TWAS hub - KRT8P12

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Liver	0.211	0.099	7.8e-03	0.016	NA	0.137	NA	0.049	1.1e-01	NA	1.2e-04	NA	0.017
2	GTEx	Testis	0.198	0.064	6.0e-06	0.150	NA	0.121	NA	0.015	3.4e-07	NA	5.1e-06	NA	0.068

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Mouth/teeth dental problems: Mouth ulcers	17.1	27.2	38.4	6.2	-4.0
Illnesses of mother	9.7	12.0	12.7	3.6	-3.4
Illnesses of siblings: Diabetes	9.0	11.0	11.6	-3.2	3.4
Prospective memory result	6.6	8.1	13.3	3.6	-1.7
Prostate Cancer	6.5	9.2	9.5	3.0	-3.1
Primary Biliary Cirrhosis	6.5	9.2	11.7	-2.6	3.4
Pack years of smoking	6.3	9.2	12.4	-2.5	3.5
Pack years adult smoking proportion	6.2	9.5	14.4	-2.2	3.8
Ever used hormone-replacement therapy (HRT)	5.2	6.6	7.9	-2.3	2.8
Diabetes (mother)	5.1	6.5	7.4	-2.4	2.7
Alcohol usually taken with meals	4.5	7.3	9.8	-3.1	2.2
Systolic blood pressure, automated reading	4.3	12.6	13.7	-3.4	3.7
High blood pressure (mother)	4.2	5.8	9.1	-3.0	1.6
Medication: Ibuprofen (e.g. Nurofen)	4.2	5.3	8.4	2.9	-1.5
Diabetes (self-reported)	3.9	6.0	7.1	-2.7	2.2
Father’s age at death	3.9	5.3	6.3	-2.0	2.5
Alcohol drinker status: Previous	3.8	4.4	7.2	-1.2	2.7
Systolic Blood Pressure	3.6	18.2	21.3	-3.9	4.6
Asthma	3.5	6.9	7.1	-2.6	2.7
Cholesterol lowering medication	3.5	5.2	7.7	-1.6	2.8
Eye problems/disorders: Diabetes related eye disease	3.2	3.6	6.7	-2.6	0.7
Gout (self-reported)	3.2	4.4	8.1	-2.9	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.2	3.8	5.9	2.4	-1.3
Medication: Lisinopril	3.1	3.9	4.6	-2.1	1.8
Suffer from ‘nerves’	3.0	4.7	8.4	-2.9	1.0
Fasting Glucose	2.9	3.5	5.1	-1.4	2.3
Cardiovascular Disease	2.9	9.5	9.8	-3.0	3.1
High blood pressure (siblings)	2.9	4.1	5.0	-2.2	1.8
Medication: Allopurinol	2.9	3.8	7.3	-2.7	0.6
Respiratory disease	2.8	6.3	7.5	-2.2	2.7
Medication: Blood pressure	2.8	5.0	7.8	-2.8	1.5
Diabetes diagnosed by doctor	2.8	4.7	5.8	-2.4	1.9
Asthma (self-reported)	2.8	5.6	5.9	-2.3	2.4
Average weekly beer plus cider intake	2.8	4.1	8.1	2.9	0.0
Miserableness	2.7	4.7	7.3	2.7	-1.4
Verbal and Numeric Reasoning (VNR)	2.6	6.3	8.0	-2.8	2.2
Ever unenthusiastic/disinterested for a whole week	2.6	3.2	5.6	2.4	-0.9
Medication for cholesterol, blood pressure or diabetes	2.6	4.4	7.0	2.7	-1.3
LDL Cholesterol	2.5	4.0	6.1	-1.4	2.5
Stomach or abdominal pain in last month	2.5	3.1	5.7	2.4	-0.7
Schizophrenia (2018)	2.4	4.9	9.2	3.0	-0.9
Number of full sisters	2.4	3.0	5.4	0.7	2.3
Smoking Status	2.3	5.6	9.9	3.1	-1.1
Hearing aid user	2.3	2.6	3.3	-1.8	1.4
