Best TWAS P=1.07e-07 · Best GWAS P=2.05e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | APOPT1 | 0.17 | 0.07 | lasso | 3 | 0.08 | 0.00465 | -5.2 | 5.2 | 2.1e-07 | -0.94 | 0.02 | 0.85 | FALSE |
| 2 | GTEx | Nerve Tibial | KLC1 | 0.07 | 0.00 | enet | 22 | 0.01 | 0.08530 | -3.9 | -5.2 | 2.2e-07 | 0.63 | 0.07 | 0.71 | FALSE |
| 3 | GTEx | Spleen | KLC1 | 0.15 | 0.05 | lasso | 3 | 0.03 | 0.06370 | -5.2 | -5.3 | 1.3e-07 | 0.92 | 0.03 | 0.66 | FALSE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | MARK3 | 0.12 | 0.05 | blup | 64 | 0.07 | 0.00329 | 4.0 | 5.2 | 2.6e-07 | -0.63 | 0.02 | 0.20 | FALSE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | C14orf153 | 0.20 | 0.05 | lasso | 2 | 0.04 | 0.00088 | -5.2 | 5.3 | 1.1e-07 | -0.97 | 0.00 | 0.95 | TRUE |