Best TWAS P=2.27e-10 · Best GWAS P=1.91e-15 conditioned to 1.62e-11
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | HIBADH | 0.31 | 0.13 | enet | 20 | 0.11 | 1.2e-03 | -5.5 | 5.9 | 3.8e-09 | 0.28 | 0.14 | 0.52 | FALSE |
| 2 | GTEx | Esophagus Mucosa | HIBADH | 0.13 | 0.09 | lasso | 4 | 0.10 | 1.8e-07 | -5.5 | 5.2 | 2.1e-07 | 0.11 | 0.99 | 0.00 | FALSE |
| 3 | GTEx | Testis | TAX1BP1 | 0.31 | 0.28 | enet | 15 | 0.28 | 9.0e-13 | -5.5 | -5.4 | 8.4e-08 | -0.08 | 1.00 | 0.00 | FALSE |
| 4 | GTEx | Testis | AC004549.6 | 0.18 | 0.02 | lasso | 6 | 0.02 | 4.0e-02 | -5.7 | -6.3 | 2.3e-10 | -0.22 | 0.24 | 0.05 | TRUE |