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chr3:158,296,916-161,490,079

Best TWAS P=4.94e-19 · Best GWAS P=7.11e-162 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	IFT80	0.08	0.06	enet	35	0.06	1.5e-07	-5.04	6.4	1.7e-10	0.16	1.00	0.00	TRUE
2	CommonMind	Brain Pre-frontal Cortex	SCHIP1	0.15	0.12	bslmm	624	0.12	6.9e-14	-4.84	6.1	8.3e-10	0.19	1.00	0.00	TRUE
3	CommonMind	Brain Pre-frontal Cortex	TRIM59	0.03	0.01	blup	379	0.01	3.1e-02	-4.65	6.2	7.5e-10	0.10	0.60	0.01	TRUE
4	GTEx	Brain Cortex	IFT80	0.15	0.09	lasso	3	0.04	2.5e-02	7.27	8.9	4.9e-19	0.27	0.27	0.08	TRUE
5	GTEx	Brain Frontal Cortex BA9	PPM1L	0.18	0.13	enet	23	0.07	6.5e-03	-4.85	-5.2	1.6e-07	-0.09	0.23	0.28	TRUE
6	GTEx	Liver	KRT8P12	0.21	0.02	enet	14	0.14	1.2e-04	0.99	6.2	5.6e-10	0.16	0.06	0.18	TRUE
7	GTEx	Testis	KPNA4	0.14	0.04	enet	21	0.06	1.7e-03	4.34	7.7	1.4e-14	0.19	0.63	0.02	TRUE
8	METSIM	Adipose	IFT80	0.03	0.00	blup	397	0.01	1.8e-02	7.28	8.4	3.1e-17	0.26	0.11	0.03	FALSE
9	YFS	Blood	KPNA4	0.02	0.02	lasso	6	0.01	6.7e-05	5.36	5.2	1.9e-07	0.20	0.58	0.03	TRUE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIM59	0.01	0.01	blup	41	0.01	7.8e-04	7.27	6.9	5.2e-12	0.19	0.00	0.96	TRUE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SMC4	0.04	0.03	lasso	3	0.02	9.9e-04	7.20	6.7	1.9e-11	0.23	0.00	0.98	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TRIM59	0.05	0.08	lasso	2	0.09	9.4e-11	-5.05	5.3	1.2e-07	0.12	1.00	0.00	FALSE
13	The Cancer Genome Atlas	Brain Lower Grade Glioma	IFT80	0.03	0.02	blup	94	0.02	3.1e-03	7.20	6.2	6.1e-10	0.15	0.21	0.34	FALSE
14	The Cancer Genome Atlas	Brain Lower Grade Glioma	IL12A	0.08	0.07	enet	14	0.07	1.1e-08	9.23	8.1	4.5e-16	0.33	1.00	0.00	TRUE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	TRIM59	0.04	0.01	blup	41	0.02	7.0e-04	-4.42	5.8	7.2e-09	0.17	0.07	0.75	TRUE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	TRIM59	0.02	0.01	blup	41	0.01	1.4e-02	5.36	5.5	3.1e-08	0.13	0.05	0.26	FALSE
17	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SMC4	0.04	0.01	blup	43	0.02	1.3e-03	7.27	5.4	8.4e-08	0.14	0.00	0.83	FALSE
18	The Cancer Genome Atlas	Thyroid Carcinoma	TRIM59	0.02	0.02	blup	41	0.02	8.0e-03	-5.05	5.3	8.7e-08	0.10	0.08	0.19	FALSE