Hub : Genes

MRPL45P2

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0680	0.0290	6.0e-04	0.048	NA	0.084	NA	0.071	7.9e-05	NA	2.1e-07	NA	1.8e-06
2	GTEx	Adipose Visceral Omentum	0.2450	0.0770	9.9e-04	-0.005	NA	0.008	NA	-0.004	7.5e-01	NA	1.2e-01	NA	5.5e-01
3	GTEx	Adrenal Gland	0.1821	0.0640	3.9e-05	0.150	NA	0.092	NA	0.039	5.0e-06	NA	3.4e-04	NA	1.5e-02
4	GTEx	Artery Tibial	0.0480	0.0234	4.2e-03	0.065	NA	0.036	NA	0.055	8.6e-06	NA	7.5e-04	NA	3.8e-05
5	GTEx	Cells EBV-transformed lymphocytes	0.3690	0.0770	1.7e-09	0.406	NA	0.392	NA	0.420	2.0e-14	NA	7.4e-14	NA	5.3e-15
6	GTEx	Cells Transformed fibroblasts	0.1370	0.0410	3.1e-08	0.142	NA	0.125	NA	0.126	8.8e-11	NA	1.3e-09	NA	1.1e-09
7	GTEx	Colon Sigmoid	0.1310	0.0670	9.4e-03	0.054	NA	-0.008	NA	0.008	5.6e-03	NA	9.9e-01	NA	1.6e-01
8	GTEx	Esophagus Mucosa	0.1060	0.0350	1.8e-07	0.128	NA	0.108	NA	0.106	7.4e-09	NA	1.1e-07	NA	1.5e-07
9	GTEx	Esophagus Muscularis	0.0960	0.0400	2.1e-04	0.061	NA	0.034	NA	0.048	1.4e-04	NA	3.8e-03	NA	6.5e-04
10	GTEx	Muscle Skeletal	0.0877	0.0260	2.1e-09	0.103	NA	0.089	NA	0.097	2.7e-10	NA	5.0e-09	NA	9.8e-10
11	GTEx	Nerve Tibial	0.0920	0.0309	2.2e-06	0.141	NA	0.124	NA	0.122	3.3e-10	NA	4.1e-09	NA	5.6e-09
12	GTEx	Pancreas	0.1030	0.0500	8.6e-03	0.021	NA	0.042	NA	0.039	4.4e-02	NA	7.3e-03	NA	9.2e-03
13	GTEx	Skin Sun Exposed Lower leg	0.1680	0.0420	1.9e-12	0.167	NA	0.163	NA	0.172	9.8e-14	NA	2.0e-13	NA	3.8e-14
14	GTEx	Stomach	0.1460	0.0490	3.1e-06	0.138	NA	0.112	NA	0.138	3.8e-07	NA	5.1e-06	NA	3.8e-07
15	GTEx	Thyroid	0.0870	0.0290	1.8e-06	0.128	NA	0.136	NA	0.135	5.1e-10	NA	1.3e-10	NA	1.6e-10

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Bipolar Disorder (2018)	0.9	1.4	2.7	0.7	1.0	1.6	0.8	1.1	0.6	1.2	1.3	1.4	1.6	-1.1	0.1	1.3	1.1	-1.5
Bipolar Disorder or Schizophrenia	0.6	1.3	3.8	0.7	0.7	1.5	0.7	1.0	0.7	1.2	1.0	1.2	1.4	-1.9	0.1	1.1	1.0	-1.8
Depressed Affect (Nagel 2018)	0.5	0.9	1.6	-1.2	-0.9	-1.1	-1.0	-1.1	-1.1	-1.0	-0.8	-0.8	-0.6	1.2	-0.4	-0.8	-1.1	1.0
Depression (Nagel 2018)	4.7	7.1	9.2	-2.9	-0.4	-2.5	-2.8	-2.9	-2.9	-2.8	-3.0	-3.0	-3.0	2.6	-1.2	-2.9	-3.0	2.7
Intelligence (Savage-Jansen 2018)	0.5	1.5	2.7	0.5	-0.5	1.4	1.5	1.5	1.4	-0.2	1.1	1.3	0.9	-1.1	1.6	1.3	1.5	-1.4
Neuroticism (Nagel 2018)	0.5	1.1	2.8	-0.9	-0.5	-1.0	-1.0	-1.3	-1.5	-0.3	-1.1	-0.8	-0.5	1.7	-0.4	-1.1	-1.3	1.4
Schizophrenia (2018)	0.2	0.4	2.6	-0.0	-0.0	0.6	0.3	0.4	0.3	0.5	0.3	0.4	0.5	-1.6	0.0	0.4	0.4	-1.0
Schizophrenia vs Biploar Disorder	0.1	0.2	0.8	-0.1	-0.4	-0.6	-0.2	-0.1	0.2	-0.6	-0.3	-0.4	-0.7	-0.1	0.9	-0.2	-0.3	0.5
Worry (Nagel 2018)	0.7	1.4	3.2	-0.9	-0.0	-0.9	-1.4	-1.5	-1.6	-0.1	-1.3	-1.1	-0.8	1.5	-0.3	-1.3	-1.5	1.8
Alzheimer’s Disease (in mother)	0.7	0.8	2.1	-1.4	-0.8	-0.7	-0.9	-0.9	-1.2	-0.3	-1.1	-1.0	-1.1	0.9	0.6	-1.0	-1.0	0.3
Alzheimer’s Disease (in father)	0.2	0.2	1.3	0.2	-1.0	-0.0	0.1	0.2	0.1	1.1	-0.2	-0.3	-0.5	-0.3	0.6	-0.0	0.0	-0.6
Alzheimer’s Disease (including proxy)	2.7	3.9	5.7	-2.1	-2.1	-2.1	-2.0	-2.0	-2.3	-0.9	-2.3	-2.3	-2.4	1.9	-0.1	-2.2	-2.1	1.4
Crohns Disease (2017)	0.1	0.3	1.5	-0.3	-1.2	-0.1	0.2	0.2	0.3	-0.9	0.1	-0.5	-0.6	0.6	1.0	0.1	-0.1	0.1
Irritable Bowel Disease (IBD)	1.5	3.7	8.7	-1.8	-2.2	-1.9	-1.5	-1.6	-1.4	-3.0	-1.7	-2.1	-2.3	2.0	-0.8	-1.8	-1.9	1.8
Ulcerative Colitis (UC)	2.2	4.1	7.5	-1.6	-1.8	-2.1	-1.9	-1.9	-1.8	-2.7	-2.0	-2.3	-2.4	1.9	-1.6	-2.1	-2.1	2.0
Major Depression (MDD)	1.2	1.5	5.8	-1.4	-2.4	-1.1	-1.0	-0.9	-0.8	-1.9	-1.1	-1.1	-1.1	0.7	0.1	-1.1	-1.1	0.7
Reaction Time	0.5	0.9	3.6	0.5	-0.4	1.1	0.4	0.3	0.5	1.3	0.8	1.1	1.2	-1.3	1.9	0.6	0.4	-0.8
Verbal and Numeric Reasoning (VNR)	1.6	3.8	8.3	1.8	-0.8	1.7	2.1	2.2	2.2	1.1	1.7	1.9	1.5	-2.0	2.9	1.9	2.2	-2.3
Breast Cancer	1.6	3.8	7.1	-1.8	-0.2	-2.7	-2.0	-2.2	-2.1	-1.1	-1.8	-2.2	-2.2	2.1	-1.6	-2.1	-2.1	1.9
Ovarian Cancer	0.3	0.4	5.7	-0.1	-2.4	-0.2	-0.0	-0.0	-0.1	0.3	-0.0	-0.2	-0.3	0.2	0.7	-0.0	-0.2	0.2
Prostate Cancer	0.7	0.9	1.9	-0.9	-0.1	-0.0	-1.1	-1.0	-1.2	-1.0	-1.1	-1.2	-1.0	0.2	-1.4	-1.0	-1.1	0.8
Age at First Birth	0.3	0.4	0.9	-0.0	0.7	0.4	0.5	0.6	0.5	-0.2	0.6	0.8	0.9	-0.8	-0.9	0.7	0.7	-0.3
Bipolar Disorder (2011)	2.1	2.0	4.2	1.2	1.6	2.0	1.1	1.1	0.8	1.9	1.2	1.4	1.6	-1.7	1.0	1.1	1.2	-1.6
Body Mass Index (BMI) (2010)	1.2	1.6	3.1	-1.4	-1.7	-0.8	-1.2	-1.0	-1.2	-1.7	-1.3	-1.6	-1.8	0.6	-0.0	-1.3	-1.4	1.1
Coronary Artery Disease (CAD)	0.1	0.1	0.6	0.2	0.7	0.7	0.3	0.2	0.2	0.1	0.2	0.4	0.5	-0.1	-0.0	0.2	0.2	-0.1
Crohns Disease (2012)	0.1	0.2	1.3	0.0	-0.6	0.4	0.0	0.1	0.1	0.1	0.1	-0.3	-0.4	0.4	1.1	0.0	-0.2	0.3
Mean Putamen Volume	0.2	0.2	0.7	-0.7	0.4	-0.4	-0.4	-0.4	-0.4	-0.7	-0.2	-0.1	-0.2	-0.1	-0.8	-0.4	-0.2	0.0
Fasting Glucose	1.0	1.2	8.8	1.3	0.5	0.7	3.0	0.9	1.1	0.3	0.7	0.6	1.2	-0.2	1.2	0.8	0.7	0.0
HbA1C	1.9	2.1	4.2	1.2	2.0	1.9	1.5	1.4	1.3	0.8	1.4	1.4	1.5	-1.0	1.1	1.6	1.6	-1.1
HDL Cholesterol	2.8	4.7	8.9	1.4	0.1	2.4	2.4	2.5	2.3	1.3	2.6	2.7	3.0	-1.8	-0.4	2.6	2.5	-2.0
LDL Cholesterol	15.2	24.0	38.1	4.3	-0.2	6.2	5.1	5.1	5.1	3.8	5.4	5.3	5.4	-4.8	4.7	5.3	5.2	-4.9
Lupus	1.0	1.6	3.2	0.9	-1.5	1.2	1.4	1.3	1.5	0.4	1.2	1.0	0.8	-1.0	1.8	1.2	1.4	-1.5
