[Hub]/) : Traits : Allergy :

chr5:108,927,715-111,770,880

Best TWAS P=2.04e-45 · Best GWAS P=4.28e-60 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex TMEM232 0.08 0.05 lasso 4 0.05 1.6e-06 -3.17 -6.2 6.4e-10 0.10 0.92 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex WDR36 0.05 0.03 enet 13 0.01 1.0e-02 2.49 6.9 4.6e-12 0.44 0.14 0.42 FALSE
3 GTEx Adipose Visceral Omentum WDR36 0.11 0.08 lasso 4 0.10 8.7e-06 3.89 5.7 1.0e-08 0.39 0.81 0.05 FALSE
4 GTEx Artery Tibial WDR36 0.11 0.05 lasso 5 0.07 3.2e-06 3.89 5.6 2.3e-08 0.42 0.87 0.02 FALSE
5 GTEx Brain Cerebellar Hemisphere WDR36 0.32 0.12 lasso 7 0.17 4.8e-05 4.89 7.5 8.5e-14 0.33 0.11 0.14 TRUE
6 GTEx Brain Cerebellum WDR36 0.26 0.22 lasso 4 0.27 1.5e-08 4.89 5.5 3.4e-08 0.30 0.40 0.11 FALSE
7 GTEx Liver WDR36 0.32 -0.01 enet 19 0.03 5.4e-02 3.42 8.5 2.2e-17 0.64 0.06 0.34 FALSE
8 GTEx Nerve Tibial SLC25A46 0.15 0.01 enet 18 0.07 1.2e-05 -8.32 5.9 3.8e-09 0.00 0.52 0.02 FALSE
9 GTEx Skin Not Sun Exposed Suprapubic WDR36 0.17 0.09 lasso 6 0.08 2.6e-05 7.12 7.1 1.3e-12 0.44 0.66 0.25 FALSE
10 GTEx Skin Sun Exposed Lower leg WDR36 0.13 0.03 lasso 9 0.09 8.9e-08 7.12 5.4 6.2e-08 0.41 0.78 0.18 FALSE
11 GTEx Spleen SLC25A46 0.25 0.00 enet 6 0.02 1.3e-01 -8.30 7.8 7.3e-15 0.01 0.07 0.05 FALSE
12 GTEx Testis WDR36 0.61 0.37 lasso 10 0.34 5.7e-16 7.18 8.8 9.0e-19 0.57 1.00 0.00 FALSE
13 METSIM Adipose CAMK4 0.05 0.01 bslmm 518 0.03 8.3e-05 -10.09 -9.6 7.7e-22 -0.61 0.04 0.88 FALSE
14 METSIM Adipose TMEM232 0.04 0.06 lasso 8 0.06 9.8e-09 -7.36 -7.2 6.3e-13 0.08 1.00 0.00 TRUE
15 METSIM Adipose TSLP 0.16 0.18 lasso 7 0.18 8.5e-26 14.33 -14.1 2.0e-45 -0.92 0.28 0.72 TRUE
16 ROSMAP Brain Pre-frontal Cortex TSLP 0.13 0.08 enet 14 0.09 4.1e-11 13.48 -11.2 4.4e-29 -0.73 1.00 0.00 TRUE
17 ROSMAP Brain Pre-frontal Cortex CAMK4 0.10 0.03 lasso 4 0.04 7.8e-06 -10.07 10.5 1.0e-25 0.59 0.90 0.08 FALSE
18 ROSMAP Brain Pre-frontal Cortex STARD4-AS1 0.07 0.02 enet 19 0.03 5.0e-05 0.22 5.8 5.3e-09 0.39 0.06 0.81 FALSE
19 YFS Blood SLC25A46 0.03 0.02 enet 12 0.02 9.5e-07 -8.32 12.5 5.6e-36 0.25 0.95 0.00 TRUE
20 The Cancer Genome Atlas Bladder Urothelial Carcinoma CAMK4 0.04 0.04 blup 159 0.01 3.6e-02 -7.78 7.2 4.8e-13 0.14 0.26 0.04 TRUE
21 The Cancer Genome Atlas Bladder Urothelial Carcinoma TMEM232 0.08 0.06 blup 158 0.07 6.4e-07 -7.51 -6.8 1.5e-11 0.08 0.98 0.00 FALSE
22 The Cancer Genome Atlas Breast Invasive Carcinoma TSLP 0.03 0.03 lasso 2 0.03 5.5e-07 14.34 -12.4 1.8e-35 -0.84 0.00 1.00 FALSE
