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chr17:27,200,734-30,380,381

Best TWAS P=8.51e-13 · Best GWAS P=1.83e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	NF1	0.06	0.01	blup	410	0.04	1.1e-05	6.5	5.5	3.0e-08	0.63	0.22	0.76	TRUE
2	GTEx	Adipose Visceral Omentum	TEFM	0.12	0.02	lasso	14	0.05	1.0e-03	1.5	-6.0	1.7e-09	-0.67	0.06	0.39	TRUE
3	GTEx	Artery Aorta	ABHD15	0.20	0.03	enet	36	0.06	2.9e-04	-2.7	-6.2	7.7e-10	-0.06	0.03	0.37	TRUE
4	GTEx	Artery Tibial	RP11-848P1.7	0.54	0.00	lasso	10	0.02	7.3e-03	-4.3	-6.9	5.5e-12	-0.45	0.02	0.13	FALSE
5	GTEx	Cells EBV-transformed lymphocytes	EVI2A	0.13	0.03	lasso	4	0.01	1.5e-01	6.5	-7.1	1.2e-12	-0.93	0.05	0.71	FALSE
6	GTEx	Cells Transformed fibroblasts	OMG	0.06	0.02	lasso	2	0.01	2.5e-02	6.5	6.7	2.8e-11	0.79	0.06	0.63	FALSE
7	GTEx	Spleen	EVI2A	0.22	0.12	lasso	4	0.07	8.3e-03	7.0	-6.6	3.3e-11	-0.92	0.03	0.72	FALSE
8	GTEx	Spleen	OMG	0.41	0.10	enet	26	0.08	4.5e-03	6.5	5.9	4.4e-09	0.70	0.16	0.75	FALSE
9	GTEx	Whole Blood	EVI2A	0.07	0.04	lasso	4	0.04	2.6e-04	6.9	-7.1	1.4e-12	-0.94	0.06	0.94	FALSE
10	METSIM	Adipose	NF1	0.04	0.00	blup	396	0.01	5.5e-03	7.0	6.6	4.0e-11	0.73	0.14	0.83	TRUE
11	METSIM	Adipose	TEFM	0.08	0.06	blup	246	0.06	8.8e-10	-6.6	-5.7	1.2e-08	-0.08	0.16	0.84	TRUE
12	YFS	Blood	EVI2A	0.03	0.05	lasso	4	0.04	1.0e-13	7.0	-7.1	1.3e-12	-1.00	0.02	0.98	FALSE
13	YFS	Blood	EVI2B	0.01	0.00	blup	339	0.00	6.4e-02	-2.4	5.6	2.2e-08	0.71	0.06	0.22	TRUE
14	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	EVI2A	0.03	0.03	blup	37	0.03	2.3e-03	6.9	-6.8	9.1e-12	-0.95	0.02	0.80	FALSE
15	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	OMG	0.02	0.02	blup	31	0.02	3.2e-03	6.9	-7.1	1.4e-12	-0.92	0.02	0.87	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	EVI2A	0.03	0.03	blup	38	0.03	6.9e-07	6.9	-7.1	1.0e-12	-0.92	0.02	0.98	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	OMG	0.03	0.04	lasso	1	0.04	1.1e-08	6.4	-6.4	1.2e-10	-0.75	0.15	0.85	FALSE
18	The Cancer Genome Atlas	Esophageal Carcinoma	OMG	0.09	0.09	blup	31	0.11	2.0e-04	6.5	-7.0	2.2e-12	-0.89	0.03	0.89	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EVI2A	0.04	0.00	blup	37	0.01	1.1e-02	6.8	-5.6	2.1e-08	-0.88	0.01	0.52	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	OMG	0.02	0.02	blup	31	0.03	6.9e-04	6.5	-7.1	1.6e-12	-0.91	0.02	0.89	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	EVI2A	0.03	0.03	blup	38	0.04	3.0e-05	6.9	-7.1	1.6e-12	-0.92	0.03	0.97	FALSE
22	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	NF1	0.04	0.03	blup	111	0.03	1.3e-02	6.4	6.8	7.8e-12	0.85	0.07	0.52	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	EVI2A	0.04	0.06	blup	38	0.06	3.0e-07	6.8	-7.0	2.3e-12	-0.93	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Lung Adenocarcinoma	OMG	0.05	0.03	lasso	5	0.04	3.6e-05	6.9	-6.7	1.5e-11	-0.88	0.02	0.96	TRUE
25	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EVI2A	0.03	0.03	lasso	1	0.02	2.4e-03	6.9	-6.9	6.2e-12	-0.98	0.02	0.74	FALSE
26	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	OMG	0.05	0.03	blup	32	0.03	5.6e-03	6.5	-6.2	5.7e-10	-0.66	0.04	0.31	TRUE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	EVI2A	0.08	0.12	lasso	3	0.12	1.3e-12	7.0	-7.2	8.5e-13	-0.97	0.02	0.98	TRUE
28	The Cancer Genome Atlas	Thyroid Carcinoma	OMG	0.02	0.01	blup	32	0.02	4.8e-03	6.5	-7.0	2.3e-12	-0.91	0.02	0.85	TRUE