[Hub]/) : Traits : Hand grip strength (right) :

chr10:80,443,273-82,223,767

Best TWAS P=1.64e-13 · Best GWAS P=2.31e-10 conditioned to 0.822

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous ZCCHC24 0.12 0.01 lasso 6 0.03 3.4e-03 3.4 6.7 2.5e-11 0.52 0.04 0.85 TRUE
2 GTEx Adipose Visceral Omentum BEND3P3 0.27 0.13 lasso 10 0.13 3.0e-07 6.0 -6.3 3.6e-10 -0.90 0.01 0.99 FALSE
3 GTEx Artery Aorta BEND3P3 0.19 0.05 enet 22 0.09 7.5e-06 4.5 -5.5 4.3e-08 -0.79 0.05 0.94 FALSE
4 GTEx Artery Aorta RP11-119F19.2 0.22 0.16 lasso 9 0.18 2.7e-10 5.9 -5.8 8.9e-09 -0.87 0.03 0.97 FALSE
5 GTEx Artery Coronary RP11-119F19.2 0.24 0.14 lasso 6 0.12 7.0e-05 6.3 -6.4 1.9e-10 -0.97 0.01 0.98 FALSE
6 GTEx Artery Tibial BEND3P3 0.22 0.07 enet 14 0.10 5.8e-08 5.9 -5.3 1.2e-07 -0.77 0.02 0.98 FALSE
7 GTEx Artery Tibial RP11-506M13.3 0.12 0.06 lasso 5 0.04 3.2e-04 5.9 -5.8 6.1e-09 -0.85 0.02 0.96 FALSE
8 GTEx Esophagus Mucosa RP11-119F19.2 0.20 0.10 lasso 5 0.18 2.1e-12 5.9 -5.1 2.7e-07 -0.82 0.04 0.96 FALSE
9 GTEx Esophagus Muscularis BEND3P3 0.17 0.13 lasso 6 0.13 4.4e-08 4.5 -5.5 4.9e-08 -0.79 0.11 0.89 FALSE
10 GTEx Heart Atrial Appendage RP11-119F19.2 0.18 0.03 lasso 7 0.05 2.5e-03 5.9 -5.7 1.5e-08 -0.79 0.02 0.89 FALSE
11 GTEx Liver RP11-119F19.2 0.24 0.05 lasso 6 0.02 7.5e-02 5.8 5.3 1.2e-07 0.47 0.04 0.45 FALSE
12 GTEx Lung BEND3P3 0.16 0.06 enet 12 0.09 2.7e-07 4.3 -6.3 3.0e-10 -0.75 0.03 0.97 FALSE
13 GTEx Lung RP11-119F19.2 0.24 0.09 lasso 12 0.18 1.5e-13 5.8 -5.2 2.1e-07 -0.63 0.04 0.96 FALSE
14 GTEx Nerve Tibial RP11-506M13.3 0.08 0.04 lasso 3 0.05 3.3e-04 2.2 -5.7 1.5e-08 -0.70 0.05 0.88 FALSE
15 GTEx Thyroid BEND3P3 0.20 0.12 lasso 4 0.17 4.1e-13 6.0 -5.9 3.4e-09 -0.82 0.02 0.98 FALSE
16 The Cancer Genome Atlas Bladder Urothelial Carcinoma ZCCHC24 0.06 0.00 blup 89 0.01 6.2e-02 4.9 6.2 6.1e-10 0.63 0.01 0.22 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma SFTPA2 0.06 0.03 enet 12 0.04 2.1e-09 4.5 -6.8 9.3e-12 -0.83 0.19 0.81 FALSE
18 The Cancer Genome Atlas Breast Invasive Carcinoma ZCCHC24 0.03 0.01 blup 89 0.02 2.0e-04 4.9 5.9 4.5e-09 0.67 0.15 0.64 FALSE
19 The Cancer Genome Atlas Brain Lower Grade Glioma SFTPA2 0.14 0.08 enet 8 0.10 7.6e-12 5.8 -7.4 1.6e-13 -0.77 0.02 0.98 TRUE