[Hub]/) : Traits : Standing height : ← →

chr5:53,702,093-56,923,759

Best TWAS P=1.26e-41 · Best GWAS P=1.32e-39 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
94	The Cancer Genome Atlas	Thyroid Carcinoma	SLC38A9	0.03	0.04	blup	52	0.04	2.0e-04	12.92	13.5	1.3e-41	0.99	0.02	0.98	TRUE
2	CommonMind	Brain Pre-frontal Cortex	DDX4	0.08	0.07	bslmm	390	0.08	1.7e-10	12.60	-12.1	7.1e-34	-0.89	0.03	0.97	TRUE
27	GTEx	Breast Mammary Tissue (Female)	GPX8	0.04	0.00	lasso	2	0.03	5.0e-02	12.61	-11.6	6.3e-31	-0.84	0.05	0.26	TRUE
90	The Cancer Genome Atlas	Skin Cutaneous Melanoma	C5orf35	0.23	0.08	blup	58	0.17	2.5e-05	-8.27	8.8	1.4e-18	-0.04	0.03	0.94	TRUE
29	GTEx	Cells EBV-transformed lymphocytes	PPAP2A	0.22	0.19	lasso	3	0.15	1.4e-05	7.30	-8.3	1.1e-16	-0.36	0.40	0.08	TRUE
7	GTEx	Artery Aorta	SKIV2L2	0.11	0.04	enet	17	0.08	3.4e-05	4.48	-6.2	5.7e-10	-0.45	0.78	0.09	TRUE
88	The Cancer Genome Atlas	Prostate Adenocarcinoma	GZMK	0.04	0.00	blup	40	0.02	7.0e-03	-0.29	-6.2	6.4e-10	-0.19	0.01	0.60	TRUE
1	CommonMind	Brain Pre-frontal Cortex	CCNO	0.06	0.06	enet	12	0.10	1.3e-12	3.94	-5.9	2.8e-09	-0.32	1.00	0.00	TRUE
25	GTEx	Breast Mammary Tissue (Male)	GPX8	0.23	0.01	lasso	8	0.02	9.5e-02	-2.89	-5.4	7.3e-08	-0.18	0.07	0.11	TRUE
67	The Cancer Genome Atlas	Breast Invasive Carcinoma	PPAP2A	0.06	0.03	lasso	1	0.03	1.1e-06	13.12	-13.1	2.5e-39	-0.83	0.00	1.00	FALSE
63	ROSMAP	Brain Pre-frontal Cortex	DDX4	0.07	0.08	lasso	2	0.07	1.5e-09	12.74	-12.9	6.7e-38	-0.86	0.11	0.89	FALSE
14	GTEx	Brain Cerebellum	SLC38A9	0.26	0.13	lasso	4	0.10	7.4e-04	12.85	12.2	4.8e-34	0.88	0.03	0.94	FALSE
77	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SLC38A9	0.04	0.02	enet	7	0.03	6.6e-03	12.37	11.1	1.9e-28	0.83	0.03	0.60	FALSE
17	GTEx	Brain Hippocampus	GZMA	0.32	0.00	lasso	6	0.02	1.3e-01	5.95	9.0	2.4e-19	0.38	0.08	0.19	FALSE
76	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C5orf35	0.27	0.30	lasso	6	0.36	1.4e-21	-6.54	8.1	4.6e-16	0.00	0.96	0.04	FALSE
66	The Cancer Genome Atlas	Breast Invasive Carcinoma	C5orf35	0.29	0.42	lasso	8	0.46	3.0e-107	-6.54	8.0	9.4e-16	-0.01	1.00	0.00	FALSE
95	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	C5orf35	0.38	0.05	blup	58	0.06	7.0e-03	-6.19	8.0	1.1e-15	0.00	0.04	0.71	FALSE