Neuroticism (2016)	0.1	0.1	0.6	-0.3	-0.6	0.2	-0.0	-0.0	-0.3	-0.8	-0.0	-0.1	0.1	0.4	0.1	-0.0	-0.0	0.2
Primary Biliary Cirrhosis	0.9	1.2	3.6	-0.3	-1.9	0.6	1.4	1.4	1.3	-0.7	1.0	0.7	0.3	-0.3	1.8	1.0	1.2	-1.1
Rheumatoid Arthritis	0.2	0.3	1.4	-0.5	-0.3	0.0	0.1	0.1	0.1	-0.0	0.1	0.3	0.0	-1.1	1.2	0.1	0.3	-1.0
Schizophrenia (2014)	0.0	0.1	0.3	-0.2	0.5	0.0	-0.1	-0.1	-0.2	0.6	-0.0	0.1	0.2	-0.4	0.0	0.0	-0.2	-0.3
Triglycerides	1.9	3.1	6.2	-1.6	-0.4	-2.0	-1.7	-1.7	-1.6	-2.1	-1.9	-2.2	-2.5	1.6	-0.4	-1.9	-1.9	1.5
Type 2 Diabetes (T2D) (2012)	0.3	0.3	3.1	-0.5	-0.1	-0.3	0.1	-0.0	0.4	-1.8	-0.0	-0.2	-0.4	0.9	0.0	0.1	-0.1	0.5
Ulcerative Colitis	2.8	4.0	7.6	-2.8	-1.9	-1.6	-1.8	-1.8	-2.0	-2.5	-1.9	-2.0	-2.2	2.2	-0.8	-2.0	-1.9	2.1
Blood Eosinophil Count	1.7	12.8	35.5	3.5	6.0	3.8	2.7	2.6	3.1	4.4	3.1	3.6	4.0	-3.2	4.1	3.1	2.8	-2.0
Blood Platelet Count	0.2	2.7	5.2	0.4	-1.3	1.0	1.8	1.8	1.8	-1.7	1.8	1.9	2.3	-1.9	-0.7	2.0	1.8	-1.6
Blood Red Count	0.6	6.2	24.5	-2.5	-4.2	-1.2	-2.0	-2.0	-2.5	-2.3	-1.7	-2.1	-2.0	1.2	-5.0	-1.9	-2.2	1.6
Blood White Count	0.9	7.0	11.3	-3.4	-1.3	-2.2	-2.9	-2.8	-2.8	-2.8	-3.1	-3.2	-3.3	1.5	-1.5	-2.9	-2.9	2.1
Heel T-Score	0.2	1.4	10.8	1.2	3.3	-0.5	-0.8	-0.8	-0.7	1.7	-0.7	-0.5	-0.4	0.8	-0.1	-0.7	-0.9	1.2
BMI	0.7	3.8	32.4	-2.6	-5.7	-1.1	-0.7	-0.7	-1.1	-2.3	-1.0	-1.3	-1.4	0.4	-1.8	-0.8	-1.0	0.6
Height	5.1	98.9	130.0	-9.5	-5.0	-11.4	-10.2	-10.1	-9.9	-10.5	-10.9	-10.9	-11.4	8.4	-9.0	-10.7	-10.2	9.2
Waist Hip Ratio (WHR)	0.8	3.8	6.2	1.5	-0.5	1.3	2.2	2.3	2.4	0.3	2.5	2.3	2.2	-2.1	0.9	2.2	2.3	-2.3
Systolic Blood Pressure	0.7	3.3	9.1	1.9	3.0	0.9	2.1	2.1	2.3	-1.0	1.6	2.1	2.0	-0.4	-1.0	2.0	1.8	-0.7
Smoking Status	3.6	8.5	11.0	-3.1	-1.7	-2.7	-3.2	-3.3	-3.3	-2.6	-3.3	-3.2	-3.1	2.7	-1.5	-3.3	-3.2	2.7
Allergy or Eczema	0.9	2.3	4.8	-0.0	-0.8	-2.2	-1.8	-1.7	-1.5	0.2	-2.0	-1.8	-1.9	0.7	-0.7	-1.9	-1.8	1.5
Cardiovascular Disease	5.1	16.7	25.4	3.3	1.5	4.5	5.0	5.0	4.9	0.5	4.9	4.7	4.7	-3.2	1.2	5.0	4.8	-3.9
Hypothyroidism (self reported)	4.9	11.3	24.7	-3.4	-2.1	-3.4	-2.8	-2.8	-3.3	-3.3	-3.2	-3.9	-4.2	5.0	-1.0	-3.2	-3.3	3.8
Respiratory disease	0.2	0.4	2.7	0.5	-1.4	-0.7	-0.1	0.1	0.6	0.3	0.1	0.2	0.2	-1.6	-0.2	0.1	0.1	-0.5
Type 2 Diabetes (T2D) (2018)	2.2	4.1	6.8	2.0	0.7	1.5	2.6	2.5	2.6	0.7	2.4	2.0	1.9	-0.9	2.5	2.4	2.4	-1.8
Lung FEV1/FVC ratio	0.9	4.8	8.0	2.7	-0.6	2.0	2.8	2.8	2.7	1.4	2.4	2.0	1.6	-1.4	1.8	2.5	2.7	-2.2
Lung FVC	0.7	3.4	5.7	0.6	2.4	-1.3	-1.9	-2.0	-1.7	2.1	-2.0	-1.7	-1.5	1.8	-1.5	-1.9	-2.0	2.4
Neuroticism	0.1	0.4	1.0	-0.3	-0.5	-0.3	-0.8	-0.8	-1.0	0.2	-0.6	-0.5	-0.3	0.7	0.0	-0.6	-0.7	0.7
Chronotype (morning person)	0.4	1.0	3.9	-0.2	-1.8	-1.0	-1.0	-1.0	-1.1	0.2	-0.8	-0.7	-0.7	-0.7	-2.0	-1.0	-0.8	-0.0
Hair Pigment	0.4	12.7	55.4	3.9	3.7	1.0	3.3	3.2	3.5	5.5	3.0	2.5	1.9	0.8	7.4	2.8	3.4	-1.7
Tanning	0.0	0.2	1.3	-0.2	-1.1	0.0	-0.4	-0.4	-0.5	0.0	-0.3	-0.4	-0.2	-0.2	-0.9	-0.3	-0.3	0.3
Hand grip strength (left)	0.2	0.4	2.7	1.0	0.3	-0.5	-0.4	-0.4	-0.5	1.7	-0.2	-0.2	-0.0	-0.4	-1.0	-0.3	-0.3	0.0
Number of treatments/medications taken	1.0	1.8	5.3	0.1	-2.3	0.9	1.5	1.6	1.4	-1.2	1.4	1.1	1.0	-1.5	0.4	1.4	1.4	-1.4
Average weekly spirits intake	0.2	0.2	1.7	0.5	-0.3	0.7	0.1	0.1	-0.1	1.3	-0.1	0.0	-0.1	-0.8	0.1	0.0	0.3	-0.6
Sensitivity / hurt feelings	1.3	2.2	4.8	-0.5	-0.7	-2.2	-1.7	-1.7	-1.6	-0.5	-1.6	-1.7	-1.7	1.7	-0.3	-1.7	-1.7	1.6
Frequency of depressed mood in last 2 weeks	1.1	1.6	4.2	-1.4	0.3	-1.3	-1.3	-1.3	-1.2	-2.0	-1.2	-1.3	-1.2	1.3	-0.8	-1.2	-1.3	1.1
Hearing difficulty/problems: Yes	5.3	8.1	10.6	2.7	-1.4	2.8	3.2	3.2	3.2	1.7	3.0	3.1	2.8	-2.5	2.8	3.0	3.3	-3.1
Relative age of first facial hair	0.6	1.2	2.4	-0.1	-0.1	0.5	1.2	1.3	1.3	0.4	1.6	1.4	1.2	-0.1	1.0	1.3	1.4	-1.4
Other serious medical condition/disability diagnosed by doctor	1.7	2.2	3.6	-1.2	-1.9	-1.4	-1.6	-1.5	-1.6	-0.9	-1.8	-1.8	-1.9	1.1	-0.0	-1.6	-1.6	1.2
Ever used hormone-replacement therapy (HRT)	0.9	1.1	2.2	-0.6	0.8	-1.5	-1.3	-1.3	-1.2	-0.4	-1.2	-1.0	-0.8	0.8	-0.7	-1.2	-1.2	1.3
Ever had hysterectomy (womb removed)	1.1	1.2	3.4	0.9	-0.8	1.2	1.1	1.1	1.2	0.2	1.0	1.2	1.1	-1.8	0.0	1.1	1.1	-1.6
Systolic blood pressure, automated reading	0.5	1.6	5.7	1.8	2.4	0.5	1.2	1.2	1.5	0.4	0.9	1.5	1.5	-0.2	-0.7	1.3	1.1	-0.2
Eye problems/disorders: Diabetes related eye disease	2.2	2.4	4.1	0.7	-0.8	1.4	1.9	2.0	1.6	-0.2	1.7	1.4	1.2	-1.4	1.7	1.8	2.0	-2.0
Angina	7.2	9.4	13.4	2.5	0.3	2.7	3.5	3.5	3.5	1.6	3.5	3.5	3.5	-3.5	1.1	3.5	3.7	-3.4
Medication for hormone replacement therapy	2.6	2.9	4.8	-0.5	1.7	-1.4	-2.2	-2.1	-2.0	0.4	-2.0	-1.9	-1.7	1.4	-0.6	-2.0	-2.0	2.0
Vitamin and mineral supplements	1.5	2.1	4.3	1.4	-0.5	1.9	1.5	1.5	1.4	1.5	1.2	1.2	1.3	-2.1	1.0	1.5	1.4	-1.6
Supplements: Zinc	0.1	0.1	0.2	-0.4	-0.4	-0.4	-0.1	-0.1	-0.2	0.4	0.0	0.1	0.2	0.4	0.4	-0.1	-0.0	0.0
Medication: Co-codamol	1.2	1.4	2.9	1.3	-1.7	0.6	1.2	1.3	1.3	0.9	1.1	1.1	0.9	-1.0	1.5	1.1	1.4	-1.1
Medication: Metformin	4.2	5.9	8.4	2.5	1.1	1.8	2.8	2.8	2.8	2.1	2.9	2.7	2.6	-1.7	2.2	2.7	2.8	-2.2
