Best TWAS P=6.81e-11 · Best GWAS P=1.9e-17 conditioned to 3.76e-15
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | NSUN6 | 0.18 | 0.11 | lasso | 8 | 0.10 | 4.9e-08 | 3.5 | -5.3 | 1.1e-07 | -0.14 | 1.00 | 0 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CACNB2 | 0.05 | 0.05 | enet | 4 | 0.04 | 8.8e-06 | -5.3 | -6.5 | 6.8e-11 | -0.03 | 0.99 | 0 | TRUE |