.4	1.2	-0.1	-1.1	-0.2	0.5	-0.3	-0.5	-0.5	-0.5	-0.4	-0.8	-0.4	-1.1	-0.4	1.0	-0.4	-0.5	-0.4
Loud music exposure frequency	0.3	0.3	1.7	0.5	0.1	0.3	1.3	0.3	0.5	0.2	0.6	0.3	-0.2	0.5	-0.5	0.5	0.7	0.5	0.6	0.5
Medication: Paracetamol	0.3	0.5	2.2	0.4	1.5	0.5	0.4	0.2	0.5	-1.1	0.7	0.8	0.7	0.5	-0.0	0.5	-0.8	0.5	0.7	0.6
Medication: Amlodipine	0.3	0.5	1.5	-0.7	-0.2	-0.7	-0.6	-0.8	-1.2	-0.4	-0.6	-1.0	-0.7	-0.7	-0.2	-0.7	-0.1	-0.7	-0.9	-0.7
Birth weight	0.3	0.7	7.0	-0.1	-0.8	-0.5	2.7	-0.2	0.4	-1.4	-0.0	-0.7	0.1	-0.7	0.3	-0.2	-0.6	-0.3	-0.7	-0.3
Shortness of breath walking on level ground	0.3	0.4	1.5	0.7	1.2	0.6	0.5	0.5	0.6	-0.2	0.4	0.7	0.1	0.4	0.8	0.4	1.0	0.4	0.6	0.4
Medication: Ibuprofen	0.3	0.3	0.8	-0.4	0.8	-0.9	-0.2	-0.2	-0.7	0.1	-0.6	-0.8	-0.6	-0.6	-0.5	-0.6	-0.5	-0.6	-0.7	-0.6
Medication: Seretide 50 evohaler	0.3	0.3	1.2	-0.5	-0.7	-0.1	-1.1	-0.2	-0.2	-0.2	-0.7	-0.2	-1.1	-0.5	-0.8	-0.4	-0.1	-0.4	-0.3	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	2.0	0.6	-0.3	0.3	-0.4	0.6	0.4	0.4	0.6	0.1	0.9	0.4	1.4	0.5	-0.0	0.5	0.2	0.5
Friendships satisfaction	0.3	0.3	1.5	-0.4	-0.1	0.1	0.5	0.0	-0.8	1.0	-0.4	0.4	-0.8	0.1	-1.2	-0.2	0.8	-0.1	0.3	-0.3
Illnesses of father: None of the above (group 1)	0.3	0.3	0.6	-0.8	0.6	-0.3	0.8	-0.0	-0.1	0.5	-0.7	-0.2	-0.8	-0.7	-0.7	-0.6	0.4	-0.6	-0.6	-0.4
Wears glasses or contact lenses	0.3	0.3	1.5	-0.1	1.0	0.1	1.1	0.2	0.1	-0.0	-0.1	0.4	-0.0	0.1	1.2	-0.2	1.1	-0.2	0.2	-0.2
Medication: Blood pressure	0.3	0.5	2.4	0.6	-0.5	0.6	-0.8	0.3	0.3	-1.6	0.6	0.5	1.1	0.6	1.3	0.7	0.0	0.6	0.5	0.5
Medication: Paracetamol	0.3	0.4	2.6	0.3	1.3	0.3	-0.1	-0.0	0.2	-1.6	0.5	0.6	0.6	0.5	0.3	0.3	-0.4	0.3	0.6	0.4
Ever smoked	0.3	0.5	3.0	0.1	1.3	0.6	1.3	-0.1	0.3	-0.4	-0.1	0.5	-0.2	0.0	0.6	-0.0	1.7	-0.0	0.1	0.1
Irritability	0.3	0.5	4.5	0.1	0.8	0.6	-0.7	0.1	0.4	2.1	0.4	0.6	0.7	0.6	0.1	0.4	0.4	0.4	0.5	0.4
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.3	0.5	0.5	0.6	0.7	0.2	0.8	0.4	0.3	0.5	0.7	0.3	1.2	0.4	0.9	0.4	0.3	0.4
Bipolar Disorder or Schizophrenia	0.2	0.4	2.2	0.4	0.7	0.5	-0.6	0.5	0.4	1.5	0.5	0.4	0.2	0.5	0.2	0.5	1.0	0.5	0.5	0.0
Depressed Affect (Nagel 2018)	0.2	0.5	1.4	0.5	-0.0	0.7	0.7	0.5	-0.4	1.2	0.6	0.9	0.3	0.8	0.1	0.7	0.9	0.7	0.9	0.6