Diabetes (father)	0.7	0.8	3.9	0.7	-2.0	0.3	0.8	0.7	0.9	-0.9	0.7	0.7	0.5	0.5	1.6	0.7	0.7	-0.2
Diabetes (mother)	0.2	0.3	2.0	-0.9	0.3	-0.4	0.3	0.2	0.2	-1.4	0.0	-0.4	-0.4	0.3	0.1	0.2	-0.0	-0.1
Severe depression (siblings)	0.2	0.2	1.6	-0.3	0.3	-0.3	-0.5	-0.4	-0.3	0.3	-0.0	0.0	0.2	-0.1	-1.3	-0.3	-0.2	0.1
Pack years adult smoking proportion	2.3	3.5	5.3	1.9	-0.5	1.9	2.2	2.2	2.1	1.3	2.3	1.8	1.9	-0.9	2.3	2.3	2.0	-1.4
Impedance of leg (right)	0.6	3.0	4.3	-1.2	1.9	-1.6	-2.1	-2.1	-1.8	-1.3	-2.0	-1.7	-1.3	1.0	-1.8	-1.8	-2.0	1.7
Leg fat-free mass (left)	1.1	5.9	18.9	-2.6	-4.3	-2.9	-1.7	-1.8	-1.9	-3.0	-2.0	-2.4	-2.7	1.7	-2.3	-2.0	-1.9	1.5
Trunk fat percentage	3.1	12.3	21.8	-4.0	-4.7	-4.2	-2.9	-2.9	-3.0	-4.6	-3.2	-3.6	-3.6	1.6	-4.4	-3.0	-3.2	2.3
Hand grip strength (right)	0.2	0.5	2.8	1.7	-0.1	-0.1	0.4	0.4	0.2	1.5	0.4	0.2	0.2	-0.8	-0.2	0.3	0.4	-0.6
Townsend deprivation index at recruitment	0.1	0.1	0.5	-0.2	0.0	0.1	-0.3	-0.4	-0.2	-0.3	0.0	0.2	0.2	0.7	-0.3	-0.3	-0.2	0.4
Current tobacco smoking	0.4	0.6	4.5	-1.6	-2.1	0.1	-0.5	-0.6	-0.7	-0.4	-0.6	-0.4	-0.2	0.2	-0.3	-0.5	-0.6	0.2
Average weekly fortified wine intake	0.3	0.4	2.5	0.2	-1.6	-0.2	-0.1	-0.2	0.1	0.4	-0.4	-0.1	-0.3	0.8	1.2	-0.4	-0.2	0.4
Maternal smoking around birth	0.2	0.3	1.4	-0.5	1.2	0.1	-0.5	-0.5	-0.3	-0.5	-0.2	-0.2	0.2	0.6	-0.0	-0.2	-0.4	0.9
Fed-up feelings	0.1	0.1	0.7	-0.2	0.0	-0.5	0.2	0.3	0.3	-0.5	0.3	0.2	0.4	0.1	0.8	0.4	0.2	-0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	2.9	3.8	5.4	-2.0	-0.2	-1.7	-2.2	-2.2	-2.3	-1.6	-2.2	-2.3	-2.2	2.0	-0.9	-2.1	-2.3	1.9
Relative age voice broke	0.9	1.3	2.3	-0.1	-1.2	0.8	1.1	1.2	1.4	-0.4	1.4	1.3	1.3	-1.3	0.7	1.2	1.2	-1.5
Taking other prescription medications	0.3	0.4	0.9	0.2	-0.2	0.8	0.7	0.8	0.6	0.1	0.7	0.6	0.6	-1.0	0.3	0.7	0.7	-0.8
Age when periods started (menarche)	5.0	12.1	19.4	-3.2	-1.0	-4.4	-3.7	-3.7	-3.5	-3.6	-3.6	-3.8	-3.7	3.5	-2.0	-3.7	-3.7	3.7
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.6	-0.2	0.8	0.1	-0.4	-0.4	-0.3	0.0	-0.4	-0.0	0.1	-0.3	0.1	-0.3	-0.3	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	4.3	-0.4	0.9	-1.6	-1.1	-1.3	-1.3	-0.7	-1.2	-1.2	-1.2	2.1	-1.2	-1.2	-1.3	1.6
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.2	0.2	-0.4	-1.1	-0.8	-0.8	-0.5	-0.4	-0.8	-0.8	-0.7	0.9	-0.4	-0.8	-0.8	0.9
Qualifications: CSEs or equivalent	0.3	0.4	3.3	-0.6	0.6	-0.4	-0.4	-0.3	-0.3	-0.7	-0.3	-0.2	-0.0	-0.3	-1.8	-0.2	-0.3	-0.1
Serious illness, injury or assault to yourself	0.1	0.2	0.5	0.1	-0.7	0.6	0.4	0.3	0.4	-0.6	0.5	0.3	0.4	-0.4	0.1	0.5	0.4	-0.2
High blood pressure	2.3	6.5	9.5	2.6	1.0	2.9	3.1	3.1	3.1	0.2	2.8	2.8	2.6	-2.5	0.6	3.0	3.0	-2.5
Hayfever, allergic rhinitis or eczema	0.9	2.1	3.3	-1.1	-0.8	-1.8	-1.7	-1.7	-1.5	-1.0	-1.8	-1.7	-1.8	0.6	-0.4	-1.7	-1.7	1.2
Multivitamins +/- minerals	2.0	2.5	4.7	-1.1	0.3	-2.2	-1.7	-1.7	-1.6	-1.5	-1.5	-1.4	-1.5	2.2	-1.2	-1.7	-1.6	1.7
Stomach or abdominal pain in last month	0.2	0.2	0.7	0.1	-0.4	0.6	0.4	0.4	0.4	-0.4	0.8	0.5	0.7	-0.0	0.4	0.6	0.5	-0.4
Supplements: Glucosamine	0.4	0.6	2.0	0.6	1.4	-1.1	-0.7	-0.7	-0.8	0.2	-0.6	-0.6	-0.6	0.7	-0.9	-0.7	-0.6	0.4
Diverticular disease/diverticulitis (self-reported)	4.0	4.7	6.8	-1.8	-0.6	-2.5	-2.2	-2.2	-2.2	-2.1	-2.3	-2.2	-2.2	2.0	-2.6	-2.3	-2.4	2.3
Medication: Atenolol	2.3	2.8	3.8	2.0	1.0	1.2	1.9	1.9	1.9	1.8	1.7	1.9	1.8	-1.6	0.2	1.8	1.9	-1.7
Medication: Levothyroxine sodium	5.7	9.6	17.4	-2.7	-1.6	-3.6	-2.7	-2.7	-3.1	-2.8	-3.0	-3.9	-4.1	4.2	-1.2	-3.1	-3.1	3.2
Sitting height	1.8	12.9	16.6	-2.5	-0.4	-3.9	-3.8	-3.8	-3.6	-3.1	-3.9	-4.1	-4.0	3.9	-3.5	-3.9	-3.8	3.8
Chronic bronchitis/emphysema (father)	1.9	2.2	3.5	-1.4	-1.9	-1.7	-1.4	-1.4	-1.3	-1.5	-1.5	-1.8	-1.8	1.3	-0.4	-1.5	-1.5	1.4
High blood pressure (mother)	0.3	0.4	2.0	0.2	-1.3	-0.1	-0.0	-0.1	-0.0	-0.1	-0.4	-0.4	-0.4	1.4	-0.4	-0.1	-0.4	1.2
Body mass index (BMI)	0.3	1.4	16.0	-0.7	-4.0	-0.1	0.6	0.6	0.3	-0.8	0.5	0.0	-0.0	-1.0	-0.8	0.5	0.5	-0.9
Impedance of leg (left)	0.8	3.7	5.2	-1.2	1.7	-2.2	-2.2	-2.3	-1.9	-1.3	-2.2	-2.0	-1.7	1.5	-1.8	-2.0	-2.3	2.1
Leg predicted mass (left)	1.0	5.4	20.1	-2.5	-4.5	-2.7	-1.6	-1.6	-1.8	-2.9	-1.8	-2.3	-2.5	1.6	-2.2	-1.9	-1.7	1.4
Trunk fat mass	3.3	14.0	26.9	-4.2	-5.2	-4.4	-3.1	-3.1	-3.2	-4.7	-3.4	-3.8	-3.9	1.8	-4.6	-3.2	-3.3	2.5
Waist circumference	0.8	3.0	23.3	-2.0	-4.8	-1.6	-0.4	-0.3	-0.6	-2.4	-0.6	-1.0	-1.1	-0.3	-2.2	-0.5	-0.5	-0.1
Number of incorrect matches in round	4.6	7.6	10.9	-2.1	0.6	-3.2	-3.0	-3.0	-2.7	-2.1	-2.9	-3.1	-3.1	2.8	-1.9	-3.1	-3.1	3.3
Past tobacco smoking	3.3	6.0	7.9	2.2	0.8	2.6	2.8	2.8	2.7	2.5	2.7	2.8	2.7	-1.7	2.3	2.8	2.6	-2.0
Alcohol usually taken with meals	2.6	4.2	6.6	-1.8	-0.2	-2.0	-2.3	-2.3	-2.4	-1.3	-2.5	-2.5	-2.6	1.4	-1.5	-2.4	-2.3	1.8
Nervous feelings	0.1	0.3	1.2	-0.0	-1.1	-0.3	-0.5	-0.5	-0.4	-0.0	-0.4	-0.2	-0.2	0.5	-0.7	-0.4	-0.5	0.9
Frequency of tenseness / restlessness in last 2 weeks	2.8	4.4	8.4	-2.2	-2.9	-2.0	-2.0	-2.0	-2.1	-2.0	-2.2	-2.0	-2.2	2.3	-0.4	-2.2	-2.1	2.0
