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chr9:122,881,960-124,487,495

Best TWAS P=6.79e-10 · Best GWAS P=7.56e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	TRAF1	0.09	0.11	enet	26	0.12	1.7e-14	-6.1	5.1	2.6e-07	-0.92	0.01	0.99	FALSE
2	GTEx	Adrenal Gland	PSMD5	0.40	0.22	enet	37	0.23	7.2e-09	-4.0	-5.8	7.8e-09	0.77	0.03	0.97	FALSE
3	GTEx	Artery Aorta	C5	0.06	0.02	lasso	8	0.02	2.9e-02	-5.4	-5.8	8.1e-09	0.70	0.10	0.50	FALSE
4	GTEx	Artery Coronary	PSMD5-AS1	0.56	0.50	enet	31	0.55	1.3e-21	-4.0	-5.2	1.7e-07	0.62	0.88	0.12	FALSE
5	GTEx	Artery Tibial	TRAF1	0.04	0.05	lasso	2	0.03	1.2e-03	-5.4	-5.4	7.7e-08	0.88	0.29	0.50	FALSE
6	GTEx	Brain Caudate basal ganglia	TRAF1	0.17	0.22	lasso	11	0.20	2.1e-06	-6.2	6.1	8.2e-10	-1.00	0.01	0.98	FALSE
7	GTEx	Brain Cerebellar Hemisphere	TRAF1	0.42	0.24	lasso	10	0.16	6.8e-05	-6.1	5.8	7.0e-09	-0.95	0.01	0.98	FALSE
8	GTEx	Brain Cerebellum	TRAF1	0.42	0.24	enet	26	0.34	7.2e-11	-6.1	5.4	7.5e-08	-0.88	0.01	0.99	FALSE
9	GTEx	Brain Nucleus accumbens basal ganglia	TRAF1	0.29	0.25	lasso	12	0.22	1.9e-06	-6.1	6.1	1.3e-09	-0.98	0.01	0.98	FALSE
10	GTEx	Brain Putamen basal ganglia	TRAF1	0.26	0.21	lasso	6	0.19	2.3e-05	-6.2	6.0	1.5e-09	-0.98	0.02	0.97	FALSE
11	GTEx	Muscle Skeletal	TRAF1	0.10	0.02	lasso	7	0.01	1.9e-02	-6.1	5.2	1.9e-07	-0.92	0.01	0.99	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	TRAF1	0.25	0.17	lasso	12	0.16	4.4e-09	-5.5	-5.7	1.0e-08	0.92	0.04	0.96	FALSE
13	GTEx	Skin Sun Exposed Lower leg	TRAF1	0.11	0.09	lasso	5	0.09	1.4e-07	-5.4	-5.3	1.5e-07	0.79	0.49	0.51	FALSE
14	GTEx	Testis	TRAF1	0.25	0.27	lasso	3	0.27	1.8e-12	-6.1	6.1	9.9e-10	-1.00	0.01	0.99	FALSE
15	YFS	Blood	PHF19	0.05	0.03	enet	21	0.04	2.9e-14	-5.4	5.2	2.1e-07	-0.80	0.11	0.89	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRAF1	0.04	0.04	lasso	3	0.05	7.2e-10	-6.1	6.2	6.8e-10	-0.99	0.01	0.99	TRUE
17	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TRAF1	0.05	0.00	blup	56	0.02	1.9e-02	-5.2	5.9	3.6e-09	-0.95	0.01	0.71	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	PHF19	0.03	0.03	lasso	2	0.02	3.6e-03	-5.2	5.3	1.1e-07	-0.83	0.04	0.60	FALSE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	TRAF1	0.07	0.06	blup	53	0.08	1.7e-08	-6.1	5.5	3.6e-08	-0.91	0.02	0.98	FALSE
20	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PSMD5	0.23	0.09	blup	41	0.16	3.6e-06	-6.2	-5.8	5.9e-09	0.84	0.00	0.99	FALSE