TWAS
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Traits
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Traits
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Vascular/heart problems diagnosed by doctor
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chr10:18,221,643-19,601,824
Best TWAS P=6.81e-11 · Best GWAS P=1.9e-17 conditioned to 3.76e-15
18.2M
18.4M
18.6M
18.8M
19M
19.2M
19.4M
19.6M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
CACNB2
0.05
0.05
enet
4
0.04
8.8e-06
-5.3
-6.5
6.8e-11
-0.03
0.99
0
TRUE
1
GTEx
Artery Tibial
NSUN6
0.18
0.11
lasso
8
0.10
4.9e-08
3.5
-5.3
1.1e-07
-0.14
1.00
0
TRUE