[Hub]/) : Traits : Standing height :

chr6:79,927,081-85,117,025

Best TWAS P=1.47e-49 · Best GWAS P=1.02e-42 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BCKDHB 0.11 0.09 bslmm 563 0.09 1.1e-10 7.7 5.5 3.6e-08 -0.11 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex SNAP91 0.09 0.05 lasso 3 0.08 1.6e-09 6.1 5.6 2.4e-08 0.00 0.65 0.35 TRUE
3 GTEx Adipose Subcutaneous DOPEY1 0.29 0.27 lasso 6 0.28 4.2e-23 6.9 -7.3 2.0e-13 -0.03 0.01 0.99 FALSE
4 GTEx Adipose Visceral Omentum DOPEY1 0.20 0.18 enet 11 0.20 1.1e-10 6.9 -7.3 2.8e-13 0.00 0.01 0.99 FALSE
5 GTEx Adipose Visceral Omentum RP11-250B2.3 0.13 0.00 enet 13 0.01 8.2e-02 -4.8 -5.9 3.5e-09 0.14 0.06 0.05 TRUE
6 GTEx Adipose Visceral Omentum RP11-250B2.6 0.16 0.05 lasso 6 0.06 7.8e-04 11.0 -11.6 4.3e-31 0.00 0.36 0.08 FALSE
7 GTEx Artery Aorta DOPEY1 0.36 0.20 enet 34 0.25 5.4e-14 6.9 -6.0 1.6e-09 -0.03 0.01 0.99 FALSE
8 GTEx Artery Aorta BCKDHB 0.14 0.14 lasso 1 0.13 9.8e-08 7.6 7.6 3.0e-14 -0.03 1.00 0.00 FALSE
9 GTEx Artery Aorta ELOVL4 0.11 0.13 lasso 2 0.11 1.7e-06 5.8 5.8 9.2e-09 0.03 0.95 0.00 FALSE
10 GTEx Artery Coronary BCKDHB 0.29 0.05 lasso 27 0.11 1.7e-04 7.7 5.5 3.0e-08 0.15 0.41 0.04 FALSE
11 GTEx Artery Tibial DOPEY1 0.33 0.28 lasso 7 0.30 2.0e-23 6.9 -7.4 9.8e-14 -0.03 0.01 0.99 FALSE
12 GTEx Artery Tibial BCKDHB 0.16 0.16 lasso 11 0.15 4.9e-12 7.6 7.1 1.2e-12 -0.03 1.00 0.00 FALSE
13 GTEx Brain Caudate basal ganglia UBE3D 0.29 0.28 lasso 2 0.26 5.9e-08 6.8 6.8 9.6e-12 0.05 0.01 0.99 FALSE
14 GTEx Brain Cerebellum RP11-250B2.5 0.43 0.11 lasso 5 0.14 4.7e-05 -11.6 -11.6 4.7e-31 0.17 0.42 0.06 FALSE
15 GTEx Brain Putamen basal ganglia UBE3D 0.40 0.21 lasso 5 0.21 9.5e-06 6.8 6.7 1.8e-11 0.04 0.01 0.96 FALSE
16 GTEx Breast Mammary Tissue DOPEY1 0.32 0.18 enet 29 0.16 1.2e-08 6.9 -6.7 2.2e-11 -0.03 0.01 0.99 FALSE
17 GTEx Breast Mammary Tissue RP11-250B2.3 0.13 0.06 lasso 4 0.04 2.6e-03 -4.8 -5.3 1.2e-07 0.02 0.16 0.06 FALSE
18 GTEx Breast Mammary Tissue (Male) RP11-250B2.6 0.12 0.00 enet 10 0.00 3.9e-01 9.5 6.4 1.9e-10 -0.15 0.06 0.06 FALSE
19 GTEx Breast Mammary Tissue (Female) DOPEY1 0.31 0.14 lasso 5 0.07 4.5e-03 6.9 -6.7 1.7e-11 -0.02 0.02 0.86 FALSE