Hearing difficulty/problems with background noise	1.8	2.9	4.2	1.4	-1.6	2.1	1.8	1.8	1.8	0.5	1.8	1.9	1.8	-1.3	1.6	1.8	1.9	-1.7
Hair/balding pattern: Pattern 2	0.6	0.7	1.3	0.4	-0.9	0.6	0.9	0.9	1.0	0.2	1.0	0.8	0.8	-1.1	0.7	0.9	1.0	-1.1
Had menopause	0.2	0.3	1.3	0.6	0.5	-0.2	-0.4	-0.3	-0.1	1.1	-0.4	-0.1	-0.1	-0.3	1.1	-0.3	-0.3	0.3
Had other major operations	0.1	0.1	0.3	0.2	0.0	0.2	0.3	0.2	0.2	-0.2	-0.0	0.3	0.3	-0.5	0.4	0.2	0.1	-0.3
Forced vital capacity (FVC)	2.8	10.9	14.9	-1.8	-0.1	-3.6	-3.6	-3.6	-3.4	-1.8	-3.8	-3.9	-3.8	3.5	-2.9	-3.7	-3.7	3.7
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	3.7	0.2	0.8	-1.2	-1.1	-1.1	-1.0	-0.3	-1.2	-1.3	-1.4	1.9	-0.1	-1.2	-1.3	1.6
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.4	-0.3	-0.2	-0.3	-0.6	-0.7	-0.6	-0.5	-0.5	-0.4	-0.3	1.2	-1.2	-0.6	-0.7	0.8
Qualifications: None of the above	0.2	0.4	1.2	0.4	-0.1	-0.7	-0.5	-0.5	-0.5	0.8	-0.1	-0.2	-0.0	1.1	1.0	-0.3	-0.5	1.1
Financial difficulties in last 2 years	0.7	0.9	2.8	-0.5	0.4	-1.0	-1.0	-1.0	-1.0	-0.1	-0.7	-0.7	-0.4	1.4	-1.7	-0.8	-1.0	1.2
Mouth/teeth dental problems	4.2	6.4	10.3	-1.2	1.9	-2.0	-2.9	-2.9	-2.8	-0.3	-3.0	-3.0	-3.2	2.6	-1.0	-3.1	-2.9	3.1
Heart attack	2.5	3.2	4.4	1.6	0.7	1.7	2.0	2.1	1.9	0.9	1.8	1.9	1.8	-1.7	1.9	1.9	2.1	-2.0
Allergy	0.2	0.5	1.8	0.3	1.3	0.9	0.7	0.7	0.3	0.3	0.8	0.7	0.8	0.4	-0.6	0.7	0.7	-0.1
Pain all over the body in last month	0.8	0.9	2.2	0.8	-0.1	1.5	1.1	1.1	0.9	0.8	0.8	1.0	1.0	-0.7	0.7	1.0	1.0	-1.1
Diabetes (self-reported)	5.6	8.6	13.7	3.6	1.0	2.2	3.4	3.4	3.7	1.9	3.4	3.1	3.1	-2.0	2.7	3.3	3.3	-2.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.8	0.3	-0.3	-0.9	0.1	0.0	0.2	-0.1	-0.0	-0.2	-0.4	0.5	0.2	-0.1	-0.0	0.1
Medication: Ramipril	1.7	2.2	10.1	0.3	-3.2	0.3	1.5	1.6	1.7	-0.6	1.3	1.3	0.9	-2.0	0.7	1.3	1.5	-1.6
Medication: Simvastatin	10.4	15.3	22.6	3.2	0.3	3.4	4.6	4.6	4.8	0.7	4.6	4.4	4.1	-4.1	3.2	4.4	4.5	-4.3
Fluid intelligence score	0.9	1.9	4.1	1.4	-0.8	1.2	1.6	1.5	1.5	0.9	1.3	1.4	1.2	-0.6	2.0	1.4	1.6	-1.5
Illnesses of siblings	0.4	0.5	1.7	-0.8	-0.4	0.0	-0.6	-0.7	-0.6	-0.5	-0.7	-0.5	-0.5	0.9	1.3	-0.7	-0.7	0.8
Neuroticism score	0.1	0.2	1.2	0.7	0.1	-0.0	0.0	0.1	0.0	1.1	0.3	0.3	0.6	-0.0	0.3	0.3	0.1	-0.1
Weight	2.0	9.9	26.3	-3.4	-5.1	-3.7	-2.5	-2.5	-2.8	-3.6	-2.8	-3.2	-3.4	1.8	-3.4	-2.7	-2.7	2.0
Impedance of arm (right)	3.2	14.9	22.6	-3.2	0.7	-4.8	-4.1	-4.1	-3.6	-3.4	-4.3	-4.2	-4.0	3.4	-4.2	-4.1	-4.2	4.0
Arm fat percentage (right)	1.1	4.3	16.5	-2.3	-4.1	-2.4	-1.3	-1.3	-1.4	-2.5	-1.5	-1.9	-1.9	0.7	-3.2	-1.4	-1.5	1.1
Trunk fat-free mass	0.9	5.3	11.9	-2.3	-3.5	-2.7	-2.0	-2.1	-2.2	-2.3	-2.1	-2.4	-2.6	1.8	-2.0	-2.3	-2.0	1.6
Hip circumference	2.6	11.4	29.5	-4.3	-5.4	-3.4	-2.7	-2.6	-3.1	-4.0	-3.1	-3.5	-3.6	1.6	-3.8	-2.9	-2.9	2.0
Time employed in main current job	1.4	1.6	2.5	-1.0	1.1	-0.5	-1.6	-1.6	-1.6	-0.8	-1.4	-1.3	-1.1	1.0	-1.2	-1.4	-1.4	1.2
Alcohol intake versus 10 years previously	0.2	0.3	1.5	-0.0	0.1	-1.2	-0.3	-0.3	-0.2	-0.5	-0.4	-0.5	-0.5	0.4	0.6	-0.4	-0.3	0.4
Father’s age at death	4.9	6.6	8.5	-2.2	-1.4	-2.9	-2.8	-2.8	-2.6	-1.9	-2.9	-2.5	-2.6	2.2	-2.8	-2.9	-2.7	2.6
Worrier / anxious feelings	0.1	0.2	1.5	0.4	1.2	0.3	0.1	0.1	0.0	1.0	0.2	0.3	0.5	0.3	-0.1	0.2	0.1	0.1
Frequency of tiredness / lethargy in last 2 weeks	2.4	4.0	6.0	-2.0	-2.2	-1.8	-1.9	-1.9	-1.9	-2.5	-2.3	-2.4	-2.4	1.6	-0.9	-2.0	-2.2	1.4
Falls in the last year	2.6	3.6	6.0	-1.6	-1.0	-2.1	-2.1	-2.1	-1.8	-1.6	-2.1	-1.6	-1.8	2.5	-0.7	-2.1	-2.1	2.3
Hair/balding pattern: Pattern 3	0.2	0.3	1.9	0.4	0.5	0.2	-0.5	-0.5	-0.4	1.0	-0.5	-0.2	-0.1	-0.3	-1.4	-0.4	-0.4	0.4
Number of live births	0.9	1.3	2.9	-0.1	-0.9	1.4	1.1	1.1	1.0	0.1	1.2	1.2	1.2	-1.7	1.1	1.2	1.1	-1.7
Forced expiratory volume in 1-second (FEV1)	1.0	3.5	5.9	-0.3	-0.1	-2.2	-1.8	-1.9	-1.7	-0.6	-2.1	-2.3	-2.4	2.4	-1.9	-2.1	-2.0	2.2
Pulse rate	0.3	0.5	3.9	-0.3	-2.0	0.1	-0.6	-0.6	-0.8	0.6	-0.6	-0.5	-0.4	0.0	0.2	-0.5	-0.5	0.2
Happiness	1.8	2.2	6.3	1.4	0.9	1.2	1.5	1.4	1.5	0.7	1.5	1.7	1.6	-1.0	2.5	1.5	1.5	-1.6
Noisy workplace	0.6	0.8	2.1	-0.1	-1.0	0.6	0.9	0.9	0.8	0.1	1.0	0.9	1.1	-0.7	1.4	1.0	0.8	-0.7
Qualifications: A levels/AS levels or equivalent	1.2	2.6	4.2	1.0	0.8	1.7	2.0	2.0	2.0	0.8	1.7	1.6	1.5	-1.6	1.2	1.9	2.0	-1.8
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.6	0.2	0.1	0.2	-0.0	0.0	0.2	0.8	0.2	-0.1	-0.1	-0.3	0.5	-0.0	0.2	-0.3
Mouth/teeth dental problems: Dentures	4.3	7.2	12.7	1.1	-3.6	2.2	2.9	2.9	2.6	0.6	2.9	3.2	3.1	-2.7	1.5	3.0	2.9	-3.3
Asthma	0.1	0.2	1.5	-0.1	-0.6	-0.2	0.1	0.1	0.5	-0.1	0.1	0.3	0.4	-1.2	-0.0	0.2	0.1	-0.6
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	2.5	-0.1	-1.6	1.4	1.0	0.9	0.8	0.7	1.3	1.3	1.5	-1.1	0.7	1.2	1.0	-1.3
Medication: Cholesterol lowering	6.9	10.7	16.0	2.9	0.5	3.2	3.8	3.8	3.9	0.9	4.0	3.8	3.8	-3.0	1.7	3.9	3.9	-3.1
Depression (self-reported)	1.8	2.1	4.2	-1.8	-0.5	-1.4	-1.5	-1.6	-1.6	-1.4	-1.7	-1.1	-1.2	2.1	-0.4	-1.5	-1.6	1.6
Medication: Lansoprazole	1.5	1.7	4.2	1.6	0.8	1.1	1.1	1.2	1.2	1.8	1.0	1.1	1.0	-1.1	2.1	1.1	1.2	-1.4
Prospective memory result	2.5	3.1	4.6	-0.5	1.1	-2.0	-2.0	-2.0	-1.9	-0.1	-2.0	-2.0	-2.0	1.3	-2.2	-2.1	-1.9	1.6
