Best TWAS P=6.98e-08 · Best GWAS P=2.46e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | PDXK | 0.14 | 0.11 | lasso | 3 | 0.12 | 6.2e-07 | -5.3 | -5.4 | 7.0e-08 | 0.97 | 0.03 | 0.97 | TRUE |
| 2 | GTEx | Esophagus Mucosa | PDXK | 0.29 | 0.18 | enet | 12 | 0.24 | 4.1e-16 | -5.3 | -5.1 | 3.0e-07 | 0.84 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Vagina | PDXK | 0.23 | 0.19 | lasso | 1 | 0.23 | 5.2e-06 | -5.3 | -5.3 | 1.5e-07 | 0.90 | 0.05 | 0.92 | FALSE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | HSF2BP | 0.16 | -0.01 | blup | 62 | 0.02 | 4.7e-02 | 2.3 | 5.3 | 9.7e-08 | -0.87 | 0.01 | 0.22 | FALSE |