20 GTEx Breast Mammary Tissue (Female) RP11-250B2.3 0.16 0.06 enet 11 0.04 2.4e-02 10.5 -6.7 2.6e-11 0.01 0.12 0.06 TRUE
21 GTEx Breast Mammary Tissue (Female) RP11-250B2.5 0.08 -0.01 lasso 4 -0.01 7.0e-01 -10.3 -5.3 1.4e-07 0.07 0.06 0.08 FALSE
22 GTEx Cells EBV-transformed lymphocytes RP11-250B2.6 0.21 0.03 enet 37 0.13 4.7e-05 7.7 -8.6 6.5e-18 0.16 0.14 0.05 TRUE
23 GTEx Cells Transformed fibroblasts DOPEY1 0.17 0.14 enet 16 0.17 1.8e-12 6.9 -7.5 5.8e-14 -0.01 0.01 0.99 FALSE
24 GTEx Cells Transformed fibroblasts BCKDHB 0.16 0.02 enet 42 0.04 3.7e-04 8.0 12.3 8.4e-35 -0.09 0.51 0.27 FALSE
25 GTEx Cells Transformed fibroblasts RP11-250B2.5 0.16 0.07 lasso 10 0.05 5.8e-05 12.3 6.9 4.1e-12 -0.05 0.10 0.84 TRUE
26 GTEx Cells Transformed fibroblasts RP11-250B2.6 0.11 0.01 lasso 7 0.00 1.4e-01 -10.8 -7.1 1.0e-12 0.04 0.38 0.02 TRUE
27 GTEx Colon Sigmoid DOPEY1 0.19 0.21 lasso 6 0.21 5.6e-08 7.0 -7.2 4.2e-13 -0.04 0.00 1.00 FALSE
28 GTEx Colon Transverse DOPEY1 0.14 0.13 enet 7 0.12 2.3e-06 6.9 -7.2 4.8e-13 -0.01 0.01 0.98 FALSE
29 GTEx Colon Transverse RP11-250B2.5 0.13 0.02 enet 3 0.01 6.3e-02 -4.8 -8.9 4.0e-19 0.02 0.11 0.08 TRUE
30 GTEx Colon Transverse RP11-250B2.6 0.15 0.16 lasso 2 0.13 9.8e-07 8.0 -7.2 7.3e-13 0.01 0.95 0.00 FALSE
31 GTEx Esophagus Gastroesophageal Junction DOPEY1 0.19 0.11 lasso 5 0.08 6.0e-04 6.9 -7.1 1.0e-12 -0.02 0.01 0.97 FALSE
32 GTEx Esophagus Mucosa RP11-250B2.6 0.20 0.16 lasso 7 0.23 3.3e-15 -10.8 -11.6 4.7e-31 0.02 1.00 0.00 FALSE
33 GTEx Esophagus Muscularis DOPEY1 0.25 0.15 enet 10 0.14 1.4e-08 6.9 -6.3 2.7e-10 -0.02 0.01 0.99 FALSE
34 GTEx Esophagus Muscularis BCKDHB 0.18 0.07 enet 25 0.06 2.4e-04 7.6 7.0 3.6e-12 -0.04 0.94 0.00 FALSE
35 GTEx Heart Atrial Appendage RP11-250B2.6 0.20 0.00 enet 17 0.03 2.6e-02 -7.8 -14.8 1.5e-49 0.26 0.08 0.21 TRUE
36 GTEx Heart Left Ventricle RP11-250B2.6 0.09 0.00 enet 6 0.02 2.0e-02 10.9 -10.7 6.2e-27 0.07 0.16 0.09 FALSE
37 GTEx Lung DOPEY1 0.11 0.13 lasso 3 0.12 2.9e-09 6.9 -6.9 6.8e-12 -0.01 0.01 0.99 FALSE
38 GTEx Lung BCKDHB 0.09 0.06 enet 10 0.05 1.8e-04 7.6 7.6 2.3e-14 -0.03 0.91 0.01 FALSE
39 GTEx Lung UBE3D 0.07 0.01 enet 16 0.02 9.8e-03 6.3 5.2 1.9e-07 0.02 0.06 0.51 FALSE
40 GTEx Lung RP11-250B2.6 0.09 0.05 enet 16 0.07 5.3e-06 8.1 -12.3 1.3e-34 0.01 0.71 0.17 FALSE
