[Hub]/) : Traits : Hip circumference : ← →

chr12:109,866,528-113,517,494

Best TWAS P=2.51e-12 · Best GWAS P=7.61e-13 conditioned to 0.0249

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Artery Tibial	HECTD4	0.05	0.02	lasso	3	0.01	3.1e-02	-6.6	-7.0	2.5e-12	0.85	0.02	0.92	TRUE
18	GTEx	Skin Not Sun Exposed Suprapubic	VPS29	0.06	0.01	lasso	3	0.01	6.9e-02	5.5	6.0	2.1e-09	-0.01	0.04	0.67	TRUE
17	GTEx	Nerve Tibial	HECTD4	0.05	0.01	enet	6	0.01	3.6e-02	6.0	-6.6	4.9e-11	0.48	0.21	0.49	FALSE
22	GTEx	Skin Sun Exposed Lower leg	ALDH2	0.10	0.09	enet	13	0.13	6.7e-11	4.1	-6.2	7.0e-10	0.67	0.49	0.51	FALSE
1	GTEx	Adipose Subcutaneous	HECTD4	0.06	0.00	enet	15	0.02	1.0e-02	4.3	-6.1	1.3e-09	0.66	0.06	0.84	FALSE
26	NTR	Blood	GPN3	0.03	0.01	blup	236	0.02	2.7e-06	5.1	-5.9	3.3e-09	0.06	0.06	0.94	FALSE
13	GTEx	Muscle Skeletal	VPS29	0.06	0.06	lasso	3	0.05	4.3e-06	6.1	5.9	4.2e-09	-0.04	0.00	0.99	FALSE
7	GTEx	Cells Transformed fibroblasts	VPS29	0.09	0.13	lasso	3	0.13	9.8e-10	6.1	5.8	5.3e-09	-0.03	0.00	1.00	FALSE
31	The Cancer Genome Atlas	Brain Lower Grade Glioma	VPS29	0.06	0.06	enet	7	0.06	2.1e-07	5.4	5.8	6.8e-09	0.00	0.01	0.99	FALSE
2	GTEx	Adrenal Gland	PPTC7	0.13	-0.01	lasso	6	0.00	3.4e-01	5.5	5.8	6.9e-09	-0.19	0.03	0.17	FALSE
3	GTEx	Artery Tibial	VPS29	0.05	0.03	lasso	3	0.02	5.9e-03	6.1	5.7	9.6e-09	-0.07	0.01	0.96	FALSE
9	GTEx	Esophagus Mucosa	VPS29	0.14	0.13	lasso	6	0.13	3.0e-09	5.1	5.7	1.1e-08	-0.01	0.02	0.98	FALSE
14	GTEx	Muscle Skeletal	IFT81	0.08	0.08	lasso	5	0.07	1.7e-07	5.5	5.7	1.1e-08	0.01	0.07	0.93	FALSE
15	GTEx	Muscle Skeletal	ANAPC7	0.08	0.01	lasso	3	0.00	1.1e-01	5.1	5.7	1.2e-08	-0.01	0.03	0.77	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	VPS29	0.02	0.02	lasso	5	0.03	4.6e-06	5.3	5.7	1.2e-08	-0.01	0.01	0.99	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	RAD9B	0.04	0.02	blup	29	0.03	4.9e-04	5.5	5.7	1.4e-08	0.00	0.01	0.89	FALSE
23	GTEx	Spleen	VPS29	0.24	0.01	enet	14	0.04	2.9e-02	5.2	5.6	2.4e-08	0.04	0.05	0.48	FALSE
11	GTEx	Lung	GPN3	0.08	0.08	enet	8	0.07	1.0e-05	5.2	-5.4	5.2e-08	0.00	0.21	0.78	FALSE
5	GTEx	Breast Mammary Tissue (Female)	VPS29	0.10	-0.01	lasso	2	0.02	1.0e-01	-3.6	5.4	5.4e-08	-0.24	0.02	0.32	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	ARPC3	0.13	0.09	lasso	4	0.04	2.0e-02	5.5	-5.4	5.4e-08	0.00	0.06	0.60	FALSE
27	YFS	Blood	ARPC3	0.06	0.04	lasso	4	0.05	7.9e-16	5.3	-5.4	6.5e-08	-0.04	0.13	0.87	FALSE
20	GTEx	Skin Sun Exposed Lower leg	ARPC3	0.13	0.15	lasso	3	0.15	1.9e-12	5.3	-5.3	9.2e-08	0.00	0.11	0.89	FALSE
12	GTEx	Muscle Skeletal	ARPC3	0.14	0.11	enet	23	0.10	2.2e-10	5.4	-5.3	9.3e-08	-0.04	0.09	0.91	FALSE
35	The Cancer Genome Atlas	Thyroid Carcinoma	RAD9B	0.10	0.06	enet	5	0.06	1.2e-06	5.3	5.3	9.5e-08	0.00	0.05	0.94	FALSE
21	GTEx	Skin Sun Exposed Lower leg	VPS29	0.05	0.04	lasso	6	0.03	1.0e-03	5.1	5.3	9.9e-08	-0.03	0.02	0.94	FALSE
25	GTEx	Testis	ARPC3	0.16	0.16	lasso	3	0.14	7.5e-07	5.3	-5.3	1.0e-07	0.00	0.10	0.90	FALSE
10	GTEx	Esophagus Muscularis	VPS29	0.08	0.04	lasso	4	0.03	9.0e-03	5.1	5.3	1.2e-07	-0.01	0.02	0.92	FALSE
32	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ERP29	0.11	0.03	blup	25	0.05	5.0e-03	4.3	5.3	1.4e-07	-0.59	0.01	0.75	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	MAPKAPK5-AS1	0.04	0.00	enet	30	0.00	7.0e-01	4.3	5.2	1.8e-07	-0.52	0.20	0.18	FALSE
34	The Cancer Genome Atlas	Thyroid Carcinoma	IFT81	0.06	0.09	lasso	1	0.09	3.8e-09	5.2	-5.2	1.8e-07	0.00	0.02	0.98	FALSE
8	GTEx	Colon Transverse	VPS29	0.13	0.01	enet	41	0.10	2.0e-05	5.2	5.2	2.1e-07	-0.05	0.04	0.60	FALSE
29	The Cancer Genome Atlas	Colon Adenocarcinoma	ALDH2	0.07	0.03	lasso	4	0.06	3.9e-04	3.7	-5.2	2.2e-07	0.48	0.05	0.67	FALSE
16	GTEx	Nerve Tibial	VPS29	0.05	0.01	lasso	4	0.00	2.5e-01	5.3	5.2	2.6e-07	0.02	0.02	0.76	FALSE
24	GTEx	Testis	MAPKAPK5	0.23	0.12	lasso	5	0.15	3.1e-07	4.1	-5.1	2.7e-07	0.40	0.66	0.28	FALSE
33	The Cancer Genome Atlas	Thyroid Carcinoma	C12orf24	0.08	0.08	lasso	3	0.10	1.6e-09	5.3	-5.1	2.8e-07	0.02	0.01	0.99	FALSE