53	GTEx	Testis	SETD9	0.18	0.05	lasso	6	0.11	1.9e-05	-7.43	8.0	1.5e-15	-0.05	0.13	0.82	FALSE
72	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C5orf35	0.24	0.35	lasso	11	0.37	1.9e-43	-6.54	7.9	2.5e-15	0.00	1.00	0.00	FALSE
50	GTEx	Stomach	SETD9	0.35	0.31	lasso	8	0.38	1.9e-19	-6.54	7.9	2.6e-15	-0.02	0.82	0.18	FALSE
21	GTEx	Brain Putamen basal ganglia	SETD9	0.23	0.15	lasso	3	0.14	2.9e-04	-7.24	7.9	2.8e-15	-0.05	0.07	0.70	FALSE
26	GTEx	Breast Mammary Tissue (Female)	SETD9	0.21	0.12	lasso	11	0.16	1.4e-05	-7.42	7.8	4.8e-15	0.01	0.09	0.85	FALSE
74	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C5orf35	0.35	0.46	lasso	5	0.48	7.8e-62	-6.54	7.8	5.4e-15	-0.01	1.00	0.00	FALSE
31	GTEx	Cells Transformed fibroblasts	SETD9	0.31	0.42	lasso	6	0.47	5.7e-39	-6.54	7.8	6.6e-15	-0.01	1.00	0.00	FALSE
85	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	C5orf35	0.33	0.35	enet	22	0.36	4.9e-16	-6.54	7.8	8.3e-15	-0.01	0.95	0.05	FALSE
5	GTEx	Adipose Visceral Omentum	SETD9	0.16	0.20	lasso	8	0.16	6.8e-09	-6.54	7.7	1.1e-14	0.01	0.55	0.45	FALSE
33	GTEx	Colon Transverse	SETD9	0.47	0.42	lasso	10	0.43	4.0e-22	-6.54	7.7	1.1e-14	0.00	0.99	0.01	FALSE
35	GTEx	Esophagus Mucosa	SETD9	0.47	0.55	lasso	9	0.58	1.3e-47	-6.54	7.7	1.1e-14	-0.01	1.00	0.00	FALSE
56	GTEx	Uterus	SETD9	0.31	0.15	lasso	8	0.19	1.2e-04	-6.54	7.7	1.2e-14	0.02	0.20	0.32	FALSE
65	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C5orf35	0.21	0.28	lasso	7	0.31	8.0e-27	-6.54	7.7	1.2e-14	0.00	1.00	0.00	FALSE
80	The Cancer Genome Atlas	Lung Adenocarcinoma	C5orf35	0.42	0.45	enet	17	0.50	3.2e-67	-6.54	7.7	1.2e-14	0.02	1.00	0.00	FALSE
79	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	C5orf35	0.23	0.39	lasso	11	0.37	1.9e-18	-7.43	7.7	1.3e-14	-0.09	0.90	0.10	FALSE
6	GTEx	Adrenal Gland	SETD9	0.39	0.29	lasso	8	0.35	1.6e-13	-6.54	7.7	1.4e-14	-0.03	0.86	0.14	FALSE
68	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	C5orf35	0.30	0.35	lasso	8	0.40	5.3e-21	-7.44	7.7	1.4e-14	-0.04	0.94	0.06	FALSE
82	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	C5orf35	0.21	0.29	lasso	11	0.33	1.3e-38	-6.54	7.7	1.9e-14	-0.02	1.00	0.00	FALSE