High cholesterol (Self-reported)	2.3	4.1	4.4	-2.1	1.9
Number of operations (self-reported)	2.3	3.4	5.9	1.0	-2.4
Past tobacco smoking	2.2	4.0	7.0	-2.6	1.0
Mouth/teeth dental problems	2.2	3.4	5.7	-2.4	1.1
Birth weight of first child	2.2	3.9	4.7	-2.2	1.8
Coronary Artery Disease (CAD)	2.1	2.5	3.3	1.8	-1.3
Illnesses of siblings	2.1	2.9	3.4	1.6	-1.9
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.5	4.8	-0.3	2.2
Reaction Time	2.0	3.9	4.9	1.7	-2.2
Glaucoma (self-reported)	2.0	2.3	4.5	0.3	2.1
Comparative body size at age 10	2.0	5.6	9.8	1.2	-3.1
Commuting to job workplace: Car/motor vehicle	2.0	2.3	3.9	-2.0	0.8
Eye problems/disorders: Glaucoma	2.0	2.3	4.6	0.1	2.1
Chronotype (morning person)	1.9	4.4	6.7	-1.4	2.6
Qualifications: CSEs or equivalent	1.9	2.6	5.1	2.2	-0.3
Overall health rating	1.9	4.1	7.0	-1.1	2.6
Number of self-reported non-cancer illnesses	1.9	3.3	3.3	-1.8	1.8
Schizophrenia vs Biploar Disorder	1.8	2.4	4.6	2.1	-0.5
Relative age of first facial hair	1.8	3.7	7.2	2.7	-0.6
Chronic bronchitis/emphysema (mother)	1.8	2.1	2.2	1.5	1.5
Alcohol intake frequency.	1.8	4.2	4.5	-2.1	2.0
Ever smoked	1.8	3.2	6.3	2.5	-0.5
Age at First Birth	1.7	2.4	3.1	1.3	-1.8
HbA1C	1.7	1.9	2.7	-1.0	1.7
Type 2 Diabetes (T2D) (2018)	1.7	3.1	4.0	-1.5	2.0
Pulse wave reflection index	1.7	2.1	3.4	0.9	-1.8
Worry too long after embarrassment	1.7	2.8	3.4	1.8	-1.5
Mean time to correctly identify matches	1.7	3.3	4.8	1.4	-2.2
Smoking status: Current	1.7	2.7	4.0	2.0	1.2
Intelligence (Savage-Jansen 2018)	1.6	5.1	6.8	-2.6	1.8
Waist Hip Ratio (WHR)	1.6	7.2	8.1	2.9	-2.5
Lung FVC	1.6	8.3	13.2	1.8	-3.6
Number of treatments/medications taken	1.6	2.9	3.6	-1.5	1.9
Supplements: Glucosamine	1.6	2.1	4.2	0.3	2.0
Mouth/teeth dental problems: Dentures	1.6	2.7	3.0	-1.5	1.7
Age at last live birth	1.6	2.3	3.1	1.8	-1.2
Hypertension (Self-reported)	1.6	4.6	5.4	-2.3	1.9
Current tobacco smoking	1.5	2.5	2.9	1.4	1.7
Allergy	1.5	3.5	5.1	1.4	-2.3
Medication: Ibuprofen	1.5	1.8	3.3	1.8	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.1	5.4	-2.3	0.9
Age started oral contraceptive pill	1.5	1.9	3.8	-2.0	0.0
Neuroticism (2016)	1.4	2.1	2.2	-1.4	1.5
Supplements: Zinc	1.4	1.5	3.0	1.7	-0.3
Angina (self-reported)	1.4	1.8	3.6	-0.1	1.9
Basal cell carcinoma (self-reported)	1.4	1.7	2.5	1.6	0.9
Alzheimer’s Disease (in mother)	1.3	1.5	1.8	-1.3	1.1
Blood Red Count	1.3	12.3	13.1	3.6	-3.4
Hand grip strength (right)	1.3	3.5	5.9	-2.4	1.0
High blood pressure	1.3	3.6	3.7	-1.9	1.9
Fluid intelligence score	1.3	2.8	3.5	-1.9	1.5
Breastfed as a baby	1.3	1.6	3.1	1.8	-0.2