Depression (Nagel 2018)	0.2	0.4	2.2	-0.5	-0.6	-0.4	0.5	-0.6	-1.5	0.7	-0.6	-0.3	-0.6	-0.5	-0.2	-0.5	-0.1	-0.5	-0.4	-0.6
Crohns Disease (2017)	0.2	0.4	2.3	-0.3	0.2	-0.6	0.9	-0.3	0.1	-1.5	-0.2	-0.7	-0.1	-0.3	0.9	-0.4	-0.8	-0.3	-0.5	-0.3
Verbal and Numeric Reasoning (VNR)	0.2	0.5	2.2	0.5	0.5	0.6	1.5	0.6	0.9	1.1	0.2	0.9	0.5	0.2	0.8	0.4	1.2	0.4	0.5	0.2
Age at First Birth	0.2	0.3	1.0	0.7	0.6	0.6	-1.0	0.6	-0.3	0.3	0.5	0.3	0.3	0.7	-0.8	0.6	0.6	0.6	0.6	0.0
Fasting Glucose	0.2	0.2	1.4	-0.7	-0.0	-0.2	-1.2	-0.4	-0.1	0.2	-0.5	-0.2	-0.3	-0.3	-0.5	-0.5	-0.2	-0.4	-0.3	-0.4
Blood Red Count	0.2	2.1	12.5	1.4	-0.3	1.1	3.5	1.2	1.5	-1.0	1.5	1.0	1.1	1.2	1.1	1.3	1.0	1.3	1.2	1.4
Blood White Count	0.2	1.7	2.8	1.2	1.1	1.6	1.0	1.5	0.6	1.4	1.3	1.4	1.5	1.3	1.7	1.3	0.5	1.3	1.2	1.4
Hypothyroidism (self reported)	0.2	0.4	1.0	-0.6	0.5	-0.3	0.2	-0.6	0.2	0.5	-1.0	-0.5	-0.8	-0.8	-0.3	-0.9	0.1	-0.9	-0.8	-0.8
Respiratory disease	0.2	0.4	2.3	0.1	1.5	0.4	1.3	0.1	-0.1	0.8	-0.0	0.2	-0.4	0.2	-1.2	0.2	-0.2	0.2	0.2	0.2
Lung FVC	0.2	1.2	7.3	1.0	0.3	0.6	-2.7	1.2	0.3	1.2	1.2	0.3	1.1	1.0	0.9	1.0	0.4	1.0	0.8	1.1
Neuroticism	0.2	0.4	1.6	-0.7	-1.3	-0.2	-0.6	-0.9	-1.0	0.6	-0.6	0.3	-0.0	-0.4	0.3	-0.5	-0.4	-0.4	-0.1	-0.6
Chronotype (morning person)	0.2	0.4	3.1	0.4	-1.8	0.1	-0.7	0.2	0.0	-0.4	0.4	0.3	0.4	0.3	1.3	0.4	-0.1	0.4	0.5	0.3
Hair Pigment	0.2	5.3	11.7	2.0	3.3	2.5	1.2	2.0	2.3	3.4	1.9	2.7	1.6	2.2	0.8	2.0	3.0	2.0	2.4	2.2
Hand grip strength (left)	0.2	0.5	3.2	0.4	0.0	0.1	-0.8	0.1	0.3	-1.2	0.4	0.1	1.4	0.3	1.8	0.2	-0.3	0.2	0.1	0.2
Hearing difficulty/problems: Yes	0.2	0.3	1.3	0.6	0.3	0.2	1.0	0.5	0.1	-1.1	0.8	-0.2	0.7	0.3	-0.5	0.7	-0.4	0.7	0.2	0.5
Relative age of first facial hair	0.2	0.4	1.7	0.1	-0.0	0.7	-0.5	-0.1	0.9	-0.7	0.1	0.7	0.9	0.4	1.3	0.2	-0.8	0.2	0.4	0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.2	1.4	0.1	0.0	-0.2	0.8	-0.1	-0.6	-0.8	0.2	-0.3	0.1	0.1	1.2	0.1	-0.1	0.0	-0.2	0.1
Eye problems/disorders: Diabetes related eye disease	0.2	0.2	0.7	-0.4	-0.8	-0.4	0.0	-0.1	-0.3	-0.0	-0.4	-0.8	-0.6	-0.6	0.4	-0.5	-0.6	-0.5	-0.7	-0.4
Medication for hormone replacement therapy	0.2	0.2	1.6	0.3	0.3	0.2	1.3	0.2	0.0	-0.1	0.4	-0.0	0.8	0.4	-0.1	0.3	-0.7	0.3	0.0	0.3
Vitamin and mineral supplements	0.2	0.2	1.3	0.1	0.5	-0.0	0.6	0.4	0.0	-0.9	-0.4	0.0	-0.8	-0.0	-0.1	0.0	1.1	0.0	0.1	-0.2