40	GTEx	Muscle Skeletal	SETD9	0.33	0.42	enet	32	0.44	1.3e-46	-6.54	7.6	2.0e-14	0.01	1.00	0.00	FALSE
93	The Cancer Genome Atlas	Thyroid Carcinoma	C5orf35	0.46	0.61	lasso	14	0.63	1.5e-79	-6.54	7.6	2.6e-14	-0.01	1.00	0.00	FALSE
38	GTEx	Heart Left Ventricle	SETD9	0.42	0.39	enet	12	0.39	5.8e-22	-6.54	7.6	2.9e-14	-0.01	1.00	0.00	FALSE
47	GTEx	Skin Sun Exposed Lower leg	SETD9	0.40	0.44	lasso	15	0.46	1.8e-42	-6.54	7.6	3.0e-14	0.00	1.00	0.00	FALSE
91	The Cancer Genome Atlas	Stomach Adenocarcinoma	C5orf35	0.32	0.40	enet	19	0.44	4.8e-35	-6.54	7.6	3.2e-14	-0.01	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	SETD9	0.15	0.14	lasso	10	0.16	3.0e-13	-7.02	7.6	3.3e-14	0.01	0.98	0.02	FALSE
59	GTEx	Whole Blood	SETD9	0.16	0.26	lasso	7	0.27	1.6e-24	-7.43	7.6	3.7e-14	-0.06	0.93	0.07	FALSE
23	GTEx	Breast Mammary Tissue	GPX8	0.06	0.00	lasso	4	0.01	1.6e-01	5.10	-7.6	4.2e-14	-0.56	0.16	0.32	FALSE
89	The Cancer Genome Atlas	Soft Tissue Sarcoma	C5orf35	0.23	0.24	blup	58	0.25	3.8e-15	-7.43	7.6	4.2e-14	-0.05	0.91	0.09	FALSE
70	The Cancer Genome Atlas	Esophageal Carcinoma	C5orf35	0.19	0.20	lasso	4	0.18	1.9e-06	-7.43	7.5	4.4e-14	-0.08	0.38	0.54	FALSE
78	The Cancer Genome Atlas	Brain Lower Grade Glioma	C5orf35	0.28	0.39	lasso	5	0.40	2.1e-48	-6.54	7.5	4.5e-14	-0.01	1.00	0.00	FALSE
9	GTEx	Artery Coronary	SETD9	0.46	0.40	lasso	7	0.50	4.3e-19	-6.54	7.5	5.2e-14	-0.03	0.95	0.05	FALSE
20	GTEx	Brain Nucleus accumbens basal ganglia	SETD9	0.30	0.33	lasso	3	0.32	3.7e-09	-6.54	7.5	7.5e-14	0.01	0.56	0.34	FALSE
64	ROSMAP	Brain Pre-frontal Cortex	SETD9	0.27	0.39	lasso	8	0.42	3.4e-59	-6.54	7.5	7.7e-14	-0.01	1.00	0.00	FALSE
87	The Cancer Genome Atlas	Prostate Adenocarcinoma	C5orf35	0.44	0.58	lasso	9	0.60	1.4e-78	-6.54	7.5	7.7e-14	0.00	1.00	0.00	FALSE
39	GTEx	Lung	SETD9	0.33	0.41	lasso	7	0.41	5.8e-34	-6.54	7.5	8.4e-14	-0.01	1.00	0.00	FALSE
22	GTEx	Breast Mammary Tissue	SETD9	0.30	0.38	lasso	4	0.38	8.2e-21	-6.54	7.4	9.7e-14	0.01	1.00	0.00	FALSE
42	GTEx	Ovary	SETD9	0.35	0.29	enet	17	0.28	1.1e-07	-6.54	7.4	1.0e-13	-0.03	0.29	0.50	FALSE
60	METSIM	Adipose	SETD9	0.10	0.14	lasso	17	0.16	9.6e-23	-7.43	7.4	1.1e-13	-0.05	0.94	0.06	FALSE
69	The Cancer Genome Atlas	Colon Adenocarcinoma	C5orf35	0.45	0.50	lasso	6	0.52	1.8e-34	-6.54	7.4	2.0e-13	0.00	1.00	0.00	FALSE