Tense / ‘highly strung’	1.3	2.1	2.5	-1.6	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.7	5.2	0.5	-2.3
Vascular/heart problems diagnosed by doctor	1.3	3.6	4.0	1.8	-2.0
Bipolar Disorder or Schizophrenia	1.2	2.8	5.4	2.3	0.4
Schizophrenia (2014)	1.2	2.7	5.3	2.3	0.3
Blood Eosinophil Count	1.2	9.3	17.3	-1.2	4.2
Angina	1.2	1.6	3.1	0.3	1.8
Average weekly fortified wine intake	1.2	1.4	2.7	-1.7	0.3
Fed-up feelings	1.2	2.2	3.4	1.8	-1.0
Frequency of tiredness / lethargy in last 2 weeks	1.2	2.0	3.3	1.8	0.8
Medication: Seretide 50 evohaler	1.2	1.3	2.4	-1.5	0.6
Had major operations	1.2	1.4	2.2	0.7	-1.5
Guilty feelings	1.2	1.8	3.1	0.8	-1.8
Unable to work because of sickness or disability	1.2	1.6	3.1	-0.2	1.8
Irritable Bowel Disease (IBD)	1.1	2.6	3.2	1.8	-1.5
Average weekly spirits intake	1.1	1.4	2.1	0.9	-1.4
Chronic bronchitis/emphysema (father)	1.1	1.3	2.3	0.5	1.5
Frequency of tenseness / restlessness in last 2 weeks	1.1	1.7	3.4	-0.1	1.9
Pain all over the body in last month	1.1	1.2	2.1	-1.4	-0.5
Loud music exposure frequency	1.1	1.2	1.9	1.4	0.6
Exposure to tobacco smoke outside home	1.1	1.4	1.8	1.3	1.0
Number of full brothers	1.1	1.4	1.5	1.2	1.1
Supplements: Calcium	1.1	1.2	1.4	1.0	1.2
Bipolar Disorder (2018)	1.0	1.5	3.0	-0.0	1.7
Hypothyroidism (self reported)	1.0	2.4	3.0	-1.3	1.7
Sensitivity / hurt feelings	1.0	1.7	1.9	1.4	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	2.4	1.6	0.5
Tinnitus: Yes, but not now, but have in the past	1.0	1.0	2.1	1.4	-0.0
Lung cancer (father)	1.0	1.2	2.0	1.4	-0.6
Hair/balding pattern: Pattern 4	1.0	2.5	2.8	-1.7	1.5
Wheeze or whistling in the chest in last year	1.0	1.8	3.5	-0.2	1.9
Number of children fathered	1.0	1.1	1.2	-1.1	1.0
Heart disease (mother)	1.0	1.3	1.5	-1.2	1.0
Medication: Gliclazide	1.0	1.2	2.0	-1.4	0.6
Medication: Metformin	0.9	1.3	1.6	-1.2	1.0
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.0	-0.4	1.4
Qualifications: None of the above	0.9	1.9	3.8	-0.0	2.0
Hip circumference	0.9	4.1	8.1	-2.8	0.3
Falls in the last year	0.9	1.2	2.3	1.5	0.3
Leg pain on walking	0.9	1.1	2.2	-0.2	1.5
Smoking status: Previous	0.9	1.3	1.6	1.2	-1.0
Illnesses of father: None of the above (group 1)	0.9	1.1	1.5	0.8	-1.2
Ulcerative Colitis (UC)	0.8	1.4	1.7	1.3	-1.1
Multivitamins +/- minerals	0.8	1.0	1.7	1.3	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.8	1.8	2.9	0.8	-1.7
Medication: Ramipril	0.8	1.0	1.2	-1.1	0.9
Alcohol intake versus 10 years previously	0.8	1.2	1.4	-1.2	1.0
Length of working week for main job	0.8	0.8	1.3	-0.6	-1.1
