[Hub]/) : Traits : Qualifications: College or University degree :

chr1:92,924,057-94,534,354

Best TWAS P=1.74e-17 · Best GWAS P=5.67e-18 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DR1 0.21 0.20 blup 305 0.23 1.8e-27 -8.6 -7.2 5.0e-13 0.85 0.01 0.99 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC100131564 0.39 0.53 bslmm 315 0.54 9.6e-78 -5.3 5.8 5.7e-09 -0.74 1.00 0.00 FALSE
3 CommonMind Brain Pre-frontal Cortex TMED5 0.06 0.07 enet 20 0.09 6.7e-11 -7.2 8.4 6.0e-17 -0.93 0.02 0.98 FALSE
4 GTEx Adipose Subcutaneous DR1 0.18 0.14 lasso 6 0.12 3.7e-10 -5.4 -6.2 6.6e-10 0.76 0.98 0.02 FALSE
5 GTEx Adipose Subcutaneous RP4-717I23.3 0.34 0.39 lasso 7 0.44 2.5e-39 -5.3 5.3 1.4e-07 -0.66 1.00 0.00 FALSE
6 GTEx Adipose Visceral Omentum DR1 0.10 0.05 lasso 5 0.06 5.0e-04 -6.7 -6.9 4.6e-12 0.84 0.11 0.87 FALSE
7 GTEx Adipose Visceral Omentum RP4-717I23.3 0.28 0.32 enet 19 0.34 1.4e-18 -5.3 6.1 1.0e-09 -0.74 1.00 0.00 FALSE
8 GTEx Artery Aorta DR1 0.15 0.10 lasso 5 0.14 3.1e-08 -5.3 -6.8 1.3e-11 0.85 0.18 0.82 FALSE
9 GTEx Artery Aorta RP4-717I23.3 0.26 0.36 lasso 5 0.33 4.6e-19 -5.3 5.4 7.0e-08 -0.67 1.00 0.00 FALSE
10 GTEx Artery Coronary RP4-717I23.3 0.14 0.17 lasso 5 0.17 3.1e-06 -5.3 5.3 1.1e-07 -0.66 0.45 0.45 FALSE
11 GTEx Artery Tibial DR1 0.17 0.11 lasso 8 0.18 5.9e-14 -8.6 -7.5 8.5e-14 0.90 0.03 0.97 FALSE
12 GTEx Artery Tibial RP4-717I23.3 0.22 0.32 lasso 11 0.36 9.0e-30 -5.3 5.9 3.5e-09 -0.75 1.00 0.00 FALSE
13 GTEx Brain Caudate basal ganglia RP4-717I23.3 0.43 0.46 enet 24 0.48 9.2e-16 -5.3 5.4 6.2e-08 -0.68 0.99 0.01 FALSE
14 GTEx Brain Cerebellar Hemisphere TMED5 0.37 0.06 enet 21 0.11 1.1e-03 -7.7 6.8 1.4e-11 -0.87 0.02 0.93 FALSE
15 GTEx Brain Cerebellar Hemisphere RP4-717I23.3 0.44 0.40 lasso 6 0.48 5.8e-14 -5.0 6.2 6.7e-10 -0.79 0.39 0.61 FALSE
16 GTEx Brain Cerebellum DR1 0.17 0.10 enet 23 0.12 2.2e-04 -5.3 -6.1 1.3e-09 0.67 0.17 0.37 FALSE
17 GTEx Brain Cerebellum RP4-717I23.3 0.48 0.53 enet 32 0.57 2.9e-20 -5.3 6.8 1.0e-11 -0.83 0.68 0.32 FALSE
18 GTEx Brain Cortex RP4-717I23.3 0.39 0.37 enet 19 0.42 1.0e-12 -5.2 5.5 4.6e-08 -0.69 0.91 0.09 FALSE
19 GTEx Brain Frontal Cortex BA9 RP4-717I23.3 0.48 0.53 lasso 12 0.53 1.6e-16 -5.3 5.5 2.9e-08 -0.70 0.74 0.26 FALSE
20 GTEx Brain Hippocampus RP4-717I23.3 0.28 0.24 lasso 7 0.22 8.0e-06 -5.3 5.3 1.0e-07 -0.66 0.40 0.52 FALSE
21 GTEx Brain Hypothalamus RP4-717I23.3 0.33 0.35 enet 25 0.37 1.1e-09 -5.2 5.5 4.4e-08 -0.69 0.55 0.44 FALSE