Lung cancer (father)	1.2	1.5	5.2	2.3	1.3	1.2	1.0	1.0	1.1	1.5	0.9	0.9	0.8	-0.7	1.6	0.9	1.1	-0.8
Illnesses of mother	0.8	1.0	2.3	0.8	0.4	1.1	0.9	0.9	1.0	-0.1	1.1	1.1	0.9	-1.4	1.1	0.8	1.1	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.5	6.4	-0.6	-0.4	-2.0	-1.9	-1.9	-1.7	-0.9	-2.2	-2.4	-2.5	2.1	-1.9	-2.1	-2.1	2.1
Pulse wave Arterial Stiffness index	6.2	7.3	10.4	-2.5	-1.5	-3.1	-2.8	-2.9	-2.8	-2.7	-3.2	-2.9	-3.2	2.0	-1.5	-3.1	-2.9	2.4
Impedance of arm (left)	2.7	12.5	20.2	-3.2	0.4	-4.5	-3.6	-3.6	-3.2	-3.8	-3.9	-3.8	-3.6	3.0	-3.9	-3.6	-3.8	3.5
Arm fat mass (right)	1.2	5.1	23.7	-2.5	-4.9	-2.5	-1.3	-1.3	-1.5	-2.7	-1.6	-2.1	-2.2	0.6	-3.0	-1.5	-1.5	0.9
Trunk predicted mass	1.0	5.6	11.9	-2.4	-3.5	-2.8	-2.1	-2.2	-2.3	-2.4	-2.2	-2.5	-2.8	1.8	-2.1	-2.4	-2.1	1.7
Standing height	4.2	42.1	61.9	-6.1	-2.9	-7.9	-6.7	-6.7	-6.5	-6.7	-7.0	-7.1	-7.2	5.7	-6.0	-7.0	-6.8	5.9
Length of working week for main job	0.7	0.7	1.3	0.7	-0.2	0.7	0.9	0.9	0.9	0.9	1.1	0.9	0.9	-0.8	0.4	1.0	1.0	-1.0
Exposure to tobacco smoke at home	0.2	0.2	1.2	-0.6	0.9	0.1	-0.4	-0.3	-0.5	0.1	-0.4	-0.4	-0.4	-0.0	-1.1	-0.4	-0.3	0.0
Breastfed as a baby	6.0	7.5	12.2	-2.3	-0.6	-3.5	-3.2	-3.1	-2.9	-2.5	-3.0	-3.0	-2.9	1.4	-2.9	-3.1	-2.9	2.2
Tense / ‘highly strung’	0.9	1.4	2.4	-1.2	-1.1	-1.0	-1.3	-1.3	-1.3	-0.9	-1.2	-1.3	-1.2	1.2	-0.2	-1.2	-1.4	1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.2	0.6	-0.5	0.6	-0.2	-0.5	-0.5	-0.4	-0.3	-0.5	0.0	0.2	0.7	-0.8	-0.4	-0.5	0.4
Hair/balding pattern: Pattern 4	0.2	0.5	1.5	0.1	1.1	-0.5	-0.8	-0.8	-0.6	0.1	-1.0	-0.8	-0.6	0.2	-0.4	-0.7	-0.9	1.2
Birth weight of first child	5.2	9.5	13.4	-3.7	-0.4	-3.4	-3.4	-3.4	-3.4	-2.8	-3.4	-3.5	-3.5	2.2	-2.3	-3.5	-3.3	2.3
Peak expiratory flow (PEF)	0.7	1.5	5.1	-0.7	-0.4	-1.6	-1.0	-1.1	-0.8	-1.1	-1.1	-1.3	-1.5	2.3	-0.4	-1.2	-1.1	1.7
Pulse wave reflection index	2.8	3.5	5.4	-2.0	-1.1	-2.1	-1.8	-1.8	-1.9	-2.3	-2.0	-1.9	-2.1	1.6	-1.6	-2.0	-1.9	1.4
Ever highly irritable/argumentative for 2 days	0.6	0.7	3.2	1.0	-0.7	0.7	0.8	0.8	0.7	0.5	0.7	0.7	0.6	1.0	1.8	0.7	0.7	0.0
Loud music exposure frequency	0.5	0.6	2.6	-0.4	1.6	-0.1	-0.7	-0.7	-0.8	0.0	-0.5	-0.9	-0.6	0.7	0.6	-0.6	-0.8	0.9
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	4.6	0.6	2.2	1.9	0.9	1.0	0.7	1.1	0.7	0.8	0.7	-2.0	0.1	0.9	1.0	-1.7
Mouth/teeth dental problems: Bleeding gums	1.0	1.4	2.1	0.8	0.9	1.3	1.5	1.4	1.3	0.6	1.3	1.1	1.1	-0.4	1.1	1.4	1.3	-1.3
Blood clot in the leg (DVT)	0.3	0.3	0.7	0.7	-0.6	0.5	0.7	0.6	0.8	0.2	0.7	0.6	0.7	0.4	0.3	0.7	0.6	-0.1
Medication: Paracetamol	3.5	5.8	9.5	0.9	-1.6	2.8	2.7	2.8	2.7	0.2	3.1	2.7	2.8	-1.8	2.3	2.9	2.7	-2.2
Headache pain in last month	0.8	1.4	5.7	0.6	-2.4	1.1	1.0	1.0	0.9	1.0	1.2	1.2	1.2	-0.9	1.2	1.1	1.1	-1.3
Medication for cholesterol, blood pressure or diabetes	5.1	8.5	12.8	-3.0	-0.1	-3.0	-3.5	-3.5	-3.6	-1.2	-3.5	-3.4	-3.4	2.3	-0.8	-3.5	-3.5	2.5
Glaucoma (self-reported)	5.1	6.0	10.7	2.2	1.7	2.0	2.6	2.7	2.7	1.4	2.6	2.6	2.6	-3.3	1.3	2.7	2.7	-2.9
Gout (self-reported)	1.7	2.4	4.5	1.7	1.4	2.1	1.5	1.6	1.4	1.7	1.5	1.4	1.6	-1.6	0.8	1.7	1.5	-1.4
Hypothyroidism/myxoedema (self-reported)	4.8	9.4	21.2	-2.8	-1.3	-3.2	-2.7	-2.7	-3.2	-2.6	-3.0	-3.6	-3.7	4.6	-1.2	-3.0	-3.2	3.6
Medication: Amlodipine	0.9	1.3	3.3	0.5	-1.6	0.8	1.2	1.3	1.2	-0.8	0.9	1.1	0.9	-1.8	-0.7	1.1	1.2	-1.2
Medication: Ventolin 100micrograms inhaler	0.4	0.5	1.6	-0.1	-1.0	-1.3	-0.6	-0.6	-0.3	-0.1	-0.5	-0.8	-0.7	-0.6	-1.1	-0.5	-0.7	0.1
Birth weight	5.1	11.1	14.6	-3.7	-3.2	-3.8	-3.4	-3.4	-3.5	-3.3	-3.5	-3.6	-3.8	2.0	-3.1	-3.6	-3.3	2.4
Chronic bronchitis/emphysema (mother)	0.2	0.3	2.2	-1.5	-1.0	0.3	-0.2	-0.2	-0.2	-0.8	-0.1	-0.1	-0.0	-0.3	0.4	-0.1	-0.1	-0.2
High blood pressure (siblings)	0.7	1.1	1.7	1.2	-0.3	0.5	1.3	1.3	1.2	0.9	1.1	0.8	0.8	-1.1	-0.8	1.3	1.2	-1.2
Forced vital capacity (FVC), Best measure	3.0	10.8	15.2	-1.9	-0.0	-3.5	-3.5	-3.5	-3.4	-2.1	-3.8	-3.9	-3.9	3.3	-3.3	-3.7	-3.7	3.5
Body fat percentage	1.7	6.9	18.2	-2.9	-4.3	-3.1	-1.9	-1.9	-2.1	-3.4	-2.2	-2.6	-2.5	1.0	-3.7	-2.0	-2.2	1.6
Leg fat percentage (right)	0.5	1.9	8.9	-1.5	-3.0	-1.1	-0.9	-0.9	-1.2	-1.6	-0.9	-1.2	-1.0	-0.1	-2.4	-0.8	-1.0	0.6
Arm fat-free mass (right)	0.6	2.9	12.6	-1.6	-3.5	-1.9	-1.3	-1.3	-1.4	-1.9	-1.4	-1.8	-2.0	0.8	-1.1	-1.5	-1.3	0.9
Exposure to tobacco smoke outside home	1.1	1.4	2.4	1.5	-1.2	1.0	1.1	1.1	1.2	1.0	1.4	1.3	1.5	-1.0	0.4	1.3	1.1	-1.2
Comparative body size at age 10	0.3	0.7	6.3	-1.2	-1.0	-0.1	-0.5	-0.4	-0.7	-0.3	-0.5	-0.5	-0.5	0.0	-2.5	-0.5	-0.4	0.2
Number of full brothers	1.5	1.8	3.7	0.7	0.4	1.4	1.1	1.1	1.0	1.0	1.5	1.8	1.9	-1.7	1.6	1.4	1.4	-1.6
Worry too long after embarrassment	2.7	4.6	8.6	2.9	-0.7	2.0	2.2	2.2	2.2	2.3	2.4	2.5	2.6	-1.1	1.0	2.3	2.3	-2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.6	2.3	-0.7	-0.6	-0.7	-0.6	-0.6	-0.3	-1.5	-0.5	-0.3	-0.3	1.1	-0.3	-0.6	-0.7	1.1
Wheeze or whistling in the chest in last year	0.1	0.2	0.9	-0.2	-0.9	0.1	-0.0	-0.1	0.3	-0.4	0.2	0.5	0.7	-0.7	0.3	0.2	0.0	-0.3