Age at first live birth	0.8	1.5	2.3	0.8	-1.5
Emphysema/chronic bronchitis	0.8	1.0	1.7	0.4	-1.3
Chest pain or discomfort	0.8	1.1	2.2	-0.1	1.5
Commuting to job workplace: Walk	0.8	0.8	1.3	0.6	-1.1
Back pain experienced in last month	0.8	1.1	2.2	-0.0	1.5
Pain type(s) experienced in last month: Hip pain	0.8	1.0	1.9	-0.3	1.4
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	1.1	-0.9	1.1
Worry (Nagel 2018)	0.7	1.4	2.8	-1.7	0.1
Crohns Disease (2017)	0.7	1.5	1.9	1.4	-1.0
Bipolar Disorder (2011)	0.7	0.7	0.8	0.9	0.8
HDL Cholesterol	0.7	1.1	1.6	-0.8	1.3
Allergy or Eczema	0.7	1.9	2.3	-1.5	1.2
Vitamin and mineral supplements	0.7	0.9	1.2	-1.1	0.7
Townsend deprivation index at recruitment	0.7	1.0	1.3	0.9	1.1
Relative age voice broke	0.7	1.1	2.3	1.5	0.0
Number of incorrect matches in round	0.7	1.2	2.2	-0.3	1.5
Hair/balding pattern: Pattern 2	0.7	0.8	1.4	1.2	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	0.9	-0.9	0.8
Blood clot in the leg (DVT)	0.7	0.8	0.9	-0.9	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	1.4	-0.6	1.2
Qualifications: nursing, teaching	0.7	1.0	1.7	-1.3	-0.6
Osteoarthritis (self-reported)	0.7	0.9	1.7	1.3	0.2
Medication: Aspirin	0.7	0.9	1.4	-1.2	0.6
Mother’s age at death	0.7	0.8	1.2	-0.7	-1.1
Ever had prostate specific antigen (PSA) test	0.7	0.8	1.5	0.0	-1.2
Pain experienced in last month	0.7	1.2	2.2	-1.5	-0.4
Arm predicted mass (left)	0.7	3.5	6.5	-2.5	-0.8
Crohns Disease (2012)	0.6	0.9	1.3	1.1	-0.8
Rheumatoid Arthritis	0.6	0.8	1.4	-0.4	1.2
Heel T-Score	0.6	4.9	5.0	2.2	-2.2
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.5	-1.2	-0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.3	1.9	0.9	-1.4
Hayfever, allergic rhinitis or eczema	0.6	1.2	2.1	-0.6	1.5
Medication: Simvastatin	0.6	0.8	0.9	-0.9	0.9
Weight	0.6	2.8	5.1	-2.3	-0.6
Mouth/teeth dental problems: Bleeding gums	0.6	0.8	1.2	0.7	-1.1
Headache pain in last month	0.6	1.0	1.3	1.1	-0.8
Arm predicted mass (right)	0.6	3.1	5.6	-2.4	-0.8
Knee pain experienced in last month	0.6	0.9	1.0	1.0	0.9
Medication for cholesterol	0.6	0.8	1.5	0.4	-1.2
Tinnitus: Yes, now most or all of the time	0.6	0.7	1.2	-1.1	0.4
Supplements: Fish oil (including cod liver oil)	0.6	0.7	1.3	-0.4	1.1
Medication: Atorvastatin	0.6	0.8	1.3	-1.1	0.5
Basal metabolic rate	0.6	3.1	4.8	-2.2	-1.1
Arm fat-free mass (left)	0.6	2.9	4.8	-2.2	-1.0
Ever depressed for a whole week	0.6	0.8	1.3	1.1	-0.5
Myopia	0.6	0.8	1.5	1.2	-0.4
Triglycerides	0.5	0.8	1.2	-1.1	0.6
Lung FEV1/FVC ratio	0.5	2.5	2.6	-1.6	1.5
