[Hub]/) : Traits : Waist circumference :

chr19:17,512,412-20,352,206

Best TWAS P=1.52e-14 · Best GWAS P=4.25e-18 conditioned to 0.173

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KIAA1683 0.09 0.06 enet 14 0.10 6.6e-12 -3.49 6.0 1.7e-09 0.60 0.68 0.32 FALSE
2 GTEx Adipose Subcutaneous AC005253.4 0.11 0.06 enet 23 0.04 1.6e-04 -0.48 5.6 1.8e-08 0.46 0.24 0.38 FALSE
3 GTEx Colon Transverse SSBP4 0.18 0.01 enet 21 0.00 3.6e-01 5.12 -5.5 4.0e-08 -0.57 0.06 0.25 FALSE
4 GTEx Colon Transverse KIAA1683 0.15 0.02 lasso 3 0.02 3.3e-02 -4.04 6.5 8.7e-11 0.55 0.28 0.28 FALSE
5 GTEx Nerve Tibial KIAA1683 0.25 0.22 lasso 9 0.28 5.2e-20 7.68 6.0 1.4e-09 0.52 0.80 0.20 FALSE
6 GTEx Pancreas AC007192.6 0.19 0.00 enet 28 0.01 1.3e-01 7.77 -5.6 2.4e-08 -0.55 0.03 0.62 FALSE
7 GTEx Testis PDE4C 0.39 0.44 lasso 2 0.43 5.8e-21 -5.43 -5.4 5.7e-08 -0.39 1.00 0.00 FALSE
8 GTEx Testis AC068499.10 0.38 0.41 lasso 3 0.40 6.8e-19 -5.43 -5.5 3.3e-08 -0.40 1.00 0.00 FALSE
9 GTEx Thyroid KIAA1683 0.11 0.07 enet 14 0.12 2.1e-09 5.16 7.5 5.4e-14 0.62 0.74 0.24 FALSE
10 GTEx Vagina LRRC25 0.63 0.02 enet 2 0.04 5.3e-02 7.68 -7.7 1.5e-14 -0.54 0.04 0.19 TRUE
11 METSIM Adipose CILP2 0.04 0.03 lasso 5 0.07 2.7e-11 -3.17 -5.4 6.9e-08 -0.11 0.14 0.78 TRUE
12 NTR Blood IFI30 0.03 0.02 lasso 6 0.02 8.8e-08 7.54 6.2 4.3e-10 0.82 0.08 0.92 FALSE
13 ROSMAP Brain Pre-frontal Cortex PDE4C 0.18 0.12 enet 17 0.19 3.3e-24 -2.81 -5.9 4.2e-09 -0.75 0.58 0.42 FALSE
14 ROSMAP Brain Pre-frontal Cortex KIAA1683 0.23 0.14 bslmm 409 0.24 1.4e-30 -1.90 5.3 1.0e-07 0.47 0.95 0.05 FALSE
15 ROSMAP Brain Pre-frontal Cortex JUND 0.17 0.17 lasso 5 0.20 2.7e-25 7.68 6.8 7.4e-12 0.55 0.78 0.22 FALSE
16 YFS Blood KIAA1683 0.51 0.40 enet 65 0.46 9.9e-171 7.67 5.7 1.4e-08 0.46 0.80 0.20 FALSE
17 YFS Blood MAST3 0.06 0.04 lasso 5 0.04 4.2e-12 7.77 -7.5 8.9e-14 -0.71 0.46 0.54 FALSE
18 The Cancer Genome Atlas Glioblastoma Multiforme JUND 0.17 0.00 blup 57 0.03 5.4e-02 7.68 7.3 4.0e-13 0.57 0.01 0.59 FALSE
19 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma JUND 0.05 0.04 lasso 1 0.04 4.3e-05 7.68 7.7 1.5e-14 0.54 0.10 0.39 FALSE
20 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MAST3 0.04 0.02 blup 65 0.01 7.3e-02 7.77 -6.1 1.0e-09 -0.60 0.01 0.49 FALSE
21 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma JUND 0.11 0.03 blup 58 0.04 1.4e-03 -2.74 6.5 9.2e-11 0.37 0.04 0.08 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma JUND 0.04 0.03 lasso 2 0.02 7.9e-04 7.68 7.6 3.1e-14 0.54 0.13 0.34 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma MAST3 0.02 0.02 lasso 3 0.01 1.5e-02 7.36 -7.5 8.5e-14 -0.48 0.06 0.57 FALSE
24 The Cancer Genome Atlas Lung Squamous Cell Carcinoma IL12RB1 0.07 0.04 blup 58 0.06 4.9e-07 4.38 -5.8 6.6e-09 -0.45 0.87 0.11 FALSE
25 The Cancer Genome Atlas Lung Squamous Cell Carcinoma KIAA1683 0.09 0.05 lasso 4 0.06 1.3e-07 7.68 5.6 1.7e-08 0.46 0.78 0.15 FALSE
26 The Cancer Genome Atlas Testicular Germ Cell Tumors IL12RB1 0.10 0.01 enet 10 0.06 2.6e-03 1.97 -6.3 2.5e-10 -0.46 0.01 0.68 TRUE
27 The Cancer Genome Atlas Thyroid Carcinoma IL12RB1 0.08 0.04 lasso 3 0.05 8.9e-06 4.03 -5.2 1.8e-07 -0.45 0.30 0.52 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma MAST3 0.04 0.02 lasso 2 0.00 3.4e-01 7.36 -7.4 1.5e-13 -0.48 0.07 0.40 FALSE