[Hub]/) : Traits : Mouth/teeth dental problems: Mouth ulcers : ← →

chr3:45,262,393-47,544,003

Best TWAS P=1.56e-54 · Best GWAS P=2.81e-52 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
42	The Cancer Genome Atlas	Rectum Adenocarcinoma	CCR3	0.20	0.11	lasso	3	0.10	2.7e-03	15.20	15.6	1.6e-54	0.97	0.00	0.89	TRUE
26	The Cancer Genome Atlas	Colon Adenocarcinoma	CCR1	0.08	0.01	blup	28	0.02	2.1e-02	-8.95	-12.0	2.1e-33	-0.36	0.01	0.24	TRUE
6	GTEx	Cells Transformed fibroblasts	CCR1	0.13	0.07	lasso	6	0.07	8.9e-06	-8.95	-8.9	4.9e-19	-0.20	1.00	0.00	TRUE
11	GTEx	Lung	FYCO1	0.20	0.16	enet	17	0.16	4.4e-12	-9.07	-8.2	1.6e-16	-0.32	1.00	0.00	TRUE
23	YFS	Blood	CCR5	0.04	0.03	lasso	5	0.04	5.2e-13	-8.59	-7.4	1.3e-13	-0.68	1.00	0.00	TRUE
21	NTR	Blood	FYCO1	0.02	0.01	lasso	1	0.01	5.6e-05	5.68	5.7	1.4e-08	0.10	0.90	0.00	TRUE
43	The Cancer Genome Atlas	Thyroid Carcinoma	CCR3	0.07	0.01	blup	76	0.01	1.3e-02	-12.10	13.6	4.6e-42	0.53	0.03	0.14	FALSE
28	The Cancer Genome Atlas	Glioblastoma Multiforme	CCR3	0.23	0.13	enet	8	0.13	8.3e-05	-12.10	13.2	1.0e-39	0.48	0.04	0.42	FALSE
35	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CCR1	0.03	0.02	blup	28	0.02	1.5e-03	-12.10	-12.2	2.4e-34	-0.40	0.00	0.94	FALSE
39	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCR2	0.10	0.01	enet	15	0.05	7.1e-06	5.75	-12.2	2.7e-34	-0.78	0.01	0.51	FALSE
14	GTEx	Thyroid	FYCO1	0.20	0.13	lasso	9	0.13	2.0e-10	-8.48	-11.0	4.7e-28	-0.43	1.00	0.00	FALSE
19	NTR	Blood	CCR3	0.19	0.12	lasso	13	0.22	3.9e-69	-12.10	10.8	3.6e-27	0.39	1.00	0.00	FALSE
15	GTEx	Whole Blood	CCR1	0.12	0.10	lasso	4	0.09	4.8e-09	-8.77	-10.6	2.6e-26	-0.44	0.99	0.00	FALSE
24	YFS	Blood	CXCR6	0.05	0.04	lasso	13	0.06	8.5e-19	-8.53	10.3	8.0e-25	0.35	1.00	0.00	FALSE
10	GTEx	Esophagus Muscularis	FYCO1	0.17	0.06	lasso	8	0.08	1.7e-05	-9.07	-9.9	4.7e-23	-0.37	0.80	0.01	FALSE
20	NTR	Blood	CXCR6	0.02	0.02	lasso	5	0.02	2.4e-06	-8.21	9.8	7.0e-23	0.34	0.96	0.01	FALSE
1	GTEx	Adipose Subcutaneous	FYCO1	0.18	0.12	lasso	4	0.12	9.8e-10	-9.07	-9.4	3.7e-21	-0.35	0.99	0.00	FALSE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FYCO1	0.10	0.10	blup	79	0.10	7.1e-11	-9.07	-9.1	8.2e-20	-0.34	0.00	1.00	FALSE
18	NTR	Blood	CCR1	0.17	0.12	enet	34	0.19	3.7e-59	-12.10	-8.7	2.7e-18	-0.14	1.00	0.00	FALSE
34	The Cancer Genome Atlas	Lung Adenocarcinoma	FYCO1	0.04	0.04	lasso	2	0.03	5.3e-04	-8.48	-8.6	9.1e-18	-0.29	0.01	0.96	FALSE
22	YFS	Blood	CCR1	0.49	0.30	bslmm	457	0.38	2.0e-133	-8.80	-8.2	2.3e-16	-0.26	1.00	0.00	FALSE
31	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CCR3	0.07	0.00	blup	76	0.03	1.0e-04	-8.76	8.1	5.0e-16	0.17	0.10	0.03	FALSE