Ever had hysterectomy (womb removed)	0.5	0.6	1.2	-1.1	0.1
Severe depression (siblings)	0.5	0.5	0.8	0.9	0.5
Leg fat-free mass (left)	0.5	2.5	3.5	-1.9	-1.2
Leg predicted mass (left)	0.5	2.5	3.5	-1.9	-1.2
Trunk fat-free mass	0.5	3.0	4.9	-2.2	-1.1
Worrier / anxious feelings	0.5	1.0	1.5	0.7	-1.2
Qualifications: A levels/AS levels or equivalent	0.5	1.0	1.5	-0.7	-1.2
Medication: Lansoprazole	0.5	0.6	1.1	1.1	-0.2
Pulse wave Arterial Stiffness index	0.5	0.6	0.6	-0.8	0.8
Trunk predicted mass	0.5	2.9	4.7	-2.2	-1.0
Exposure to tobacco smoke at home	0.5	0.6	1.0	1.0	0.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	0.8	0.9	-0.9
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.1	1.1	-0.3
Comparative height size at age 10	0.5	2.7	3.5	-1.9	-1.4
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	0.9	1.0	-0.5
Illnesses of father: Heart disease	0.5	0.7	0.8	-0.9	0.8
Whole body fat-free mass	0.5	3.0	4.4	-2.1	-1.3
Leg fat-free mass (right)	0.5	2.5	3.2	-1.8	-1.3
Whole body water mass	0.5	3.0	4.1	-2.0	-1.4
Leg predicted mass (right)	0.5	2.6	3.2	-1.8	-1.4
Ever taken oral contraceptive pill	0.5	0.6	0.6	0.8	-0.7
Financial situation satisfaction	0.5	0.6	0.7	0.8	-0.8
Medication: Paracetamol	0.5	0.8	0.8	-0.9	0.9
Heart attack/myocardial infarction (self-reported)	0.5	0.6	0.8	-0.6	0.9
Depressed Affect (Nagel 2018)	0.4	0.9	1.1	1.0	-0.9
Depression (Nagel 2018)	0.4	0.6	1.0	1.0	-0.4
Ovarian Cancer	0.4	0.5	1.0	-0.2	-1.0
Hand grip strength (left)	0.4	0.9	1.9	-1.4	-0.0
Medication for hormone replacement therapy	0.4	0.4	0.6	-0.8	-0.4
Impedance of leg (right)	0.4	1.9	3.8	0.2	1.9
Maternal smoking around birth	0.4	0.5	0.9	0.4	0.9
Taking other prescription medications	0.4	0.6	0.7	-0.8	0.8
Impedance of leg (left)	0.4	2.0	4.0	0.1	2.0
Had other major operations	0.4	0.5	1.0	0.1	-1.0
Number of live births	0.4	0.6	0.9	1.0	-0.4
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	2.4	-0.7	-1.6
Noisy workplace	0.4	0.5	0.8	0.9	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.2	1.7	-0.8	-1.3
Arm fat mass (right)	0.4	1.7	3.3	-1.8	-0.2
Forced vital capacity (FVC), Best measure	0.4	1.4	2.7	-0.1	-1.6
Arm fat-free mass (right)	0.4	2.3	4.1	-2.0	-0.7
Neck or shoulder pain in last month	0.4	0.6	0.7	0.8	0.7
Leg fat mass (right)	0.4	1.5	2.9	-1.7	0.3
Mood swings	0.4	0.7	1.5	1.2	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.4	0.7	0.4	0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	0.8	0.2	-0.9
Average weekly champagne plus white wine intake	0.4	0.6	0.8	-0.6	0.9
Illnesses of father: High blood pressure	0.4	0.5	1.0	-0.2	1.0