22 GTEx Brain Nucleus accumbens basal ganglia RP4-717I23.3 0.50 0.42 lasso 5 0.47 3.0e-14 -5.3 5.5 3.5e-08 -0.69 0.96 0.04 FALSE
23 GTEx Brain Putamen basal ganglia RP4-717I23.3 0.38 0.34 enet 37 0.34 9.1e-09 -5.3 5.6 2.6e-08 -0.72 0.52 0.44 FALSE
24 GTEx Breast Mammary Tissue RP4-717I23.3 0.30 0.32 enet 17 0.33 1.4e-17 -5.3 5.5 4.3e-08 -0.66 1.00 0.00 FALSE
25 GTEx Breast Mammary Tissue (Male) RP4-717I23.3 0.29 0.23 lasso 8 0.21 1.5e-05 -5.3 5.3 9.8e-08 -0.65 0.36 0.14 FALSE
26 GTEx Breast Mammary Tissue (Female) RP4-717I23.3 0.19 0.20 lasso 13 0.19 2.1e-06 -5.3 5.3 1.4e-07 -0.66 0.79 0.12 FALSE
27 GTEx Cells EBV-transformed lymphocytes RP4-717I23.3 0.32 0.36 lasso 10 0.36 9.8e-13 -5.3 5.7 1.3e-08 -0.71 0.97 0.03 FALSE
28 GTEx Cells Transformed fibroblasts TMED5 0.10 0.11 lasso 3 0.09 4.6e-07 -8.6 7.9 2.5e-15 -0.96 0.02 0.98 FALSE
29 GTEx Cells Transformed fibroblasts DR1 0.18 0.21 enet 18 0.24 6.0e-18 -5.4 -7.0 2.4e-12 0.82 0.96 0.04 FALSE
30 GTEx Cells Transformed fibroblasts RP4-717I23.3 0.25 0.30 lasso 3 0.33 3.8e-25 -5.0 5.2 1.9e-07 -0.66 1.00 0.00 FALSE
31 GTEx Colon Sigmoid RP4-717I23.3 0.28 0.30 lasso 8 0.33 2.4e-12 -5.3 6.3 3.8e-10 -0.75 0.85 0.15 FALSE
32 GTEx Colon Transverse DR1 0.14 0.14 lasso 5 0.10 1.7e-05 -5.3 -5.8 5.8e-09 0.73 0.23 0.75 FALSE
33 GTEx Colon Transverse CCDC18 0.10 0.04 enet 11 0.04 8.0e-03 -4.1 6.3 3.5e-10 -0.63 0.22 0.59 FALSE
34 GTEx Colon Transverse RP4-717I23.3 0.25 0.28 lasso 5 0.23 2.0e-11 -5.3 5.3 1.1e-07 -0.66 1.00 0.00 FALSE
35 GTEx Esophagus Gastroesophageal Junction RP4-717I23.3 0.31 0.26 lasso 17 0.30 1.4e-11 -5.3 6.5 6.4e-11 -0.84 0.16 0.84 FALSE
36 GTEx Esophagus Mucosa RP4-717I23.3 0.23 0.27 lasso 2 0.29 1.5e-19 -5.2 5.3 1.4e-07 -0.64 1.00 0.00 FALSE
37 GTEx Esophagus Muscularis DR1 0.12 0.06 lasso 7 0.07 6.6e-05 -5.3 -5.8 6.1e-09 0.74 0.36 0.40 FALSE
38 GTEx Esophagus Muscularis CCDC18 0.06 0.05 lasso 4 0.04 2.8e-03 -6.7 6.5 6.8e-11 -0.78 0.09 0.84 FALSE
39 GTEx Esophagus Muscularis RP4-717I23.3 0.31 0.38 lasso 5 0.42 2.0e-27 -5.3 6.4 1.4e-10 -0.78 1.00 0.00 FALSE
40 GTEx Heart Atrial Appendage DR1 0.10 0.06 lasso 4 0.05 2.8e-03 -7.2 -5.9 4.6e-09 0.74 0.20 0.60 FALSE
41 GTEx Heart Atrial Appendage RP4-717I23.3 0.30 0.25 lasso 6 0.27 1.3e-12 -5.3 5.3 9.2e-08 -0.66 1.00 0.00 FALSE
42 GTEx Heart Left Ventricle RP4-717I23.3 0.20 0.25 lasso 5 0.26 3.1e-14 -5.3 5.3 1.2e-07 -0.66 1.00 0.00 FALSE
43 GTEx Liver RP4-717I23.3 0.22 0.21 lasso 8 0.16 3.6e-05 -5.3 5.1 2.8e-07 -0.63 0.63 0.04 FALSE
44 GTEx Lung DR1 0.07 0.07 lasso 4 0.06 2.4e-05 -5.2 -5.7 1.4e-08 0.72 0.81 0.16 FALSE