Number of children fathered	0.5	0.5	5.0	-0.7	-2.2	0.0	0.4	0.4	0.3	-0.6	0.5	0.1	0.1	-0.5	0.2	0.4	0.5	-0.7
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	2.1	-1.4	-0.4	-0.1	-0.2	-0.3	-0.4	-0.5	0.0	0.0	0.1	-0.2	-0.6	-0.2	-0.1	0.1
Age at first live birth	0.5	0.8	3.5	-1.0	-0.8	-1.2	-0.6	-0.6	-0.3	-1.9	-0.7	-0.8	-0.8	1.1	-0.3	-0.7	-0.7	1.1
Pulse wave peak to peak time	4.6	5.4	8.2	2.1	1.5	2.6	2.5	2.5	2.5	2.3	2.8	2.6	2.9	-1.5	1.1	2.7	2.5	-2.0
Health satisfaction	3.4	4.4	8.7	0.2	-2.2	2.2	2.3	2.4	2.1	-0.5	2.0	1.9	1.8	-2.8	1.7	2.2	2.2	-2.9
Shortness of breath walking on level ground	0.4	0.5	3.7	-0.8	-1.9	-0.1	-0.5	-0.4	-0.5	-0.8	-0.5	-0.5	-0.4	0.1	-0.4	-0.4	-0.4	0.3
Qualifications: College or University degree	0.3	0.9	2.1	-1.2	0.2	-1.4	-0.8	-0.8	-0.9	-1.2	-1.1	-0.9	-1.1	1.2	-0.2	-1.0	-0.7	0.6
Eye problems/disorders: None of the above	6.8	7.9	10.9	-3.3	-1.5	-2.9	-2.9	-3.0	-2.9	-2.9	-3.0	-2.7	-2.7	2.7	-2.6	-2.9	-2.9	2.9
Mouth/teeth dental problems: Loose teeth	1.1	1.3	2.5	0.6	-1.2	1.1	1.1	1.1	1.0	1.6	0.9	1.0	1.1	-1.6	0.8	1.1	1.0	-1.5
Emphysema/chronic bronchitis	0.1	0.2	0.8	-0.5	-0.7	-0.1	-0.3	-0.2	-0.3	-0.3	-0.1	0.1	0.3	-0.9	-0.5	-0.1	-0.2	-0.4
Medication for pain relief, constipation, heartburn	5.5	9.5	13.7	-1.3	2.8	-3.2	-3.5	-3.5	-3.5	-0.3	-3.7	-3.2	-3.4	3.0	-2.0	-3.7	-3.5	3.4
Neck or shoulder pain in last month	1.1	1.6	4.8	1.0	0.4	1.6	1.3	1.3	1.4	0.3	1.3	1.4	1.4	-0.4	2.2	1.3	1.2	-0.5
Medication: Blood pressure	1.8	3.1	4.5	1.8	-1.1	1.7	2.0	2.1	2.1	0.8	1.8	2.0	1.8	-1.8	-0.1	2.0	2.1	-1.8
Angina (self-reported)	6.6	8.7	13.0	2.2	0.4	2.5	3.3	3.4	3.4	1.4	3.4	3.4	3.3	-3.6	1.0	3.4	3.5	-3.4
Migraine (self-reported)	0.0	0.1	0.3	-0.1	-0.1	0.5	-0.1	-0.1	-0.2	0.1	0.0	-0.0	-0.0	0.5	0.4	-0.1	-0.1	0.1
Medication: Ibuprofen	1.7	2.0	3.5	0.5	-1.1	1.8	1.5	1.4	1.4	0.9	1.9	1.6	1.8	-1.2	0.7	1.7	1.5	-1.5
Medication: Allopurinol	0.4	0.5	3.5	0.7	1.9	1.0	0.3	0.3	0.2	1.0	0.4	0.6	0.8	-0.4	0.1	0.5	0.4	-0.3
Medication: Omeprazole	0.2	0.3	2.5	-0.8	-0.6	-0.2	-0.1	-0.2	-0.1	-1.6	-0.4	-0.4	-0.4	-0.1	0.3	-0.2	-0.3	-0.2
Medication: Seretide 50 evohaler	1.9	2.1	6.1	0.0	-0.8	1.4	1.6	1.6	1.4	0.2	1.4	1.3	1.2	-2.4	0.7	1.6	1.5	-2.5
Mean time to correctly identify matches	0.2	0.4	1.5	0.8	-0.3	0.6	0.0	0.0	0.2	1.2	0.3	0.5	0.7	-1.2	1.2	0.2	0.1	-0.3
Heart disease (mother)	0.3	0.4	1.7	0.2	-1.3	0.7	0.5	0.5	0.5	0.2	0.5	0.7	0.8	-0.4	0.1	0.6	0.5	-0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.9	1.1	2.8	0.4	0.1	1.6	0.8	0.8	0.7	1.4	1.1	1.2	1.3	0.2	1.7	1.0	0.9	-0.5
Whole body fat mass	2.0	8.5	26.1	-3.2	-5.1	-3.4	-2.2	-2.1	-2.3	-3.6	-2.4	-2.9	-2.9	1.4	-3.7	-2.3	-2.4	1.8
Leg fat mass (right)	0.9	3.5	16.5	-1.9	-4.1	-2.0	-1.2	-1.2	-1.5	-2.2	-1.3	-1.8	-1.7	0.5	-2.6	-1.2	-1.3	0.9
Arm predicted mass (right)	0.6	2.9	13.1	-1.8	-3.6	-1.8	-1.2	-1.2	-1.4	-2.0	-1.3	-1.7	-1.9	0.6	-1.4	-1.4	-1.2	0.7
Pulse rate, automated reading	1.0	3.4	7.6	2.2	-2.2	1.5	1.8	1.8	1.6	2.8	1.7	1.7	1.8	-1.5	0.6	1.9	1.8	-1.8
Alcohol intake frequency.	1.9	4.5	6.5	-1.9	-1.3	-2.3	-2.0	-2.0	-2.1	-1.9	-2.4	-2.4	-2.5	2.4	-0.9	-2.2	-2.3	2.4
Comparative height size at age 10	0.4	2.1	3.8	-1.4	-1.9	-1.5	-1.4	-1.4	-1.6	-1.4	-1.6	-1.4	-1.6	0.4	-1.9	-1.6	-1.3	0.6
Number of full sisters	0.1	0.2	0.8	-0.1	0.1	-0.0	0.3	0.3	0.3	-0.9	0.1	-0.0	0.0	-0.7	-0.8	0.2	0.1	-0.4
Suffer from ‘nerves’	0.3	0.4	1.3	-0.3	0.2	-0.3	-0.8	-0.7	-0.7	0.1	-0.7	-0.6	-0.5	0.7	0.2	-0.7	-0.8	1.1
Overall health rating	2.3	4.8	7.3	1.7	-0.6	2.4	2.6	2.7	2.5	1.1	2.5	2.4	2.5	-1.8	1.6	2.7	2.5	-2.3
Chest pain or discomfort	11.3	16.3	22.4	3.7	-1.2	3.8	4.5	4.6	4.7	2.2	4.6	4.5	4.6	-4.2	2.1	4.7	4.6	-4.4
Had major operations	0.2	0.3	1.1	0.7	-0.9	-0.4	-0.1	-0.0	-0.0	1.0	-0.1	-0.2	-0.2	0.5	1.0	-0.1	-0.0	0.1
Age at last live birth	0.2	0.4	0.9	-0.7	-0.4	-0.8	-0.5	-0.5	-0.4	-1.0	-0.4	-0.7	-0.7	0.7	-0.4	-0.5	-0.5	0.6
Family relationship satisfaction	0.1	0.1	0.7	0.8	0.4	-0.1	0.0	-0.0	0.2	0.2	0.0	0.0	0.0	0.2	0.7	-0.0	-0.1	0.1
Leg pain on walking	0.6	0.7	1.3	0.8	-0.7	0.3	0.9	0.9	0.9	0.2	0.9	0.8	0.9	-0.9	1.1	0.9	0.9	-1.1
Qualifications: NVQ or HND or HNC or equivalent	5.0	6.1	8.1	2.8	0.9	2.4	2.7	2.7	2.6	2.3	2.8	2.6	2.7	-2.4	1.5	2.8	2.7	-2.3
Commuting to job workplace: Car/motor vehicle	0.2	0.3	2.0	-0.5	-0.9	0.2	0.2	0.2	0.1	-1.4	0.4	0.2	0.3	-0.3	-0.5	0.2	0.2	-0.4
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	1.4	0.3	0.5	1.2	0.8	0.9	0.7	0.8	0.5	0.8	0.7	-0.7	1.0	0.7	0.9	-0.7
Medication: Aspirin	2.2	3.0	4.5	1.5	-0.5	1.5	2.1	2.1	2.1	0.6	1.9	1.7	1.6	-1.9	0.6	2.0	2.1	-2.1
Supplements: Vitamin C	0.3	0.3	0.9	-0.9	0.7	-0.2	-0.7	-0.7	-0.7	-0.7	-0.5	-0.4	-0.5	0.3	0.3	-0.7	-0.6	0.5
Knee pain experienced in last month	0.2	0.3	2.4	0.3	-1.6	-0.2	0.2	0.2	0.4	0.2	0.1	0.3	0.2	0.0	1.0	0.1	0.1	0.0
Hypertension (Self-reported)	2.3	6.3	8.9	2.5	0.9	2.9	3.0	3.0	3.0	0.4	2.7	2.8	2.6	-2.6	0.4	2.9	3.0	-2.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.7	-0.3	-0.1	0.2	0.4	0.4	0.6	-0.9	0.4	0.7	0.6	-0.8	0.3	0.4	0.4	-0.6
