Best TWAS P=5.62e-09 · Best GWAS P=1.22e-13 conditioned to 1.23e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | SLMO2 | 0.16 | 0.13 | lasso | 1 | 0.11 | 8.3e-09 | -5.3 | 5.3 | 1.0e-07 | 0.30 | 0.96 | 0.03 | FALSE |
| 2 | NTR | Blood | CTSZ | 0.02 | 0.00 | blup | 562 | 0.01 | 2.2e-03 | 6.0 | -5.8 | 5.6e-09 | -0.36 | 0.11 | 0.03 | TRUE |
| 3 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | ZNF831 | 0.22 | 0.03 | enet | 6 | 0.15 | 9.0e-05 | 6.3 | -5.2 | 2.2e-07 | -0.61 | 0.01 | 0.69 | FALSE |