Best TWAS P=4.27e-20 · Best GWAS P=1.11e-65 conditioned to 1.84e-42
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C4orf22 | 0.09 | 0.08 | lasso | 5 | 0.07 | 4.5e-09 | 8.5 | 9.2 | 4.3e-20 | 0.59 | 1.00 | 0.00 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | FGF5 | 0.07 | 0.06 | lasso | 2 | 0.05 | 5.4e-07 | 8.5 | 8.0 | 9.2e-16 | 0.53 | 0.76 | 0.14 | FALSE |
| 3 | GTEx | Nerve Tibial | PRDM8 | 0.14 | 0.14 | lasso | 3 | 0.13 | 1.0e-09 | -5.2 | -5.2 | 2.4e-07 | -0.19 | 1.00 | 0.00 | TRUE |