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chr5:34,920,257-36,637,217

Best TWAS P=5.95e-38 · Best GWAS P=2.28e-40 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IL7R	0.04	0.03	lasso	3	0.02	9.8e-04	13.3	12.9	5.9e-38	0.96	0.00	0.99	TRUE
3	GTEx	Testis	IL7R	0.25	0.19	lasso	6	0.18	2.1e-08	-5.3	-5.5	3.2e-08	-0.33	0.99	0.00	TRUE
2	GTEx	Cells Transformed fibroblasts	SPEF2	0.26	0.01	enet	56	0.04	2.6e-04	2.9	7.0	2.8e-12	0.34	0.12	0.70	FALSE
4	METSIM	Adipose	SPEF2	0.06	0.01	blup	522	0.03	4.0e-05	-4.2	6.7	1.7e-11	0.36	0.74	0.02	FALSE
7	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	UGT3A2	0.04	0.00	blup	52	0.01	4.9e-02	4.0	-6.7	2.6e-11	-0.35	0.02	0.23	FALSE
6	YFS	Blood	IL7R	0.03	0.01	bslmm	467	0.01	8.1e-05	-4.4	-6.7	2.7e-11	-0.39	0.82	0.05	FALSE
5	ROSMAP	Brain Pre-frontal Cortex	CAPSL	0.05	0.02	lasso	6	0.03	2.9e-04	-5.5	5.7	1.4e-08	0.55	0.29	0.42	FALSE
1	GTEx	Brain Frontal Cortex BA9	SPEF2	0.39	0.23	enet	27	0.22	1.8e-06	4.9	5.5	3.1e-08	0.49	0.81	0.02	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	UGT3A2	0.05	0.00	blup	52	0.02	3.4e-03	-2.9	-5.4	7.1e-08	-0.34	0.02	0.13	FALSE
8	The Cancer Genome Atlas	Breast Invasive Carcinoma	UGT3A2	0.06	0.02	blup	52	0.05	9.7e-10	-3.5	-5.4	8.5e-08	-0.30	0.97	0.02	FALSE