[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (right) : ← →

chr4:85,698,680-89,692,911

Best TWAS P=1.5e-12 · Best GWAS P=5.7e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ARHGAP24 0.24 0.13 enet 8 0.14 2.2e-08 5.1 5.8 8.6e-09 0.03 0.01 0.99 FALSE
2 GTEx Artery Aorta RP13-514E23.2 0.26 0.09 lasso 6 0.10 2.2e-06 5.5 5.6 2.4e-08 0.04 0.01 0.99 FALSE
3 GTEx Artery Tibial ARHGAP24 0.26 0.19 enet 14 0.21 2.7e-16 5.5 5.5 4.4e-08 0.03 0.00 1.00 FALSE
4 GTEx Artery Tibial RP13-514E23.2 0.22 0.16 enet 10 0.18 1.2e-13 5.5 5.9 4.4e-09 0.03 0.00 1.00 TRUE
5 GTEx Nerve Tibial SPP1 0.15 0.08 lasso 3 0.08 2.4e-06 6.9 7.1 1.5e-12 0.99 0.00 1.00 TRUE
6 METSIM Adipose HSD17B13 0.20 0.10 bslmm 416 0.12 7.3e-18 -4.6 5.4 6.5e-08 -0.08 0.89 0.11 TRUE
7 ROSMAP Brain Pre-frontal Cortex PKD2 0.11 0.09 lasso 13 0.11 3.3e-14 3.9 5.7 1.0e-08 0.39 0.97 0.03 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma IBSP 0.05 0.05 lasso 6 0.07 1.2e-13 4.4 -6.1 1.1e-09 -0.12 0.97 0.03 TRUE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma IBSP 0.10 0.05 enet 8 0.09 1.5e-10 1.7 -5.3 1.3e-07 -0.23 0.69 0.31 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma IBSP 0.06 0.01 blup 78 0.03 8.2e-05 5.1 -5.5 4.6e-08 -0.25 0.15 0.25 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IBSP 0.03 0.01 blup 78 0.03 2.8e-04 -5.1 -6.4 1.6e-10 -0.35 0.08 0.13 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma IBSP 0.16 0.05 blup 76 0.08 3.6e-06 -5.3 -6.4 1.7e-10 -0.26 0.76 0.21 FALSE