[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr15:40,360,741-42,749,023

Best TWAS P=5.36e-12 · Best GWAS P=8.92e-12 conditioned to 0.169

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	GTEx	Skin Sun Exposed Lower leg	CHP1	0.06	0.04	enet	9	0.04	3.1e-04	-6.6	6.9	5.4e-12	-0.90	0.02	0.95	TRUE
1	CommonMind	Brain Pre-frontal Cortex	EXD1	0.04	0.04	lasso	3	0.04	8.1e-06	-6.4	6.3	2.7e-10	-0.94	0.04	0.95	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	CHP	0.01	0.01	blup	54	0.01	1.4e-02	-6.8	6.2	4.4e-10	-0.92	0.01	0.90	FALSE
3	GTEx	Colon Sigmoid	NDUFAF1	0.15	0.06	lasso	4	0.06	5.2e-03	-5.3	6.1	1.3e-09	-0.70	0.16	0.60	FALSE
4	GTEx	Esophagus Mucosa	CHP1	0.19	0.10	lasso	7	0.09	1.4e-06	-5.8	6.0	2.2e-09	-0.94	0.02	0.98	FALSE
5	GTEx	Lung	OIP5-AS1	0.09	0.08	enet	14	0.12	2.8e-09	-6.6	-5.8	4.9e-09	0.88	0.02	0.98	FALSE
8	NTR	Blood	INO80	0.02	0.02	enet	8	0.03	2.8e-09	-5.6	5.8	6.2e-09	-0.84	0.49	0.51	FALSE
9	YFS	Blood	MGA	0.01	0.00	blup	454	0.00	7.1e-02	-5.9	-5.7	1.4e-08	0.69	0.02	0.82	FALSE
2	GTEx	Brain Cortex	GCHFR	0.25	0.04	enet	15	0.05	1.4e-02	-5.5	5.5	4.0e-08	-0.77	0.04	0.71	FALSE
6	GTEx	Skin Not Sun Exposed Suprapubic	NDUFAF1	0.16	0.06	lasso	3	0.07	1.7e-04	-5.3	5.4	7.4e-08	-0.50	0.09	0.12	FALSE
11	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	INO80	0.07	0.04	blup	40	0.06	1.2e-03	-4.4	-5.2	1.8e-07	0.80	0.03	0.66	FALSE
12	The Cancer Genome Atlas	Thyroid Carcinoma	INO80	0.03	0.02	blup	39	0.03	1.0e-03	-2.2	-5.2	2.0e-07	0.78	0.06	0.85	FALSE