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chr10:80,443,273-82,223,767

Best TWAS P=1.64e-13 · Best GWAS P=2.31e-10 conditioned to 0.822

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ZCCHC24	0.12	0.01	lasso	6	0.03	3.4e-03	3.4	6.7	2.5e-11	0.52	0.04	0.85	TRUE
2	GTEx	Adipose Visceral Omentum	BEND3P3	0.27	0.13	lasso	10	0.13	3.0e-07	6.0	-6.3	3.6e-10	-0.90	0.01	0.99	FALSE
3	GTEx	Artery Aorta	BEND3P3	0.19	0.05	enet	22	0.09	7.5e-06	4.5	-5.5	4.3e-08	-0.79	0.05	0.94	FALSE
4	GTEx	Artery Aorta	RP11-119F19.2	0.22	0.16	lasso	9	0.18	2.7e-10	5.9	-5.8	8.9e-09	-0.87	0.03	0.97	FALSE
5	GTEx	Artery Coronary	RP11-119F19.2	0.24	0.14	lasso	6	0.12	7.0e-05	6.3	-6.4	1.9e-10	-0.97	0.01	0.98	FALSE
6	GTEx	Artery Tibial	BEND3P3	0.22	0.07	enet	14	0.10	5.8e-08	5.9	-5.3	1.2e-07	-0.77	0.02	0.98	FALSE
7	GTEx	Artery Tibial	RP11-506M13.3	0.12	0.06	lasso	5	0.04	3.2e-04	5.9	-5.8	6.1e-09	-0.85	0.02	0.96	FALSE
8	GTEx	Esophagus Mucosa	RP11-119F19.2	0.20	0.10	lasso	5	0.18	2.1e-12	5.9	-5.1	2.7e-07	-0.82	0.04	0.96	FALSE
9	GTEx	Esophagus Muscularis	BEND3P3	0.17	0.13	lasso	6	0.13	4.4e-08	4.5	-5.5	4.9e-08	-0.79	0.11	0.89	FALSE
10	GTEx	Heart Atrial Appendage	RP11-119F19.2	0.18	0.03	lasso	7	0.05	2.5e-03	5.9	-5.7	1.5e-08	-0.79	0.02	0.89	FALSE
11	GTEx	Liver	RP11-119F19.2	0.24	0.05	lasso	6	0.02	7.5e-02	5.8	5.3	1.2e-07	0.47	0.04	0.45	FALSE
12	GTEx	Lung	BEND3P3	0.16	0.06	enet	12	0.09	2.7e-07	4.3	-6.3	3.0e-10	-0.75	0.03	0.97	FALSE
13	GTEx	Lung	RP11-119F19.2	0.24	0.09	lasso	12	0.18	1.5e-13	5.8	-5.2	2.1e-07	-0.63	0.04	0.96	FALSE
14	GTEx	Nerve Tibial	RP11-506M13.3	0.08	0.04	lasso	3	0.05	3.3e-04	2.2	-5.7	1.5e-08	-0.70	0.05	0.88	FALSE
15	GTEx	Thyroid	BEND3P3	0.20	0.12	lasso	4	0.17	4.1e-13	6.0	-5.9	3.4e-09	-0.82	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ZCCHC24	0.06	0.00	blup	89	0.01	6.2e-02	4.9	6.2	6.1e-10	0.63	0.01	0.22	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	SFTPA2	0.06	0.03	enet	12	0.04	2.1e-09	4.5	-6.8	9.3e-12	-0.83	0.19	0.81	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZCCHC24	0.03	0.01	blup	89	0.02	2.0e-04	4.9	5.9	4.5e-09	0.67	0.15	0.64	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	SFTPA2	0.14	0.08	enet	8	0.10	7.6e-12	5.8	-7.4	1.6e-13	-0.77	0.02	0.98	TRUE