41 GTEx Muscle Skeletal DOPEY1 0.13 0.11 lasso 5 0.10 4.2e-10 6.9 -7.2 7.9e-13 -0.02 0.01 0.99 FALSE
42 GTEx Muscle Skeletal RP11-250B2.6 0.07 0.04 lasso 5 0.04 4.2e-05 11.9 -12.5 1.1e-35 0.09 0.81 0.15 FALSE
43 GTEx Nerve Tibial DOPEY1 0.23 0.28 lasso 3 0.28 3.7e-20 6.9 -7.2 8.8e-13 -0.02 0.01 0.99 FALSE
44 GTEx Nerve Tibial BCKDHB 0.18 0.11 lasso 9 0.10 2.4e-07 7.7 7.9 2.3e-15 -0.04 1.00 0.00 FALSE
45 GTEx Ovary DOPEY1 0.33 0.19 enet 18 0.23 2.9e-06 6.9 -7.5 4.7e-14 -0.02 0.01 0.98 FALSE
46 GTEx Skin Not Sun Exposed Suprapubic RP11-250B2.5 0.13 0.16 lasso 4 0.17 1.1e-09 10.5 -6.5 1.1e-10 -0.01 0.98 0.00 FALSE
47 GTEx Skin Not Sun Exposed Suprapubic RP11-250B2.6 0.08 0.05 lasso 4 0.01 8.1e-02 8.1 -6.8 7.3e-12 -0.09 0.22 0.04 FALSE
48 GTEx Skin Sun Exposed Lower leg DOPEY1 0.16 0.17 lasso 5 0.16 4.0e-13 7.0 -7.4 1.2e-13 -0.04 0.00 1.00 FALSE
49 GTEx Spleen DOPEY1 0.21 0.12 lasso 4 0.12 7.1e-04 6.2 -6.6 5.4e-11 -0.04 0.14 0.38 FALSE
50 GTEx Stomach RP11-250B2.6 0.13 0.15 lasso 6 0.12 2.5e-06 8.0 -7.2 5.9e-13 0.00 0.94 0.00 FALSE
51 GTEx Testis DOPEY1 0.19 0.00 lasso 9 0.03 2.4e-02 6.2 -6.4 1.4e-10 -0.03 0.06 0.66 FALSE
52 GTEx Testis ELOVL4 0.31 0.19 lasso 7 0.18 1.9e-08 -6.7 -6.4 1.2e-10 0.09 0.96 0.00 TRUE
53 GTEx Testis RP11-250B2.5 0.13 0.17 lasso 3 0.14 7.0e-07 -10.8 -10.5 1.1e-25 0.06 0.74 0.10 TRUE
54 GTEx Testis RP11-250B2.6 0.09 0.05 lasso 6 0.04 6.9e-03 8.1 -7.4 1.5e-13 0.01 0.42 0.03 FALSE
55 GTEx Thyroid BCKDHB 0.17 0.06 lasso 8 0.10 3.4e-08 8.1 10.1 5.9e-24 -0.05 1.00 0.00 FALSE
56 GTEx Thyroid RP11-250B2.6 0.11 0.10 lasso 2 0.07 3.2e-06 8.0 -8.0 1.2e-15 0.01 1.00 0.00 FALSE
57 METSIM Adipose BCKDHB 0.05 0.03 blup 558 0.05 1.1e-07 -10.8 6.6 4.3e-11 0.00 1.00 0.00 FALSE
58 METSIM Adipose DOPEY1 0.08 0.08 lasso 10 0.07 2.4e-10 6.9 -7.5 5.1e-14 -0.03 0.09 0.91 FALSE
59 METSIM Adipose RP11-250B2.6 0.04 0.04 lasso 12 0.02 1.7e-04 11.5 -9.8 1.8e-22 -0.01 0.74 0.01 FALSE
60 ROSMAP Brain Pre-frontal Cortex DOPEY1 0.11 0.08 enet 45 0.09 2.9e-11 5.6 -5.3 1.4e-07 -0.07 0.91 0.09 FALSE
61 ROSMAP Brain Pre-frontal Cortex BCKDHB 0.18 0.13 lasso 6 0.14 2.9e-17 7.7 6.1 1.1e-09 -0.05 1.00 0.00 FALSE