Impedance of leg (right)	0.2	0.9	4.6	0.1	1.2	0.8	2.1	0.6	-0.2	0.2	0.6	1.4	1.2	0.9	1.0	0.7	0.5	0.7	1.2	0.6
Trunk fat percentage	0.2	0.8	7.6	0.6	-0.3	0.4	1.1	0.5	1.2	-2.8	0.7	0.2	0.2	0.6	0.9	0.4	-0.7	0.4	0.5	0.6
Hand grip strength (right)	0.2	0.5	3.0	0.6	0.1	-0.2	-0.7	0.1	0.2	-1.7	0.6	-0.1	1.0	0.4	1.5	0.3	-0.3	0.3	0.2	0.4
Current tobacco smoking	0.2	0.3	2.1	0.3	-0.1	0.2	1.5	0.2	-0.2	-0.0	0.3	0.3	-0.0	0.1	1.4	0.1	1.0	0.1	0.2	0.2
Average weekly fortified wine intake	0.2	0.3	1.9	-0.7	-0.1	-0.4	-0.2	-0.7	-1.4	0.0	-0.6	-0.2	-0.3	-0.3	-0.4	-0.6	-0.1	-0.6	-0.4	-0.6
Body mass index (BMI)	0.2	0.9	7.3	-0.0	-1.1	-0.8	0.1	-0.5	0.4	-2.7	-0.3	-1.1	-0.8	-0.6	0.3	-0.6	-1.4	-0.6	-0.8	-0.5
Impedance of leg (left)	0.2	0.9	5.8	-0.0	1.1	0.6	2.4	0.4	-0.4	0.6	0.6	1.2	1.2	0.7	1.1	0.5	0.4	0.6	0.9	0.5
Trunk fat mass	0.2	0.9	5.9	0.9	0.5	0.4	1.1	0.6	1.9	-2.4	0.9	0.2	0.3	0.7	0.9	0.6	-0.3	0.6	0.5	0.7
Alcohol usually taken with meals	0.2	0.3	3.3	0.0	1.8	-0.1	0.6	0.5	0.7	0.1	-0.2	-0.2	0.3	-0.2	-0.2	0.1	0.3	0.1	-0.4	-0.1
Hearing difficulty/problems with background noise	0.2	0.3	0.9	-0.4	-0.4	-0.5	0.6	-0.6	-0.8	-1.0	-0.3	-0.7	-0.4	-0.6	0.0	-0.4	-0.2	-0.4	-0.6	-0.4
Had menopause	0.2	0.2	1.9	0.1	-0.4	0.0	0.5	-0.1	0.1	-0.4	0.3	0.1	0.6	0.2	1.4	0.2	-0.3	0.2	0.1	0.2
Diabetes (self-reported)	0.2	0.2	1.1	-0.0	-0.9	-0.1	0.4	-0.2	0.7	0.2	-0.1	-0.4	0.1	-0.2	0.9	-0.3	-1.0	-0.3	-0.5	-0.2
Weight	0.2	0.8	5.2	0.7	1.1	0.0	1.0	0.4	2.3	-2.1	0.5	-0.1	0.1	0.2	1.1	0.2	-0.4	0.2	0.1	0.3
Arm fat percentage (right)	0.2	0.8	3.5	1.2	-0.2	0.8	0.9	0.9	1.4	-1.9	1.0	0.5	0.2	0.8	0.5	0.8	-0.1	0.8	0.8	0.9
Time employed in main current job	0.2	0.3	0.6	0.6	0.4	0.6	-0.4	0.2	0.6	0.8	0.5	0.5	0.4	0.4	-0.8	0.4	-0.5	0.4	0.4	0.5
Alcohol intake versus 10 years previously	0.2	0.3	1.3	-0.3	-1.0	-0.6	0.1	-0.6	-0.0	-1.2	-0.2	-0.7	-0.9	-0.6	-0.2	-0.5	-0.5	-0.5	-0.4	-0.3
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	2.4	-0.1	-0.6	0.0	0.7	-0.2	0.3	-1.5	-0.5	0.4	-0.2	-0.2	0.4	-0.2	0.2	-0.2	0.1	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.7	0.3	0.2	0.1	1.3	-0.1	-0.1	0.5	0.0	0.1	-0.1	0.1	1.2	-0.0	1.0	0.0	0.1	0.0
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.5	-0.2	-0.3	0.4	0.2	-0.2	0.3	-0.5	-0.6	0.4	-1.0	-0.3	-0.5	-0.3	1.2	-0.3	-0.0	-0.4