Fractured/broken bones in last 5 years	0.4	0.5	0.6	0.8	-0.6
Commuting to job workplace: Cycle	0.4	0.4	0.5	0.7	-0.6
Neuroticism (Nagel 2018)	0.3	0.7	1.1	0.4	-1.1
Body Mass Index (BMI) (2010)	0.3	0.3	0.6	0.3	0.8
Type 2 Diabetes (T2D) (2012)	0.3	0.3	0.4	-0.4	-0.7
Blood Platelet Count	0.3	3.1	3.2	-1.7	1.8
Hearing difficulty/problems: Yes	0.3	0.5	0.8	-0.9	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	0.5	-0.7	-0.4
Medication: Atenolol	0.3	0.3	0.6	0.8	-0.3
Trunk fat mass	0.3	1.3	2.5	-1.6	-0.3
Forced vital capacity (FVC)	0.3	1.2	2.2	-0.5	-1.5
Heart attack	0.3	0.4	0.6	-0.5	0.8
Neuroticism score	0.3	0.7	0.9	0.7	-0.9
Pulse rate	0.3	0.4	0.9	-0.1	0.9
Medication: Cholesterol lowering	0.3	0.5	0.9	-1.0	0.4
Standing height	0.3	3.4	6.0	-2.4	-0.9
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.4	-0.4	0.6
Birth weight	0.3	0.6	1.2	-0.2	-1.1
Health satisfaction	0.3	0.4	0.7	-0.4	0.8
Migraine (self-reported)	0.3	0.4	0.5	-0.7	0.5
Whole body fat mass	0.3	1.1	2.2	-1.5	-0.1
Supplements: Vitamin C	0.3	0.3	0.5	0.7	-0.5
Mineral and other dietary supplements	0.3	0.4	0.7	-0.8	-0.3
Diastolic blood pressure, automated reading	0.3	1.0	1.3	-1.1	0.9
Leg fat mass (left)	0.3	1.3	2.6	-1.6	0.2
Major Depression (MDD)	0.2	0.2	0.4	0.7	0.1
Blood White Count	0.2	1.2	1.3	-1.1	1.1
Height	0.2	3.9	6.0	-1.4	-2.4
Frequency of depressed mood in last 2 weeks	0.2	0.3	0.5	0.7	-0.1
Medication: Co-codamol	0.2	0.2	0.4	-0.3	0.6
Diabetes (father)	0.2	0.2	0.4	-0.1	0.6
Sitting height	0.2	1.5	1.6	-1.2	-1.3
Body mass index (BMI)	0.2	0.7	1.3	-1.1	-0.3
Waist circumference	0.2	0.7	1.0	-1.0	-0.6
Nervous feelings	0.2	0.4	0.6	-0.5	0.8
Hearing difficulty/problems with background noise	0.2	0.3	0.5	0.7	0.4
Arm fat percentage (right)	0.2	0.8	1.5	-1.2	0.1
Time employed in main current job	0.2	0.2	0.5	-0.1	-0.7
Hair/balding pattern: Pattern 3	0.2	0.2	0.5	0.0	0.7
Impedance of arm (left)	0.2	0.9	1.5	1.2	0.5
Peak expiratory flow (PEF)	0.2	0.4	0.7	-0.2	-0.8
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.4	-0.6	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	0.5	-0.6	0.7
Medication: Amlodipine	0.2	0.3	0.6	-0.8	-0.2
Leg fat percentage (right)	0.2	0.9	1.4	-1.2	0.5
Pulse wave peak to peak time	0.2	0.3	0.5	0.2	-0.7
Medication for pain relief, constipation, heartburn	0.2	0.4	0.7	-0.8	0.3
Illness, injury, bereavement, stress in last 2 years	0.2	0.2	0.3	-0.3	0.6
Medication: Aspirin	0.2	0.3	0.5	-0.7	0.4
Average weekly red wine intake	0.2	0.3	0.3	-0.6	-0.5
Long-standing illness, disability or infirmity	0.2	0.4	0.5	-0.7	0.4