36	GTEx	Esophagus Muscularis	SETD9	0.46	0.51	lasso	5	0.52	2.7e-36	-6.54	7.3	3.3e-13	-0.02	1.00	0.00	FALSE
32	GTEx	Colon Sigmoid	SETD9	0.49	0.49	lasso	14	0.53	7.9e-22	-5.88	7.3	3.4e-13	0.01	0.99	0.01	FALSE
83	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C5orf35	0.27	0.26	lasso	3	0.28	9.3e-19	-6.36	7.3	3.7e-13	-0.01	1.00	0.00	FALSE
46	GTEx	Skin Not Sun Exposed Suprapubic	SETD9	0.51	0.56	lasso	9	0.58	1.9e-38	-6.54	7.2	4.2e-13	0.00	1.00	0.00	FALSE
86	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C5orf35	0.50	0.49	lasso	10	0.56	4.1e-26	-6.54	7.2	4.7e-13	-0.02	0.99	0.01	FALSE
55	GTEx	Thyroid	SETD9	0.38	0.41	lasso	4	0.42	9.7e-35	-6.54	7.2	5.3e-13	0.00	1.00	0.00	FALSE
41	GTEx	Nerve Tibial	SETD9	0.41	0.46	enet	24	0.47	3.3e-37	-6.54	7.2	5.7e-13	-0.01	1.00	0.00	FALSE
54	GTEx	Testis	CTD-2310F14.1	0.35	0.14	lasso	8	0.15	2.9e-07	-5.88	-7.1	8.8e-13	0.06	0.23	0.75	FALSE
8	GTEx	Artery Aorta	SETD9	0.51	0.55	lasso	3	0.56	8.8e-37	-6.54	7.1	1.5e-12	0.02	1.00	0.00	FALSE
71	The Cancer Genome Atlas	Glioblastoma Multiforme	C5orf35	0.49	0.49	lasso	7	0.50	1.5e-17	-6.54	7.1	1.5e-12	0.03	0.99	0.01	FALSE
13	GTEx	Brain Cerebellum	SETD9	0.44	0.25	enet	21	0.34	1.1e-10	-6.54	7.0	2.2e-12	0.02	0.94	0.04	FALSE
57	GTEx	Vagina	SETD9	0.44	0.52	lasso	3	0.49	4.8e-13	-6.54	7.0	2.4e-12	0.02	0.85	0.13	FALSE
24	GTEx	Breast Mammary Tissue (Male)	SETD9	0.42	0.37	lasso	4	0.33	1.9e-08	-6.54	6.9	3.7e-12	0.02	0.84	0.07	FALSE
43	GTEx	Pancreas	SETD9	0.43	0.51	lasso	9	0.49	1.7e-23	-6.54	6.9	4.1e-12	0.02	1.00	0.00	FALSE
92	The Cancer Genome Atlas	Testicular Germ Cell Tumors	C5orf35	0.31	0.23	lasso	8	0.29	8.9e-11	-6.54	6.9	4.8e-12	0.00	0.65	0.35	FALSE
11	GTEx	Brain Caudate basal ganglia	SETD9	0.31	0.28	lasso	6	0.26	5.0e-08	-5.90	6.9	4.9e-12	0.00	0.93	0.05	FALSE
37	GTEx	Heart Atrial Appendage	SETD9	0.29	0.36	lasso	3	0.35	2.1e-16	-6.54	6.9	5.1e-12	0.01	1.00	0.00	FALSE
30	GTEx	Cells EBV-transformed lymphocytes	SETD9	0.44	0.25	enet	27	0.37	4.0e-13	-7.01	6.8	7.5e-12	-0.02	0.98	0.02	FALSE
48	GTEx	Spleen	SETD9	0.38	0.24	lasso	3	0.22	2.7e-06	-6.54	6.8	8.1e-12	0.03	0.78	0.05	FALSE
34	GTEx	Esophagus Gastroesophageal Junction	SETD9	0.35	0.47	lasso	3	0.45	7.0e-18	-6.54	6.8	9.1e-12	0.01	1.00	0.00	FALSE