Headache pain in last month	0.2	0.4	1.6	0.5	0.8	0.4	1.3	0.3	0.4	-0.7	0.4	0.6	0.4	0.3	0.8	0.4	0.8	0.4	0.5	0.4
Glaucoma (self-reported)	0.2	0.2	1.3	0.3	-0.8	0.6	0.1	0.2	0.1	1.1	0.2	0.5	0.5	0.6	0.5	0.3	0.1	0.3	0.4	0.2
Gout (self-reported)	0.2	0.2	1.2	-0.2	1.1	-0.7	0.2	0.2	-0.2	-0.7	0.1	-0.6	-0.2	-0.1	-0.0	-0.3	-0.7	-0.3	-0.3	-0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.3	2.2	0.1	-0.0	0.2	-0.8	0.1	-0.7	1.1	-0.2	-0.0	-0.6	-0.1	-1.5	0.1	0.2	0.1	0.0	-0.0
Chronic bronchitis/emphysema (mother)	0.2	0.2	1.4	0.7	0.4	0.5	1.2	0.2	0.4	0.2	0.3	0.4	0.1	0.4	0.7	0.3	0.5	0.3	0.4	0.3
Body fat percentage	0.2	0.9	6.8	0.8	-0.2	0.4	1.3	0.6	1.2	-2.6	0.8	0.2	0.3	0.6	0.9	0.5	-0.4	0.5	0.5	0.7
Leg fat percentage (right)	0.2	0.8	7.6	0.5	-0.5	-0.0	1.5	0.3	0.8	-2.8	0.5	-0.1	0.1	0.3	1.0	0.2	-0.7	0.2	0.2	0.3
Arm fat-free mass (right)	0.2	1.1	2.4	-0.5	1.5	-1.3	0.2	-0.8	1.2	-1.5	-0.7	-1.5	-1.0	-1.1	0.4	-1.1	-0.8	-1.1	-1.3	-1.0
Exposure to tobacco smoke outside home	0.2	0.3	1.1	-0.3	-0.9	-0.2	0.5	-0.7	-0.7	-1.0	-0.4	0.0	-0.8	-0.3	-0.3	-0.4	1.0	-0.4	-0.1	-0.3
Comparative body size at age 10	0.2	0.6	2.0	-0.6	0.3	-0.8	1.1	-0.7	0.4	-1.4	-0.3	-1.1	0.1	-0.8	-0.6	-0.5	-1.4	-0.5	-0.9	-0.4
Qualifications: College or University degree	0.2	0.6	4.0	0.2	1.7	0.3	1.4	0.5	0.6	0.1	0.2	0.3	0.8	-0.2	2.0	0.3	0.3	0.3	0.0	0.2
Medication: Allopurinol	0.2	0.3	2.2	-0.2	1.5	-0.5	-0.2	0.2	-0.2	-1.0	0.1	-0.3	-0.2	0.1	0.2	-0.3	-0.8	-0.2	-0.0	-0.1
Mean time to correctly identify matches	0.2	0.4	3.7	0.2	-0.4	-0.1	-0.1	-0.1	-0.9	1.0	0.1	-0.3	-1.2	0.0	-1.9	-0.0	0.6	-0.0	0.1	0.1
Whole body fat mass	0.2	1.0	5.4	1.0	0.5	0.5	1.2	0.7	2.0	-2.3	0.9	0.3	0.3	0.7	1.1	0.6	-0.2	0.6	0.6	0.7
Leg fat mass (right)	0.2	0.7	7.3	0.3	-0.1	-0.3	0.9	0.0	1.2	-2.7	0.2	-0.4	-0.2	0.0	0.6	-0.1	-0.8	-0.1	-0.1	-0.1
Arm predicted mass (right)	0.2	1.1	2.8	-0.5	1.7	-1.3	0.4	-0.8	1.3	-1.5	-0.6	-1.5	-0.8	-1.0	0.6	-1.1	-0.9	-1.1	-1.2	-1.0
Comparative height size at age 10	0.2	1.1	11.5	-0.1	3.4	0.0	2.0	0.1	1.4	-0.6	-0.0	0.2	-0.0	-0.1	0.4	-0.1	0.6	-0.1	0.0	-0.1
Age at last live birth	0.2	0.2	0.5	0.7	-0.2	0.5	-0.3	0.4	0.4	0.6	0.7	0.1	0.6	0.4	0.2	0.6	0.4	0.6	0.2	0.6
Supplements: Vitamin C	0.2	0.3	1.2	-0.7	1.1	-0.3	0.2	-0.7	-0.2	1.1	-0.3	-0.3	0.1	-0.3	-0.1	-0.5	-0.2	-0.5	-0.4	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	1.7	0.3	0.8	-0.1	-1.3	0.4	0.0	-0.3	0.2	-0.3	0.4	0.1	0.1	0.2	-0.1	0.2	-0.1	0.1
