Best TWAS P=5.04e-12 · Best GWAS P=5.89e-40 conditioned to 4.37e-36
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C20orf194 | 0.19 | 0.12 | enet | 48 | 0.17 | 9.6e-20 | 5.3 | 5.7 | 1.1e-08 | 0.03 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | PANK2 | 0.11 | 0.00 | enet | 16 | 0.02 | 1.5e-02 | 2.6 | -5.2 | 2.2e-07 | -0.22 | 0.07 | 0.53 | FALSE |
| 3 | GTEx | Artery Tibial | PCNA | 0.18 | 0.12 | lasso | 2 | 0.11 | 8.5e-09 | -6.7 | 6.9 | 5.0e-12 | -0.02 | 0.00 | 1.00 | TRUE |
| 4 | GTEx | Esophagus Muscularis | C20orf194 | 0.19 | 0.10 | enet | 18 | 0.13 | 3.8e-08 | -4.3 | 6.4 | 2.0e-10 | -0.04 | 0.12 | 0.81 | TRUE |
| 5 | GTEx | Nerve Tibial | C20orf194 | 0.14 | 0.10 | lasso | 6 | 0.08 | 4.6e-06 | 5.5 | 5.4 | 5.8e-08 | 0.03 | 0.02 | 0.98 | FALSE |
| 6 | GTEx | Nerve Tibial | PCNA | 0.20 | 0.12 | lasso | 5 | 0.11 | 6.4e-08 | -6.7 | 6.7 | 1.8e-11 | -0.02 | 0.00 | 1.00 | FALSE |
| 7 | GTEx | Thyroid | RNF24 | 0.22 | 0.00 | enet | 45 | 0.02 | 5.9e-03 | -4.4 | -5.3 | 1.0e-07 | -0.10 | 0.34 | 0.08 | FALSE |
| 8 | The Cancer Genome Atlas | Colon Adenocarcinoma | C20orf194 | 0.06 | 0.00 | blup | 97 | 0.03 | 7.5e-03 | 3.6 | 5.8 | 5.6e-09 | -0.02 | 0.03 | 0.82 | FALSE |
| 9 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | C20orf194 | 0.05 | 0.04 | blup | 98 | 0.03 | 6.3e-04 | 5.8 | 6.1 | 8.7e-10 | 0.00 | 0.00 | 0.99 | FALSE |
| 10 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | SMOX | 0.31 | 0.05 | lasso | 5 | 0.07 | 1.3e-03 | -3.7 | -5.6 | 1.7e-08 | -0.30 | 0.05 | 0.05 | TRUE |