45 GTEx Lung RP4-717I23.3 0.38 0.36 lasso 9 0.36 3.9e-29 -5.3 5.3 1.1e-07 -0.66 1.00 0.00 FALSE
46 GTEx Nerve Tibial DR1 0.10 0.08 lasso 4 0.07 8.8e-06 -5.4 -5.8 7.4e-09 0.69 0.71 0.27 FALSE
47 GTEx Nerve Tibial CCDC18 0.06 0.04 lasso 11 0.04 7.2e-04 -7.2 6.7 1.7e-11 -0.85 0.04 0.92 FALSE
48 GTEx Nerve Tibial RP4-717I23.3 0.43 0.46 enet 39 0.54 1.0e-44 -5.4 6.5 6.0e-11 -0.77 1.00 0.00 FALSE
49 GTEx Ovary RP4-717I23.3 0.44 0.43 lasso 7 0.42 1.5e-11 -5.3 5.3 1.1e-07 -0.65 0.96 0.03 FALSE
50 GTEx Pancreas RP4-717I23.3 0.28 0.32 lasso 8 0.32 4.0e-14 -5.3 5.3 9.1e-08 -0.66 1.00 0.00 FALSE
51 GTEx Pituitary RP4-717I23.3 0.53 0.44 lasso 11 0.47 1.8e-13 -5.3 6.0 1.9e-09 -0.74 0.87 0.13 FALSE
52 GTEx Prostate RP4-717I23.3 0.46 0.46 lasso 10 0.45 1.1e-12 -5.2 5.3 1.2e-07 -0.64 0.88 0.12 FALSE
53 GTEx Skin Not Sun Exposed Suprapubic RP4-717I23.3 0.40 0.41 lasso 9 0.38 3.7e-22 -5.3 5.3 1.4e-07 -0.65 1.00 0.00 FALSE
54 GTEx Spleen CCDC18 0.29 0.07 lasso 10 0.15 9.2e-05 -8.6 8.2 2.1e-16 -0.91 0.03 0.93 FALSE
55 GTEx Spleen RP4-717I23.3 0.39 0.46 enet 22 0.48 5.3e-14 -5.0 5.2 2.4e-07 -0.66 0.99 0.01 FALSE
56 GTEx Stomach RP4-717I23.3 0.33 0.35 lasso 8 0.38 2.5e-19 -5.3 5.8 6.4e-09 -0.75 0.99 0.01 FALSE
57 GTEx Testis TMED5 0.27 0.31 lasso 5 0.30 6.9e-14 -8.6 8.5 1.7e-17 -0.99 0.01 0.99 TRUE
58 GTEx Thyroid RP4-717I23.3 0.41 0.44 lasso 10 0.49 1.8e-42 -5.3 5.6 2.6e-08 -0.69 1.00 0.00 FALSE
59 GTEx Uterus RP4-717I23.3 0.23 0.16 enet 14 0.17 2.7e-04 -5.3 5.5 2.9e-08 -0.65 0.23 0.32 FALSE
60 GTEx Vagina RP4-717I23.3 0.26 0.13 lasso 7 0.09 3.8e-03 -5.3 5.6 1.9e-08 -0.67 0.12 0.53 FALSE
61 METSIM Adipose CCDC18 0.08 0.06 lasso 4 0.07 4.9e-10 -5.2 6.7 2.3e-11 -0.77 0.98 0.02 FALSE
62 METSIM Adipose DR1 0.04 0.04 lasso 3 0.04 1.0e-06 -5.0 -5.2 1.5e-07 0.65 0.97 0.02 FALSE
63 METSIM Adipose RP4-717I23.3 0.21 0.34 enet 34 0.34 3.0e-52 -5.0 5.4 7.6e-08 -0.67 1.00 0.00 FALSE
64 METSIM Adipose TMED5 0.05 0.07 lasso 17 0.06 2.4e-09 -5.3 5.3 9.7e-08 -0.66 1.00 0.00 FALSE
65 NTR Blood TMED5 0.01 0.01 blup 277 0.01 5.2e-04 -7.2 7.0 2.3e-12 -0.83 0.02 0.97 FALSE
66 ROSMAP Brain Pre-frontal Cortex TMED5 0.11 0.10 enet 17 0.13 2.7e-16 -7.2 7.4 1.6e-13 -0.86 0.02 0.98 FALSE
67 ROSMAP Brain Pre-frontal Cortex DR1 0.09 0.12 enet 20 0.16 1.2e-20 -5.3 -6.8 8.8e-12 0.88 0.34 0.66 FALSE
68 ROSMAP Brain Pre-frontal Cortex RP4-717I23.3 0.33 0.57 lasso 9 0.58 2.6e-92 -5.3 5.7 9.7e-09 -0.71 1.00 0.00 FALSE
69 YFS Blood DR1 0.11 0.17 lasso 17 0.19 2.0e-58 -7.7 -8.2 2.1e-16 0.94 0.03 0.97 FALSE
