[Hub]/) : Traits : Qualifications: College or University degree :

chr1:109,316,076-110,742,615

Best TWAS P=1.17e-09 · Best GWAS P=5.54e-09 conditioned to 1.52e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellar Hemisphere SYPL2 0.28 0.04 lasso 5 0.09 2.7e-03 5.5 6.1 1.2e-09 0.03 0.03 0.95 TRUE
2 GTEx Brain Cerebellum SYPL2 0.16 0.02 enet 9 0.03 5.1e-02 5.4 5.5 3.6e-08 0.03 0.03 0.91 FALSE
3 GTEx Liver SYPL2 0.34 0.27 lasso 5 0.30 4.6e-09 5.5 5.6 2.5e-08 0.02 0.03 0.97 FALSE
4 GTEx Muscle Skeletal CYB561D1 0.07 0.00 lasso 3 0.00 7.2e-01 5.1 -5.2 2.0e-07 -0.01 0.05 0.83 FALSE
5 GTEx Ovary SYPL2 0.39 0.44 lasso 5 0.46 8.8e-13 5.1 -5.5 4.9e-08 -0.02 0.03 0.97 FALSE
6 GTEx Ovary ATXN7L2 0.18 0.18 enet 17 0.13 5.6e-04 5.2 -5.4 8.4e-08 -0.02 0.04 0.91 FALSE
7 GTEx Testis SYPL2 0.45 0.50 enet 22 0.54 5.0e-28 5.4 -5.5 3.8e-08 -0.02 0.04 0.96 FALSE
8 GTEx Testis ATXN7L2 0.28 0.34 lasso 4 0.33 3.7e-15 5.3 -5.3 1.1e-07 -0.02 0.04 0.96 FALSE
9 The Cancer Genome Atlas Bladder Urothelial Carcinoma AMIGO1 0.10 0.14 enet 10 0.11 2.8e-09 4.3 5.2 1.8e-07 0.03 0.77 0.22 FALSE
10 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SYPL2 0.03 0.05 lasso 4 0.05 6.6e-06 5.4 5.5 3.4e-08 0.02 0.03 0.96 FALSE
11 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma AMIGO1 0.06 0.00 blup 46 0.02 9.5e-03 4.3 5.8 9.2e-09 0.04 0.03 0.37 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma SYPL2 0.08 0.08 blup 44 0.10 1.9e-10 5.6 5.6 2.3e-08 0.03 0.02 0.98 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma ATXN7L2 0.06 0.06 lasso 3 0.05 6.6e-06 5.6 -5.6 2.5e-08 -0.03 0.01 0.98 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma SYPL2 0.07 0.04 blup 45 0.03 4.9e-04 5.6 -5.5 4.3e-08 -0.02 0.02 0.98 FALSE