Smoking status: Previous	0.2	0.2	1.9	0.3	0.7	0.7	0.5	0.3	0.4	0.4	-0.3	0.5	-0.3	0.1	-0.1	0.1	1.4	0.1	0.2	-0.0
Arm fat percentage (left)	0.2	0.6	5.1	0.9	-0.5	0.4	0.8	0.6	1.1	-2.3	0.7	0.0	-0.1	0.5	0.3	0.5	-0.7	0.5	0.4	0.6
Long-standing illness, disability or infirmity	0.2	0.3	2.1	0.3	-1.5	-0.2	-0.3	0.1	0.3	-0.8	0.1	-0.3	0.4	0.0	0.9	0.0	-0.8	0.0	-0.2	-0.0
Diabetes diagnosed by doctor	0.2	0.3	1.9	0.2	-0.6	0.2	0.8	-0.2	1.1	0.4	0.2	-0.1	0.6	0.2	1.4	-0.1	-0.9	-0.1	-0.2	-0.0
Breast cancer (self-reported)	0.2	0.2	0.7	0.1	-0.6	-0.6	0.6	0.1	-0.3	-0.2	0.3	-0.7	0.1	-0.2	0.7	0.1	-0.9	0.1	-0.3	-0.0
Smoking status: Current	0.2	0.3	2.0	0.3	-0.0	0.3	1.1	0.2	-0.1	0.0	0.4	0.4	0.1	0.2	1.4	0.2	0.9	0.2	0.3	0.3
Average weekly champagne plus white wine intake	0.2	0.3	0.7	-0.6	0.6	-0.6	-0.9	-0.2	-0.2	-0.3	-0.5	-0.7	-0.1	-0.5	0.3	-0.5	-0.1	-0.5	-0.7	-0.6
Guilty feelings	0.2	0.3	1.7	-0.3	-1.3	-0.6	-0.7	-0.6	-0.5	-1.0	-0.4	-0.5	-0.6	-0.5	0.2	-0.3	-0.2	-0.3	-0.4	-0.5
Ever taken oral contraceptive pill	0.2	0.2	0.7	0.7	0.4	0.2	0.8	0.7	0.7	0.5	0.4	0.1	-0.3	0.5	-0.0	0.5	0.3	0.5	0.4	0.5
Leg fat percentage (left)	0.2	0.8	6.2	0.6	-0.5	-0.0	1.7	0.3	0.9	-2.5	0.5	-0.2	0.2	0.3	1.2	0.3	-0.6	0.3	0.1	0.3
Arm fat-free mass (left)	0.2	0.8	4.3	-0.1	2.1	-0.8	0.6	-0.4	1.6	-1.1	-0.3	-1.0	-0.7	-0.7	0.6	-0.7	-0.2	-0.7	-0.8	-0.6
Average weekly beer plus cider intake	0.2	0.2	0.8	-0.1	-0.5	-0.3	-0.8	-0.4	-0.7	-0.6	-0.4	-0.3	-0.9	-0.2	-0.9	-0.4	-0.3	-0.3	-0.1	-0.3
Risk taking	0.2	0.3	1.8	-0.1	0.4	-0.5	-1.4	0.3	-0.2	0.7	-0.2	-0.9	-0.1	-0.3	0.2	-0.1	-0.2	-0.1	-0.6	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	2.3	0.4	0.7	0.6	-0.3	0.3	0.9	0.0	0.2	0.4	-0.1	0.5	-1.5	0.5	0.2	0.5	0.4	0.4
Alcohol drinker status: Previous	0.2	0.2	1.5	0.1	0.5	0.6	-0.2	-0.0	0.7	0.5	0.2	0.6	0.0	0.3	0.2	0.2	1.2	0.2	0.4	0.2
Leg fat mass (left)	0.2	0.7	6.9	0.4	-0.0	-0.3	1.1	0.1	1.2	-2.6	0.2	-0.4	-0.1	0.0	0.8	-0.1	-0.8	-0.1	-0.1	-0.0
Bipolar Disorder (2018)	0.1	0.1	0.4	-0.6	0.2	-0.1	-0.6	-0.6	-0.6	0.3	-0.3	0.0	-0.4	-0.0	-0.4	-0.4	0.2	-0.4	-0.1	0.0
Major Depression (MDD)	0.1	0.2	1.8	-0.1	-0.3	-0.1	-1.4	-0.2	0.0	-0.8	-0.2	-0.3	0.4	-0.1	0.2	0.0	0.0	-0.0	-0.3	0.0