5	GTEx	Cells Transformed fibroblasts	FYCO1	0.26	0.14	enet	14	0.22	3.9e-16	-7.64	-7.9	2.1e-15	-0.29	1.00	0.00	FALSE
3	GTEx	Artery Aorta	LRRC2	0.08	0.00	enet	14	0.00	2.5e-01	5.59	7.7	1.7e-14	0.32	0.08	0.12	FALSE
16	METSIM	Adipose	FYCO1	0.11	0.10	lasso	6	0.14	2.4e-20	-7.54	-7.4	9.9e-14	-0.27	1.00	0.00	FALSE
17	METSIM	Adipose	PRSS50	0.03	0.02	blup	365	0.02	1.3e-03	-2.97	7.3	2.5e-13	0.35	0.69	0.14	FALSE
8	GTEx	Esophagus Mucosa	FYCO1	0.17	0.08	lasso	3	0.15	2.2e-10	4.24	-7.3	3.7e-13	-0.27	1.00	0.00	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	FYCO1	0.15	0.13	lasso	5	0.13	2.8e-05	-5.21	-7.1	1.6e-12	-0.36	0.33	0.06	FALSE
9	GTEx	Esophagus Mucosa	TMIE	0.09	0.01	lasso	5	0.01	5.3e-02	-4.28	7.0	2.9e-12	0.43	0.09	0.05	FALSE
2	GTEx	Artery Aorta	FYCO1	0.14	0.02	enet	13	0.08	4.4e-05	-8.48	-7.0	3.6e-12	-0.28	0.77	0.03	FALSE
44	The Cancer Genome Atlas	Thyroid Carcinoma	FYCO1	0.16	0.10	enet	14	0.14	2.1e-13	3.15	-6.9	4.1e-12	-0.26	0.59	0.41	FALSE
37	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	FYCO1	0.08	0.03	enet	12	0.04	8.1e-04	-5.26	-6.7	2.5e-11	-0.33	0.01	0.94	FALSE
30	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FYCO1	0.08	0.01	blup	81	0.04	3.9e-05	3.58	-6.7	2.8e-11	-0.22	0.08	0.45	FALSE
33	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FYCO1	0.07	0.02	lasso	6	0.02	1.4e-02	4.74	-6.6	5.3e-11	-0.26	0.01	0.74	FALSE
38	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	FYCO1	0.34	0.13	blup	78	0.18	1.1e-07	4.71	-6.5	8.0e-11	-0.34	0.09	0.64	FALSE
41	The Cancer Genome Atlas	Prostate Adenocarcinoma	FYCO1	0.14	0.17	blup	81	0.18	2.7e-18	3.15	-6.5	9.2e-11	-0.24	1.00	0.00	FALSE
13	GTEx	Skin Sun Exposed Lower leg	FYCO1	0.17	0.08	lasso	8	0.19	1.5e-15	4.24	-6.4	1.3e-10	-0.31	1.00	0.00	FALSE
12	GTEx	Nerve Tibial	FYCO1	0.26	0.24	enet	25	0.27	2.8e-19	-5.21	-6.2	4.9e-10	-0.38	1.00	0.00	FALSE
36	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FYCO1	0.06	0.02	lasso	6	0.05	2.7e-06	3.19	-6.0	1.9e-09	-0.30	0.09	0.90	FALSE
29	The Cancer Genome Atlas	Glioblastoma Multiforme	LTF	0.24	0.11	lasso	5	0.09	9.5e-04	4.38	5.5	3.0e-08	0.04	0.05	0.05	FALSE
4	GTEx	Brain Cortex	LRRC2	0.35	0.10	enet	29	0.15	6.6e-05	-0.63	5.5	3.2e-08	0.32	0.13	0.09	FALSE
25	The Cancer Genome Atlas	Breast Invasive Carcinoma	FYCO1	0.06	0.05	blup	81	0.07	1.6e-13	4.00	-5.4	6.5e-08	-0.18	1.00	0.00	FALSE
45	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	CCR5	0.12	0.04	blup	32	0.06	8.4e-03	-8.59	-5.3	1.2e-07	-0.63	0.00	0.42	FALSE
27	The Cancer Genome Atlas	Colon Adenocarcinoma	FYCO1	0.07	0.02	blup	79	0.04	1.5e-03	4.00	-5.2	1.6e-07	-0.30	0.05	0.38	FALSE
40	The Cancer Genome Atlas	Prostate Adenocarcinoma	CCR5	0.09	0.06	enet	5	0.08	2.8e-08	-8.59	-5.2	2.1e-07	-0.65	0.93	0.01	FALSE