62 ROSMAP Brain Pre-frontal Cortex FAM46A 0.08 0.01 blup 495 0.03 2.7e-04 5.2 7.3 3.8e-13 0.04 0.65 0.01 TRUE
63 ROSMAP Brain Pre-frontal Cortex RP11-250B2.3 0.08 0.02 blup 402 0.04 5.8e-06 7.5 -6.1 8.1e-10 0.15 0.79 0.02 TRUE
64 YFS Blood DOPEY1 0.18 0.21 lasso 9 0.21 1.4e-67 6.9 -7.4 1.3e-13 -0.02 0.13 0.87 FALSE
65 The Cancer Genome Atlas Breast Invasive Carcinoma DOPEY1 0.05 0.06 lasso 2 0.06 2.6e-12 6.9 -7.2 4.7e-13 -0.02 0.04 0.96 FALSE
66 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BCKDHB 0.12 0.06 lasso 4 0.06 4.2e-07 10.2 -8.1 4.3e-16 0.02 0.97 0.00 TRUE
67 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DOPEY1 0.09 0.02 enet 3 0.04 2.4e-05 6.9 -5.9 4.2e-09 -0.01 0.02 0.97 FALSE
68 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DOPEY1 0.08 0.08 blup 47 0.09 2.3e-10 6.9 -7.6 3.8e-14 -0.04 0.03 0.97 FALSE
69 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ELOVL4 0.09 0.04 enet 4 0.02 1.9e-03 5.5 5.5 3.2e-08 0.00 0.24 0.10 FALSE
70 The Cancer Genome Atlas Liver Hepatocellular Carcinoma DOPEY1 0.06 0.08 lasso 2 0.04 3.9e-03 7.6 -7.7 1.7e-14 -0.04 0.00 0.94 TRUE
71 The Cancer Genome Atlas Lung Adenocarcinoma DOPEY1 0.03 0.02 lasso 2 0.02 2.1e-03 6.9 -7.1 1.2e-12 -0.02 0.02 0.78 FALSE
72 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DOPEY1 0.07 0.05 lasso 3 0.04 8.7e-06 6.9 -6.9 6.8e-12 -0.01 0.10 0.85 FALSE
73 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma DOPEY1 0.08 0.05 blup 47 0.04 1.4e-03 6.9 -6.4 1.3e-10 -0.03 0.02 0.88 FALSE
74 The Cancer Genome Atlas Pancreatic Adenocarcinoma DOPEY1 0.17 0.16 lasso 3 0.14 1.6e-06 6.9 -6.9 6.8e-12 -0.01 0.05 0.93 FALSE
75 The Cancer Genome Atlas Prostate Adenocarcinoma DOPEY1 0.07 0.11 blup 47 0.11 1.7e-11 6.2 -6.7 2.9e-11 -0.04 0.90 0.10 FALSE
76 The Cancer Genome Atlas Soft Tissue Sarcoma DOPEY1 0.04 0.02 blup 47 0.02 1.4e-02 6.0 -6.9 4.0e-12 -0.04 0.01 0.84 FALSE
77 The Cancer Genome Atlas Soft Tissue Sarcoma UBE2CBP 0.09 0.00 blup 85 0.03 6.4e-03 -4.1 5.4 8.5e-08 0.03 0.05 0.28 FALSE
78 The Cancer Genome Atlas Stomach Adenocarcinoma DOPEY1 0.11 0.06 lasso 3 0.06 4.1e-05 6.9 -7.1 1.6e-12 -0.02 0.03 0.95 FALSE
79 The Cancer Genome Atlas Testicular Germ Cell Tumors BCKDHB 0.19 0.02 blup 137 0.06 2.6e-03 7.6 6.2 5.6e-10 -0.04 0.03 0.08 FALSE