Crohns Disease (2012)	0.1	0.2	1.2	0.1	0.3	0.4	0.7	0.3	0.3	-1.1	0.2	0.4	-0.1	0.1	-0.4	0.1	0.6	0.1	0.3	0.0
Blood Platelet Count	0.1	0.9	6.0	-0.5	-2.5	-0.4	-0.9	-0.8	-2.0	0.6	-0.6	-0.5	0.3	-0.6	0.7	-0.5	-0.5	-0.5	-0.7	-0.6
BMI	0.1	0.8	5.6	-0.2	-0.6	-0.6	-0.1	-0.6	1.1	-2.4	-0.6	-1.0	-1.0	-0.6	0.1	-0.7	-0.6	-0.7	-0.8	-0.7
Waist Hip Ratio (WHR)	0.1	0.4	3.5	-0.4	-0.2	0.5	0.8	0.0	-1.9	1.1	-0.6	0.3	-0.5	-0.1	-0.3	-0.2	-0.2	-0.2	-0.1	-0.2
Smoking Status	0.1	0.3	1.8	-0.1	0.9	0.2	0.8	0.1	-0.1	0.4	-0.4	0.2	-0.8	-0.1	0.3	-0.2	1.3	-0.2	0.0	-0.3
Tanning	0.1	1.6	4.2	-1.0	-0.6	-1.3	-1.9	-1.0	-1.1	-1.1	-1.2	-1.5	-1.6	-1.3	-2.0	-1.1	-0.7	-1.1	-1.3	-1.1
Sensitivity / hurt feelings	0.1	0.1	0.6	-0.3	-0.8	0.4	-0.3	-0.2	0.5	0.1	-0.2	0.5	-0.1	-0.0	0.4	0.1	0.2	0.0	0.2	-0.0
Medication: Metformin	0.1	0.2	1.6	0.1	-0.4	0.0	0.4	0.1	0.6	1.3	0.1	-0.1	0.2	0.1	0.4	-0.0	-0.1	-0.0	-0.1	-0.1
Leg fat-free mass (left)	0.1	0.5	4.5	0.6	1.1	-0.2	-0.0	0.3	2.1	-1.5	0.4	-0.4	-0.1	0.0	0.5	0.0	-0.4	0.0	-0.2	0.1
Townsend deprivation index at recruitment	0.1	0.1	1.4	0.2	-0.0	0.3	0.2	-0.2	0.2	-0.0	0.0	0.3	-0.7	-0.1	-0.3	-0.0	1.2	-0.0	0.2	-0.1
Maternal smoking around birth	0.1	0.2	0.9	-0.5	-0.3	0.1	0.0	-0.7	0.2	-0.6	-0.6	0.1	-0.2	-0.1	1.0	-0.6	-0.1	-0.6	-0.3	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	1.1	-0.1	-0.5	0.1	1.0	-0.3	-0.7	0.4	-0.4	0.2	-0.5	-0.4	0.6	-0.3	-0.0	-0.3	-0.1	-0.3
Taking other prescription medications	0.1	0.1	0.8	0.5	-0.1	0.1	-0.9	0.4	-0.2	-0.5	0.1	0.2	0.0	0.1	0.8	0.1	0.3	0.1	0.2	0.1
High blood pressure	0.1	0.4	2.3	0.5	-0.4	0.3	-1.5	0.3	0.6	-0.8	0.6	0.1	0.2	0.6	0.2	0.6	0.1	0.6	0.4	0.7
Stomach or abdominal pain in last month	0.1	0.1	0.3	-0.0	0.4	-0.1	0.4	0.1	-0.4	0.4	0.4	0.0	-0.1	0.3	-0.6	0.1	-0.2	0.1	0.3	0.2
Medication: Levothyroxine sodium	0.1	0.2	1.8	0.2	-0.0	0.3	0.2	-0.1	-0.2	1.3	-0.3	0.0	-0.9	-0.1	-0.5	-0.2	1.0	-0.2	-0.1	-0.2
High blood pressure (mother)	0.1	0.1	0.6	-0.1	0.3	-0.1	0.5	0.0	0.1	-0.8	0.0	-0.4	0.3	-0.2	-0.4	-0.0	-0.4	-0.0	-0.3	-0.1
Leg predicted mass (left)	0.1	0.5	4.4	0.6	1.1	-0.2	0.0	0.3	2.1	-1.6	0.3	-0.5	-0.1	-0.0	0.5	-0.0	-0.5	-0.0	-0.2	0.1
Waist circumference	0.1	0.5	2.3	0.8	0.5	0.5	1.1	0.4	1.3	-1.5	0.3	0.3	0.0	0.4	1.1	0.3	-0.0	0.3	0.3	0.3