Arm fat mass (left)	0.2	0.9	1.7	-1.3	-0.3
Commuting to job workplace: Public transport	0.2	0.2	0.3	-0.4	0.5
Medication: Blood pressure	0.2	0.3	0.6	0.8	-0.1
Medication: Bendroflumethiazide	0.2	0.3	0.5	-0.1	-0.7
Leg fat percentage (left)	0.2	0.7	1.1	-1.0	0.5
Impedance of whole body	0.2	1.1	1.2	1.0	1.1
Breast Cancer	0.1	0.4	0.7	0.2	-0.8
Mean Putamen Volume	0.1	0.2	0.3	-0.5	0.0
Lupus	0.1	0.1	0.1	-0.3	0.4
Ulcerative Colitis	0.1	0.1	0.1	-0.3	-0.3
BMI	0.1	0.7	1.5	-1.2	0.1
Hair Pigment	0.1	2.1	4.2	2.0	-0.3
Trunk fat percentage	0.1	0.5	1.0	-1.0	0.0
Age when periods started (menarche)	0.1	0.3	0.6	0.8	-0.1
Medication: Levothyroxine sodium	0.1	0.1	0.2	-0.4	0.3
Had menopause	0.1	0.2	0.4	0.1	0.6
Financial difficulties in last 2 years	0.1	0.1	0.1	0.4	0.4
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.2	-0.4	0.0
Impedance of arm (right)	0.1	0.4	0.7	0.8	0.2
Happiness	0.1	0.1	0.2	0.4	0.1
Medication: Paracetamol	0.1	0.1	0.2	-0.4	0.2
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.1	0.3	0.3
Body fat percentage	0.1	0.5	1.0	-1.0	0.2
Shortness of breath walking on level ground	0.1	0.1	0.3	-0.1	0.5
Qualifications: College or University degree	0.1	0.3	0.5	0.3	-0.7
Medication: Omeprazole	0.1	0.1	0.2	0.1	-0.4
Pulse rate, automated reading	0.1	0.2	0.3	-0.5	-0.5
Family relationship satisfaction	0.1	0.1	0.1	-0.2	-0.3
Arm fat percentage (left)	0.1	0.3	0.6	-0.8	0.0
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	-0.2	-0.5
Loneliness, isolation	0.1	0.1	0.2	0.4	-0.1
Ever had bowel cancer screening	0.1	0.1	0.2	-0.0	0.4
Eye problems/disorders: Cataract	0.1	0.1	0.2	0.4	-0.2
Osteoporosis (self-reported)	0.1	0.1	0.2	-0.4	-0.3
Wears glasses or contact lenses	0.1	0.1	0.2	-0.5	0.2
Risk taking	0.1	0.1	0.2	0.3	0.4
Medication: Omeprazole (e.g. Zanprol)	0.1	0.1	0.2	-0.1	-0.5
Heart disease (siblings)	0.1	0.1	0.1	0.4	0.2
Alzheimer’s Disease (in father)	0.0	0.0	0.0	0.2	0.1
Alzheimer’s Disease (including proxy)	0.0	0.1	0.1	-0.3	0.0
Neuroticism	0.0	0.1	0.2	-0.2	-0.4
Tanning	0.0	0.4	0.8	-0.1	-0.9
Serious illness, injury or assault to yourself	0.0	0.1	0.1	-0.3	0.0
Depression (self-reported)	0.0	0.0	0.0	0.0	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.1	0.1	-0.1	-0.3
Eye problems/disorders: None of the above	0.0	0.0	0.1	-0.1	-0.3
Friendships satisfaction	0.0	0.0	0.0	-0.2	-0.1
Breast cancer (self-reported)	0.0	0.1	0.1	-0.1	-0.3
Alcohol drinker status: Never	0.0	0.0	0.0	-0.2	-0.0
Irritability	0.0	0.1	0.1	0.4	0.0

Hub : Genes

KRT8P12

Models

Trait associations