23 The Cancer Genome Atlas Colon Adenocarcinoma TSLP 0.08 0.01 blup 39 0.03 5.4e-03 13.52 -12.0 2.6e-33 -0.78 0.02 0.59 FALSE
24 The Cancer Genome Atlas Esophageal Carcinoma TMEM232 0.17 0.16 lasso 2 0.13 7.5e-05 -6.25 -6.1 1.4e-09 0.09 0.68 0.02 FALSE
25 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TSLP 0.03 0.00 enet 7 0.01 3.8e-02 12.17 -8.9 7.8e-19 -0.64 0.02 0.28 TRUE
26 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TMEM232 0.07 0.12 lasso 2 0.12 4.7e-13 -6.25 -6.0 2.2e-09 0.10 1.00 0.00 FALSE
27 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TSLP 0.05 0.02 blup 39 0.02 7.9e-04 13.52 -12.3 5.5e-35 -0.77 0.05 0.78 TRUE
28 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma TMEM232 0.15 0.12 lasso 2 0.16 2.2e-09 -7.64 -6.6 4.2e-11 0.09 1.00 0.00 TRUE
29 The Cancer Genome Atlas Brain Lower Grade Glioma TMEM232 0.09 0.03 blup 160 0.04 3.3e-05 -8.62 -8.2 1.8e-16 0.06 0.98 0.00 FALSE
30 The Cancer Genome Atlas Brain Lower Grade Glioma TSLP 0.06 0.07 blup 39 0.06 6.4e-07 13.52 -12.8 1.5e-37 -0.88 0.02 0.98 FALSE
31 The Cancer Genome Atlas Lung Adenocarcinoma TSLP 0.02 0.02 blup 39 0.02 1.9e-03 14.34 -12.5 4.0e-36 -0.88 0.01 0.79 FALSE
32 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TSLP 0.04 0.03 enet 6 0.02 1.6e-03 13.82 -12.9 4.6e-38 -0.86 0.02 0.85 FALSE
33 The Cancer Genome Atlas Pancreatic Adenocarcinoma TMEM232 0.17 0.03 blup 162 0.06 1.9e-03 -7.64 -7.8 5.4e-15 0.09 0.12 0.19 FALSE
34 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma TMEM232 0.07 0.03 blup 159 0.03 2.3e-02 -3.12 -5.9 3.6e-09 0.08 0.08 0.04 FALSE
35 The Cancer Genome Atlas Prostate Adenocarcinoma TMEM232 0.06 0.06 blup 161 0.08 3.7e-09 -7.47 -5.9 4.5e-09 0.11 1.00 0.00 FALSE
36 The Cancer Genome Atlas Prostate Adenocarcinoma TSLP 0.03 0.01 blup 39 0.02 2.7e-03 9.38 -10.3 5.3e-25 -0.69 0.06 0.33 FALSE
37 The Cancer Genome Atlas Stomach Adenocarcinoma WDR36 0.04 0.04 lasso 1 0.03 3.7e-03 7.10 7.1 1.2e-12 0.45 0.17 0.13 FALSE
38 The Cancer Genome Atlas Testicular Germ Cell Tumors TSLP 0.12 0.11 lasso 3 0.08 6.9e-04 14.30 -14.1 5.5e-45 -0.92 0.01 0.90 FALSE
39 The Cancer Genome Atlas Thyroid Carcinoma TMEM232 0.20 0.16 enet 17 0.24 2.3e-23 -7.30 -6.8 8.8e-12 0.10 1.00 0.00 FALSE
40 The Cancer Genome Atlas Thyroid Carcinoma TSLP 0.13 0.14 blup 39 0.15 1.4e-14 13.52 -10.5 5.7e-26 -0.75 0.04 0.96 FALSE
41 The Cancer Genome Atlas Thyroid Carcinoma WDR36 0.08 0.02 blup 73 0.05 1.5e-05 -3.96 6.2 4.8e-10 0.44 0.28 0.33 FALSE