12	GTEx	Brain Cerebellar Hemisphere	SETD9	0.31	0.36	lasso	9	0.32	4.2e-09	-6.42	6.8	1.3e-11	0.03	0.90	0.05	FALSE
10	GTEx	Artery Tibial	SETD9	0.47	0.54	lasso	4	0.53	9.4e-49	-6.54	6.8	1.4e-11	0.02	1.00	0.00	FALSE
28	GTEx	Breast Mammary Tissue (Female)	CTD-2310F14.1	0.21	0.01	lasso	6	0.02	9.4e-02	4.95	-6.7	2.3e-11	0.04	0.04	0.65	FALSE
45	GTEx	Prostate	SETD9	0.36	0.26	lasso	6	0.23	1.7e-06	-6.36	6.7	2.4e-11	0.03	0.73	0.09	FALSE
15	GTEx	Brain Cortex	SETD9	0.43	0.36	lasso	6	0.27	4.5e-08	-6.54	6.6	3.2e-11	0.02	0.81	0.14	FALSE
73	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCNO	0.03	0.02	enet	3	0.02	1.4e-03	6.09	-6.6	4.7e-11	-0.33	0.12	0.08	FALSE
18	GTEx	Brain Hippocampus	SETD9	0.42	0.41	lasso	5	0.39	3.8e-10	-6.54	6.4	1.3e-10	0.02	0.78	0.12	FALSE
44	GTEx	Pituitary	SETD9	0.38	0.29	lasso	13	0.28	1.3e-07	-6.54	6.3	2.4e-10	0.03	0.64	0.04	FALSE
16	GTEx	Brain Frontal Cortex BA9	SETD9	0.20	0.15	enet	13	0.10	1.0e-03	-6.54	6.3	2.5e-10	0.01	0.18	0.24	FALSE
58	GTEx	Vagina	CTD-2310F14.1	0.33	0.02	lasso	7	0.01	1.7e-01	-5.84	6.3	4.0e-10	0.05	0.10	0.07	FALSE
81	The Cancer Genome Atlas	Lung Adenocarcinoma	MAP3K1	0.02	0.01	blup	83	0.01	9.1e-03	-2.24	-6.2	5.9e-10	-0.04	0.04	0.55	FALSE
4	GTEx	Adipose Subcutaneous	SLC38A9	0.11	0.00	enet	24	0.00	6.5e-01	12.70	-6.2	7.5e-10	-0.41	0.05	0.12	FALSE
62	NTR	Blood	C5orf35	0.01	0.01	bslmm	497	0.00	2.1e-02	-5.85	6.1	1.2e-09	0.02	0.43	0.22	FALSE
75	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPAP2A	0.14	0.00	blup	58	0.03	4.4e-04	13.12	-6.0	2.6e-09	-0.49	0.00	0.94	FALSE
52	GTEx	Testis	GZMA	0.10	0.04	lasso	7	0.03	1.4e-02	4.51	5.9	3.9e-09	0.30	0.35	0.06	FALSE
19	GTEx	Brain Hypothalamus	SETD9	0.36	0.31	enet	16	0.35	5.0e-09	-6.54	5.8	6.4e-09	-0.07	0.58	0.20	FALSE
51	GTEx	Testis	SKIV2L2	0.24	0.14	lasso	5	0.12	8.1e-06	6.03	5.6	1.6e-08	0.36	0.80	0.05	FALSE
49	GTEx	Spleen	CTD-2310F14.1	0.38	0.00	enet	21	0.01	2.0e-01	-8.04	-5.6	1.7e-08	0.08	0.05	0.45	FALSE
61	NTR	Blood	ANKRD55	0.05	0.01	enet	31	0.02	5.4e-08	0.90	-5.4	6.3e-08	-0.39	0.19	0.79	FALSE
84	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	DHX29	0.04	0.03	lasso	2	0.02	2.3e-02	5.00	5.3	1.5e-07	0.45	0.20	0.05	FALSE