Number of incorrect matches in round	0.1	0.1	0.4	-0.1	0.6	0.0	-0.6	0.0	-0.0	-0.5	-0.1	0.3	0.0	0.1	-0.7	-0.0	-0.0	-0.0	0.2	-0.1
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	2.2	0.2	0.2	0.2	0.9	0.1	-0.0	0.2	0.2	0.4	0.7	0.1	1.5	0.1	-0.1	0.1	0.2	0.1
Mouth/teeth dental problems	0.1	0.2	1.0	-0.1	-0.2	-0.7	-0.3	0.0	-0.4	-0.1	0.2	-0.5	0.6	-0.3	0.2	-0.0	-1.0	-0.0	-0.3	-0.0
Neuroticism score	0.1	0.2	0.9	0.1	-0.3	0.5	0.0	-0.1	-0.2	0.2	0.3	0.8	0.6	0.4	1.0	0.3	0.3	0.4	0.6	0.3
Trunk fat-free mass	0.1	0.8	7.7	0.5	2.8	-0.3	0.6	0.2	2.1	-0.3	0.2	-0.4	-0.1	-0.1	0.7	-0.1	0.5	-0.1	-0.2	-0.1
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.9	-0.0	-0.4	-0.1	0.9	-0.3	-0.4	-0.6	-0.1	-0.2	-0.4	-0.1	-0.4	-0.2	-0.1	-0.2	-0.1	-0.2
Falls in the last year	0.1	0.2	1.3	-0.1	0.9	-0.2	-0.1	0.3	-0.1	1.1	-0.2	-0.2	-0.5	-0.2	0.0	-0.0	0.5	-0.1	-0.2	-0.1
Arm fat mass (right)	0.1	0.5	4.9	0.6	0.2	0.0	0.9	0.3	1.4	-2.2	0.4	-0.2	-0.2	0.2	0.4	0.2	-0.5	0.2	0.1	0.2
Trunk predicted mass	0.1	0.8	7.8	0.5	2.8	-0.3	0.6	0.3	2.1	-0.3	0.3	-0.4	-0.1	-0.0	0.7	-0.0	0.5	-0.1	-0.1	0.0
Tense / ‘highly strung’	0.1	0.1	0.7	-0.3	-0.1	0.4	-0.2	-0.1	-0.1	0.1	-0.1	0.6	0.8	0.2	0.8	0.0	-0.3	0.1	0.3	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.7	-0.0	-0.5	-0.1	0.1	-0.2	-0.2	0.6	-0.4	-0.3	-0.8	-0.3	-0.3	-0.4	0.3	-0.4	-0.4	-0.3
Wheeze or whistling in the chest in last year	0.1	0.1	0.9	-0.6	0.1	0.2	-0.3	-0.3	-0.1	0.4	-0.5	0.1	-0.2	-0.1	-0.1	-0.3	-0.9	-0.3	-0.2	-0.4
Age at first live birth	0.1	0.2	0.6	-0.3	-0.8	-0.4	-0.4	-0.5	-0.4	0.1	-0.2	-0.8	-0.3	-0.4	-0.3	-0.3	-0.2	-0.3	-0.7	-0.2
Neck or shoulder pain in last month	0.1	0.1	0.5	0.1	0.1	0.4	0.2	0.2	0.6	-0.3	0.3	0.4	0.7	0.5	0.7	0.1	-0.2	0.1	0.3	0.2
Pulse rate, automated reading	0.1	0.4	2.5	0.1	0.2	0.9	0.3	0.4	0.3	0.2	-0.1	1.1	0.1	0.4	0.8	0.1	1.6	0.1	0.6	0.1
Suffer from ‘nerves’	0.1	0.1	0.5	-0.3	0.1	0.1	-0.3	-0.3	-0.7	0.7	-0.2	0.3	0.1	0.2	0.6	-0.3	0.3	-0.3	0.1	-0.3
Qualifications: NVQ or HND or HNC or equivalent	0.1	0.1	0.6	0.8	-0.1	0.2	0.3	0.5	0.4	-0.2	0.5	0.0	0.3	0.5	-0.1	0.5	0.2	0.5	0.3	0.5
Knee pain experienced in last month	0.1	0.1	0.5	0.3	0.7	0.3	0.2	0.4	0.6	-0.0	0.0	0.0	0.3	0.1	0.7	0.2	0.3	0.2	-0.0	0.2
Hypertension (Self-reported)	0.1	0.3	2.2	0.4	-0.5	0.2	-1.5	0.4	0.3	-0.8	0.5	-0.0	0.0	0.6	-0.0	0.5	0.3	0.5	0.3	0.6
