[Hub]/) : Traits : Allergy :

chr4:122,377,715-124,935,698

Best TWAS P=8.01e-34 · Best GWAS P=2.67e-30 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex KIAA1109 0.09 0.08 bslmm 390 0.08 8.9e-10 -11.3 8.4 3.0e-17 -0.91 0.01 0.99 FALSE
2 GTEx Artery Aorta KIAA1109 0.11 0.00 lasso 7 0.01 5.1e-02 -11.4 10.1 5.7e-24 -0.88 0.03 0.82 FALSE
3 GTEx Artery Tibial KIAA1109 0.16 0.07 lasso 6 0.05 5.1e-05 -11.1 10.9 1.0e-27 -0.97 0.01 0.98 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia KIAA1109 0.22 0.07 lasso 7 0.03 5.9e-02 -11.1 10.7 6.3e-27 -0.97 0.02 0.67 FALSE
5 GTEx Colon Transverse KIAA1109 0.25 -0.01 enet 16 0.00 4.1e-01 -10.9 11.2 7.0e-29 -0.86 0.02 0.76 FALSE
6 GTEx Colon Transverse BBS12 0.12 0.05 enet 29 0.12 3.2e-06 1.9 -5.3 1.3e-07 0.52 0.07 0.28 FALSE
7 ROSMAP Brain Pre-frontal Cortex KIAA1109 0.08 0.08 lasso 7 0.07 2.5e-09 -11.1 10.9 1.0e-27 -0.98 0.01 0.99 FALSE
8 ROSMAP Brain Pre-frontal Cortex SPATA5 0.05 0.01 bslmm 485 0.01 1.2e-02 -3.1 6.6 3.2e-11 -0.13 0.17 0.05 TRUE
9 The Cancer Genome Atlas Breast Invasive Carcinoma KIAA1109 0.03 0.03 lasso 1 0.02 1.2e-05 -11.1 11.1 1.1e-28 -0.99 0.05 0.92 FALSE
10 The Cancer Genome Atlas Esophageal Carcinoma KIAA1109 0.32 0.02 blup 45 0.02 7.4e-02 -10.9 12.1 8.0e-34 -0.66 0.01 0.47 TRUE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma KIAA1109 0.05 0.05 enet 8 0.04 1.3e-05 -11.1 8.2 1.7e-16 -0.93 0.02 0.95 TRUE
12 The Cancer Genome Atlas Brain Lower Grade Glioma KIAA1109 0.06 0.05 lasso 2 0.03 7.1e-05 -11.1 11.3 1.6e-29 -0.99 0.06 0.91 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma KIAA1109 0.05 0.04 enet 3 0.05 5.4e-06 -10.9 11.7 1.6e-31 -0.95 0.01 0.98 TRUE