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chr5:41,211,789-43,890,661

Best TWAS P=3.62e-21 · Best GWAS P=4.69e-30 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCDC152	0.06	0.06	blup	40	0.07	1.6e-08	7.8	-9.4	3.6e-21	0.71	0.74	0.25	TRUE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	GHR	0.12	0.11	enet	6	0.13	2.5e-13	-6.9	-7.7	1.6e-14	-0.04	1.00	0.00	TRUE
10	GTEx	Esophagus Muscularis	CCDC152	0.13	0.09	lasso	8	0.10	7.9e-07	7.9	7.1	1.2e-12	-0.43	0.96	0.00	TRUE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	SEPP1	0.01	0.00	enet	7	0.01	1.5e-03	8.5	-7.1	1.4e-12	0.63	0.04	0.12	TRUE
6	GTEx	Artery Aorta	CCDC152	0.31	0.24	lasso	8	0.24	2.5e-13	8.4	7.0	2.4e-12	-0.42	1.00	0.00	TRUE
14	ROSMAP	Brain Pre-frontal Cortex	CCDC152	0.20	0.09	lasso	10	0.09	5.2e-12	3.1	6.5	8.5e-11	-0.34	1.00	0.00	TRUE
11	GTEx	Nerve Tibial	CCDC152	0.16	0.06	enet	25	0.06	2.9e-05	8.4	5.2	1.8e-07	-0.29	0.93	0.00	TRUE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	SEPP1	0.06	0.02	blup	38	0.04	5.2e-05	7.9	-9.2	5.0e-20	0.74	0.23	0.69	FALSE
17	YFS	Blood	CCDC152	0.07	0.06	enet	16	0.06	2.0e-19	8.6	9.1	1.0e-19	-0.60	1.00	0.00	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCDC152	0.15	0.12	lasso	6	0.12	1.0e-12	8.5	-8.6	7.2e-18	0.56	1.00	0.00	FALSE
12	GTEx	Stomach	SERBP1P6	0.12	0.03	enet	16	0.01	6.7e-02	-5.0	8.6	8.9e-18	-0.38	0.08	0.15	FALSE
4	GTEx	Adipose Subcutaneous	CCDC152	0.09	0.04	lasso	4	0.02	6.4e-03	8.6	8.6	1.1e-17	-0.54	0.84	0.05	FALSE
7	GTEx	Artery Coronary	CCDC152	0.20	0.13	lasso	2	0.12	7.7e-05	8.4	8.5	1.8e-17	-0.56	0.63	0.11	FALSE
13	GTEx	Thyroid	CCDC152	0.10	0.07	lasso	4	0.04	4.2e-04	8.4	8.5	2.0e-17	-0.56	0.74	0.11	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	SEPP1	0.18	0.19	lasso	11	0.21	1.3e-26	7.9	-8.5	2.6e-17	0.55	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	CCDC152	0.09	0.06	lasso	9	0.05	1.9e-03	8.4	8.1	7.0e-16	-0.57	0.16	0.14	FALSE
1	CommonMind	Brain Pre-frontal Cortex	GHR	0.25	0.07	bslmm	382	0.13	2.6e-15	-8.5	7.8	7.2e-15	-0.60	0.02	0.98	FALSE
8	GTEx	Artery Tibial	CCDC152	0.22	0.17	enet	35	0.18	1.8e-14	8.4	7.3	3.3e-13	-0.44	1.00	0.00	FALSE
9	GTEx	Cells Transformed fibroblasts	CTD-2201E18.5	0.06	0.03	enet	10	0.03	1.2e-03	-4.7	-5.6	1.7e-08	0.38	0.54	0.16	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SEPP1	0.06	0.00	blup	330	0.04	1.9e-05	1.3	-5.5	3.8e-08	0.38	0.31	0.23	FALSE
3	CommonMind	Brain Pre-frontal Cortex	ZNF131	0.07	0.02	blup	349	0.02	5.7e-04	1.5	5.4	5.6e-08	-0.53	0.17	0.65	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	C5orf51	0.03	0.01	bslmm	298	0.02	1.9e-03	-4.6	5.3	1.5e-07	-0.14	0.30	0.05	FALSE