Illnesses of father: Heart disease	4.5	6.2	9.7	2.3	0.8	2.2	3.0	3.0	3.1	1.1	3.1	2.6	2.6	-1.9	1.8	3.0	2.9	-2.3
Illnesses of siblings: Diabetes	0.4	0.5	1.5	0.1	-0.1	0.5	0.8	0.8	0.8	0.1	0.6	1.0	0.7	-1.0	0.0	0.7	0.8	-1.2
Smoking status: Previous	2.6	3.9	5.6	-1.0	0.1	-2.4	-2.3	-2.3	-2.3	-1.4	-2.2	-2.3	-2.3	1.5	-1.7	-2.4	-2.1	1.7
Forced expiratory volume in 1-second (FEV1), predicted	1.2	2.4	4.0	-1.3	-0.5	-1.8	-1.6	-1.7	-1.7	-1.1	-1.6	-2.0	-1.9	1.6	-1.4	-1.7	-1.6	1.4
Whole body fat-free mass	1.0	5.5	16.6	-2.4	-4.1	-2.8	-1.9	-1.9	-2.0	-2.6	-2.0	-2.4	-2.7	1.8	-2.0	-2.2	-1.9	1.5
Leg fat-free mass (right)	1.1	5.6	20.2	-2.5	-4.5	-2.9	-1.6	-1.6	-1.8	-3.0	-1.9	-2.3	-2.6	1.9	-2.1	-1.9	-1.8	1.5
Arm fat percentage (left)	1.0	4.0	18.5	-2.3	-4.3	-2.2	-1.0	-1.0	-1.2	-2.8	-1.3	-1.7	-1.7	0.4	-3.0	-1.1	-1.3	0.8
Average weekly red wine intake	0.5	0.8	1.9	-1.1	-1.3	-1.4	-0.7	-0.7	-0.7	-1.0	-0.8	-1.1	-1.2	0.3	-0.2	-0.9	-0.8	0.5
Handedness (chirality/laterality): Left-handed	1.1	1.4	11.4	1.3	3.4	1.2	0.4	0.3	0.2	1.9	0.5	0.6	0.7	-0.1	-0.5	0.5	0.4	-0.1
Mood swings	0.2	0.4	1.7	-1.0	-1.3	-1.1	-0.3	-0.3	-0.3	-0.8	-0.1	-0.1	0.1	0.7	-0.4	-0.1	-0.3	0.5
Loneliness, isolation	0.8	1.1	4.1	2.0	1.4	0.7	1.0	1.1	1.1	1.0	0.9	0.8	0.7	-0.4	1.3	1.0	1.0	-0.7
Long-standing illness, disability or infirmity	0.5	0.8	1.3	0.9	-0.7	0.4	1.1	1.1	1.1	-0.6	1.1	0.7	0.8	-1.1	0.6	1.1	0.9	-1.0
Ever had bowel cancer screening	2.4	2.8	5.5	-1.5	-0.5	-1.9	-1.6	-1.7	-1.4	-2.4	-1.7	-1.6	-1.5	1.4	-2.0	-1.6	-1.6	2.0
Diabetes diagnosed by doctor	4.5	7.3	12.0	3.5	1.2	2.0	3.2	3.1	3.3	1.9	3.2	2.8	2.7	-1.6	2.5	3.1	3.1	-2.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.4	-0.8	-0.4	-0.7	-1.0	-1.1	-1.2	0.3	-1.0	-0.9	-0.9	0.9	0.4	-1.0	-0.9	0.5
Friendships satisfaction	2.1	2.6	4.5	2.1	1.9	1.6	1.6	1.6	1.6	1.4	1.5	1.6	1.4	-0.9	2.1	1.5	1.6	-1.3
Qualifications: nursing, teaching	0.3	0.4	1.4	-0.6	-0.1	-0.6	-0.4	-0.4	-0.5	-0.7	-0.5	-0.6	-0.7	1.2	-0.9	-0.5	-0.4	0.6
Commuting to job workplace: Walk	0.5	0.6	3.8	1.5	0.7	0.2	0.1	0.2	0.2	1.9	0.1	0.2	0.2	-1.0	-0.7	0.2	0.3	-0.3
Eye problems/disorders: Cataract	1.1	1.3	2.5	1.3	0.5	1.4	1.0	1.1	0.9	1.5	1.2	0.9	1.0	-0.8	1.6	1.1	1.1	-1.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	1.1	-0.2	0.3	-1.0	-0.2	-0.2	0.1	-1.1	-0.0	0.2	0.5	0.2	-0.9	0.0	-0.2	0.1
Medication for cholesterol	0.4	0.7	4.1	-1.4	-2.0	-0.5	-0.7	-0.7	-0.8	-0.4	-0.5	-0.5	-0.3	0.7	-0.1	-0.5	-0.6	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.5	-0.4	-0.7	0.4	-0.1	-0.1	-0.2	-0.2	-0.4	-0.1	-0.3	0.4	0.7	-0.2	-0.2	0.2
Back pain experienced in last month	0.9	1.3	3.0	-0.3	-0.5	-1.4	-1.0	-1.1	-0.9	-1.2	-1.3	-1.3	-1.4	1.7	0.2	-1.2	-1.1	1.2
Mineral and other dietary supplements	0.4	0.5	1.6	0.7	-0.5	1.3	0.8	0.8	0.8	0.8	0.7	0.3	0.2	-0.5	0.7	0.8	0.6	-0.2
Breast cancer (self-reported)	0.6	0.8	1.9	0.9	-0.2	0.3	0.9	0.9	1.0	0.1	1.1	0.9	1.1	-1.4	-0.3	1.0	0.9	-1.0
Asthma (self-reported)	0.1	0.1	1.1	-0.2	-0.5	-0.4	-0.2	-0.2	0.2	-0.2	-0.2	0.0	0.1	-1.0	-0.1	-0.1	-0.2	-0.3
Osteoporosis (self-reported)	0.2	0.3	1.5	-1.2	-0.7	0.7	-0.3	-0.2	-0.6	-0.2	-0.4	-0.0	0.1	-0.9	0.2	-0.2	-0.2	-0.4
Osteoarthritis (self-reported)	2.4	3.1	6.3	2.2	1.0	1.5	1.9	1.9	2.0	1.4	2.0	1.6	1.4	-1.4	2.5	1.7	1.9	-1.5
Medication: Aspirin	1.7	2.2	3.5	1.4	-1.0	1.1	1.8	1.9	1.8	0.6	1.7	1.6	1.5	-1.3	0.4	1.7	1.9	-1.6
Medication: Gliclazide	2.4	2.7	4.2	1.2	-0.2	1.6	2.0	2.0	1.8	0.2	2.0	1.6	1.6	-1.5	1.5	2.0	1.9	-1.7
Illnesses of father: None of the above (group 1)	0.4	0.5	1.6	0.1	1.3	-0.9	-0.8	-0.8	-0.6	0.2	-0.6	-0.5	-0.5	0.7	-0.5	-0.8	-0.6	0.6
Smoking status: Current	0.6	1.0	5.2	-1.8	-2.3	-0.3	-0.9	-0.9	-1.0	-0.5	-0.9	-0.7	-0.6	0.3	-0.6	-0.8	-0.9	0.4
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.5	1.5	-0.5	-0.5	-0.6	-0.6	-0.6	-0.6	-0.2	-1.0	-1.0	-1.2	0.2	-0.8	-0.8	-0.7	0.3
Whole body water mass	1.0	5.5	16.6	-2.4	-4.1	-2.8	-1.9	-1.9	-2.1	-2.5	-2.1	-2.4	-2.7	1.8	-2.0	-2.2	-2.0	1.6
Leg predicted mass (right)	1.0	5.5	20.1	-2.5	-4.5	-2.9	-1.5	-1.6	-1.7	-2.9	-1.8	-2.3	-2.6	1.8	-2.1	-1.9	-1.7	1.4
Arm fat mass (left)	1.2	5.1	24.5	-2.5	-4.9	-2.5	-1.3	-1.3	-1.5	-2.9	-1.5	-2.0	-2.2	0.7	-3.0	-1.4	-1.5	1.0
Number of self-reported non-cancer illnesses	1.7	2.9	5.0	1.3	-0.1	1.7	2.2	2.2	2.2	-0.5	2.0	1.8	1.8	-1.0	0.7	2.1	2.0	-1.6
Average weekly champagne plus white wine intake	0.1	0.2	2.1	-0.5	1.5	-0.0	-0.0	-0.0	-0.2	0.1	0.1	0.3	0.4	0.3	-0.2	0.1	0.2	-0.1
Miserableness	0.5	0.9	1.8	0.7	-0.3	0.7	1.1	1.0	1.1	0.7	1.2	1.2	1.3	-0.4	0.6	1.2	1.1	-1.0
Guilty feelings	0.8	1.2	2.2	1.5	0.0	0.7	1.2	1.2	1.2	0.8	1.2	1.3	1.4	-0.8	0.8	1.2	1.2	-1.1
Wears glasses or contact lenses	0.5	0.6	1.9	0.6	-0.2	0.2	0.8	0.8	0.7	1.1	0.5	0.6	0.3	-1.4	0.6	0.6	0.8	-1.2
Ever taken oral contraceptive pill	1.4	1.6	2.8	-0.8	-0.7	-1.1	-1.5	-1.6	-1.5	-0.7	-1.3	-1.3	-1.2	1.7	-0.6	-1.5	-1.3	1.5
Hearing aid user	0.5	0.6	2.6	0.8	-1.6	-0.1	0.9	0.9	0.7	0.1	0.6	0.4	0.4	-0.8	-0.5	0.8	0.7	-1.0
Mother’s age at death	2.4	3.0	6.3	-0.7	0.5	-2.5	-1.9	-1.9	-1.8	-0.9	-1.9	-1.8	-1.9	2.0	-1.1	-2.0	-1.8	2.0
