Best TWAS P=1.37e-19 · Best GWAS P=1.04e-36 conditioned to 3.08e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ERMP1 | 0.15 | 0.09 | bslmm | 489 | 0.11 | 4.1e-13 | -2.676 | -5.1 | 2.8e-07 | 0.05 | 1.00 | 0.00 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | GLDC | 0.24 | 0.10 | lasso | 6 | 0.15 | 8.5e-18 | -4.885 | -5.3 | 1.2e-07 | 0.22 | 1.00 | 0.00 | FALSE |
| 3 | CommonMind | Brain Pre-frontal Cortex | KIAA1432 | 0.04 | 0.00 | blup | 514 | 0.03 | 2.7e-04 | 0.075 | -6.9 | 5.7e-12 | 0.19 | 0.07 | 0.03 | TRUE |
| 4 | GTEx | Ovary | PLGRKT | 0.45 | 0.11 | enet | 30 | 0.30 | 5.8e-08 | -2.385 | -5.7 | 1.5e-08 | 0.06 | 0.20 | 0.05 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | KIAA1432 | 0.11 | 0.04 | lasso | 5 | 0.03 | 9.2e-04 | -5.515 | -5.5 | 3.8e-08 | 0.07 | 0.58 | 0.03 | TRUE |
| 6 | ROSMAP | Brain Pre-frontal Cortex | RANBP6 | 0.07 | 0.01 | blup | 396 | 0.02 | 1.7e-03 | 2.975 | -9.1 | 1.4e-19 | 0.06 | 0.89 | 0.00 | TRUE |
| 7 | ROSMAP | Brain Pre-frontal Cortex | GLDC | 0.11 | 0.00 | enet | 5 | 0.01 | 7.4e-03 | -12.632 | -8.9 | 7.5e-19 | 0.70 | 0.01 | 0.87 | TRUE |