[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr10:62,473,976-65,606,229

Best TWAS P=5.37e-12 · Best GWAS P=6.36e-28 conditioned to 7.5e-26

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Skin Sun Exposed Lower leg	NRBF2	0.06	0.01	lasso	3	0.00	4.0e-01	5.8	-6.9	5.4e-12	0.05	0.08	0.17	TRUE
1	CommonMind	Brain Pre-frontal Cortex	TMEM26	0.27	0.15	enet	14	0.27	2.8e-32	-3.7	-5.4	8.1e-08	-0.17	1.00	0.00	TRUE
8	The Cancer Genome Atlas	Lung Adenocarcinoma	ADO	0.14	0.05	blup	53	0.05	3.8e-06	5.8	-6.8	1.4e-11	0.00	0.01	0.99	FALSE
3	GTEx	Muscle Skeletal	RP11-436D10.3	0.08	0.04	enet	13	0.06	3.2e-06	6.5	-6.4	1.6e-10	0.02	0.00	1.00	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	ADO	0.12	0.10	lasso	5	0.09	5.2e-09	6.5	-6.3	2.4e-10	0.02	0.00	1.00	FALSE
9	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ADO	0.06	0.04	blup	55	0.01	1.4e-01	6.5	-5.6	1.6e-08	0.08	0.00	0.86	FALSE
7	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ADO	0.10	0.03	enet	6	0.06	4.6e-07	-4.9	-5.5	4.1e-08	0.03	0.00	0.99	FALSE
2	GTEx	Muscle Skeletal	ADO	0.15	0.16	lasso	8	0.16	1.1e-15	-5.1	-5.4	7.5e-08	-0.01	0.73	0.27	FALSE
5	ROSMAP	Brain Pre-frontal Cortex	ADO	0.06	0.04	lasso	2	0.06	3.1e-08	6.5	-5.2	1.6e-07	0.06	0.00	1.00	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	TMEM26	0.09	0.05	lasso	5	0.08	1.2e-10	-4.3	-5.1	2.9e-07	-0.10	0.99	0.00	FALSE