Financial situation satisfaction	0.3	0.3	2.2	-0.6	0.8	-0.6	-0.4	-0.5	-0.1	-1.5	-0.3	-0.2	-0.1	0.5	-0.5	-0.3	-0.5	0.5
Tinnitus: Yes, now most or all of the time	0.5	0.5	4.1	1.3	-2.0	0.3	0.4	0.4	0.4	0.4	0.3	0.3	0.3	0.3	0.9	0.4	0.3	-0.0
Commuting to job workplace: Public transport	0.3	0.4	1.3	-0.2	0.1	0.2	0.6	0.6	0.5	0.7	0.5	0.6	0.5	-1.1	0.1	0.6	0.7	-0.9
Eye problems/disorders: Glaucoma	4.8	5.7	9.5	2.2	1.5	2.0	2.4	2.4	2.5	1.6	2.6	2.6	2.6	-3.1	1.5	2.5	2.5	-2.8
Medication: Blood pressure	1.1	2.1	3.4	1.9	1.6	0.9	1.7	1.7	1.9	-0.2	1.5	1.5	1.3	-1.8	0.1	1.5	1.6	-1.4
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.8	-0.2	-0.6	0.4	0.5	0.6	0.7	-0.4	0.4	0.9	0.9	-0.9	-0.1	0.6	0.6	-0.8
Supplements: Fish oil (including cod liver oil)	0.2	0.2	0.7	-0.0	-0.1	-0.3	0.3	0.4	0.3	-0.0	0.4	0.8	0.8	-0.6	0.3	0.4	0.6	-0.7
High cholesterol (Self-reported)	13.2	23.4	34.8	4.1	1.6	4.8	5.7	5.6	5.5	2.2	5.9	5.7	5.7	-3.8	2.7	5.7	5.7	-4.6
Medication: Bendroflumethiazide	0.2	0.3	2.5	-0.2	0.9	0.0	0.5	0.4	0.5	-1.6	0.3	0.1	0.0	0.4	0.1	0.4	0.4	0.2
Medication: Paracetamol	2.5	3.9	6.2	0.9	-1.6	2.3	2.2	2.2	2.2	0.3	2.5	2.3	2.4	-1.4	1.7	2.3	2.2	-1.7
Medication: Lisinopril	1.9	2.4	8.9	2.9	3.0	1.3	1.4	1.3	1.5	1.6	1.4	1.1	1.1	-0.4	-0.6	1.4	1.3	-0.4
Medication: Atorvastatin	7.4	9.1	14.2	2.5	0.5	3.4	3.6	3.6	3.3	1.7	3.8	3.4	3.6	-2.2	1.5	3.7	3.5	-2.8
Illnesses of father: High blood pressure	0.3	0.4	2.2	-0.2	-1.5	0.4	0.6	0.6	0.5	-0.0	0.5	0.2	0.3	-1.0	0.2	0.6	0.5	-0.8
Alcohol drinker status: Never	2.6	3.1	4.4	-1.9	-2.1	-1.4	-1.8	-1.8	-1.9	-1.4	-1.9	-1.7	-1.7	1.2	-2.0	-1.8	-1.9	1.5
Ever smoked	4.3	7.6	9.7	-2.7	-0.9	-2.7	-3.1	-3.1	-3.0	-2.9	-3.0	-3.1	-3.1	2.4	-1.9	-3.1	-2.9	2.6
Basal metabolic rate	1.2	6.7	19.8	-2.7	-4.5	-3.1	-2.0	-2.1	-2.2	-2.9	-2.2	-2.6	-2.9	1.8	-2.5	-2.3	-2.1	1.7
Leg fat percentage (left)	0.5	1.9	9.0	-1.3	-3.0	-1.3	-0.8	-0.9	-1.1	-1.4	-1.0	-1.3	-1.1	0.1	-2.3	-0.8	-1.0	0.6
Arm fat-free mass (left)	0.9	4.7	12.7	-2.0	-3.6	-2.4	-1.9	-1.9	-2.1	-2.0	-2.0	-2.3	-2.5	1.4	-1.7	-2.1	-2.0	1.6
Number of operations (self-reported)	0.4	0.7	1.3	-0.4	-1.0	-1.2	-0.9	-1.0	-0.8	-0.4	-1.0	-0.7	-0.7	0.7	-0.1	-0.9	-0.9	0.9
Average weekly beer plus cider intake	0.7	0.9	2.6	-1.3	-0.4	-0.5	-1.1	-1.2	-1.1	-1.6	-0.9	-0.8	-0.5	0.9	-0.7	-0.9	-1.0	1.0
Irritability	3.9	6.6	9.8	2.7	1.4	3.1	2.6	2.6	2.3	2.6	2.9	2.7	3.0	-1.9	2.4	2.9	2.7	-2.3
Risk taking	5.2	7.6	9.7	-2.8	-1.1	-2.4	-3.1	-3.0	-2.9	-3.1	-2.8	-3.0	-2.8	2.3	-2.6	-3.0	-3.1	2.8
Ever had prostate specific antigen (PSA) test	6.1	7.0	9.4	-2.5	-0.6	-2.3	-2.9	-2.9	-2.9	-1.8	-3.0	-3.0	-3.1	2.8	-1.7	-3.0	-3.0	2.9
Fractured/broken bones in last 5 years	1.0	1.2	2.4	-1.1	-0.4	-0.9	-1.4	-1.3	-1.3	-0.8	-1.6	-1.3	-1.4	-0.2	-0.9	-1.4	-1.2	0.5
Age started oral contraceptive pill	0.8	1.0	4.4	1.8	2.1	0.4	0.7	0.7	0.7	1.2	0.6	0.9	1.0	-0.8	-0.4	0.8	0.7	-0.3
Diastolic blood pressure, automated reading	0.5	1.5	3.6	1.9	-0.2	1.6	1.3	1.3	1.2	1.6	0.9	1.3	1.2	-0.4	0.5	1.3	1.1	-0.8
Ever depressed for a whole week	2.8	3.4	4.7	2.0	-1.1	1.9	2.1	2.1	2.2	0.8	2.1	2.0	2.0	-1.1	1.5	2.1	2.1	-1.8
Unable to work because of sickness or disability	0.2	0.3	3.1	-0.2	-1.8	-0.1	-0.3	-0.3	-0.2	0.2	-0.4	-0.1	-0.1	0.3	0.5	-0.2	-0.4	0.5
Commuting to job workplace: Cycle	0.3	0.4	2.0	0.8	1.4	-0.6	-0.0	-0.1	0.0	0.2	-0.3	-0.1	-0.1	1.2	-0.6	-0.1	-0.1	0.6
Myopia	0.2	0.3	2.0	-1.4	-0.2	-0.3	-0.2	-0.2	-0.1	-0.8	-0.4	-0.3	-0.5	-0.7	0.1	-0.3	-0.2	-0.2
Vascular/heart problems diagnosed by doctor	3.0	8.1	11.4	-2.9	-0.9	-3.1	-3.4	-3.4	-3.3	-0.6	-3.1	-3.2	-3.0	3.0	-0.7	-3.2	-3.4	3.0
Cholesterol lowering medication	6.9	10.1	13.2	3.4	1.6	3.3	3.6	3.5	3.6	2.0	3.6	3.6	3.5	-2.5	2.4	3.5	3.5	-3.0
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	1.9	-0.1	-0.2	0.1	0.4	0.4	0.4	-1.4	0.1	0.0	0.0	-0.2	0.3	0.3	0.2	-0.5
Pain experienced in last month	0.4	0.6	3.4	-0.9	0.8	-0.9	-0.7	-0.7	-0.7	-0.6	-0.7	-0.7	-0.6	0.1	-1.9	-0.6	-0.6	0.4
Supplements: Calcium	0.2	0.2	0.6	0.3	0.3	-0.8	-0.5	-0.5	-0.5	0.6	-0.3	-0.2	-0.1	0.4	-0.0	-0.4	-0.4	0.5
Basal cell carcinoma (self-reported)	0.2	0.2	1.8	1.3	-0.4	-0.4	0.3	0.3	0.6	-0.1	0.4	0.2	0.0	0.4	0.5	0.2	0.3	0.3
Heart attack/myocardial infarction (self-reported)	2.1	2.7	4.0	1.4	0.3	1.5	2.0	2.0	1.9	0.5	1.8	1.9	1.6	-1.5	1.6	1.9	2.0	-1.9
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.5	0.4	-0.5	0.4	0.6	0.6	0.7	0.1	0.7	0.6	0.7	0.5	0.1	0.6	0.5	-0.2
Heart disease (siblings)	0.6	0.7	1.6	1.3	-0.1	0.4	0.8	0.9	0.8	0.7	0.9	0.9	0.8	-1.1	-0.5	0.9	1.0	-0.9
Alcohol drinker status: Previous	0.7	0.8	1.6	-0.3	0.0	-0.7	-1.1	-1.0	-1.2	-0.2	-1.3	-1.0	-1.1	1.0	-0.5	-1.1	-0.9	0.9
Pack years of smoking	1.8	2.6	4.5	1.7	-0.6	1.5	1.9	1.9	1.8	1.1	2.0	1.5	1.5	-0.6	2.1	1.9	1.7	-1.1
Impedance of whole body	1.6	8.3	12.4	-2.4	1.1	-3.5	-3.1	-3.1	-2.7	-2.9	-3.3	-3.1	-2.8	2.2	-3.0	-3.0	-3.2	2.9
Leg fat mass (left)	1.0	3.8	17.6	-2.0	-4.2	-2.1	-1.2	-1.2	-1.5	-2.2	-1.4	-1.8	-1.8	0.6	-2.6	-1.3	-1.4	1.0
Arm predicted mass (left)	1.1	5.6	13.8	-2.3	-3.7	-2.6	-2.1	-2.1	-2.3	-2.3	-2.2	-2.5	-2.7	1.7	-2.0	-2.3	-2.1	1.8