70 YFS Blood TMED5 0.14 0.19 lasso 16 0.22 1.1e-69 -5.3 7.0 2.3e-12 -0.88 1.00 0.00 FALSE
71 The Cancer Genome Atlas Breast Invasive Carcinoma DR1 0.04 0.04 lasso 3 0.04 1.5e-08 -7.7 -7.9 3.3e-15 0.96 0.02 0.98 FALSE
72 The Cancer Genome Atlas Breast Invasive Carcinoma TMED5 0.06 0.00 enet 7 0.01 2.5e-02 3.8 6.6 4.1e-11 -0.62 0.02 0.40 FALSE
73 The Cancer Genome Atlas Colon Adenocarcinoma CCDC18 0.08 0.08 lasso 1 0.05 7.7e-04 -5.3 -5.3 1.1e-07 0.67 0.40 0.13 FALSE
74 The Cancer Genome Atlas Colon Adenocarcinoma DR1 0.36 0.06 enet 9 0.06 2.2e-04 -7.2 -5.3 1.1e-07 0.66 0.07 0.57 FALSE
75 The Cancer Genome Atlas Glioblastoma Multiforme TMED5 0.08 0.05 blup 39 0.03 4.7e-02 -8.6 8.3 1.1e-16 -0.99 0.01 0.73 FALSE
76 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DR1 0.03 0.03 lasso 1 0.03 3.2e-04 -7.2 -7.2 6.2e-13 0.81 0.02 0.64 FALSE
77 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DR1 0.05 0.05 blup 29 0.06 4.1e-07 -8.6 -8.3 9.8e-17 0.97 0.00 1.00 FALSE
78 The Cancer Genome Atlas Brain Lower Grade Glioma CCDC18 0.03 0.03 blup 52 0.03 5.0e-04 -4.1 7.0 2.1e-12 -0.76 0.04 0.67 FALSE
79 The Cancer Genome Atlas Brain Lower Grade Glioma DR1 0.03 0.03 blup 29 0.03 1.1e-04 -7.6 -7.9 2.0e-15 0.97 0.01 0.98 FALSE
80 The Cancer Genome Atlas Brain Lower Grade Glioma TMED5 0.08 0.06 enet 12 0.07 3.5e-08 -8.6 8.5 2.2e-17 -0.86 0.01 0.99 FALSE
81 The Cancer Genome Atlas Lung Adenocarcinoma DR1 0.05 0.03 blup 29 0.03 1.3e-04 -7.2 -8.2 3.5e-16 0.89 0.01 0.92 FALSE
82 The Cancer Genome Atlas Lung Squamous Cell Carcinoma DR1 0.03 0.02 blup 29 0.02 3.2e-03 -8.6 -8.3 1.1e-16 0.98 0.00 0.96 FALSE
83 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TMED5 0.05 0.05 enet 11 0.04 9.7e-04 -6.6 7.1 1.2e-12 -0.86 0.02 0.84 FALSE
84 The Cancer Genome Atlas Pancreatic Adenocarcinoma DR1 0.09 0.09 lasso 2 0.07 4.7e-04 -7.7 -7.7 1.8e-14 0.96 0.01 0.76 FALSE
85 The Cancer Genome Atlas Prostate Adenocarcinoma DR1 0.10 0.09 blup 29 0.08 3.9e-09 -7.6 -8.2 3.0e-16 0.96 0.01 0.99 FALSE
86 The Cancer Genome Atlas Soft Tissue Sarcoma DR1 0.10 0.03 lasso 4 0.06 3.2e-04 -5.3 -7.4 1.5e-13 0.88 0.01 0.97 FALSE
87 The Cancer Genome Atlas Stomach Adenocarcinoma DR1 0.07 0.05 enet 9 0.07 6.2e-06 -8.6 -7.7 1.7e-14 0.93 0.01 0.99 FALSE
88 The Cancer Genome Atlas Stomach Adenocarcinoma TMED5 0.05 0.06 lasso 2 0.05 1.4e-04 -7.2 7.2 4.3e-13 -0.95 0.02 0.94 FALSE
89 The Cancer Genome Atlas Thyroid Carcinoma DR1 0.16 0.18 blup 29 0.19 4.1e-18 -8.6 -8.3 6.6e-17 0.96 0.00 1.00 FALSE