[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (right) : ← →

chr6:151,118,271-153,120,904

Best TWAS P=5.35e-83 · Best GWAS P=1.79e-69 conditioned to 0.00143

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ESR1	0.19	0.10	enet	36	0.10	2.2e-12	11.5	-8.9	5.8e-19	-0.03	1.00	0.00	TRUE
2	METSIM	Adipose	CCDC170	0.14	0.02	blup	621	0.07	6.1e-11	-2.0	-9.3	1.2e-20	0.35	0.99	0.00	TRUE
3	ROSMAP	Brain Pre-frontal Cortex	CCDC170	0.20	0.06	lasso	10	0.19	7.2e-24	-5.3	-5.2	2.2e-07	0.53	0.11	0.89	FALSE
4	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C6orf97	0.05	0.00	blup	133	0.03	1.3e-03	-17.6	-17.5	1.3e-68	0.80	0.01	0.87	TRUE
5	The Cancer Genome Atlas	Breast Invasive Carcinoma	C6orf97	0.01	0.01	enet	7	0.01	5.3e-03	-8.8	-16.7	2.4e-62	0.82	0.01	0.94	TRUE
6	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C6orf97	0.08	0.02	blup	133	0.07	6.2e-08	-9.5	-13.2	7.6e-40	0.68	0.02	0.98	TRUE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf97	0.06	0.05	lasso	3	0.08	6.9e-09	-10.4	-12.4	2.3e-35	0.58	0.22	0.76	FALSE
8	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C6orf97	0.18	0.06	lasso	4	0.05	1.1e-03	-5.3	-6.8	8.4e-12	0.49	0.33	0.32	FALSE
9	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf97	0.08	0.04	blup	133	0.09	1.2e-10	-17.6	-14.8	9.1e-50	0.78	0.00	1.00	FALSE
10	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf97	0.07	0.03	lasso	5	0.05	1.7e-06	-5.3	-12.2	2.3e-34	0.71	0.01	0.97	FALSE
11	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf97	0.14	0.01	blup	133	0.08	5.2e-06	-17.6	-12.2	3.2e-34	0.74	0.00	0.94	FALSE
12	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C6orf97	0.23	0.10	lasso	11	0.11	1.8e-05	-17.6	-19.3	5.3e-83	0.87	0.00	0.99	TRUE
13	The Cancer Genome Atlas	Prostate Adenocarcinoma	C6orf97	0.10	0.05	blup	133	0.06	2.6e-07	-17.6	-10.6	4.9e-26	0.72	0.00	1.00	TRUE
14	The Cancer Genome Atlas	Stomach Adenocarcinoma	C6orf97	0.13	0.02	blup	133	0.05	2.8e-04	-9.5	-11.4	3.1e-30	0.63	0.01	0.90	TRUE
15	The Cancer Genome Atlas	Testicular Germ Cell Tumors	RMND1	0.19	0.06	blup	58	0.10	1.6e-04	-4.2	5.6	2.2e-08	0.10	0.14	0.20	FALSE
16	The Cancer Genome Atlas	Thyroid Carcinoma	C6orf97	0.08	0.02	lasso	4	0.06	3.4e-06	-16.5	-14.7	8.7e-49	0.85	0.01	0.98	TRUE