Whole body fat-free mass	0.1	0.6	4.3	0.4	2.1	-0.4	0.3	0.1	2.0	-0.8	0.1	-0.6	-0.3	-0.2	0.7	-0.2	0.0	-0.2	-0.4	-0.1
Leg fat-free mass (right)	0.1	0.5	3.5	0.4	1.0	-0.4	-0.1	0.1	1.9	-1.4	0.2	-0.7	-0.2	-0.2	0.5	-0.2	-0.6	-0.2	-0.4	-0.1
Average weekly red wine intake	0.1	0.2	1.6	0.4	-0.2	-0.0	1.3	0.5	0.3	0.3	0.2	0.0	0.6	0.1	0.8	0.3	-0.3	0.3	0.1	0.1
Osteoarthritis (self-reported)	0.1	0.2	1.0	-0.3	0.6	0.0	0.1	-0.2	0.1	0.7	-0.5	-0.1	-0.0	-0.2	1.0	-0.3	0.2	-0.3	-0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.1	0.4	0.5	0.4	-1.0	0.8	0.8	0.3	0.3	0.4	0.8	0.4	0.5	0.5	-0.4	0.5	0.4	0.3
Whole body water mass	0.1	0.7	4.8	0.4	2.2	-0.4	0.4	0.1	2.0	-0.8	0.1	-0.6	-0.3	-0.2	0.7	-0.3	0.1	-0.3	-0.4	-0.2
Leg predicted mass (right)	0.1	0.5	3.6	0.5	1.1	-0.4	0.0	0.2	1.9	-1.3	0.3	-0.7	-0.2	-0.2	0.5	-0.1	-0.5	-0.1	-0.4	-0.0
Arm fat mass (left)	0.1	0.5	5.3	0.4	0.1	-0.2	0.8	0.1	1.2	-2.3	0.2	-0.5	-0.4	-0.0	0.5	-0.1	-0.9	-0.1	-0.2	0.0
Number of self-reported non-cancer illnesses	0.1	0.2	1.1	0.3	0.4	0.2	0.9	0.3	0.0	0.4	-0.1	-0.0	-0.2	0.2	1.0	0.0	0.3	-0.0	-0.1	0.0
Miserableness	0.1	0.1	0.4	0.1	0.3	0.5	0.6	0.1	0.3	0.4	0.1	0.6	0.5	0.2	0.2	0.3	0.4	0.3	0.3	0.2
Medication: Bendroflumethiazide	0.1	0.2	1.4	-0.2	0.1	0.3	-0.6	-0.1	0.1	0.5	-0.3	0.5	-0.1	0.1	0.8	-0.2	1.2	-0.2	0.2	-0.2
Basal metabolic rate	0.1	0.6	4.2	0.4	1.9	-0.4	0.5	0.1	2.0	-1.2	0.1	-0.6	-0.3	-0.2	0.7	-0.3	-0.2	-0.3	-0.4	-0.2
Age started oral contraceptive pill	0.1	0.1	0.2	0.4	-0.5	-0.1	0.1	0.4	-0.1	-0.4	0.2	-0.0	-0.2	0.2	0.1	0.3	0.3	0.3	0.3	0.1
Myopia	0.1	0.1	0.6	0.0	-0.0	-0.3	-0.2	-0.2	-0.3	0.8	-0.4	-0.3	-0.4	-0.4	-0.2	-0.4	-0.6	-0.4	-0.4	-0.4
Vascular/heart problems diagnosed by doctor	0.1	0.3	2.2	0.0	1.0	0.2	1.5	0.3	-0.3	1.1	-0.1	0.4	0.2	-0.1	-0.1	-0.1	0.4	-0.1	0.1	-0.2
Arm predicted mass (left)	0.1	0.7	4.8	0.1	2.2	-0.6	0.7	-0.2	1.7	-0.9	-0.1	-0.7	-0.4	-0.4	0.8	-0.5	-0.2	-0.5	-0.6	-0.4
Body Mass Index (BMI) (2010)	0.0	0.1	0.3	0.1	0.1	-0.3	-0.3	0.2	0.1	-0.6	-0.0	-0.4	-0.1	-0.0	-0.5	0.0	-0.2	0.0	-0.1	0.0
Overall health rating	0.0	0.1	0.6	0.0	0.5	0.1	0.8	0.3	-0.1	-0.1	0.0	0.1	-0.2	0.1	0.4	-0.0	-0.7	0.0	0.1	-0.0
Back pain experienced in last month	0.0	0.1	0.3	0.1	0.5	-0.2	0.2	0.2	0.1	-0.4	0.2	-0.2	-0.1	-0.0	0.0	0.1	-0.5	0.1	0.0	-0.0

Hub : Genes

MMAA

Models

Trait associations